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Kinoshita Tarou

木下　タロウ

Center for Infectious Disease Education and Research, Specially Appointed Professor

Education

  • 1977 - 1981, Osaka University, Graduate School of Medicine, Bacteriology
  • 1974 - 1977, The University of Tokyo, Graduate School of Agricultural Science
  • 1972 - 1974, The University of Tokyo
  • 1970 - 1972, The University of Tokyo

Research History

  • 2024/04 - Present, Osaka University, Specially-appointed Professor
  • 2007 - Present, Osaka University, Immunology Frontier Research Center, Principal Investigator
  • 2022/04 - 2024/04, Osaka University
  • 2022/04 - 2024/04, Osaka University, Research Institute for Microbial Diseases
  • 2017 - 2022, Osaka University, Yabumoto Department of Intractable Disease Research, Research Institute for Microbial Diseases, Endowed Chair Professor
  • 1990 - 2017, Osaka University, Department of Immunoregulation, Research Institute for Microbial Diseases, Professor
  • 2003 - 2007, Osaka University, Research Institute for Microbial Diseases, Director
  • 1988 - 1990, Osaka University, Department of Bacteriology, Medical School, Assistant Professor
  • 1982 - 1988, Osaka University, Department of Bacteriology, Medical School, Research Associate
  • 1981 - 1982, Osaka University, Department of Bacteriology, Medical School, Postdoctoral Fellow supported by Japan Society for Promotion of Sciences

Research Areas

  • Life sciences, Functional biochemistry
  • Life sciences, Immunology
  • Life sciences, Structural biochemistry

Professional Memberships

  • 国際補体学会(International Complement Society)
  • アメリカ免疫学会(American Association of Immunologists)
  • 生体防御学会
  • 日本生化学会
  • ì˙ñ{ç◊ã€äwâÔ J^
  • 日本免疫学会

