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Ishii Masaru

石井 優

Graduate School of Frontier Biosciences Department of Frontier Biosciences, Professor

keyword pharmacology,in vivo imaging,immunology,osteobiology

Education

  • - 1998, Osaka University, Faculty of Medicine
  • - 1998, Osaka University, Faculty of Medicine, Medical School

Research History

  • 2013/04 - Present, Osaka University, Graduate School of Medicine
  • 2006 - Present, : National Institute of Allergy and Infectious Diseases, National Institutes of Health (Maryland/USA), Visiting Researcher,
  • 2005 - Present, : National Osaka-Minami Medical Center (Osaka/Japan), Principal Investigator,
  • 2011/04 - 2013/03, Osaka University, WPI Immunology Frontier Research Center
  • 2009/04 - 2011/03, Osaka University, WPI Immunology Frontier Research Center
  • 2005 - 2009, National Hospital Organization
  • 2006 - 2008, : - Human Frontier Science Program Research Fellow
  • 2006 - 2008, : - 米国国立衛生学研究所・国立アレルギー感染症研究所・客員研究員
  • 2000 - 2005, 大阪大学医学系研究科, 助手
  • 2000 - 2005, : Osaka University Medical School (Osaka/Japan), Assistant Professor,

Research Areas

  • Life sciences, Allergies and connective tissue disease
  • Life sciences, Internal medicine - General
  • Life sciences, Immunology
  • Life sciences, Medical biochemistry
  • Life sciences, Pharmacology
  • Life sciences, Clinical pharmacy
  • Life sciences, Physiology

Professional Memberships

  • Japanese College of Rheumatology
  • Japanese Society of Physiology
  • Japanese Society of Pharmacology
  • Japanese Society of Allergology
  • Japanese Society of Internal Medicine
  • Japanese Society of Biochemistry
  • Biophysical Society
  • 日本リウマチ学会
  • Biophysical Society
  • 日本アレルギー学会
  • 日本内科学会
  • 日本生化学会
  • 日本薬理学会

