keyword Genome editing
日本ゲノム編集学会
日本分子生物学会
Life sciences / Genomics /
2019 Sanofi-Cell Research Outstanding Paper Award
Sanofi-Cell Research 2020
Top young investigator abstract
Keiichiro Suzuki 2016 FASEB Science Research conference in the Lisbon 2016/06
Best young investigator abstract
Keiichiro Suzuki 2014 FASEB Science Research conference in the Bahamas 2014/06
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction
Suzuki Keiichiro, Yamamoto Mako, Hernandez-Benitez Reyna, Li Zhe, Wei Christopher, Devi Soligalla Rupa, Aizawa Emi, Hatanaka Fumiyuki, Kurita Masakazu, Reddy Pradeep, Ocampo Alejandro, Hishida Tomoaki, Sakurai Masahiro, Nemeth Amy N, Nunez Delicado Estrella, Campistol Josep M, Magistretti Pierre, Guillen Pedro, Esteban Concepcion Rodriguez, Gong Jianhui, Yuan Yilin, Gu Ying, Liu Guang-Hui, Lopez-Otin Carlos, Wu Jun, Zhang Kun, Belmonte Juan, Carlos Izpisua
CELL RESEARCH Vol. 29 No. 10 p. 804-819 2019/10 Research paper (scientific journal)
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
Keiichiro Suzuki, Yuji Tsunekawa, Reyna Hernandez-Benitez, Jun Wu, Jie Zhu, Euiseok J. Kim, Fumiyuki Hatanaka, Mako Yamamoto, Toshikazu Araoka, Zhe Li, Masakazu Kurita, Tomoaki Hishida, Mo Li, Emi Aizawa, Shicheng Guo, Song Chen, April Goebl, Rupa Devi Soligalla, Jing Qu, Tingshuai Jiang, Xin Fu, Maryam Jafari, Concepcion Rodriguez Esteban, W. Travis Berggern, Jeronimo Lajara, Estrella Nunez-Delicado, Pedro Guillen, Josep M. Campistol, Fumio Matsuzaki, Guang-Hui Liu, Pierre Magistretti, Kun Zhang, Edward M. Callaway, Kang Zhang, Juan Carlos Izpisua Belmonte
NATURE Vol. 540 No. 7631 p. 144-+ 2016/12 Research paper (scientific journal)
Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones
Keiichiro Suzuki, Chang Yu, Jing Qu, Mo Li, Xiaotian Yao, Tingting Yuan, April Goebl, Senwei Tang, Ruotong Ren, Emi Aizawa, Fan Zhang, Xiuling Xu, Rupa Devi Soligalla, Feng Chen, Jessica Kim, Na Young Kim, Hsin-Kai Liao, Chris Benner, Concepcion Rodriguez Esteban, Yabin Jin, Guang-Hui Liu, Yingrui Li, Juan Carlos Izpisua Belmonte
CELL STEM CELL Vol. 15 No. 1 p. 31-36 2014/07 Research paper (scientific journal)
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2
Guang-Hui Liu, Jing Qu, Keiichiro Suzuki, Emmanuel Nivet, Mo Li, Nuria Montserrat, Fei Yi, Xiuling Xu, Sergio Ruiz, Weiqi Zhang, Ulrich Wagner, Audrey Kim, Bing Ren, Ying Li, April Goebl, Jessica Kim, Rupa Devi Soligalla, Ilir Dubova, James Thompson, John Yates, Concepcion Rodriguez Esteban, Ignacio Sancho-Martinez, Juan Carlos Izpisua Belmonte
NATURE Vol. 491 No. 7425 p. 603-607 2012/11 Research paper (scientific journal)
Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes.
Jun Hirose, Emi Aizawa, Shogo Yamamoto, Shigenori Iwai, Keiichiro Suzuki
Communications medicine Vol. 5 No. 1 p. 269-269 2025/07/09 Research paper (scientific journal)
Author Correction: PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype.
Shunlei Duan, Guohong Yuan, Xiaomeng Liu, Ruotong Ren, Jingyi Li, Weizhou Zhang, Jun Wu, Xiuling Xu, Lina Fu, Ying Li, Jiping Yang, Weiqi Zhang, Ruijun Bai, Fei Yi, Keiichiro Suzuki, Hua Gao, Concepcion Rodriguez Esteban, Chuanbao Zhang, Juan Carlos Izpisua Belmonte, Zhiguo Chen, Xiaomin Wang, Tao Jiang, Jing Qu, Fuchou Tang, Guang-Hui Liu
Nature communications Vol. 16 No. 1 p. 5353-5353 2025/06/20
Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines.
Nayara Sousa da Silva, Agnieszka D'Antonio-Chronowska, Reyna Hernandez-Benitez, Angelina Rose McCarron, Esra Karaca, Kai Fang, Juan Carlos Izpisua Belmonte, Athanasia D Panopoulos, Keiichiro Suzuki, Kelly A Frazer
Stem cell research Vol. 87 p. 103755-103755 2025/06/18 Research paper (scientific journal)
Senescence-resistant human mesenchymal progenitor cells counter aging in primates.
Jinghui Lei, Zijuan Xin, Ning Liu, Taixin Ning, Ying Jing, Yicheng Qiao, Zan He, Mengmeng Jiang, Yuanhan Yang, Zhiyi Zhang, Liyun Zhao, Jingyi Li, Dongliang Lv, Yupeng Yan, Hui Zhang, Lingling Xiao, Baohu Zhang, Haoyan Huang, Shuhui Sun, Fangshuo Zheng, Xiaoyu Jiang, Huifen Lu, Xueda Dong, Shasha Yue, Chencan Ma, Jichen Shuai, Zhejun Ji, Feifei Liu, Yanxia Ye, Kaowen Yan, Qinchao Hu, Gang Xu, Qian Zhao, Ruochen Wu, Yusheng Cai, Yanling Fan, Yaobin Jing, Qiaoran Wang, Pradeep Reddy, Xiaoyong Lu, Zikai Zheng, Beibei Liu, Amin Haghani, Shuai Ma, Keiichiro Suzuki, Concepcion Rodriguez Esteban, Jiayin Yang, Moshi Song, Steve Horvath, Weiqi Zhang, Wei Li, Andy Peng Xiang, Lan Zhu, Xiaobing Fu, Guoguang Zhao, Juan Carlos Izpisua Belmonte, Jing Qu, Si Wang, Guang-Hui Liu
Cell 2025/06/13 Research paper (scientific journal)
Author Correction: Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.
Guang-Hui Liu, Basam Z Barkho, Sergio Ruiz, Dinh Diep, Jing Qu, Sheng-Lian Yang, Athanasia D Panopoulos, Keiichiro Suzuki, Leo Kurian, Christopher Walsh, James Thompson, Stephanie Boue, Ho Lim Fung, Ignacio Sancho-Martinez, Kun Zhang, John Yates Iii, Juan Carlos Izpisua Belmonte
Nature Vol. 640 No. 8060 2025/04
Perspectives on the essence and drivers of aging.
Haim Y Cohen, Vera Gorbunova, Steve Horvath, Brian K Kennedy, Wei Li, João Pedro de Magalhães, Andrei Seluanov, Moshi Song, Keiichiro Suzuki
Life medicine Vol. 4 No. 2 2025/04
Dynamic WNT signaling controls differentiation of hematopoietic progenitor cells from human pluripotent stem cells.
Mo Li, Keiichiro Suzuki, Mengge Wang, Christopher Benner, Manching Ku, Li Ma, Ladan Kobari, Na Young Kim, Nuria Montserrat, Chan-Jung Chang, Guanghui Liu, Jing Qu, Jinna Xu, Yingzi Zhang, Emi Aizawa, Jun Wu, Luc Douay, Concepcion Rodriguez Esteban, Juan Carlos Izpisua Belmonte
Science China. Life sciences 2025/03/11 Research paper (scientific journal)
Lipid Nanoparticles Enable Efficient In Vivo DNA Knock-In via HITI-Mediated Genome Editing
Jun Hirose, Emi Aizawa, Shogo Yamamoto, Mingyao Xu, Shigenori Iwai, Keiichiro Suzuki
Biomolecules Vol. 14 No. 12 p. 1558-1558 2024/12/06 Research paper (scientific journal)
Publisher: MDPI AG
Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa.
