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Ishii Masaru

石井　優

Graduate School of Frontier Biosciences　Department of Frontier Biosciences, Professor

keyword pharmacology，in vivo imaging，immunology，osteobiology

Education

  • - 1998, Osaka University, Faculty of Medicine
  • - 1998, Osaka University, Faculty of Medicine, Medical School

Research History

  • 2018/10 - Present, National Institutes of Biomedical Innovation, Health and Nutrition
  • 2013/04 - Present, Osaka University, Graduate School of Medicine
  • 2011/04 - 2013/03, Osaka University, WPI Immunology Frontier Research Center
  • 2009/04 - 2011/03, Osaka University, WPI Immunology Frontier Research Center
  • 2005/07 - 2009/03, National Hospital Organization
  • 2006/06 - 2008/05, Human Frontier Science Program Long-term Fellow
  • 2006/06 - 2008/05, National Institute of Allergy and Infectious Diseases, National Institutes of Health (Maryland/USA), Visiting Researcher
  • 2000 - 2005, 大阪大学医学系研究科, 助手

Research Areas

  • Life sciences, Allergies and connective tissue disease
  • Life sciences, Internal medicine - General
  • Life sciences, Immunology
  • Life sciences, Medical biochemistry
  • Life sciences, Pharmacology
  • Life sciences, Clinical pharmacy
  • Life sciences, Physiology

Professional Memberships

  • Japanese College of Rheumatology
  • Japanese Society of Physiology
  • Japanese Society of Pharmacology
  • Japanese Society of Allergology
  • Japanese Society of Internal Medicine
  • Japanese Society of Biochemistry
  • Biophysical Society
  • 日本リウマチ学会
  • Biophysical Society
  • 日本アレルギー学会
  • 日本内科学会
  • 日本生化学会
  • 日本薬理学会