Papers

  • In vivo dynamic analysis of BMP-2-induced ectopic bone formation, Kunihiko Hashimoto,Takashi Kaito,Masayuki Furuya,Shigeto Seno,Daisuke Okuzaki,Junichi Kikuta,Hiroyuki Tsukazaki,Hideo Matsuda,Hideki Yoshikawa,Masaru Ishii, Scientific Reports, Vol. 10, No. 1, 2020/12/01
  • An Acid Activatable Fluorescence Probe for Imaging Osteocytic Bone Resorption Activity in Deep Bone Cavities, Ryu Hashimoto,Masafumi Minoshima,Junichi Kikuta,Shinya Yari,Steven D. Bull,Masaru Ishii,Kazuya Kikuchi, Angewandte Chemie International Edition, Wiley, 2020/08/03
  • Nonlinear optics with near-infrared excitation enable real-time quantitative diagnosis of human cervical cancers, Takahiro Matsui,Ryo Tamoto,Akio Iwasa,Masafumi Mimura,Seiji Taniguchi,Tetsuo Hasegawa,Takao Sudo,Hiroki Mizuno,Junichi Kikuta,Ichiro Onoyama,Kaoru Okugawa,Mayu Shiomi,Shinya Matsuzaki,Eiichi Morii,Tadashi Kimura,Kiyoko Kato,Yasujiro Kiyota,Masaru Ishii, Cancer Research, American Association for Cancer Research (AACR), p. canres.0348.2020-canres.0348.2020, 2020/07/23
  • Local sympathetic neurons promote neutrophil egress from the bone marrow at the onset of acute inflammation, Tomoka Ao,Junichi Kikuta,Takao Sudo,Yutaka Uchida,Kenta Kobayashi,Masaru Ishii, International Immunology, Oxford University Press (OUP), 2020/04/23
  • Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway., Maho Morimatsu,Erika Yamashita,Shigeto Seno,Takao Sudo,Junichi Kikuta,Hiroki Mizuno,Daisuke Okuzaki,Daisuke Motooka,Masaru Ishii, Inflammation and regeneration, Vol. 40, p. 15-15, 2020
  • Application of Imaging Technology to Humans, Takahiro Matsui,Masaru Ishii, Make Life Visible, Springer Singapore, p. 213-218, 2020
  • Tracking and Analysis of FUCCI-Labeled Cells Based on Particle Filters and Time-to-Event Analysis, Kenji Fujimoto,Shigeto Seno,Hironori Shigeta,Tomohiro Mashita,Masaru Ishii,Hideo Matsuda, International Journal of Bioscience, Biochemistry and Bioinformatics, International Academy Publishing (IAP), Vol. 10, No. 2, p. 94-109, 2020
  • Thrombomodulin induces anti-inflammatory effects by inhibiting the rolling adhesion of leukocytes in vivo, Shino Nishizawa,Junichi Kikuta,Shigeto Seno,Masahiro Kajiki,Ryuichi Tsujita,Hiroki Mizuno,Takao Sudo,Tomoka Ao,Hideo Matsuda,Masaru Ishii, Journal of Pharmacological Sciences, 2020/01
  • IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95., Kim H,Takegahara N,Walsh MC,Middleton SA,Yu J,Shirakawa J,Ueda J,Fujihara Y,Ikawa M,Ishii M,Kim J,Choi Y, Bone Research, 2020
  • Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1., Hasegawa T,Kikuta J,Sudo T,Matsuura Y,Matsui T,Simmons S,Ebina K,Hirao M,Okuzaki D,Yoshida Y,Hirao A,Kalinichenko VV,Yamaoka K,Takeuchi T,Ishii M, Nature immunology, Vol. 20, No. 12, p. 1631-1643, 2019/12
  • Single-cell transcriptome analysis of mouse leukocytes in inflammatory stimulation, Naoki Osato,Hironori Shigeta,Shigeto Seno,Yutaka Uchida,Junichi Kikuta,Masaru Ishii,Hideo Matsuda, 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), IEEE, p. 1229-1231, 2019/11
  • High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node., Simmons S,Sasaki N,Umemoto E,Uchida Y,Fukuhara S,Kitazawa Y,Okudaira M,Inoue A,Tohya K,Aoi K,Aoki J,Mochizuki N,Matsuno K,Takeda K,Miyasaka M,Ishii M, eLife, Vol. 8, 2019/10
  • Analyzing Leukocyte Migration Trajectories by Deformable Image Matching, Hironori Shigeta,Shigeto Seno,Shino Nishizawa,Yutaka Uchida,Junichi Kikuta,Masaru Ishii,Hideo Matsuda, IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE), p. 94-98, 2019/10
  • 生体蛍光観察動画像の深度を考慮した深層学習による細胞追跡精度の改善, 嶋田 彩人,瀬尾 茂人,繁田 浩功,間下 以大,内田 穣,石井 優,松田 秀雄, 情報処理学会論文誌数理モデル化と応用(TOM), Vol. 12, No. 2, p. 82-91, 2019/07
  • In vivo Multicolor Imaging with Fluorescent Probes Revealed the Dynamics and Function of Osteoclast Proton Pumps, Masafumi Minoshima,Junichi Kikuta,Yuta Omori,Shigeto Seno,Riko Suehara,Hiroki Maeda,Hideo Matsuda,Masaru Ishii,Kazuya Kikuchi, ACS Central Science, Vol. 5, No. 6, p. 1059-1066, 2019/06
  • GPR31-dependent dendrite protrusion of intestinal CX3CR1(+) cells by bacterial metabolites, Morita Naoki,Umemoto Eiji,Fujita Setsuko,Hayashi Akio,Kikuta Junichi,Kimura Ikuo,Haneda Takeshi,Imai Toshio,Inoue Asuka,Mimuro Hitomi,Maeda Yuichi,Kayama Hisako,Okumura Ryu,Aoki Junken,Okada Nobuhiko,Kida Toshiyuki,Ishii Masaru,Nabeshima Ryusuke,Takeda Kiyoshi, NATURE, Vol. 566, No. 7742, p. 110-+, 2019/02/07
  • Imaging the Bone-Immune Cell Interaction in Bone Destruction., Hasegawa T,Kikuta J,Ishii M, Frontiers in immunology, Vol. 10, 2019
  • Roles of Enhancer RNAs in RANKL-induced Osteoclast Differentiation Identified by Genome-wide Cap-analysis of Gene Expression using CRISPR, Yukako Sakaguchi,Keizo Nishikawa,Shigeto Seno,Hideo Matsuda,Hiroshi Takayanagi,Masaru Ishii, Scientific Reports, Nature Publishing Group, Vol. 8, No. 1, 2018/12/01
  • Intravital imaging with two-photon microscopy reveals cellular dynamics in the ischeamia-reperfused rat heart., Ryohei Matsuura,Shigeru Miyagawa,Satsuki Fukushima,Takasumi Goto,Akima Harada,Yuri Shimozaki,Kazumasa Yamaki,Sho Sanami,Junichi Kikuta,Masaru Ishii,Yoshiki Sawa, Scientific reports, Vol. 8, No. 1, p. 15991-15991, 2018/10/30
  • Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation., Masaya Baba,Mitsuhiro Endoh,Wenjuan Ma,Hirofumi Toyama,Akiyoshi Hirayama,Keizo Nishikawa,Keiyo Takubo,Hiroyuki Hano,Hisashi Hasumi,Terumasa Umemoto,Michihiro Hashimoto,Nobuko Irie,Chiharu Esumi,Miho Kataoka,Naomi Nakagata,Tomoyoshi Soga,Masahiro Yao,Tomomi Kamba,Takashi Minami,Masaru Ishii,Toshio Suda, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 33, No. 10, p. 1785-1798, 2018/10
  • Presenilin 1 Regulates NF-κB Activation via Association with Breakpoint Cluster Region and Casein Kinase II., Tanaka Y,Sabharwal L,Ota M,Nakagawa I,Jiang JJ,Arima Y,Ogura H,Okochi M,Ishii M,Kamimura D,Murakami M, Journal of immunology (Baltimore, Md. : 1950), 2018/09
  • The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques., Takahiro Nagatake,Yumiko Shiogama,Asuka Inoue,Junichi Kikuta,Tetsuya Honda,Prabha Tiwari,Takayuki Kishi,Atsushi Yanagisawa,Yosuke Isobe,Naomi Matsumoto,Michiko Shimojou,Sakiko Morimoto,Hidehiko Suzuki,So-Ichiro Hirata,Pär Steneberg,Helena Edlund,Junken Aoki,Makoto Arita,Hiroshi Kiyono,Yasuhiro Yasutomi,Masaru Ishii,Kenji Kabashima,Jun Kunisawa, The Journal of allergy and clinical immunology, Vol. 142, No. 2, p. 470-484, 2018/08
  • In vivo visualisation of different modes of action of biological DMARDs inhibiting osteoclastic bone resorption., Yoshinobu Matsuura,Junichi Kikuta,Yuika Kishi,Tetsuo Hasegawa,Daisuke Okuzaki,Toru Hirano,Masafumi Minoshima,Kazuya Kikuchi,Atsushi Kumanogoh,Masaru Ishii, Annals of the rheumatic diseases, Vol. 77, No. 8, p. 1219-1225, 2018/08
  • Chiral cell sliding drives left-right asymmetric organ twisting., Mikiko Inaki,Ryo Hatori,Naotaka Nakazawa,Takashi Okumura,Tomoki Ishibashi,Junichi Kikuta,Masaru Ishii,Kenji Matsuno,Hisao Honda, eLife, Vol. 7, 2018/06/12
  • Claudin-3 Loss Causes Leakage of Sweat from the Sweat Gland to Contribute to the Pathogenesis of Atopic Dermatitis, Kosuke Yamaga,Hiroyuki Murota,Atsushi Tamura,Hirofumi Miyata,Masato Ohmi,Junichi Kikuta,Masaru Ishii,Sachiko Tsukita,Ichiro Katayama, Journal of Investigative Dermatology, Elsevier B.V., Vol. 138, No. 6, p. 1279-1287, 2018/06/01
  • Dynamic Analyses of the Short‐term Effects of Different Bisphosphonates Using Intravital Two‐photon Microscopy, Junichi Kikuta,Mai Shirazaki,Takao Sudo,Hiroki Mizuno,Akito Morimoto,Riko Suehara,Masafumi Minoshima,Kazuya Kikuchi,Masaru Ishii, JBMR PLUS, 2018/05
  • In vivo live imaging of bone cells, Hiroki Mizuno,Junichi Kikuta,Masaru Ishii, Histochemistry and Cell Biology, Springer Verlag, Vol. 149, No. 4, p. 417-422, 2018/04/01
  • In vivo imaging of T cell lymphoma infiltration process at the colon., Yoshibumi Ueda,Toshiyuki Ishiwata,Seiichi Shinji,Tomio Arai,Yoko Matsuda,Junko Aida,Naotoshi Sugimoto,Toshiro Okazaki,Junichi Kikuta,Masaru Ishii,Moritoshi Sato, Scientific reports, Vol. 8, No. 1, p. 3978-3978, 2018/03/05
  • Direct cell-cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo., Masayuki Furuya,Junichi Kikuta,Sayumi Fujimori,Shigeto Seno,Hiroki Maeda,Mai Shirazaki,Maki Uenaka,Hiroki Mizuno,Yoriko Iwamoto,Akito Morimoto,Kunihiko Hashimoto,Takeshi Ito,Yukihiro Isogai,Masafumi Kashii,Takashi Kaito,Shinsuke Ohba,Ung-Il Chung,Alexander C Lichtler,Kazuya Kikuchi,Hideo Matsuda,Hideki Yoshikawa,Masaru Ishii, Nature communications, Vol. 9, No. 1, p. 300-300, 2018/01/19
  • [Development of intravital bone tissue imaging and future perspectives of new lines of therapies for bone diseases.], Ishii M, Clinical calcium, Vol. 28, No. 2, p. 167-174, 2018
  • [Basis of intravital bone imaging.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 175-179, 2018
  • [Development of methodology for living bone imaging.], Mizuno H,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 181-185, 2018
  • [Intravital bone imaging:osteoclast.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 211-216, 2018
  • [In vivo imaging of osteoblasts.], Uenaka M,Mizuno H,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 217-222, 2018
  • [The effects of anti-bone-resorptive drugs analyzed by intravital bone imaging.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 237-242, 2018
  • [Analysis of the bone anabolic agent by intravital imaging technique.], Morimoto A,Kikuta J,Furuya M,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 243-248, 2018
  • Bone imaging: Osteoclast and osteoblast dynamics, Junichi Kikuta,Masaru Ishii, Methods in Molecular Biology, Humana Press Inc., Vol. 1763, p. 1-9, 2018
  • Intravital imaging of liver cell dynamics, Sayaka Matsumoto,Junichi Kikuta,Masaru Ishii, Methods in Molecular Biology, Humana Press Inc., Vol. 1763, p. 137-143, 2018
  • [Homeostasis and Disorder of Musculoskeletal System.Cellular dynamics in musculoskeletal system visualized by intravital imaging techniques.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 3, p. 367-371, 2018
  • Intravital imaging of the heart at the cellular level using two-photon microscopy, Ryohei Matsuura,Shigeru Miyagawa,Junichi Kikuta,Masaru Ishii,Yoshiki Sawa, Methods in Molecular Biology, Humana Press Inc., Vol. 1763, p. 145-151, 2018
  • Bone marrow cavity segmentation using graph-cuts with wavelet-based texture feature, Hironori Shigeta,Tomohiro Mashita,Junichi Kikuta,Shigeto Seno,Haruo Takemura,Masaru Ishii,Hideo Matsuda, JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, IMPERIAL COLLEGE PRESS, Vol. 15, No. 5, 2017/10
  • Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions., Takahiro Matsui,Hiroki Mizuno,Takao Sudo,Junichi Kikuta,Naotsugu Haraguchi,Jun-Ichiro Ikeda,Tsunekazu Mizushima,Hirofumi Yamamoto,Eiichi Morii,Masaki Mori,Masaru Ishii, Scientific reports, Vol. 7, No. 1, p. 6959-6959, 2017/07/31
  • Immunology proves a great success for treating systemic autoimmune diseases - a perspective on immunopharmacology: IUPHAR Review 23, Masaru Ishii, BRITISH JOURNAL OF PHARMACOLOGY, WILEY, Vol. 174, No. 13, p. 1875-1880, 2017/07
  • Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes, Shunsuke Kon,Kojiro Ishibashi,Hiroto Katoh,Sho Kitamoto,Takanobu Shirai,Shinya Tanaka,Mihoko Kajita,Susumu Ishikawa,Hajime Yamauchi,Yuta Yako,Tomoko Kamasaki,Tomohiro Matsumoto,Hirotaka Watanabe,Riku Egami,Ayana Sasaki,Atsuko Nishikawa,Ikumi Kameda,Takeshi Maruyama,Rika Narumi,Tomoko Morita,Yoshiteru Sasaki,Ryosuke Enoki,Sato Honma,Hiromi Imamura,Masanobu Oshima,Tomoyoshi Soga,Jun-ichi Miyazaki,Michael R. Duchen,Jin-Min Nam,Yasuhito Onodera,Shingo Yoshioka,Junichi Kikuta,Masaru Ishii,Masamichi Imajo,Eisuke Nishida,Yoichiro Fujioka,Yusuke Ohba,Toshiro Sato,Yasuyuki Fujita, NATURE CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 19, No. 5, p. 530-+, 2017/05