Akishi Onishi, Yuji Tsunekawa, Michiko Mandai, Aiko Ishimaru, Yoko Ohigashi, Junki Sho, Kazushi Yasuda, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Fumio Matsuzaki, Masayo Takahashi
Investigative ophthalmology & visual science Vol. 65 No. 13 p. 38-38 2024/11/04 Research paper (scientific journal)
Comprehensive High-Depth Proteomic Analysis of Plasma Extracellular Vesicles Containing Preparations in Rett Syndrome
Sho Hagiwara, Tadashi Shiohama, Satoru Takahashi, Masaki Ishikawa, Yusuke Kawashima, Hironori Sato, Daisuke Sawada, Tomoko Uchida, Hideki Uchikawa, Hironobu Kobayashi, Megumi Shiota, Shin Nabatame, Keita Tsujimura, Hiromichi Hamada, Keiichiro Suzuki
Biomedicines Vol. 12 No. 10 p. 2172-2172 2024/09/24 Research paper (scientific journal)
Publisher: MDPI AG
Optimization of an adeno-associated viral vector for epidermal keratinocytes in vitro and in vivo.
Qi Shen, Shogo Suga, Yuta Moriwaki, Zening Du, Emi Aizawa, Mutsumi Okazaki, Juan Carlos Izpisua Belmonte, Yusuke Hirabayashi, Keiichiro Suzuki, Masakazu Kurita
Journal of dermatological science Vol. 115 No. 3 p. 101-110 2024/09 Research paper (scientific journal)
Endonuclease Q as a robust enhancer for nucleic acid amplification.
Miyako Shiraishi, Noboru Nabeshima, Keiichiro Suzuki, Masatoshi Fujita, Shigenori Iwai
Analytical biochemistry Vol. 692 p. 115569-115569 2024/09 Research paper (scientific journal)
Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing.
Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, Jingting Yu, Yuta Takahashi, Akihisa Sakamoto, Javier Prieto, Maxim Shokhirev, Estrella Nuñez Delicado, Concepcion Rodriguez Esteban, Juan Carlos Izpisua Belmonte
Nature communications Vol. 15 No. 1 p. 6191-6191 2024/07/24 Research paper (scientific journal)
Rett症候群における高深度プロテオーム解析による新規バイオマーカーの検索
萩原 翔, 塩浜 直, 高橋 悟, 佐藤 裕範, 川島 祐介, 澤田 大輔, 内田 智子, 斎藤 千尋, 小林 宏伸, 塩田 恵, 濱田 洋通, 鈴木 啓一郎
脳と発達 Vol. 56 No. Suppl. p. S261-S261 2024/05
Publisher: (一社)日本小児神経学会Transduction and Genome Editing of the Heart with Adeno-Associated Viral Vectors Loaded onto Electrospun Polydioxanone Nonwoven Fabrics
Kotoko Furuno, Keiichiro Suzuki, Shinji Sakai
Biomolecules Vol. 14 No. 4 2024/04/22 Research paper (scientific journal)
Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo.
Meng Liu, Chao Zhang, Ximing Gong, Tian Zhang, Michelle Mulan Lian, Elaine Guo Yan Chew, Angelysia Cardilla, Keiichiro Suzuki, Huamin Wang, Yuan Yuan, Yan Li, Mihir Yogesh Naik, Yixuan Wang, Bingrui Zhou, Wei Ze Soon, Emi Aizawa, Pin Li, Jian Hui Low, Moses Tandiono, Enrique Montagud, Daniel Moya-Rull, Concepcion Rodriguez Esteban, Yosu Luque, Mingliang Fang, Chiea Chuen Khor, Nuria Montserrat, Josep M Campistol, Juan Carlos Izpisua Belmonte, Jia Nee Foo, Yun Xia
Cell stem cell Vol. 31 No. 1 p. 52-70 2024/01/04 Research paper (scientific journal)
Efficient workflow for validating homology-independent targeted integration-mediated gene insertion in rod photoreceptor cells to treat dominant-negative mutations causing retinitis pigmentosa
Akishi Onishi, Yuji Tsunekawa, Michiko Mandai, Aiko Ishimaru, Yoko Ohigashi, Junki Sho, Kazushi Yasuda, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Fumio Matsuzaki, Masayo Takahashi
2023/11/09
Local delivery of adeno-associated viral vectors with electrospun gelatin nanofiber mats.
Kotoko Furuno, Kelum Chamara Manoj Lakmal Elvitigala, Keiichiro Suzuki, Shinji Sakai
Journal of biomedical materials research. Part B, Applied biomaterials Vol. 112 No. 1 2023/10/30 Research paper (scientific journal)
Modeling the marmoset brain using embryonic stem cell-derived cerebral assembloids
Tomoki Kodera, Ryosuke F. Takeuchi, Sara Takahashi, Keiichiro Suzuki, Hidetoshi Kassai, Atsu Aiba, Seiji Shiozawa, Hideyuki Okano, Fumitaka Osakada
Biochemical and Biophysical Research Communications Vol. 657 p. 119-127 2023/05 Research paper (scientific journal)
miR-514a promotes neuronal development in human iPSC-derived neurons.
Yuichi Akaba, Satoru Takahashi, Keiichiro Suzuki, Kenjiro Kosaki, Keita Tsujimura
Frontiers in cell and developmental biology Vol. 11 p. 1096463-1096463 2023 Research paper (scientific journal)
Gelatin-Based Electrospun Nanofibers Cross-Linked Using Horseradish Peroxidase for Plasmid DNA Delivery
Kotoko Furuno, Keiichiro Suzuki, Shinji Sakai
Biomolecules Vol. 12 No. 11 2022/11/04 Research paper (scientific journal)
Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano, Mengge Wang, Muhammad Tehseen, Lorena V Cortés-Medina, James J Moresco, Sarah Dunn, Reyna Hernandez-Benitez, Tomoaki Hishida, Na Young Kim, Manal M Andijani, Chongwei Bi, Manching Ku, Yuta Takahashi, Jinna Xu, Jinsong Qiu, Ling Huang, Christopher Benner, Emi Aizawa, Jing Qu, Guang-Hui Liu, Zhongwei Li, Fei Yi, Yanal Ghosheh, Changwei Shao, Maxim Shokhirev, Patrizia Comoli, Francesco Frassoni, John R Yates 3rd, Xiang-Dong Fu, Concepcion Rodriguez Esteban, Samir Hamdan, Juan Carlos Izpisua Belmonte, Mo Li
Nature communications Vol. 13 No. 1 p. 5291-5291 2022/09/08
Gelatin nanofiber mats with Lipofectamine/plasmid DNA complexes for in vitro genome editing.
Kotoko Furuno, Keiichiro Suzuki, Shinji Sakai
Colloids and surfaces. B, Biointerfaces Vol. 216 p. 112561-112561 2022/08 Research paper (scientific journal)
Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano, Mengge Wang, Muhammad Tehseen, Lorena V Cortés-Medina, James J Moresco, Sarah Dunn, Reyna Hernandez-Benitez, Tomoaki Hishida, Na Young Kim, Manal M Andijani, Chongwei Bi, Manching Ku, Yuta Takahashi, Jinna Xu, Jinsong Qiu, Ling Huang, Christopher Benner, Emi Aizawa, Jing Qu, Guang-Hui Liu, Zhongwei Li, Fei Yi, Yanal Ghosheh, Changwei Shao, Maxim Shokhirev, Patrizia Comoli, Francesco Frassoni, John R Yates 3rd, Xiang-Dong Fu, Concepcion Rodriguez Esteban, Samir Hamdan, Mo Li, Juan Carlos Izpisua Belmonte
Nature communications Vol. 13 No. 1 p. 3646-3646 2022/06/25 Research paper (scientific journal)
Establishment of mouse model of inherited PIGO deficiency and therapeutic potential of AAV-based gene therapy.