Papers

  • 特集 新組織学シリーズⅣ:骨･軟骨 Ⅰ.骨･軟骨組織の構造と細胞分化･機能 骨組織の生体イメージング, 鎗 伸弥,菊田 順一,石井 優, 生体の科学, 株式会社医学書院, Vol. 74, No. 6, p. 540-543, 2023/12/15
  • Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis, Nobutaka Takeda,Atsunori Tsuchiya,Masaki Mito,Kazuki Natsui,Yui Natusi,Yohei Koseki,Kei Tomiyoshi,Fusako Yamazaki,Yuki Yoshida,Hiroyuki Abe,Masayuki Sano,Taketomo Kido,Yusuke Yoshioka,Junichi Kikuta,Tohru Itoh,Ken Nishimura,Masaru Ishii,Takahiro Ochiya,Atsushi Miyajima,Shuji Terai, Inflammation and Regeneration, Vol. 43, No. 1, p. 48-48, 2023/10
  • Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow., Shinya Abe,Takuma Asahi,Takahiro Hara,Guangwei Cui,Akihiro Shimba,Shizue Tani-Ichi,Kohei Yamada,Kazuko Miyazaki,Hitoshi Miyachi,Satsuki Kitano,Naotoshi Nakamura,Junichi Kikuta,Alexis Vandenbon,Masaki Miyazaki,Ryo Yamada,Toshiaki Ohteki,Masaru Ishii,Veronika Sexl,Takashi Nagasawa,Koichi Ikuta, Cell reports, p. 113127-113127, 2023/09/10
  • Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction, Kotaro Shimizu,Junichi Kikuta,Yumi Ohta,Yutaka Uchida,Yu Miyamoto,Akito Morimoto,Shinya Yari,Takashi Sato,Takefumi Kamakura,Kazuo Oshima,Ryusuke Imai,Yu-Chen Liu,Daisuke Okuzaki,Tetsuya Hara,Daisuke Motooka,Noriaki Emoto,Hidenori Inohara,Masaru Ishii, Nature Communications, Springer Science and Business Media LLC, Vol. 14, No. 1, 2023/08/03
  • 骨組織pHを測定するレシオ蛍光イメージングプローブの開発, 三木 初音,吉村 康孝,蓑島 維文,鎗 伸弥,菊田 順一,石井 優,菊地 和也, JSMI Report, 日本分子イメージング学会, Vol. 16, No. 2, p. 110-110, 2023/05
  • 光-電子相関顕微鏡法とFocused Ion Beam Scanning Electron Microscopeを用いた破骨細胞の三次元構造解析, 細沼雅弘,細沼雅弘,坂井信裕,坂井信裕,坂井信裕,松島英輝,松島英輝,松島英輝,菊田順一,高木孝士,武部明,石井優,高見正道,高見正道, 日本骨形態計測学会雑誌, 日本骨形態計測学会, Vol. 33, No. 1, p. 198-198, 2023/05
  • 骨組織pHを測定するレシオ蛍光イメージングプローブの開発, 三木 初音,吉村 康孝,蓑島 維文,鎗 伸弥,菊田 順一,石井 優,菊地 和也, JSMI Report, 日本分子イメージング学会, Vol. 16, No. 2, p. 110-110, 2023/05
  • A Cell Tracking Method for Dynamic Analysis of Immune Cells Based on Deep Learning, Aya Watanabe,Kenji Fujimoto,Hironori Shigeta,Shigeto Seno,Yutaka Uchida,Masaru Ishii,Hideo Matsuda, International Journal of Machine Learning, EJournal Publishing, Vol. 13, No. 2, p. 64-69, 2023/04
  • JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors., Shinya Yari,Junichi Kikuta,Hotaka Shigyo,Yu Miyamoto,Daisuke Okuzaki,Yuki Furusawa,Masafumi Minoshima,Kazuya Kikuchi,Masaru Ishii, Inflammation and regeneration, Vol. 43, No. 1, p. 18-18, 2023/03/03
  • 生体イメージングによる炎症性破骨細胞の動態・機能解析, 菊田 順一,石井 優, 日本リウマチ学会総会・学術集会プログラム・抄録集, (一社)日本リウマチ学会, Vol. 67回, p. 766-766, 2023/03
  • Progressive differentiation toward the long-lived plasma cell compartment in the bone marrow, Takuya Koike,Kentaro Fujii,Kohei Kometani,Noah S. Butler,Kenji Funakoshi,Shinya Yari,Junichi Kikuta,Masaru Ishii,Tomohiro Kurosaki,Wataru Ise, Journal of Experimental Medicine, Rockefeller University Press, Vol. 220, No. 2, 2023/02/06
  • In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma, Seiji Taniguchi,Takahiro Matsui,Kenji Kimura,Soichiro Funaki,Yu Miyamoto,Yutaka Uchida,Takao Sudo,Junichi Kikuta,Tetsuya Hara,Daisuke Motooka,Yu-Chen Liu,Daisuke Okuzaki,Eiichi Morii,Noriaki Emoto,Yasushi Shintani,Masaru Ishii, Nature Communications, Springer Science and Business Media LLC, Vol. 14, No. 1, 2023/01/17
  • 【最新の骨粗鬆症学(第2版)-骨粗鬆症学の最新知見-】骨研究フロンティア 骨の構造と機能 骨組織の動態機構とその制御, 上中 麻希,菊田 順一,石井 優, 日本臨床, (株)日本臨床社, Vol. 81, No. 増刊1 最新の骨粗鬆症学, p. 64-70, 2023/01
  • 臨床免疫領域における画像・組織による診断・病型分類の役割 生体多光子励起イメージングによる免疫疾患の病態解明, 菊田 順一,石井 優, 日本臨床免疫学会総会プログラム・抄録集, (一社)日本臨床免疫学会, Vol. 50回, p. 60-60, 2022/10
  • 【シングルセル解析による免疫細胞研究の新展開】生体イメージングとオミックス解析の統合による炎症性病態の真相解明, 宮本 佑,菊田 順一,石井 優, 炎症と免疫, (株)先端医学社, Vol. 30, No. 6, p. 495-500, 2022/10
  • Vocabulary 生体多光子励起イメージング, 鎗 伸弥,菊田 順一,石井 優, 整形外科, (株)南江堂, Vol. 73, No. 11, p. 1168-1168, 2022/10
  • 【自己免疫疾患 層別化する新時代へ 臨床検体のマルチオミクス解析、腸内細菌によって見えてきた免疫経路の全容】(第3章)自己免疫疾患の特異的病態経路の解明 生体イメージングが照らし出す臓器炎症プロセスの実態, 宮本 佑,菊田 順一,石井 優, 実験医学, (株)羊土社, Vol. 40, No. 15, p. 2539-2545, 2022/09
  • Label‐free multiphoton excitation imaging as a promising diagnostic tool for breast cancer, Takahiro Matsui,Akio Iwasa,Masafumi Mimura,Seiji Taniguchi,Takao Sudo,Yutaka Uchida,Junichi Kikuta,Hidetomo Morizono,Rie Horii,Yuichi Motoyama,Eiichi Morii,Shinji Ohno,Yasujiro Kiyota,Masaru Ishii, Cancer Science, Wiley, Vol. 113, No. 8, p. 2916-2925, 2022/08
  • 【基盤病態としての慢性炎症】慢性炎症の生体イメージング, 揚村 朋弥,菊田 順一,石井 優, 医学のあゆみ, 医歯薬出版(株), Vol. 282, No. 1, p. 105-111, 2022/07
  • Rising Stars in Skeletal Biology 骨芽細胞由来の細胞外小胞は骨形成期から骨吸収期への相転換に関与する, 上中 麻希,菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 40回, p. 94-94, 2022/07
  • 二光子イメージングを用いた細胞外ATP依存的なCD137アゴニスト抗体による全身免疫活性化低減の検証, 金子 知里,筒井 遥香,尾関 和久,本多 正樹,原谷 健太,成田 義規,櫻井 実香,菊田 順一,田保 充康,石井 優, The Journal of Toxicological Sciences, (一社)日本毒性学会, Vol. 47, No. Suppl., p. S110-S110, 2022/06
  • 骨ミネラル代謝の新知見 SLPI PTH誘導性骨形成における新規メディエーターの発見, 石井 優,菊田 順一, 日本腎臓学会誌, (一社)日本腎臓学会, Vol. 64, No. 3, p. 209-209, 2022/05
  • 【最新関節リウマチ学(第2版)-寛解・治癒を目指した研究と最新治療-】関節リウマチの臓器障害と合併症・薬剤副作用対策 骨粗鬆症、骨折(薬剤性を含む), 塚崎 裕之,菊田 順一,石井 優, 日本臨床, (株)日本臨床社, Vol. 80, No. 増刊4 最新関節リウマチ学, p. 625-629, 2022/04
  • Determination of the physiological range of oxygen tension in bone marrow monocytes using two-photon phosphorescence lifetime imaging microscopy., Ayako Narazaki,Reito Shimizu,Toshitada Yoshihara,Junichi Kikuta,Reiko Sakaguchi,Seiji Tobita,Yasuo Mori,Masaru Ishii,Keizo Nishikawa, Scientific reports, Vol. 12, No. 1, p. 3497-3497, 2022/03/10
  • 【シン・マクロファージ あらゆる疾患を制御する機能的多様性】(第2章)病気とマクロファージの多様性を知る14の方法 関節破壊を惹起する炎症性マクロファージの同定 破骨前駆細胞の新たなサブセット, 揚村 朋弥,長谷川 哲雄,菊田 順一,石井 優, 実験医学, (株)羊土社, Vol. 40, No. 5, p. 697-703, 2022/03
  • Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo., Maki Uenaka,Erika Yamashita,Junichi Kikuta,Akito Morimoto,Tomoka Ao,Hiroki Mizuno,Masayuki Furuya,Tetsuo Hasegawa,Hiroyuki Tsukazaki,Takao Sudo,Keizo Nishikawa,Daisuke Okuzaki,Daisuke Motooka,Nobuyoshi Kosaka,Fuminori Sugihara,Thomas Boettger,Thomas Braun,Takahiro Ochiya,Masaru Ishii, Nature communications, Vol. 13, No. 1, p. 1066-1066, 2022/02/24
  • Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis., Gota Yoshida,Tsuyoshi Kawabata,Hyota Takamatsu,Shotaro Saita,Shuhei Nakamura,Keizo Nishikawa,Mari Fujiwara,Yusuke Enokidani,Tadashi Yamamuro,Keisuke Tabata,Maho Hamasaki,Masaru Ishii,Atsushi Kumanogoh,Tamotsu Yoshimori, Autophagy, p. 1-10, 2022/01/13
  • 【夜明けを迎えたヒト免疫学 臨床検体からヒトの免疫応答機構の実態を知り、疾患制御に挑む】生体ライブイメージング技術から展開する新たなヒト免疫学, 宮本 佑,菊田 順一,石井 優, 実験医学, (株)羊土社, Vol. 40, No. 1, p. 47-53, 2022/01
  • The Effects of Vitamin D on Immune System and Inflammatory Diseases., Tomoka Ao,Junichi Kikuta,Masaru Ishii, Biomolecules, Vol. 11, No. 11, 2021/11/03
  • Anti-Siglec-15 antibody suppresses bone resorption by inhibiting osteoclast multinucleation without attenuating bone formation., Hiroyuki Tsukazaki,Junichi Kikuta,Tomoka Ao,Akito Morimoto,Chie Fukuda,Eisuke Tsuda,Masafumi Minoshima,Kazuya Kikuchi,Takashi Kaito,Masaru Ishii, Bone, Vol. 152, p. 116095-116095, 2021/11
  • Osteoclasts adapt to physioxia perturbation through DNA demethylation., Keizo Nishikawa,Shigeto Seno,Toshitada Yoshihara,Ayako Narazaki,Yuki Sugiura,Reito Shimizu,Junichi Kikuta,Reiko Sakaguchi,Norio Suzuki,Norihiko Takeda,Hiroaki Semba,Masamichi Yamamoto,Daisuke Okuzaki,Daisuke Motooka,Yasuhiro Kobayashi,Makoto Suematsu,Haruhiko Koseki,Hideo Matsuda,Masayuki Yamamoto,Seiji Tobita,Yasuo Mori,Masaru Ishii, EMBO reports, Vol. 22, No. 12, 2021/10/18
  • 見る脂質のページ イメージングと細胞解析でみるイムノメタボリズム(第2回) In vivoライブイメージング技術を活用したイムノメタボリズムの見える化, 宮本 佑,菊田 順一,石井 優, The Lipid, (株)メディカルレビュー社, Vol. 32, No. 2, p. 106-113, 2021/10
  • 生体イメージングの進歩と新たな技術開発への挑戦, 粟生 智香,菊田 順一,石井 優, ファルマシア, (公社)日本薬学会, Vol. 57, No. 10, p. 917-921, 2021/10
  • 最新のテクノロジーが切り拓く骨代謝研究 生体イメージングと骨代謝, 菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 39回, p. 89-89, 2021/10
  • Rising Stars in Skeletal Biology SLPIはPTH誘導性骨形成に重要なメディエーターである, 森本 彬人,菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 39回, p. 105-105, 2021/10
  • 【脳とからだ】腸,免疫系,脳の相互作用 交感神経系による骨髄の制御, 粟生 智香,菊田 順一,石井 優, 生体の科学, (公財)金原一郎記念医学医療振興財団, Vol. 72, No. 5, p. 393-396, 2021/10
  • 関節炎の炎症性骨破壊に関与する悪玉破骨前駆細胞の同定と機能, 揚村 朋弥,長谷川 哲雄,菊田 順一,石井 優, 感染・炎症・免疫, 鳥居薬品(株), Vol. 51, No. 2, p. 89-99, 2021/10
  • Group 2 innate lymphoid cells in bone marrow regulate osteoclastogenesis in a reciprocal manner via RANKL, GM-CSF and IL-13., Yoshiki Momiuchi,Yasutaka Motomura,Emiko Suga,Hiroki Mizuno,Junichi Kikuta,Akito Morimoto,Miho Mochizuki,Natsuko Otaki,Masaru Ishii,Kazuyo Moro, International immunology, Vol. 33, No. 11, p. 573-585, 2021/09/09
  • 【関節リウマチの診療update-最新の診断と治療-】関節リウマチの病態と治療薬の作用点, 鎗 伸弥,菊田 順一,石井 優, 日本臨床, (株)日本臨床社, Vol. 79, No. 9, p. 1272-1276, 2021/09
  • A CNN-based cell tracking method for multi-slice intravital imaging data, Kenji Fujimoto,Tsubasa Mizugaki,Utkrisht Rajkumar,Hironori Shigeta,Shigeto Seno,Yutaka Uchida,Masaru Ishii,Vineet Bafna,Hideo Matsuda, Proceedings of the 12th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics, ACM, 2021/08
  • 骨のライブイメージング, 鎗 伸弥,菊田 順一,石井 優, 細胞, (株)ニュー・サイエンス社, Vol. 53, No. 7, p. 420-421, 2021/06
  • Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation., Tomoaki Koga,Fumiyuki Sasaki,Kazuko Saeki,Soken Tsuchiya,Toshiaki Okuno,Mai Ohba,Takako Ichiki,Satoshi Iwamoto,Hirotsugu Uzawa,Keiko Kitajima,Chikara Meno,Eri Nakamura,Norihiro Tada,Yoshinori Fukui,Junichi Kikuta,Masaru Ishii,Yukihiko Sugimoto,Mitsuyoshi Nakao,Takehiko Yokomizo, Cellular & molecular immunology, Vol. 18, No. 6, p. 1437-1449, 2021/06
  • Group 2 innate lymphoid cells support hematopoietic recovery under stress conditions, Takao Sudo,Yasutaka Motomura,Daisuke Okuzaki,Tetsuo Hasegawa,Takafumi Yokota,Junichi Kikuta,Tomoka Ao,Hiroki Mizuno,Takahiro Matsui,Daisuke Motooka,Ryosuke Yoshizawa,Takashi Nagasawa,Yuzuru Kanakura,Kazuyo Moro,Masaru Ishii, Journal of Experimental Medicine, Rockefeller University Press, Vol. 218, No. 5, 2021/05/03
  • 【難治性免疫疾患-病態解明と新規治療戦略】免疫疾患の病態へのアプローチ マクロファージ研究によって解き明かされてきた難治性免疫疾患の実体, 宮本 佑,菊田 順一,石井 優, 医学のあゆみ, 医歯薬出版(株), Vol. 277, No. 9, p. 682-688, 2021/05
  • SLPI is a critical mediator that controls PTH-induced bone formation., Akito Morimoto,Junichi Kikuta,Keizo Nishikawa,Takao Sudo,Maki Uenaka,Masayuki Furuya,Tetsuo Hasegawa,Kunihiko Hashimoto,Hiroyuki Tsukazaki,Shigeto Seno,Akira Nakamura,Daisuke Okuzaki,Fuminori Sugihara,Akinori Ninomiya,Takeshi Yoshimura,Ryoko Takao-Kawabata,Hideo Matsuda,Masaru Ishii, Nature communications, Vol. 12, No. 1, p. 2136-2136, 2021/04/09
  • Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis., Suguru Takeuchi,Atsunori Tsuchiya,Takahiro Iwasawa,Shunsuke Nojiri,Takayuki Watanabe,Masahiro Ogawa,Tomoaki Yoshida,Katsunori Fujiki,Yuta Koui,Taketomo Kido,Yusuke Yoshioka,Mayu Fujita,Junichi Kikuta,Tohru Itoh,Masaaki Takamura,Katsuhiko Shirahige,Masaru Ishii,Takahiro Ochiya,Atsushi Miyajima,Shuji Terai, NPJ Regenerative medicine, Vol. 6, No. 1, p. 19-19, 2021/03/30
  • Development of an intravital imaging system for the synovial tissue reveals the dynamics of CTLA-4 Ig in vivo, Tetsuo Hasegawa,Junichi Kikuta,Takao Sudo,Erika Yamashita,Shigeto Seno,Tsutomu Takeuchi,Masaru Ishii, Scientific Reports, Springer Science and Business Media LLC, Vol. 10, No. 1, 2020/12
  • In vivo dynamic analysis of BMP-2-induced ectopic bone formation, Kunihiko Hashimoto,Takashi Kaito,Masayuki Furuya,Shigeto Seno,Daisuke Okuzaki,Junichi Kikuta,Hiroyuki Tsukazaki,Hideo Matsuda,Hideki Yoshikawa,Masaru Ishii, Scientific Reports, Vol. 10, No. 1, 2020/12/01
  • Intravital imaging of orthotopic and ectopic bone., Kunihiko Hashimoto,Takashi Kaito,Junichi Kikuta,Masaru Ishii, Inflammation and regeneration, Vol. 40, No. 1, p. 26-26, 2020/11/02
  • 【膠原病・自己免疫疾患を「見える化」する】基礎から見える化する 骨関節破壊を見える化する, 鎗 伸弥,菊田 順一,石井 優, Medicina, (株)医学書院, Vol. 57, No. 12, p. 2145-2149, 2020/11
  • 臨床医が知っておくべき最新の基礎免疫学(第9回) 生体イメージング研究により明らかになったこと, 粟生 智香,菊田 順一,石井 優, 医学のあゆみ, 医歯薬出版(株), Vol. 275, No. 3, p. 295-301, 2020/10
  • 生体イメージングによる細胞動態ネットワークの解明, 宮本 佑,菊田 順一,石井 優, 生化学, (公社)日本生化学会, Vol. 92, No. 5, p. 706-716, 2020/10
  • 骨免疫学研究最前線 骨免疫イメージングアップデート, 菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 38回, p. 97-97, 2020/10
  • 生体骨イメージングで解く破骨細胞の分化制御機構, 菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 38回, p. 103-103, 2020/10
  • SLPIは、骨芽細胞と破骨細胞間の相互作用を調節し、PTHによる骨形成を促進する, 森本 彬人,石井 優,菊田 順一, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 38回, p. 130-130, 2020/10
  • 局所の交感神経は急性炎症の初期において骨髄からの好中球の動員を促進する, 粟生 智香,菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 38回, p. 142-142, 2020/10
  • 「骨の中の生きたままでのイメージング系」を駆使した新しい研究展開, 森本 彬人,菊田 順一,石井 優, 臨床免疫・アレルギー科, (有)科学評論社, Vol. 74, No. 3, p. 288-293, 2020/09
  • 骨破壊・免疫炎症の生体イメージング解析, 菊田 順一,石井 優, 日本腎臓学会誌, (一社)日本腎臓学会, Vol. 62, No. 6, p. 503-503, 2020/09
  • An Acid Activatable Fluorescence Probe for Imaging Osteocytic Bone Resorption Activity in Deep Bone Cavities, Ryu Hashimoto,Masafumi Minoshima,Junichi Kikuta,Shinya Yari,Steven D. Bull,Masaru Ishii,Kazuya Kikuchi, Angewandte Chemie International Edition, Wiley, 2020/08/03
  • 【細胞競合による生体制御とがん】細胞競合の力学・動態・数理 細胞競合と生体イメージング, 菊田 順一,松井 崇浩,石井 優, 医学のあゆみ, 医歯薬出版(株), Vol. 274, No. 5, p. 531-536, 2020/08
  • 【線維化 慢性疾患のキープロセス 多彩な間質細胞が織りなす組織リモデリング"fibrosis"の理解】(第4章)線維化に対する次世代アプローチ 生体二光子励起イメージングによる線維化のin vivo解析, 宮本 佑,菊田 順一,石井 優, 実験医学, (株)羊土社, Vol. 38, No. 12, p. 2116-2121, 2020/08
  • Nonlinear optics with near-infrared excitation enable real-time quantitative diagnosis of human cervical cancers, Takahiro Matsui,Ryo Tamoto,Akio Iwasa,Masafumi Mimura,Seiji Taniguchi,Tetsuo Hasegawa,Takao Sudo,Hiroki Mizuno,Junichi Kikuta,Ichiro Onoyama,Kaoru Okugawa,Mayu Shiomi,Shinya Matsuzaki,Eiichi Morii,Tadashi Kimura,Kiyoko Kato,Yasujiro Kiyota,Masaru Ishii, Cancer Research, American Association for Cancer Research (AACR), Vol. 80, No. 17, p. canres.0348.2020-canres.0348.2020, 2020/07/23
  • 骨はどのようにして維持されるのか 相反する機能を持つ細胞による動的な制御機構, 鎗 伸弥,菊田 順一,石井 優, 生物物理, (一社)日本生物物理学会, Vol. 60, No. 4, p. 227-230, 2020/07
  • Local sympathetic neurons promote neutrophil egress from the bone marrow at the onset of acute inflammation, Tomoka Ao,Junichi Kikuta,Takao Sudo,Yutaka Uchida,Kenta Kobayashi,Masaru Ishii, International Immunology, Oxford University Press (OUP), 2020/04/23
  • 骨芽細胞・破骨細胞は細胞間接触を介して骨リモデリングを調節する, 古家 雅之,菊田 順一,瀬尾 茂人,前田 拓樹,柏井 将文,海渡 貴司,橋本 国彦,松田 秀雄,菊地 和也,石井 優,吉川 秀樹, 日本整形外科学会雑誌, (公社)日本整形外科学会, Vol. 94, No. 3, p. S1099-S1099, 2020/03
  • 骨芽細胞・破骨細胞は細胞間接触を介して骨リモデリングを調節する, 古家 雅之,菊田 順一,瀬尾 茂人,前田 拓樹,柏井 将文,海渡 貴司,橋本 国彦,松田 秀雄,菊地 和也,石井 優,吉川 秀樹, Journal of Spine Research, (一社)日本脊椎脊髄病学会, Vol. 11, No. 3, p. 521-521, 2020/03
  • 非線形光学現象を用いた組織の可視化と病理組織診断への応用, 松井 崇浩,森井 英一,石井 優, 日本病理学会会誌, (一社)日本病理学会, Vol. 109, No. 1, p. 285-285, 2020/03
  • Intravital multiphoton microscopy as a novel tool in the field of immunopharmacology., Akito Morimoto,Junichi Kikuta,Masaru Ishii, Pharmacology & therapeutics, Vol. 206, p. 107429-107429, 2020/02
  • Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway., Maho Morimatsu,Erika Yamashita,Shigeto Seno,Takao Sudo,Junichi Kikuta,Hiroki Mizuno,Daisuke Okuzaki,Daisuke Motooka,Masaru Ishii, Inflammation and regeneration, Vol. 40, p. 15-15, 2020
  • Application of Imaging Technology to Humans, Takahiro Matsui,Masaru Ishii, Make Life Visible, Springer Singapore, p. 213-218, 2020