  • Roles for Cell-Cell Adhesion and Contact in Obesity- Induced Hepatic Myeloid Cell Accumulation and Glucose Intolerance, Yasutaka Miyachi,Kyoichiro Tsuchiya,Chikara Komiya,Kumiko Shiba,Noriko Shimazu,Shinobu Yamaguchi,Michiyo Deushi,Mizuko Osaka,Kouji Inoue,Yuta Sato,Sayaka Matsumoto,Junichi Kikuta,Kenjiro Wake,Masayuki Yoshida,Masaru Ishii,Yoshihiro Ogawa, CELL REPORTS, CELL PRESS, Vol. 18, No. 11, p. 2766-2779, 2017/03
  • [Update on recent progress in vitamin D research. The effects of vitamin D in autoinflammatory diseases.], Ao T,Kikuta J,Ishii M, Clinical calcium, Vol. 27, No. 11, p. 1551-1559, 2017
  • Imaging of bone and joint destruction, Junichi Kikuta,Masaru Ishii, Japanese Journal of Clinical Immunology, Japan Society for Clinical Immunology, Vol. 40, No. 5, p. 344-351, 2017
  • Imaging of inflammation and regeneration: a novel trend dissecting dynamic features of biological phenomena in vivo., Ishii M, Inflammation and regeneration, Vol. 37, 2017
  • 模様特徴量とグラフカットを利用した生体骨組織の骨髄腔の領域分割, 繁田 浩功,間下 以大,菊田 順一,瀬尾 茂人,石井 優,松田 秀雄, 2016/09
  • Real-time intravital imaging of pH variation associated with osteoclast activity, Hiroki Maeda,Toshiyuki Kowada,Junichi Kikuta,Masayuki Furuya,Mai Shirazaki,Shin Mizukami,Masaru Ishii,Kazuya Kikuchi, NATURE CHEMICAL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 12, No. 8, p. 579-+, 2016/08
  • Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5 beta complex in migrating cells, Boon Cheng Lim,Shinji Matsumoto,Hideki Yamamoto,Hiroki Mizuno,Junichi Kikuta,Masaru Ishii,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 129, No. 16, p. 3115-3129, 2016/08
  • Cell-cycle-controlled radiation therapy was effective for treating a murine malignant melanoma cell line in vitro and in vivo, Keisuke Otani,Yoko Naito,Yukako Sakaguchi,Yuji Seo,Yutaka Takahashi,Junichi Kikuta,Kazuhiko Ogawa,Masaru Ishii, Scientific Reports, NATURE PUBLISHING GROUP, Vol. 6, 2016/08
  • Intravital imaging technology reveals immune system dynamics in vivo, Masaru Ishii, ALLERGOLOGY INTERNATIONAL, JAPANESE SOCIETY ALLERGOLOGY, Vol. 65, No. 3, p. 225-227, 2016/07
  • ウェーブレット特徴量を用いた生体骨組織の骨髄腔の領域分割手法, 繁田浩功,間下以大,菊田順一,瀬尾茂人,竹村治雄,松田秀雄,石井優, 2016/06
  • Intercellular Communication between Keratinocytes and Fibroblasts Induces Local Osteoclast Differentiation: a Mechanism Underlying Cholesteatoma-Induced Bone Destruction, Yoriko Iwamoto,Keizo Nishikawa,Ryusuke Imai,Masayuki Furuya,Maki Uenaka,Yumi Ohta,Tetsuo Morihana,Saori Itoi-Ochi,Josef M. Penninger,Ichiro Katayama,Hidenori Inohara,Masaru Ishii, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 36, No. 11, p. 1610-1620, 2016/06
  • [Analysis of bone tissues by intravital imaging]., Hiroki Mizuno,Erika Yamashita,Masaru Ishii, Clinical calcium, Vol. 26, No. 5, p. 729-34, 2016/05
  • Intravital imaging of the cellular dynamics of LysM-positive cells in a murine corneal suture model, Mayumi Ueta,Ayaka Koga,Junichi Kikuta,Keiko Yamada,Sachi Kojima,Katsuhiko Shinomiya,Masaru Ishii,Shigeru Kinoshita, BRITISH JOURNAL OF OPHTHALMOLOGY, BMJ PUBLISHING GROUP, Vol. 100, No. 3, p. 432-435, 2016/03
  • Visualization of Intravital Immune Cell Dynamics After Conjunctival Surgery Using Multiphoton Microscopy, Sachi Kojima,Toshihiro Inoue,Junichi Kikuta,Masayuki Furuya,Ayaka Koga,Tomokazu Fujimoto,Mayumi Ueta,Shigeru Kinoshita,Masaru Ishii,Hidenobu Tanihara, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Vol. 57, No. 3, p. 1207-1212, 2016/03
  • Involvement of Receptor Activator of Nuclear Factor-B Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts, Noriko Takegahara,Hyunsoo Kim,Hiroki Mizuno,Asako Sakaue-Sawano,Atsushi Miyawaki,Michio Tomura,Osami Kanagawa,Masaru Ishii,Yongwon Choi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 291, No. 7, p. 3439-3454, 2016/02
  • Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility, Akira Takeda,Daichi Kobayashi,Keita Aoi,Naoko Sasaki,Yuki Sigiura,Hidemitsu Igarashi,Kazuo Tohya,Asuka Inoue,Erina Hata,Noriyuki Akahoshi,Haruko Hayasaka,Junichi Kikuta,Elke Scandella,Brukhard Ludewig,Satoshi Ishii,Junken Aoki,Makoto Suematsu,Masaru Ishii,Kiyoshi Takeda,Sirpa Jalkanen,Masayuki Miyasaka,Eiji Umemoto, ELIFE, ELIFE SCIENCES PUBLICATIONS LTD, Vol. 5, 2016/02
  • A Bone Marrow Cavity Segmentation Method using Wavelet-based Texture Feature, Hironori Shigeta,Tomohiro Mashita,Junichi Kikutat,Shigeto Seno,Haruo Takemura,Hideo Matsuda,Masaru Ishii, 2016 23RD INTERNATIONAL CONFERENCE ON PATTERN RECOGNITION (ICPR), IEEE COMPUTER SOC, p. 2133-2138, 2016
  • Intravital imaging of Ca2+ signals in lymphocytes of Ca2+ biosensor transgenic mice: indication of autoimmune diseases before the pathological onset, Soichiro Yoshikawa,Takako Usami,Junichi Kikuta,Masaru Ishii,Tetsuo Sasano,Koji Sugiyama,Tetsushi Furukawa,Eiji Nakasho,Hiroshi Takayanagi,Thomas F. Tedder,Hajime Karasuyama,Atsushi Miyawaki,Takahiro Adachi, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 6, 2016/01
  • Dynamic analysis of immune inflammation and bone destruction by intravital imaging., Kikuta J,Ishii M, Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, Vol. 39, No. 2, p. 124-129, 2016
  • Adipose tissue macrophages induce PPAR gamma- high FOXP3+regulatory T cells, Toshiharu Onodera,Atsunori Fukuhara,Myoung Ho Jang,Jihoon Shin,Keita Aoi,Junichi Kikuta,Michio Otsuki,Masaru Ishii,Iichiro Shimomura, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 5, 2015/11
  • Trafficking of Osteoclast Precursors, Junichi Kikuta,Erin Nevius,Masaru Ishii,João P. Pereira, Osteoimmunology: Interactions of the Immune and Skeletal Systems: Second Edition, Elsevier Inc., p. 25-40, 2015/10/06
  • Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing, Nathan P. Manes,Bastian R. Angermann,Marijke Koppenol-Raab,Eunkyung An,Virginie H. Sjoelund,Jing Sun,Masaru Ishii,Ronald N. Germain,Martin Meier-Schellersheim,Aleksandra Nita-Lazar, MOLECULAR & CELLULAR PROTEOMICS, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 14, No. 10, p. 2661-2681, 2015/10
  • Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis, Erin Nevius,Flavia Pinho,Meera Dhodapkar,Huiyan Jin,Kristina Nadrah,Mark C. Horowitz,Junichi Kikuta,Masaru Ishii,Joao P. Pereira, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 212, No. 11, p. 1931-1946, 2015/10
  • The expanding role of immunopharmacology: IUPHAR Review 16, Ekaterini Tiligada,Masaru Ishii,Carlo Riccardi,Michael Spedding,Hans-Uwe Simon,Mauro Martins Teixeira,Mario Landys Chovel Cuervo,Stephen T. Holgate,Francesca Levi-Schaffer, BRITISH JOURNAL OF PHARMACOLOGY, WILEY, Vol. 172, No. 17, p. 4217-4227, 2015/09
  • Significance of Polypyrimidine Tract-Binding Protein 1 Expression in Colorectal Cancer., Hidekazu Takahashi,Junichi Nishimura,Yoshinori Kagawa,Yoshihiro Kano,Yusuke Takahashi,Xin Wu,Masayuki Hiraki,Atsushi Hamabe,Masamitsu Konno,Naotsugu Haraguchi,Ichiro Takemasa,Tsunekazu Mizushima,Masaru Ishii,Koshi Mimori,Hideshi Ishii,Yuichiro Doki,Masaki Mori,Hirofumi Yamamoto, Molecular cancer therapeutics, Vol. 14, No. 7, p. 1705-16, 2015/07
  • コンポーネントツリーを用いたグローバルデータアソシエーションによる細胞追跡手法, Kohei Kurashige,Shigeto Seno,Tomohiro Mashita,Junichi Kikuta,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2015/06
  • [Frontiers in Live Bone Imaging Researches. Intravital imaging of osteoclast dynamics]., Kikuta J,Ishii M, Clinical calcium, Vol. 25, No. 6, p. 815-822, 2015/06
  • [Frontiers in Live Bone Imaging Researches. In vivo imaging of osteoblasts]., Furuya M,Ishii M, Clinical calcium, Vol. 25, No. 6, p. 823-830, 2015/06
  • [Frontiers in Live Bone Imaging Researches. In vivo imaging of bone marrow microenvironment]., Mizuno H,Ishii M, Clinical calcium, Vol. 25, No. 6, p. 831-836, 2015/06
  • [Frontiers in Live Bone Imaging Researches. Novel drug discovery by means of intravital bone imaging technology]., Ishii M, Clinical calcium, Vol. 25, No. 6, p. 907-913, 2015/06
  • [Intravital multiphoton imaging of live bone tissues revealing hematopoietic cell dynamics in vivo]., Mizuno H,Kikuta J,Furuya M,Ishii M, [Rinsho ketsueki] The Japanese journal of clinical hematology, Vol. 56, No. 6, p. 594-600, 2015/06
  • [In vivo imaging of bones--New era for research of bones]., Ishii M, Clinical calcium, Vol. 25, No. 6, 2015/06
  • Intravital bone imaging by two-photon excitation microscopy to identify osteocytic osteolysis in vivo, Hiroshige Sano,Junichi Kikuta,Masayuki Furuya,Naoki Kondo,Naoto Endo,Masaru Ishii, BONE, ELSEVIER SCIENCE INC, Vol. 74, p. 134-139, 2015/05
  • Visualized macrophage dynamics and significance of S100A8 in obese fat, Ryohei Sekimoto,Shiro Fukuda,Norikazu Maeda,Yu Tsushima,Keisuke Matsuda,Takuya Mori,Hideaki Nakatsuji,Hitoshi Nishizawa,Ken Kishida,Junichi Kikuta,Yumiko Maijima,Tohru Funahashi,Masaru Ishii,Iichiro Shimomura, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 112, No. 16, p. E2058-E2066, 2015/04
  • A Bone Marrow Recognition Method for Bone Tissue Images using Wavelet Transform, Hironori Shigeta,Tomohiro Mashita,Takeshi Kaneko,Junichi Kikuta,Shigeto Senoo,Haruo Takemura,Hideo Matsuda,Masaru Ishii, 2015/03
  • グラフカットを用いた骨髄腔画像の領域分割, 宇佐見 潤,繁田 浩功,間下 以大,黒田 嘉宏,菊田 順一,瀬尾 茂人,石井 優,松田 秀雄,竹村 治雄, 情報処理学会論文誌 数理モデル化と応用, Vol. 8, No. 1, p. 18-27, 2015/03
  • RFPL4A Increases the G(1) Population and Decreases Sensitivity to Chemotherapy in Human Colorectal Cancer Cells, Atsushi Naito,Hirofumi Yamamoto,Yoshinori Kagawa,Yoko Naito,Daisuke Okuzaki,Keisuke Otani,Yoriko Iwamoto,Sakae Maeda,Junichi Kikuta,Keizo Nishikawa,Mamoru Uemura,Junichi Nishimura,Taishi Hata,Ichiro Takemasa,Tsunekazu Mizushima,Hideshi Ishii,Yuichiro Doki,Masaki Mori,Masaru Ishii, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 290, No. 10, p. 6326-6337, 2015/03
  • DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine-producing metabolic pathway, Keizo Nishikawa,Yoriko Iwamoto,Yasuhiro Kobayashi,Fumiki Katsuoka,Shin-ichi Kawaguchi,Tadayuki Tsujita,Takashi Nakamura,Shigeaki Kato,Masayuki Yamamoto,Hiroshi Takayanagi,Masaru Ishii, NATURE MEDICINE, NATURE PUBLISHING GROUP, Vol. 21, No. 3, p. 281-+, 2015/03
  • [Current Topics on Vitamin D. The effects of vitamin D on the immune system]., Kikuta J,Ishii M, Clinical calcium, Vol. 25, No. 3, p. 359-365, 2015/03
  • Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient, Xiaowen Liu,Tao Yang,Koya Suzuki,Sachiko Tsukita,Masaru Ishii,Shuping Zhou,Gang Wang,Luyang Cao,Feng Qian,Shalina Taylor,Myung-Jin Oh,Irena Levitan,Richard D. Ye,Graeme K. Carnegie,Yong Zhao,Asrar B. Malik,Jingsong Xu, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 212, No. 2, p. 267-280, 2015/02
  • Transplanted Bone Marrow-Derived Circulating PDGFR alpha(+) Cells Restore Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa Mouse Skin Graft, Shin Iinuma,Eriko Aikawa,Katsuto Tamai,Ryo Fujita,Yasushi Kikuchi,Takenao Chino,Junichi Kikuta,John A. McGrath,Jouni Uitto,Masaru Ishii,Hajime Iizuka,Yasufumi Kaneda, JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 194, No. 4, p. 1996-2003, 2015/02
  • 生体骨組織における骨髄腔画像のウェーブレット変換を用いた骨髄腔領域の認識手法, 繁田 浩功,間下 以大,金子 雄,菊田 順一,瀬尾 茂人,竹村 治雄,松田 秀雄,石井 優, 2015/01