Ryoko Kuwayama, Keiichiro Suzuki, Jun Nakamura, Emi Aizawa, Yoshichika Yoshioka, Masahito Ikawa, Shin Nabatame, Ken-Ichi Inoue, Yoshiari Shimmyo, Keiichi Ozono, Taroh Kinoshita, Yoshiko Murakami
Nature communications Vol. 13 No. 1 p. 3107-3107 2022/06/03
Editorial: Developmental models 2.0.
Alessandra Giorgetti, Ying Gu, Keiichiro Suzuki, Mo Li
Frontiers in cell and developmental biology Vol. 10 p. 1055139-1055139 2022 Research paper (scientific journal)
Gelatin-Based Electrospun Fibers Insolubilized by Horseradish Peroxidase-Catalyzed Cross-Linking for Biomedical Applications.
Kotoko Furuno, Jing Wang, Keiichiro Suzuki, Masaki Nakahata, Shinji Sakai
ACS omega Vol. 5 No. 33 p. 21254-21259 2020/08/25 Research paper (scientific journal)
Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction.
Si Wang, Zheying Min, Qianzhao Ji, Lingling Geng, Yao Su, Zunpeng Liu, Huifang Hu, Lixia Wang, Weiqi Zhang, Keiichiro Suzuiki, Yu Huang, Puyao Zhang, Tie-Shan Tang, Jing Qu, Yang Yu, Guang-Hui Liu, Jie Qiao
Protein & cell Vol. 11 No. 1 p. 1-22 2020/01 Research paper (scientific journal)
Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network.
Jian Hui Low, Pin Li, Elaine Guo Yan Chew, Bingrui Zhou, Keiichiro Suzuki, Tian Zhang, Michelle Mulan Lian, Meng Liu, Emi Aizawa, Concepcion Rodriguez Esteban, Kylie Su Mei Yong, Qingfeng Chen, Josep M Campistol, Mingliang Fang, Chiea Chuen Khor, Jia Nee Foo, Juan Carlos Izpisua Belmonte, Yun Xia
Cell stem cell Vol. 25 No. 3 p. 373-387 2019/09/05 Research paper (scientific journal)
Development of de novo epithelialization method for treatment of cutaneous ulcers.
Masakazu Kurita, Juan Carlos Izpisua Belmonte, Keiichiro Suzuki, Mutsumi Okazaki
Journal of dermatological science Vol. 95 No. 1 p. 8-12 2019/07 Research paper (scientific journal)
Induced pluripotent stem cell-based modeling of mutant LRRK2-associated Parkinson's Disease.
Weykopf B, Haupt S, Jungverdorben J, Flitsch LJ, Hebisch M, Liu G, Suzuki K, Belmonte JCI, Peitz M, Blaess S, Till A, Brüstle O
The European journal of neuroscience 2019/01 Research paper (scientific journal)
FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration.
Yan P, Li Q, Wang L, Lu P, Suzuki K, Liu Z, Lei J, Li W, He X, Wang S, Ding J, Chan P, Zhang W, Song M, Izpisua Belmonte JC, Qu J, Tang F, Liu GH, Senior author
Cell stem cell 2019/01 Research paper (scientific journal)
In vivo reprogramming of wound-resident cells generates skin epithelial tissue.
Kurita M, Araoka T, Hishida T, O'Keefe DD, Takahashi Y, Sakamoto A, Sakurai M, Suzuki K, Wu J, Yamamoto M, Hernandez-Benitez R, Ocampo A, Reddy P, Shokhirev MN, Magistretti P, Núñez Delicado E, Eto H, Harii K, Izpisua Belmonte JC
Nature Vol. 561 No. 7722 p. 243-247 2018/09 Research paper (scientific journal)
Large deletions induced by Cas9 cleavage Reply
Ma Hong, Marti-Gutierrez Nuria, Park Sang-Wook, Wu Jun, Hayama Tomonari, Darby Hayley, Van Dyken Crystal, Li Ying, Koski Amy, Liang Dan, Suzuki Keiichiro, Gu Ying, Gong Jianhui, Xu Xun, Ahmed Riffat, Lee Yeonmi, Kang Eunju, Ji Dongmei, Park A-Reum, Kim Daesik, Kim Sang-Tae, Heitner Stephen B, Battaglia David, Krieg Sacha A, Lee David M, Wu Diana H, Wolf Don P, Amato Paula, Kaul Sanjiv, Belmonte Juan, Carlos Izpisua, Kim Jin-Soo, Mitalipov Shoukhrat
NATURE Vol. 560 No. 7717 p. E10-E23 2018/08/09 Research paper (scientific journal)
Ma et al. reply.
Hong Ma, Nuria Marti-Gutierrez, Sang-Wook Park, Jun Wu, Tomonari Hayama, Hayley Darby, Crystal Van Dyken, Ying Li, Amy Koski, Dan Liang, Keiichiro Suzuki, Ying Gu, Jianhui Gong, Xun Xu, Riffat Ahmed, Yeonmi Lee, Eunju Kang, Dongmei Ji, A-Reum Park, Daesik Kim, Sang-Tae Kim, Stephen B Heitner, David Battaglia, Sacha A Krieg, David M Lee, Diana H Wu, Don P Wolf, Paula Amato, Sanjiv Kaul, Juan Carlos Izpisua Belmonte, Jin-Soo Kim, Shoukhrat Mitalipov
Nature Vol. 560 No. 7717 2018/08 Research paper (scientific journal)
Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome
Zeming Wu, Weiqi Zhang, Moshi Song, Wei Wang, Gang Wei, Wei Li, Jinghui Lei, Yu Huang, Yanmei Sang, Piu Chan, Chang Chen, Jing Qu, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Guang-Hui Liu
Protein and Cell Vol. 9 No. 4 p. 333-350 2018/04/01 Research paper (scientific journal)
Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts
Yanina Soledad Bogliotti, Jun Wu, Marcela Vilarino, Daiji Okamura, Delia Alba Soto, Cuiqing Zhong, Masahiro Sakurai, Rafael Vilar Sampaio, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Pablo Juan Ross
Proceedings of the National Academy of Sciences of the United States of America Vol. 115 No. 9 p. 2090-2095 2018/02/27 Research paper (scientific journal)
In vivo genome editing via the HITI method as a tool for gene therapy
Keiichiro Suzuki, Juan Carlos Izpisua Belmonte
Journal of Human Genetics Vol. 63 No. 2 p. 157-164 2018/02/01 Research paper (scientific journal)
神経科学研究技術の最前線 新規遺伝子標的システムの開発(Developing de novo gene targeting systems)
恒川 雄二, Terhune Raymond, 鈴木 啓一郎, Kim Euiseok, Callaway Edward, Belmonte Juan Carlos, 松崎 文雄
生命科学系学会合同年次大会 Vol. 2017年度 p. [3AS09-3] 2017/12
Publisher: 生命科学系学会合同年次大会運営事務局Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding
Jiping Yang, Jingyi Li, Keiichiro Suzuki, Xiaomeng Liu, Jun Wu, Weiqi Zhang, Ruotong Ren, Weizhou Zhang, Piu Chan, Juan Carlos Izpisua Belmonte, Jing Qu, Fuchou Tang, Guang-Hui Liu
CELL RESEARCH Vol. 27 No. 9 p. 1178-1181 2017/09 Research paper (scientific journal)
CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs
Jun Wu, Marcela Vilarino, Keiichiro Suzuki, Daiji Okamura, Yanina Soledad Bogliotti, Insung Park, Joan Rowe, Bret McNabb, Pablo Juan Ross, Juan Carlos Izpisua Belmonte
SCIENTIFIC REPORTS Vol. 7 2017/09 Research paper (scientific journal)
Correction of a pathogenic gene mutation in human embryos
Hong Ma, Nuria Marti-Gutierrez, Sang-Wook Park, Jun Wu, Yeonmi Lee, Keiichiro Suzuki, Amy Koski, Dongmei Ji, Tomonari Hayama, Riffat Ahmed, Hayley Darby, Crystal Van Dyken, Ying Li, Eunju Kang, A. -Reum Park, Daesik Kim, Sang-Tae Kim, Jianhui Gong, Ying Gu, Xun Xu, David Battaglia, Sacha A. Krieg, David M. Lee, Diana H. Wu, Don P. Wolf, Stephen B. Heitner, Juan Carlos Izpisua Belmonte, Paula A. Mato, Jin-Soo Kim, Sanjiv Kaul, Shoukhrat Mitalipov
NATURE Vol. 548 No. 7668 p. 413-+ 2017/08 Research paper (scientific journal)
CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs
Lixia Wang, Fei Yi, Lina Fu, Jiping Yang, Si Wang, Zhaoxia Wang, Keiichiro Suzuki, Liang Sun, Xiuling Xu, Yang Yu, Jie Qiao, Juan Carlos Izpisua Belmonte, Ze Yang, Yun Yuan, Jing Qu, Guang-Hui Liu
PROTEIN & CELL Vol. 8 No. 5 p. 365-378 2017/05 Research paper (scientific journal)
Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells
Yuta Takahashi, Jun Wu, Keiichiro Suzuki, Paloma Martinez-Redondo, Mo Li, Hsin-Kai Liao, Min-Zu Wu, Reyna Hernandez-Benitez, Tomoaki Hishida, Maxim Nikolaievich Shokhirev, Concepcion Rodriguez Esteban, Ignacio Sancho-Martinez, Juan Carlos Izpisua Belmonte
SCIENCE Vol. 356 No. 6337 p. 503-+ 2017/05 Research paper (scientific journal)
Visualization of aging-associated chromatin alterations with an engineered TALE system
Ruotong Ren, Liping Deng, Yanhong Xue, Keiichiro Suzuki, Weiqi Zhang, Yang Yu, Jun Wu, Liang Sun, Xiaojun Gong, Huiqin Luan, Fan Yang, Zhenyu Ju, Xiaoqing Ren, Si Wang, Hong Tang, Lingling Geng, Weizhou Zhang, Jian Li, Jie Qiao, Tao Xu, Jing Qu, Guang-Hui Liu
CELL RESEARCH Vol. 27 No. 4 p. 483-504 2017/04 Research paper (scientific journal)
Interspecies Chimerism with Mammalian Pluripotent Stem Cells
Jun Wu, Aida Platero-Luengo, Masahiro Sakurai, Atsushi Sugawara, Maria Antonia Gil, Takayoshi Yamauchi, Keiichiro Suzuki, Yanina Soledad Bogliotti, Cristina Cuello, Mariana Morales Valencia, Daiji Okumura, Jingping Luo, Marcela Vilarino, Inmaculada Parrilla, Delia Alba Soto, Cristina A. Martinez, Tomoaki Hishida, Sonia Sanchez-Bautista, M. Llanos Martinez-Martinez, Huili Wang, Alicia Nohalez, Emi Aizawa, Paloma Martinez-Redondo, Alejandro Ocampo, Pradeep Reddy, Jordi Roca, Elizabeth A. Maga, Concepcion Rodriguez Esteban, W. Travis Berggren, Estrella Nunez Delicado, Jeronimo Lajara, Isabel Guillen, Pedro Guillen, Josep M. Campistol, Emilio A. Martinez, Pablo Juan Ross, Juan Carlos Izpisua Belmonte
CELL Vol. 168 No. 3 p. 473-+ 2017/01 Research paper (scientific journal)
Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders
Feron, F, Gepner, B, Lacassagne, E, Stephan, D, Mesnage, B, Blanchard, MP, Boulanger, N, Tardif, Carole, Deveze, A, Rousseau, Sylvain, others
Molecular psychiatry Vol. 21 No. 9 p. 1215-1215 2016 Research paper (scientific journal)
Publisher: Nature Publishing GroupiPSC Disease Modeling of Laminopathies
Liu, Guang-Hui, Yang, Jiping, Ding, Zhichao, Ocampo, Alej, ro, Qu, Jing, Suzuki, Keiichiro, Belmonte, Juan Carlos Izpisua
Human iPS Cells in Disease Modelling p. 53-67 2016
Publisher: Springer, TokyoPTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype
Shunlei Duan, Guohong Yuan, Xiaomeng Liu, Ruotong Ren, Jingyi Li, Weizhou Zhang, Jun Wu, Xiuling Xu, Lina Fu, Ying Li, Jiping Yang, Weiqi Zhang, Ruijun Bai, Fei Yi, Keiichiro Suzuki, Hua Gao, Concepcion Rodriguez Esteban, Chuanbao Zhang, Juan Carlos Izpisua Belmonte, Zhiguo Chen, Xiaomin Wang, Tao Jiang, Jing Qu, Fuchou Tang, Guang-Hui Liu
NATURE COMMUNICATIONS Vol. 6 2015/12 Research paper (scientific journal)
An alternative pluripotent state confers interspecies chimaeric competency
Daiji Okamura, Jun Wu, Mo Li, Keiichiro Suzuki, Juan Carlos Belmonte
GENES & GENETIC SYSTEMS Vol. 90 No. 6 p. 405-405 2015/12
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging
Weiqi Zhang, Jingyi Li, Keiichiro Suzuki, Jing Qu, Ping Wang, Junzhi Zhou, Xiaomeng Liu, Ruotong Ren, Xiuling Xu, Alejandro Ocampo, Tingting Yuan, Jiping Yang, Ying Li, Liang Shi, Dee Guan, Huize Pan, Shunlei Duan, Zhichao Ding, Mo Li, Fei Yi, Ruijun Bai, Yayu Wang, Chang Chen, Fuquan Yang, Xiaoyu Li, Zimei Wang, Emi Aizawa, April Goebl, Rupa Devi Soligalla, Pradeep Reddy, Concepcion Rodriguez Esteban, Fuchou Tang, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
SCIENCE Vol. 348 No. 6239 p. 1160-1168 2015/06 Research paper (scientific journal)
An alternative pluripotent state confers interspecies chimaeric competency
Jun Wu, Daiji Okamura, Mo Li, Keiichiro Suzuki, Chongyuan Luo, Li Ma, Yupeng He, Zhongwei Li, Chris Benner, Isao Tamura, Marie N. Krause, Joseph R. Nery, Tingting Du, Zhuzhu Zhang, Tomoaki Hishida, Yuta Takahashi, Emi Aizawa, Na Young Kim, Jeronimo Lajara, Pedro Guillen, Josep M. Campistol, Concepcion Rodriguez Esteban, Pablo J. Ross, Alan Saghatelian, Bing Ren, Joseph R. Ecker, Juan Carlos Izpisua Belmonte
NATURE Vol. 521 No. 7552 p. 316-+ 2015/05 Research paper (scientific journal)
Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing
Pradeep Reddy, Alejandro Ocampo, Keiichiro Suzuki, Jinping Luo, Sandra R. Bacman, Sion L. Williams, Atsushi Sugawara, Daiji Okamura, Yuji Tsunekawa, Jun Wu, David Lam, Xiong Xiong, Nuria Montserrat, Concepcion Rodriguez Esteban, Guang-Hui Liu, Ignacio Sancho-Martinez, Dolors Manau, Salva Civico, Francesc Cardellach, Maria del Mar O'Callaghan, Jaime Campistol, Huimin Zhao, Josep M. Campistol, Carlos T. Moraes, Juan Carlos Izpisua Belmonte