Papers

  • AAV-based gene therapy ameliorated CNS-specific GPI defect in mouse models, Yoshiko Murakami,Saori Umeshita,Kae Imanishi,Yoshichika Yoshioka,Akinori Ninomiya,Takehiko Sunabori,Shibi Likhite,Masato Koike,Kathrin C. Meyer,Taroh Kinoshita, Molecular Therapy - Methods & Clinical Development, Elsevier BV, Vol. 32, No. 1, p. 101176-101176, 2024/03
  • The role of lipid scramblases in regulating lipid distributions at cellular membranes., Yicheng Wang,Taroh Kinoshita, Biochemical Society transactions, 2023/09/28
  • A lipid scramblase TMEM41B is involved in the processing and transport of GPI-anchored proteins., Shu-Ya Cao,Yi-Shi Liu,Xiao-Dong Gao,Taroh Kinoshita,Morihisa Fujita, Journal of biochemistry, Vol. 174, No. 2, p. 109-123, 2023/07/31
  • Accumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1., Yi-Shi Liu,Yicheng Wang,Xiaoman Zhou,Linpei Zhang,Ganglong Yang,Xiao-Dong Gao,Yoshiko Murakami,Morihisa Fujita,Taroh Kinoshita, The Journal of cell biology, Vol. 222, No. 5, 2023/05/01
  • A point mutation in GPI-attachment signal peptide accelerates the development of prion disease., Atsushi Kobayashi,Tetsuya Hirata,Taishi Shimazaki,Yoshiko Munesue,Keisuke Aoshima,Takashi Kimura,Junko Nio-Kobayashi,Rie Hasebe,Atsuko Takeuchi,Yuichi Matsuura,Satoshi Kusumi,Daisuke Koga,Yasushi Iwasaki,Taroh Kinoshita,Shirou Mohri,Tetsuyuki Kitamoto, Acta neuropathologica, Vol. 145, No. 5, p. 637-650, 2023/05
  • Mitigating Drug-Target-Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors., Jun-Ichi Nishimura,Antoine Soubret,Noriko Arase,Simon Buatois,Masaki Hotta,Jean-Eric Charoin,Yoshikazu Ito,Sasha Sreckovic,Hiroyuki Takamori,Christoph Bucher,Yasutaka Ueda,Jules Hernández-Sánchez,Keisuke Gotanda,Gregor Jordan,Kenji Shinomiya,Julia Ramos,Jin Seok Kim,Jens Panse,Régis Peffault de Latour,Alexander Röth,Eiichi Morii,Hubert Schrezenmeier,Yoshitaka Isaka,Simona Sica,Yuzuru Kanakura,Sung-Soo Yoon,Taroh Kinoshita,Ido Paz-Priel,Alexandre Sostelly, Clinical pharmacology and therapeutics, Vol. 113, No. 4, p. 904-915, 2023/04
  • Case report: Functional analysis of the p.Arg507Trp variant of the PIGT gene supporting the moderate epilepsy phenotype of mutations in the C-terminal region., Ikhlas Ben Ayed,Olfa Jallouli,Yoshiko Murakami,Amal Souissi,Salma Mallouli,Amal Bouzid,Fatma Kamoun,Ines Elloumi,Fakher Frikha,Abdelaziz Tlili,Sarah Weckhuysen,Taroh Kinoshita,Chahnez Charfi Triki,Saber Masmoudi, Frontiers in neurology, Vol. 14, p. 1092887-1092887, 2023/03
  • Excluding Digenic Inheritance of PGAP2 and PGAP3 Variants in Mabry Syndrome (OMIM 239300) Patient: Phenotypic Spectrum Associated with PGAP2 Gene Variants in Hyperphosphatasia with Mental Retardation Syndrome-3 (HPMRS3)., Miles D Thompson,Xueying Li,Michele Spencer-Manzon,Danielle M Andrade,Yoshiko Murakami,Taroh Kinoshita,Thomas O Carpenter, Genes, Vol. 14, No. 2, 2023/01/30
  • Biallelic variants in PIGN cause Fryns syndrome, multiple congenital anomalies-hypotonia-seizures syndrome, and neurologic phenotypes: A genotype-phenotype correlation study., Lucy Loong,Agostina Tardivo,Alexej Knaus,Mona Hashim,Alistair T Pagnamenta,Kerstin Alt,Helena Böhrer-Rabel,Alfonso Caro-Llopis,Trevor Cole,Felix Distelmaier,Patrick Edery,Carlos R Ferreira,Aleksandra Jezela-Stanek,Bronwyn Kerr,Gerhard Kluger,Peter M Krawitz,Marius Kuhn,Johannes R Lemke,Gaetan Lesca,Sally Ann Lynch,Francisco Martinez,Caroline Maxton,Hanna Mierzewska,Sandra Monfort,Joost Nicolai,Carmen Orellana,Deb K Pal,Rafał Płoski,Oliver W Quarrell,Monica Rosello,Małgorzata Rydzanicz,Ataf Sabir,Robert Śmigiel,Alexander P A Stegmann,Helen Stewart,Constance Stumpel,Elżbieta Szczepanik,Andreas Tzschach,Lynne Wolfe,Jenny C Taylor,Yoshiko Murakami,Taroh Kinoshita,Allan Bayat,Usha Kini, Genetics in medicine : official journal of the American College of Medical Genetics, Vol. 25, No. 1, p. 37-48, 2023/01
  • Sequential hydrolysis of FAD by ecto-5' nucleotidase CD73 and alkaline phosphatase is required for uptake of vitamin B2 into cells., Natsuki Shichinohe,Daisuke Kobayashi,Ayaka Izumi,Kazuya Hatanaka,Rio Fujita,Taroh Kinoshita,Norimitsu Inoue,Naoya Hamaue,Keiji Wada,Yoshiko Murakami, The Journal of biological chemistry, Vol. 298, No. 12, p. 102640-102640, 2022/12
  • 【補体と疾患-いま補体がおもしろい-】補体活性化とその制御, 井上 徳光,木下 タロウ, 日本臨床, (株)日本臨床社, Vol. 80, No. 11, p. 1706-1712, 2022/11
  • Case report: Functional characterization of a de novo c.145G>A p.Val49Met pathogenic variant in a case of PIGA-CDG with megacolon., Roberta Salinas-Marín,Yoshiko Murakami,Carlos Alberto González-Domínguez,Mario Ernesto Cruz-Muñoz,Héctor Manuel Mora-Montes,Eva Morava,Taroh Kinoshita,Susana Monroy-Santoyo,Iván Martínez-Duncker, Frontiers in genetics, Vol. 13, p. 971473-971473, 2022/10
  • ER entry pathway and glycosylation of GPI-anchored proteins are determined by N-terminal signal sequence and C-terminal GPI-attachment sequence., Tetsuya Hirata,Jing Yang,Seita Tomida,Yuko Tokoro,Taroh Kinoshita,Morihisa Fujita,Yasuhiko Kizuka, The Journal of biological chemistry, Vol. 298, No. 10, p. 102444-102444, 2022/10
  • C18orf32 loss-of-function is associated with a neurodevelopmental disorder with hypotonia and contractures., Smrithi Salian,Xin-Yu Guo,Yoshiko Murakami,Taroh Kinoshita,Parneet Kaur,Anju Shukla,Katta M Girisha,Morihisa Fujita,Philippe M Campeau, Human genetics, Vol. 141, No. 8, p. 1423-1429, 2022/08/01
  • Ethanolamine-phosphate on the second mannose is a preferential bridge for some GPI-anchored proteins., Mizuki Ishida,Yuta Maki,Akinori Ninomiya,Yoko Takada,Philippe Campeau,Taroh Kinoshita,Yoshiko Murakami, EMBO reports, Vol. 23, No. 7, 2022/07/05
  • Establishment of mouse model of inherited PIGO deficiency and therapeutic potential of AAV-based gene therapy., Ryoko Kuwayama,Keiichiro Suzuki,Jun Nakamura,Emi Aizawa,Yoshichika Yoshioka,Masahito Ikawa,Shin Nabatame,Ken-Ichi Inoue,Yoshiari Shimmyo,Keiichi Ozono,Taroh Kinoshita,Yoshiko Murakami, Nature communications, Vol. 13, No. 1, p. 3107-3107, 2022/06/03
  • Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis., Yicheng Wang,Anant K Menon,Yuta Maki,Yi-Shi Liu,Yugo Iwasaki,Morihisa Fujita,Paula A Guerrero,Daniel Varó'n Silva,Peter H Seeberger,Yoshiko Murakami,Taroh Kinoshita, Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 14, 2022/04/05
  • Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology., Tetsuya Hirata,Atsushi Kobayashi,Tamio Furuse,Ikuko Yamada,Masaru Tamura,Hiroyuki Tomita,Yuko Tokoro,Akinori Ninomiya,Yoshitaka Fujihara,Masahito Ikawa,Yusuke Maeda,Yoshiko Murakami,Yasuhiko Kizuka,Taroh Kinoshita, The Journal of biological chemistry, Vol. 298, No. 3, p. 101720-101720, 2022/03/01
  • Differential use of p24 family members as cargo receptors for the transport of glycosylphosphatidylinositol-anchored proteins and Wnt1., Yuko Tashima,Tetsuya Hirata,Yusuke Maeda,Yoshiko Murakami,Taroh Kinoshita, Journal of biochemistry, Vol. 171, No. 1, p. 75-83, 2022/01/07
  • Rescue of Glycosylphosphatidylinositol-Anchored Protein Biosynthesis Using Synthetic Glycosylphosphatidylinositol Oligosaccharides., Paula A Guerrero,Yoshiko Murakami,Ankita Malik,Peter H Seeberger,Taroh Kinoshita,Daniel Varón Silva, ACS chemical biology, Vol. 16, No. 11, p. 2297-2306, 2021/11/19
  • Functional analysis of the gpi transamidase complex by screening for amino acid mutations in each subunit, Si Si Liu,Fei Jin,Yi Shi Liu,Yoshiko Murakami,Yukihiko Sugita,Takayuki Kato,Xiao Dong Gao,Taroh Kinoshita,Motoyuki Hattori,Morihisa Fujita, Molecules, Vol. 26, No. 18, 2021/09/01
  • CLPTM1L is a lipid scramblase involved in glycosylphosphatidylinositol biosynthesis, Yicheng Wang,Anant K. Menon,Yuta Maki,Yi-Shi Liu,Yugo Iwasaki,Morihisa Fujita,Paula A. Guerrero,Daniel Varón Silva,Peter H. Seeberger,Yoshiko Murakami,Taroh Kinoshita, bioRxiv, Cold Spring Harbor Laboratory, 2021/07/14
  • Inherited glycosylphosphatidylinositol defects cause the rare Emm-negative blood phenotype and developmental disorders, Romain Duval,Gaël Nicolas,Alexandra Willemetz,Yoshiko Murakami,Mahmoud Mikdar,Cedric Vrignaud,Hisham Megahed,Jean Pierre Cartron,Cecile Masson,Samer Wehbi,Bérengere Koehl,Marie Hully,Karine Siquier,Nicole Chemlay,Agnes Rotig,Stanislas Lyonnet,Yves Colin,Giulia Barcia,Vincent Cantagrel,Caroline Le Van Kim,Olivier Hermine,Taroh Kinoshita,Thierry Peyrard,Slim Azouzi, Blood, Vol. 137, No. 26, p. 3660-3669, 2021/07/01
  • Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals, Jing Yang,Tetsuya Hirata,Yi Shi Liu,Xin Yu Guo,Xiao Dong Gao,Taroh Kinoshita,Morihisa Fujita, FEBS Letters, Vol. 595, No. 11, p. 1542-1558, 2021/06/01
  • A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins, Si Si Liu,Yi Shi Liu,Xin Yu Guo,Yoshiko Murakami,Ganglong Yang,Xiao Dong Gao,Taroh Kinoshita,Morihisa Fujita, Communications Biology, Vol. 4, No. 1, 2021/06/01
  • PIGF deficiency causes a phenotype overlapping with DOORS syndrome, Smrithi Salian,Hind Benkerroum,Thi Tuyet Mai Nguyen,Sheela Nampoothiri,Taroh Kinoshita,Têmis Maria Félix,Fiona Stewart,Sanjay M. Sisodiya,Yoshiko Murakami,Philippe M. Campeau, Human Genetics, Vol. 140, No. 6, p. 879-884, 2021/06/01
  • PIGO variants in a boy with features of Mabry syndrome who also exhibits Fryns syndrome with peripheral neuropathy, Taro Okuda,Takahiro Yonekawa,Yoshiko Murakami,Taroh Kinoshita,Takahiro Ito,Kohei Matsushita,Yuhki Koike,Mikihiro Inoue,Keiichi Uchida,Noriko Yodoya,Hiroyuki Ohashi,Hirofumi Sawada,Shotaro Iwamoto,Yoshihide Mitani,Masahiro Hirayama, American Journal of Medical Genetics, Part A, Vol. 185, No. 3, p. 845-849, 2021/03/01
  • Early infancy-onset stimulation-induced myoclonic seizures in three siblings with inherited glycosylphosphatidylinositol (GPI) anchor deficiency, Yukiko Mogami,Yasuhiro Suzuki,Yoshiko Murakami,Tae Ikeda,Sadami Kimura,Keiko Yanagihara,Nobuhiko Okamoto,Taroh Kinoshita, Epileptic Disorders, Wiley Blackwell, Vol. 20, No. 1, p. 42-50, 2021/02
  • Hrd1-dependent degradation of the unassembled pigk subunit of the gpi transamidase complex, Kohei Kawaguchi,Miki Yamamoto-Hino,Yoshiko Murakami,Taroh Kinoshita,Satoshi Goto, Cell Structure and Function, Vol. 46, No. 2, p. 65-71, 2021
  • PIGG variant pathogenicity assessment reveals characteristic features within 19 families, Camille Tremblay-Laganière,Reza Maroofian,Thi Tuyet Mai Nguyen,Ehsan Ghayoor Karimiani,Salman Kirmani,Fizza Akbar,Shahnaz Ibrahim,Bushra Afroze,Mohammad Doosti,Farah Ashrafzadeh,Meisam Babaei,Stephanie Efthymiou,Marilena Christoforou,Tipu Sultan,Roger L. Ladda,Heather M. McLaughlin,Rebecca Truty,Sonal Mahida,Julie S. Cohen,Kristin Baranano,Fatima Y. Ismail,Millan S. Patel,Anna Lehman,Andrew C. Edmondson,Amanda Nagy,Melissa A. Walker,Saadet Mercimek-Andrews,Yuta Maki,Rani Sachdev,Rebecca Macintosh,Elizabeth E. Palmer,Grazia M.S. Mancini,Tahsin Stefan Barakat,Robert Steinfeld,Christina T. Rüsch,Georg M. Stettner,Matias Wagner,Saskia B. Wortmann,Usha Kini,Angela F. Brady,Karen L. Stals,Naila Ismayilova,Sian Ellard,Danilo Bernardo,Kimberly Nugent,Scott D. McLean,Stylianos E. Antonarakis,Henry Houlden,Taroh Kinoshita,Philippe M. Campeau,Yoshiko Murakami, Genetics in Medicine, Vol. 23, No. 10, p. 1873-1881, 2021
  • 遺伝性血管性浮腫(Hereditary angioedema:HAE)診療ガイドライン 改訂2019年版, 堀内 孝彦,大澤 勲,今井 優樹,大谷 克城,関根 英治,塚本 浩,中尾 実樹,西村 純一,水野 正司,村上 良子,山本 哲郎,木下 タロウ,大井 洋之,井上 徳光,若宮 伸隆,野々山 恵章,一般社団法人日本補体学会, 厚生労働省難治性疾患等政策研究事業「原発性免疫不全症候群の診断基準・重症度分類および診療ガイドラインの確立に関する研究」研究班, 補体, (一社)日本補体学会, Vol. 57, No. 1, p. 3-22, 2020/12
  • Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation, Yicheng Wang,Yusuke Maeda,Yi Shi Liu,Yoko Takada,Akinori Ninomiya,Tetsuya Hirata,Morihisa Fujita,Yoshiko Murakami,Taroh Kinoshita, Nature Communications, Vol. 11, No. 1, p. 860-860, 2020/12/01
  • Calnexin mediates the maturation of GPI-anchors through ER retention, Xin Yu Guo,Yi Shi Liu,Xiao Dong Gao,Taroh Kinoshita,Morihisa Fujita, Journal of Biological Chemistry, Vol. 295, No. 48, p. 16393-16410, 2020/11/27
  • Paroxysmal nocturnal hemoglobinuria caused by CN-LOH of constitutional PIGB mutation and 70-kbp microdeletion on 15q, Saskia Langemeijer,Charlotte Schaap,Frank Preijers,Joop H. Jansen,Nicole Blijlevens,Norimitsu Inoue,Petra Muus,Taroh Kinoshita,Yoshiko Murakami, Blood Advances, Vol. 4, No. 22, p. 5755-5761, 2020/11/24
  • PGAP6, a GPI-specific phospholipase A2, has narrow substrate specificity against GPI-anchored proteins, Gun Hee Lee,Morihisa Fujita,Hideki Nakanishi,Haruhiko Miyata,Masahito Ikawa,Yusuke Maeda,Yoshiko Murakami,Taroh Kinoshita, Journal of Biological Chemistry, Vol. 295, No. 42, p. 14501-14509, 2020/10/16
  • α2,3 linkage of sialic acid to a GPI anchor and an unpredicted GPI attachment site in human prion protein, Atsushi Kobayashi,Tetsuya Hirata,Takashi Nishikaze,Akinori Ninomiya,Yuta Maki,Yoko Takada,Tetsuyuki Kitamoto,Taroh Kinoshita, Journal of Biological Chemistry, Vol. 295, No. 22, p. 7789-7798, 2020/05/28
  • A post glycosylphosphatidylinositol (GPI) attachment to proteins, type 2 (PGAP2) variant identified in Mabry syndrome index cases: Molecular genetics of the prototypical inherited GPI disorder, Miles D. Thompson,Alexej A. Knaus,Bruce A. Barshop,Almuth Caliebe,Hiltrud Muhle,Thi Tuyet Mai Nguyen,Nissan V. Baratang,Taroh Kinoshita,Maire E. Percy,Philippe M. Campeau,Yoshiko Murakami,David E. Cole,Peter M. Krawitz,C. Charlton Mabry, European Journal of Medical Genetics, Vol. 63, No. 4, 2020/04/01
  • Bi-allelic Variants in the GPI Transamidase Subunit PIGK Cause a Neurodevelopmental Syndrome with Hypotonia, Cerebellar Atrophy, and Epilepsy, Thi Tuyet Mai Nguyen,Yoshiko Murakami,Sabrina Mobilio,Marcello Niceta,Giuseppe Zampino,Christophe Philippe,Sébastien Moutton,Maha S. Zaki,Kiely N. James,Damir Musaev,Weiyi Mu,Kristin Baranano,Jessica R. Nance,Jill A. Rosenfeld,Nancy Braverman,Andrea Ciolfi,Francisca Millan,Richard E. Person,Ange Line Bruel,Christel Thauvin-Robinet,Athina Ververi,Catherine DeVile,Alison Male,Stephanie Efthymiou,Reza Maroofian,Henry Houlden,Shazia Maqbool,Fatima Rahman,Nissan V. Baratang,Justine Rousseau,Anik St-Denis,Matthew J. Elrick,Irina Anselm,Lance H. Rodan,Marco Tartaglia,Joseph Gleeson,Taroh Kinoshita,Philippe M. Campeau, American Journal of Human Genetics, Vol. 106, No. 4, p. 484-495, 2020/04/01
  • Complement and inflammasome overactivation mediates paroxysmal nocturnal hemoglobinuria with autoinflammation, Britta Höchsmann,Yoshiko Murakami,Makiko Osato,Alexej Knaus,Michi Kawamoto,Norimitsu Inoue,Tetsuya Hirata,Shogo Murata,Markus Anliker,Thomas Eggermann,Marten Jäger,Ricarda Floettmann,Alexander Höllein,Sho Murase,Yasutaka Ueda,Nishimura Jun-Ichi,Yuzuru Kanakura,Nobuo Kohara,Hubert Schrezenmeier,Peter M. Krawitz,Taroh Kinoshita, Journal of Clinical Investigation, Vol. 129, No. 12, p. 5123-5136, 2019/12/02
  • Mutations in PIGB Cause an Inherited GPI Biosynthesis Defect with an Axonal Neuropathy and Metabolic Abnormality in Severe Cases, Yoshiko Murakami,Thi Tuyet Mai Nguyen,Nissan Baratang,Praveen K. Raju,Alexej Knaus,Sian Ellard,Gabriela Jones,B. Lace,Justine Rousseau,Norbert Fonya Ajeawung,Atsushi Kamei,Gaku Minase,Manami Akasaka,Nami Araya,E. Koshimizu,Jenneke van den Ende,Florian Erger,Janine Altmüller,Zita Krumina,Jurgis Strautmanis,Inna Inashkina,J. Stavusis,A. El-Gharbawy,Jessica Sebastian,Ratna Dua Puri,Samarth Kulshrestha,Ishwar C. Verma,Esther M. Maier,Tobias B. Haack,Anil Israni,J. Baptista,Adam Gunning,Jill A. Rosenfeld,Pengfei Liu,Marieke Joosten,María Eugenia Rocha,Mais O. Hashem,Hesham M. Aldhalaan,Fowzan S. Alkuraya,Satoko Miyatake,Naomichi Matsumoto,Peter M. Krawitz,Elsa Rossignol,T. Kinoshita,Philippe M. Campeau, American Journal of Human Genetics, Vol. 105, No. 2, p. 384-394, 2019/08/01