  • Sweat, the driving force behind normal skin: An emerging perspective on functional biology and regulatory mechanisms, Hiroyuki Murota,Saki Matsui,Emi Ono,Akiko Kijima,Junichi Kikuta,Masaru Ishii,Ichiro Katayama, JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER IRELAND LTD, Vol. 77, No. 1, p. 3-10, 2015/01
  • Improvement approach of cell tracking accuracy by using inter-frame information, Kohei Kurashige,Shigeto Seno,Tomohiro Mashita,Junichi Kikuta,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2014/10
  • An automatic event detection method using semi-supervised learning for time-lapse imaging data, Kojiro Fukuda,Shigeto Seno,Tomohiro Mashita,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2014/10
  • A Segmentation Method for Bone Marrow Cavity Image Using Graph-Cuts, Tomohiro Mashita,Jun Usami,Hironori Shigeta,Yoshihiro Kuroda,Junichi Kikuta,Shigeto Senoo,Masaru Ishii,Hideo Matsuda,Haruo Takemura, 2014/09
  • A Graph Cuts Image Segmentation Method for Quantifying Barrier Permeation in Bone Tissue, Hironori Shigeta,Tomohiro Mashita,Takeshi Kaneko,Junichi Kikuta,Shigeto Senoo,Haruo Takemura,Hideo Matsuda,Masaru Ishii, 2014/09
  • Interferon-α acts on the S/G2/M phases to induce apoptosis in the G1 phase of an IFNAR2-expressing hepatocellular carcinoma cell line., Sakae Maeda,Hiroshi Wada,Yoko Naito,Hiroaki Nagano,Szandor Simmons,Yoshinori Kagawa,Atsushi Naito,Junichi Kikuta,Taeko Ishii,Yoshito Tomimaru,Naoki Hama,Koichi Kawamoto,Shogo Kobayashi,Hidetoshi Eguchi,Koji Umeshita,Hideshi Ishii,Yuichiro Doki,Masaki Mori,Masaru Ishii, The Journal of biological chemistry, Vol. 289, No. 34, p. 23786-95, 2014/08/22
  • Left-right asymmetry is formed in individual cells by intrinsic cell chirality, Ryo Hatori,Tadashi Ando,Takeshi Sasamura,Naotaka Nakazawa,Mitsutoshi Nakamura,Kiichiro Taniguchi,Shunya Hozumi,Junichi Kikuta,Masaru Ishii,Kenji Matsuno, MECHANISMS OF DEVELOPMENT, ELSEVIER SCIENCE BV, Vol. 133, p. 146-162, 2014/08
  • [Bone metabolism and cardiovascular function update. Relationship between immune and vascular system in bone tissues]., Kikuta J,Ishii M, Clinical calcium, Vol. 24, No. 7, p. 63-68, 2014/07
  • Filamin acts as a key regulator in epithelial defence against transformed cells, Mihoko Kajita,Kaoru Sugimura,Atsuko Ohoka,Jemima Burden,Hitomi Suganuma,Masaya Ikegawa,Takashi Shimada,Tetsuya Kitamura,Masanobu Shindoh,Susumu Ishikawa,Sayaka Yamamoto,Sayaka Saitoh,Yuta Yako,Ryosuke Takahashi,Takaharu Okajima,Junichi Kikuta,Yumiko Maijima,Masaru Ishii,Masazumi Tada,Yasuyuki Fujita, NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, Vol. 5, 2014/07
  • Olopatadine hydrochloride restores histamine-induced impaired sweating, Saki Matsui,Hiroyuki Murota,Emi Ono,Junichi Kikuta,Masaru Ishii,Ichiro Katayama, JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER IRELAND LTD, Vol. 74, No. 3, p. 260-261, 2014/06
  • Development of an in vitro culture method for stepwise differentiation of mouse embryonic stem cells and induced pluripotent stem cells into mature osteoclasts, Keizo Nishikawa,Yoriko Iwamoto,Masaru Ishii, JOURNAL OF BONE AND MINERAL METABOLISM, SPRINGER JAPAN KK, Vol. 32, No. 3, p. 331-336, 2014/05
  • Sphingosine-1-Phosphate: a Master Regulator of Lymphocyte Egress and Immunity, Szandor Simmons,Masaru Ishii, ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, SPRINGER BASEL AG, Vol. 62, No. 2, p. 103-115, 2014/04
  • A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures, Shinji Matsumoto,Shinsuke Fujii,Akira Sato,Souji Ibuka,Yoshinori Kagawa,Masaru Ishii,Akira Kikuchi, EMBO JOURNAL, WILEY-BLACKWELL, Vol. 33, No. 7, p. 702-718, 2014/04
  • [Bone and Stem Cells. Intravital imaging of bone marrow microenvironment]., Mizuno H,Kikuta J,Ishii M, Clinical calcium, Vol. 24, No. 4, p. 541-546, 2014/04
  • Generation of colonic IgA-secreting cells in the caecal patch, Kazunori Masahata,Eiji Umemoto,Hisako Kayama,Manato Kotani,Shota Nakamura,Takashi Kurakawa,Junichi Kikuta,Kazuyoshi Gotoh,Daisuke Motooka,Shintaro Sato,Tomonori Higuchi,Yoshihiro Baba,Tomohiro Kurosaki,Makoto Kinoshita,Yosuke Shimada,Taishi Kimura,Ryu Okumura,Akira Takeda,Masaru Tajima,Osamu Yoshie,Masahiro Fukuzawa,Hiroshi Kiyono,Sidonia Fagarasan,Tetsuya Iida,Masaru Ishii,Kiyoshi Takeda, NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, Vol. 5, 2014/04
  • Lysophosphatidic Acid Receptor Type 1 (LPA(1)) Plays a Functional Role in Osteoclast Differentiation and Bone Resorption Activity, Marion David,Irma Machuca-Gayet,Junichi Kikuta,Penelope Ottewell,Fuka Mima,Raphael Leblanc,Edith Bonnelye,Johnny Ribeiro,Ingunn Holen,Ruben Lopez Vales,Pierre Jurdic,Jerold Chun,Philippe Clezardin,Masaru Ishii,Olivier Peyruchaud, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 289, No. 10, p. 6551-6564, 2014/03
  • Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress., Koyu Ito,Junko Morimoto,Akio Kihara,Yutaka Matsui,Daisuke Kurotaki,Masashi Kanayama,Szandor Simmons,Masaru Ishii,Dean Sheppard,Akinori Takaoka,Toshimitsu Uede, Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 8, p. 3080-5, 2014/02/25
  • Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo., Cui G,Hara T,Simmons S,Wagatsuma K,Abe A,Miyachi H,Kitano S,Ishii M,Tani-ichi S,Ikuta K, Proc Natl Acad Sci USA, Vol. 160, No. 2, p. 109-112, 2014/02
  • Dynamic Analysis of Histamine-Mediated Attenuation of Acetylcholine-Induced Sweating via GSK3 beta Activation, Saki Matsui,Hiroyuki Murota,Aya Takahashi,Lingli Yang,Jeong-Beom Lee,Kouta Omiya,Masato Ohmi,Junichi Kikuta,Masaru Ishii,Ichiro Katayama, JOURNAL OF INVESTIGATIVE DERMATOLOGY, NATURE PUBLISHING GROUP, Vol. 134, No. 2, p. 326-334, 2014/02
  • Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo, Guangwei Cui,Takahiro Hara,Szandor Simmons,Keisuke Wagatsuma,Akifumi Abe,Hitoshi Miyachi,Satsuki Kitano,Masaru Ishii,Shizue Tani-ichi,Koichi Ikuta, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 111, No. 5, p. 1915-1920, 2014/02
  • Dynamic Visualization of Dendritic Cell-Antigen Interactions in the Skin Following Transcutaneous Immunization, Teerawan Rattanapak,James C. Birchall,Katherine Young,Atsuko Kubo,Sayumi Fujimori,Masaru Ishii,Sarah Hook, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 9, No. 2, 2014/02
  • LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis, Takahiro Nakamura,Junji Hamuro,Mikiro Takaishi,Szandor Simmons,Kazuichi Maruyama,Andrea Zaffalon,Adam J. Bentley,Satoshi Kawasaki,Maho Nagata-Takaoka,Nigel J. Fullwood,Satoshi Itami,Shigetoshi Sano,Masaru Ishii,Yann Barrandon,Shigeru Kinoshita, JOURNAL OF CLINICAL INVESTIGATION, AMER SOC CLINICAL INVESTIGATION INC, Vol. 124, No. 1, p. 385-397, 2014/01
  • Intravital multiphoton microscopy for dissecting cellular dynamics in arthritic inflammation and bone destruction., Kikuta J,Ishii M, Methods in molecular biology (Clifton, N.J.), Vol. 1142, p. 1-10, 2014
  • 混合正規分布モデルを用いた経時観測蛍光画像からの細胞核の検出と追跡手法, 瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 情報処理学会論文誌数理モデル化と応用, Vol. 6, No. 3, p. 140-150, 2013/12
  • Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy, Teerawan Rattanapak,James Birchall,Katherine Young,Masaru Ishii,Igor Meglinski,Thomas Rades,Sarah Hook, JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE BV, Vol. 172, No. 3, p. 894-903, 2013/12
  • Cell Cycle-Dependent Rho GTPase Activity Dynamically Regulates Cancer Cell Motility and Invasion In Vivo, Yoshinori Kagawa,Shinji Matsumoto,Yuji Kamioka,Koshi Mimori,Yoko Naito,Taeko Ishii,Daisuke Okuzaki,Naohiro Nishida,Sakae Maeda,Atsushi Naito,Junichi Kikuta,Keizo Nishikawa,Junichi Nishimura,Naotsugu Haraguchi,Ichiro Takemasa,Tsunekazu Mizushima,Masataka Ikeda,Hirofumi Yamamoto,Mitsugu Sekimoto,Hideshi Ishii,Yuichiro Doki,Michiyuki Matsuda,Akira Kikuchi,Masaki Mori,Masaru Ishii, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 8, No. 12, 2013/12
  • [Dynamics of bone resorption analyzed by intravital imaging]., Kikuta J,Ishii M, Clinical calcium, Vol. 23, No. 11, p. 1627-1633, 2013/11
  • Sphingosine-1-phosphate and chemokines in the control of osteoclast precursors migration visualized by intravital multiphoton microscopy, Junichi Kikuta,Atsuko Kubo,Masaru Ishii, Osteoimmunology: Interactions of the immune and skeletal systems, p. 73-79, 2013/10/01
  • 経時観測蛍光画像からのモーションヒストリーイメージを用いた細胞分裂の検出方法, 福田浩二郎,瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 2013/08
  • Global Data Associationによる経時観察画像における破骨前駆細胞の自動追跡手法, 尾野貴広,瀬尾茂人,間下以大,竹中要一,石井優,松田秀雄, 2013/07
  • Jumonji/Arid1b (Jarid1b) protein modulates human esophageal cancer cell growth., Yoshihiro Kano,Masamitsu Konno,Katsuya Ohta,Naotsugu Haraguchi,Shimpei Nishikawa,Yoshinori Kagawa,Atsushi Hamabe,Shinichiro Hasegawa,Hisataka Ogawa,Takahito Fukusumi,Yuko Noguchi,Miyuki Ozaki,Toshihiro Kudo,Daisuke Sakai,Taroh Satoh,Masaru Ishii,Eiichi Mizohata,Takeshi Inoue,Masaki Mori,Yuichiro Doki,Hideshi Ishii, Molecular and clinical oncology, Vol. 1, No. 4, p. 753-757, 2013/07
  • Layer v cortical neurons require microglial support for survival during postnatal development, Masaki Ueno,Yuki Fujita,Tatsuhide Tanaka,Yuka Nakamura,Junichi Kikuta,Masaru Ishii,Toshihide Yamashita, Nature Neuroscience, Vol. 16, No. 5, p. 543-551, 2013/05
  • Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D, Junichi Kikuta,Shunsuke Kawamura,Fumie Okiji,Mai Shirazaki,Sadaoki Sakai,Hitoshi Saito,Masaru Ishii, Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, Vol. 110, No. 17, p. 7009-7013, 2013/04/23
  • Depletion of JARID1B induces cellular senescence in human colorectal cancer., Katsuya Ohta,Naotsugu Haraguchi,Yoshihiro Kano,Yoshinori Kagawa,Masamitsu Konno,Shimpei Nishikawa,Atsushi Hamabe,Shinichiro Hasegawa,Hisataka Ogawa,Takahito Fukusumi,Mamoru Uemura,Junichi Nishimura,Taishi Hata,Ichiro Takemasa,Tsunekazu Mizushima,Yuko Noguchi,Miyuki Ozaki,Toshihiro Kudo,Daisuke Sakai,Taroh Satoh,Miwa Fukami,Masaru Ishii,Hirofumi Yamamoto,Yuichiro Doki,Masaki Mori,Hideshi Ishii, International journal of oncology, Vol. 42, No. 4, p. 1212-8, 2013/04
  • [Analysis of bone tissues by using fluorescent imaging]., Kikuta J,Ishii M, Clinical calcium, Vol. 23, No. 3, p. 355-360, 2013/03
  • Osteoclast migration, differentiation and function: Novel therapeutic targets for rheumatic diseases, Junichi Kikuta,Masaru Ishii, Rheumatology (United Kingdom), Vol. 52, No. 2, p. 226-234, 2013/02
  • Dynamic visualization of RANKL and Th17-mediated osteoclast function., Junichi Kikuta,Yoh Wada,Toshiyuki Kowada,Ze Wang,Ge-Hong Sun-Wada,Issei Nishiyama,Shin Mizukami,Nobuhiko Maiya,Hisataka Yasuda,Atsushi Kumanogoh,Kazuya Kikuchi,Ronald N Germain,Masaru Ishii, The Journal of clinical investigation, Vol. 123, No. 2, p. 866-73, 2013/02
  • CognitionMaster: an object-based image analysis framework, Stephan Wienert,Daniel Heim,Manato Kotani,Bjoern Lindequist,Albrecht Stenzinger,Masaru Ishii,Peter Hufnagl,Michael Beil,Manfred Dietel,Carsten Denkert,Frederick Klauschen, DIAGNOSTIC PATHOLOGY, BIOMED CENTRAL LTD, Vol. 8, 2013/02
  • Systemic circulation and bone recruitment of osteoclast precursors tracked by using fluorescent imaging techniques, Manato Kotani,Junichi Kikuta,Frederick Klauschen,Takenao Chino,Yasuhiro Kobayashi,Hisataka Yasuda,Katsuto Tamai,Atsushi Miyawaki,Osami Kanagawa,Michio Tomura,Masaru Ishii, Journal of Immunology, Vol. 190, No. 2, p. 605-612, 2013/01/15
  • Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis., Ishii M,Kikuta J, Biochimica et biophysica acta, Vol. 1831, No. 1, p. 223-227, 2013/01
  • Dynamic live imaging of bone: Opening a new era with 'bone histodynametry', Masaru Ishii,Sayumi Fujimori,Takeshi Kaneko,Junichi Kikuta, Journal of Bone and Mineral Metabolism, Vol. 31, No. 5, p. 507-511, 2013