CELL Vol. 161 No. 3 p. 459-469 2015/04 Research paper (scientific journal)
CRISPR/Cas9 and TALE: beyond cut and paste
Liping Deng, Ruotong Ren, Jun Wu, Keiichiro Suzuki, Juan Carlos Izpisua Belmote, Guang-Hui Liu
PROTEIN & CELL Vol. 6 No. 3 p. 157-159 2015/03 Research paper (scientific journal)
Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells
Hsin-Kai Liao, Ying Gu, Arturo Diaz, John Marlett, Yuta Takahashi, Mo Li, Keiichiro Suzuki, Ruo Xu, Tomoaki Hishida, Chan-Jung Chang, Concepcion Rodriguez Esteban, John Young, Juan Carlos Izpisua Belmonte
NATURE COMMUNICATIONS Vol. 6 2015/03 Research paper (scientific journal)
Recombination and gene targeting in Neurospora
Suzuki, Keiichiro, Inoue, Hirokazu
Genetic Transformation Systems in Fungi, Volume 1 p. 255-262 2015
Publisher: Springer, ChamModelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs
Guang-Hui Liu, Keiichiro Suzuki, Mo Li, Jing Qu, Nuria Montserrat, Carolina Tarantino, Ying Gu, Fei Yi, Xiuling Xu, Weiqi Zhang, Sergio Ruiz, Nongluk Plongthongkum, Kun Zhang, Shigeo Masuda, Emmanuel Nivet, Yuji Tsunekawa, Rupa Devi Soligalla, April Goebl, Emi Aizawa, Na Young Kim, Jessica Kim, Ilir Dubova, Ying Li, Ruotong Ren, Chris Benner, Antonio del Sol, Juan Bueren, Juan Pablo Trujillo, Jordi Surralles, Enrico Cappelli, Carlo Dufour, Concepcion Rodriguez Esteban, Juan Carlos Izpisua Belmonte
NATURE COMMUNICATIONS Vol. 5 2014/07 Research paper (scientific journal)
The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa
Tetsu Yoshida, Yoko Ozawa, Keiichiro Suzuki, Kenya Yuki, Manabu Ohyama, Wado Akamatsu, Yumi Matsuzaki, Shigeto Shimmura, Kohnosuke Mitani, Kazuo Tsubota, Hideyuki Okano
MOLECULAR BRAIN Vol. 7 2014/06 Research paper (scientific journal)
A Cut above the Rest: Targeted Genome Editing Technologies in Human Pluripotent Stem Cells*
Mo Li, Keiichiro Suzuki, Na Young Kim, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 289 No. 8 p. 4594-4599 2014/02 Research paper (scientific journal)
Direct reprogramming of porcine fibroblasts to neural progenitor cells
Xiu-Ling Xu, Ji-Ping Yang, Li-Na Fu, Ruo-Tong Ren, Fei Yi, Keiichiro Suzuki, Kai Liu, Zhi-Chao Ding, Jing Qu, Wei-Qi Zhang, Ying Li, Ting-Ting Yuan, Guo-Hong Yuan, Li-Na Sui, Di Guan, Shun-Lei Duan, Hui-Ze Pan, Ping Wang, Xi-Ping Zhu, Nuria Montserrat, Ming Li, Rui-Jun Bai, Lin Liu, Juan Carlos Izpisua Belmonte, Guang-Hui Liu
PROTEIN & CELL Vol. 5 No. 1 p. 4-7 2014/01 Research paper (scientific journal)
Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes
Ying Gu, Guang-Hui Liu, Nongluk Plongthongkum, Christopher Benner, Fei Yi, Jing Qu, Keiichiro Suzuki, Jiping Yang, Weiqi Zhang, Mo Li, Nuria Montserrat, Isaac Crespo, Antonio del Sol, Concepcion Rodriguez Esteban, Kun Zhang, Juan Carlos Izpisua Belmonte
PROTEIN & CELL Vol. 5 No. 1 p. 59-68 2014/01 Research paper (scientific journal)
Concealing cellular defects in pluripotent stem cells
Weiqi Zhang, Jing Qu, Keiichiro Suzuki, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
TRENDS IN CELL BIOLOGY Vol. 23 No. 12 p. 587-592 2013/12 Research paper (scientific journal)
Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells
Yun Xia, Emmanuel Nivet, Ignacio Sancho-Martinez, Thomas Gallegos, Keiichiro Suzuki, Daiji Okamura, Min-Zu Wu, Ilir Dubova, Concepcion Rodriguez Esteban, Nuria Montserrat, Josep M. Campistol, Juan Carlos Izpisua Belmonte
NATURE CELL BIOLOGY Vol. 15 No. 12 p. 1507-+ 2013/12 Research paper (scientific journal)
Oncofetal Gene SALL4 in Aggressive Hepatocellular Carcinoma
Shigeo Masuda, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte
NEW ENGLAND JOURNAL OF MEDICINE Vol. 369 No. 12 p. 1171-1171 2013/09 Research paper (scientific journal)
Albumin gene targeting in human embryonic stem cells and induced pluripotent stem cells with helper-dependent adenoviral vector to monitor hepatic differentiation
Kahoko Umeda, Keiichiro Suzuki, Taiji Yamazoe, Nobuaki Shiraki, Yuichiro Higuchi, Kumiko Tokieda, Kazuhiko Kume, Kohnosuke Mitani, Shoen Kume
Stem Cell Research Vol. 10 No. 2 p. 179-194 2013/03 Research paper (scientific journal)
Establishment of hepatic and neural differentiation platforms of Wilson's disease specific induced pluripotent stem cells
Fei Yi, Jing Qu, Mo Li, Keiichiro Suzuki, Na Young Kim, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
PROTEIN & CELL Vol. 3 No. 11 p. 855-863 2012/11 Research paper (scientific journal)
Induced neural stem cells: a new tool for studying neural development and neurological disorders
Guang-Hui Liu, Fei Yi, Keiichiro Suzuki, Jing Qu, Juan Carlos Izpisua Belmonte
CELL RESEARCH Vol. 22 No. 7 p. 1087-1091 2012/07 Research paper (scientific journal)
Reprogramming based gene therapy for inherited red blood cell disorders
Xiuling Xu, Jing Qu, Keiichiro Suzuki, Mo Li, Weizhou Zhang, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
CELL RESEARCH Vol. 22 No. 6 p. 941-944 2012/06 Research paper (scientific journal)
Cardiosphere-derived cells for heart regeneration
Shigeo Masuda, Nuria Monserrat, Daiji Okamura, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte
LANCET Vol. 379 No. 9835 p. 2425-2426 2012/06 Research paper (scientific journal)
Novel Human Adenovirus Strain, Bangladesh
Yuki Matsushima, Hideaki Shimizu, Atsuko Kano, Etsuko Nakajima, Yoko Ishimaru, Shuvra Kanti Dey, Yuki Watanabe, Fuyuka Adachi, Keiichiro Suzuki, Kohnosuke Mitani, Tsuguto Fujimoto, Tung Gia Phan, Hiroshi Ushijima