  • Mutations in PIGU Impair the Function of the GPI Transamidase Complex, Causing Severe Intellectual Disability, Epilepsy, and Brain Anomalies, Alexej Knaus,F. Kortüm,Tjitske Kleefstra,Asbjørg Stray-Pedersen,D. Đukić,Yoshiko Murakami,Thorsten Gerstner,Hans van Bokhoven,Z. Iqbal,Denise Horn,T. Kinoshita,Maja Hempel,Peter M. Krawitz, American Journal of Human Genetics, Vol. 105, No. 2, p. 395-402, 2019/08/01
  • Cerebellar neurodegeneration and neuronal circuit remodeling in golgi pH regulator-deficient mice, Yu Shin Sou,Soichiro Kakuta,Yuji Kamikubo,Kazue Niisato,Takashi Sakurai,Laxmi Kumar Parajuli,Isei Tanida,Hiromitsu Saito,Noboru Suzuki,Kenji Sakimura,Yusuke Maeda,Taroh Kinoshita,Yasuo Uchiyama,Masato Koike, eNeuro, Vol. 6, No. 3, p. 1-22, 2019/05/01
  • Free, unlinked glycosylphosphatidylinositols on mammalian cell surfaces revisited, Yicheng Wang,Tetsuya Hirata,Yusuke Maeda,Yoshiko Murakami,Morihisa Fujita,Taroh Kinoshita, Journal of Biological Chemistry, Vol. 294, No. 13, p. 5038-5049, 2019/03/29
  • Glycans in infection and immunity, Takashi Suzuki,Masatoshi Okamatsu,Yoshihiro Sakoda,Taroh Kinoshita,Takane Katayama,Hiroshi Kiyono,Yoshiyuki Goto,Kaoru Takegawa,Naoaki Yokoyama,Yukari Fujimoto,Takashi Angata,Katsuki Ohtani,Nobutaka Wakamiya,Hisashi Arase,Shoko Nishihara,Yasuo Suda, Glycoscience: Basic Science to Applications: Insights from the Japan Consortium for Glycobiology and Glycotechnology (JCGG), p. 227-257, 2019/01/01
  • Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain, Tetsuya Hirata,Sushil K. Mishra,Shota Nakamura,Kazunobu Saito,Daisuke Motooka,Yoko Takada,Noriyuki Kanzawa,Yoshiko Murakami,Yusuke Maeda,Morihisa Fujita,Yoshiki Yamaguchi,Taroh Kinoshita, Nature Communications, Vol. 9, No. 1, p. 405-405, 2018/12/01
  • Mutations in PIGS, Encoding a GPI Transamidase, Cause a Neurological Syndrome Ranging from Fetal Akinesia to Epileptic Encephalopathy, Thi Tuyet Mai Nguyen,Yoshiko Murakami,Kristen M. Wigby,Nissan V. Baratang,Justine Rousseau,Anik St-Denis,Jill A. Rosenfeld,Stephanie C. Laniewski,Julie Jones,Alejandro D. Iglesias,Marilyn C. Jones,Diane Masser-Frye,Angela E. Scheuerle,Denise L. Perry,Ryan J. Taft,Françoise Le Deist,Miles Thompson,Taroh Kinoshita,Philippe M. Campeau, American Journal of Human Genetics, Vol. 103, No. 4, p. 602-611, 2018/10/04
  • Lipid moiety of glycosylphosphatidylinositol-anchored proteins contributes to the determination of their final destination in yeast, Takehiko Yoko-o,Mariko Umemura,Akiko Komatsuzaki,Kazutaka Ikeda,Daisuke Ichikawa,Kumiko Takase,Noriyuki Kanzawa,Kazunobu Saito,Taroh Kinoshita,Ryo Taguchi,Yoshifumi Jigami, Genes to Cells, Vol. 23, No. 10, p. 880-892, 2018/10/01
  • Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in Drosophila, Miki Yamamoto-Hino,Eri Katsumata,Emiko Suzuki,Yusuke Maeda,Taroh Kinoshita,Satoshi Goto, Journal of Cell Science, Vol. 131, No. 20, 2018/10/01
  • Congenital Defects in the Expression of the Glycosylphosphatidylinositol-Anchored Complement Regulatory Proteins CD59 and Decay-Accelerating Factor, Taroh Kinoshita, Seminars in Hematology, W.B. Saunders, Vol. 55, No. 3, p. 136-140, 2018/07
  • A homozygous variant disrupting the PIGH start-codon is associated with developmental delay, epilepsy, and microcephaly, Alistair T. Pagnamenta,Yoshiko Murakami,Consuelo Anzilotti,Hannah Titheradge,Adam J. Oates,Jenny Morton,Taroh Kinoshita,Usha Kini,Jenny C. Taylor, Human Mutation, John Wiley and Sons Inc., Vol. 39, No. 6, p. 822-826, 2018/06
  • N-Glycan-dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing, Yi Shi Liu,Xin Yu Guo,Tetsuya Hirata,Yao Rong,Daisuke Motooka,Toshihiko Kitajima,Yoshiko Murakami,Xiao Dong Gao,Shota Nakamura,Taroh Kinoshita,Morihisa Fujita, Journal of Cell Biology, Rockefeller University Press, Vol. 217, No. 2, p. 585-599, 2018/02/01
  • Recurrent aseptic meningitis with PIGT mutations: A novel pathogenesis of recurrent meningitis successfully treated by eculizumab, Michi Kawamoto,Yoshiko Murakami,Taroh Kinoshita,Nobuo Kohara, BMJ Case Reports, Vol. 2018, 2018
  • Epileptic apnea in a patient with inherited glycosylphosphatidylinositol anchor deficiency and PIGT mutations, Kosuke Kohashi,Akihiko Ishiyama,Shota Yuasa,Tomomi Tanaka,Kazushi Miya,Yuichi Adachi,Noriko Sato,Hirotomo Saitsu,Chihiro Ohba,Naomichi Matsumoto,Yoshiko Murakami,Taroh Kinoshita,Kenji Sugai,Masayuki Sasaki, Brain and Development, Elsevier B.V., Vol. 40, No. 1, p. 53-57, 2018/01
  • Mutations in GPAA1, Encoding a GPI Transamidase Complex Protein, Cause Developmental Delay, Epilepsy, Cerebellar Atrophy, and Osteopenia, Thi Tuyet Mai Nguyen,Yoshiko Murakami,Eamonn Sheridan,Sophie Ehresmann,Justine Rousseau,Anik St-Denis,Guoliang Chai,Norbert F. Ajeawung,Laura Fairbrother,Tyler Reimschisel,Alexandra Bateman,Elizabeth Berry-Kravis,Fan Xia,Jessica Tardif,David A. Parry,Clare V. Logan,Christine Diggle,Christopher P. Bennett,Louise Hattingh,Jill A. Rosenfeld,Michael Scott Perry,Michael J. Parker,Françoise Le Deist,Maha S. Zaki,Erika Ignatius,Pirjo Isohanni,Tuula Lönnqvist,Christopher J. Carroll,Colin A. Johnson,Joseph G. Gleeson,Taroh Kinoshita,Philippe M. Campeau, American Journal of Human Genetics, CELL PRESS, Vol. 101, No. 5, p. 856-865, 2017/11/02
  • Genome-wide screening uncovers the significance of N-sulfation of heparan sulfate as a host cell factor for chikungunya virus infection, Atsushi Tanaka,Uranan Tumkosit,Shota Nakamura,Daisuke Motooka,Natsuko Kishishita,Thongkoon Priengprom,Areerat Sa-ngasang,Taroh Kinoshita,Naokazu Takeda,Yusuke Maeda, Journal of Virology, American Society for Microbiology, Vol. 91, No. 13, 2017/07/01
  • Phenotype–genotype correlations of PIGO deficiency with variable phenotypes from infantile lethality to mild learning difficulties, Junpei Tanigawa,Haruka Mimatsu,Seiji Mizuno,Nobuhiko Okamoto,Daisuke Fukushi,Koji Tominaga,Hiroyuki Kidokoro,Yukako Muramatsu,Eriko Nishi,Shota Nakamura,Daisuke Motooka,Noriko Nomura,Kiyoshi Hayasaka,Tetsuya Niihori,Yoko Aoki,Shin Nabatame,Masahiro Hayakawa,Jun Natsume,Keiichi Ozono,Taroh Kinoshita,Nobuaki Wakamatsu,Yoshiko Murakami, Human Mutation, Vol. 38, No. 7, p. 805-815, 2017/07
  • Monkeypox virus host factor screen using haploid cells identifies essential role of GARP complex in extracellular virus formation, Susan Realegeno,Andreas S. Puschnik,Amrita Kumar,Cynthia Goldsmith,Jillybeth Burgado,Suryaprakash Sambhara,Victoria A. Olson,Darin Carroll,Inger Damon,Tetsuya Hirata,Taroh Kinoshita,Jan E. Carette,Panayampalli Subbian Satheshkumar, Journal of Virology, American Society for Microbiology, Vol. 91, No. 11, 2017/06/01
  • Compound heterozygous mutations in the gene PIGP are associated with early infantile epileptic encephalopathy, Devon L. Johnstone,Thi Tuyet Mai Nguyen,Yoshiko Murakami,Kristin D. Kernohan,Martine Tétreault,Claire Goldsmith,Asif Doja,Justin D. Wagner,Lijia Huang,Taila Hartley,Anik St-Denis,Francoise Le Deist,Jacek Majewski,Dennis E. Bulman,Taroh Kinoshita,David A. Dyment,Kym M. Boycott,Philippe M. Campeau, Human Molecular Genetics, OXFORD UNIV PRESS, Vol. 26, No. 9, p. 1706-1715, 2017/05/01
  • Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders, Alistair T. Pagnamenta,Yoshiko Murakami,John M. Taylor,Consuelo Anzilotti,Malcolm F. Howard,Venessa Miller,Diana S. Johnson,Shereen Tadros,Sahar Mansour,I. Karen Temple,Rachel Firth,Elisabeth Rosser,Rachel E. Harrison,Bronwen Kerr,Niko Popitsch,Taroh Kinoshita,Jenny C. Taylor,Usha Kini, European Journal of Human Genetics, NATURE PUBLISHING GROUP, Vol. 25, No. 6, p. 669-679, 2017/03/22
  • Mutations in the phosphatidylinositol glycan C (PIGC) gene are associated with epilepsy and intellectual disability, Simon Edvardson,Yoshiko Murakami,Thi Tuyet Mai Nguyen,Maher Shahrour,Anik St-Denis,Avraham Shaag,Nadira Damseh,Françoise Le Deist,Yenan Bryceson,Bassam Abu-Libdeh,Philippe M Campeau,Taroh Kinoshita,Orly Elpeleg, Journal of Medical Genetics, BMJ PUBLISHING GROUP, Vol. 54, No. 3, p. 196-201, 2017/03/01
  • Glycan region of GPI anchored-protein is required for cytocidal oligomerization of an anticancer parasporin-2, Cry46Aa1 protein, from Bacillus thuringiensis strain A1547, Yuich Abe,Hiroshi Inoue,Hisashi Ashida,Yusuke Maeda,Taroh Kinoshita,Sakae Kitada, Journal of Invertebrate Pathology, Academic Press Inc., Vol. 142, p. 71-81, 2017/01/01
  • A homozygous PIGN missense mutation in Soft-Coated Wheaten Terriers with a canine paroxysmal dyskinesia, Ana L. Kolicheski,Gary S. Johnson,Tendai Mhlanga-Mutangadura,Jeremy F. Taylor,Robert D. Schnabel,Taroh Kinoshita,Yoshiko Murakami,Dennis P. O’Brien, Neurogenetics, SPRINGER, Vol. 18, No. 1, p. 39-47, 2017/01/01
  • PIGN prevents protein aggregation in the endoplasmic reticulum independently of its function in the GPI synthesis, Shinji Ihara,Sohei Nakayama,Yoshiko Murakami,Emiko Suzuki,Masayo Asakawa,Taroh Kinoshita,Hitoshi Sawa, Journal of Cell Science, COMPANY OF BIOLOGISTS LTD, Vol. 130, No. 3, p. 602-613, 2017
  • A novel mutation in PIGW causes glycosylphosphatidylinositol deficiency without hyperphosphatasia, Max Hogrebe,Yoshiko Murakami,Martin Wild,Martina Ahlmann,Saskia Biskup,Konstanze Hörtnagel,Marianne Grüneberg,Janine Reunert,Tobias Linden,Taroh Kinoshita,Thorsten Marquardt, American Journal of Medical Genetics, Part A, WILEY-BLACKWELL, Vol. 170, No. 12, p. 3319-3322, 2016/12/01
  • Interim analysis of post-marketing surveillance of eculizumab for paroxysmal nocturnal hemoglobinuria in Japan, Haruhiko Ninomiya,Naoshi Obara,Shigeru Chiba,Kensuke Usuki,Kaichi Nishiwaki,Itaru Matsumura,Tsutomu Shichishima,Shinichiro Okamoto,Jun ichi Nishimura,Kazuma Ohyashiki,Shinji Nakao,Kiyoshi Ando,Yoshinobu Kanda,Tatsuya Kawaguchi,Hideki Nakakuma,Daisuke Harada,Hirozumi Akiyama,Taroh Kinoshita,Keiya Ozawa,Mitsuhiro Omine,Yuzuru Kanakura, International Journal of Hematology, Vol. 104, No. 5, p. 548-558, 2016/11/01
  • Lipoarabinomannan binding to lactosylceramide in lipid rafts is essential for the phagocytosis of mycobacteria by human neutrophils, Hitoshi Nakayama,Hidetake Kurihara,Yasu S. Morita,Taroh Kinoshita,Laura Mauri,Alessandro Prinetti,Sandro Sonnino,Noriko Yokoyama,Hideoki Ogawa,Kenji Takamori,Kazuhisa Iwabuchi, Science Signaling, American Association for the Advancement of Science, Vol. 9, No. 449, 2016/10/11
  • 3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport, Masamichi Nagae,Tetsuya Hirata,Kana Morita-Matsumoto,Romina Theiler,Morihisa Fujita,Taroh Kinoshita,Yoshiki Yamaguchi, Journal of Molecular Biology, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 428, No. 20, p. 4087-4099, 2016/10/09
  • Rare Noncoding Mutations Extend the Mutational Spectrum in the PGAP3 Subtype of Hyperphosphatasia with Mental Retardation Syndrome, Alexej Knaus,Tomonari Awaya,Ingo Helbig,Zaid Afawi,Manuela Pendziwiat,Jubran Abu-Rachma,Miles D. Thompson,David E. Cole,Steve Skinner,Fran Annese,Natalie Canham,Michal R. Schweiger,Peter N. Robinson,Stefan Mundlos,Taroh Kinoshita,Arnold Munnich,Yoshiko Murakami,Denise Horn,Peter M. Krawitz, Human Mutation, WILEY-BLACKWELL, Vol. 37, No. 8, p. 737-744, 2016/08/01
  • Spatially distinct and metabolically active membrane domain in mycobacteria, Jennifer M. Hayashi,Chu Yuan Luo,Jacob A. Mayfield,Tsungda Hsu,Takeshi Fukuda,Andrew L. Walfield,Samantha R. Giffen,John D. Leszyk,Christina E. Baer,Owen T. Bennion,Ashoka Madduri,Scott A. Shaffer,Bree B. Aldridge,Christopher M. Sassetti,Steven J. Sandler,Taroh Kinoshita,D. Branch Moody,Yasu S. Morita, Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, Vol. 113, No. 19, p. 5400-5405, 2016/05/10
  • Pathogenic Variants in PIGG Cause Intellectual Disability with Seizures and Hypotonia, Periklis Makrythanasis,Mitsuhiro Kato,Maha S. Zaki,Hirotomo Saitsu,Kazuyuki Nakamura,Federico A. Santoni,Satoko Miyatake,Mitsuko Nakashima,Mahmoud Y. Issa,Michel Guipponi,Audrey Letourneau,Clare V. Logan,Nicola Roberts,David A. Parry,Colin A. Johnson,Naomichi Matsumoto,Hanan Hamamy,Eamonn Sheridan,Taroh Kinoshita,Stylianos E. Antonarakis,Yoshiko Murakami, American Journal of Human Genetics, Cell Press, Vol. 98, No. 4, p. 615-626, 2016/04
  • A novel PIGN mutation and prenatal diagnosis of inherited glycosylphosphatidylinositol deficiency, Taku Nakagawa,Mariko Taniguchi-Ikeda,Yoshiko Murakami,Shota Nakamura,Daisuke Motooka,Tomomi Emoto,Wataru Satake,Masahiro Nishiyama,Daisaku Toyoshima,Naoya Morisada,Satoshi Takada,Shinya Tairaku,Nobuhiko Okamoto,Ichiro Morioka,Hiroki Kurahashi,Tatsushi Toda,Taroh Kinoshita,Kazumoto Iijima, American Journal of Medical Genetics, Part A, Wiley-Liss Inc., Vol. 170, No. 1, p. 183-188, 2016/01/01
  • A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO, Gun Hee Lee,Morihisa Fujita,Katsuyoshi Takaoka,Yoshiko Murakami,Yoshitaka Fujihara,Noriyuki Kanzawa,Kei Ichi Murakami,Eriko Kajikawa,Yoko Takada,Kazunobu Saito,Masahito Ikawa,Hiroshi Hamada,Yusuke Maeda,Taroh Kinoshita, Journal of Cell Biology, Vol. 215, No. 5, p. 705-718, 2016
  • Symbol nomenclature for graphical representations of glycans, Ajit Varki,Richard D. Cummings,Markus Aebi,Nicole H. Packer,Peter H. Seeberger,Jeffrey D. Esko,Pamela Stanley,Gerald Hart,Alan Darvill,Taroh Kinoshita,James J. Prestegard,Ronald L. Schnaar,Hudson H. Freeze,Jamey D. Marth,Carolyn R. Bertozzi,Marilynn E. Etzler,Martin Frank,Johannes F.G. Vliegenthart,Thomas Lütteke,Serge Perez,Evan Bolton,Pauline Rudd,James Paulson,Minoru Kanehisa,Philip Toukach,Kiyoko F. Aoki-Kinoshita,Anne Dell,Hisashi Narimatsu,William York,Naoyuki Taniguchi,Stuart Kornfeld, Glycobiology, Oxford University Press, Vol. 25, No. 12, p. 1323-1324, 2015/12/01
  • Cerebral visual impairment and intellectual disability caused by PGAP1 variants, Daniëlle G.M. Bosch,F. Nienke Boonstra,Taroh Kinoshita,Shalini Jhangiani,Joep De Ligt,Frans P.M. Cremers,James R. Lupski,Yoshiko Murakami,Bert B.A. De Vries, European Journal of Human Genetics, NATURE PUBLISHING GROUP, Vol. 23, No. 12, p. 1689-1693, 2015/12/01
  • Mutations in PIGY: Expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies, Biljana Ilkovski,Alistair T. Pagnamenta,Gina L. O'Grady,Taroh Kinoshita,Malcolm F. Howard,Monkol Lek,Brett Thomas,Anne Turner,John Christodoulou,David Sillence,Samantha J.L. Knight,Niko Popitsch,David A. Keays,Consuelo Anzilotti,Anne Goriely,Leigh B. Waddel,Fabienne Brilot,Kathryn N. North,Noriyuki Kanzawa,Daniel G. Macarthur,Jenny C. Taylor,Usha Kini,Yoshiko Murakami,Nigel F. Clarke, Human Molecular Genetics, OXFORD UNIV PRESS, Vol. 24, No. 21, p. 6146-6159, 2015/11/01
  • Genome-wide screening of genes required for glycosylphosphatidylinositol biosynthesis, Yao Rong,Shota Nakamura,Tetsuya Hirata,Daisuke Motooka,Yi Shi Liu,Zeng An He,Xiao Dong Gao,Yusuke Maeda,Taroh Kinoshita,Morihisa Fujita, PLoS ONE, Public Library of Science, Vol. 10, No. 9, 2015/09/18
  • Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport, Tetsuya Hirata,Morihisa Fujita,Shota Nakamura,Kazuyoshi Gotoh,Daisuke Motooka,Yoshiko Murakami,Yusuke Maeda,Taroh Kinoshita, Molecular Biology of the Cell, American Society for Cell Biology, Vol. 26, No. 17, p. 3071-3084, 2015/09/01