  • 多色蛍光イメージングによる経時観測データのための細胞追跡手法, 瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 2012/12
  • 多色蛍光タイムラプスイメージングによる細胞周期観測データのための細胞自動追跡手法, 瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 2012/11
  • Automatic cell tracking for time-lapse fluorescent images of cell cycle, Shigeto Seno,Sakae Maeda,Tomohiro Mashita,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2012/10
  • A cell-tracking method for time-lapse multicolor fluorescent images, Shigeto Seno,Tomohiro Mashita,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2012/09
  • Recent Advances in Intravital Imaging of Dynamic Biological Systems, Junichi Kikuta,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 119, No. 3, p. 193-197, 2012/07
  • The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice, Shigetomo Fukuhara,Szandor Simmons,Shunsuke Kawamura,Asuka Inoue,Yasuko Orba,Takeshi Tokudome,Yuji Sunden,Yuji Arai,Kazumasa Moriwaki,Junji Ishida,Akiyoshi Uemura,Hiroshi Kiyonari,Takaya Abe,Akiyoshi Fukamizu,Masanori Hirashima,Hirofumi Sawa,Junken Aoki,Masaru Ishii,Naoki Mochizuki, JOURNAL OF CLINICAL INVESTIGATION, AMER SOC CLINICAL INVESTIGATION INC, Vol. 122, No. 4, p. 1416-1426, 2012/04
  • How do contemporary imaging techniques contribute to basic and clinical rheumatology?, Masaru Ishii, ANNALS OF THE RHEUMATIC DISEASES, B M J PUBLISHING GROUP, Vol. 71, p. 67-69, 2012/04
  • Intestinal CX3C chemokine receptor 1(high) (CX(3)CR1(high)) myeloid cells prevent T-cell-dependent colitis, Hisako Kayama,Yoshiyasu Ueda,Yukihisa Sawa,Seong Gyu Jeon,Ji Su Ma,Ryu Okumura,Atsuko Kubo,Masaru Ishii,Taku Okazaki,Masaaki Murakami,Masahiro Yamamoto,Hideo Yagita,Kiyoshi Takeda, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 109, No. 13, p. 5010-5015, 2012/03
  • [Intravital imaging of cancer cell dynamics]., Kagawa Y,Maeda S,Mori M,Ishii M, Nihon Geka Gakkai zasshi, Vol. 113, No. 2, p. 171-176, 2012/03
  • Use of intravital microscopy and in vitro chemotaxis assays to study the roles of sphingosine-1-phosphate in bone homeostasis, Taeko Ishii,Shunsuke Kawamura,Issei Nishiyama,Junichi Kikuta,Masaru Ishii, Methods in Molecular Biology, Vol. 874, p. 129-139, 2012
  • [Bone and calcium update; bone research update. Trafficking of osteoclast precursors visualized by intravital imaging technology]., Kotani M,Kikuta J,Ishii M, Clinical calcium, Vol. 21, No. 12, p. 85-91, 2011/12
  • In Vivo Fluorescence Imaging of Bone-Resorbing Osteoclasts, Toshiyuki Kowada,Junichi Kikuta,Atsuko Kubo,Masaru Ishii,Hiroki Maeda,Shin Mizukami,Kazuya Kikuchi, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, Vol. 133, No. 44, p. 17772-17776, 2011/11
  • [In vivo imaging of mature osteoclasts and RANKL signaling]., Kikuta J,Ishii M, Clinical calcium, Vol. 21, No. 8, p. 1181-1185, 2011/08
  • S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis, Junichi Kikuta,Kaori Iwai,Yukihiko Saeki,Masaru Ishii, RHEUMATOLOGY INTERNATIONAL, SPRINGER HEIDELBERG, Vol. 31, No. 7, p. 967-969, 2011/07
  • The role of sphingosine 1-phosphate in migration of osteoclast precursors; an application of intravital two-photon microscopy, Taeko Ishii,Yutaka Shimazu,Issei Nishiyama,Junichi Kikuta,Masaru Ishii, MOLECULES AND CELLS, KOREAN SOC MOLECULAR & CELLULAR BIOLOGY, Vol. 31, No. 5, p. 399-403, 2011/05
  • PDGFR alpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia, Katsuto Tamai,Takehiko Yamazaki,Takenao Chino,Masaru Ishii,Satoru Otsuru,Yasushi Kikuchi,Shin Iinuma,Kotaro Saga,Keisuke Nimura,Takashi Shimbo,Noriko Umegaki,Ichiro Katayama,Jun-ichi Miyazaki,Junji Takeda,John A. McGrath,Jouni Uitto,Yasufumi Kaneda, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 108, No. 16, p. 6609-6614, 2011/04
  • Intravital two-photon imaging: a versatile tool for dissecting the immune system, Taeko Ishii,Masaru Ishii, ANNALS OF THE RHEUMATIC DISEASES, B M J PUBLISHING GROUP, Vol. 70, p. I113-I115, 2011/03
  • [Encounter of cancer cells with bone. In vivo imaging of osteoclasts and their precursors in intact bone tissues]., Kikuta J,Kawamura S,Ishii M, Clinical calcium, Vol. 21, No. 3, p. 372-378, 2011/03
  • Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo, Masaru Ishii,Junichi Kikuta,Yutaka Shimazu,Martin Meier-Schellersheim,Ronald N. Germain, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 207, No. 13, p. 2793-2798, 2010/12
  • ANG II inhibits insulin-mediated production of PI 3,4,5-trisphosphates via a Ca2+-dependent but PKC-independent pathway in the cardiomyocytes, Masashi Ikushima,Masaru Ishii,Mitsuru Ohishi,Koichi Yamamoto,Toshio Ogihara,Hiromi Rakugi,Yoshihisa Kurachi, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 299, No. 3, p. H680-H689, 2010/09
  • Cellular modelling: experiments and simulation to develop a physiological model of G-protein control of muscarinic K+ channels in mammalian atrial cells, Shingo Murakami,Shingo Suzuki,Masaru Ishii,Atsushi Inanobe,Yoshihisa Kurachi, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, ROYAL SOC, Vol. 368, No. 1921, p. 2983-3000, 2010/06
  • A case of Mikulicz's disease with Th2-biased cytokine profile: possible feature discriminable from Sjogren's syndrome, Eriko Kudo-Tanaka,Shinichi Nakatsuka,Toru Hirano,Mari Kawai,Yoshinori Katada,Masato Matsushita,Shiro Ohshima,Masaru Ishii,Kunio Miyatake,Toshio Tanaka,Yukihiko Saeki, MODERN RHEUMATOLOGY, SPRINGER, Vol. 19, No. 6, p. 691-695, 2009/12
  • Visualization and Identification of IL-7 Producing Cells in Reporter Mice, Renata I. Mazzucchelli,Soren Warming,Scott M. Lawrence,Masaru Ishii,Mehrnoosh Abshari,A. Valance Washington,Lionel Feigenbaum,Andrew C. Warner,Davis J. Sims,Wen Qing Li,Julie A. Hixon,Daniel H. D. Gray,Benjamin E. Rich,Matthew Morrow,Miriam R. Anver,James Cherry,Dieter Naf,Lawrence R. Sternberg,Daniel W. McVicar,Andrew G. Farr,Ronald N. Germain,Keith Rogers,Nancy A. Jenkins,Neal G. Copeland,Scott K. Durum, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 4, No. 11, 2009/11
  • Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis, Masaru Ishii,Jackson G. Egen,Frederick Klauschen,Martin Meier-Schellersheim,Yukihiko Saeki,Jean Vacher,Richard L. Proia,Ronald N. Germain, NATURE, NATURE PUBLISHING GROUP, Vol. 458, No. 7237, p. 524-U8, 2009/03
  • Quantifying cellular interaction dynamics in 3D fluorescence microscopy data, Frederick Klauschen,Masaru Ishii,Hai Qi,Marc Bajenoff,Jackson G. Egen,Ronald N. Germain,Martin Meier-Schellersheim, NATURE PROTOCOLS, NATURE PUBLISHING GROUP, Vol. 4, No. 9, p. 1305-1312, 2009
  • [System biology]., Ishii M,Kurachi Y, Nihon yakurigaku zasshi. Folia pharmacologica Japonica, Vol. 126, No. 2, p. 117-120, 2005/08
  • Assays of RGS protein modulation by phosphatidylinositides and calmodulin, M Ishii,Y Kurachi, REGULATORS OF G-PROTEIN SIGNALING, PART A, ELSEVIER ACADEMIC PRESS INC, Vol. 389, p. 105-118, 2004
  • Assays of RGS protein modulation by phosphatidylinositides and calmodulin, M Ishii,Y Kurachi, REGULATORS OF G-PROTEIN SIGNALING, PART A, ELSEVIER ACADEMIC PRESS INC, Vol. 389, p. 105-118, 2004
  • Cell signal control of the G protein-gated potassium channel and its subcellular localization, Y Kurachi,M Ishii, JOURNAL OF PHYSIOLOGY-LONDON, BLACKWELL PUBLISHING LTD, Vol. 554, No. 2, p. 285-294, 2004/01
  • Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall, H Hibino,K Higashi,A Fujita,K Iwai,M Ishii,Y Kurachi, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 122P-122P, 2004
  • Physiological actions of regulators of G-protein signaling (RGS) proteins, Masaru Ishii,Yoshihisa Kurachi, Life Sciences, Elsevier Inc., Vol. 74, No. 2-3, p. 163-171, 2003/12/05
  • Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina., Ishii M,Fujita A,Iwai K,Kusaka S,Higashi K,Inanobe A,Hibino H,Kurachi Y, 2003/07
  • Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders, Masaru Ishii,Norihiko Yamaguchi,Shiro Ohshima,Taeko Ishii,Kiyoshi L. Mori,Hiroshi Kimura,Tsuneo Morishima,Ichiro Kawase,Yukihiko Saeki, Internal Medicine, Japanese Society of Internal Medicine, Vol. 42, No. 3, p. 250-254, 2003/03/01
  • Characteristics of electromagnetic return-stroke models, Yoshihiro Baba,Masaru Ishii, IEEE Transactions on Electromagnetic Compatibility, Vol. 45, No. 1, p. 129-135, 2003/02
  • A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5, T Ishii,T Tatekawa,M Koseto,M Ishii,H Kobayashi,M Koike,T Fujii,Y Saeki, EUROPEAN JOURNAL OF HAEMATOLOGY, BLACKWELL MUNKSGAARD, Vol. 70, No. 2, p. 115-118, 2003/02
  • Cardiac conduction and arrhythmia: Insights from Nkx2.5 mutations in mouse and humans, Patrick Y. Jay,Charles I. Berul,Makoto Tanaka,Masao Ishii,Yoshihisa Kurachi,Seigo Izumo,Gourdie,Markwald,Thompson,Burch, Novartis Foundation Symposium, Vol. 250, p. 227-241, 2003
  • The 14-3-3 protein as a novel regulator of ion channel localisation, M Ishii,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 545, No. 1, p. 2-2, 2002/11
  • Idiopathic portal hypertension in a systemic sclerosis patient heterozygous for factor V Leiden mutation, Ishii M,Katada Y, 2002/11
  • PIPS inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel, M Ishii,A Inanobe,Y Kurachi, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 99, No. 7, p. 4325-4330, 2002/04
  • A mouse model of congenital heart disease: Cardiac arrhythmias and atrial septal defect caused by haploin sufficiency of the cardiac transcription factor Csx/Nkx2.5, M Tanaka,CI Berul,M Ishii,PY Jay,H Wakimoto,P Douglas,N Yamasaki,T Kawamoto,J Gehrmann,CT Maguire,M Schinke,CE Seidman,JG Seidman,Y Kurachi,S Izumo, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, Vol. 67, p. 317-325, 2002
  • A possible mechanism of NK cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) in a patient with chronic active Epstein-Barr virus infection (CAEBV) and severe hypersensitivity to mosquito bites (SHMB), Shiro Ohshima,Masaru Ishii,Hideo Asada,Toyoshi Tatekawa,Norihiko Yamaguchi,Hideyuki Kobayashi,Taeko Ishii,Toru Mima,Ichiro Kawase,Yukihiko Saeki, Internal Medicine, Japanese Society of Internal Medicine, Vol. 41, No. 8, p. 651-656, 2002
  • Ca2+ elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart, M Ishii,A Inanobe,S Fujita,YA Makino,Y Hosoya,Y Kurachi, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 89, No. 11, p. 1045-1050, 2001/11
  • Interaction between the RGS domain of RGS4 with G protein α subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel, A. Inanobe,S. Fujita,Y. Makino,K. Matsushita,M. Ishii,M. Chachin,Y. Kurachi, Journal of Physiology, Vol. 535, No. 1, p. 133-143, 2001/08/15
  • Possible association of "shrinking lung" and anti-Ro/SSA antibody, M Ishii,H Uda,T Yamagami,Y Katada, ARTHRITIS AND RHEUMATISM, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 11, p. 2612-2613, 2000/11
  • Characterization of lightning current measured on tall structures, Masaru Ishii,Yoshihiro Baba, SAE Technical Papers, 1999
  • Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90, Y Horio,H Hibino,A Inanobe,M Yamada,M Ishii,Y Tada,E Satoh,Y Hata,Y Takai,Y Kurachi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 20, p. 12885-12888, 1997/05
  • Expression and clustered distribution of an inwardly rectifying potassium channel, K(AB)-2/Kir4.1, on mammalian retinal Muller cell membrane: Their regulation by insulin and laminin signals, Masaru Ishii,Yoshiyuki Horio,Yoshihiko Tada,Hiroshi Hibino,Atsushi Inanobe,Minoru Ito,Mitsuhiko Yamada,Takahiro Gotow,Yasuo Uchiyama,Yoshihisa Kurachi, Journal of Neuroscience, Vol. 17, No. 20, p. 7725-7735, 1997