  • Tracking and Analysis of FUCCI-Labeled Cells Based on Particle Filters and Time-to-Event Analysis, Kenji Fujimoto,Shigeto Seno,Hironori Shigeta,Tomohiro Mashita,Masaru Ishii,Hideo Matsuda, International Journal of Bioscience, Biochemistry and Bioinformatics, International Academy Publishing (IAP), Vol. 10, No. 2, p. 94-109, 2020
  • Thrombomodulin induces anti-inflammatory effects by inhibiting the rolling adhesion of leukocytes in vivo, Shino Nishizawa,Junichi Kikuta,Shigeto Seno,Masahiro Kajiki,Ryuichi Tsujita,Hiroki Mizuno,Takao Sudo,Tomoka Ao,Hideo Matsuda,Masaru Ishii, Journal of Pharmacological Sciences, 2020/01
  • IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95., Kim H,Takegahara N,Walsh MC,Middleton SA,Yu J,Shirakawa J,Ueda J,Fujihara Y,Ikawa M,Ishii M,Kim J,Choi Y, Bone Research, Vol. 8, p. 5-5, 2020
  • Mesenchymal stem cells cultured under hypoxic conditions had a greater therapeutic effect on mice with liver cirrhosis compared to those cultured under normal oxygen conditions., Yuichi Kojima,Atsunori Tsuchiya,Masahiro Ogawa,Shunsuke Nojiri,Suguru Takeuchi,Takayuki Watanabe,Kenji Nakajima,Yukio Hara,Junji Yamashita,Junichi Kikuta,Masaaki Takamura,Masaru Ishii,Shuji Terai, Regenerative therapy, Vol. 11, p. 269-281, 2019/12
  • Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1., Hasegawa T,Kikuta J,Sudo T,Matsuura Y,Matsui T,Simmons S,Ebina K,Hirao M,Okuzaki D,Yoshida Y,Hirao A,Kalinichenko VV,Yamaoka K,Takeuchi T,Ishii M, Nature immunology, NATURE PUBLISHING GROUP, Vol. 20, No. 12, p. 1631-1643, 2019/12
  • Single-cell transcriptome analysis of mouse leukocytes in inflammatory stimulation, Naoki Osato,Hironori Shigeta,Shigeto Seno,Yutaka Uchida,Junichi Kikuta,Masaru Ishii,Hideo Matsuda, 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), IEEE, p. 1229-1231, 2019/11
  • High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node., Simmons S,Sasaki N,Umemoto E,Uchida Y,Fukuhara S,Kitazawa Y,Okudaira M,Inoue A,Tohya K,Aoi K,Aoki J,Mochizuki N,Matsuno K,Takeda K,Miyasaka M,Ishii M, eLife, ELIFE SCIENCES PUBLICATIONS LTD, Vol. 8, 2019/10
  • Analyzing Leukocyte Migration Trajectories by Deformable Image Matching, Hironori Shigeta,Shigeto Seno,Shino Nishizawa,Yutaka Uchida,Junichi Kikuta,Masaru Ishii,Hideo Matsuda, IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE), p. 94-98, 2019/10
  • 【新しい解析技術の展開】次世代の生体イメージング技術開発, 菊田 順一,松井 崇浩,石井 優, 臨床免疫・アレルギー科, (有)科学評論社, Vol. 72, No. 3, p. 293-298, 2019/09
  • 骨関節破壊の画像評価を極める 生体試料を見る, 菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 37回, p. 118-118, 2019/09
  • pH応答性蛍光プローブを用いた破骨細胞の骨吸収動態の解析, 菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 37回, p. 203-203, 2019/09
  • PTH製剤による骨形成促進メカニズムの網羅的解析, 森本 彬人,菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 37回, p. 223-223, 2019/09
  • 骨関節破壊の画像評価を極める 生体試料を見る, 菊田 順一,石井 優, 日本骨粗鬆症学会雑誌, (一社)日本骨粗鬆症学会, Vol. 5, No. Suppl.1, p. 206-206, 2019/09
  • 【"適応&修復"のサイエンスと臨床応用の最前線】様々な組織・臓器における適応・修復機構の動的イメージング, 菊田 順一,石井 優, 別冊Bio Clinica: 慢性炎症と疾患, (株)北隆館, Vol. 8, No. 1, p. 10-14, 2019/07
  • 生体蛍光観察動画像の深度を考慮した深層学習による細胞追跡精度の改善, 嶋田 彩人,瀬尾 茂人,繁田 浩功,間下 以大,内田 穣,石井 優,松田 秀雄, 情報処理学会論文誌数理モデル化と応用（TOM）, Vol. 12, No. 2, p. 82-91, 2019/07
  • In vivo Multicolor Imaging with Fluorescent Probes Revealed the Dynamics and Function of Osteoclast Proton Pumps, Masafumi Minoshima,Junichi Kikuta,Yuta Omori,Shigeto Seno,Riko Suehara,Hiroki Maeda,Hideo Matsuda,Masaru Ishii,Kazuya Kikuchi, ACS Central Science, Vol. 5, No. 6, p. 1059-1066, 2019/06
  • 【運動器を構成する骨・軟骨・関節・筋肉・靱帯・腱のトピック】骨リモデリングに関する最新のトピック in vivoイメージングから得た新知見, 菊田 順一,石井 優, THE BONE, (株)メディカルレビュー社, Vol. 33, No. 1, p. 51-55, 2019/05
  • 【4D細胞・組織ダイナミクス】イメージング技術と細胞・組織ダイナミクス, 宮本 佑,菊田 順一,石井 優, 炎症と免疫, (株)先端医学社, Vol. 27, No. 3, p. 192-198, 2019/04
  • Mesenchymal Stem Cells and Induced Bone Marrow-Derived Macrophages Synergistically Improve Liver Fibrosis in Mice., Yusuke Watanabe,Atsunori Tsuchiya,Satoshi Seino,Yuzo Kawata,Yuichi Kojima,Shunzo Ikarashi,Philip J Starkey Lewis,Wei-Yu Lu,Junichi Kikuta,Hirokazu Kawai,Satoshi Yamagiwa,Stuart J Forbes,Masaru Ishii,Shuji Terai, Stem cells translational medicine, Vol. 8, No. 3, p. 271-284, 2019/03
  • GPR31-dependent dendrite protrusion of intestinal CX3CR1(+) cells by bacterial metabolites, Morita Naoki,Umemoto Eiji,Fujita Setsuko,Hayashi Akio,Kikuta Junichi,Kimura Ikuo,Haneda Takeshi,Imai Toshio,Inoue Asuka,Mimuro Hitomi,Maeda Yuichi,Kayama Hisako,Okumura Ryu,Aoki Junken,Okada Nobuhiko,Kida Toshiyuki,Ishii Masaru,Nabeshima Ryusuke,Takeda Kiyoshi, NATURE, Vol. 566, No. 7742, p. 110-+, 2019/02/07
  • Imaging the Bone-Immune Cell Interaction in Bone Destruction., Hasegawa T,Kikuta J,Ishii M, Frontiers in immunology, Vol. 10, p. 596-596, 2019
  • Roles of Enhancer RNAs in RANKL-induced Osteoclast Differentiation Identified by Genome-wide Cap-analysis of Gene Expression using CRISPR, Yukako Sakaguchi,Keizo Nishikawa,Shigeto Seno,Hideo Matsuda,Hiroshi Takayanagi,Masaru Ishii, Scientific Reports, Nature Publishing Group, Vol. 8, No. 1, 2018/12/01
  • 【ロコモの最新画像診断】骨の画像診断, 菊田 順一,石井 優, Loco Cure, (株)先端医学社, Vol. 4, No. 4, p. 312-317, 2018/11
  • Intravital imaging with two-photon microscopy reveals cellular dynamics in the ischeamia-reperfused rat heart., Ryohei Matsuura,Shigeru Miyagawa,Satsuki Fukushima,Takasumi Goto,Akima Harada,Yuri Shimozaki,Kazumasa Yamaki,Sho Sanami,Junichi Kikuta,Masaru Ishii,Yoshiki Sawa, Scientific reports, Vol. 8, No. 1, p. 15991-15991, 2018/10/30
  • Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches., Prosun Das,Kylee J Veazey,Hieu T Van,Saakshi Kaushik,Kevin Lin,Yue Lu,Masaru Ishii,Junichi Kikuta,Kai Ge,Andre Nussenzweig,Margarida A Santos, Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 43, 2018/10/23
  • 骨関節破壊の生体イメージング, 菊田 順一,石井 優, リウマチ科, (有)科学評論社, Vol. 60, No. 4, p. 442-446, 2018/10
  • 【アレルギーの分子的基盤研究の新しい展開】口腔粘膜特異的マクロファージサブセットが舌下免疫療法における免疫寛容の誘導に関与する, 青井 啓太,菊田 順一,石井 優, 臨床免疫・アレルギー科, (有)科学評論社, Vol. 70, No. 4, p. 357-360, 2018/10
  • Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation., Masaya Baba,Mitsuhiro Endoh,Wenjuan Ma,Hirofumi Toyama,Akiyoshi Hirayama,Keizo Nishikawa,Keiyo Takubo,Hiroyuki Hano,Hisashi Hasumi,Terumasa Umemoto,Michihiro Hashimoto,Nobuko Irie,Chiharu Esumi,Miho Kataoka,Naomi Nakagata,Tomoyoshi Soga,Masahiro Yao,Tomomi Kamba,Takashi Minami,Masaru Ishii,Toshio Suda, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 33, No. 10, p. 1785-1798, 2018/10
  • Presenilin 1 Regulates NF-κB Activation via Association with Breakpoint Cluster Region and Casein Kinase II., Tanaka Y,Sabharwal L,Ota M,Nakagawa I,Jiang JJ,Arima Y,Ogura H,Okochi M,Ishii M,Kamimura D,Murakami M, Journal of immunology (Baltimore, Md. : 1950), Vol. 201, No. 8, p. 2256-2263, 2018/09
  • The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques., Takahiro Nagatake,Yumiko Shiogama,Asuka Inoue,Junichi Kikuta,Tetsuya Honda,Prabha Tiwari,Takayuki Kishi,Atsushi Yanagisawa,Yosuke Isobe,Naomi Matsumoto,Michiko Shimojou,Sakiko Morimoto,Hidehiko Suzuki,So-Ichiro Hirata,Pär Steneberg,Helena Edlund,Junken Aoki,Makoto Arita,Hiroshi Kiyono,Yasuhiro Yasutomi,Masaru Ishii,Kenji Kabashima,Jun Kunisawa, The Journal of allergy and clinical immunology, Vol. 142, No. 2, p. 470-484, 2018/08
  • In vivo visualisation of different modes of action of biological DMARDs inhibiting osteoclastic bone resorption., Yoshinobu Matsuura,Junichi Kikuta,Yuika Kishi,Tetsuo Hasegawa,Daisuke Okuzaki,Toru Hirano,Masafumi Minoshima,Kazuya Kikuchi,Atsushi Kumanogoh,Masaru Ishii, Annals of the rheumatic diseases, Vol. 77, No. 8, p. 1219-1225, 2018/08
  • 骨代謝・骨免疫(第17回) 生体骨組織イメージング, 菊田 順一,石井 優, 分子リウマチ治療, (株)先端医学社, Vol. 11, No. 3, p. 144-147, 2018/07
  • Rising Stars in Skeletal Biology 二光子励起生体イメージングを用いた骨芽細胞・破骨細胞コミュニケーションの解明, 古家 雅之,菊田 順一,瀬尾 茂人,前田 拓樹,吉川 秀樹,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 36回, p. 117-117, 2018/07
  • Chiral cell sliding drives left-right asymmetric organ twisting., Mikiko Inaki,Ryo Hatori,Naotaka Nakazawa,Takashi Okumura,Tomoki Ishibashi,Junichi Kikuta,Masaru Ishii,Kenji Matsuno,Hisao Honda, eLife, Vol. 7, 2018/06/12
  • Claudin-3 Loss Causes Leakage of Sweat from the Sweat Gland to Contribute to the Pathogenesis of Atopic Dermatitis, Kosuke Yamaga,Hiroyuki Murota,Atsushi Tamura,Hirofumi Miyata,Masato Ohmi,Junichi Kikuta,Masaru Ishii,Sachiko Tsukita,Ichiro Katayama, Journal of Investigative Dermatology, Elsevier B.V., Vol. 138, No. 6, p. 1279-1287, 2018/06/01
  • エクリン汗腺の構造と動態観察による発汗制御メカニズムの解明, 室田 浩之,谷 佐起,山賀 康右,小野 慧美,田村 淳,菊田 順一,近江 雅人,月田 早智子,石井 優,関口 清俊,片山 一朗, 日本皮膚科学会雑誌, (公社)日本皮膚科学会, Vol. 128, No. 5, p. 1173-1173, 2018/05
  • 生体骨イメージング技術と計測解析の最前線 生体骨イメージングで見る破骨細胞・骨芽細胞間の4D相互作用, 古家 雅之,菊田 順一,瀬尾 茂人,前田 拓樹,吉川 秀樹,石井 優, 日本骨形態計測学会雑誌, 日本骨形態計測学会, Vol. 28, No. 2, p. S57-S57, 2018/05
  • pH感受性赤色蛍光プローブを用いた破骨細胞プロトンポンプ動態のイメージング, 蓑島 維文,大森 雄太,菊田 順一,石井 優,菊地 和也, JSMI Report, 日本分子イメージング学会, Vol. 11, No. 2, p. 70-70, 2018/05
  • Dynamic Analyses of the Short-Term Effects of Different Bisphosphonates Using Intravital Two-Photon Microscopy., Junichi Kikuta,Mai Shirazaki,Takao Sudo,Hiroki Mizuno,Akito Morimoto,Riko Suehara,Masafumi Minoshima,Kazuya Kikuchi,Masaru Ishii, JBMR plus, Vol. 2, No. 6, p. 362-366, 2018/05
  • 【イメージングの最前線】骨疾患のイメージング, 菊田 順一,石井 優, 臨床免疫・アレルギー科, (有)科学評論社, Vol. 69, No. 4, p. 307-311, 2018/04
  • In vivo live imaging of bone cells, Hiroki Mizuno,Junichi Kikuta,Masaru Ishii, Histochemistry and Cell Biology, Springer Verlag, Vol. 149, No. 4, p. 417-422, 2018/04/01
  • In vivo imaging of T cell lymphoma infiltration process at the colon., Yoshibumi Ueda,Toshiyuki Ishiwata,Seiichi Shinji,Tomio Arai,Yoko Matsuda,Junko Aida,Naotoshi Sugimoto,Toshiro Okazaki,Junichi Kikuta,Masaru Ishii,Moritoshi Sato, Scientific reports, Vol. 8, No. 1, p. 3978-3978, 2018/03/05
  • 【脂質メディエーターと病態】S1Pと骨病態, 菊田 順一,石井 優, 細胞, (株)ニュー・サイエンス社, Vol. 50, No. 3, p. 136-139, 2018/03
  • 「アレルギーの臨床」に寄せる 骨・関節の生体イメージングによる骨破壊の病態解明, 菊田 順一,石井 優, アレルギーの臨床, (株)北隆館, Vol. 38, No. 2, p. 196-198, 2018/02
  • 【運動器系の制御機構と破綻】可視化技術による運動器系組織のダイナミズム, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 28, No. 3, p. 367-371, 2018/02
  • Direct cell-cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo., Masayuki Furuya,Junichi Kikuta,Sayumi Fujimori,Shigeto Seno,Hiroki Maeda,Mai Shirazaki,Maki Uenaka,Hiroki Mizuno,Yoriko Iwamoto,Akito Morimoto,Kunihiko Hashimoto,Takeshi Ito,Yukihiro Isogai,Masafumi Kashii,Takashi Kaito,Shinsuke Ohba,Ung-Il Chung,Alexander C Lichtler,Kazuya Kikuchi,Hideo Matsuda,Hideki Yoshikawa,Masaru Ishii, Nature communications, Vol. 9, No. 1, p. 300-300, 2018/01/19
  • 【リウマチ・膠原病の画像診断の進歩】生体イメージングで関節リウマチの病態を可視化する, 菊田 順一,石井 優, 分子リウマチ治療, (株)先端医学社, Vol. 11, No. 1, p. 25-28, 2018/01
  • 【生体骨イメージング最前線～新しい創薬に向けて～】生体骨イメージングの基礎, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 28, No. 2, p. 175-179, 2018/01
  • 【生体骨イメージング最前線～新しい創薬に向けて～】生体骨イメージングの実際 破骨細胞, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 28, No. 2, p. 211-216, 2018/01
  • 【生体骨イメージング最前線～新しい創薬に向けて～】生体骨イメージングによる骨吸収抑制薬の作用解析, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 28, No. 2, p. 237-242, 2018/01
  • 【生体骨イメージング最前線～新しい創薬に向けて～】生体骨イメージングによる骨形成促進薬の作用解析, 森本 彬人,菊田 順一,古家 雅之,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 28, No. 2, p. 243-248, 2018/01
  • [Development of intravital bone tissue imaging and future perspectives of new lines of therapies for bone diseases.], Ishii M, Clinical calcium, Vol. 28, No. 2, p. 167-174, 2018
  • [Basis of intravital bone imaging.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 175-179, 2018
  • [Development of methodology for living bone imaging.], Mizuno H,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 181-185, 2018
  • [Intravital bone imaging:osteoclast.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 211-216, 2018
  • [In vivo imaging of osteoblasts.], Uenaka M,Mizuno H,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 217-222, 2018
  • [The effects of anti-bone-resorptive drugs analyzed by intravital bone imaging.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 237-242, 2018
  • [Analysis of the bone anabolic agent by intravital imaging technique.], Morimoto A,Kikuta J,Furuya M,Ishii M, Clinical calcium, Vol. 28, No. 2, p. 243-248, 2018
  • Bone imaging: Osteoclast and osteoblast dynamics, Junichi Kikuta,Masaru Ishii, Methods in Molecular Biology, Humana Press Inc., Vol. 1763, p. 1-9, 2018
  • Intravital imaging of liver cell dynamics, Sayaka Matsumoto,Junichi Kikuta,Masaru Ishii, Methods in Molecular Biology, Humana Press Inc., Vol. 1763, p. 137-143, 2018
  • [Homeostasis and Disorder of Musculoskeletal System.Cellular dynamics in musculoskeletal system visualized by intravital imaging techniques.], Kikuta J,Ishii M, Clinical calcium, Vol. 28, No. 3, p. 367-371, 2018
  • Intravital imaging of the heart at the cellular level using two-photon microscopy, Ryohei Matsuura,Shigeru Miyagawa,Junichi Kikuta,Masaru Ishii,Yoshiki Sawa, Methods in Molecular Biology, Humana Press Inc., Vol. 1763, p. 145-151, 2018
  • 生体イメージング技術による時空間情報を保持した1細胞遺伝子解析, 尾上 ひかる,菊田 順一,粟生 智香,内田 穣,石井 優, 生命科学系学会合同年次大会, 生命科学系学会合同年次大会運営事務局, Vol. 2017年度, p. [3AT25-1442)], 2017/12
  • 【ビタミンD Update】自己免疫疾患におけるビタミンD 基礎研究から臨床応用まで, 粟生 智香,菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 27, No. 11, p. 1551-1559, 2017/10
  • Bone marrow cavity segmentation using graph-cuts with wavelet-based texture feature, Hironori Shigeta,Tomohiro Mashita,Junichi Kikuta,Shigeto Seno,Haruo Takemura,Masaru Ishii,Hideo Matsuda, JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, IMPERIAL COLLEGE PRESS, Vol. 15, No. 5, 2017/10
  • Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions., Takahiro Matsui,Hiroki Mizuno,Takao Sudo,Junichi Kikuta,Naotsugu Haraguchi,Jun-Ichiro Ikeda,Tsunekazu Mizushima,Hirofumi Yamamoto,Eiichi Morii,Masaki Mori,Masaru Ishii, Scientific reports, Vol. 7, No. 1, p. 6959-6959, 2017/07/31
  • 【骨免疫学の進歩が変える骨関節疾患アプローチ】免疫細胞と骨代謝 免疫細胞による骨代謝制御 生体イメージング, 菊田 順一,石井 優, THE BONE, (株)メディカルレビュー社, Vol. 31, No. 2, p. 151-155, 2017/07
  • Immunology proves a great success for treating systemic autoimmune diseases - a perspective on immunopharmacology: IUPHAR Review 23, Masaru Ishii, BRITISH JOURNAL OF PHARMACOLOGY, WILEY, Vol. 174, No. 13, p. 1875-1880, 2017/07
  • 「リウマチ・膠原病とアレルギー疾患」に寄せる 生体イメージング技術による骨・関節疾患の病態解明, 菊田 順一,石井 優, アレルギーの臨床, (株)北隆館, Vol. 37, No. 5, p. 487-489, 2017/05
  • pH感受性赤色蛍光プローブを用いた生体内破骨細胞活性リアルタイムイメージング, 蓑島 維文,大森 雄太,前田 拓樹,菊田 順一,石井 優,菊地 和也, JSMI Report, 日本分子イメージング学会, Vol. 10, No. 2, p. 128-128, 2017/05
  • Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes, Shunsuke Kon,Kojiro Ishibashi,Hiroto Katoh,Sho Kitamoto,Takanobu Shirai,Shinya Tanaka,Mihoko Kajita,Susumu Ishikawa,Hajime Yamauchi,Yuta Yako,Tomoko Kamasaki,Tomohiro Matsumoto,Hirotaka Watanabe,Riku Egami,Ayana Sasaki,Atsuko Nishikawa,Ikumi Kameda,Takeshi Maruyama,Rika Narumi,Tomoko Morita,Yoshiteru Sasaki,Ryosuke Enoki,Sato Honma,Hiromi Imamura,Masanobu Oshima,Tomoyoshi Soga,Jun-ichi Miyazaki,Michael R. Duchen,Jin-Min Nam,Yasuhito Onodera,Shingo Yoshioka,Junichi Kikuta,Masaru Ishii,Masamichi Imajo,Eisuke Nishida,Yoichiro Fujioka,Yusuke Ohba,Toshiro Sato,Yasuyuki Fujita, NATURE CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 19, No. 5, p. 530-+, 2017/05