EMERGING INFECTIOUS DISEASES Vol. 18 No. 5 p. 846-848 2012/05 Research paper (scientific journal)
Efficient and Accurate Homologous Recombination in hESCs and hiPSCs Using Helper-dependent Adenoviral Vectors
Emi Aizawa, Yuka Hirabayashi, Yuzuru Iwanaga, Keiichiro Suzuki, Kenji Sakurai, Miho Shimoji, Kazuhiro Aiba, Tamaki Wada, Norie Tooi, Eihachiro Kawase, Hirofumi Suemori, Norio Nakatsuji, Kohnosuke Mitani
MOLECULAR THERAPY Vol. 20 No. 2 p. 424-431 2012/02 Research paper (scientific journal)
Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs
Mo Li, Keiichiro Suzuki, Jing Qu, Preeti Saini, Ilir Dubova, Fei Yi, Jungmin Lee, Ignacio Sancho-Martinez, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
CELL RESEARCH Vol. 21 No. 12 p. 1740-1744 2011/12 Research paper (scientific journal)
Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs
Guang-Hui Liu, Keiichiro Suzuki, Jing Qu, Ignacio Sancho-Martinez, Fei Yi, Mo Li, Sachin Kumar, Emmanuel Nivet, Jessica Kim, Rupa Devi Soligalla, Ilir Dubova, April Goebl, Nongluk Plongthongkum, Ho-Lim Fung, Kun Zhang, Jeanne F. Loring, Louise C. Laurent, Juan Carlos Izpisua Belmonte
CELL STEM CELL Vol. 8 No. 6 p. 688-694 2011/06 Research paper (scientific journal)
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
Guang-Hui Liu, Basam Z. Barkho, Sergio Ruiz, Dinh Diep, Jing Qu, Sheng-Lian Yang, Athanasia D. Panopoulos, Keiichiro Suzuki, Leo Kurian, Christopher Walsh, James Thompson, Stephanie Boue, Ho Lim Fung, Ignacio Sancho-Martinez, Kun Zhang, John Yates, Juan Carlos Izpisua Belmonte
NATURE Vol. 472 No. 7342 p. 221-225 2011/04 Research paper (scientific journal)
Homologous Recombination in human pluripotent stem \ncells using helper-dependent adenovirua vectors,
Suzuki K, Hirabayashi Y, Aizawa E, Iwanaga Y, Tokumitsu A, Sakurai K, Shimoji M, Aiba K, Wada T, Tooi N, Kawase E, Suemori H, Nakatsuji N, Mitani K
9th International Society for Stem Cell Research（Toronto, 2011, 6, 17）. 2011
DEVELOPMENT OF ZINC-FINGER NUCLEASES TARGETING THE HUMAN HPRT LOCUS
Keiichiro Suzuki, Akihiro Kishimoto, Kaoru Mitsui, Kohnosuke Mitani
JOURNAL OF GENE MEDICINE Vol. 12 No. 12 p. 1063-1063 2010/12
Integration of exogenous DNA into mouse embryonic stem cell chromosomes shows preference into genes and frequent modification at junctions
Keiichiro Suzuki, Fumi Ohbayashi, Itoshi Nikaido, Akihiko Okuda, Haruyoshi Takaki, Yasushi Okazaki, Kohnosuke Mitani
CHROMOSOME RESEARCH Vol. 18 No. 2 p. 191-201 2010/02 Research paper (scientific journal)
OPTIMAZATION OF ENVELOPE AND PROMOTER FOR LINTIVIRAL GENE TRANSFER INTO HUMAN EMBRYONIC STEM CELLS
Emi Aizawa, Kaoru Mitsui, Keiichiro Suzuki, Hirofumi Suemori, Norio Nakatsuji, Ko Mitani
JOURNAL OF GENE MEDICINE Vol. 11 No. 12 p. 1184-1184 2009/12
HOMOLOGOUS RECOMBINATION IN CYNOMOLGUS MONKEY EMBRYONIC STEM CELLS WITH AN INTEGRASE-DEFECTIVE LENTIVIRAL VECTOR
Emi Aizawa, Kaoru Mitsui, Keiichiro Suzuki, Hirofumi Suemori, Norio Nakatsuji, Ko Mitani
JOURNAL OF GENE MEDICINE Vol. 11 No. 12 p. 1184-1184 2009/12
HIGHLY EFFICIENT GENE TRANSFER AND GENETIC MANIPULATION IN HUMAN EMBRYONIC STEM CELLS USING VIRAL VECTORS
Ko Mitani, Keiichiro Suzuki, Emi Aizawa, Kaoru Mitsui, Shiiba Haruka, Kouichi Hasegawa, Esihachiro Kawase, Hirofumi Suemori, Norio Nakatsuji
JOURNAL OF GENE MEDICINE Vol. 11 No. 12 p. 1185-1185 2009/12
Gene targeting in human pluripotent stem cells with adeno-associated virus vectors
Kaoru Mitsui, Keiichiro Suzuki, Emi Aizawa, Eihachiro Kawase, Hirofumi Suemori, Norio Nakatsuji, Kohnosuke Mitani
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 388 No. 4 p. 711-717 2009/10 Research paper (scientific journal)
Highly Efficient Transient Gene Expression and Gene Targeting in Human Pluripotent Stem Cells with Helper-Dependent Adenoviral Vectors
Keiichiro Suzuki, Kaoru Mitsui, Emi Aizawa, Kouichi Hasegawa, Eihachiro Kawase, Hirofumi Suemori, Norio Nakatsuji, Ko Mitani
MOLECULAR THERAPY Vol. 17 p. S132-S132 2009/05
Optimization of Vector Design for Lentiviral Gene Transfer into Human Embryonic Stem Cells
Emi Aizawa, Kaoru Mitsui, Keiichiro Suzuki, Hirofumi Suemori, Norio Nakatsuji, Ko Mitani
MOLECULAR THERAPY Vol. 17 p. S265-S265 2009/05
Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors
Keiichiro Suzuki, Kaoru Mitsui, Emi Aizawa, Kouichi Hasegawa, Eihachiro Kawase, Toshiyuki Yamagishi, Yoshihiko Shimizu, Hirofumi Suemori, Norio Nakatsuji, Kohnosuke Mitani
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 105 No. 37 p. 13781-13786 2008/09 Research paper (scientific journal)
Gene expression and homologous recombination in cynomolgus monkey ES cells with helper-dependent adenoviral vectors
Ko Mitani, Keiichiro Suzuki, Kouichi Hasegawa, Kaoru Mitsui, Emi Aizawa, Haruka Shiiba, Hirofumi Suemori, Norio Nakatsuji
JOURNAL OF GENE MEDICINE Vol. 10 No. 4 p. 465-465 2008/04
A role of POL32 homologue in translesion DNA synthesis in Neurospora crassa
Masahiro Urio, Keiichiro Suzuki, Tsuyoshi Kawabata, Hirokazu Inoue
GENES & GENETIC SYSTEMS Vol. 82 No. 6 p. 557-557 2007/12
Neurosprora crassa RAD5 homologue, mus-41, inactivation results in higher sensitivity to mutagens but has little effect on PCNA-ubiquitylation in response to UV-irradiation
Tsuyoshi Kawabata, Akihiro Kato, Keiichiro Suzuki, Hirokazu Inoue
CURRENT GENETICS Vol. 52 No. 3-4 p. 125-135 2007/09 Research paper (scientific journal)
Analysis of gene targeting mechanism in Neurospora crassa
Chihiro Takakura, Yoshinori Ando, Kazuma Ishibashi, Keiichiro Suzuki, Hirokazu Inoue
GENES & GENETIC SYSTEMS Vol. 81 No. 6 p. 411-411 2006/12