  • Inherited GPI deficiency; a new disease with intellectual disability and epilepsy, Yoshiko Murakami,Taroh Kinoshita, Nihon rinsho. Japanese journal of clinical medicine, Vol. 73, No. 7, p. 1227-1237, 2015/07/01
  • Mutations in PIGL in a patient with Mabry syndrome, Ikuma Fujiwara,Yoshiko Murakami,Tetsuya Niihori,Junko Kanno,Akiko Hakoda,Osamu Sakamoto,Nobuhiko Okamoto,Ryo Funayama,Takeshi Nagashima,Keiko Nakayama,Taroh Kinoshita,Shigeo Kure,Yoichi Matsubara,Yoko Aoki, American Journal of Medical Genetics, Part A, Vol. 167, No. 4, p. 777-785, 2015/04
  • Congenital Disorders of Glycosylation: Glycosylphosphatidylinositol (gpi)-Related, Yoshiko Murakami,Taroh Kinoshita, Glycoscience: Biology and Medicine, Springer Japan, p. 1229-1236, 2015/01/01
  • Inherited GPI deficiencies: A new disease with intellectual disability and epilepsy, Yoshiko Murakami,Taroh Kinoshita, No To Hattatsu, Japanese Society of Child Neurology, Vol. 47, No. 1, p. 5-13, 2015/01/01
  • Structural changes of GPI anchor after its attachment to proteins: Functional significance, Taroh Kinoshita, Advances in Experimental Medicine and Biology, Springer New York LLC, Vol. 842, p. 17-25, 2015
  • 遺伝性血管性浮腫(HAE)ガイドライン 改訂2014年版, 堀内 孝彦,大澤 勲,岡田 秀親,塚本 浩,中尾 実樹,木下 タロウ,高橋 実,野中 勝,松下 操,関根 英治,山本 哲郎,若宮 伸隆,藤田 禎三,瀬谷 司,井上 徳光,大井 洋之,一般社団法人日本補体学会HAEガイドライン作成委員会, 補体, (一社)日本補体学会, Vol. 51, No. 2, p. 24-30, 2014/12
  • Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells, Masahiro Tokunaga,Chikara Kokubu,Yusuke Maeda,Jun Sese,Kyoji Horie,Nakaba Sugimoto,Taroh Kinoshita,Kosuke Yusa,Junji Takeda, BMC Genomics, BioMed Central Ltd., Vol. 15, No. 1, 2014/11/24
  • Endosomes-to-TGN retrograde transport mediated by GARP is required for post-Golgi anterograde transport and glycosylation, Tetsuya Hirata,Morihisa Fujita,Shota Nakamura,Kazuyoshi Gotoh,Daisuke Motooka,Yoshiko Murakami,Yusuke Maeda,Taroh Kinoshita, 2014/11
  • New insights into the functions of PIGF, a protein involved in the ethanolamine phosphate transfer steps of glycosylphosphatidylinositol biosynthesis, Matthew J. Stokes,Yoshiko Murakami,Yusuke Maeda,Taroh Kinoshita,Yasu S. Morita, Biochemical Journal, PORTLAND PRESS LTD, Vol. 463, No. 2, p. 249-256, 2014/10/15
  • Novel compound heterozygous PIGT mutations caused multiple congenital anomalies-hypotonia-seizures syndrome 3, Mitsuko Nakashima,Hirofumi Kashii,Yoshiko Murakami,Mitsuhiro Kato,Yoshinori Tsurusaki,Noriko Miyake,Masaya Kubota,Taroh Kinoshita,Hirotomo Saitsu,Naomichi Matsumoto, Neurogenetics, SPRINGER, Vol. 15, No. 3, p. 193-200, 2014/08
  • Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis, Hilary C. Martin,Grace E. Kim,Alistair T. Pagnamenta,Yoshiko Murakami,Gemma L. Carvill,Esther Meyer,Richard R. Copley,Andrew Rimmer,Giulia Barcia,Matthew R. Fleming,Jack Kronengold,Maile R. Brown,Karl A. Hudspith,John Broxholme,Alexander Kanapin,Jean Baptiste Cazier,Taroh Kinoshita,Rima Nabbout,David Bentley,Gil McVean,Sinéad Heavin,Zenobia Zaiwalla,Tony McShane,Heather C. Mefford,Deborah Shears,Helen Stewart,Manju A. Kurian,Ingrid E. Scheffer,Edward Blair,Peter Donnelly,Leonard K. Kaczmarek,Jenny C. Taylor, Human Molecular Genetics, OXFORD UNIV PRESS, Vol. 23, No. 12, p. 3200-3211, 2014/06/15
  • The α-helical region in p24γ<inf>2</inf> subunit of p24 protein cargo receptor is pivotal for the recognition and transport of glycosylphosphatidylinositol-anchored proteins, Romina Theiler,Morihisa Fujita,Masamichi Nagae,Yoshiki Yamaguchi,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 289, No. 24, p. 16835-16843, 2014/06/13
  • PIGA mutations cause early-onset epileptic encephalopathies and distinctive features, Mitsuhiro Kato,Hirotomo Saitsu,Yoshiko Murakami,Kenjiro Kikuchi,Shuei Watanabe,Mizue Iai,Kazushi Miya,Ryuki Matsuura,Rumiko Takayama,Chihiro Ohba,Mitsuko Nakashima,Yoshinori Tsurusaki,Noriko Miyake,Shin Ichiro Hamano,Hitoshi Osaka,Kiyoshi Hayasaka,Taroh Kinoshita,Naomichi Matsumoto, Neurology, LIPPINCOTT WILLIAMS & WILKINS, Vol. 82, No. 18, p. 1587-1596, 2014/05/06
  • Erratum to: PIGN mutations cause congenital anomalies, developmental delay, hypotonia, epilepsy, and progressive cerebellar atrophy (neurogenetics, DOI:10.1007/s10048-013-0384-7), Chihiro Ohba,Nobuhiko Okamoto,Yoshiko Murakami,Yasuhiro Suzuki,Yoshinori Tsurusaki,Mitsuko Nakashima,Noriko Miyake,Fumiaki Tanaka,Taroh Kinoshita,Naomichi Matsumoto,Hirotomo Saitsu, Neurogenetics, Springer Verlag, Vol. 15, No. 2, 2014/05/01
  • Paroxysmal nocturnal hemoglobinuria with copy number-neutral 6pLOH in GPI (+) but not in GPI (-) granulocytes, Yasutaka Ueda,Jun Ichi Nishimura,Yoshiko Murakami,Sachiko Kajigaya,Taroh Kinoshita,Yuzuru Kanakura,Neal S. Young, European Journal of Haematology, WILEY-BLACKWELL, Vol. 92, No. 5, p. 450-453, 2014/05
  • Null Mutation in PGAP1 Impairing Gpi-Anchor Maturation in Patients with Intellectual Disability and Encephalopathy, Yoshiko Murakami,Hasan Tawamie,Yusuke Maeda,Christian Büttner,Rebecca Buchert,Farah Radwan,Stefanie Schaffer,Heinrich Sticht,Michael Aigner,André Reis,Taroh Kinoshita,Rami Abou Jamra, PLoS Genetics, PUBLIC LIBRARY SCIENCE, Vol. 10, No. 5, 2014/05
  • PIGN mutations cause congenital anomalies, developmental delay, hypotonia, epilepsy, and progressive cerebellar atrophy, Chihiro Ohba,Nobuhiko Okamoto,Yoshiko Murakami,Yasuhiro Suzuki,Yoshinori Tsurusaki,Mitsuko Nakashima,Noriko Miyake,Fumiaki Tanaka,Taroh Kinoshita,Naomichi Matsumoto,Hirotomo Saitsu, Neurogenetics, SPRINGER, Vol. 15, No. 2, p. 85-92, 2014/05
  • Mutations in PGAP3 impair GPI-anchor maturation, causing a subtype of hyperphosphatasia with mental retardation, Malcolm F. Howard,Yoshiko Murakami,Alistair T. Pagnamenta,Cornelia Daumer-Haas,Björn Fischer,Jochen Hecht,David A. Keays,Samantha J.L. Knight,Uwe Kölsch,Ulrike Krüger,Steffen Leiz,Yusuke Maeda,Daphne Mitchell,Stefan Mundlos,John A. Phillips,Peter N. Robinson,Usha Kini,Jenny C. Taylor,Denise Horn,Taroh Kinoshita,Peter M. Krawitz, American Journal of Human Genetics, CELL PRESS, Vol. 94, No. 2, p. 278-287, 2014/02/06
  • PIGO mutations in intractable epilepsy and severe developmental delay with mild elevation of alkaline phosphatase levels, Kazuyuki Nakamura,Hitoshi Osaka,Yoshiko Murakami,Rie Anzai,Kiyomi Nishiyama,Hirofumi Kodera,Mitsuko Nakashima,Yoshinori Tsurusaki,Noriko Miyake,Taroh Kinoshita,Naomichi Matsumoto,Hirotomo Saitsu, Epilepsia, WILEY-BLACKWELL, Vol. 55, No. 2, p. E13-E17, 2014/02
  • GPI mannose extension (PIGM, PIGV, PIGB, PIGZ), Taroh Kinoshita,Norimitsu Inoue, Handbook of Glycosyltransferases and Related Genes, Second Edition, Springer Japan, Vol. 2, p. 1209-1220, 2014/01/01
  • Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GlcNAc transferase): A complex comprised of PIGA, PIGC, PIGH, PIGQ, PIGP, PIGY and DPM2, Taroh Kinoshita,Norimitsu Inoue,Yoshiko Murakami, Handbook of Glycosyltransferases and Related Genes, Second Edition, Springer Japan, Vol. 2, p. 1193-1208, 2014/01/01
  • Genetic variants in C5 and poor response to eculizumab, Jun Ichi Nishimura,Masaki Yamamoto,Shin Hayashi,Kazuma Ohyashiki,Kiyoshi Ando,Andres L. Brodsky,Hideyoshi Noji,Kunio Kitamura,Tetsuya Eto,Toru Takahashi,Masayoshi Masuko,Takuro Matsumoto,Yuji Wano,Tsutomu Shichishima,Hirohiko Shibayama,Masakazu Hase,Lan Li,Krista Johnson,Alberto Lazarowski,Paul Tamburini,Johji Inazawa,Taroh Kinoshita,Yuzuru Kanakura, New England Journal of Medicine, MASSACHUSETTS MEDICAL SOC, Vol. 370, No. 7, p. 632-639, 2014
  • Glycosylphosphatidylinositol (GPI) anchor deficiency caused by mutations in PIGW is associated with West syndrome and hyperphosphatasia with mental retardation syndrome, Tomohiro Chiyonobu,Norimitsu Inoue,Masafumi Morimoto,Taroh Kinoshita,Yoshiko Murakami, Journal of Medical Genetics, Vol. 51, No. 3, p. 203-207, 2014
  • Vitamin B6-responsive epilepsy due to inherited GPI deficiencyichiro, Ichiro Kuki,Yukitoshi Takahashi,Shin Okazaki,Hisashi Kawawaki,Eiji Ehara,Norimitsu Inoue,Taroh Kinoshita,Yoshiko Murakami, Neurology, Vol. 81, No. 16, p. 1467-1469, 2013/10/15
  • Long-term efficacy and safety of eculizumab in Japanese patients with PNH: AEGIS trial, Yuzuru Kanakura,Kazuma Ohyashiki,Tsutomu Shichishima,Shinichiro Okamoto,Kiyoshi Ando,Haruhiko Ninomiya,Tatsuya Kawaguchi,Shinji Nakao,Hideki Nakakuma,Jun Ichi Nishimura,Taroh Kinoshita,Camille L. Bedrosian,Keiya Ozawa,Mitsuhiro Omine, International Journal of Hematology, Vol. 98, No. 4, p. 406-416, 2013/10
  • Glycosylphosphatidylinositol mannosyltransferase II is the rate-limiting enzyme in glycosylphosphatidylinositol biosynthesis under limited dolichol-phosphate mannose availability, Tetsuya Hirata,Morihisa Fujita,Noriyuki Kanzawa,Yoshiko Murakami,Yusuke Maeda,Taroh Kinoshita, Journal of Biochemistry, Vol. 154, No. 3, p. 257-264, 2013/09
  • Significance of glycosylphosphatidylinositol-anchored protein enrichment in lipid rafts for the control of autoimmunity, Yetao Wang,Yoshiko Murakami,Teruhito Yasui,Shigeharu Wakana,Hitoshi Kikutani,Taroh Kinoshita,Yusuke Maeda, Journal of Biological Chemistry, Vol. 288, No. 35, p. 25490-25499, 2013/08/30
  • A case of paroxysmal nocturnal hemoglobinuria caused by a germline mutation and a somatic mutation in PIGT, Peter M. Krawitz,Britta Höchsmann,Yoshiko Murakami,Britta Teubner,Ulrike Krüger,Eva Klopocki,Heidemarie Neitzel,Alexander Hoellein,Christina Schneider,Dmitri Parkhomchuk,Jochen Hecht,Peter N. Robinson,Stefan Mundlos,Taroh Kinoshita,Hubert Schrezenmeier, Blood, American Society of Hematology, Vol. 122, No. 7, p. 1312-1315, 2013/08/15
  • C5遺伝子多型によるPNH治療薬エクリズマブに対する不応性の解析, 西村 純一,山本 正樹,大屋敷 一馬,安藤 潔,長谷 昌知,柴山 浩彦,稲澤 譲治,木下 タロウ,金倉 譲, 補体シンポジウム講演集, (一社)日本補体学会, Vol. 50, p. 44-45, 2013/07
  • Implications of lipid moiety in oligomerization and immunoreactivities of GPI-Anchored proteins, Jihyoun Seong,Yetao Wang,Taroh Kinoshita,Yusuke Maeda, Journal of Lipid Research, Vol. 54, No. 4, p. 1077-1091, 2013/04
  • PGAP2 mutations, affecting the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation syndrome, Peter M. Krawitz,Yoshiko Murakami,Angelika Rieß,Marja Hietala,Ulrike Krüger,Na Zhu,Taroh Kinoshita,Stefan Mundlos,Jochen Hecht,Peter N. Robinson,Denise Horn, American Journal of Human Genetics, CELL PRESS, Vol. 92, No. 4, p. 584-589, 2013/04
  • Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability, Lars Hansen,Hasan Tawamie,Yoshiko Murakami,Yuan Mang,Shoaib Ur Rehman,Rebecca Buchert,Stefanie Schaffer,Safia Muhammad,Mads Bak,Markus M. Nöthen,Eric P. Bennett,Yusuke Maeda,Michael Aigner,André Reis,Taroh Kinoshita,Niels Tommerup,Shahid Mahmood Baig,Rami Abou Jamra, American Journal of Human Genetics, Vol. 92, No. 4, p. 575-583, 2013/04
  • 本邦固有のC5遺伝子多型によるPNH治療薬エクリズマブに対する不応性, 山本 正樹,西村 純一,大屋敷 一馬,安藤 潔,長谷 昌知,柴山 浩彦,稲澤 譲治,木下 タロウ,金倉 譲, 日本内科学会雑誌, (一社)日本内科学会, Vol. 102, No. Suppl., p. 185-185, 2013/02
  • Occupancy of whole blood cells by a single PIGA-mutant clone with HMGA2 amplification in a paroxysmal nocturnal haemoglobinuria patient having blood cells with NKG2D ligands, Nobuyoshi Hanaoka,Yoshiko Murakami,Masahide Nagata,Kentaro Horikawa,Shoichi Nagakura,Yuji Yonemura,Shogo Murata,Takashi Sonoki,Taroh Kinoshita,Hideki Nakakuma, British Journal of Haematology, Vol. 160, No. 1, p. 114-116, 2013/01
  • Critical roles for lipomannan and lipoarabinomannan in cell wall integrity of mycobacteria and pathogenesis of tuberculosis, Takeshi Fukuda,Takayuki Matsumura,Manabu Ato,Maho Hamasaki,Yukiko Nishiuchi,Yoshiko Murakami,Yusuke Maeda,Tamotsu Yoshimori,Sohkichi Matsumoto,Kazuo Kobayashi,Taroh Kinoshita,Yasu S. Morita, mBio, Vol. 4, No. 1, p. e00472-e00412, 2013
  • Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels, Ursula Loizides-Mangold,Fabrice P.A. David,Victor J. Nesatyy,Taroh Kinoshita,Howard Riezman, Journal of Lipid Research, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 53, No. 8, p. 1522-1534, 2012/08
  • GPHR-dependent functions of the golgi apparatus are essential for the formation of lamellar granules and the skin barrier, Masahito Tarutani,Kimiko Nakajima,Yoshikazu Uchida,Mikiro Takaishi,Naoko Goto-Inoue,Masahito Ikawa,Mitsutoshi Setou,Taroh Kinoshita,Peter M. Elias,Shigetoshi Sano,Yusuke Maeda, Journal of Investigative Dermatology, Nature Publishing Group, Vol. 132, No. 8, p. 2019-2025, 2012/08
  • Mutations in PIGO, a member of the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation, Peter M. Krawitz,Yoshiko Murakami,Jochen Hecht,Ulrike Krüger,Susan E. Holder,Geert R. Mortier,Barbara Delle Chiaie,Elfride De Baere,Miles D. Thompson,Tony Roscioli,Szymon Kielbasa,Taroh Kinoshita,Stefan Mundlos,Peter N. Robinson,Denise Horn, American Journal of Human Genetics, CELL PRESS, Vol. 91, No. 1, p. 146-151, 2012/07/13
  • Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome,and rhizomelic chondrodysplasia punctata, Noriyuki Kanzawa,Nobuyuki Shimozawa,Ronald J.A. Wanders,Kazutaka Ikeda,Yoshiko Murakami,Hans R. Waterham,Satoru Mukai,Morihisa Fujita,Yusuke Maeda,Ryo Taguchi,Yukio Fujiki,Taroh Kinoshita, Journal of Lipid Research, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 53, No. 4, p. 653-663, 2012/04
  • Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia mental retardation syndrome, Yoshiko Murakami,Noriyuki Kanzawa,Kazunobu Saito,Peter M. Krawitz,Stefan Mundlos,Peter N. Robinson,Anastasios Karadimitris,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, Vol. 287, No. 9, p. 6318-6325, 2012/02/24
  • Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria, Yoshiko Murakami,Norimitsu Inoue,Tsutomu Shichishima,Rieko Ohta,Hideyoshi Noji,Yusuke Maeda,Jun ichi Nishimura,Yuzuru Kanakura,Taroh Kinoshita, British Journal of Haematology, Vol. 156, No. 3, p. 383-387, 2012/02
  • Enhanced response of T lymphocytes from Pgap3 knockout mouse: Insight into roles of fatty acid remodeling of GPI anchored proteins, Hidekazu Murakami,Yetao Wang,Hidetoshi Hasuwa,Yusuke Maeda,Taroh Kinoshita,Yoshiko Murakami, Biochemical and Biophysical Research Communications, Vol. 417, No. 4, p. 1235-1241, 2012/01/27
  • Identification of a second catalytically active trans-sialidase in Trypanosoma brucei, Fumiki Nakatani,Yasu S. Morita,Hisashi Ashida,Kisaburo Nagamune,Yusuke Maeda,Taroh Kinoshita, Biochemical and Biophysical Research Communications, Vol. 415, No. 2, p. 421-425, 2011/11/18
  • Impaired FcεRI stability, signaling, and effector functions in murine mast cells lacking glycosylphosphatidylinositol-anchored proteins, Wouter L.W. Hazenbos,Ping Wu,Jeffrey Eastham-Anderson,Taroh Kinoshita,Eric J. Brown, Blood, AMER SOC HEMATOLOGY, Vol. 118, No. 16, p. 4377-4383, 2011/10/20
  • Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI, Morihisa Fujita,Reika Watanabe,Nina Jaensch,Maria Romanova-Michaelides,Tadashi Satoh,Masaki Kato,Howard Riezman,Yoshiki Yamaguchi,Yusuke Maeda,Taroh Kinoshita, Journal of Cell Biology, Vol. 194, No. 1, p. 61-75, 2011/07/11
  • Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: The AEGIS Clinical Trial, Yuzuru Kanakura,Kazuma Ohyashiki,Tsutomu Shichishima,Shinichiro Okamoto,Kiyoshi Ando,Haruhiko Ninomiya,Tatsuya Kawaguchi,Shinji Nakao,Hideki Nakakuma,Jun Ichi Nishimura,Taroh Kinoshita,Camille L. Bedrosian,Marye Ellen Valentine,Gus Khursigara,Keiya Ozawa,Mitsuhiro Omine, International Journal of Hematology, Vol. 93, No. 1, p. 36-46, 2011/01
  • Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome, Peter M. Krawitz,Michal R. Schweiger,Christian Rödelsperger,Carlo Marcelis,Uwe Kölsch,Christian Meisel,Friederike Stephani,Taroh Kinoshita,Yoshiko Murakami,Sebastian Bauer,Melanie Isau,Axel Fischer,Andreas Dahl,Martin Kerick,Jochen Hecht,Sebastian Köhler,Marten Jäger,Johannes Grünhagen,Birgit Jonske De Condor,Sandra Doelken,Han G. Brunner,Peter Meinecke,Eberhard Passarge,Miles D. Thompson,David E. Cole,Denise Horn,Tony Roscioli,Stefan Mundlos,Peter N. Robinson, Nature Genetics, NATURE PUBLISHING GROUP, Vol. 42, No. 10, p. 827-829, 2010/10
  • Stress-induced synthesis of phosphatidylinositol 3-phosphate in mycobacteria, Yasu S. Morita,Yoshiki Yamaryo-Botte,Kana Miyanagi,Judy M. Callaghan,John H. Patterson,Paul K. Crellin,Ross L. Coppel,Helen Billman-Jacobe,Taroh Kinoshita,Malcolm J. McConville, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 285, No. 22, p. 16643-16650, 2010/05/28
  • Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish rohon-beard neurons to respond to mechanosensory stimulation, Yuri Nakano,Morihisa Fujita,Kazutoyo Ogino,Louis Saint-Amant,Taroh Kinoshita,Yoichi Oda,Hiromi Hirata, Development, Vol. 137, No. 10, p. 1689-1698, 2010/05/15
  • Acquisition of complement resistance through incorporation of CD55/decay-accelerating factor into viral particles bearing baculovirus GP64, Yuuki Kaname,Hideki Tani,Chikako Kataoka,Mai Shiokawa,Shuhei Taguwa,Takayuki Abe,Kohji Moriishi,Taroh Kinoshita,Yoshiharu Matsuura, Journal of Virology, Vol. 84, No. 7, p. 3210-3219, 2010/04
  • Controlled expression of branch-forming mannosyltransferase is critical for mycobacterial lipoarabinomannan biosynthesis, Chubert B.C. Sena,Takeshi Fukuda,Kana Miyanagi,Sohkichi Matsumoto,Kazuo Kobayashi,Yoshiko Murakami,Yusuke Maeda,Taroh Kinoshita,Yasu S. Morita, Journal of Biological Chemistry, Vol. 285, No. 18, p. 13326-13336, 2010/04
  • GPI-Anchor: Update for Biosynthesis and Remodeling, Yusuke Maeda,Morihisa Fujita,Taroh Kinoshita, Trends in Glycoscience and Glycotechnology, Vol. 22, No. 126, p. 182-193, 2010
  • The acidic environment of the golgi is critical for glycosylation and transport, Yusuke Maeda,Taroh Kinoshita, Methods in Enzymology, ELSEVIER ACADEMIC PRESS INC, Vol. 480, No. C, p. 495-510, 2010
  • Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle, Eri Ishikawa,Tetsuaki Ishikawa,Yasu S. Morita,Kenji Toyonaga,Hisakata Yamada,Osamu Takeuchi,Taroh Kinoshita,Shizuo Akira,Yasunobu Yoshikai,Sho Yamasaki, Journal of Experimental Medicine, ROCKEFELLER UNIV PRESS, Vol. 206, No. 13, p. 2879-2888, 2009/12/21
  • Peroxisome dependency of alkyl-containing GPI-anchor biosynthesis in the endoplasmic reticulum, Noriyuki Kanzawa,Yusuke Maeda,Hideo Ogiso,Yoshiko Murakami,Ryo Taguchi,Taroh Kinoshita, Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 42, p. 17711-17716, 2009/10/20
  • GPI Glycan Remodeling by PGAP5 Regulates Transport of GPI-Anchored Proteins from the ER to the Golgi, Morihisa Fujita,Yusuke Maeda,Moonjin Ra,Yoshiki Yamaguchi,Ryo Taguchi,Taroh Kinoshita, Cell, Vol. 139, No. 2, p. 352-365, 2009/10/16
  • Enhanced humoral immune responses against T-independent antigens in Fcα/μR-deficient mice, Shin Ichiro Honda,Naoki Kurita,Akitomo Miyamoto,Yukiko Cho,Kenta Usui,Kie Takeshita,Satoru Takahashi,Teruhito Yasui,Hitoshi Kikutani,Taroh Kinoshita,Teizo Fujita,Satoko Tahara-Hanaoka,Kazuko Shibuya,Akira Shibuya, Proceedings of the National Academy of Sciences of the United States of America, NATL ACAD SCIENCES, Vol. 106, No. 27, p. 11230-11235, 2009/07/07
  • [Host-pathogen interactions: parasites]., Taroh Kinoshita, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 54, No. 8 Suppl, p. 1027-1028, 2009/06
  • Testicular angiotensin-converting enzyme with different glycan modification: Characterization on glycosylphosphatidylinositol-anchored protein releasing and dipeptidase activities, Gen Kondoh,Hitomi Watanabe,Yuko Tashima,Yusuke Maeda,Taroh Kinoshita, Journal of Biochemistry, OXFORD UNIV PRESS, Vol. 145, No. 1, p. 115-121, 2009/01
  • Integrin-linked kinase associated with integrin activation, Shigenori Honda,Hiroko Shirotani-Ikejima,Seiji Tadokoro,Yusuke Maeda,Taroh Kinoshita,Yoshiaki Tomiyama,Toshiyuki Miyata, Blood, AMER SOC HEMATOLOGY, Vol. 113, No. 21, p. 5304-5313, 2009
  • Efficacy of recombinant bacille Calmette-Guérin vaccine secreting interleukin-15/antigen 85B fusion protein in providing protection against Mycobacterium tuberculosis, Ce Tang,Hisakata Yamada,Kensuke Shibata,Naoyoshi Maeda,Shinichi Yoshida,Worawidh Wajjwalku,Naoya Ohara,Takeshi Yamada,Taroh Kinoshita,Yasunobu Yoshikai, Journal of Infectious Diseases, Vol. 197, No. 9, p. 1263-1274, 2008/05/01
  • Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane, Satoshi Takida,Yusuke Maeda,Taroh Kinoshita, Biochemical Journal, PORTLAND PRESS LTD, Vol. 409, No. 2, p. 555-562, 2008/01/15
  • Association of dengue virus NS1 protein with lipid rafts, Sansanee Noisakran,Thanyaporn Dechtawewat,Panisadee Avirutnan,Taroh Kinoshita,Uamporn Siripanyaphinyo,Chunya Puttikhunt,Watchara Kasinrerk,Prida Malasit,Nopporn Sittisombut, Journal of General Virology, Vol. 89, No. 10, p. 2492-2500, 2008
  • GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus, Yusuke Maeda,Toru Ide,Masato Koike,Yasuo Uchiyama,Taroh Kinoshita, Nature Cell Biology, Vol. 10, No. 10, p. 1135-1145, 2008
  • PGAP1 knock-out mice show otocephaly and male infertility, Yasutaka Ueda,Ryo Yamaguchi,Masahito Ikawa,Masaru Okabe,Eiichi Morii,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 282, No. 42, p. 30373-30380, 2007/10/19
  • Changes in molecular species profiles of glycosylphosphatidylinositol anchor precursors in early stages of biosynthesis, Toshiaki Houjou,Jun Hayakawa,Reika Watanabe,Yuko Tashima,Yusuke Maeda,Taroh Kinoshita,Ryo Taguchi, Journal of Lipid Research, Vol. 48, No. 7, p. 1599-1606, 2007/07
  • Both mammalian PIG-M and PIG-X are required for growth of GPI14-disrupted yeast, Youn Uck Kim,Hisashi Ashida,Kenichiro Mori,Yusuke Maeda,Yeongjin Hong,Taroh Kinoshita, Journal of Biochemistry, OXFORD UNIV PRESS, Vol. 142, No. 1, p. 123-129, 2007/07
  • Glycolipids with nonreducing end α-mannosyl residues that have the potential to activate invariant Vα19 NKT cells, Michio Shimamura,Yi Ying Huang,Naoki Okamoto,Yutaka Watanabe,Yoshiko Murakami,Taroh Kinoshita,Yoshio Hirabayashi,Chikara Murakata,Yukishige Ito,Tomoya Ogawa, FEBS Journal, BLACKWELL PUBLISHING, Vol. 274, No. 11, p. 2921-2932, 2007/06
  • Fatty acid remodeling of GPI-anchored proteins is required for their raft association, Yusuke Maeda,Yuko Tashima,Toshiaki Houjou,Morihisa Fujita,Takehiko Yoko-o,Yoshifumi Jigami,Ryo Taguchi,Taroh Kinoshita, Molecular Biology of the Cell, AMER SOC CELL BIOLOGY, Vol. 18, No. 4, p. 1497-1506, 2007/04
  • Targeted therapy for inherited GPI deficiency, Antonio M. Almeida,Yoshiko Murakami,Alastair Baker,Yusuke Maeda,Irene A.G. Roberts,Taroh Kinoshita,D. Mark Layton,Anastasios Karadimitris, New England Journal of Medicine, Massachussetts Medical Society, Vol. 356, No. 16, p. 1641-1647, 2007/04
  • Diseases Associated with GPI Anchors, T. Kinoshita,Y. Murakami,Y. S. Morita, Comprehensive Glycoscience: From Chemistry to Systems Biology, Elsevier, Vol. 4-4, p. 393-419, 2007/01/01
  • Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH), Norimitsu Inoue,Tomohisa Izui-Sarumaru,Yoshiko Murakami,Yuichi Endo,Jun Ichi Nishimura,Ken Kurokawa,Maki Kuwayama,Hiroaki Shime,Takashi Machii,Yuzuru Kanakura,Gabrielle Meyers,Carl Wittwer,Zhong Chen,William Babcock,Debra Frei-Lahr,Charles J. Parker,Taroh Kinoshita, Blood, Vol. 108, No. 13, p. 4232-4236, 2006/12/15
  • Isolation of new CHO cell mutants defective in CMP-sialic acid biosynthesis and transport, Dong Jun Shin,Ji Young Kang,Youn Uck Kim,Joong Sik Yoon,Hyon E. Choy,Yusuke Maeda,Taroh Kinoshita,Yeongjin Hong, Molecules and Cells, Vol. 22, No. 3, p. 343-352, 2006/12
  • PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria, Yasu S. Morita,Chubert B.C. Sena,Ross F. Waller,Ken Kurokawa,M. Fleur Sernee,Fumiki Nakatani,Ruth E. Haites,Helen Billman-Jacobe,Malcolm J. McConville,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 281, No. 35, p. 25143-25155, 2006/09/01
  • Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency, Antonio M. Almeida,Yoshiko Murakami,D. Mark Layton,Peter Hillmen,Gabrielle S. Sellick,Yusuke Maeda,Stephen Richards,Scott Patterson,Ioannis Kotsianidis,Luigina Mollica,Dorothy H. Crawford,Alastair Baker,Michael Ferguson,Irene Roberts,Richard Houlston,Taroh Kinoshita,Anastasios Karadimitris, Nature Medicine, NATURE PUBLISHING GROUP, Vol. 12, No. 7, p. 846-851, 2006/07
  • A cohort study of the nature of paroxysmal nocturnal hemoglobinuria clones and PIG-A mutations in patients with aplastic anemia, Wanchai Wanachiwanawin,Uamporn Siripanyaphinyo,Nattawan Piyawattanasakul,Taroh Kinoshita, European Journal of Haematology, Vol. 76, No. 6, p. 502-509, 2006/06
  • Removal or maintenance of inositol-linked acyl chain in glycosylphosphatidylinositol is critical in trypanosome life cycle, Yeonchul Hong,Kisaburo Nagamune,Yasu S. Morita,Fumiki Nakatani,Hisashi Ashida,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, 17, Vol. 281, No. 17, p. 11595-11602, 2006/04
  • PGAP2 is essential for correct processing and stable expression of GPI-anchored proteins, Yuko Tashima,Ryo Taguchi,Chie Murata,Hisashi Ashida,Taroh Kinoshita,Yusuke Maeda, Molecular Biology of the Cell, AMER SOC CELL BIOLOGY, Vol. 17, No. 3, p. 1410-1420, 2006/03
  • TbGPI16 is an essential component of GPI transamidase in Trypanosoma brucei, Yeonchul Hong,Kisaburo Nagamune,Kazuhito Ohishi,Yasu S. Morita,Hisashi Ashida,Yusuke Maeda,Taroh Kinoshita, FEBS Letters, Vol. 580, No. 2, p. 603-606, 2006/01/23
  • DPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3, Hisashi Ashida,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, 2, Vol. 281, No. 2, p. 896-904, 2006/01/13
  • Erratum: Kola acuminata proanthocyanidins: A class of anti-trypanosomal compounds effective against Trypanosoma brucei (International Journal for Parasitology (2005) 35 (91-103) DOI: 10.1016/j.ijpara.2004.10.019), B. K. Kubata,Kisaburo Nagamune,Nobutoshi Murakami,Patrick Merkel,Zakayi Kabututu,Samuel K. Martin,Taba M. Kalulu,Mostaqul Huq,Mitsuru Yoshida,Mayumi Ohnishi-Kameyama,Taroh Kinoshita,Michael Duszenko,Yoshihiro Urade, International Journal for Parasitology, Vol. 35, No. 14, 2005/12
  • The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component, Yoshiko Murakami,Uamporn Siripanyaphinyo,Yeongjin Hong,Yuko Tashima,Yusuke Maeda,Taroh Kinoshita, Molecular Biology of the Cell, Vol. 16, No. 11, p. 5236-5246, 2005/11
  • New mutant Chinese hamster ovary cell representing an unknown gene for attachment of glycosylphosphatidylinositol to proteins, Yeongjin Hong,Ji Young Kang,Youn Uck Kim,Dong Jun Shin,Hyon E. Choy,Yusuke Maeda,Taroh Kinoshita, Biochemical and Biophysical Research Communications, Vol. 335, No. 4, p. 1060-1069, 2005/10/07
  • Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system, Vincent W. Keng,Kojiro Yae,Tomoko Hayakawa,Sumi Mizuno,Yoshihiro Uno,Kosuke Yusa,Chikara Kokubu,Taroh Kinoshita,Keiko Akagi,Nancy A. Jenkins,Neal G. Copeland,Kyoji Horie,Junji Takeda, Nature Methods, Vol. 2, No. 10, p. 763-769, 2005/10
  • PIG-V involved in transferring the second mannose in glycosylphosphatidylinositol, Young Kang Ji,Yeongjin Hong,Hisashi Ashida,Nobue Shishioh,Yoshiko Murakami,Yasu S. Morita,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, 10, Vol. 280, No. 10, p. 9489-9497, 2005/03/11
  • GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol, Nobue Shishioh,Yeongjin Hong,Kazuhito Ohishi,Hisashi Ashida,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, 10, Vol. 280, No. 10, p. 9728-9734, 2005/03/11
  • Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I, Hisashi Ashida,Yeongjin Hong,Yoshiko Murakami,Nobue Shishioh,Nakaba Sugimoto,Youn Uck Kim,Yusuke Maeda,Taroh Kinoshita, Molecular Biology of the Cell, 3, Vol. 16, No. 3, p. 1439-1448, 2005/03
  • Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite, Thanaporn Rungruang,Osamu Kaneko,Yoshiko Murakami,Takafumi Tsuboi,Hiroshi Hamamoto,Nobuyoshi Akimitsu,Kazuhisa Sekimizu,Taroh Kinoshita,Motomi Torii, Molecular and Biochemical Parasitology, Elsevier, Vol. 140, No. 1, p. 13-21, 2005/03
  • Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization, Gen Kondoh,Hiromasa Tojo,Yuka Nakatani,Nobuyasu Komazawa,Chie Murata,Kazuo Yamagata,Yusuke Maeda,Taroh Kinoshita,Masaru Okabe,Ryo Taguchi,Junji Takeda, Nature Medicine, Vol. 11, No. 2, p. 160-166, 2005/02
  • Paroxysmal nocturnal hemoglobinuria, Mitsuhiro Omine,Taroh Kinoshita,Hideki Nakakuma,Jaroslaw P. Maciejewski,Charles J. Parker,Gérard Socié, International Journal of Hematology, Vol. 82, No. 5, p. 417-421, 2005
  • Kola acuminata proanthocyanidins: A class of anti-trypanosomal compounds effective against Trypanosoma brucei, B. K. Kubata,Kisaburo Nagamune,Nobutoshi Murakami,Patrick Merkel,Zakayi Kabututu,Samuel K. Martin,Taba M. Kalulu,Haq Mustakuk,Mitsuru Yoshida,Mayumi Ohnishi-Kameyama,Taroh Kinoshita,Michael Duszenko,Yoshihiro Urade, International Journal for Parasitology, Elsevier Ltd, Vol. 35, No. 1, p. 91-103, 2005/01
  • GPI-anchor deficiency in myeloid cells causes impaired FcγR effector functions, Wouter L.W. Hazenbos,Björn E. Clausen,Junji Takeda,Taroh Kinoshita, Blood, Vol. 104, No. 9, p. 2825-2831, 2004/11/01
  • Enhanced responses of glycosylphosphatidylinositol anchor-deficient T lymphocytes, Wouter L.W. Hazenbos,Yoshiko Murakami,Jun Ichi Nishimura,Junji Takeda,Taroh Kinoshita, Journal of Immunology, AMER ASSOC IMMUNOLOGISTS, Vol. 173, No. 6, p. 3810-3815, 2004/09/15
  • Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene, Kosuke Yusa,Kyoji Horie,Gen Kondoh,Michiyoshi Kouno,Yusuke Maeda,Taroh Kinoshita,Junji Takeda, Nature, Vol. 429, No. 6994, p. 896-899, 2004/06/24
  • Surface sialic acids taken from the host allow trypanosome survival in Tsetse fly vectors, Kisaburo Nagamune,Alvaro Acosta-Serrano,Haruki Uemura,Reto Brun,Christina Kunz-Renggli,Yusuke Maeda,Michael A.J. Ferguson,Taroh Kinoshita, Journal of Experimental Medicine, Vol. 199, No. 10, p. 1445-1450, 2004/05/17
  • Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan, Jun Ichi Nishimura,Yuzuru Kanakura,Russell E. Ware,Tsutomu Shichishima,Hideki Nakakuma,Haruhiko Ninomiya,Carlos M. Decastro,Sharon Hall,Akihisa Kanamaru,Keith M. Sullivan,Hideaki Mizoguchi,Mitsuhiro Omine,Taroh Kinoshita,Wendell F. Rosse, Medicine, Vol. 83, No. 3, p. 193-207, 2004/05
  • PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor, Yoshiko Murakami,Uamporn Siripanyapinyo,Yeongjin Hong,Ji Young Kang,Sonoko Ishihara,Hideki Nakakuma,Yusuke Maeda,Taroh Kinoshita, Molecular Biology of the Cell, AMER SOC CELL BIOLOGY, Vol. 14, No. 10, p. 4285-4295, 2003/10/01
  • GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits, Kisaburo Nagamune,Kazuhito Ohishi,Hisashi Ashida,Yeonchul Hong,Jun Hino,Kenji Kangawa,Norimitsu Inoue,Yusuke Maeda,Taroh Kinoshita, Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 19, p. 10682-10687, 2003/09/16
  • Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins, Yeongjin Hong,Kazuhito Ohishi,Ji Young Kang,Satoshi Tanaka,Norimitsu Inoue,Jun Ichi Nishimura,Yusuke Maeda,Taroh Kinoshita, Molecular Biology of the Cell, Vol. 14, No. 5, p. 1780-1789, 2003/05/01
  • Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge, Kazuhito Ohishi,Kisaburo Nagamune,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 278, No. 16, p. 13959-13967, 2003/04
  • Molecular genetics of paroxysmal nocturnal hemoglobinuria, Norimitsu Inoue,Yoshiko Murakami,Taroh Kinoshita, International Journal of Hematology, Carden Jennings Publishing Co. Ltd, Vol. 77, No. 2, p. 107-112, 2003/02
  • Two possible mechanisms for escape of GPI(-) cells from the immunological attack, Y Murakami,H Kosaka,J Takeda,T Kinoshita, PAROXYSMAL NOCTURNAL HEMOGLOBINURIA AND RELATED DISORDERS, SPRINGER-VERLAG TOKYO, p. 225-227, 2003
  • Inefficient response of t lymphocytes to glycosylphosphatidylinositol anchor-negative cells: Implications for paroxysmal nocturnal hemoglobinuria, Yoshiko Murakami,Hiroshi Kosaka,Yusuke Maeda,Jun Ichi Nishimura,Norimitsu Inoue,Kazuhito Ohishi,Masaru Okabe,Junji Takeda,Taroh Kinoshita, Blood, Vol. 100, No. 12, p. 4116-4122, 2002/12/01
  • Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction, Chieko Yokoyama,Tomoko Yabuki,Manabu Shimonishi,Masayuki Wada,Toshihisa Hatae,Susumu Ohkawara,Junji Takeda,Taroh Kinoshita,Masaru Okabe,Tadashi Tanabe, Circulation, Vol. 106, No. 18, p. 2397-2403, 2002/10/29
  • Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum α-toxin, Yeongjin Hong,Kazuhito Ohishi,Norimitsu Inoue,Ji Young Kang,Hiroaki Shime,Yasuhiko Horiguchi,F. Gisou Van der Goot,Nakaba Sugimoto,Taroh Kinoshita, EMBO Journal, Vol. 21, No. 19, p. 5047-5056, 2002/10/01
  • Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex, Saulius Vainauskas,Yusuke Maeda,Henry Kurniawan,Taroh Kinoshita,Anant K. Menon, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 34, p. 30535-30542, 2002/08/23
  • Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro, Shoichi Nagakura,Sonoko Ishihara,Daniel E. Dunn,Jun Ichi Nishimura,Tatsuya Kawaguchi,Kentaro Horikawa,Michihiro Hidaka,Tadashi Kagimoto,Nozomu Eto,Hiroaki Mitsuya,Taroh Kinoshita,Neal S. Young,Hideki Nakakuma, Blood, Vol. 100, No. 3, p. 1031-1037, 2002/08/01
  • Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria, Jun Ichi Nishimura,Toshiyuki Hirota,Yuzuru Kanakura,Takashi Machii,Takashi Kageyama,Shoichi Doi,Hiroshi Wada,Toru Masaoka,Yoshio Kanayama,Hiroshi Fujii,Nobumasa Inoue,Maki Kuwayama,Norimitsu Inoue,Kazuhito Ohishi,Taroh Kinoshita, Blood, Vol. 99, No. 8, p. 2748-2751, 2002/04
  • The glycan core of GPI-anchored proteins modulates aerolysin binding but is not sufficient: The polypeptide moiety is required for the toxin-receptor interaction, Laurence Abrami,Marie Claire Velluz,Yeongjin Hong,Kazuhito Ohishi,Angela Mehlert,Michael Ferguson,Taroh Kinoshita,F. Gisou van der Goot, FEBS Letters, ELSEVIER SCIENCE BV, Vol. 512, No. 1-3, p. 249-254, 2002/02/13
  • Relationship between aplastic anemia and paroxysmal nocturnal hemoglobinuria, Taroh Kinoshita,Norimitsu Inoue, International Journal of Hematology, CARDEN JENNINGS PUBL CO LTD, Vol. 75, No. 2, p. 117-122, 2002/02
  • The GPI1 homologue from Plasmodium falciparum complements a Saccharomyces cerevisiae GPI1 anchoring mutant, Hosam Shams-Eldin,Nahid Azzouz,Mamdouh H. Kedees,Peter Orlean,Taroh Kinoshita,Ralph T. Schwarz, Molecular and Biochemical Parasitology, Elsevier, Vol. 120, No. 1, p. 73-81, 2002
  • Transgenic pigs expressing human decay-accelerating factor regulated by porcine MCP gene promoter, Hiroshi Murakami,Hiroshi Nagashima,Yoichi Takahagi,Shuji Miyagawa,Tatsuya Fujimura,Koji Toyomura,Rie Nakai,Mako Yamada,Takashi Kurihara,Tamotsu Shigehisa,Masaru Okabe,Tsukasa Seya,Ryota Shirakura,Taroh Kinoshita, Molecular Reproduction and Development, Vol. 61, No. 3, p. 302-311, 2002
  • Cross-talk between Caveolae and Glycosylphosphatidylinositol-rich Domains, Laurence Abrami,Marc Fivaz,Toshihide Kobayashi,Taroh Kinoshita,Robert G. Parton,F. Gisou Van der Goot, Journal of Biological Chemistry, Vol. 276, No. 33, p. 30729-30736, 2001/08/17
  • PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8, K. Ohishi,N. Inoue,T. Kinoshita, EMBO Journal, Vol. 20, No. 15, p. 4088-4098, 2001/08/01
  • Efficient retrovirus-mediated PIG-A gene transfer and stable restoration of GPI-anchored protein expression in cells with the PNH phenotype, Jun Ichi Nishimura,Ken L. Phillips,Russell E. Ware,Sharon Hall,Lee Wilson,Tracy L. Gentry,Thad A. Howard,Yoshiko Murakami,Masaru Shibano,Takashi Machii,Eli Gilboa,Yuzuru Kanakura,Junji Takeda,Taroh Kinoshita,Wendell F. Rosse,Clay A. Smith, Blood, Vol. 97, No. 10, p. 3004-3010, 2001/05/15
  • Its8, a Fission Yeast Homolog of Mcd4 and Pig-n, Is Involved in GPI Anchor Synthesis and Shares an Essential Function with Calcineurin in Cytokinesis, Tomoko Yada,Reiko Sugiura,Ayako Kita,Yuumi Itoh,Yabin Lu,Yeongjin Hong,Taroh Kinoshita,Hisato Shuntoh,Takayoshi Kuno, Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology Inc., Vol. 276, No. 17, p. 13579-13586, 2001/04
  • PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER, Yusuke Maeda,Reika Watanabe,Claire L. Harris,Yeongjin Hong,Kazuhito Ohishi,Keiko Kinoshita,Taroh Kinoshita, EMBO Journal, OXFORD UNIV PRESS, Vol. 20, No. 1-2, p. 250-261, 2001/01/15
  • Porcine MCP gene promoter directs high level expression of human DAF (CD55) in transgenic mice, Hiroshi Murakami,Yoichi Takahagi,Masao Yoshitatsu,Shuji Miyagawa,Tatsuya Fujimura,Koji Toyomura,Tamotsu Shigehisa,Ryota Shirakura,Taroh Kinoshita, Immunobiology, Elsevier GmbH, Vol. 201, No. 5, p. 583-597, 2000/04
  • Altered T cell development in human thymorea is related to impairment of MHC class II transactivator expression induced by interferon-gamma (IFN-γ), Y. Kadota,Meinoshin Okumura,S. Miyoshi,S. Kitagawa-Sakakida,M. Inoue,H. Shiono,Y. Maeda,T. Kinoshita,R. Shirakura,H. Matsuda, Clinical and Experimental Immunology, Vol. 121, No. 1, p. 59-68, 2000
  • Molecular remodelling of human CD46 for xenotransplantation: Designing a potent complement regulator without measles virus receptor activity, N. A. Begum,Y. Murakami,S. Mikata,M. Matsumoto,M. Hatanaka,S. Nagasawa,T. Kinoshita,T. Seya, Immunology, Vol. 100, No. 1, p. 131-139, 2000
  • Production of transgenic pigs expressing human DAF (CD55) regulated by the porcine MCP gene promoter, H. Murakami,H. Nagashima,Y. Takahagi,T. Fujimura,S. Miyagawa,M. Okabe,T. Seya,T. Shigehisa,N. Taniguchi,R. Shirakura,T. Kinoshita, Transplantation Proceedings, Vol. 32, No. 7, p. 2505-2506, 2000
  • Dissecting and manipulating the pathway for glycosylphosphatidylinositol-anchor biosynthesis, Taroh Kinoshita,Norimitsu Inoue, Current Opinion in Chemical Biology, CURRENT BIOLOGY LTD, Vol. 4, No. 6, p. 632-638, 2000
  • A novel glycosylphosphatidyl inositol-anchored protein on human leukocytes: A possible role for regulation of neutrophil adherence and migration, Kichiya Suzuki,Tadashi Watanabe,Shin Ichi Sakurai,Kazuhisa Ohtake,Taroh Kinoshita,Akemi Araki,Teizo Fujita,Hiroshi Takei,Yuji Takeda,Yukiko Sato,Takao Yamashita,Yoshihiko Araki,Fujiro Sendo, Journal of Immunology, American Association of Immunologists, Vol. 162, No. 7, p. 4277-4284, 1999/04
  • CD59-deficient blood cells and PIG-A gene abnormalities in Japanese patients with aplastic anaemia, Yasuhiko Azenishi,Etsuko Ueda,Takashi Machii,Jun Ichi Nishimura,Toshiyuki Hirota,Masaru Shibano,Shinji Nakao,Taroh Kinoshita,Hideaki Mizoguchi,Teruo Kitani, British Journal of Haematology, Blackwell Publishing Ltd., Vol. 104, No. 3, p. 523-529, 1999
  • Genotypic, immunophenotypic and clinical features of Thai patients with paroxysmal nocturnal haemoglobinuria, Patcharin Pramoonjago,Kriangsakdi Pakdeesuwan,Uamporn Siripanyaphinyo,Sriprapa Chinprasertsuk,Taroh Kinoshita,Wanchai Wanachiwanawin, British Journal of Haematology, Blackwell Publishing Ltd., Vol. 105, No. 2, p. 497-504, 1999
  • Human and mouse GPAA1 (Glycosylphosphatidylinositol anchor attachment 1) genes: Genomic structures, chromosome loci and the presence of a minor class intron, N. Inoue,K. Ohishi,Y. Endo,T. Fujita,J. Takeda,Taroh Kinoshita, Cytogenetics and Cell Genetics, Vol. 84, No. 3-4, p. 199-205, 1999
  • Antibody binding to individual short consensus repeats of decay- accelerating factor enhances enterovirus cell attachment and infectivity, Darren R. Shafren,Douglas J. Dorahy,Rick F. Thorne,Taroh Kinoshita,Richard D. Barry,Gordon F. Burns, Journal of Immunology, Vol. 160, No. 5, p. 2318-2323, 1998/03/01
  • Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase), Masato Matsuki,Fumiyoshi Yamashita,Akemi Ishida-Yamamoto,Keiko Yamada,Chikako Kinoshita,Shinji Fushiki,Eiichiro Ueda,Yohichi Morishima,Kohichi Tabata,Hirokazu Yasuno,Mitsuru Hashida,Hajime Iizuka,Masahito Ikawa,Masaru Okabe,Gen Kondoh,Taroh Kinoshita,Junji Takeda,Kiyofumi Yamanishi, Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, No. 3, p. 1044-1049, 1998/02/03
  • Differentiation-dependent changes in human trophoblast expression of decay-accelerating factor are modulated by 3',5' cyclic adenosine monophosphate, I. K. Zarkadis,A. Omigbodun,A. Forson,P. Ziolkiewicz,T. Kinoshita,J. D. Lambris,C. Coutifaris, Journal of the Society for Gynecologic Investigation, Vol. 4, No. 1, p. 47-53, 1997/01
  • Expression cloning of pig-l, a gene involved in deacetylation of n-acetylglucosaminyl phosphatidylinositol, a gpi intermediate, N. Nakamura,N. Lnoue,R. Watanabe,M. Larahashl,J. Lakeda,V. L. Stevens,T. Kinoshita, FASEB Journal, Vol. 11, No. 9, 1997
  • GPI-N-acetylglucosaminyl transferase for the first step of glycosylphosphatidylinositol biosynthesis is mediated by protein complex composed of PIG-A, PIG-H, PIG-C and HGPI 1, R. Watanabe,N. Inoue,B. Westfall,C. H. Taron,P. Orlean,J. Takeda,T. Kinoshita, FASEB Journal, Vol. 11, No. 9, 1997
  • Mouse GAA1 homologue is involved in transfeit of the GPI anchor to proteins, K. Ohishi,N. Inoue,J. Takeda,M. E. Medof,D. Hamburger,H. Riezman,T. Kinoshita, FASEB Journal, Vol. 11, No. 9, 1997
  • A new rat gene involved in biosynthesis of dolichol-phosphate-mannose, Y. Maeda,S. Tomita,J. Takeda,T. Kinoshita, FASEB Journal, Vol. 11, No. 9, 1997
  • Biological consequences of defects in gpi-anchor processing, T. Kinoshita,J. Takeda, FASEB Journal, Vol. 11, No. 9, 1997
  • Genotypic and phenotypic implications in paroxysmal nocturnal hemoglobinuria (PNH): A preliminary investigation, Kriangsak Pakdeesuwan,Uamporn Siripanyaphinyo,Patcharin Pramoonjago,Kovit Pattanapanyasat,Prapon Wilairat,Taroh Kinoshita,Wanchai Wanachiwanawin, Southeast Asian Journal of Tropical Medicine and Public Health, Vol. 28, p. 58-63, 1997
  • Exposure of astrocytes to hypoxia/reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6, Osamu Hori,Masayasu Matsumoto,Keisuke Kuwabara,Yusuke Maeda,Hirokazu Ueda,Toshiho Ohtsuki,Taroh Kinoshita,Satoshi Ogawa,David M. Stern,Takenobu Kamada, Journal of Neurochemistry, Vol. 66, No. 3, p. 973-979, 1996/03
  • Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain, Keisuke Kuwabara,Masayasu Matsumoto,Jun Ikeda,Osamu Hori,Satoshi Ogawa,Yusuke Maeda,Kazuo Kitagawa,Naohiko Imuta,Taroh Kinoshita,David M. Stern,Hideki Yanagi,Takenobu Kamada, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 271, No. 9, p. 5025-5032, 1996/03/01
  • Protection of host from its own complement by membrane-bound complement inhibitors: C3 convertase inhibitors vs membrane attack complex inhibitors, T. Kinoshita, Research in Immunology, Vol. 147, No. 2, p. 100-103, 1996
  • Characterization of a complement receptor 2 (CR2, CD21) ligand binding site for C3: An initial model of ligand interaction with two linked short consensus repeat modules, H. Molina,S. J. Perkins,J. Guthridge,J. Gorka,T. Kinoshita,V. M. Holers, Journal of Immunology, Vol. 154, No. 10, p. 5426-5435, 1995
  • PIG-A gene abnormalities in Thai patients with paroxysmal nocturnal hemoglobinuria., P. Pramoonjago,W. Wanachiwanawin,S. Chinprasertsuk,K. Pattanapanyasat,J. Takeda,T. Kinoshita, The Southeast Asian journal of tropical medicine and public health, Vol. 26 Suppl 1, p. 322-324, 1995
  • Antibodies to murine complement receptor 1 and 2 can inhibit the antibody response in vivo without inhibiting T helper cell induction, S. Gustavsson,T. Kinoshita,B. Heyman, Journal of Immunology, Vol. 154, No. 12, p. 6524-6528, 1995
  • Mouse complement regulatory protein crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein, Youn Uck Kim,Taroh Kinoshita,Hector Molina,Dennis Hourcade,Tsukasa Seya,Lynne M. Wagner,V. Michael Holers, Journal of Experimental Medicine, Vol. 181, No. 1, p. 151-159, 1995/01/01
  • Expression Cloning Strategies for Glycosylphosphatidylinositol-Anchor Biosynthesis Enzymes and Regulators, Taroh Kinoshita,Toshio Miyata,Norimitsu Inoue,Junji Takeda, Methods in Enzymology, Vol. 250, No. C, p. 547-560, 1995
  • Hypoxia/reoxygenation-mediated induction of astrocyte interleukin 6: A paracrine mechanism potentially enhancing neuron survival, Yusuke Maeda,Masayasu Matsumoto,Osamu Hori,Keisuke Kuwabara,Satoshi Ogawa,Shi Du Yan,Toshiho Ohtsuki,Taroh Kinoshita,Takenobu Kamada, Journal of Experimental Medicine, Vol. 180, No. 6, p. 2297-2308, 1994/12/01
  • Analysis of C3b/C3d binding sites and factor I cofactor regions within mouse complement receptors 1 and 2, Hector Molina,Taroh Kinoshita,Carol Brenner Webster,V. Michael Holers, Journal of Immunology, Vol. 153, No. 2, p. 789-795, 1994/07/15
  • Metabolic and Biosynthetic Alterations in Cultured Astrocytes Exposed to Hypoxia/Reoxygenation, Osamu Hori,Masayasu Matsumoto,Yusuke Maeda,Hirokazu Ueda,Toshiho Ohtsuki,David M. Stern,Taroh Kinoshita,Satoshi Ogawa,Takenobu Kamada, Journal of Neurochemistry, Vol. 62, No. 4, p. 1489-1495, 1994/04
  • Expression cloning of genes for GPI-anchor biosynthesis., T. Kinoshita,M. Takahashi,N. Inoue,T. Miyata,J. Takeda, Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], Vol. 27, No. 2, p. 127-132, 1994/02
  • A beneficial role of bile pigments as an endogenous tissue protector: Anti-complement effects of biliverdin and conjugated bilirubin, Tatsuyoshi Nakagami,Koji Toyomura,Taroh Kinoshita,Seiji Morisawa, BBA - General Subjects, Vol. 1158, No. 2, p. 189-193, 1993/10/03
  • β<inf>2</inf>-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis, Toshio Miyata,Osamu Oda,Reiko Inagi,Yoshiyasu Iida,Norie Araki,Norio Yamada,Seikoh Horiuchi,Naoyuki Taniguchi,Kenji Maeda,Taroh Kinoshita, Journal of Clinical Investigation, The American Society for Clinical Investigation, Vol. 92, No. 3, p. 1243-1252, 1993/09
  • A monoclonal antibody against human decay-accelerating factor (DAF, CD55), D17, which lacks reactivity with semen-DAF, Tomoko Hara,Misako Matsumoto,Yasuo Fukumori,Shuji Miyagawa,Michiyo Hatanaka,Taroh Kinoshita,Tsukasa Seya,Hitoshi Akedo, Immunology Letters, Vol. 37, No. 2-3, p. 145-152, 1993/08
  • Antibody Feedback Regulation in MRL/lpr Mice, Birgitta Heyman,Susanne Gustavsson,Chikashi Kusakari,Masato Nose,Taroh Kinoshita,Lars Klareskog,Andrej Tarkowski, Journal of Autoimmunity, Vol. 6, No. 4, p. 437-448, 1993/08
  • The biological roles of the third component of complement in osteoclast formation, Toshiyuki Sato,Etsuko Abe,Cheng He Jin,Mei Hua Hong,Takenobu Katagiri,Taroh Kinoshita,Norio Amizuka,Hidehiro Ozawa,Tatsuo Suda, Endocrinology, Vol. 133, No. 1, p. 397-404, 1993/07
  • Functional properties of the allotypes of mouse complement regulatory protein, factor H: Difference of compatibility of each allotype with human factor I, Okada Michiyo,Kojima Ayako,Takano Hiromi,Harada Yoshinobu,Nonaka Mayumi,Nonaka Masaru,Kinoshita Taroh,Seya Tsukasa,Natsuume Sakai Shunnosuke, Molecular Immunology, Vol. 30, No. 9, p. 841-848, 1993/06