  • Roles for Cell-Cell Adhesion and Contact in Obesity- Induced Hepatic Myeloid Cell Accumulation and Glucose Intolerance, Yasutaka Miyachi,Kyoichiro Tsuchiya,Chikara Komiya,Kumiko Shiba,Noriko Shimazu,Shinobu Yamaguchi,Michiyo Deushi,Mizuko Osaka,Kouji Inoue,Yuta Sato,Sayaka Matsumoto,Junichi Kikuta,Kenjiro Wake,Masayuki Yoshida,Masaru Ishii,Yoshihiro Ogawa, CELL REPORTS, CELL PRESS, Vol. 18, No. 11, p. 2766-2779, 2017/03
  • [Update on recent progress in vitamin D research. The effects of vitamin D in autoinflammatory diseases.], Ao T,Kikuta J,Ishii M, Clinical calcium, Vol. 27, No. 11, p. 1551-1559, 2017
  • Imaging of bone and joint destruction, Junichi Kikuta,Masaru Ishii, Japanese Journal of Clinical Immunology, Japan Society for Clinical Immunology, Vol. 40, No. 5, p. 344-351, 2017
  • Imaging of inflammation and regeneration: a novel trend dissecting dynamic features of biological phenomena in vivo., Ishii M, Inflammation and regeneration, Vol. 37, 2017
  • 【慢性炎症性疾患の新たな展開】慢性炎症の病的意義 骨代謝と慢性炎症, 菊田 順一,松浦 良信,石井 優, 最新医学, (株)最新医学社, Vol. 71, No. 11月増刊, p. 2257-2262, 2016/11
  • イムノメタボリズムと肥満症 イムノメタボリズムにおけるS100A8の位置付け, 前田 法一,堰本 亮平,福田 士郎,船橋 徹,石井 優,下村 伊一郎, 肥満研究, (一社)日本肥満学会, Vol. 22, No. Suppl., p. 154-154, 2016/09
  • 模様特徴量とグラフカットを利用した生体骨組織の骨髄腔の領域分割, 繁田 浩功,間下 以大,菊田 順一,瀬尾 茂人,石井 優,松田 秀雄, 2016/09
  • 病理アトラス 膠原病・アレルギー疾患の可視化, 菊田 順一,石井 優, 別冊Bio Clinica: 慢性炎症と疾患, (株)北隆館, Vol. 5, No. 3, p. 1-4, 2016/08
  • Real-time intravital imaging of pH variation associated with osteoclast activity, Hiroki Maeda,Toshiyuki Kowada,Junichi Kikuta,Masayuki Furuya,Mai Shirazaki,Shin Mizukami,Masaru Ishii,Kazuya Kikuchi, NATURE CHEMICAL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 12, No. 8, p. 579-+, 2016/08
  • Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5 beta complex in migrating cells, Boon Cheng Lim,Shinji Matsumoto,Hideki Yamamoto,Hiroki Mizuno,Junichi Kikuta,Masaru Ishii,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 129, No. 16, p. 3115-3129, 2016/08
  • Cell-cycle-controlled radiation therapy was effective for treating a murine malignant melanoma cell line in vitro and in vivo, Keisuke Otani,Yoko Naito,Yukako Sakaguchi,Yuji Seo,Yutaka Takahashi,Junichi Kikuta,Kazuhiko Ogawa,Masaru Ishii, Scientific Reports, NATURE PUBLISHING GROUP, Vol. 6, 2016/08
  • 【骨リモデリングの制御機構】骨芽細胞と破骨細胞の生体イメージング観察, 菊田 順一,古家 雅之,石井 優, THE BONE, (株)メディカルレビュー社, Vol. 30, No. 2, p. 141-144, 2016/07
  • 汗腺の構造/機能解析の最前線 Claudin-3が汗腺からの汗の漏出を止める, 山賀 康右,室田 浩之,宮田 浩史,近江 雅人,菊田 順一,石井 優,田村 淳,月田 早智子,片山 一朗, 日本発汗学会総会プログラム・抄録集, 日本発汗学会, Vol. 24回, p. 31-31, 2016/07
  • Intravital imaging technology reveals immune system dynamics in vivo, Masaru Ishii, ALLERGOLOGY INTERNATIONAL, JAPANESE SOCIETY ALLERGOLOGY, Vol. 65, No. 3, p. 225-227, 2016/07
  • 骨小腔・骨細管のin vivoイメージング, 佐野 博繁,菊田 順一,古家 雅之,近藤 直樹,藤澤 純一,木島 靖文,遠藤 直人,石井 優, 日本骨形態計測学会雑誌, 日本骨形態計測学会, Vol. 26, No. 1, p. S148-S148, 2016/06
  • ウェーブレット特徴量を用いた生体骨組織の骨髄腔の領域分割手法, 繁田浩功,間下以大,菊田順一,瀬尾茂人,竹村治雄,松田秀雄,石井優, 2016/06
  • Intercellular Communication between Keratinocytes and Fibroblasts Induces Local Osteoclast Differentiation: a Mechanism Underlying Cholesteatoma-Induced Bone Destruction, Yoriko Iwamoto,Keizo Nishikawa,Ryusuke Imai,Masayuki Furuya,Maki Uenaka,Yumi Ohta,Tetsuo Morihana,Saori Itoi-Ochi,Josef M. Penninger,Ichiro Katayama,Hidenori Inohara,Masaru Ishii, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 36, No. 11, p. 1610-1620, 2016/06
  • [Analysis of bone tissues by intravital imaging]., Hiroki Mizuno,Erika Yamashita,Masaru Ishii, Clinical calcium, Vol. 26, No. 5, p. 729-34, 2016/05
  • pH感受性蛍光プローブを用いた生体内破骨細胞活性リアルタイムイメージング, 大森 雄太,前田 拓樹,小和田 俊行,菊田 順一,古家 雅之,石井 優,菊地 和也, JSMI Report, 日本分子イメージング学会, Vol. 9, No. 2, p. 134-134, 2016/04
  • 【慢性炎症と自己免疫疾患】生体イメージングで捉える免疫炎症・骨破壊の動的な実体, 菊田 順一,石井 優, 日本臨床免疫学会会誌, (一社)日本臨床免疫学会, Vol. 39, No. 2, p. 124-129, 2016/04
  • 脂肪組織炎症におけるS100A8の意義, 前田 法一,堰本 亮平,福田 士郎,對馬 佑,松田 圭介,森 卓也,中辻 秀朗,西澤 均,岸田 堅,菊田 順一,舞島 弓子,船橋 徹,石井 優,下村 伊一郎, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 92, No. 1, p. 214-214, 2016/04
  • Intravital imaging of the cellular dynamics of LysM-positive cells in a murine corneal suture model, Mayumi Ueta,Ayaka Koga,Junichi Kikuta,Keiko Yamada,Sachi Kojima,Katsuhiko Shinomiya,Masaru Ishii,Shigeru Kinoshita, BRITISH JOURNAL OF OPHTHALMOLOGY, BMJ PUBLISHING GROUP, Vol. 100, No. 3, p. 432-435, 2016/03
  • Visualization of Intravital Immune Cell Dynamics After Conjunctival Surgery Using Multiphoton Microscopy, Sachi Kojima,Toshihiro Inoue,Junichi Kikuta,Masayuki Furuya,Ayaka Koga,Tomokazu Fujimoto,Mayumi Ueta,Shigeru Kinoshita,Masaru Ishii,Hidenobu Tanihara, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Vol. 57, No. 3, p. 1207-1212, 2016/03
  • Involvement of Receptor Activator of Nuclear Factor-B Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts, Noriko Takegahara,Hyunsoo Kim,Hiroki Mizuno,Asako Sakaue-Sawano,Atsushi Miyawaki,Michio Tomura,Osami Kanagawa,Masaru Ishii,Yongwon Choi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 291, No. 7, p. 3439-3454, 2016/02
  • Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility, Akira Takeda,Daichi Kobayashi,Keita Aoi,Naoko Sasaki,Yuki Sigiura,Hidemitsu Igarashi,Kazuo Tohya,Asuka Inoue,Erina Hata,Noriyuki Akahoshi,Haruko Hayasaka,Junichi Kikuta,Elke Scandella,Brukhard Ludewig,Satoshi Ishii,Junken Aoki,Makoto Suematsu,Masaru Ishii,Kiyoshi Takeda,Sirpa Jalkanen,Masayuki Miyasaka,Eiji Umemoto, ELIFE, ELIFE SCIENCES PUBLICATIONS LTD, Vol. 5, 2016/02
  • A Bone Marrow Cavity Segmentation Method using Wavelet-based Texture Feature, Hironori Shigeta,Tomohiro Mashita,Junichi Kikutat,Shigeto Seno,Haruo Takemura,Hideo Matsuda,Masaru Ishii, 2016 23RD INTERNATIONAL CONFERENCE ON PATTERN RECOGNITION (ICPR), IEEE COMPUTER SOC, p. 2133-2138, 2016
  • Intravital imaging of Ca2+ signals in lymphocytes of Ca2+ biosensor transgenic mice: indication of autoimmune diseases before the pathological onset, Soichiro Yoshikawa,Takako Usami,Junichi Kikuta,Masaru Ishii,Tetsuo Sasano,Koji Sugiyama,Tetsushi Furukawa,Eiji Nakasho,Hiroshi Takayanagi,Thomas F. Tedder,Hajime Karasuyama,Atsushi Miyawaki,Takahiro Adachi, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 6, 2016/01
  • Dynamic analysis of immune inflammation and bone destruction by intravital imaging., Kikuta J,Ishii M, Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, Vol. 39, No. 2, p. 124-129, 2016
  • 生体イメージング技術を駆使したトロンボモジュリンの新たな作用機序解明, 西澤 志乃,菊田 順一,瀬尾 茂人,松田 秀雄,石井 優, 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, (公社)日本生化学会, Vol. 88回・38回, p. [3T23p-05(3P0080)], 2015/12
  • 最新基礎科学 知っておきたい ビタミンDの骨吸収抑制機序, 菊田 順一,石井 優, 臨床整形外科, (株)医学書院, Vol. 50, No. 11, p. 1114-1117, 2015/11
  • Adipose tissue macrophages induce PPAR gamma- high FOXP3+regulatory T cells, Toshiharu Onodera,Atsunori Fukuhara,Myoung Ho Jang,Jihoon Shin,Keita Aoi,Junichi Kikuta,Michio Otsuki,Masaru Ishii,Iichiro Shimomura, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 5, 2015/11
  • Trafficking of Osteoclast Precursors, Junichi Kikuta,Erin Nevius,Masaru Ishii,João P. Pereira, Osteoimmunology: Interactions of the Immune and Skeletal Systems: Second Edition, Elsevier Inc., p. 25-40, 2015/10/06
  • IL-6から見える景色(第9回) IL-6と骨破壊 反応編(4), 松浦 良信,菊田 順一,石井 優, Keynote R・A, (株)先端医学社, Vol. 3, No. 4, p. 190-191, 2015/10
  • Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing, Nathan P. Manes,Bastian R. Angermann,Marijke Koppenol-Raab,Eunkyung An,Virginie H. Sjoelund,Jing Sun,Masaru Ishii,Ronald N. Germain,Martin Meier-Schellersheim,Aleksandra Nita-Lazar, MOLECULAR & CELLULAR PROTEOMICS, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 14, No. 10, p. 2661-2681, 2015/10
  • Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis, Erin Nevius,Flavia Pinho,Meera Dhodapkar,Huiyan Jin,Kristina Nadrah,Mark C. Horowitz,Junichi Kikuta,Masaru Ishii,Joao P. Pereira, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 212, No. 11, p. 1931-1946, 2015/10
  • 脂肪組織慢性炎症のinitial triggerとしてのS100A8の意義, 前田 法一,堰本 亮平,福田 士郎,對馬 佑,松田 圭介,森 卓也,中辻 秀朗,西澤 均,岸田 堅,菊田 順一,舞島 弓子,船橋 徹,石井 優,下村 伊一郎, 肥満研究, (一社)日本肥満学会, Vol. 21, No. Suppl., p. 175-175, 2015/09
  • The expanding role of immunopharmacology: IUPHAR Review 16, Ekaterini Tiligada,Masaru Ishii,Carlo Riccardi,Michael Spedding,Hans-Uwe Simon,Mauro Martins Teixeira,Mario Landys Chovel Cuervo,Stephen T. Holgate,Francesca Levi-Schaffer, BRITISH JOURNAL OF PHARMACOLOGY, WILEY, Vol. 172, No. 17, p. 4217-4227, 2015/09
  • 骨の4Dイメージング 骨のライブイメージング最前線, 菊田 順一,水野 紘樹,古家 雅之,石井 優, O.li.v.e., (株)メディカルレビュー社, Vol. 5, No. 3, p. 208-211, 2015/08
  • in vivoイメージングを用いた骨細胞性骨溶解機序解明への試み, 佐野 博繁,菊田 順一,古家 雅之,近藤 直樹,遠藤 直人,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 33回, p. 166-166, 2015/07
  • RFPL4Aは静止期維持機構を持ち抗がん剤抵抗性の原因となる, 内藤 敦,植村 守,西村 潤一,畑 泰司,竹政 伊知郎,水島 恒和,山本 浩文,土岐 祐一郎,石井 優,森 正樹, 日本消化器外科学会総会, (一社)日本消化器外科学会, Vol. 70回, p. P-5, 2015/07
  • Significance of Polypyrimidine Tract-Binding Protein 1 Expression in Colorectal Cancer., Hidekazu Takahashi,Junichi Nishimura,Yoshinori Kagawa,Yoshihiro Kano,Yusuke Takahashi,Xin Wu,Masayuki Hiraki,Atsushi Hamabe,Masamitsu Konno,Naotsugu Haraguchi,Ichiro Takemasa,Tsunekazu Mizushima,Masaru Ishii,Koshi Mimori,Hideshi Ishii,Yuichiro Doki,Masaki Mori,Hirofumi Yamamoto, Molecular cancer therapeutics, Vol. 14, No. 7, p. 1705-16, 2015/07
  • Imaging and hematopoiesis/oncogenesis 生体骨組織を用いた多光子励起イメージングによるin vivo造血細胞の動態解析, 水野 紘樹,菊田 順一,古家 雅之,石井 優, 臨床血液, (一社)日本血液学会-東京事務局, Vol. 56, No. 6, p. 594-600, 2015/06
  • コンポーネントツリーを用いたグローバルデータアソシエーションによる細胞追跡手法, Kohei Kurashige,Shigeto Seno,Tomohiro Mashita,Junichi Kikuta,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2015/06
  • [Frontiers in Live Bone Imaging Researches. Intravital imaging of osteoclast dynamics]., Kikuta J,Ishii M, Clinical calcium, Vol. 25, No. 6, p. 815-822, 2015/06
  • [Frontiers in Live Bone Imaging Researches. In vivo imaging of osteoblasts]., Furuya M,Ishii M, Clinical calcium, Vol. 25, No. 6, p. 823-830, 2015/06
  • [Frontiers in Live Bone Imaging Researches. In vivo imaging of bone marrow microenvironment]., Mizuno H,Ishii M, Clinical calcium, Vol. 25, No. 6, p. 831-836, 2015/06
  • [Frontiers in Live Bone Imaging Researches. Novel drug discovery by means of intravital bone imaging technology]., Ishii M, Clinical calcium, Vol. 25, No. 6, p. 907-913, 2015/06
  • [Intravital multiphoton imaging of live bone tissues revealing hematopoietic cell dynamics in vivo]., Mizuno H,Kikuta J,Furuya M,Ishii M, [Rinsho ketsueki] The Japanese journal of clinical hematology, Vol. 56, No. 6, p. 594-600, 2015/06
  • [In vivo imaging of bones--New era for research of bones]., Ishii M, Clinical calcium, Vol. 25, No. 6, 2015/06
  • 【骨の生体イメージング 最前線】破骨細胞の生体イメージング, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 25, No. 6, p. 815,789-790, 2015/05
  • Intravital bone imaging by two-photon excitation microscopy to identify osteocytic osteolysis in vivo, Hiroshige Sano,Junichi Kikuta,Masayuki Furuya,Naoki Kondo,Naoto Endo,Masaru Ishii, BONE, ELSEVIER SCIENCE INC, Vol. 74, p. 134-139, 2015/05
  • 下部消化管 Fucci systemを用いた静止期維持因子の解析, 内藤 敦,植村 守,西村 潤一,畑 泰司,竹政 伊知朗,水島 恒和,山本 浩文,土岐 祐一郎,石井 優,森 正樹, 日本外科学会定期学術集会抄録集, (一社)日本外科学会, Vol. 115回, p. OP-5, 2015/04
  • Visualized macrophage dynamics and significance of S100A8 in obese fat, Ryohei Sekimoto,Shiro Fukuda,Norikazu Maeda,Yu Tsushima,Keisuke Matsuda,Takuya Mori,Hideaki Nakatsuji,Hitoshi Nishizawa,Ken Kishida,Junichi Kikuta,Yumiko Maijima,Tohru Funahashi,Masaru Ishii,Iichiro Shimomura, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 112, No. 16, p. E2058-E2066, 2015/04
  • 【骨転移病変に対する最新の基礎的知見と臨床マネージメント】固形癌転移と骨微小環境をめぐる最新の基礎研究 破骨細胞イメージングによる骨破壊メカニズムの解明, 菊田 順一,石井 優, Surgery Frontier, (株)メディカルレビュー社, Vol. 22, No. 1, p. 28,3-4, 2015/03
  • A Bone Marrow Recognition Method for Bone Tissue Images using Wavelet Transform, Hironori Shigeta,Tomohiro Mashita,Takeshi Kaneko,Junichi Kikuta,Shigeto Senoo,Haruo Takemura,Hideo Matsuda,Masaru Ishii, 2015/03
  • A Bone-marrow Space Segmentation Method Using Graph-cuts, Information Processing Society of Japan (IPSJ), Vol. 8, No. 1, p. 18-27, 2015/03
  • RFPL4A Increases the G(1) Population and Decreases Sensitivity to Chemotherapy in Human Colorectal Cancer Cells, Atsushi Naito,Hirofumi Yamamoto,Yoshinori Kagawa,Yoko Naito,Daisuke Okuzaki,Keisuke Otani,Yoriko Iwamoto,Sakae Maeda,Junichi Kikuta,Keizo Nishikawa,Mamoru Uemura,Junichi Nishimura,Taishi Hata,Ichiro Takemasa,Tsunekazu Mizushima,Hideshi Ishii,Yuichiro Doki,Masaki Mori,Masaru Ishii, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 290, No. 10, p. 6326-6337, 2015/03
  • DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine-producing metabolic pathway, Keizo Nishikawa,Yoriko Iwamoto,Yasuhiro Kobayashi,Fumiki Katsuoka,Shin-ichi Kawaguchi,Tadayuki Tsujita,Takashi Nakamura,Shigeaki Kato,Masayuki Yamamoto,Hiroshi Takayanagi,Masaru Ishii, NATURE MEDICINE, NATURE PUBLISHING GROUP, Vol. 21, No. 3, p. 281-+, 2015/03
  • [Current Topics on Vitamin D. The effects of vitamin D on the immune system]., Kikuta J,Ishii M, Clinical calcium, Vol. 25, No. 3, p. 359-365, 2015/03
  • 【ビタミンDをめぐる最近の話題】ビタミンDの免疫細胞への作用と感染防御, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 25, No. 3, p. 359-365, 2015/02
  • 病理アトラス 生体イメージングによる炎症病態の機能的解析, 水野 紘樹,菊田 順一,石井 優, 別冊Bio Clinica: 慢性炎症と疾患, (株)北隆館, Vol. 4, No. 1, p. np1-np4, 2015/02
  • Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient, Xiaowen Liu,Tao Yang,Koya Suzuki,Sachiko Tsukita,Masaru Ishii,Shuping Zhou,Gang Wang,Luyang Cao,Feng Qian,Shalina Taylor,Myung-Jin Oh,Irena Levitan,Richard D. Ye,Graeme K. Carnegie,Yong Zhao,Asrar B. Malik,Jingsong Xu, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 212, No. 2, p. 267-280, 2015/02
  • Transplanted Bone Marrow-Derived Circulating PDGFR alpha(+) Cells Restore Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa Mouse Skin Graft, Shin Iinuma,Eriko Aikawa,Katsuto Tamai,Ryo Fujita,Yasushi Kikuchi,Takenao Chino,Junichi Kikuta,John A. McGrath,Jouni Uitto,Masaru Ishii,Hajime Iizuka,Yasufumi Kaneda, JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 194, No. 4, p. 1996-2003, 2015/02
  • 【骨代謝研究の最前線】イメージングを用いた骨代謝研究, 菊田 順一,石井 優, BIO Clinica, (株)北隆館, Vol. 30, No. 1, p. 23-27, 2015/01
  • 生体骨組織における骨髄腔画像のウェーブレット変換を用いた骨髄腔領域の認識手法, 繁田 浩功,間下 以大,金子 雄,菊田 順一,瀬尾 茂人,竹村 治雄,松田 秀雄,石井 優, 情報処理学会研究報告. CVIM, [コンピュータビジョンとイメージメディア], 一般社団法人情報処理学会, Vol. 2015, No. 42, p. 1-5, 2015/01
  • Sweat, the driving force behind normal skin: An emerging perspective on functional biology and regulatory mechanisms, Hiroyuki Murota,Saki Matsui,Emi Ono,Akiko Kijima,Junichi Kikuta,Masaru Ishii,Ichiro Katayama, JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER IRELAND LTD, Vol. 77, No. 1, p. 3-10, 2015/01
  • 【炎症-全体像を知り慢性疾患を制御する 炎症シグナル、免疫細胞のダイナミズムからがん・糖尿病などの発症機序と治療標的まで】(第1章)炎症応答の時・空間的ダイナミクスと関与する細胞たち 炎症のvisualization, 菊田 順一,石井 優, 実験医学, (株)羊土社, Vol. 32, No. 17, p. 2716-2720, 2014/11