Nonhomologous chromosomal integration of foreign DNA is completely dependent on MUS-53 (human Lig4 homolog) in Neurospora
Kazuma Ishibashi, Keiichiro Suzuki, Yoshinori Ando, Chihiro Takakura, Hirokazu Inoue
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 103 No. 40 p. 14871-14876 2006/10 Research paper (scientific journal)
Regulated expression and dynamic changes in subnuclear localization of mammalian Rad18 under normal and genotoxic conditions
S Masuyama, S Tateishi, K Yomogida, Y Nishimune, K Suzuki, Y Sakuraba, H Inoue, M Ogawa, M Yamaizumi
GENES TO CELLS Vol. 10 No. 8 p. 753-762 2005/08 Research paper (scientific journal)
Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination
S Miyase, S Tateishi, K Watanabe, K Tomita, K Suzuki, H Inoue, M Yamaizumi
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 280 No. 1 p. 515-524 2005/01 Research paper (scientific journal)
Srs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa
K Suzuki, A Kato, Y Sakuraba, H Inoue
NUCLEIC ACIDS RESEARCH Vol. 33 No. 6 p. 1848-1858 2005 Research paper (scientific journal)
Highly efficient gene replacements in Neurospora strains deficient for nonhomologous end-joining
Y Ninomiya, K Suzuki, C Ishii, H Inoue
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 101 No. 33 p. 12248-12253 2004/08 Research paper (scientific journal)
Lessons from the genome sequence of Neurospora crassa: Tracing the path from genomic blueprint to multicellular organism
KA Borkovich, LA Alex, O Yarden, M Freitag, GE Turner, ND Read, S Seiler, D Bell-Pedersen, J Paietta, N Plesofsky, M Plamann, M Goodrich-Tanrikulu, U Schulte, G Mannhaupt, FE Nargang, A Radford, C Selitrennikoff, JE Galagan, JC Dunlap, JJ Loros, D Catcheside, H Inoue, R Aramayo, M Polymenis, EU Selker, MS Sachs, GA Marzluf, Paulsen, I, R Davis, DJ Ebbole, A Zelter, ER Kalkman, R O&apos, Rourke, F Bowring, J Yeadon, C Ishii, K Suzuki, W Sakai, R Pratt
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS Vol. 68 No. 1 p. 1-+ 2004/03 Research paper (scientific journal)
Development of the new approach for gene therapy by using peptides related to intercellular communication
山本翔吾, 廣瀬淳, 岩井成憲, 鈴木啓一郎, 鈴木啓一郎, 鈴木啓一郎
日本分子生物学会年会プログラム・要旨集(Web) Vol. 46th 2023 Research paper, summary (national, other academic conference)
CRISPRシステムを用いた遺伝子変異検出系の開発
國政啓, 西野和美, 鈴木啓一郎, 鈴木啓一郎
日本肺癌学会学術集会号 Vol. 64th (CD-ROM) 2023
Development of CRISPR-Cas inspired protein using click chemistry and its application to imaging
中村惇, 白石都, 山元淳平, 鈴木啓一郎, 鈴木啓一郎, 鈴木啓一郎
日本分子生物学会年会プログラム・要旨集(Web) Vol. 46th 2023 Research paper, summary (national, other academic conference)
Gene modification in somatic cells using genome-editing technology
鈴木啓一郎, 鈴木啓一郎, 鈴木啓一郎
日本生物学的精神医学会誌(Web) Vol. 34 No. 4 2023 Research paper, summary (national, other academic conference)
表皮組織に最適化された新規AAVカプシドの開発
SHEN Qi, SHEN Qi, DU ZeNing, 森脇裕太, 栗田昌和, 岡崎睦, 鈴木啓一郎
日本形成外科学会基礎学術集会プログラム・抄録集 Vol. 31st 2022
Development of novel gene therapy via in vivo genome-editing technology
鈴木啓一郎
日本再生医療学会総会(Web) Vol. 21st 2022
高効率な局所的遺伝子送達を可能とするDNA担持ナノファイバーの開発
古野琴子, 中畑雅樹, 小嶋勝, 鈴木啓一郎, 境慎司
化学工学会年会研究発表講演要旨集(CD-ROM) Vol. 86th 2021
分裂・非分裂細胞に有効なゲノム編集技術の開発と生体への応用
鈴木啓一郎
日本生化学会大会(Web) Vol. 94th 2021
ゲノム編集技術による疾患モデリングおよび生体内治療法の開発
鈴木 啓一郎
次世代薬理学セミナー要旨集 Vol. 2021.1 2021
Publisher: 公益社団法人 日本薬理学会
遺伝子治療に向けた生体内ゲノム編集
Vol. 10 No. 4 p. 52-59 2020/10
Publisher: メディカルドゥ
生体内ゲノム編集治療技術の開発
スズキ ケイイチロウ
月刊Precision Medicine Vol. 3 No. 6 p. 524-527 2020/06
Publisher: 北隆館
ゲノム編集技術のオフターゲット解析法
スズキ ケイイチロウ
医学のあゆみ Vol. 273 No. 9 p. 909-915 2020/05/30
Publisher: 医歯薬出版
Development of Novel Genome-editing Method Using a Customized Damaged-DNA Template
鈴木啓一郎
豊田研究報告 No. 73 2020 Internal/External technical report, pre-print, etc.
生体内での遺伝子導入を可能とするplasmid担持ナノファイバーの開発
古野琴子, 鈴木啓一郎, 境慎司
化学工学会年会研究発表講演要旨集(CD-ROM) Vol. 85th 2020
優性変異を持つ遺伝性疾患に対する根本的治療法の開発
鈴木 啓一郎
上原記念生命科学財団研究報告集 Vol. 34 p. 1-5 2020 Internal/External technical report, pre-print, etc.
Publisher: 上原記念生命科学財団
HITI法と神経細胞での遺伝子改変
スズキ ケイイチロウ
Vol. 51 No. 3 p. 119-122 2019/03
Publisher: ニューサイエンス社
HITI法を用いた生体内ゲノム編集技術の開発と治療応用
鈴木啓一郎, 鈴木啓一郎
日本神経学会学術大会プログラム・抄録集 Vol. 60th 2019
CRISPR関連遺伝子Csn2を利用した哺乳動物細胞における正確な相同組換え修復法の開発
立花大輔, 相澤絵美, 岩井成憲, 鈴木啓一郎, 鈴木啓一郎
日本分子生物学会年会プログラム・要旨集(Web) Vol. 42nd 2019 Research paper, summary (national, other academic conference)
生体内ゲノム編集技術HITI法の開発と治療応用
鈴木啓一郎, 鈴木啓一郎
日本形成外科学会基礎学術集会プログラム・抄録集 Vol. 28th 2019
生体内ゲノム編集技術の開発とゲノム編集治療技術の確立
鈴木啓一郎
化学工学会秋季大会研究発表講演要旨集(CD-ROM) Vol. 50th 2018
生体内ゲノム編集技術HITI法を用いた遺伝病動物モデルのゲノム編集治療
鈴木啓一郎, 鈴木啓一郎, 恒川雄二, 山本真子, REYNA Hernandez-Benitez, JUN Wu, CARLOS Izpisua Belmonte Juan
日本再生医療学会総会(Web) Vol. 17th 2018 Research paper, summary (national, other academic conference)
生体内ゲノム編集技術を用いた難治性遺伝病に対するテーラーメイド医療技術の開発
鈴木啓一郎
倉田奨励金研究報告書(Web) Vol. 48 2017 Internal/External technical report, pre-print, etc.
ゲノム編集のupdate
鈴木啓一郎
感染・炎症・免疫 Vol. 47 No. 3 2017 Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
非相同組み込み機構を利用した生体内ゲノム編集技術の開発
鈴木啓一郎
日本分子生物学会年会プログラム・要旨集(Web) Vol. 39th 2016 Research paper, summary (national, other academic conference)
ゲノム編集ツールの開発動向と関連技術 最新CRISPR関連アプリケーション 9.オフターゲット解析法
鈴木啓一郎
実験医学 Vol. 34 No. 20 2016 Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
新規多能性がもたらす異種間キメラ形成能
岡村大治, 岡村大治, WU Jun, LI Mo, 鈴木啓一郎, LUO Chongyuan, LUO Chongyuan, MA Li, HE Yupeng, LI Zhongwei, BENNER Chris, 田村功, KRAUSE Marie N., NERY Joseph R., DU Tingting, ZHANG Zhuzhu, 菱田友昭, 高橋悠太, 高橋悠太, 相澤絵美, KIM Na Young, LAJARA Jeronimo, GUILLEN Pedro, GUILLEN Pedro, CAMPISTOL Joseph M., ESTEBAN Concepcion Rodriguez, ROSS Pablo J., SAGHATELIAN Alan, REN Bing, ECKER Joseph R., ECKER Joseph R., BELMONTE Juan Carlos I.