  • Characteristics of the epitope of protein-reactive anti-peptide antibodies, Akemi Ota,Jiro Seki,Xiao Liang Lin,Yu Zhao,Xiaohui Wang,Kiyoshi Kondo,Nobuo Sakato,Taroh Kinoshita,Hajime Fujio, Journal of Biochemistry, Oxford University Press, Vol. 113, No. 3, p. 314-320, 1993/03
  • The immunosuppressive action of anti-CD18 monoclonal antibody in rat heterotopic heart allotransplantation, Hiroshi Kameoka,Michio Ishibashi,Takuya Tamatani,Yuji Takano,Abdelhakim Moutabarrik,Hongsi Jiang,Yukito Kokado,Shiro Takahara,Akihiko Okuyama,Taroh Kinoshita,Masayuki Miyasaka, Transplantation, Vol. 55, No. 3, p. 665-667, 1993/03
  • Comparative immunosuppressive effect of anti-CD18 and anti-CD11a monoclonal antibodies on rat heart allotransplantation, H. Kameoka,M. Ishibashi,T. Tamatani,Y. Takano,A. Moutabarrik,H. Jiang,Y. Kokado,S. Takahara,M. Miyasaka,A. Okuyama,T. Kinoshita,T. Sonoda, Transplantation Proceedings, Vol. 25, No. 1, p. 833-836, 1993
  • Inhibitory effect of the complement receptor-specific monoclonal antibody on the induced antibody response and the role of CD4<sup>+</sup> and CD8<sup>+</sup> T-cells in the rat to mouse xenotransplantation, G. Matsumiya,R. Shirakura,S. Miyagawa,S. Nakata,S. Nakano,T. Kinoshita,H. Matsuda, Transplantation Proceedings, Vol. 25, No. 1, p. 402-404, 1993
  • Ligand specificities of mouse complement receptor types 1 (CR1) and 2 (CR2) purified from spleen cells, Patcharin Pramoonjago,Junjl Takeda,Youn Uck Kim,Kozo Inoue,Taroh Kinoshita, International Immunology, Vol. 5, No. 4, p. 337-343, 1993
  • Cloning of a human gene, PIG-F, a component of glycosyl- phosphatidylinositol anchor biosynthesis, by a novel expression cloning strategy, N. Inoue,T. Kinoshita,T. Orii,J. Takeda, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 268, No. 10, p. 6882-6885, 1993
  • Deficient surface expression of glycosylphosphatidylinositol-anchored proteins in B cell lines established from patients with paroxysmal nocturnal hemoglobinuria, Etsuko Ueda,Jun ichl Nishimura,Teruo Kitani,Kaori Nasu,Takashi Kageyama,Youn Uck Kim,Junjl Takeda,Taroh Kinoshita, International Immunology, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 4, No. 11, p. 1263-1271, 1992/11
  • Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor, K. E. Coyne,S. E. Hall,E. S. Thompson,M. A. Arce,T. Kinoshita,T. Fujita,D. J. Anstee,W. Rosse,D. M. Lublin, Journal of Immunology, Vol. 149, No. 9, p. 2906-2913, 1992
  • Bactericidal activity of C9-deficient human serum, P. Pramoonjago,T. Kinoshita,K. Hong,Y. Takata-Kozono,H. Kozono,R. Inagi,K. Inoue, Journal of Immunology, Vol. 148, No. 3, p. 837-843, 1992
  • Phylogeny of the third component of complement, C3: Analysis of the conservation of human CR1, CR2, H, and B binding sites, concanavalin A binding sites, and thiolester bond in the C3 from different species, Jochem Alsenz,David Avila,Hartwig P. Huemer,Inmaculada Esparza,J. David Becherer,Taroh Kinoshita,Yang Wang,Sabine Oppermann,John D. Lambris, Developmental and Comparative Immunology, Vol. 16, No. 1, p. 63-76, 1992
  • Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and crry, the two genetic homologues of human CR1, Hector Molina,Winnie Wong,Taroh Kinoshita,Carol Brenner,Sharon Foley,V. Michael Holers, Journal of Experimental Medicine, Vol. 175, No. 1, p. 121-123, 1992/01/01
  • Fluid-phase activation of the alternative pathway of complement by excess factor D in regularly dialyzed patients, T. Miyata,R. Inagi,K. Hong,Y. Iida,O. Oda,T. Kinoshita,K. Inoue,A. Miyama,K. Maeda, Nephron, Vol. 60, No. 2, p. 144-149, 1992
  • Role of TraT protein, an anticomplementary protein produced in Escherichia coli by R100 factor, in serum resistance, P. Pramoonjago,M. Kaneko,T. Kinoshita,E. Ohtsubo,J. Takeda,K. Hong,R. Inagi,K. Inoue, Journal of Immunology, Vol. 148, No. 3, p. 827-836, 1992
  • Inhibition of immunological memory and T‐independent humoral responses by monoclonal antibodies specific for murine complement receptors, Erik J. Wiersma,Taroh Kinoshita,Birgitta Heyman, European Journal of Immunology, Vol. 21, No. 10, p. 2501-2506, 1991/10
  • Preferential inactivation of the C5 convertase of the alternative complement pathway by factor I and membrane cofactor protein (MCP), Seya Tsukasa,Okada Michiyo,Matsumoto Misako,Hong Kyongsu,Kinoshita Taroh,John P. Atkinson, Molecular Immunology, Vol. 28, No. 10, p. 1137-1147, 1991/10
  • Paroxysmal nocturnal hemoglobinuria and GPI-anchored membrane proteins, T. Kinoshita, Rinsho byori. The Japanese journal of clinical pathology, Vol. Suppl 91, p. 74-81, 1991/09
  • Deficiency of complement decay-accelerating factor (DAF, CD55) in non-Hodgkin's lymphoma, Hiroko Fukuda,Tsukasa Seya,Tomoko Hara,Misako Matsumoto,Taroh Kinoshita,Toru Masaoka, Immunology Letters, Vol. 29, No. 3, p. 205-209, 1991/08
  • Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo, G. Thyphronitis,T. Kinoshita,K. Inoue,J. E. Schweinle,G. C. Tsokos,E. S. Metcalf,F. D. Finkelman,J. E. Balow, Journal of Immunology, Vol. 147, No. 1, p. 224-230, 1991
  • Analysis of Epstein-Barr virus-binding sites on complement receptor 2 (CR2/CD21) using human-mouse chimeras and peptides: At least two distinct sites are necessary for ligand-receptor interaction, H. Molina,C. Brenner,S. Jacobi,J. Gorka,J. C. Carel,T. Kinoshita,V. M. Holers, Journal of Biological Chemistry, Vol. 266, No. 19, p. 12173-12179, 1991
  • Reconstitution of C5 convertase of the alternative complement pathway with isolated C3b dimer and factors B and D, K. Hong,T. Kinoshita,P. Pramoonjago,Youn Uck Kim,T. Seya,K. Inoue, Journal of Immunology, Vol. 146, No. 6, p. 1868-1873, 1991
  • Murine monoclonal anti-Ba antibody that enhances haemolytic activity of factor B, E. Tanaka,K. Hong,T. Kinoshita,Y. Takata,H. Kozono,J. Takeda,A. Yoden,K. Inoue, Immunology, Vol. 73, No. 4, p. 383-387, 1991
  • Inherited complete deficiency of 20-kilodalton homologous restriction factor (cd59) as a cause of paroxysmal nocturnal hemoglobinuria, Manabu Yamashina,Etsuko Ueda,Taroh Kinoshita,Tsuyoshi Takami,Akitsugu Ojima,Hiromasa Ono,Hiroshi Tanaka,Naomi Kondo,Tadao Orii,Noriko Okada,Hidechika Okada,Kozo Inoue,Teruo Kitani, New England Journal of Medicine, Vol. 323, No. 17, p. 1184-1189, 1990/10/25
  • Inhibition of the alternative C3 convertase and classical C5 convertase of complement by group A streptococcal M protein, K. Hong,T. Kinoshita,J. Takeda,H. Kozono,P. Pramoonjago,Y. U. Kim,K. Inoue, Infection and Immunity, Vol. 58, No. 8, p. 2535-2541, 1990
  • Proteolytic elimination of decay-accelerating factor (DAF): Lytic abnormality coincides with removal of DAF in papain-treated human erythrocytes, Seya Tsukasa,Inoue Hiroaki,Okada Michiyo,Matsumoto Misako,Kitamura Hajime,Kinoshita Taroh,Akedo Hitoshi, Molecular Immunology, Vol. 27, No. 1, p. 69-78, 1990/01
  • Interactions between murine B lymphocyte surface membrane molecules. Loaded but not free receptors for complement and the Fc portion of IgG Co-Cap independently with cross-linked surface Ig, G. C. Tsokos,T. Kinoshita,G. Thyphronitis,A. D. Patel,H. B. Dickler,F. D. Finkelman, Journal of Immunology, Vol. 144, No. 1, p. 239-243, 1990
  • Acetylcholinesterase and lymphocyte function-associated antigen 3 found on decay-accelerating factor-negative erythrocytes from some patients with paroxysmal nocturnal hemoglobinuria are lost during erythrocyte aging, E. Ueda,T. Kinoshita,T. Terasawa,T. Shichishima,Y. Yawata,K. Inoue,T. Kitani, Blood, Vol. 75, No. 3, p. 762-769, 1990
  • A molecular and immunochemical characterization of mouse CR2: Evidence for a single gene model of mouse complement receptors 1 and 2, H. Molina,T. Kinoshita,K. Inoue,J. C. Carel,V. M. Holers, Journal of Immunology, Vol. 145, No. 9, p. 2974-2983, 1990
  • Complement receptors, T. Kinoshita, Seikagaku. The Journal of Japanese Biochemical Society, Vol. 61, No. 8, p. 704-709, 1989/08
  • Different membrane anchors of FCγRIII (CD16) on K/NK-lymphocytes and neutrophils. Protein- vs lipid-anchor, E. Ueda,T. Kinoshita,J. Nojima,K. Inoue,T. Kitani, Journal of Immunology, Vol. 143, No. 4, p. 1274-1277, 1989
  • The low C5 convertase activity of the C4A6 allotype of human complement component C4, T. Kinoshita,A. W. Dodds,S. K.A. Law,K. Inoue, Biochemical Journal, Vol. 261, No. 3, p. 743-748, 1989
  • Different distribution of decay-accelerating factor on hematopoietic progenitors from normal individuals and patients with paroxysmal nocturnal hemoglobinuria, A. Kanamaru,K. Okuda,E. Ueda,T. Kitani,T. Kinoshita,K. Nagai, Blood, Vol. 72, No. 2, p. 507-511, 1988
  • Rapid and simple measurement of human C5a-des-Arg level in plasma or serum using monoclonal antibodies, Junji Takeda,Taroh Kinoshita,Yuko Takata,Haruo Kozono,Etsuko Tanaka,Kyongsu Hong,Kozo Inoue, Journal of Immunological Methods, Vol. 101, No. 2, p. 265-270, 1987/08/03
  • Relationship between decay accelerating factor deficiency, diminished acetylcholinesterase activity, and defective terminal complement pathway restriction in paroxymal nocturnal hemoglobinuria erythrocytes, M. E. Medof,A. Gottlieb,T. Kinoshita,S. Hall,R. Silber,V. Nussenzweig,W. F. Rosse, Journal of Clinical Investigation, Vol. 80, No. 1, p. 165-174, 1987
  • A high m.w. form of decay-accelerating factor (DAF-2) exhibits size abnormalities in paroxysmal nocturnal hemoglobinuria erythrocytes, T. Kinoshita,S. I. Rosenfeld,V. Nussenzweig, Journal of Immunology, Vol. 138, No. 9, p. 2994-2998, 1987
  • Membrane-bound C4b interacts endogenously with complement receptor CRI of human red cells, Taroh Kinoshita,M. Edward Medof,Kyongsu Hong,Victor Nussenzweig, Journal of Experimental Medicine, Vol. 164, No. 5, p. 1377-1388, 1986/11/01
  • Decay-accelerating factor is present on cultured human umbilical vein endothelial cells, Adam S. Asch,Taroh Kinoshita,Eric A. Jaffe,Victor Nussenzweig, Journal of Experimental Medicine, Vol. 163, No. 1, p. 221-226, 1986/01/01
  • Endogenous association of decay-accelerating factor (DAF) with C4b and C3b on cell membranes, T. Kinoshita,M. E. Medof,V. Nussenzweig, Journal of Immunology, Vol. 136, No. 9, p. 3390-3395, 1986
  • Number of Hits Necessary for Complement-Mediated Hemolysis, Junji Takeda,Haruo Kozono,Yuko Takata,Taroh Kinoshita,Etsuko Tanaka,Kozo Inoue, MICROBIOLOGY and IMMUNOLOGY, Vol. 30, No. 5, p. 461-468, 1986
  • Amelioration of lytic abnormalities of paroxysmal nocturnal hemoglobinuria with decay-accelerating factor, M. E. Medof,T. Kinoshita,R. Silber,V. Nussenzweig, Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, No. 9, p. 2980-2984, 1985
  • Partial correction of the lytic abnormalities of paroxysmal nocturnal hemoglobinuria cells with decay accelerating factor, M. E. Medof,T. Kinoshita,R. Silber,V. Nussenzweig, Federation Proceedings, Vol. 44, No. 3, 1985
  • Regulatory proteins for the activated third and fourth components of complement (C3b and C4b) in mice. II. Identification and properties of complement receptor type 1(CR1), T. Kinoshita,S. Lavoie,V. Nussenzweig, Journal of Immunology, Vol. 134, No. 4, p. 2564-2570, 1985
  • Regulatory proteins for the activated third and fourth components of complement (C3b and C4b) in mice. I. Isolation and characterization of factor H: the serum cofactor for the C3b/C4b inactivator (Factor I), Taroh Kinoshita,Victor Nussenzweig, Journal of Immunological Methods, Vol. 71, No. 2, p. 247-257, 1984/07/06
  • Functional properties of factor H and the membrane complement receptor for C3b, C4b (CR1) in mice, T. Kinoshita,V. Nussenzweig, Federation Proceedings, Vol. 43, No. 6, 1984
  • Effects of K-76 monocarboxylic acid, an anticomplementary agent, on various in vivo immunological reactions and on experimental glomerulonephritis, W. Miyazaki,T. Izawa,Y. Nakano,M. Shinohara,K. Hing,T. Kinoshita,K. Inoue, Complement, Vol. 1, No. 3, p. 134-146, 1984
  • Inhibition of immune precipitation by complement, K. Hong,Y. Takata,K. Sayama,H. Kozono,J. Takeda,Y. Nakano,T. Kinoshita,K. Inoue, Journal of Immunology, Vol. 133, No. 3, p. 1464-1470, 1984
  • Interaction of the Eighth Component of Guinea Pig Complement (C8) with the Membrane‐Bound C5b‐7 Complex: The Binding Site of C8 to C5b‐7 Is Formed on Association of the α‐γ Subunit with the β‐Chain, Taroh Kinoshita,Kyongsu Hong,Kozo Inoue, Microbiology and Immunology, Vol. 27, No. 4, p. 369-375, 1983/04
  • Eighth component of guinea pig complement: Purification and characterization, Kinoshita Taroh,Hong Kyongsu,Kondo Kiyoshi,Inoue Kozo, Molecular Immunology, Vol. 19, No. 4, p. 589-597, 1982/04
  • Effect of trysinization on the activity of human factor H, K. Hong,T. Kinoshita,Y. Dohi,K. Inoue, Journal of Immunology, Vol. 129, No. 2, p. 647-652, 1982
  • Soluble C5b-9 complex of guinea pig complement: Demonstration of its heterogeneity and the mechanism of its C9 hemolytic activity as transfer of reversibly bound C9 molecules from the complex, Kinoshita Taroh,Hong Kyongsu,Inoue Kozo, Molecular Immunology, Vol. 18, No. 5, p. 423-431, 1981/05
  • Inhibitory effect of K-76 monocarboxylic acid, an anticomplementary agent, on the C3b inactivator system, K. Hong,T. Kinoshita,H. Kitajima,K. Inoue, Journal of Immunology, Vol. 127, No. 1, p. 104-108, 1981
  • Simple methods for preparing EAC1,4b,2a,3b and EAC4b,3b with human or guinea pig complement components using an anticomplementary agent, K-76 monocarboxylic acid, K. Hong,T. Kinoshita,K. Inoue, Journal of Immunology, Vol. 127, No. 1, p. 109-114, 1981
  • Fifth component of guinea pig complement: Purification and characterization, T. Kinoshita,K. Hong,K. Kondo,K. Inoue, Journal of Immunology, Vol. 126, No. 6, p. 2414-2418, 1981
  • A Complement Inhibitor Produced by Stachybotrys complementi, nov. sp. K-76, a New Species of Fungi Imperfecti, Wasei Miyazaki,Hisashi Tamaoka,Masanao Shinohara,Hirotsugu Kaise,Taketoshi Izawa,Yoshimasa Nakano,Taroh Kinoshita,Kyongsu Hong,Kozo Inoue, MICROBIOLOGY and IMMUNOLOGY, Vol. 24, No. 11, p. 1091-1108, 1980
  • C9 hemolytic activity of the soluble C5b-9 complex of guinea pig complement, analogous to human SC5b-9, T. Kinoshita,K. Hong,K. Inoue, Journal of Immunology, Vol. 123, No. 5, p. 1989-1995, 1979
  • An anticomplementary agent, K-76 monocarboxylic acid: Its site and mechanism of inhibition of the complement activation cascade, K. Hong,T. Kinoshita,W. Miyazaki,T. Izawa,K. Inoue, Journal of Immunology, Vol. 122, No. 6, p. 2418-2423, 1979
  • Bactericidal activity of the normal, cell free hemolymph of silkworms (Bombyx mori), T. Kinoshita,K. Inoue, Infection and Immunity, Vol. 16, No. 1, p. 32-36, 1977
  • Release of phospholipids from complement mediated lesions on the surface structure of Escherichia coli, K. Inoue,T. Kinoshita,M. Okada,Y. Akiyama, Journal of Immunology, Vol. 119, No. 1, p. 65-72, 1977
  • Release of phospholipids from liposomal model membrane damaged by antibody and complement, T. Kinoshita,K. Inoue,M. Okada,Y. Akiyama, Journal of Immunology, Vol. 119, No. 1, p. 73-78, 1977
  • Evidence for a one hit theory in the immune bactericidal reaction and demonstration of a multi hit response for hemolysis by streptolysin O and Clostridium perfringens theta toxin, Kozo Inoue,Yoko Akiyama,Taroh Kinoshita,Yasushi Higashi,Tsunehisa Amano, Infection and Immunity, Vol. 13, No. 2, p. 337-344, 1976