  • 脂肪組織慢性炎症における免疫細胞の動態変化の解析, 堰本 亮平,前田 法一,對馬 佑,松田 圭介,森 卓也,福田 士郎,中辻 秀朗,西澤 均,岸田 堅,菊田 順一,船橋 徹,石井 優,下村 伊一郎, 肥満研究, (一社)日本肥満学会, Vol. 20, No. Suppl., p. 168-168, 2014/10
  • Improvement approach of cell tracking accuracy by using inter-frame information, Kohei Kurashige,Shigeto Seno,Tomohiro Mashita,Junichi Kikuta,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2014/10
  • An automatic event detection method using semi-supervised learning for time-lapse imaging data, Kojiro Fukuda,Shigeto Seno,Tomohiro Mashita,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2014/10
  • A Segmentation Method for Bone Marrow Cavity Image Using Graph-Cuts, Tomohiro Mashita,Jun Usami,Hironori Shigeta,Yoshihiro Kuroda,Junichi Kikuta,Shigeto Senoo,Masaru Ishii,Hideo Matsuda,Haruo Takemura, 2014/09
  • A Graph Cuts Image Segmentation Method for Quantifying Barrier Permeation in Bone Tissue, Hironori Shigeta,Tomohiro Mashita,Takeshi Kaneko,Junichi Kikuta,Shigeto Senoo,Haruo Takemura,Hideo Matsuda,Masaru Ishii, 2014/09
  • Interferon-α acts on the S/G2/M phases to induce apoptosis in the G1 phase of an IFNAR2-expressing hepatocellular carcinoma cell line., Sakae Maeda,Hiroshi Wada,Yoko Naito,Hiroaki Nagano,Szandor Simmons,Yoshinori Kagawa,Atsushi Naito,Junichi Kikuta,Taeko Ishii,Yoshito Tomimaru,Naoki Hama,Koichi Kawamoto,Shogo Kobayashi,Hidetoshi Eguchi,Koji Umeshita,Hideshi Ishii,Yuichiro Doki,Masaki Mori,Masaru Ishii, The Journal of biological chemistry, Vol. 289, No. 34, p. 23786-95, 2014/08/22
  • Left-right asymmetry is formed in individual cells by intrinsic cell chirality, Ryo Hatori,Tadashi Ando,Takeshi Sasamura,Naotaka Nakazawa,Mitsutoshi Nakamura,Kiichiro Taniguchi,Shunya Hozumi,Junichi Kikuta,Masaru Ishii,Kenji Matsuno, MECHANISMS OF DEVELOPMENT, ELSEVIER SCIENCE BV, Vol. 133, p. 146-162, 2014/08
  • 【高齢者脆弱性骨折の予防と治療】病態の最新知見 画像イメージングから, 菊田 順一,古家 雅之,石井 優, 整形外科, (株)南江堂, Vol. 65, No. 8, p. 712-718, 2014/07
  • 骨代謝研究領域におけるバイオイメージング技術の発展からその応用まで 2光子励起顕微鏡を駆使した骨髄イメージング, 菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 32回, p. 160-160, 2014/07
  • 生体二光子励起イメージングによるビスホスホネート製剤の短期的効果の検討, 菊田 順一,白崎 舞,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 32回, p. 205-205, 2014/07
  • 抗癌剤抵抗性をもつ静止期維持因子の解析, 内藤 敦,植村 守,西村 潤一,畑 泰司,竹政 伊知朗,水島 恒和,山本 浩文,土岐 祐一郎,石井 優,森 正樹, 日本消化器外科学会総会, (一社)日本消化器外科学会, Vol. 69回, p. P-2, 2014/07
  • [Bone metabolism and cardiovascular function update. Relationship between immune and vascular system in bone tissues]., Kikuta J,Ishii M, Clinical calcium, Vol. 24, No. 7, p. 63-68, 2014/07
  • Filamin acts as a key regulator in epithelial defence against transformed cells, Mihoko Kajita,Kaoru Sugimura,Atsuko Ohoka,Jemima Burden,Hitomi Suganuma,Masaya Ikegawa,Takashi Shimada,Tetsuya Kitamura,Masanobu Shindoh,Susumu Ishikawa,Sayaka Yamamoto,Sayaka Saitoh,Yuta Yako,Ryosuke Takahashi,Takaharu Okajima,Junichi Kikuta,Yumiko Maijima,Masaru Ishii,Masazumi Tada,Yasuyuki Fujita, NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, Vol. 5, 2014/07
  • 【骨バイオイメージング】動的イメージング 骨髄内細胞動態イメージング(2光子励起顕微鏡を用いて), 菊田 順一,石井 優, THE BONE, (株)メディカルレビュー社, Vol. 28, No. 2, p. 185-190, 2014/06
  • 【骨・血管連関～最近の進歩～】免疫系と骨・血管連関, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 24, No. 7, p. 1031-1036, 2014/06
  • 脂肪組織慢性炎症における免疫細胞の動態変化の解析, 堰本 亮平,前田 法一,對馬 佑,松田 圭介,森 卓也,福田 士郎,中辻 秀朗,西澤 均,岸田 堅,菊田 順一,船橋 徹,石井 優,下村 伊一郎, 日本動脈硬化学会総会プログラム・抄録集, (一社)日本動脈硬化学会, Vol. 46回, p. 320-320, 2014/06
  • Olopatadine hydrochloride restores histamine-induced impaired sweating, Saki Matsui,Hiroyuki Murota,Emi Ono,Junichi Kikuta,Masaru Ishii,Ichiro Katayama, JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER IRELAND LTD, Vol. 74, No. 3, p. 260-261, 2014/06
  • 【骨代謝 つくり、壊し、変える-そのメカニズムと最新治療 分子機構から骨粗鬆症・リウマチなど骨疾患への応用まで】(第I部) 骨代謝制御機構を知る (第3章)骨をみる イメージングの現状と展望 骨組織におけるin vivoイメージング, 菊田 順一,古家 雅之,石井 優, 実験医学, (株)羊土社, Vol. 32, No. 7, p. 1054-1060, 2014/05
  • Development of an in vitro culture method for stepwise differentiation of mouse embryonic stem cells and induced pluripotent stem cells into mature osteoclasts, Keizo Nishikawa,Yoriko Iwamoto,Masaru Ishii, JOURNAL OF BONE AND MINERAL METABOLISM, SPRINGER JAPAN KK, Vol. 32, No. 3, p. 331-336, 2014/05
  • 【最新関節リウマチ学-寛解・治癒を目指した研究と最新治療-】関節リウマチの基礎研究 骨組織の生体多光子励起イメージング, 菊田 順一,石井 優, 日本臨床, (株)日本臨床社, Vol. 72, No. 増刊3 最新関節リウマチ学, p. 178-182, 2014/04
  • 脂肪組織慢性炎症における免疫細胞の動態変化の解析, 堰本 亮平,前田 法一,岸田 堅,中辻 秀朗,福田 士郎,西澤 均,船橋 徹,石井 優,下村 伊一郎, 糖尿病, (一社)日本糖尿病学会, Vol. 57, No. Suppl.1, p. S-446, 2014/04
  • Sphingosine-1-Phosphate: a Master Regulator of Lymphocyte Egress and Immunity, Szandor Simmons,Masaru Ishii, ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, SPRINGER BASEL AG, Vol. 62, No. 2, p. 103-115, 2014/04
  • A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures, Shinji Matsumoto,Shinsuke Fujii,Akira Sato,Souji Ibuka,Yoshinori Kagawa,Masaru Ishii,Akira Kikuchi, EMBO JOURNAL, WILEY-BLACKWELL, Vol. 33, No. 7, p. 702-718, 2014/04
  • [Bone and Stem Cells. Intravital imaging of bone marrow microenvironment]., Mizuno H,Kikuta J,Ishii M, Clinical calcium, Vol. 24, No. 4, p. 541-546, 2014/04
  • Generation of colonic IgA-secreting cells in the caecal patch, Kazunori Masahata,Eiji Umemoto,Hisako Kayama,Manato Kotani,Shota Nakamura,Takashi Kurakawa,Junichi Kikuta,Kazuyoshi Gotoh,Daisuke Motooka,Shintaro Sato,Tomonori Higuchi,Yoshihiro Baba,Tomohiro Kurosaki,Makoto Kinoshita,Yosuke Shimada,Taishi Kimura,Ryu Okumura,Akira Takeda,Masaru Tajima,Osamu Yoshie,Masahiro Fukuzawa,Hiroshi Kiyono,Sidonia Fagarasan,Tetsuya Iida,Masaru Ishii,Kiyoshi Takeda, NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, Vol. 5, 2014/04
  • 【骨と幹細胞】骨髄環境のライブイメージング, 水野 紘樹,菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 24, No. 4, p. 541-546, 2014/03
  • 骨粗鬆症と骨代謝 活性型ビタミンDはS1Pによる破骨前駆細胞の遊走制御機構を調整することにより骨吸収を抑制する, 菊田 順一,石井 優, 日本リウマチ学会総会・学術集会プログラム・抄録集, (一社)日本リウマチ学会, Vol. 58回, p. 387-387, 2014/03
  • Lysophosphatidic Acid Receptor Type 1 (LPA(1)) Plays a Functional Role in Osteoclast Differentiation and Bone Resorption Activity, Marion David,Irma Machuca-Gayet,Junichi Kikuta,Penelope Ottewell,Fuka Mima,Raphael Leblanc,Edith Bonnelye,Johnny Ribeiro,Ingunn Holen,Ruben Lopez Vales,Pierre Jurdic,Jerold Chun,Philippe Clezardin,Masaru Ishii,Olivier Peyruchaud, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 289, No. 10, p. 6551-6564, 2014/03
  • Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress., Koyu Ito,Junko Morimoto,Akio Kihara,Yutaka Matsui,Daisuke Kurotaki,Masashi Kanayama,Szandor Simmons,Masaru Ishii,Dean Sheppard,Akinori Takaoka,Toshimitsu Uede, Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 8, p. 3080-5, 2014/02/25
  • 【細胞の3次元組織化-その最先端技術と材料技術 再生医療とその支援分野(細胞研究、創薬研究)への応用と発展のために】(第4章)細胞3次元組織化培養のための周辺技術 ライブイメージング, 水野 紘樹,菊田 順一,石井 優, 遺伝子医学MOOK, (株)メディカルドゥ, Vol. 別冊, No. 細胞の3次元組織化-その最先端技術と材料技術, p. 354-358, 2014/02
  • Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo., Cui G,Hara T,Simmons S,Wagatsuma K,Abe A,Miyachi H,Kitano S,Ishii M,Tani-ichi S,Ikuta K, Proc Natl Acad Sci USA, Vol. 160, No. 2, p. 109-112, 2014/02
  • Dynamic Analysis of Histamine-Mediated Attenuation of Acetylcholine-Induced Sweating via GSK3 beta Activation, Saki Matsui,Hiroyuki Murota,Aya Takahashi,Lingli Yang,Jeong-Beom Lee,Kouta Omiya,Masato Ohmi,Junichi Kikuta,Masaru Ishii,Ichiro Katayama, JOURNAL OF INVESTIGATIVE DERMATOLOGY, NATURE PUBLISHING GROUP, Vol. 134, No. 2, p. 326-334, 2014/02
  • Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo, Guangwei Cui,Takahiro Hara,Szandor Simmons,Keisuke Wagatsuma,Akifumi Abe,Hitoshi Miyachi,Satsuki Kitano,Masaru Ishii,Shizue Tani-ichi,Koichi Ikuta, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 111, No. 5, p. 1915-1920, 2014/02
  • Dynamic Visualization of Dendritic Cell-Antigen Interactions in the Skin Following Transcutaneous Immunization, Teerawan Rattanapak,James C. Birchall,Katherine Young,Atsuko Kubo,Sayumi Fujimori,Masaru Ishii,Sarah Hook, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 9, No. 2, 2014/02
  • LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis, Takahiro Nakamura,Junji Hamuro,Mikiro Takaishi,Szandor Simmons,Kazuichi Maruyama,Andrea Zaffalon,Adam J. Bentley,Satoshi Kawasaki,Maho Nagata-Takaoka,Nigel J. Fullwood,Satoshi Itami,Shigetoshi Sano,Masaru Ishii,Yann Barrandon,Shigeru Kinoshita, JOURNAL OF CLINICAL INVESTIGATION, AMER SOC CLINICAL INVESTIGATION INC, Vol. 124, No. 1, p. 385-397, 2014/01
  • Intravital multiphoton microscopy for dissecting cellular dynamics in arthritic inflammation and bone destruction., Kikuta J,Ishii M, Methods in molecular biology (Clifton, N.J.), Vol. 1142, p. 1-10, 2014
  • Segmentation and Tracking Method of Cell Nuclei for Time-lapse Fluorescent Microscopy Images Based on Gaussian Mixture Model, Vol. 6, No. 3, p. 140-150, 2013/12
  • Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy, Teerawan Rattanapak,James Birchall,Katherine Young,Masaru Ishii,Igor Meglinski,Thomas Rades,Sarah Hook, JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE BV, Vol. 172, No. 3, p. 894-903, 2013/12
  • Cell Cycle-Dependent Rho GTPase Activity Dynamically Regulates Cancer Cell Motility and Invasion In Vivo, Yoshinori Kagawa,Shinji Matsumoto,Yuji Kamioka,Koshi Mimori,Yoko Naito,Taeko Ishii,Daisuke Okuzaki,Naohiro Nishida,Sakae Maeda,Atsushi Naito,Junichi Kikuta,Keizo Nishikawa,Junichi Nishimura,Naotsugu Haraguchi,Ichiro Takemasa,Tsunekazu Mizushima,Masataka Ikeda,Hirofumi Yamamoto,Mitsugu Sekimoto,Hideshi Ishii,Yuichiro Doki,Michiyuki Matsuda,Akira Kikuchi,Masaki Mori,Masaru Ishii, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 8, No. 12, 2013/12
  • [Dynamics of bone resorption analyzed by intravital imaging]., Kikuta J,Ishii M, Clinical calcium, Vol. 23, No. 11, p. 1627-1633, 2013/11
  • 【ストレスによる骨制御】骨吸収のダイナミクス ライブイメージング, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 23, No. 11, p. 1627-1633, 2013/10
  • Sphingosine-1-phosphate and chemokines in the control of osteoclast precursors migration visualized by intravital multiphoton microscopy, Junichi Kikuta,Atsuko Kubo,Masaru Ishii, Osteoimmunology: Interactions of the immune and skeletal systems, p. 73-79, 2013/10/01
  • 【骨粗鬆症領域の進歩】破骨細胞研究の最前線, 菊田 順一,石井 優, BIO Clinica, (株)北隆館, Vol. 28, No. 10, p. 911-916, 2013/09
  • 消化器研究における最新技術(第5回) 4Dイメージングによる消化器疾患への応用, 前田 栄,菊田 順一,石井 優, G.I.Research, (株)先端医学社, Vol. 21, No. 4, p. 368-374, 2013/08
  • 経時観測蛍光画像からのモーションヒストリーイメージを用いた細胞分裂の検出方法, 福田浩二郎,瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 2013/08
  • Global Data Associationによる経時観察画像における破骨前駆細胞の自動追跡手法, 尾野貴広,瀬尾茂人,間下以大,竹中要一,石井優,松田秀雄, 2013/07
  • Jumonji/Arid1b (Jarid1b) protein modulates human esophageal cancer cell growth., Yoshihiro Kano,Masamitsu Konno,Katsuya Ohta,Naotsugu Haraguchi,Shimpei Nishikawa,Yoshinori Kagawa,Atsushi Hamabe,Shinichiro Hasegawa,Hisataka Ogawa,Takahito Fukusumi,Yuko Noguchi,Miyuki Ozaki,Toshihiro Kudo,Daisuke Sakai,Taroh Satoh,Masaru Ishii,Eiichi Mizohata,Takeshi Inoue,Masaki Mori,Yuichiro Doki,Hideshi Ishii, Molecular and clinical oncology, Vol. 1, No. 4, p. 753-757, 2013/07
  • 生体多光子励起イメージングによる「骨形態・動態計測」研究の最前線, 石井 優,菊田 順一, 日本骨形態計測学会雑誌, 日本骨形態計測学会, Vol. 23, No. 1, p. S71-S71, 2013/06
  • 関節リウマチと骨軟骨代謝 バイオイメージングで解析する関節リウマチの骨破壊病態, 石井 優,菊田 順一, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 31回, p. 66-66, 2013/05
  • 生体多光子励起顕微鏡による生体骨組織内の血管透過性の評価とその制御機構の解明, 金子 雄,菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 31回, p. 104-104, 2013/05
  • Layer v cortical neurons require microglial support for survival during postnatal development, Masaki Ueno,Yuki Fujita,Tatsuhide Tanaka,Yuka Nakamura,Junichi Kikuta,Masaru Ishii,Toshihide Yamashita, Nature Neuroscience, Vol. 16, No. 5, p. 543-551, 2013/05
  • Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D, Junichi Kikuta,Shunsuke Kawamura,Fumie Okiji,Mai Shirazaki,Sadaoki Sakai,Hitoshi Saito,Masaru Ishii, Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, Vol. 110, No. 17, p. 7009-7013, 2013/04/23
  • 【骨代謝-「見えざる手」が制御する骨破壊と骨形成 リウマチ・骨粗鬆症の発症機構と分子標的治療】骨組織のin vivoイメージング, 菊田 順一,石井 優, 実験医学, (株)羊土社, Vol. 31, No. 6, p. 862-869, 2013/04
  • Depletion of JARID1B induces cellular senescence in human colorectal cancer., Katsuya Ohta,Naotsugu Haraguchi,Yoshihiro Kano,Yoshinori Kagawa,Masamitsu Konno,Shimpei Nishikawa,Atsushi Hamabe,Shinichiro Hasegawa,Hisataka Ogawa,Takahito Fukusumi,Mamoru Uemura,Junichi Nishimura,Taishi Hata,Ichiro Takemasa,Tsunekazu Mizushima,Yuko Noguchi,Miyuki Ozaki,Toshihiro Kudo,Daisuke Sakai,Taroh Satoh,Miwa Fukami,Masaru Ishii,Hirofumi Yamamoto,Yuichiro Doki,Masaki Mori,Hideshi Ishii, International journal of oncology, Vol. 42, No. 4, p. 1212-8, 2013/04
  • [Analysis of bone tissues by using fluorescent imaging]., Kikuta J,Ishii M, Clinical calcium, Vol. 23, No. 3, p. 355-360, 2013/03
  • 【骨評価法の進歩】蛍光イメージングによる骨評価, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 23, No. 3, p. 355-360, 2013/02
  • Osteoclast migration, differentiation and function: Novel therapeutic targets for rheumatic diseases, Junichi Kikuta,Masaru Ishii, Rheumatology (United Kingdom), Vol. 52, No. 2, p. 226-234, 2013/02
  • Dynamic visualization of RANKL and Th17-mediated osteoclast function., Junichi Kikuta,Yoh Wada,Toshiyuki Kowada,Ze Wang,Ge-Hong Sun-Wada,Issei Nishiyama,Shin Mizukami,Nobuhiko Maiya,Hisataka Yasuda,Atsushi Kumanogoh,Kazuya Kikuchi,Ronald N Germain,Masaru Ishii, The Journal of clinical investigation, Vol. 123, No. 2, p. 866-73, 2013/02
  • CognitionMaster: an object-based image analysis framework, Stephan Wienert,Daniel Heim,Manato Kotani,Bjoern Lindequist,Albrecht Stenzinger,Masaru Ishii,Peter Hufnagl,Michael Beil,Manfred Dietel,Carsten Denkert,Frederick Klauschen, DIAGNOSTIC PATHOLOGY, BIOMED CENTRAL LTD, Vol. 8, 2013/02
  • Systemic circulation and bone recruitment of osteoclast precursors tracked by using fluorescent imaging techniques, Manato Kotani,Junichi Kikuta,Frederick Klauschen,Takenao Chino,Yasuhiro Kobayashi,Hisataka Yasuda,Katsuto Tamai,Atsushi Miyawaki,Osami Kanagawa,Michio Tomura,Masaru Ishii, Journal of Immunology, Vol. 190, No. 2, p. 605-612, 2013/01/15
  • Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis., Ishii M,Kikuta J, Biochimica et biophysica acta, Vol. 1831, No. 1, p. 223-227, 2013/01
  • Dynamic live imaging of bone: Opening a new era with 'bone histodynametry', Masaru Ishii,Sayumi Fujimori,Takeshi Kaneko,Junichi Kikuta, Journal of Bone and Mineral Metabolism, Vol. 31, No. 5, p. 507-511, 2013
  • Orthovisual 骨のライブイメージング, 菊田 順一,石井 優, Arthritis-運動器疾患と炎症-, (株)メディカルレビュー社, Vol. 10, No. 3, p. 170-176, 2012/12
  • 多色蛍光イメージングによる経時観測データのための細胞追跡手法, 瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 2012/12
  • 生体イメージングクリニック, 菊田 順一,佐藤 康彦,石井 優, 日本免疫学会総会・学術集会記録, (NPO)日本免疫学会, Vol. 41, p. 223-223, 2012/11
  • 多色蛍光タイムラプスイメージングによる細胞周期観測データのための細胞自動追跡手法, 瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 2012/11
  • Automatic cell tracking for time-lapse fluorescent images of cell cycle, Shigeto Seno,Sakae Maeda,Tomohiro Mashita,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2012/10