日本生化学会大会(Web) Vol. 88th 2015
新規多能性がもたらす異種間キメラ形成能
岡村大治, ウー ジュン, リー モー, 鈴木啓一郎, ベルモンテ フアンカルロス
日本遺伝学会大会プログラム・予稿集 Vol. 87th 2015
ゲノム編集技術により遺伝子修復された遺伝病iPS細胞の全ゲノム配列解析
鈴木啓一郎, YU Chang, QU Jing, LI Mo, YAO Xiaotian, YUAN Tingting, GOEBL April, TANG Senwei, REN Ruotong, AIZAWA Emi, ZHANG Fan, XU Xiuling, SOLIGALLA Rupa Devi, CHEN Feng, KIM Jessica, KIM Na Young, LIAO Hsin-Kai, BENNER Chris, RODRIGUEZ Esteban Concepcion, YABIN Jin, LIU Guang-Hui, LI Yingrui, BELMONTE Juan Carlos Izpisua
日本分子生物学会年会プログラム・要旨集(Web) Vol. 37th 2014 Research paper, summary (national, other academic conference)
iPS細胞を用いた網膜色素変性症における視細胞の変性機構の解析
吉田哲, 小沢洋子, 鈴木啓一郎, 平林由香, 鈴木禎史, 小泉春菜, 結城賢弥, 小林哲郎, 大山学, 天谷雅行, 岡田洋平, 赤松和土, 松崎有未, 三谷幸之介, 榛村重人, 坪田一男, 岡野栄之
再生医療 Vol. 12 2013
Albumin/mKo1ノックイン ヒトES,iPS細胞株の樹立とその解析
梅田香穂子, 鈴木啓一郎, 山添太士, 白木伸明, 粂和彦, 三谷幸之助, 粂昭苑
日本分子生物学会年会プログラム・要旨集(Web) Vol. 35th 2012
ヘルパー依存型アデノウイルスを用いたヒトiPS細胞の遺伝子変異治療
吉田哲, 小泉春菜, 結城賢弥, 平林由香, 鈴木啓一郎, 三谷幸之介, 小林哲郎, 大山学, 天谷雅行, 岡田洋平, 赤松和土, 坪田一男, 榛村重人, 小沢洋子, 岡野栄之
再生医療 Vol. 10 2011
ヒト多能性幹細胞におけるウイルスベクターを用いた遺伝子ターゲッティング
三谷幸之介, 鈴木啓一郎, 三井薫, 相澤絵美
再生医療 Vol. 9 2010
哺乳類細胞における外来DNAの染色体組込み部位の解析:不正確な非相同末端結合による発現遺伝子領域内への組込み
鈴木啓一郎, 大林富美, 二階堂愛, 奥田晶彦, 高木晴良, 岡崎康司, 三谷幸之介
生化学 2010 Research paper, summary (national, other academic conference)
アデノ随伴ウイルスベクターを用いたヒト多能性幹細胞への遺伝子ターゲッティング
Mitsui K, Suzuki K, Aizawa E, Kawase E, Suemori H, Nakatsuji N, Mitani K
Vol. 388 No. 4 p. 711-717 2009/10
クローズアップ実験法 Series192 ヘルパー依存型アデノウイルスベクターの作製法
鈴木啓一郎, 三谷幸之介
実験医学 Vol. 27 No. 11 2009 Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
Genetic Engineering【遺伝子工学】01 改良型アデノウイルスベクターを利用した効率のよい「ヒトES細胞の遺伝子操作」の実現
鈴木啓一郎, 三谷幸之介
メディカルバイオ Vol. 5 No. 6 2008 Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
アカパンカビにおけるPOL32ホモログの損傷乗り越え合成での役割
瓜尾政博, 鈴木啓一郎, 川端剛, 井上弘一
日本遺伝学会大会プログラム・予稿集 Vol. 79th 2007 Research paper, summary (national, other academic conference)
アカパンカビにおける遺伝子ターゲティング機構の解析
高倉千裕, 安藤良徳, 石橋和真, 鈴木啓一郎, 井上弘一
生化学 2007 Research paper, summary (national, other academic conference)
アデノ随伴ウイルス(AAV)ベクターを用いたヒトES細胞の相同組換
三井薫, 鈴木啓一郎, PAIBOONSUKWONG Kittiphong, 相澤絵美, 川瀬栄八郎, 末盛博文, 中辻憲夫, 三谷幸之介
生化学 2007
アカパンカビにおける効率的遺伝子ターゲット法の確立 KU遺伝子の破壊により遺伝子ターゲット効率が100%に
井上弘一, 鈴木啓一郎
化学と生物 Vol. 43 No. 12 p. 768-770 2005 Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
Publisher: 日本農芸化学会
アカパンカビにおけるRAD51パラログ遺伝子の解析
村山泰斗, 鈴木啓一郎, 井上弘一
日本分子生物学会年会プログラム・講演要旨集 Vol. 27th 2004 Research paper, summary (national, other academic conference)
アカパンカビにおける出芽酵母RAD18ホモログuvs-2遺伝子の分子生物学的解析
鈴木啓一郎, 桜庭喜行, 井上弘一
日本分子生物学会年会プログラム・講演要旨集 Vol. 26th 2003 Research paper, summary (national, other academic conference)
アカパンカビの複製後修復におけるncUBC13,ncMMS2の役割
川端剛, 鈴木啓一郎, 井上弘一
日本分子生物学会年会プログラム・講演要旨集 Vol. 26th 2003 Research paper, summary (national, other academic conference)
DNA損傷により停止した複製フォークを再開するメカニズムの解析
鈴木 啓一郎
鈴木啓一郎 2005
生体内ゲノム編集技術を用いた遺伝性および非遺伝性疾患モデルの治療
鈴木 啓一郎
第67回日本腎臓学会学術総会 2024/06/28
Genome editing therapy through in vivo gene knock-in methods: the future of treating inherited diseases
Keiichiro Suzuki
On-line seminar at Hanyang University 2024/02/16
生体内遺伝子ノックイン技術を用いた新規遺伝子治療法の開発
鈴木 啓一郎
第29回日本遺伝子細胞治療学会学術集会 2023/09/13
ゲノム編集技術を用いた体細胞遺伝子操作
鈴木 啓一郎
BPCNPNPPP4学会合同年会 2022/11/05
Development of in vivo genome editing technology in somatic cells
Keiichiro Suzuki
2022/03/16
分裂細胞または非分裂細胞のゲノム編集のための方法と組成物
恒川 雄二, イズピスア ベルモンテ,ファン カルロス, 鈴木 啓一郎, ヘルナンデス-ベニテス,レイナ, ウー,ジュン
特許第7493563号
出願日:2017/07/14
登録日:2024/05/23
in vivo遺伝子編集のための組成物および方法
イズピスア ベルモンテ, ジュアン カルロス, 鈴木 啓一郎, 辻 真子, ヘルナンデス-ベニテス, レイナ
特表2022-553607
出願日:2019/09/20
非分裂細胞のゲノム編集のための方法と組成物
恒川 雄二, イズピスア ベルモンテ,ファン カルロス, 鈴木 啓一郎, ヘルナンデス-ベニテス,レイナ, ウー,ジュン
特表2019-524098
出願日:2017/07/14
非分裂細胞のゲノム編集のための方法と組成物
恒川 雄二, イズピスア ベルモンテ,ファン カルロス, 鈴木 啓一郎, ヘルナンデス-ベニテス,レイナ, ウー,ジュン
特表2019-524098
出願日:2017/07/14
非分裂細胞のゲノム編集のための方法と組成物
恒川 雄二, イズピスア ベルモンテ,ファン カルロス, 鈴木 啓一郎, ヘルナンデス-ベニテス,レイナ, ウー,ジュン
出願日:2024/05/20
非分裂細胞のゲノム編集のための方法と組成物
恒川 雄二, イズピスア ベルモンテ,ファン カルロス, 鈴木 啓一郎, ヘルナンデス-ベニテス,レイナ, ウー,ジュン
出願日:2022/10/03
遺伝子ターゲティングに伴うランダムインテグレーションを抑える方法
井上 弘一, 鈴木 啓一郎, 石橋 和真, 安藤 良徳, 高倉 千裕, 二宮 祐子
出願日:2006/05/11
Lipid Nanoparticles Enable Efficient In Vivo DNA Knock-In via HITI-Mediated Genome Editing
Hirose Jun, Aizawa Emi, Yamamoto Shogo, Xu Mingyao, Iwai Shigenori, Suzuki Keiichiro
Biomolecules Vol. 14 No. 12 2024/12/06