Misc.

  • 病理形態学の新技術・多光子励起顕微鏡を用いた病理診断, 松井崇浩,石井優, 病理と臨床, Vol. 37, No. 7, p. 609-616, 2019/07
  • The effects of biologic agents on osteoclast lineage cells evaluated by intravital two-photon microscopy, Yoshinobu Matsuura,Junichi Kikuta,Masaru Ishii, CYTOKINE, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 100, p. 111-112, 2017/12
  • Physical Cell-Cell Interaction Regulates Hepatic Glucose Metabolism in Mice, Kyoichiro Tsuchiya,Yasutaka Miyachi,Chikara Komiya,Kumiko Shiba,Noriko Shimazu,Shinobu Yamaguchi,Mizuko Osaka,Masayuki Yoshida,Koji Inoue,Kenjiro Wake,Yuta Sato,Junichi Kikuta,Masaru Ishii,Yoshihiro Ogawa, DIABETES, AMER DIABETES ASSOC, Vol. 65, p. A462-A462, 2016/06
  • Dynamic analysis of short-term effects of bisphosphonates by using intravital two-photon microscopy, Junichi Kikuta,Mai Shirazaki,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, Vol. 29, p. S193-S193, 2014/02
  • EBI2 guides osteoclast precursors to endosteal niches and regulates bone mass homeostasis., Erin Nevius,Mark Horowitz,Masaru Ishii,Joao Pereira, JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, Vol. 29, p. S45-S45, 2014/02
  • Development of an in vitro culture method for stepwise differentiation of mouse embryonic stem cells and induced pluripotent stem cells into mature osteoclasts, Keizo Nishikawa,Yoriko Iwamoto,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 116P-116P, 2014
  • イメージング技術の移植への応用 移植腎臓live imaging:functional MRIとmultiphoton microscopy 2つのmodality, 貝森 淳哉,市丸 直嗣,猪阪 善隆,楽木 宏実,石井 優,小林 英司,高原 史郎, 移植, (一社)日本移植学会, Vol. 48, No. 総会臨時, p. 239-239, 2013/08
  • Histamine attenuates acetylcholine-mediated sweating by inactivating GSK3 beta via H1-receptor mediated pathway, S. Matsui,H. Murota,Y. Lingli,K. Omiya,M. Ohmi,J. Kikuta,M. Ishii,I. Katayama, JOURNAL OF INVESTIGATIVE DERMATOLOGY, NATURE PUBLISHING GROUP, Vol. 133, p. S105-S105, 2013/05
  • Integrin alpha 9 on lymphatic endothelial cell at draining lymph node regulates lymphocyte egress via controlling S1P secretion during inflammation (P5114), Koyu Ito,Junko Morimoto,Akio Kihara,Szandor Simmons,Masaru Ishii,Toshimitsu Uede, JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 190, 2013/05
  • 消化器癌の生物学的動態を制御するエピジェネティクス, 太田勝也,原口直紹,賀川義規,加納義浩,今野雅允,植村守,西村潤一,竹政伊知朗,水島恒和,山本浩文,石井優,石井秀始,土岐祐一郎,森正樹, 日本外科学会雑誌, Vol. 114, 2013/03/05
  • YT-5-3(YRA) 消化器癌の生物学的動態を制御するエピジェネティクス(YT Young Researcher Award & Traveler's Grant,第113回日本外科学会定期学術集会), 太田 勝也,原口 直紹,賀川 義規,加納 義浩,今野 雅允,植村 守,西村 潤一,竹政 伊知朗,水島 恒和,山本 浩文,石井 優,石井 秀始,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, 2013/03/05
  • VF-022-2 生体イメージングによる細胞周期と浸潤関連分子の同定と臨床応用(VF ビデオフォーラム,第113回日本外科学会定期学術集会), 賀川 義規,前田 栄,深見 美和,菊田 順一,内藤 敦,西川 恵三,太田 勝也,藤森 さゆ美,Simmons Szandor,石井 泰子,植村 守,原口 直紹,西村 潤一,畑 泰司,竹政 伊知朗,水島 恒和,山本 浩文,石井 秀始,土岐 祐一郎,石井 優,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, 2013/03/05
  • YT-5-3(YRA) 消化器癌の生物学的動態を制御するエピジェネティクス(YT Young Researcher Award & Traveler's Grant,第113回日本外科学会定期学術集会), 太田 勝也,原口 直紹,賀川 義規,加納 義浩,今野 雅允,植村 守,西村 潤一,竹政 伊知朗,水島 恒和,山本 浩文,石井 優,石井 秀始,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, 2013/03/05
  • VF-022-2 生体イメージングによる細胞周期と浸潤関連分子の同定と臨床応用(VF ビデオフォーラム,第113回日本外科学会定期学術集会), 賀川 義規,前田 栄,深見 美和,菊田 順一,内藤 敦,西川 恵三,太田 勝也,藤森 さゆ美,Simmons Szandor,石井 泰子,植村 守,原口 直紹,西村 潤一,畑 泰司,竹政 伊知朗,水島 恒和,山本 浩文,石井 秀始,土岐 祐一郎,石井 優,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, 2013/03/05
  • S1P-mediated Osteoclast Precursor Monocyte Migration Is a Critical Point of Control in Antibone-resorptive Action of Active Vitamin D, Junichi Kikuta,Junichi Kikuta,Fumie Okiji,Mai Shirazaki,Sadaoki Sakai,Hitoshi Saito,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, Vol. 28, 2013/02
  • Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis, Masaru Ishii,Junichi Kikuta, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ELSEVIER SCIENCE BV, Vol. 1831, No. 1, p. 223-227, 2013/01
  • Dynamic in Vivo Imaging of Th17-Mediated Osteoclastic Bone Resorption in Live Bones by Using Intravital Multiphoton Microscopy, Junichi Kikuta,Masaru Ishii, ARTHRITIS AND RHEUMATISM, WILEY-BLACKWELL, Vol. 64, No. 10, p. S311-S312, 2012/10
  • 細胞周期制御の新展開 新規細胞周期依存性RhoGAP「Celmobilin」によるヒト癌細胞の遊走と浸潤の制御(New aspect of cell cycle research and cancer A novel cell cycle-associated RhoGAP, Celmobilin, regulates cancer cell motility and invasion in human), 賀川 義規,西川 恵三,前田 栄,松本 真司,奥崎 大介,三森 功士,山本 浩文,関本 貢嗣,菊池 章,石井 秀始,土岐 祐一郎,森 正樹,石井 優, 日本癌学会総会記事, 日本癌学会, Vol. 71回, p. 94-94, 2012/08
  • Migratory control of bone-resorbing osteoclasts visualized by intravital multiphoton microcopy, Masaru Ishii,Junichi Kikuta, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 23P-23P, 2012
  • Dynamic in vivo imaging of bone-resorptive functions of mature osteoclasts in live bones by using intravital multiphoton microscopy, Junichi Kikuta,Yoh Wada,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 70P-70P, 2012
  • 癌の生体イメージング―細胞周期と細胞可動性について―, 賀川義規,石井秀始,竹政伊知朗,水島恒和,池田正孝,山本浩文,関本貢嗣,土岐祐一郎,石井優,森正樹, 日本消化器外科学会雑誌(Web), Vol. 45, No. Supplement1, 2012
  • SF-035-4 二光子励起顕微鏡を用いたがん細胞の生体イメージング(SF-035 サージカルフォーラム(35)大腸:その他-1,第111回日本外科学会定期学術集会), 賀川 義規,石井 秀始,石井 泰子,久保 厚子,鈴木 陽三,宮崎 進,川村 俊輔,小谷 真奈斗,藤森 さゆ美,島津 裕,菊田 順一,竹政 伊知朗,水島 恒和,池田 正孝,山本 浩文,坂上-沢野 朝子,宮脇 敦史,石井 優,関本 貢嗣,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 112, No. 1, 2011/05/25
  • Chemokine-mediated migration control of bone cells visualized by intravital multiphoton bone imaging, Masaru Ishii,Junichi Kikuta,Atsuko Kubo,Yutaka Shimazu, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 57P-57P, 2011
  • Dynamic in vivo imaging of differentiation and function of osteoclasts in live bones by using intravital two-photon microscopy, Junichi Kikuta,Issei Nishiyama,Atsuko Kubo,Yutaka Shimazu,Yoh Wada,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 93P-93P, 2011
  • Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis (vol 458, pg 524, 2009), Masaru Ishii,Jackson G. Egen,Frederick Klauschen,Martin Meier-Schellersheim,Yukihiko Saeki,Jean Vacher,Richard L. Proia,Ronald N. Germain, NATURE, NATURE PUBLISHING GROUP, Vol. 465, No. 7300, 2010/06
  • Automated cell tracking and interaction analysis in intra-vital two-photon microscopy image data, Frederick Klauschen,Martin Meier-Schellersheim,Judith Mandl,Hai Qi,Masaru Ishii,Manfred Dietel,Ronald N. Germain,Carsten Denkert, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 70, 2010/04
  • Chemokine and lipid mediator-mediated control of osteoclast migration visualized by in vivo bone imaging: A novel point of regulation for bone homeostasis, Masaru Ishii, BONE, ELSEVIER SCIENCE INC, Vol. 46, p. S10-S11, 2010/03
  • Chemokine-mediated migration control of osteoclast precursors visualized by intravital bone imaging: A novel therapeutic target for bone diseases, Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 48P-48P, 2010
  • Osteoclast cell fusion: mechanisms and molecules, Masaru Ishii,Yukihiko Saeki, MODERN RHEUMATOLOGY, SPRINGER, Vol. 18, No. 3, p. 220-227, 2008/06
  • Osteoclast cell fusion: mechanisms and molecules, Masaru Ishii,Yukihiko Saeki, MODERN RHEUMATOLOGY, SPRINGER, Vol. 18, No. 3, p. 220-227, 2008/06
  • Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging, Ronald N. Germain,Marc Bajenoff,Flora Castellino,Marcello Chieppa,Jackson G. Egen,Alex Y. C. Huang,Masaru Ishii,Lily Y. Koo,Hai Qi, IMMUNOLOGICAL REVIEWS, WILEY, Vol. 221, p. 163-181, 2008/02
  • Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging, Ronald N. Germain,Marc Bajenoff,Flora Castellino,Marcello Chieppa,Jackson G. Egen,Alex Y. C. Huang,Masaru Ishii,Lily Y. Koo,Hai Qi, IMMUNOLOGICAL REVIEWS, WILEY, Vol. 221, p. 163-181, 2008/02
  • Abundant expression of tetraspanin CD9 in activated osteoclasts in ovariectomy-induced osteoporosis and in bone erosions of collagen-induced arthritis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, RHEUMATOLOGY INTERNATIONAL, SPRINGER HEIDELBERG, Vol. 28, No. 3, p. 225-231, 2008/01
  • Abundant expression of tetraspanin CD9 in activated osteoclasts in ovariectomy-induced osteoporosis and in bone erosions of collagen-induced arthritis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, RHEUMATOLOGY INTERNATIONAL, SPRINGER HEIDELBERG, Vol. 28, No. 3, p. 225-231, 2008/01
  • RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway, Kaori Iwai,Masato Koike,Shiro Ohshima,Kunio Miyatake,Yasuo Uchiyama,Yukihiko Saeki,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 22, No. 10, p. 1612-1620, 2007/10
  • Autoantibodies to cyclic citrullinated peptide 2 (CCP2) are superior to other potential diagnostic biomarkers for predicting rheumatoid arthritis in early undifferentiated arthritis, Eriko Kudo-Tanaka,Shiro Ohshima,Masaru Ishii,Toru Mima,Masato Matsushita,Naoto Azuma,Yoshinori Harada,Yoshinori Katada,Hitomi Ikeue,Mitsuko Umeshita-Sasai,Kunio Miyatake,Yukihiko Saeki, CLINICAL RHEUMATOLOGY, SPRINGER, Vol. 26, No. 10, p. 1627-1633, 2007/10
  • RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway, Kaori Iwai,Masato Koike,Shiro Ohshima,Kunio Miyatake,Yasuo Uchiyama,Yukihiko Saeki,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 22, No. 10, p. 1612-1620, 2007/10
  • Autoantibodies to cyclic citrullinated peptide 2 (CCP2) are superior to other potential diagnostic biomarkers for predicting rheumatoid arthritis in early undifferentiated arthritis, Eriko Kudo-Tanaka,Shiro Ohshima,Masaru Ishii,Toru Mima,Masato Matsushita,Naoto Azuma,Yoshinori Harada,Yoshinori Katada,Hitomi Ikeue,Mitsuko Umeshita-Sasai,Kunio Miyatake,Yukihiko Saeki, CLINICAL RHEUMATOLOGY, SPRINGER, Vol. 26, No. 10, p. 1627-1633, 2007/10
  • Visualization and identification of IL-7 producing cells, Scott K. Durum,Soren Warming,Scott M. Lawrence,Masaru Ishii,Mehrnoosh Abshari,Lionel Feigenbaum,A. Valance Washington,Andrew C. Warner,David J. Sims,Wen Qing Li,Julie A. Hixon,Daniel H. D. Gray,Benjamin E. Rich,Matthew Morrow,Miriam R. Anver,James Cherry,Dieter Naf,Lawrence R. Sternberg,Daniel W. MeVicar,Andrew G. Farr,Ronald N. Germain,Keith Rogers,Neal G. Copeland,Renata Mazzucchelli, CYTOKINE, ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, Vol. 39, No. 1, p. 9-10, 2007/07
  • Expression and function of transmembrane-4 superfamily (tetraspanin) proteins in osteoclasts: Reciprocal roles of Tspan-5 and NET-6 during osteoclastogenesis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, Allergology International, Japanese Society of Allergology, Vol. 56, No. 4, p. 457-463, 2007
  • A serological switching from anti-dsDNA to anti-Sm antibodies coincided with severe clinical manifestations of systemic lupus erythematosus (hemophagocytosis, profundus and psychosis), M. Ishii,Y. Muramoto,H. Kosaka,S. Ohshima,T. Mima,Y. Katada,S. Hirohata,Y. Saeki, LUPUS, SAGE PUBLICATIONS LTD, Vol. 16, No. 1, p. 67-69, 2007
  • Expression and function of transmembrane-4 superfamily (tetraspanin) proteins in osteoclasts: Reciprocal roles of Tspan-5 and NET-6 during osteoclastogenesis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, Allergology International, Japanese Society of Allergology, Vol. 56, No. 4, p. 457-463, 2007
  • A serological switching from anti-dsDNA to anti-Sm antibodies coincided with severe clinical manifestations of systemic lupus erythematosus (hemophagocytosis, profundus and psychosis), M. Ishii,Y. Muramoto,H. Kosaka,S. Ohshima,T. Mima,Y. Katada,S. Hirohata,Y. Saeki, LUPUS, SAGE PUBLICATIONS LTD, Vol. 16, No. 1, p. 67-69, 2007
  • Pigment pattern in jaguar/obelix zebrafish is caused by a Kir7.1 mutation: Implications for the regulation of melanosome movement, Motoko Iwashita,Masakatsu Watanabe,Masaru Ishii,Tim Chen,Stephen L. Johnson,Yoshihisa Kurachi,Norihiro Okada,Shigeru Kondo, PLOS GENETICS, PUBLIC LIBRARY SCIENCE, Vol. 2, No. 11, p. 1861-1870, 2006/11
  • Pigment pattern in jaguar/obelix zebrafish is caused by a Kir7.1 mutation: Implications for the regulation of melanosome movement, Motoko Iwashita,Masakatsu Watanabe,Masaru Ishii,Tim Chen,Stephen L. Johnson,Yoshihisa Kurachi,Norihiro Okada,Shigeru Kondo, PLOS GENETICS, PUBLIC LIBRARY SCIENCE, Vol. 2, No. 11, p. 1861-1870, 2006/11
  • Muscarinic acetylcholine receptors, Masaru Ishii,Yoshihisa Kurachi, Current Pharmaceutical Design, Vol. 12, No. 28, p. 3573-3581, 2006/10
  • RANKL-induced expression of tetraspanin CD9 is essential for cell fusion during osteoclastogenesis., Kaori Iwai,Masaru Ishii,Shiro Ohshima,Yukihiko Saeki, ARTHRITIS AND RHEUMATISM, WILEY-LISS, Vol. 54, No. 9, p. S531-S531, 2006/09
  • Spot pattern of leopard Danio is caused by mutation in the zebrafish connexin41.8 gene, Masakatsu Watanabe,Motoko Iwashita,Masaru Ishii,Yoshihisa Kurachi,Atsushi Kawakami,Shigeru Kondo,Norihiro Okada, EMBO REPORTS, NATURE PUBLISHING GROUP, Vol. 7, No. 9, p. 893-897, 2006/09
  • Spot pattern of leopard Danio is caused by mutation in the zebrafish connexin41.8 gene, Masakatsu Watanabe,Motoko Iwashita,Masaru Ishii,Yoshihisa Kurachi,Atsushi Kawakami,Shigeru Kondo,Norihiro Okada, EMBO REPORTS, NATURE PUBLISHING GROUP, Vol. 7, No. 9, p. 893-897, 2006/09