  • A cell-tracking method for time-lapse multicolor fluorescent images, Shigeto Seno,Tomohiro Mashita,Yoichi Takenaka,Masaru Ishii,Hideo Matsuda, 2012/09
  • Recent Advances in Intravital Imaging of Dynamic Biological Systems, Junichi Kikuta,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 119, No. 3, p. 193-197, 2012/07
  • 【血管系のin vivoイメージング】生体骨組織内での破骨細胞動態イメージング, 小谷 真奈斗,菊田 順一,石井 優, 血管医学, (株)メディカルレビュー社, Vol. 13, No. 2, p. 137-143, 2012/06
  • Evolving FACS Technology FACSを応用した生体イメージング関連分子の解析, 賀川 義規,西川 恵三,前田 栄,菊田 順一,太田 勝也,西村 潤一,竹政 伊知朗,水島 恒和,池田 正孝,山本 浩文,関本 貢嗣,石井 秀始,土岐 祐一郎,森 正樹,石井 優, Cytometry Research, (一社)日本サイトメトリー学会, Vol. 22, No. Suppl., p. 46-46, 2012/06
  • 癌の細胞周期蛍光イメージングによる抗腫瘍薬の効果ポイントの可視化, 賀川 義規,前田 栄,太田 勝也,菊田 順一,西川 恵三,西村 潤一,竹政 伊知朗,水島 恒和,池田 正孝,山本 浩文,関本 貢嗣,石井 秀始,土岐 祐一郎,森 正樹,石井 優, Cytometry Research, (一社)日本サイトメトリー学会, Vol. 22, No. Suppl., p. 57-57, 2012/06
  • 【破骨細胞の機能とその異常】破骨細胞機能のイメージング, 菊田 順一,石井 優, 腎と骨代謝, (株)日本メディカルセンター, Vol. 25, No. 2, p. 107-113, 2012/04
  • The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice, Shigetomo Fukuhara,Szandor Simmons,Shunsuke Kawamura,Asuka Inoue,Yasuko Orba,Takeshi Tokudome,Yuji Sunden,Yuji Arai,Kazumasa Moriwaki,Junji Ishida,Akiyoshi Uemura,Hiroshi Kiyonari,Takaya Abe,Akiyoshi Fukamizu,Masanori Hirashima,Hirofumi Sawa,Junken Aoki,Masaru Ishii,Naoki Mochizuki, JOURNAL OF CLINICAL INVESTIGATION, AMER SOC CLINICAL INVESTIGATION INC, Vol. 122, No. 4, p. 1416-1426, 2012/04
  • How do contemporary imaging techniques contribute to basic and clinical rheumatology?, Masaru Ishii, ANNALS OF THE RHEUMATIC DISEASES, B M J PUBLISHING GROUP, Vol. 71, p. 67-69, 2012/04
  • 関節リウマチの病因・病態(2) 生体多光子励起イメージングによる成熟破骨細胞の動態解析, 菊田 順一,石井 優, 日本リウマチ学会総会・学術集会・国際リウマチシンポジウムプログラム・抄録集, (一社)日本リウマチ学会, Vol. 56回・21回, p. 341-341, 2012/03
  • Intestinal CX3C chemokine receptor 1(high) (CX(3)CR1(high)) myeloid cells prevent T-cell-dependent colitis, Hisako Kayama,Yoshiyasu Ueda,Yukihisa Sawa,Seong Gyu Jeon,Ji Su Ma,Ryu Okumura,Atsuko Kubo,Masaru Ishii,Taku Okazaki,Masaaki Murakami,Masahiro Yamamoto,Hideo Yagita,Kiyoshi Takeda, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 109, No. 13, p. 5010-5015, 2012/03
  • [Intravital imaging of cancer cell dynamics]., Kagawa Y,Maeda S,Mori M,Ishii M, Nihon Geka Gakkai zasshi, Japan Surgical Society (JSS), Vol. 113, No. 2, p. 171-176, 2012/03
  • 破骨細胞のイメージング, 菊田 順一,石井 優, リウマチ科, (有)科学評論社, Vol. 47, No. 2, p. 195-199, 2012/02
  • Use of intravital microscopy and in vitro chemotaxis assays to study the roles of sphingosine-1-phosphate in bone homeostasis, Taeko Ishii,Shunsuke Kawamura,Issei Nishiyama,Junichi Kikuta,Masaru Ishii, Methods in Molecular Biology, Vol. 874, p. 129-139, 2012
  • [Bone and calcium update; bone research update. Trafficking of osteoclast precursors visualized by intravital imaging technology]., Kotani M,Kikuta J,Ishii M, Clinical calcium, Vol. 21, No. 12, p. 85-91, 2011/12
  • 【骨・カルシウムUPDATE】骨代謝研究UPDATE 蛍光イメージング技術で観察する破骨前駆細胞のトラフィッキング, 小谷 真奈斗,菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 21, No. 12, p. 1835-1841, 2011/11
  • In Vivo Fluorescence Imaging of Bone-Resorbing Osteoclasts, Toshiyuki Kowada,Junichi Kikuta,Atsuko Kubo,Masaru Ishii,Hiroki Maeda,Shin Mizukami,Kazuya Kikuchi, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, Vol. 133, No. 44, p. 17772-17776, 2011/11
  • 【生きたままの姿を見る4Dイメージング-免疫・癌・脳神経の時空間的ダイナミクス】免疫・血液系の2光子励起イメージング"soft-wired network"の実体的解明, 菊田 順一,久保 厚子,島津 裕,石井 優, 実験医学, (株)羊土社, Vol. 29, No. 16, p. 2602-2606, 2011/10
  • 【分子イメージングの最先端】内科疾患の分子イメージング 骨・免疫系の細胞動態イメージング, 島津 裕,菊田 順一,久保 厚子,石井 優, 最新医学, (株)最新医学社, Vol. 66, No. 10, p. 2349-2353, 2011/10
  • [In vivo imaging of mature osteoclasts and RANKL signaling]., Kikuta J,Ishii M, Clinical calcium, Vol. 21, No. 8, p. 1181-1185, 2011/08
  • 【RANKLシグナルと骨病変】破骨細胞のイメージングとRANKLシグナル, 菊田 順一,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 21, No. 8, p. 1181-1185, 2011/07
  • 生体二光子励起顕微鏡による成熟破骨細胞の「機能」のイメージング, 菊田 順一,石井 優, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 29回, p. 197-197, 2011/07
  • S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis, Junichi Kikuta,Kaori Iwai,Yukihiko Saeki,Masaru Ishii, RHEUMATOLOGY INTERNATIONAL, SPRINGER HEIDELBERG, Vol. 31, No. 7, p. 967-969, 2011/07
  • ヒト破骨細胞の遊走を標的とした新規骨粗鬆症治療薬の開発と応用, 石井 優,菊田 順一,島津 裕,久保 厚子,岩井 香織,佐伯 行彦, 臨床薬理の進歩, (公財)臨床薬理研究振興財団, No. 32, p. 11-17, 2011/06
  • The role of sphingosine 1-phosphate in migration of osteoclast precursors; an application of intravital two-photon microscopy, Taeko Ishii,Yutaka Shimazu,Issei Nishiyama,Junichi Kikuta,Masaru Ishii, MOLECULES AND CELLS, KOREAN SOC MOLECULAR & CELLULAR BIOLOGY, Vol. 31, No. 5, p. 399-403, 2011/05
  • PDGFR alpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia, Katsuto Tamai,Takehiko Yamazaki,Takenao Chino,Masaru Ishii,Satoru Otsuru,Yasushi Kikuchi,Shin Iinuma,Kotaro Saga,Keisuke Nimura,Takashi Shimbo,Noriko Umegaki,Ichiro Katayama,Jun-ichi Miyazaki,Junji Takeda,John A. McGrath,Jouni Uitto,Yasufumi Kaneda, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 108, No. 16, p. 6609-6614, 2011/04
  • 【癌と生体イメージング】二光子励起顕微鏡による骨髄・骨転移性癌の生体イメージング, 小谷 真奈斗,菊田 順一,大畑 絵美,石井 優, Surgery Frontier, (株)メディカルレビュー社, Vol. 18, No. 1, p. 44-49, 2011/03
  • Intravital two-photon imaging: a versatile tool for dissecting the immune system, Taeko Ishii,Masaru Ishii, ANNALS OF THE RHEUMATIC DISEASES, B M J PUBLISHING GROUP, Vol. 70, p. I113-I115, 2011/03
  • [Encounter of cancer cells with bone. In vivo imaging of osteoclasts and their precursors in intact bone tissues]., Kikuta J,Kawamura S,Ishii M, Clinical calcium, Vol. 21, No. 3, p. 372-378, 2011/03
  • 【がんと骨の遭遇】骨組織のin vivoイメージングによる破骨細胞動態の解析, 菊田 順一,川村 俊輔,石井 優, Clinical Calcium, (株)医薬ジャーナル社, Vol. 21, No. 3, p. 372-378, 2011/02
  • 破骨細胞遊走の制御機構, 菊田 順一,小谷 真奈斗,石井 優, リウマチ科, (有)科学評論社, Vol. 45, No. 2, p. 209-214, 2011/02
  • S20-3 骨組織の生体多光子励起イメージングによる破骨細胞動態の解析(S20 New advances in allergy and immune regulation by imaging analysis,シンポジウム,第61回日本アレルギー学会秋季学術大会), 石井 優,菊田 順一, アレルギー, 一般社団法人 日本アレルギー学会, Vol. 60, No. 9, p. 1258-1258, 2011
  • Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo, Masaru Ishii,Junichi Kikuta,Yutaka Shimazu,Martin Meier-Schellersheim,Ronald N. Germain, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 207, No. 13, p. 2793-2798, 2010/12
  • ANG II inhibits insulin-mediated production of PI 3,4,5-trisphosphates via a Ca2+-dependent but PKC-independent pathway in the cardiomyocytes, Masashi Ikushima,Masaru Ishii,Mitsuru Ohishi,Koichi Yamamoto,Toshio Ogihara,Hiromi Rakugi,Yoshihisa Kurachi, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 299, No. 3, p. H680-H689, 2010/09
  • Close Up実験法(Series 205) 生体2光子励起顕微鏡による骨組織ライブイメージング, 島津 裕,石井 優, 実験医学, (株)羊土社, Vol. 28, No. 13, p. 2147-2153, 2010/08
  • 【歯と骨の炎症制御の新規標的】骨組織の生体イメージングによる骨吸収の新しい調節機構, 菊田 順一,石井 優, 炎症と免疫, (株)先端医学社, Vol. 18, No. 4, p. 349-354, 2010/06
  • Cellular modelling: experiments and simulation to develop a physiological model of G-protein control of muscarinic K+ channels in mammalian atrial cells, Shingo Murakami,Shingo Suzuki,Masaru Ishii,Atsushi Inanobe,Yoshihisa Kurachi, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, ROYAL SOC, Vol. 368, No. 1921, p. 2983-3000, 2010/06
  • A case of Mikulicz's disease with Th2-biased cytokine profile: possible feature discriminable from Sjogren's syndrome, Eriko Kudo-Tanaka,Shinichi Nakatsuka,Toru Hirano,Mari Kawai,Yoshinori Katada,Masato Matsushita,Shiro Ohshima,Masaru Ishii,Kunio Miyatake,Toshio Tanaka,Yukihiko Saeki, MODERN RHEUMATOLOGY, SPRINGER, Vol. 19, No. 6, p. 691-695, 2009/12
  • Visualization and Identification of IL-7 Producing Cells in Reporter Mice, Renata I. Mazzucchelli,Soren Warming,Scott M. Lawrence,Masaru Ishii,Mehrnoosh Abshari,A. Valance Washington,Lionel Feigenbaum,Andrew C. Warner,Davis J. Sims,Wen Qing Li,Julie A. Hixon,Daniel H. D. Gray,Benjamin E. Rich,Matthew Morrow,Miriam R. Anver,James Cherry,Dieter Naf,Lawrence R. Sternberg,Daniel W. McVicar,Andrew G. Farr,Ronald N. Germain,Keith Rogers,Nancy A. Jenkins,Neal G. Copeland,Scott K. Durum, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 4, No. 11, 2009/11
  • 骨粗鬆症 脂質メディエーターを標的とした新規の骨吸収性疾患治療薬の開発, 石井 優,菊田 順一,佐伯 行彦,Germain Ronald N., 日本リウマチ学会総会・学術集会・国際リウマチシンポジウムプログラム・抄録集, (一社)日本リウマチ学会, Vol. 53回・18回, p. 283-283, 2009/03
  • インフリキシマブ療法中、BOOPを発症したRAの2例, 田中 枝里子,松下 正人,菊田 順一,石井 優,大島 至郎,佐伯 行彦, 日本リウマチ学会総会・学術集会・国際リウマチシンポジウムプログラム・抄録集, (一社)日本リウマチ学会, Vol. 53回・18回, p. 311-311, 2009/03
  • TNF阻害療法(インフリキシマブおよびエタネルセプト)無効でIL-6阻害療法が著功した難治性関節リウマチの3症例, 菊田 順一,田中 枝里子,石井 優,松下 正人,大島 至郎,佐伯 行彦, 日本リウマチ学会総会・学術集会・国際リウマチシンポジウムプログラム・抄録集, (一社)日本リウマチ学会, Vol. 53回・18回, p. 389-389, 2009/03
  • Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis, Masaru Ishii,Jackson G. Egen,Frederick Klauschen,Martin Meier-Schellersheim,Yukihiko Saeki,Jean Vacher,Richard L. Proia,Ronald N. Germain, NATURE, NATURE PUBLISHING GROUP, Vol. 458, No. 7237, p. 524-U8, 2009/03
  • MS11-6 骨髄線維症を認めた混合性結合組織病の一症例(MS11 自己免疫疾患・リウマチ性疾患・免疫不全症,ミニシンポジウム11,第21回日本アレルギー学会春季臨床大会), 山中 隆夫,原田 芳徳,石井 泰子,菊田 順一,田中 枝里子,石井 優,松下 正人,大島 至郎,佐伯 行彦,片田 圭宣, アレルギー, 一般社団法人 日本アレルギー学会, Vol. 58, No. 3, p. 380-380, 2009
  • Quantifying cellular interaction dynamics in 3D fluorescence microscopy data, Frederick Klauschen,Masaru Ishii,Hai Qi,Marc Bajenoff,Jackson G. Egen,Ronald N. Germain,Martin Meier-Schellersheim, NATURE PROTOCOLS, NATURE PUBLISHING GROUP, Vol. 4, No. 9, p. 1305-1312, 2009
  • [System biology]., Ishii M,Kurachi Y, Nihon yakurigaku zasshi. Folia pharmacologica Japonica, Vol. 126, No. 2, p. 117-120, 2005/08
  • カルベジロールがATP感受性カリウムチャネルとG蛋白質制御カリウムチャネルのポアを阻害する, 菊田 順一,石井 優,岸本 健太郎,倉智 嘉久, 日本生理学雑誌, (一社)日本生理学会, Vol. 67, No. 2, p. 77-78, 2005/02
  • Investigation of the block and facilitation effects by nifekalant in a HERG channel, Y Hosaka,M Yamada,M Ishii,Y Kurachi, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, No. 6, p. 235P-235P, 2005
  • 内耳蝸牛側壁における内向き整流K+チャネルKir5.1の局在と内耳機能との関連, 日比野 浩,東 佳代子,藤田 秋一,岩井 香織,石井 優,倉智 嘉久, 日本生理学雑誌, (一社)日本生理学会, Vol. 66, No. 2, p. 65-65, 2004/02
  • 網膜における内向き整流性カリウムチャネルサブユニットKir5.1の局在 Kir4.1との比較, 石井 優,藤田 秋一,岩井 香織,東 佳代子,日比野 浩,倉智 嘉久, 日本生理学雑誌, (一社)日本生理学会, Vol. 66, No. 2, p. 65-66, 2004/02
  • カルベジロールがATP感受性カリウムチャネルとG蛋白質制御カリウムチャネルのポアを阻害する, 菊田 順一,岸本 健太郎,石井 優,倉智 嘉久, 日本薬理学雑誌, (公社)日本薬理学会, Vol. 123, No. 2, p. 51P-51P, 2004/02
  • Assays of RGS protein modulation by phosphatidylinositides and calmodulin, M Ishii,Y Kurachi, REGULATORS OF G-PROTEIN SIGNALING, PART A, ELSEVIER ACADEMIC PRESS INC, Vol. 389, p. 105-118, 2004
  • Assays of RGS protein modulation by phosphatidylinositides and calmodulin, M Ishii,Y Kurachi, REGULATORS OF G-PROTEIN SIGNALING, PART A, ELSEVIER ACADEMIC PRESS INC, Vol. 389, p. 105-118, 2004
  • Cell signal control of the G protein-gated potassium channel and its subcellular localization, Y Kurachi,M Ishii, JOURNAL OF PHYSIOLOGY-LONDON, BLACKWELL PUBLISHING LTD, Vol. 554, No. 2, p. 285-294, 2004/01
  • Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall, H Hibino,K Higashi,A Fujita,K Iwai,M Ishii,Y Kurachi, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 122P-122P, 2004
  • Physiological actions of regulators of G-protein signaling (RGS) proteins, Masaru Ishii,Yoshihisa Kurachi, Life Sciences, Elsevier Inc., Vol. 74, No. 2-3, p. 163-171, 2003/12/05
  • Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina., Ishii M,Fujita A,Iwai K,Kusaka S,Higashi K,Inanobe A,Hibino H,Kurachi Y, 2003/07
  • Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders, Masaru Ishii,Norihiko Yamaguchi,Shiro Ohshima,Taeko Ishii,Kiyoshi L. Mori,Hiroshi Kimura,Tsuneo Morishima,Ichiro Kawase,Yukihiko Saeki, Internal Medicine, Japanese Society of Internal Medicine, Vol. 42, No. 3, p. 250-254, 2003/03/01
  • Characteristics of electromagnetic return-stroke models, Yoshihiro Baba,Masaru Ishii, IEEE Transactions on Electromagnetic Compatibility, Vol. 45, No. 1, p. 129-135, 2003/02
  • A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5, T Ishii,T Tatekawa,M Koseto,M Ishii,H Kobayashi,M Koike,T Fujii,Y Saeki, EUROPEAN JOURNAL OF HAEMATOLOGY, BLACKWELL MUNKSGAARD, Vol. 70, No. 2, p. 115-118, 2003/02
  • Cardiac conduction and arrhythmia: Insights from Nkx2.5 mutations in mouse and humans, Patrick Y. Jay,Charles I. Berul,Makoto Tanaka,Masao Ishii,Yoshihisa Kurachi,Seigo Izumo,Gourdie,Markwald,Thompson,Burch, Novartis Foundation Symposium, Vol. 250, p. 227-241, 2003
  • The 14-3-3 protein as a novel regulator of ion channel localisation, M Ishii,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 545, No. 1, p. 2-2, 2002/11
  • Idiopathic portal hypertension in a systemic sclerosis patient heterozygous for factor V Leiden mutation, Ishii M,Katada Y, 2002/11
  • PIPS inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel, M Ishii,A Inanobe,Y Kurachi, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 99, No. 7, p. 4325-4330, 2002/04
  • A mouse model of congenital heart disease: Cardiac arrhythmias and atrial septal defect caused by haploin sufficiency of the cardiac transcription factor Csx/Nkx2.5, M Tanaka,CI Berul,M Ishii,PY Jay,H Wakimoto,P Douglas,N Yamasaki,T Kawamoto,J Gehrmann,CT Maguire,M Schinke,CE Seidman,JG Seidman,Y Kurachi,S Izumo, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, Vol. 67, p. 317-325, 2002
  • A possible mechanism of NK cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) in a patient with chronic active Epstein-Barr virus infection (CAEBV) and severe hypersensitivity to mosquito bites (SHMB), Shiro Ohshima,Masaru Ishii,Hideo Asada,Toyoshi Tatekawa,Norihiko Yamaguchi,Hideyuki Kobayashi,Taeko Ishii,Toru Mima,Ichiro Kawase,Yukihiko Saeki, Internal Medicine, Japanese Society of Internal Medicine, Vol. 41, No. 8, p. 651-656, 2002
  • Ca2+ elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart, M Ishii,A Inanobe,S Fujita,YA Makino,Y Hosoya,Y Kurachi, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 89, No. 11, p. 1045-1050, 2001/11
  • Interaction between the RGS domain of RGS4 with G protein α subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel, A. Inanobe,S. Fujita,Y. Makino,K. Matsushita,M. Ishii,M. Chachin,Y. Kurachi, Journal of Physiology, Vol. 535, No. 1, p. 133-143, 2001/08/15
  • Possible association of "shrinking lung" and anti-Ro/SSA antibody, M Ishii,H Uda,T Yamagami,Y Katada, ARTHRITIS AND RHEUMATISM, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 11, p. 2612-2613, 2000/11
  • Characterization of lightning current measured on tall structures, Masaru Ishii,Yoshihiro Baba, SAE Technical Papers, 1999
  • Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90, Y Horio,H Hibino,A Inanobe,M Yamada,M Ishii,Y Tada,E Satoh,Y Hata,Y Takai,Y Kurachi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 20, p. 12885-12888, 1997/05
  • Expression and clustered distribution of an inwardly rectifying potassium channel, K(AB)-2/Kir4.1, on mammalian retinal Muller cell membrane: Their regulation by insulin and laminin signals, Masaru Ishii,Yoshiyuki Horio,Yoshihiko Tada,Hiroshi Hibino,Atsushi Inanobe,Minoru Ito,Mitsuhiko Yamada,Takahiro Gotow,Yasuo Uchiyama,Yoshihisa Kurachi, Journal of Neuroscience, Vol. 17, No. 20, p. 7725-7735, 1997