Misc.

  • Biosynthesis and biology of mammalian GPI-anchored proteins, Taroh Kinoshita, Open Biology, Vol. 10, No. 3, 2020/03/01
  • ‘Stealth’ corporate innovation: an emerging threat for therapeutic drug development, Dimitrios C. Mastellos,Anna M. Blom,E. Sander Connolly,Mohamed R. Daha,Brian V. Geisbrecht,Berhane Ghebrehiwet,Piet Gros,George Hajishengallis,V. Michael Holers,Markus Huber-Lang,Taroh Kinoshita,Tom E. Mollnes,Robert A. Montgomery,B. Paul Morgan,Bo Nilsson,Ruben Pio,Daniel Ricklin,Antonio M. Risitano,Ronald P. Taylor,Alberto Mantovani,John P.A. Ioannidis,John D. Lambris, Nature Immunology, Vol. 20, No. 11, p. 1409-1413, 2019/11/01
  • 上衣下出血後のWest症候群としてフォローしていたGPI欠損症の1例, 西村 洋子,村上 良子,木下 タロウ,谷河 純平,青天目 信,前垣 義弘, てんかん研究, (一社)日本てんかん学会, Vol. 36, No. 1, p. 68-68, 2018/06
  • 先天性GPI欠損症と鑑別を要した症例を含むZTTK症候群の新規3例の検討, 谷河 純平,岡本 伸彦,富永 康仁,北井 征宏,青天目 信,宮武 聡子,三宅 紀子,松本 直通,木下 タロウ,村上 良子,大薗 恵一, 脳と発達, (一社)日本小児神経学会, Vol. 50, No. Suppl., p. S380-S380, 2018/05
  • 補体関連疾患に対する網羅的な補体検査システムの構築, 井上 徳光,日高 義彦,大谷 克城,大塚 泰史,澤井 俊宏,宮田 敏行,大澤 勲,岡田 秀親,木下 タロウ,関根 英治,塚本 浩,中尾 実樹,水野 正司,村上 良子,堀内 孝彦,若宮 伸隆,TMAレジストリーチーム, 補体, (一社)日本補体学会, Vol. 54, No. 1, p. 19-21, 2017/09
  • Paroxysmal nocturnal haemoglobinuria, Anita Hill,Amy E. Dezern,Taroh Kinoshita,Robert A. Brodsky, Nature Reviews Disease Primers, Nature Publishing Group, Vol. 3, 2017/05/18
  • Molecular genetics, biochemistry, and biology of PNH, Vol. 58, No. 4, p. 353-362, 2017/04
  • Crystallographic analysis of murine p24γ2 Golgi dynamics domain, Masamichi Nagae,Dorothee Liebschner,Yusuke Yamada,Kana Morita-Matsumoto,Naohiro Matsugaki,Toshiya Senda,Morihisa Fujita,Taroh Kinoshita,Yoshiki Yamaguchi, Proteins: Structure, Function and Bioinformatics, Vol. 85, No. 4, p. 764-770, 2017/04
  • GPI-anchor-defective erythrocytes caused by somatically acquired mutation in paroxysmal nocturnal hemoglobinuria, Taroh Kinoshita, Seikagaku, Japanese Biochemical Society, Vol. 89, No. 3, p. 351-358, 2017
  • 血清GPIアンカー蛋白定量による先天性GPI欠損症スクリーニング, 高橋 幸利,西村 成子,高尾 恵美子,笠井 理沙,榎田 かおる,井上 有史,村上 良子,木下 タロウ,井上 徳光,九鬼 一郎,鈴木 保宏,谷河 純平,田中 総一郎,高山 留美子, 脳と発達, (一社)日本小児神経学会, Vol. 48, No. Suppl., p. S277-S277, 2016/05
  • Glycosylphosphatidylinositol (GPI) anchors: Biochemistry and cell biology: Introduction to a thematic review series, Taroh Kinoshita, Journal of Lipid Research, American Society for Biochemistry and Molecular Biology Inc., Vol. 57, No. 1, p. 4-5, 2016/01/01
  • Biosynthesis of GPI-anchored proteins: Special emphasis on GPI lipid remodeling, Taroh Kinoshita,Morihisa Fujita, Journal of Lipid Research, American Society for Biochemistry and Molecular Biology Inc., Vol. 57, No. 1, p. 6-24, 2016/01/01
  • Japan-Thailand collaboration research on infectious diseases: Promotion and hurdles, Shigeyuki Hamada,Naokazu Takeda,Taroh Kinoshita, Journal of Disaster Research, Vol. 9, No. 5, p. 784-792, 2014/10/01
  • Enzymatic mechanism of GPI anchor attachment clarified, Taroh Kinoshita, Cell Cycle, Taylor and Francis Inc., Vol. 13, No. 12, p. 1838-1839, 2014/06/15
  • Biochemistry of glycosylphosphatidylinositol (GPI) anchored proteins, Taroh Kinoshita, Seikagaku, Japanese Biochemical Society, Vol. 86, No. 5, p. 626-636, 2014
  • Biosynthesis and deficiencies of glycosylphosphatidylinositol, Taroh Kinoshita, Proceedings of the Japan Academy Series B: Physical and Biological Sciences, Japan Academy, Vol. 90, No. 4, p. 130-143, 2014
  • Transport of glycosylphosphatidylinositol-anchored proteins from the endoplasmic reticulum, Taroh Kinoshita,Yusuke Maeda,Morihisa Fujita, Biochimica et Biophysica Acta - Molecular Cell Research, ELSEVIER SCIENCE BV, Vol. 1833, No. 11, p. 2473-2478, 2013/11
  • GPI-anchor remodeling: Potential functions of GPI-anchors in intracellular trafficking and membrane dynamics, Morihisa Fujita,Taroh Kinoshita, Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1821, No. 8, p. 1050-1058, 2012/08
  • Persistently high quality of life conferred by coexisting congenital deficiency of terminal complement C9 in a paroxysmal nocturnal hemoglobinuria patient, Nobuyoshi Hanaoka,Yoshiko Murakami,Masahide Nagata,Shoichi Nagakura,Yuji Yonemura,Takashi Sonoki,Taroh Kinoshita,Hideki Nakakuma, Blood, Vol. 119, No. 16, p. 3866-3868, 2012/04
  • Guideline for hereditary angioedema (HAE) 2010 by the Japanese Association for Complement Research - Secondary publication, Takahiko Horiuchi,Hiroyuki Ohi,Isao Ohsawa,Teizo Fujita,Misao Matsushita,Noriko Okada,Tsukasa Seya,Tetsuro Yamamoto,Yuichi Endo,Michiyo Hatanaka,Nobutaka Wakamiya,Masashi Mizuno,Miki Nakao,Hidechika Okada,Hiroshi Tsukamoto,Misako Matsumoto,Norimitsu Inoue,Masaru Nonaka,Taroh Kinoshita, Allergology International, Japanese Society of Allergology, Vol. 61, No. 4, p. 559-562, 2012
  • Structural remodeling, trafficking and functions of glycosylphosphatidylinositol-anchored proteins, Yusuke Maeda,Taroh Kinoshita, Progress in Lipid Research, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 50, No. 4, p. 411-424, 2011/10
  • Inositol lipid metabolism in mycobacteria: Biosynthesis and regulatory mechanisms, Yasu S. Morita,Takeshi Fukuda,Chubert B.C. Sena,Yoshiki Yamaryo-Botte,Malcolm J. McConville,Taroh Kinoshita, Biochimica et Biophysica Acta - General Subjects, Vol. 1810, No. 6, p. 630-641, 2011/06
  • Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins, Morihisa Fujita,Taroh Kinoshita, FEBS Letters, Vol. 584, No. 9, p. 1670-1677, 2010/05
  • Preface, Fuyuhiko Tamanoi,Anant K. Menon,Taroh Kinoshita,Peter Orlean, Enzymes, Vol. 26, No. C, 2009
  • Chapter 1 Overview of GPI Biosynthesis, Taroh Kinoshita,Morihisa Fujita, Enzymes, Vol. 26, No. C, p. 1-30, 2009
  • Trypanosome glycosylphosphatidylinositol biosynthesis, Yeonchul Hong,Taroh Kinoshita, Korean Journal of Parasitology, Vol. 47, No. 3, p. 197-204, 2009
  • 糖鎖による生体膜近傍の細胞機能制御機構 Golgi装置の酸性化は新規アニオンチャンネルGPHRにより制御されグリコシル化において重要である(Acidification of the Golgi apparatus is regulated by GPHR, a novel anion channel, and critical for glycosylation), 前田 裕輔,井出 徹,小池 正人,内山 安男,木下 タロウ, 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, (公社)日本生化学会, Vol. 81回・31回, p. 2S12-4, 2008/11
  • Expression of HMGA2 in Blood Cells from Patients with Paroxysmal Nocturnal Hemoglobinuria, Yoshiko Murakami,Rieko Ohta,Norimitsu Inoue,Hideyoshi Noji,Tsutomu Shichishima,Jun-Ichi Nishimura,Yuzuru Kanakura,Taroh Kinoshita, BLOOD, AMER SOC HEMATOLOGY, Vol. 112, No. 11, p. 1179-1180, 2008/11
  • Designing sleeping sickness control, Taroh Kinoshita, ACS Chemical Biology, Vol. 3, No. 10, p. 601-603, 2008/10/17
  • Expression of HMGA2 in blood cells from patients with paroxysmal nocturnal haemoglobinuria, Yoshiko Murakami,Rieko Ohta,Norimitsu Inoue,Junichi Nishimura,Yuzuru Kanakura,Taroh Kinoshita, MOLECULAR IMMUNOLOGY, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 45, No. 16, p. 4177-4177, 2008/10
  • [Remodeling of GPI-anchored proteins]., Morihisa Fujita,Yusuke Maeda,Taroh Kinoshita, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 53, No. 12 Suppl, p. 1442-1447, 2008/09
  • Biosynthesis, remodelling and functions of mammalian GPI-anchored proteins: Recent progress, Taroh Kinoshita,Morihisa Fujita,Yusuke Maeda, Journal of Biochemistry, OXFORD UNIV PRESS, Vol. 144, No. 3, p. 287-294, 2008/09
  • Dolichol-phosphate mannose synthase: Structure, function and regulation, Yusuke Maeda,Taroh Kinoshita, Biochimica et Biophysica Acta - General Subjects, ELSEVIER SCIENCE BV, Vol. 1780, No. 6, p. 861-868, 2008/06
  • New strategy in development of antibiotics: GPI biosynthesis as a target, Taroh Kinoshita, The Japanese journal of antibiotics., Vol. 59, No. 2, p. 125-132, 2006/04
  • 発作性夜間ヘモグロビン尿症診療の参照ガイド, 小峰 光博,金倉 譲,西村 純一,木下 タロウ,井上 徳光,金丸 昭久,七島 勉,中熊 秀喜,川口 辰哉,中尾 眞二,朝長 万左男,小島 勢二,寺村 正尚,二宮 治彦, 臨床血液 = The Japanese Journal of Clinical Hematology, 一般社団法人 日本血液学会, Vol. 47, No. 3, p. 215-239, 2006/03/30
  • CHO Glycosylation Mutants: GPI Anchor, Yusuke Maeda,Hisashi Ashida,Taroh Kinoshita, Methods in Enzymology, Vol. 416, p. 182-205, 2006
  • Diagnosis and management of paroxysmal nocturnal hemoglobinuria, Charles Parker,Mitsuhiro Omine,Stephen Richards,Jun Ichi Nishimura,Monica Bessler,Russell Ware,Peter Hillmen,Lucio Luzzatto,Neal Young,Taroh Kinoshita,Wendell Rosse,Gerard Socié, Blood, Vol. 106, No. 12, p. 3699-3709, 2005/12/01
  • Paroxysmal nocturnal hemoglobinuria: mechanism of clonal expansion, Taroh Kinoshita,Ryoko Murakami,Tokumitsu Inoue, [Rinshō ketsueki] The Japanese journal of clinical hematology, The Japanese Society of Hematology, Vol. 46, No. 5, p. 317-323, 2005/05
  • Complement system in host defense, Kazuhito Ohishi,Taroh Kinoshita, Nippon rinsho. Japanese journal of clinical medicine, Vol. 63 Suppl 4, p. 263-268, 2005/04
  • Initial enzyme for glycosylphosphatidylnositol biosynthesis requires the seventh component PIG-Y, whose translation is initiated by internal ribosome entry, Y Murakami,Y Maeda,Y Hong,T Kinoshita, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 15, p. 186A-186A, 2004/11
  • Inositol Deacylation of Glycosylphosphatidylinositol-anchored Proteins Is Mediated by Mammalian PGAP1 and Yeast Bst1p, Satoshi Tanaka,Yusuke Maeda,Yuko Tashima,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 279, No. 14, p. 14256-14263, 2004/04
  • GPIアンカーと疾患 (第1土曜特集 糖鎖と疾患--ゲノムからポストゲノムへの展開) -- (各種病態と糖鎖), 前田 裕輔,木下 タロウ, 医学のあゆみ, 医歯薬出版, Vol. 207, No. 5, p. 355-360, 2003/11/01
  • GPIアンカー生合成酵素遺伝子 (糖鎖機能--第3の生命鎖) -- (糖転移酵素遺伝子・糖鎖関連遺伝子), 田中 聡,前田 裕輔,木下 タロウ, 蛋白質核酸酵素, 共立出版, Vol. 48, No. 8, p. 990-996, 2003/06
  • Biosynthesis of GPI-anchored proteins, Satoshi Tanaka,Yusuke Maeda,Taroh Kinoshita, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 48, No. 8 Suppl, p. 990-996, 2003/06
  • 抗原虫薬開発の標的としてのGPIアンカー生合成経路 (特集 パラサイトの分子戦略), 永宗 喜三郎,木下 タロウ, 蛋白質核酸酵素, 共立出版, Vol. 47, No. 1, p. 30-36, 2002/01
  • GPI biosynthetic pathway as a target for antiprotozoan drugs, Kisaburo Nagamune,Taroh Kinoshita, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 47, No. 1, p. 30-36, 2002/01
  • Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei, Kisaburo Nagamune,Tomoyoshi Nozaki,Yusuke Maeda,Kazuhito Ohishi,Toshihide Fukuma,Tatsuru Hara,Ralph T. Schwarz,Christine Sütterlin,Reto Brun,Howard Riezman,Taroh Kinoshita, Proceedings of the National Academy of Sciences of the United States of America, NATL ACAD SCIENCES, Vol. 97, No. 19, p. 10336-10341, 2000/09/12
  • Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2, Reika Watanabe,Yoshiko Murakami,Mina D. Marmor,Norimitsu Inoue,Yusuke Maeda,Jun Hino,Kenji Kangawa,Michael Julius,Taroh Kinoshita, EMBO Journal, OXFORD UNIV PRESS, Vol. 19, No. 16, p. 4402-4411, 2000/08/15
  • Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol, Yeongjin Hong,Yusuke Maeda,Reika Watanabe,Norimitsu Inoue,Kazuhito Ohishi,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 275, No. 27, p. 20911-20919, 2000/07/07
  • Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3, Yusuke Maeda,Satoshi Tanaka,Jun Hino,Kenji Kangawa,Taroh Kinoshita, EMBO Journal, OXFORD UNIV PRESS, Vol. 19, No. 11, p. 2475-2482, 2000/06/01
  • Gaa1p and Gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins, Kazuhito Ohishi,Norimitsu Inoue,Yusuke Maeda,Junji Takeda,Howard Riezman,Taroh Kinoshita, Molecular Biology of the Cell, AMER SOC CELL BIOLOGY, Vol. 11, No. 5, p. 1523-1533, 2000/05
  • Paroxysmal nocturnal hemoglobinuria, M. Kuwayama,T. Kinoshita,K. Ohishi, Ryōikibetsu shōkōgun shirīzu, No. 32, p. 236-238, 2000
  • Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol, Yeongjin Hong,Yusuke Maeda,Reika Watanabe,Kazuhito Ohishi,Michael Mishkind,Howard Riezman,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 274, No. 49, p. 35099-35106, 1999/12/03
  • Different roles of glycosylphosphatidylinositol in various hematopoietic cells as revealed by a mouse model of paroxysmal nocturnal hemoglobinuria, Y. Murakami,T. Kinoshita,Y. Maeda,T. Nakano,H. Kosaka,J. Takeda, Blood, AMER SOC HEMATOLOGY, Vol. 94, No. 9, p. 2963-2970, 1999/11/01
  • GPI1 stabilizes an enzyme essential in the first step of glycosylphosphatidylinositol biosynthesis, Yeongjin Hong,Kazuhito Ohishi,Reika Watanabe,Yuichi Endo,Yusuke Maeda,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 274, No. 26, p. 18582-18588, 1999/06/25
  • GPIアンカー蛋白質の生合成と欠損症 (脂質共有結合による蛋白質機能調節), 渡辺 玲香,木下 タロウ, 蛋白質核酸酵素, 共立出版, Vol. 44, No. 8, p. 1329-1336, 1999/06
  • Biosynthesis of GPI-anchored proteins and its deficiency, R. Watanabe,T. Kinoshita, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 44, No. 8 Suppl, p. 1329-1336, 1999/06
  • Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis, Reika Watanabe,Kazuhito Ohishi,Yusuke Maeda,Nobuo Nakamura,Taroh Kinoshita, Biochemical Journal, PORTLAND PRESS, Vol. 339, No. 1, p. 185-192, 1999/04
  • Developmental abnormalities of glycosylphosphatidylinositol-anchor- deficient embryos revealed by Cre/IoxP system, Masami Nozaki,Kazuhito Ohishi,Naoko Yamada,Taroh Kinoshita,Andras Nagy,Junji Takeda, Laboratory Investigation, LIPPINCOTT WILLIAMS & WILKINS, Vol. 79, No. 3, p. 293-299, 1999/03
  • Erratum: Analysis of PIG-A gene in a patient who developed a reciprocal translocation of chromosome 12 and paroxysmal nocturnal hemoglobinuria during follow-up of aplastic anemia (American Journal of Hematology (1996) 51 (229- 233)), J. I. Nishimura,N. Inoue,Y. Azenishi,T. Akaogi,M. Shibano,K. Kawagoe,E. Ueda,T. Machii,J. Takeda,T. Kinoshita,T. Kitani, American Journal of Hematology, WILEY-LISS, Vol. 61, No. 4, p. 277-277, 1999
  • Paroxysmal nocturnal hemoglobinuria: An acquired genetic disease, Jun Ichi Nishimura,Yoshiko Murakami,Taroh Kinoshita, American Journal of Hematology, WILEY-LISS, Vol. 62, No. 3, p. 175-182, 1999
  • Genes involved in GPI-anchor biosynthesis, Y. Maeda,T. Kinoshita, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 43, No. 16 Suppl, p. 2410-2417, 1998/12
  • DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: Correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate, Yusuke Maeda,Shuichiro Tomita,Reika Watanabe,Kazuhito Ohishi,Taroh Kinoshita, EMBO Journal, WILEY-BLACKWELL, Vol. 17, No. 17, p. 4920-4929, 1998/09/01
  • Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene, Yousuke Takahama,Kazuhito Ohishi,Yayoi Tokoro,Takehiko Sugawara,Yasuhide Yoshimura,Masaru Okabe,Taroh Kinoshita,Junji Takeda, European Journal of Immunology, WILEY-V C H VERLAG GMBH, Vol. 28, No. 7, p. 2159-2166, 1998/07
  • Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis, Christine Sütterlin,M. Victoria Escribano,Peter Gerold,Yusuke Maeda,Maria J. Mazon,Taroh Kinoshita,Ralph T. Schwarz,Howard Riezman, Biochemical Journal, PORTLAND PRESS, Vol. 332, No. 1, p. 153-159, 1998/05/15
  • A homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cells, Shuichiro Tomita,Norimitsu Inoue,Yusuke Maeda,Kazuhito Ohishi,Junji Takeda,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 273, No. 15, p. 9249-9254, 1998/04
  • The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1, Reika Watanabe,Norimitsu Inoue,Barbara Westfall,Christopher H. Taron,Peter Orlean,Junji Takeda,Taroh Kinoshita, EMBO Journal, OXFORD UNIV PRESS, Vol. 17, No. 4, p. 877-885, 1998/02/04
  • Structures and chromosomal localizations of the glycosylphosphatidylinositol synthesis gene PIGC and its pseudogene PIGCP1, Yeongjin Hong,Kazuhito Ohishi,Norimitsu Inoue,Yuichi Endo,Teizo Fujita,Junji Takeda,Taroh Kinoshita, Genomics, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 44, No. 3, p. 347-349, 1997/09/15
  • GPI-Anchor synthesis in mammalian cells: Genes, their products, and a deficiency, Taroh Kinoshita,Kazuhito Ohishi,Junji Takeda, Journal of Biochemistry, JAPANESE BIOCHEMICAL SOC, Vol. 122, No. 2, p. 251-257, 1997/08
  • Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development, Masahito Tarutani,Satoshi Itami,Masaru Okabe,Masahito Ikawa,Tadashi Tezuka,Kunihiko Yoshikawa,Taroh Kinoshita,Junji Takeda, Proceedings of the National Academy of Sciences of the United States of America, NATL ACAD SCIENCES, Vol. 94, No. 14, p. 7400-7405, 1997/07/08
  • Expression cloning of PIG-L, a candidate N- acetylglucosaminylphosphatidylinositol deacetylase, Nobuo Nakamura,Norimitsu Inoue,Reika Watanabe,Minoru Takahashi,Junji Takeda,Victoria L. Stevens,Taroh Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 25, p. 15834-15840, 1997/06/20
  • A patient with paroxysmal nocturnal hemoglobinuria bearing four independent PIG-A mutant clones, Jun Ichi Nishimura,Norimitsu Inoue,Hiroshi Wada,Etsuko Ueda,Patcharin Pramoonjago,Toshiyuki Hirota,Takashi Machii,Takashi Kageyama,Akihisa Kanamaru,Junji Takeda,Taroh Kinoshita,Teruo Kitani, Blood, W B SAUNDERS CO, Vol. 89, No. 9, p. 3470-3476, 1997/05/01
  • Molecular cloning of a pig homologue of membrane cofactor protein (CD46), Kohji Toyomura,Tatsuya Fujimura,Hiroshi Murakami,Tohru Natsume,Tamotsu Shigehisa,Norimitsu Inoue,Junji Takeda,Taroh Kinoshita, International Immunology, OXFORD UNIV PRESS, Vol. 9, No. 6, p. 869-876, 1997
  • PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2, Norimitsu Inoue,Reika Watanabe,Junji Takeda,Taroh Kinoshita, Biochemical and Biophysical Research Communications, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 226, No. 1, p. 193-199, 1996/09/04
  • PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor, M. Takahashi,N. Inoue,K. Ohishi,Y. Maeda,N. Nakamura,Y. Endo,T. Fujita,J. Takeda,T. Kinoshita, EMBO Journal, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 15, No. 16, p. 4254-4261, 1996/08/15
  • Cloning and characterization of the murine GPI anchor synthesis gene Pigf, a homologue of the human PIGF gene, Kazuhito Ohishi,Yasuyuki Kurimoto,Norimitsu Inoue,Yuichi Endo,Junji Takeda,Taroh Kinoshita, Genomics, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 34, No. 3, p. 340-346, 1996/06/15
  • Glycosylphosphatidylinositol-anchor-deficient mice: Implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria, Kazuyoshi Kawagoe,Daisuke Kitamura,Masaru Okabe,Ichiro Taniuchi,Masahito Ikawa,Takeshi Watanabe,Taroh Kinoshita,Junji Takeda, Blood, W B SAUNDERS CO, Vol. 87, No. 9, p. 3600-3606, 1996/05/01
  • Analysis of PIG-A gene in a patient who developed reciprocal translocation of chromosome 12 and paroxysmal nocturnal hemoglobinuria during follow-up of aplastic anemia, Jun Ichi Nishimura,Norimitsu Inoue,Yasuhiko Azenishi,Toshiyuki Hirota,Teruaki Akaogi,Masaru Shibano,Kazuyoshi Kawagoe,Etsuko Ueda,Takashi Machii,Junji Takeda,Taroh Kinoshita,Teruo Kitani, American Journal of Hematology, WILEY-LISS, Vol. 51, No. 3, p. 229-233, 1996/03
  • PIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulum, Reika Watanabe,Taroh Kinoshita,Ryuichi Masaki,Akitsugu Yamamoto,Junji Takedat,Norimitsu Inoue, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 271, No. 43, p. 26868-26875, 1996
  • Role of phosphatidylinositol-linked proteins in paroxysmal nocturnal hemoglobinuria pathogenesis, Taroh Kinoshita,Norimitsu Inoue,Junji Takeda, Annual Review of Medicine, ANNUAL REVIEWS INC, Vol. 47, p. 1-10, 1996
  • Paroxysmal nocturnal hemoglobinuria and complement regulatory factors, T. Kinoshita, Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology, Vol. 18, No. 6, p. 634-636, 1995/12
  • Structure and chromosomal localization of the GPI-anchor synthesis gene PIGF and its pseudogene ψPIGF, Kazuhito Ohishi,Norimitsu Inoue,Yuichi Endo,Teizo Fujita,Junji Takeda,Taroh Kinoshita, Genomics, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 29, No. 3, p. 804-807, 1995/10
  • Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria, Patcharin Pramoonjago,Wanchai Wanachiwanawin,Sriprapa Chinprasertsak,Kovit Pattanapanayasat,Junji Takeda,Taroh Kinoshita, Blood, W B SAUNDERS CO, Vol. 86, No. 5, p. 1736-1739, 1995/09/01
  • GPI-anchor biosynthesis, Junji Takeda,Taroh Kinoshita, Trends in Biochemical Sciences, ELSEVIER SCI LTD, Vol. 20, No. 9, p. 367-371, 1995/09
  • Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria, Norio Yamada,Toshio Miyata,Kenji Maeda,Teruo Kitani,Junji Takeda,Taroh Kinoshita, Blood, W B SAUNDERS CO, Vol. 85, No. 4, p. 885-892, 1995/02/15
  • Defective glycosyl phospharidylinositol anchor synthesis and paroxysmal nocturnal hemoglobinuria, Taroh Kinoshita,Norimitsu Inoue,Junji Takeda, Advances in Immunology, ACADEMIC PRESS INC, Vol. 60, p. 57-103, 1995
  • GPIアンカ-の生合成, 木下 タロウ,竹田 潤二, 生化学, 日本生化学会, Vol. 66, No. 12, p. p1471-1487, 1994/12
  • Biosynthesis of the GPI anchor, T. Kinoshita,J. Takeda, Seikagaku. The Journal of Japanese Biochemical Society, Vol. 66, No. 12, p. 1471-1487, 1994/12
  • Molecular Cloning of Murine Pig-a, a Gene for GPI-Anchor Biosynthesis, and Demonstration of Interspecies Conservation of Its Structure, Function, and Genetic Locus, Kazuyoshi Kawagoe,Junji Takeda,Yuichi Endo,Taroh Kinoshita, Genomics, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 23, No. 3, p. 566-574, 1994/10
  • The genetic defect of PNH., T. Kinoshita, Clinical and experimental immunology, Vol. 97 Suppl 2, p. 3-4, 1994/08
  • Characterization of genomic PIG-A gene: A gene for glycosylphosphatidylinositol-anchor biosynthesis and paroxysmal nocturnal hemoglobinuria, Yoshiyasu Iida,Junji Takeda,Toshio Miyata,Norimitsu Inoue,Junichi Nishimura,Teruo Kitani,Kenji Maeda,Taroh Kinoshita, Blood, W B SAUNDERS CO, Vol. 83, No. 11, p. 3126-3131, 1994/06/01
  • Abnormalities of PIG-A Transcripts in Granulocytes from Patients with Paroxysmal Nocturnal Hemoglobinuria, Toshio Miyata,Norio Yamada,Yoshiyasu Iida,Junichi Nishimura,Junji Takeda,Teruo Kitani,Taroh Kinoshita, New England Journal of Medicine, MASS MEDICAL SOC, Vol. 330, No. 4, p. 249-255, 1994/01/27
  • GPI-anchor synthesis, T. Kinoshita,J. Takeda, Parasitology Today, ELSEVIER SCI LTD, Vol. 10, No. 4, p. 139-143, 1994
  • Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene, M. Bessler,P. J. Mason,P. Hillmen,T. Miyata,N. Yamada,J. Takeda,L. Luzzatto,T. Kinoshita, EMBO Journal, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 13, No. 1, p. 110-117, 1994
  • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria, Junji Takeda,Toshio Miyata,Kazuyoshi Kawagoe,Yoshiyasu Iida,Yuichi Endo,Teizo Fujita,Minoru Takahashi,Teruo Kitani,Taroh Kinoshita, Cell, CELL PRESS, Vol. 73, No. 4, p. 703-711, 1993/05/21
  • GPI-anchored proteins and paroxysmal nocturnal hemoglobinuria, T. Kinoshita,J. Takeda, Nippon saikingaku zasshi. Japanese journal of bacteriology, Vol. 48, No. 3, p. 533-539, 1993/05
  • Recent advances in research on paroxysmal nocturnal hemoglobinuria, T. Kinoshita, [Rinshō ketsueki] The Japanese journal of clinical hematology, Vol. 34, No. 5, p. 529-536, 1993/05
  • DEFICIENT BIOSYNTHESIS OF N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL, THE 1ST INTERMEDIATE OF GLYCOSYL PHOSPHATIDYLINOSITOL ANCHOR BIOSYNTHESIS, IN CELL-LINES ESTABLISHED FROM PATIENTS WITH PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA, M TAKAHASHI,J TAKEDA,S HIROSE,R HYMAN,N INOUE,T MIYATA,E UEDA,T KITANI,ME MEDOF,T KINOSHITA, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 177, No. 2, p. 517-521, 1993/02
  • Deficient biosynthesis of N-acetylglucosaminyl-phosphatidylinositol, the first intermediate of glycosyl phosphatidylinositol anchor biosynthesis, in cell lines established from patients with paroxysmal nocturnal hemoglobinuria, Minoru Takahashi,Junji Takeda,Shinichi Hirose,Robert Hyman,Norimitsu Inoue,Toshio Miyata,Etsuko Ueda,Teruo Kitani,M. Edward Medof,Taroh Kinoshita, Journal of Experimental Medicine, Vol. 177, No. 2, p. 517-521, 1993/02/01
  • The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis, Toshio Miyata,Junji Takeda,Yoshiyasu Iida,Norio Yamada,Norimitsu Inoue,Minoru Takahashi,Kenji Maeda,Teruo Kitani,Taroh Kinoshita, Science, AMER ASSOC ADVANCEMENT SCIENCE, Vol. 259, No. 5099, p. 1318-1320, 1993
  • The evolution of mouse and human complement C3-binding proteins: divergence of form but conservation of function, V. Michael Holers,Taroh Kinoshita,Hector Molina, Immunology Today, Vol. 13, No. 6, p. 231-236, 1992
  • Covalent binding of C3b to C4b within the classical complement pathway C5 convertase. Determination of amino acid residues involved in ester linkage formation, Y. U. Kim,M. C. Carroll,D. E. Isenman,M. Nonaka,P. Pramoonjago,J. Takeda,K. Inoue,T. Kinoshita, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 267, No. 6, p. 4171-4176, 1992
  • Biology of complement: the overture, Taroh Kinoshita, Immunology Today, ELSEVIER SCI LTD, Vol. 12, No. 9, p. 291-295, 1991/09
  • In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody, Birgitta Heyman,Erik J. Wiersma,Taroh Kinoshita, Journal of Experimental Medicine, ROCKEFELLER UNIV PRESS, Vol. 172, No. 2, p. 665-668, 1990/08/01
  • Characterization of murine complement receptor type 2 and its immunological cross-reactivity with type 1 receptor, Taroh Kinoshita,George Thyphronitis,George C. Tsokos,Fred D. Finkelman,Kyongsu Hong,Hiroshi Sakai,Kozo Inoue, International Immunology, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 2, No. 7, p. 651-659, 1990/07
  • Localization of the covalent C3b-binding site on C4b within the complement classical pathway C5 convertase, C4b2a3b, H. Kozono,T. Kinoshita,Y. U. Kim,Y. Takata-Kozono,S. Tsunasawa,F. Sakiyama,J. Takeda,K. Hong,K. Inoue, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 265, No. 24, p. 14444-14449, 1990
  • Monoclonal antibodies to mouse complement receptor type 1 (CR1). Their use in a distribution study showing that mouse erythrocytes and platelets are CR1-negative, T. Kinoshita,J. Takeda,K. Hong,H. Kozono,H. Sakai,K. Inoue, Journal of Immunology, AMER ASSOC IMMUNOLOGISTS, Vol. 140, No. 9, p. 3066-3072, 1988
  • C5 convertase of the alternative complement pathway: Covalent linkage between two C3b molecules within the trimolecular complex enzyme, T. Kinoshita,Y. Takata,H. Kozono,J. Takeda,K. Hong,K. Inoue, Journal of Immunology, AMER ASSOC IMMUNOLOGISTS, Vol. 141, No. 11, p. 3895-3901, 1988
  • Covalent association of C3b with C4b within C5 convertase of the classical complement pathway, Yuko Takata,Taroh Kinoshita,Haruo Kozono,Junji Takeda,Etsuko Tanaka,Kyongsu Hong,Kozo Inoue, Journal of Experimental Medicine, ROCKEFELLER UNIV PRESS, Vol. 165, No. 6, p. 1494-1507, 1987/06/01
  • Distribution of decay-accelerating factor in the peripheral blood of normal individuals and patients with paroxysmal nocturnal hemoglobinuria, Taroh Kinoshita,M. Edward Medof,Robert Silber,Victor Nussenzweig, Journal of Experimental Medicine, ROCKEFELLER UNIV PRESS, Vol. 162, No. 1, p. 75-92, 1985/07/01
  • Inhibition of complement activation on the surface of cells after incorporation of Decay-Accelerating Factor (DAF) into their membranes, M. Edward Medof,Taroh Kinoshita,Victor Nussenzweig, Journal of Experimental Medicine, ROCKEFELLER UNIV PRESS, Vol. 160, No. 5, p. 1558-1578, 1984/11/01

Publications

  • Essentials of glycobiology, Varki, Aji,Cummings, Richard D,Esko, Jeffrey,Stanley, Pamela,Hart, Gerald W,Aebi, Markus,Mohnen, Debra,Kinoshita, Taroh,Packer, Nicolle H,Prestegard, James H,Schnaar, Ronald L,Seeberger, P.H, Cold Spring Harbor Laboratory Press, ISBN:9781621824213, 2022/05

Awards

  • Karl Meyer Lectureship Award, Society for Glycobiology, 2023/11
  • 太田原豊一賞, 2022
  • 早石修記念賞, 2021
  • 紫綬褒章, 2018
  • ヒト免疫研究賞, 日本免疫学会, 2017
  • Takeda Medical Prize, 2017
  • IGO Award 2015, International Glycoconjugate Organization, 2015
  • 文部科学大臣表彰（科学技術賞：研究部門）, 文部科学省, 2010
  • 大阪科学賞（第19回）, 2001

Committee Memberships

  • 生体防御学会, 運営委員, 1991 - 2024/03
  • 国際補体学会(International Complement Society), 理事, 2000 - 2004
  • 日本免疫学会, 運営委員, 1989 -