  • Minocycline-induced vasculitis fulfilling the criteria of polyarteritis nodosa, Yoshinori Katada,Yoshinori Harada,Naoto Azuma,Kengo Matsumoto,Haruko Terada,Eriko Kudo,Masaru Ishii,Hiroyuki Yamane,Suguru Yamamoto,Shiro Ohshima,Toru Mima,Toshio Tanaka,Yukihiko Saeki, Modern Rheumatology, Vol. 16, No. 4, p. 256-259, 2006/08
  • Minocycline-induced vasculitis fulfilling the criteria of polyarteritis nodosa, Yoshinori Katada,Yoshinori Harada,Naoto Azuma,Kengo Matsumoto,Haruko Terada,Eriko Kudo,Masaru Ishii,Hiroyuki Yamane,Suguru Yamamoto,Shiro Ohshima,Toru Mima,Toshio Tanaka,Yukihiko Saeki, Modern Rheumatology, Vol. 16, No. 4, p. 256-259, 2006/08
  • RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis, M Ishii,K Iwai,M Koike,S Ohshima,E Kudo-Tanaka,T Ishii,T Mima,Y Katada,K Miyatake,Y Uchiyama,Y Saeki, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 21, No. 6, p. 965-976, 2006/06
  • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis, N Takegahara,H Takamatsu,T Toyofuku,T Tsujimura,T Okuno,K Yukawa,M Mizui,M Yamamoto,DVR Prasad,K Suzuki,M Ishii,K Terai,M Moriya,Y Nakatsuji,S Sakoda,S Sato,S Akira,K Takeda,M Inui,T Takai,M Ikawa,M Okabe,A Kumanogoh,H Kikutani, NATURE CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 8, No. 6, p. 615-622, 2006/06
  • RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis, M Ishii,K Iwai,M Koike,S Ohshima,E Kudo-Tanaka,T Ishii,T Mima,Y Katada,K Miyatake,Y Uchiyama,Y Saeki, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 21, No. 6, p. 965-976, 2006/06
  • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis, N Takegahara,H Takamatsu,T Toyofuku,T Tsujimura,T Okuno,K Yukawa,M Mizui,M Yamamoto,DVR Prasad,K Suzuki,M Ishii,K Terai,M Moriya,Y Nakatsuji,S Sakoda,S Sato,S Akira,K Takeda,M Inui,T Takai,M Ikawa,M Okabe,A Kumanogoh,H Kikutani, NATURE CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 8, No. 6, p. 615-622, 2006/06
  • RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis, Masaru Ishii,Yukihiko Saeki, JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 176, p. S193-S193, 2006/04
  • Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins, RA Roof,YF Jin,DL Roman,RK Sunahara,M Ishii,HI Mosberg,RR Neubig, CHEMICAL BIOLOGY & DRUG DESIGN, BLACKWELL PUBLISHING, Vol. 67, No. 4, p. 266-274, 2006/04
  • Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins, RA Roof,YF Jin,DL Roman,RK Sunahara,M Ishii,HI Mosberg,RR Neubig, CHEMICAL BIOLOGY & DRUG DESIGN, BLACKWELL PUBLISHING, Vol. 67, No. 4, p. 266-274, 2006/04
  • Muscarinic acetylcholine receptors., Ishii M,Kurachi Y, Current Pharmaceutical Design, Vol. 12, p. 3573-3581, 2006
  • Carvedilol blocks cardiac K-ATP and K-G but not I-K1 channels by acting at the bundle-crossing regions, J Kikuta,M Ishii,K Kishimoto,Y Kurachi, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 529, No. 1-3, p. 47-54, 2006/01
  • Carvedilol blocks cardiac K-ATP and K-G but not I-K1 channels by acting at the bundle-crossing regions, J Kikuta,M Ishii,K Kishimoto,Y Kurachi, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 529, No. 1-3, p. 47-54, 2006/01
  • In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: Possible involvement of lipid raft, M Ishii,M Ikushima,Y Kurachi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 338, No. 2, p. 839-846, 2005/12
  • In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: Possible involvement of lipid raft, M Ishii,M Ikushima,Y Kurachi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 338, No. 2, p. 839-846, 2005/12
  • Phosphatidylinositol 3,4,5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action, M Ishii,S Fujita,M Yamada,Y Hosaka,Y Kurachi, BIOCHEMICAL JOURNAL, PORTLAND PRESS, Vol. 385, No. 1, p. 65-73, 2005/01
  • Chronic active EBV infection and Hypersensitivity to Mosquito Bites: Pathophysiology and Pharmacology., Ishii M,Ohshima S,Saeki Y, Current Rheumatology Reviews, Vol. 1, p. 65-70, 2005
  • Phosphatidylinositol 3,4,5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action, M Ishii,S Fujita,M Yamada,Y Hosaka,Y Kurachi, BIOCHEMICAL JOURNAL, PORTLAND PRESS, Vol. 385, No. 1, p. 65-73, 2005/01
  • Chronic active EBV infection and Hypersensitivity to Mosquito Bites: Pathophysiology and Pharmacology., Ishii M,Ohshima S,Saeki Y, Current Rheumatology Reviews, Vol. 1, p. 65-70, 2005
  • Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: Implication for dimerization of nucleotide-binding domains to induce channel opening, M Yamada,M Ishii,H Hibino,Y Kurachi, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 66, No. 4, p. 807-816, 2004/10
  • Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: Implication for dimerization of nucleotide-binding domains to induce channel opening, M Yamada,M Ishii,H Hibino,Y Kurachi, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 66, No. 4, p. 807-816, 2004/10
  • Assays of RGS protein modulation by phosphatidylinositides and calmodulin, Masaru Ishii,Yoshihisa Kurachi, Methods in Enzymology, Vol. 389, p. 105-118, 2004
  • Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential, H Hibino,K Higashi-Shingai,A Fujita,K Iwai,M Ishii,Y Kurachi, EUROPEAN JOURNAL OF NEUROSCIENCE, WILEY-BLACKWELL, Vol. 19, No. 1, p. 76-84, 2004/01
  • Cell signal control of the G protein-gated potassium channel and its subcellular localization., Kurachi Y,Ishii M, The Journal of Physiology, Vol. 554, No. 2, p. 285-294, 2004
  • Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential, H Hibino,K Higashi-Shingai,A Fujita,K Iwai,M Ishii,Y Kurachi, EUROPEAN JOURNAL OF NEUROSCIENCE, WILEY-BLACKWELL, Vol. 19, No. 1, p. 76-84, 2004/01
  • Assay of RGS protein modulation by phosphatidylinositides and calmodulin., Ishii M,Kurachi Y, Methods in Enzymology, Vol. 389, p. 105-118, 2004
  • Physiological actions of regulators of G-protein signaling (RGS) proteins, M Ishii,Y Kurachi, LIFE SCIENCES, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 74, No. 2-3, p. 163-171, 2003/12
  • Physiological actions of regulators of G-protein signaling (RGS) proteins, M Ishii,Y Kurachi, LIFE SCIENCES, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 74, No. 2-3, p. 163-171, 2003/12
  • Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina, M Ishii,A Fujita,K Iwai,S Kusaka,K Higashi,A Inanobe,H Hibino,Y Kurachi, AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 285, No. 2, p. C260-C267, 2003/08
  • Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina, M Ishii,A Fujita,K Iwai,S Kusaka,K Higashi,A Inanobe,H Hibino,Y Kurachi, AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 285, No. 2, p. C260-C267, 2003/08
  • Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders, M Ishii,N Yamaguchi,S Ohshima,T Ishii,KL Mori,H Kimura,T Morishima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 42, No. 3, p. 250-254, 2003/03
  • Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders, M Ishii,N Yamaguchi,S Ohshima,T Ishii,KL Mori,H Kimura,T Morishima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 42, No. 3, p. 250-254, 2003/03
  • A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5, T Ishii,T Tatekawa,M Koseto,M Ishii,H Kobayashi,M Koike,T Fujii,Y Saeki, EUROPEAN JOURNAL OF HAEMATOLOGY, BLACKWELL MUNKSGAARD, Vol. 70, No. 2, p. 115-118, 2003/02
  • A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5, T Ishii,T Tatekawa,M Koseto,M Ishii,H Kobayashi,M Koike,T Fujii,Y Saeki, EUROPEAN JOURNAL OF HAEMATOLOGY, BLACKWELL MUNKSGAARD, Vol. 70, No. 2, p. 115-118, 2003/02
  • Idiopathic portal hypertension in a systemic sclerosis patient heterozygous for factor V Leiden mutation, M Ishii,Y Katada, RHEUMATOLOGY INTERNATIONAL, SPRINGER-VERLAG, Vol. 23, No. 1, p. 44-46, 2003/01
  • Cardiac conduction and arrhythmia: Insights from Nkx2.5 mutations in mouse and humans, Patrick Y. Jay,Charles I. Berul,Makoto Tanaka,Masao Ishii,Yoshihisa Kurachi,Seigo Izumo,Gourdie,Markwald,Thompson,Burch, Novartis Foundation Symposium, Vol. 250, p. 227-241, 2003
  • Idiopathic portal hypertension in a systemic sclerosis patient heterozygous for factor V Leiden mutation, M Ishii,Y Katada, RHEUMATOLOGY INTERNATIONAL, SPRINGER-VERLAG, Vol. 23, No. 1, p. 44-46, 2003/01
  • Cell signal control of the G protein-gated potassium channel and its subcellular localization., Kurachi Y,Ishii M, The Journal of Physiology, Vol. 554, No. 2, p. 285-294, 2003
  • Cardiac conduction and arrhythmia: Insights from Nkx2.5 mutations in mouse and humans, Patrick Y. Jay,Charles I. Berul,Makoto Tanaka,Masao Ishii,Yoshihisa Kurachi,Seigo Izumo,Gourdie,Markwald,Thompson,Burch, Novartis Foundation Symposium, Vol. 250, p. 227-241, 2003
  • The 14-3-3 protein as a novel regulator of ion channel localisation, M Ishii,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 545, No. 1, p. 2-2, 2002/11
  • A possible mechanism of NK cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) in a patient with chronic active Epstein-Barr virus infection (CAEBV) and severe hypersensitivity to mosquito bites (SHMB), S Ohshima,M Ishii,H Asada,T Tatekawa,N Yamaguchi,H Kobayashi,T Ishii,T Mima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 41, No. 8, p. 651-656, 2002/08
  • A possible mechanism of NK cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) in a patient with chronic active Epstein-Barr virus infection (CAEBV) and severe hypersensitivity to mosquito bites (SHMB), S Ohshima,M Ishii,H Asada,T Tatekawa,N Yamaguchi,H Kobayashi,T Ishii,T Mima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 41, No. 8, p. 651-656, 2002/08
  • PIP3 inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel, Masaru Ishii,Atsushi Inanobe,Yoshihisa Kurachi, Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 7, p. 4325-4330, 2002/04/02
  • PIPS inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel, M Ishii,A Inanobe,Y Kurachi, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 99, No. 7, p. 4325-4330, 2002/04
  • The 14-3-3 protein as a novel regulator of ion channel localisation., Ishii M,Kurachi Y, The Journal of Physiology, Vol. 545, No. 1, 2002
  • A mouse model of congenital heart disease: Cardiac arrhythmias and atrial septal defect caused by haploin sufficiency of the cardiac transcription factor Csx/Nkx2.5, M Tanaka,CI Berul,M Ishii,PY Jay,H Wakimoto,P Douglas,N Yamasaki,T Kawamoto,J Gehrmann,CT Maguire,M Schinke,CE Seidman,JG Seidman,Y Kurachi,S Izumo, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, Vol. 67, p. 317-325, 2002
  • A mouse model of congenital heart disease: Cardiac arrhythmias and atrial septal defect caused by haploin sufficiency of the cardiac transcription factor Csx/Nkx2.5, M Tanaka,CI Berul,M Ishii,PY Jay,H Wakimoto,P Douglas,N Yamasaki,T Kawamoto,J Gehrmann,CT Maguire,M Schinke,CE Seidman,JG Seidman,Y Kurachi,S Izumo, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, Vol. 67, p. 317-325, 2002
  • Ca2+ elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart, M Ishii,A Inanobe,S Fujita,YA Makino,Y Hosoya,Y Kurachi, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 89, No. 11, p. 1045-1050, 2001/11
  • Ca2+ elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart, M Ishii,A Inanobe,S Fujita,YA Makino,Y Hosoya,Y Kurachi, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 89, No. 11, p. 1045-1050, 2001/11
  • Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel, A Inanobe,S Fujita,Y Makino,K Matsushita,M Ishii,M Chachin,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 535, No. 1, p. 133-143, 2001/08
  • Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel, A Inanobe,S Fujita,Y Makino,K Matsushita,M Ishii,M Chachin,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 535, No. 1, p. 133-143, 2001/08
  • Possible association of "shrinking lung" and anti-Ro/SSA antibody, M Ishii,H Uda,T Yamagami,Y Katada, ARTHRITIS AND RHEUMATISM, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 11, p. 2612-2613, 2000/11
  • Possible association of "shrinking lung" and anti-Ro/SSA antibody, M Ishii,H Uda,T Yamagami,Y Katada, ARTHRITIS AND RHEUMATISM, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 11, p. 2612-2613, 2000/11
  • Expression and clustered distribution of an inwardly rectifying potassium channel, K-AB-2/Kir4.1, on mammalian retinal Muller cell membrane: Their regulation by insulin and laminin signals, M Ishii,Y Horio,Y Tada,H Hibino,A Inanobe,M Ito,M Yamada,T Gotow,Y Uchiyama,Y Kurachi, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 17, No. 20, p. 7725-7735, 1997/10
  • Expression and clustered distribution of an inwardly rectifying potassium channel, K-AB-2/Kir4.1, on mammalian retinal Muller cell membrane: Their regulation by insulin and laminin signals, M Ishii,Y Horio,Y Tada,H Hibino,A Inanobe,M Ito,M Yamada,T Gotow,Y Uchiyama,Y Kurachi, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 17, No. 20, p. 7725-7735, 1997/10
  • Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90, Y Horio,H Hibino,A Inanobe,M Yamada,M Ishii,Y Tada,E Satoh,Y Hata,Y Takai,Y Kurachi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 20, p. 12885-12888, 1997/05
  • Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90, Y Horio,H Hibino,A Inanobe,M Yamada,M Ishii,Y Tada,E Satoh,Y Hata,Y Takai,Y Kurachi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 20, p. 12885-12888, 1997/05