Misc.

  • 骨組織の生体イメージング—Intravital imaging of bone tissues—特集 新組織学シリーズ(4)骨・軟骨 ; 骨・軟骨組織の構造と細胞分化・機能, 鎗 伸弥,菊田 順一,石井 優, 生体の科学, 金原一郎記念医学医療振興財団, Vol. 74, No. 6, p. 540-543, 2023
  • Arthritis-associated osteoclastogenic macrophage, AtoM, as a key player in pathological bone erosion, Tomoya Agemura,Tetsuo Hasegawa,Shinya Yari,Junichi Kikuta,Masaru Ishii, Inflammation and Regeneration, Vol. 42, No. 1, 2022/12
  • Arthritis-associated osteoclastogenic macrophages (AtoMs) participate in pathological bone erosion in rheumatoid arthritis, Tomoya Agemura,Tetsuo Hasegawa,Shinya Yari,Junichi Kikuta,Masaru Ishii, Immunological Medicine, Vol. 45, No. 1, p. 22-26, 2022
  • How is Bone Homeostasis Maintained? Dynamic Regulatory Mechanism by Cells with Opposite Functions, 鎗伸弥,菊田順一,石井優, 生物物理(Web), Vol. 60, No. 4, 2020
  • Direct cell-cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo., 古家雅之,古家雅之,古家雅之,菊田順一,瀬尾茂人,前田拓樹,柏井将文,柏井将文,海渡貴司,橋本国彦,橋本国彦,松田秀雄,菊地和也,石井優,吉川秀樹,吉川秀樹, Journal of Spine Research (Web), Vol. 11, No. 3, 2020
  • 病理形態学の新技術・多光子励起顕微鏡を用いた病理診断, 松井崇浩,石井優, 病理と臨床, Vol. 37, No. 7, p. 609-616, 2019/07
  • High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node, Szandor Simmons,Naoko Sasaki,Eiji Umemoto,Yutaka Uchida,Shigetomo Fukuhara,Yusuke Kitazawa,Michiyo Okudaira,Asuka Inoue,Kazuo Tohya,Keita Aoi,Junken Aoki,Naoki Mochizuki,Kenjiro Matsuno,Kiyoshi Takeda,Wolfgang M. Kuebler,Masayuki Miyasaka,Masaru Ishii, FASEB JOURNAL, WILEY, Vol. 33, 2019/04
  • 生体骨イメージングによる生物学的製剤のin vivo作用機序の解明, 菊田 順一,松浦 良信,平野 亨,熊ノ郷 淳,石井 優, 日本臨床免疫学会総会プログラム・抄録集, (一社)日本臨床免疫学会, Vol. 46回, p. 104-104, 2018/11
  • 生体骨イメージングによる生物学的製剤のin vivo作用機序の解明, 菊田 順一,松浦 良信,平野 亨,熊ノ郷 淳,石井 優, 日本臨床免疫学会総会プログラム・抄録集, (一社)日本臨床免疫学会, Vol. 46回, p. 122-122, 2018/11
  • The effects of biologic agents on osteoclast lineage cells evaluated by intravital two-photon microscopy, Yoshinobu Matsuura,Junichi Kikuta,Masaru Ishii, CYTOKINE, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 100, p. 111-112, 2017/12
  • Global Data Associationを用いたアメーバ状細胞の追跡手法 (情報論的学習理論と機械学習), 間下 以大,深野 淳,白崎 舞,菊田 順一,石井 優,竹村 治雄, 電子情報通信学会技術研究報告 = IEICE technical report : 信学技報, 電子情報通信学会, Vol. 117, No. 110, p. 19-24, 2017/06/23
  • Global Data Associationを用いたアメーバ状細胞の追跡手法 (ニューロコンピューティング), 間下 以大,深野 淳,白崎 舞,菊田 順一,石井 優,竹村 治雄, 電子情報通信学会技術研究報告 = IEICE technical report : 信学技報, 電子情報通信学会, Vol. 117, No. 109, p. 69-74, 2017/06/23
  • 細胞接着・接触を介した肝臓における糖代謝制御機構の解明, 宮地 康高,土屋 恭一郎,柴 久美子,森 健太郎,出牛 三千代,大坂 瑞子,吉田 雅幸,菊田 順一,石井 優,小川 佳宏, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 1, p. 380-380, 2017/04
  • 細胞間物理的相互作用に注目した肥満に伴う肝臓の糖代謝異常の分子機構, 宮地 康高,土屋 恭一郎,山口 忍,柴 久美子,森 健太郎,出牛 三千代,大坂 瑞子,吉田 雅幸,菊田 順一,石井 優,小川 佳宏, 糖尿病, (一社)日本糖尿病学会, Vol. 60, No. Suppl.1, p. S-491, 2017/04
  • 細胞接着と接触を介した肥満に伴う糖代謝異常の惹起機構, 宮地 康高,土屋 恭一郎,柴 久美子,森 健太郎,出牛 三千代,大坂 瑞子,吉田 雅幸,菊田 順一,石井 優,小川 佳宏, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 92, No. 3, p. 889-889, 2017/01
  • 二光子励起生体イメージングを用いた破骨細胞・骨芽細胞コミュニケーションの解明, 古家雅之,古家雅之,古家雅之,菊田順一,瀬尾茂人,前田拓樹,柏井将文,海渡貴司,菊地和也,松田秀雄,吉川秀樹,石井優, 日本整形外科学会雑誌, Vol. 91, No. 8, 2017
  • 生体骨イメージングで捉える骨代謝 (特集 骨粗鬆症治療における新しい接点), 菊田 順一,古家 雅之,石井 優, 骨粗鬆症治療 = Journal of osteoporotic medicine, 先端医学社, Vol. 16, No. 1, p. 52-55,7-8, 2017/01
  • Osteoclast, Vol. 259, No. 5, p. 446-452, 2016/10/29
  • 肝臓における細胞接触・接着を介した新たな糖代謝制御機構の解明, 宮地 康高,土屋 恭一郎,柴 久美子,森 健太郎,出牛 三千代,大坂 瑞子,吉田 雅幸,菊田 順一,石井 優,小川 佳宏, 肥満研究, (一社)日本肥満学会, Vol. 22, No. Suppl., p. 193-193, 2016/09
  • Implications of Spns2-deficiency on S1P-driven lymphocytes egress, HEV-integrity and immunity, S. Simmons,N. Sasaki,E. Umemoto,N. Yoshizumi,S. Fukuhara,Y. Kitazawa,M. Okudaira,A. Inoue,D. Motooka,S. Nakamura,T. Iida,J. Aoki,N. Mochizuki,K. Matsuno,K. Takeda,M. Miyasaka,M. Ishii, EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Vol. 46, p. 267-267, 2016/08
  • 最新用語解説 基礎(第52回)生体イメージング, 菊田 順一,石井 優, 骨粗鬆症治療 = Journal of osteoporotic medicine, 先端医学社, Vol. 15, No. 1, p. 59-63,5-7, 2016/06
  • Physical Cell-Cell Interaction Regulates Hepatic Glucose Metabolism in Mice, Kyoichiro Tsuchiya,Yasutaka Miyachi,Chikara Komiya,Kumiko Shiba,Noriko Shimazu,Shinobu Yamaguchi,Mizuko Osaka,Masayuki Yoshida,Koji Inoue,Kenjiro Wake,Yuta Sato,Junichi Kikuta,Masaru Ishii,Yoshihiro Ogawa, DIABETES, AMER DIABETES ASSOC, Vol. 65, p. A462-A462, 2016/06
  • Intravital imaging of immune cells, Vol. 257, No. 6, p. 727-731, 2016/05/07
  • Imaging Analysis of Macrophage Dynamics During Chronic Inflammation, Vol. 71, No. 5, p. 1026-1030, 2016/05
  • 血管生物学における生体イメージング技術 (特集 再生医学と血管), 菊田 順一,石井 優, 血管医学, メディカルレビュー社, Vol. 17, No. 1, p. 41-45, 2016/03
  • In vivoイメージング : 骨関節疾患評価の新たな取り組み (特集 骨関節疾患の画像評価), 菊田 順一,石井 優, Rheumatology clinical research : journal of rheumatology clinical research, 先端医学社, Vol. 4, No. 3, p. 180-185, 2015/12
  • Intravital imaging of bone tissues by multiphoton microscopy, Vol. 64, No. 2, p. 194-199, 2015/08
  • 最新用語解説 基礎(第50回)S1P, 菊田 順一,石井 優, 骨粗鬆症治療 = Journal of osteoporotic medicine, 先端医学社, Vol. 14, No. 2, p. 151-154, 2015/08
  • 4D imaging of bone tissue, Vol. 5, No. 2, p. 132-135, 2015/05
  • PAMPs受容体研究の最前線 スフィンゴシン1リン酸受容体とB細胞受容体との会合にMD-1は影響を及ぼす(PAMPs receptor update MD-1 influences a binding between S1P1 and BCR), 高村 祥子,山川 奈津子,谷村 奈津子,柴田 琢磨,鈴木 一博,菊田 順一,石井 優,三宅 健介, 日本細菌学雑誌, 日本細菌学会, Vol. 70, No. 1, p. 128-128, 2015/02
  • 骨代謝のin vivoイメージング (内分泌) -- (基礎分野での進歩), 菊田 順一,石井 優, Annual review. 糖尿病・代謝・内分泌, 中外医学社, p. 152-159, 2015
  • リウマチ治療薬の効果予測及び効果判定を目的としたIL-6受容体抗体の125I標識及び体内動態の観察, 金井 泰和,菊田 順一,渡部 直史,仲 定宏,礒橋 佳也子,加藤 弘樹,巽 光朗,阿部 浩司,下瀬川 恵久,石井 優,畑澤 順, 核医学, (一社)日本核医学会, Vol. 51, No. 3, p. 336-336, 2014/09
  • 眼で見るBone Biology(第38回)S1P/S1P受容体と骨粗鬆症, 菊田 順一,石井 優, 骨粗鬆症治療 = Journal of osteoporotic medicine, 先端医学社, Vol. 13, No. 2, p. 93-96, 2014/08
  • 4D imaging, Vol. 57, No. 7, p. 921-926, 2014/06
  • PS-083-3 細胞周期の可視化によるIFN/5-FU併用療法の作用機序解明(PS-083 肝 基礎-3,ポスターセッション,第114回日本外科学会定期学術集会), 山下 雅史,和田 浩志,富丸 義人,前田 栄,谷崎 慶子,山中 千尋,石井 優,永野 浩昭,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 115, No. 2, p. 740-740, 2014/03/05
  • A Bone-Marrow Space Segmentation Method using Graph-Cuts, Jun Usami,Hironori Shigeta,Tomohiro Mashita,Yoshihiro Kuroda,Junichi Kikuta,Shigeto Senoo,Masaru Ishii,Hideo Matsuda,Haruo Takemura, IPSJ SIG Notes, Information Processing Society of Japan (IPSJ), Vol. 2014, No. 17, p. 1-6, 2014/02/24
  • Dynamic analysis of short-term effects of bisphosphonates by using intravital two-photon microscopy, Junichi Kikuta,Mai Shirazaki,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, Vol. 29, p. S193-S193, 2014/02
  • EBI2 guides osteoclast precursors to endosteal niches and regulates bone mass homeostasis., Erin Nevius,Mark Horowitz,Masaru Ishii,Joao Pereira, JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, Vol. 29, p. S45-S45, 2014/02
  • 生体二光子励起イメージングによる骨芽細胞・破骨細胞カップリングの可視化, 古家雅之,古家雅之,菊田順一,白崎舞,柏井将文,牧野孝洋,海渡貴司,岩崎幹季,石井優,吉川秀樹, 日本整形外科学会雑誌, Vol. 88, No. 8, 2014
  • Intravital Imaging of Macrophage Dynamics in Bone Resorption and Chronic Inflammation, Vol. 33, No. 12, p. 1267-1271, 2014
  • 生体イメージングでとらえた細胞周期と癌細胞浸潤の関係, 賀川義規,賀川義規,賀川義規,山本浩文,松本慎司,上岡裕治,奥崎大介,内藤陽子,前田栄,前田栄,内藤敦,内藤敦,三森功士,石井秀始,松田道行,菊池章,土岐祐一郎,石井優,森正樹, 日本がん転移学会学術集会・総会プログラム抄録集, Vol. 23rd, 2014
  • Development of an in vitro culture method for stepwise differentiation of mouse embryonic stem cells and induced pluripotent stem cells into mature osteoclasts, Keizo Nishikawa,Yoriko Iwamoto,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 116P-116P, 2014
  • イメージング技術の移植への応用 移植腎臓live imaging:functional MRIとmultiphoton microscopy 2つのmodality, 貝森 淳哉,市丸 直嗣,猪阪 善隆,楽木 宏実,石井 優,小林 英司,高原 史郎, 移植, (一社)日本移植学会, Vol. 48, No. 総会臨時, p. 239-239, 2013/08
  • Hypomelanotic macules in tuberous sclerosis complex is linked to Th17 cell infiltration with possible impairment of cytoplasmic autophagy via mTOR pathway, Y. Kotobuki,L. Yang,M. Wataya-Kaneda,D. Tsuruta,A. Tanemura,M. Tanaka,H. Murota,M. Ishii,I. Katayama, JOURNAL OF INVESTIGATIVE DERMATOLOGY, NATURE PUBLISHING GROUP, Vol. 133, p. S241-S241, 2013/05
  • Histamine attenuates acetylcholine-mediated sweating by inactivating GSK3 beta via H1-receptor mediated pathway, S. Matsui,H. Murota,Y. Lingli,K. Omiya,M. Ohmi,J. Kikuta,M. Ishii,I. Katayama, JOURNAL OF INVESTIGATIVE DERMATOLOGY, NATURE PUBLISHING GROUP, Vol. 133, p. S105-S105, 2013/05
  • Integrin alpha 9 on lymphatic endothelial cell at draining lymph node regulates lymphocyte egress via controlling S1P secretion during inflammation (P5114), Koyu Ito,Junko Morimoto,Akio Kihara,Szandor Simmons,Masaru Ishii,Toshimitsu Uede, JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 190, 2013/05
  • Evaluation Method Based on Graph Cut For Barrier Permeation in Bone Tissues, Vol. 2013, No. 3, p. 1-6, 2013/03/14
  • PS-348-2 インターフェロン(IFN)レセプターの遺伝子導入及び細胞周期の可視化によるIFN/5-FU併用療法の機序解明に関する検討(PS ポスターセッション,第113回日本外科学会定期学術集会), 前田 栄,和田 浩志,濱 直樹,賀川 義規,秋田 裕史,川本 弘一,小林 省吾,江口 英利,梅下 浩司,石井 優,永野 浩昭,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, p. 1008-1008, 2013/03/05
  • 消化器癌の生物学的動態を制御するエピジェネティクス, 太田勝也,原口直紹,賀川義規,加納義浩,今野雅允,植村守,西村潤一,竹政伊知朗,水島恒和,山本浩文,石井優,石井秀始,土岐祐一郎,森正樹, 日本外科学会雑誌, Vol. 114, No. 臨増2, p. 402-402, 2013/03/05
  • YT-5-3(YRA) 消化器癌の生物学的動態を制御するエピジェネティクス(YT Young Researcher Award & Traveler's Grant,第113回日本外科学会定期学術集会), 太田 勝也,原口 直紹,賀川 義規,加納 義浩,今野 雅允,植村 守,西村 潤一,竹政 伊知朗,水島 恒和,山本 浩文,石井 優,石井 秀始,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, p. 402-402, 2013/03/05
  • VF-022-2 生体イメージングによる細胞周期と浸潤関連分子の同定と臨床応用(VF ビデオフォーラム,第113回日本外科学会定期学術集会), 賀川 義規,前田 栄,深見 美和,菊田 順一,内藤 敦,西川 恵三,太田 勝也,藤森 さゆ美,Simmons Szandor,石井 泰子,植村 守,原口 直紹,西村 潤一,畑 泰司,竹政 伊知朗,水島 恒和,山本 浩文,石井 秀始,土岐 祐一郎,石井 優,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, p. 440-440, 2013/03/05
  • YT-5-3(YRA) 消化器癌の生物学的動態を制御するエピジェネティクス(YT Young Researcher Award & Traveler's Grant,第113回日本外科学会定期学術集会), 太田 勝也,原口 直紹,賀川 義規,加納 義浩,今野 雅允,植村 守,西村 潤一,竹政 伊知朗,水島 恒和,山本 浩文,石井 優,石井 秀始,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, 2013/03/05
  • VF-022-2 生体イメージングによる細胞周期と浸潤関連分子の同定と臨床応用(VF ビデオフォーラム,第113回日本外科学会定期学術集会), 賀川 義規,前田 栄,深見 美和,菊田 順一,内藤 敦,西川 恵三,太田 勝也,藤森 さゆ美,Simmons Szandor,石井 泰子,植村 守,原口 直紹,西村 潤一,畑 泰司,竹政 伊知朗,水島 恒和,山本 浩文,石井 秀始,土岐 祐一郎,石井 優,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 114, No. 2, p. 440-440, 2013/03/05
  • 混合正規分布モデルを用いた経時観測蛍光画像からの細胞核の検出と追跡手法, 瀬尾茂人,間下以大,前田栄,竹中要一,石井優,松田秀雄, 研究報告数理モデル化と問題解決（MPS）, Vol. 2013, No. 5, p. 1-6, 2013/02/20
  • S1P-mediated Osteoclast Precursor Monocyte Migration Is a Critical Point of Control in Antibone-resorptive Action of Active Vitamin D, Junichi Kikuta,Junichi Kikuta,Fumie Okiji,Mai Shirazaki,Sadaoki Sakai,Hitoshi Saito,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, WILEY-BLACKWELL, Vol. 28, 2013/02
  • Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis, Masaru Ishii,Junichi Kikuta, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ELSEVIER SCIENCE BV, Vol. 1831, No. 1, p. 223-227, 2013/01
  • Dynamic in Vivo Imaging of Th17-Mediated Osteoclastic Bone Resorption in Live Bones by Using Intravital Multiphoton Microscopy, Junichi Kikuta,Masaru Ishii, ARTHRITIS AND RHEUMATISM, WILEY-BLACKWELL, Vol. 64, No. 10, p. S311-S312, 2012/10
  • Dynamic behaviors of osteoclasts and immune cells visualized by fluorescent imaging, Vol. 242, No. 9, p. 727-733, 2012/09/01
  • 細胞周期制御の新展開 新規細胞周期依存性RhoGAP「Celmobilin」によるヒト癌細胞の遊走と浸潤の制御(New aspect of cell cycle research and cancer A novel cell cycle-associated RhoGAP, Celmobilin, regulates cancer cell motility and invasion in human), 賀川 義規,西川 恵三,前田 栄,松本 真司,奥崎 大介,三森 功士,山本 浩文,関本 貢嗣,菊池 章,石井 秀始,土岐 祐一郎,森 正樹,石井 優, 日本癌学会総会記事, 日本癌学会, Vol. 71回, p. 94-94, 2012/08
  • DYNAMIC IN VIVO IMAGING OF TH17-MEDIATED CONTROL OF OSTEOCLAST FUNCTION IN LIVE BONES BY USING INTRAVITAL MULTIPHOTON MICROSCOPY, J. Kikuta,M. Ishii, ANNALS OF THE RHEUMATIC DISEASES, BMJ PUBLISHING GROUP, Vol. 71, p. 66-66, 2012/06
  • SF-028-1 細胞周期の可視化によるインターフェロン/5-FU併用療法の作用機序解明を目指した基礎的検討(SF-028 サージカルフォーラム(28)肝 基礎-4,第112回日本外科学会定期学術集会), 前田 栄,和田 浩志,永野 浩昭,賀川 義規,西川 恵三,川本 弘一,小林 省吾,丸橋 繁,江口 英利,種村 匡弘,梅下 浩司,石井 優,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 113, No. 2, p. 321-321, 2012/03/05
  • Migratory control of bone-resorbing osteoclasts visualized by intravital multiphoton microcopy, Masaru Ishii,Junichi Kikuta, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 23P-23P, 2012
  • Dynamic in vivo imaging of bone-resorptive functions of mature osteoclasts in live bones by using intravital multiphoton microscopy, Junichi Kikuta,Yoh Wada,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 70P-70P, 2012
  • 癌の生体イメージング―細胞周期と細胞可動性について―, 賀川義規,石井秀始,竹政伊知朗,水島恒和,池田正孝,山本浩文,関本貢嗣,土岐祐一郎,石井優,森正樹, 日本消化器外科学会雑誌(Web), Vol. 45, No. Supplement1, 2012
  • SF-035-4 二光子励起顕微鏡を用いたがん細胞の生体イメージング(SF-035 サージカルフォーラム(35)大腸:その他-1,第111回日本外科学会定期学術集会), 賀川 義規,石井 秀始,石井 泰子,久保 厚子,鈴木 陽三,宮崎 進,川村 俊輔,小谷 真奈斗,藤森 さゆ美,島津 裕,菊田 順一,竹政 伊知朗,水島 恒和,池田 正孝,山本 浩文,坂上-沢野 朝子,宮脇 敦史,石井 優,関本 貢嗣,土岐 祐一郎,森 正樹, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 112, No. 1, p. 379-379, 2011/05/25
  • 大腸癌の分子生物学 生体イメージングによる癌の可視化, 賀川 義規,森 正樹,石井 優, 大腸癌frontier, メディカルレビュー社, Vol. 4, No. 1, p. 91-95, 2011/03
  • Analysis of bone tissues by using fluorescent imaging, Cell technology, Vol. 30, No. 3, p. 277-282, 2011
  • Analysis of the mechanisms of bone metabolism using intravital imaging, Bio industry, Vol. 28, No. 1, p. 23-27, 2011/01
  • 骨組織のライブイメージングによる破骨前駆細胞の動態解析 (特集 分子イメージングの最先端), 小谷 真奈斗,菊田 順一,石井 優, PET journal, 寺田国際事務所先端医療技術研究所, No. 16, p. 17-19, 2011
  • Chemokine-mediated migration control of bone cells visualized by intravital multiphoton bone imaging, Masaru Ishii,Junichi Kikuta,Atsuko Kubo,Yutaka Shimazu, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 57P-57P, 2011