Publications

  • G protein and effectors., Encyclopedia of Endocrine Diseases. Academic Press, 2004

Works

  • G蛋白質制御蛋白質(RGS蛋白質)の阻害剤の開発と活性測定(米国ミシガン大学との国際共同研究), 2005 -

Awards

  • 第11回・日本学術振興会賞, 石井 優, 日本学術振興会, 2014/12
  • 平成25年度日本医師会・医学研究奨励賞, 石井 優, 日本医師会, 2013/11
  • 学術賞, 石井 優, 日本骨代謝学会, 2013/05
  • 若手研究者表彰事業・会長賞, 石井 優, 長寿科学振興財団, 2011/12
  • 第41回・最優秀理事長賞, 石井 優, 病態代謝研究会, 2010/11
  • 科学技術分野の文部科学大臣表彰・若手科学者賞, 石井 優, 文部科学省, 2010/04
  • Young Investigator’s Award, The Japanese College of Rheumatology, 2007
  • 日本リウマチ学会・学会奨励賞, 2007
  • Young Investigator's Award, The Japanse Society of Allergology, 2006
  • 第2回・日本アレルギー学会学術大会賞, 2006
  • 31st International Congress of Electrocardiology, Young Investigator’s Award, 1st Prize, 2005
  • Young Investigator’s Award, 1st Prize, 31st International Congress of Electrocardiology, 2004
  • Best Presentation Award, The Japanese Pharmacological Society, 2004
  • 第77回日本薬理学会年会・優秀発表賞, 2004
  • Best Presentation Award, The Japanese Pharmacological Society, 2003
  • 第76回日本薬理学会年会・優秀発表賞, 2003
  • Young Investigator Award, The Japanese Society of Electrocardiology, 2002
  • Young Investigator Award, The 2nd Annual ASPET G protein-coupled receptor symposium., 2002
  • The 2nd Annual ASPET G protein-coupled receptor symposium Young Investigator Award, 2002
  • 日本心電学会学術奨励賞最優秀賞, 2002
  • 第10回日本心臓財団・入澤宏記念研究奨励賞, 2001

Committee Memberships

  • 日本骨代謝学会, 理事, 2017/07 - Present
  • : 日本臨床免疫学会 評議員, 2016 - Present
  • : 日本炎症・再生医学会 常務理事(学術担当), 2016 - Present
  • 日本臨床免疫学会, 評議員, 2016 - Present
  • 日本炎症・再生医学会, 常務理事(学術担当), 2016 - Present
  • : 日本骨免疫学会 理事, 2015 - Present
  • : 日本免疫学会 評議員, 2015 - Present
  • 日本骨免疫学会, 理事, 2015 - Present
  • 日本免疫学会, 評議員, 2015 - Present
  • : 日本炎症・再生医学会 評議員, 2014 - Present
  • 日本炎症・再生医学会, 評議員, 2014 - Present
  • : 日本骨代謝学会 評議員, 2013 - Present
  • 日本骨代謝学会, 評議員, 2013 - Present
  • : 日本リウマチ学会 評議員, 2012 - Present
  • 日本リウマチ学会, 評議員, 2012 - Present
  • : 日本薬理学会 学術評議員, 2006 - Present
  • 日本薬理学会, 学術評議員, 2006 - Present
  • : 日本アレルギー学会 専門医, 2006 - 2011
  • 日本アレルギー学会, 専門医, 2006 - 2011
  • -: Japanese Society of Pharmacology Boardman, 2006 -
  • -: Japanese Society of Allergology Specialist, 2006 -
  • Japanese Society of Pharmacology, Boardman, 2006 -
  • Japanese Society of Allergology, Specialist, 2006 -