  • Dynamic in vivo imaging of differentiation and function of osteoclasts in live bones by using intravital two-photon microscopy, Junichi Kikuta,Issei Nishiyama,Atsuko Kubo,Yutaka Shimazu,Yoh Wada,Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 93P-93P, 2011
  • スフィンゴシン1リン酸の破骨細胞分化に及ぼす影響, 天野 均,唐川 亜希子,菊田 順一,石井 優,山田 庄司, 日本骨代謝学会学術集会プログラム抄録集, (一社)日本骨代謝学会, Vol. 28回, p. 167-167, 2010/07
  • Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis (vol 458, pg 524, 2009), Masaru Ishii,Jackson G. Egen,Frederick Klauschen,Martin Meier-Schellersheim,Yukihiko Saeki,Jean Vacher,Richard L. Proia,Ronald N. Germain, NATURE, NATURE PUBLISHING GROUP, Vol. 465, No. 7300, 2010/06
  • Automated cell tracking and interaction analysis in intra-vital two-photon microscopy image data, Frederick Klauschen,Martin Meier-Schellersheim,Judith Mandl,Hai Qi,Masaru Ishii,Manfred Dietel,Ronald N. Germain,Carsten Denkert, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 70, 2010/04
  • Chemokine and lipid mediator-mediated control of osteoclast migration visualized by in vivo bone imaging: A novel point of regulation for bone homeostasis, Masaru Ishii, BONE, ELSEVIER SCIENCE INC, Vol. 46, p. S10-S11, 2010/03
  • Chemokine-mediated migration control of osteoclast precursors visualized by intravital bone imaging: A novel therapeutic target for bone diseases, Masaru Ishii, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 48P-48P, 2010
  • 重度の血球貪食症候群を発症したが、ステロイド・パルス療法が著効した関節リウマチの1例, 松下 正人,菊田 順一,田中 枝里子,石井 優,大島 至郎,山中 隆夫,原田 芳徳,石井 泰子,片田 圭宣,佐伯 行彦, 日本リウマチ学会総会・学術集会・国際リウマチシンポジウムプログラム・抄録集, (一社)日本リウマチ学会, Vol. 53回・18回, p. 317-317, 2009/03
  • 破骨細胞の遊走・位置決めの機構の解明とこれをターゲットとした新しい骨粗鬆症治療薬の開発 (第16回(平成20年度) 財団法人骨粗鬆症財団 研究助成に関する成果報告), 石井 優,岩井 香織,菊田 順一, オステオポローシスジャパン, ライフサイエンス出版, Vol. 17, No. 4, p. 689-691, 2009
  • Osteoclast cell fusion: mechanisms and molecules, Masaru Ishii,Yukihiko Saeki, MODERN RHEUMATOLOGY, SPRINGER, Vol. 18, No. 3, p. 220-227, 2008/06
  • Osteoclast cell fusion: mechanisms and molecules, Masaru Ishii,Yukihiko Saeki, MODERN RHEUMATOLOGY, SPRINGER, Vol. 18, No. 3, p. 220-227, 2008/06
  • Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging, Ronald N. Germain,Marc Bajenoff,Flora Castellino,Marcello Chieppa,Jackson G. Egen,Alex Y. C. Huang,Masaru Ishii,Lily Y. Koo,Hai Qi, IMMUNOLOGICAL REVIEWS, WILEY, Vol. 221, p. 163-181, 2008/02
  • Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging, Ronald N. Germain,Marc Bajenoff,Flora Castellino,Marcello Chieppa,Jackson G. Egen,Alex Y. C. Huang,Masaru Ishii,Lily Y. Koo,Hai Qi, IMMUNOLOGICAL REVIEWS, WILEY, Vol. 221, p. 163-181, 2008/02
  • Abundant expression of tetraspanin CD9 in activated osteoclasts in ovariectomy-induced osteoporosis and in bone erosions of collagen-induced arthritis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, RHEUMATOLOGY INTERNATIONAL, SPRINGER HEIDELBERG, Vol. 28, No. 3, p. 225-231, 2008/01
  • Abundant expression of tetraspanin CD9 in activated osteoclasts in ovariectomy-induced osteoporosis and in bone erosions of collagen-induced arthritis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, RHEUMATOLOGY INTERNATIONAL, SPRINGER HEIDELBERG, Vol. 28, No. 3, p. 225-231, 2008/01
  • RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway, Kaori Iwai,Masato Koike,Shiro Ohshima,Kunio Miyatake,Yasuo Uchiyama,Yukihiko Saeki,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 22, No. 10, p. 1612-1620, 2007/10
  • Autoantibodies to cyclic citrullinated peptide 2 (CCP2) are superior to other potential diagnostic biomarkers for predicting rheumatoid arthritis in early undifferentiated arthritis, Eriko Kudo-Tanaka,Shiro Ohshima,Masaru Ishii,Toru Mima,Masato Matsushita,Naoto Azuma,Yoshinori Harada,Yoshinori Katada,Hitomi Ikeue,Mitsuko Umeshita-Sasai,Kunio Miyatake,Yukihiko Saeki, CLINICAL RHEUMATOLOGY, SPRINGER, Vol. 26, No. 10, p. 1627-1633, 2007/10
  • RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway, Kaori Iwai,Masato Koike,Shiro Ohshima,Kunio Miyatake,Yasuo Uchiyama,Yukihiko Saeki,Masaru Ishii, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 22, No. 10, p. 1612-1620, 2007/10
  • Autoantibodies to cyclic citrullinated peptide 2 (CCP2) are superior to other potential diagnostic biomarkers for predicting rheumatoid arthritis in early undifferentiated arthritis, Eriko Kudo-Tanaka,Shiro Ohshima,Masaru Ishii,Toru Mima,Masato Matsushita,Naoto Azuma,Yoshinori Harada,Yoshinori Katada,Hitomi Ikeue,Mitsuko Umeshita-Sasai,Kunio Miyatake,Yukihiko Saeki, CLINICAL RHEUMATOLOGY, SPRINGER, Vol. 26, No. 10, p. 1627-1633, 2007/10
  • Visualization and identification of IL-7 producing cells, Scott K. Durum,Soren Warming,Scott M. Lawrence,Masaru Ishii,Mehrnoosh Abshari,Lionel Feigenbaum,A. Valance Washington,Andrew C. Warner,David J. Sims,Wen Qing Li,Julie A. Hixon,Daniel H. D. Gray,Benjamin E. Rich,Matthew Morrow,Miriam R. Anver,James Cherry,Dieter Naf,Lawrence R. Sternberg,Daniel W. MeVicar,Andrew G. Farr,Ronald N. Germain,Keith Rogers,Neal G. Copeland,Renata Mazzucchelli, CYTOKINE, ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, Vol. 39, No. 1, p. 9-10, 2007/07
  • Expression and function of transmembrane-4 superfamily (tetraspanin) proteins in osteoclasts: Reciprocal roles of Tspan-5 and NET-6 during osteoclastogenesis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, Allergology International, Japanese Society of Allergology, Vol. 56, No. 4, p. 457-463, 2007
  • A serological switching from anti-dsDNA to anti-Sm antibodies coincided with severe clinical manifestations of systemic lupus erythematosus (hemophagocytosis, profundus and psychosis), M. Ishii,Y. Muramoto,H. Kosaka,S. Ohshima,T. Mima,Y. Katada,S. Hirohata,Y. Saeki, LUPUS, SAGE PUBLICATIONS LTD, Vol. 16, No. 1, p. 67-69, 2007
  • Expression and function of transmembrane-4 superfamily (tetraspanin) proteins in osteoclasts: Reciprocal roles of Tspan-5 and NET-6 during osteoclastogenesis, Kaori Iwai,Masaru Ishii,Shiro Ohshima,Kunio Miyatake,Yukihiko Saeki, Allergology International, Japanese Society of Allergology, Vol. 56, No. 4, p. 457-463, 2007
  • A serological switching from anti-dsDNA to anti-Sm antibodies coincided with severe clinical manifestations of systemic lupus erythematosus (hemophagocytosis, profundus and psychosis), M. Ishii,Y. Muramoto,H. Kosaka,S. Ohshima,T. Mima,Y. Katada,S. Hirohata,Y. Saeki, LUPUS, SAGE PUBLICATIONS LTD, Vol. 16, No. 1, p. 67-69, 2007
  • Study of zebrafish pigmentation mutant Jaguar (Obelix), Motoko Iwashita,Masakatsu Watanabe,Masaru Ishii,Yoshihisa Kurachi,Norihiro Okada,Shigeru Kondo, ZOOLOGICAL SCIENCE, ZOOLOGICAL SOC JAPAN, Vol. 23, No. 12, p. 1177-1177, 2006/12
  • Pigment pattern in jaguar/obelix zebrafish is caused by a Kir7.1 mutation: Implications for the regulation of melanosome movement, Motoko Iwashita,Masakatsu Watanabe,Masaru Ishii,Tim Chen,Stephen L. Johnson,Yoshihisa Kurachi,Norihiro Okada,Shigeru Kondo, PLOS GENETICS, PUBLIC LIBRARY SCIENCE, Vol. 2, No. 11, p. 1861-1870, 2006/11
  • Pigment pattern in jaguar/obelix zebrafish is caused by a Kir7.1 mutation: Implications for the regulation of melanosome movement, Motoko Iwashita,Masakatsu Watanabe,Masaru Ishii,Tim Chen,Stephen L. Johnson,Yoshihisa Kurachi,Norihiro Okada,Shigeru Kondo, PLOS GENETICS, PUBLIC LIBRARY SCIENCE, Vol. 2, No. 11, p. 1861-1870, 2006/11
  • Muscarinic acetylcholine receptors, Masaru Ishii,Yoshihisa Kurachi, Current Pharmaceutical Design, Vol. 12, No. 28, p. 3573-3581, 2006/10
  • RANKL-induced expression of tetraspanin CD9 is essential for cell fusion during osteoclastogenesis., Kaori Iwai,Masaru Ishii,Shiro Ohshima,Yukihiko Saeki, ARTHRITIS AND RHEUMATISM, WILEY-LISS, Vol. 54, No. 9, p. S531-S531, 2006/09
  • Spot pattern of leopard Danio is caused by mutation in the zebrafish connexin41.8 gene, Masakatsu Watanabe,Motoko Iwashita,Masaru Ishii,Yoshihisa Kurachi,Atsushi Kawakami,Shigeru Kondo,Norihiro Okada, EMBO REPORTS, NATURE PUBLISHING GROUP, Vol. 7, No. 9, p. 893-897, 2006/09
  • Spot pattern of leopard Danio is caused by mutation in the zebrafish connexin41.8 gene, Masakatsu Watanabe,Motoko Iwashita,Masaru Ishii,Yoshihisa Kurachi,Atsushi Kawakami,Shigeru Kondo,Norihiro Okada, EMBO REPORTS, NATURE PUBLISHING GROUP, Vol. 7, No. 9, p. 893-897, 2006/09
  • Minocycline-induced vasculitis fulfilling the criteria of polyarteritis nodosa, Yoshinori Katada,Yoshinori Harada,Naoto Azuma,Kengo Matsumoto,Haruko Terada,Eriko Kudo,Masaru Ishii,Hiroyuki Yamane,Suguru Yamamoto,Shiro Ohshima,Toru Mima,Toshio Tanaka,Yukihiko Saeki, Modern Rheumatology, Vol. 16, No. 4, p. 256-259, 2006/08
  • Minocycline-induced vasculitis fulfilling the criteria of polyarteritis nodosa, Yoshinori Katada,Yoshinori Harada,Naoto Azuma,Kengo Matsumoto,Haruko Terada,Eriko Kudo,Masaru Ishii,Hiroyuki Yamane,Suguru Yamamoto,Shiro Ohshima,Toru Mima,Toshio Tanaka,Yukihiko Saeki, Modern Rheumatology, Vol. 16, No. 4, p. 256-259, 2006/08
  • RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis, M Ishii,K Iwai,M Koike,S Ohshima,E Kudo-Tanaka,T Ishii,T Mima,Y Katada,K Miyatake,Y Uchiyama,Y Saeki, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 21, No. 6, p. 965-976, 2006/06
  • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis, N Takegahara,H Takamatsu,T Toyofuku,T Tsujimura,T Okuno,K Yukawa,M Mizui,M Yamamoto,DVR Prasad,K Suzuki,M Ishii,K Terai,M Moriya,Y Nakatsuji,S Sakoda,S Sato,S Akira,K Takeda,M Inui,T Takai,M Ikawa,M Okabe,A Kumanogoh,H Kikutani, NATURE CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 8, No. 6, p. 615-622, 2006/06
  • RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis, M Ishii,K Iwai,M Koike,S Ohshima,E Kudo-Tanaka,T Ishii,T Mima,Y Katada,K Miyatake,Y Uchiyama,Y Saeki, JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, Vol. 21, No. 6, p. 965-976, 2006/06
  • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis, N Takegahara,H Takamatsu,T Toyofuku,T Tsujimura,T Okuno,K Yukawa,M Mizui,M Yamamoto,DVR Prasad,K Suzuki,M Ishii,K Terai,M Moriya,Y Nakatsuji,S Sakoda,S Sato,S Akira,K Takeda,M Inui,T Takai,M Ikawa,M Okabe,A Kumanogoh,H Kikutani, NATURE CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 8, No. 6, p. 615-622, 2006/06
  • RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis, Masaru Ishii,Yukihiko Saeki, JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 176, p. S193-S193, 2006/04
  • Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins, RA Roof,YF Jin,DL Roman,RK Sunahara,M Ishii,HI Mosberg,RR Neubig, CHEMICAL BIOLOGY & DRUG DESIGN, BLACKWELL PUBLISHING, Vol. 67, No. 4, p. 266-274, 2006/04
  • Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins, RA Roof,YF Jin,DL Roman,RK Sunahara,M Ishii,HI Mosberg,RR Neubig, CHEMICAL BIOLOGY & DRUG DESIGN, BLACKWELL PUBLISHING, Vol. 67, No. 4, p. 266-274, 2006/04
  • Muscarinic acetylcholine receptors., Ishii M,Kurachi Y, Current Pharmaceutical Design, Vol. 12, p. 3573-3581, 2006
  • Carvedilol blocks cardiac K-ATP and K-G but not I-K1 channels by acting at the bundle-crossing regions, J Kikuta,M Ishii,K Kishimoto,Y Kurachi, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 529, No. 1-3, p. 47-54, 2006/01
  • Carvedilol blocks cardiac K-ATP and K-G but not I-K1 channels by acting at the bundle-crossing regions, J Kikuta,M Ishii,K Kishimoto,Y Kurachi, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 529, No. 1-3, p. 47-54, 2006/01
  • In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: Possible involvement of lipid raft, M Ishii,M Ikushima,Y Kurachi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 338, No. 2, p. 839-846, 2005/12
  • In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: Possible involvement of lipid raft, M Ishii,M Ikushima,Y Kurachi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 338, No. 2, p. 839-846, 2005/12
  • Investigation of the block and facilitation effects by nifekalant in a HERG channel, Y Hosaka,M Yamada,M Ishii,H Hibino,Y Kurachi, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 19, No. 5, p. A1159-A1160, 2005/03
  • Phosphatidylinositol 3,4,5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action, M Ishii,S Fujita,M Yamada,Y Hosaka,Y Kurachi, BIOCHEMICAL JOURNAL, PORTLAND PRESS, Vol. 385, No. 1, p. 65-73, 2005/01
  • Chronic active EBV infection and Hypersensitivity to Mosquito Bites: Pathophysiology and Pharmacology., Ishii M,Ohshima S,Saeki Y, Current Rheumatology Reviews, Vol. 1, p. 65-70, 2005
  • Phosphatidylinositol 3,4,5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action, M Ishii,S Fujita,M Yamada,Y Hosaka,Y Kurachi, BIOCHEMICAL JOURNAL, PORTLAND PRESS, Vol. 385, No. 1, p. 65-73, 2005/01
  • Chronic active EBV infection and Hypersensitivity to Mosquito Bites: Pathophysiology and Pharmacology., Ishii M,Ohshima S,Saeki Y, Current Rheumatology Reviews, Vol. 1, p. 65-70, 2005
  • Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: Implication for dimerization of nucleotide-binding domains to induce channel opening, M Yamada,M Ishii,H Hibino,Y Kurachi, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 66, No. 4, p. 807-816, 2004/10
  • Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K+ channels: Implication for dimerization of nucleotide-binding domains to induce channel opening, M Yamada,M Ishii,H Hibino,Y Kurachi, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 66, No. 4, p. 807-816, 2004/10
  • Assays of RGS protein modulation by phosphatidylinositides and calmodulin, Masaru Ishii,Yoshihisa Kurachi, Methods in Enzymology, Vol. 389, p. 105-118, 2004
  • Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential, H Hibino,K Higashi-Shingai,A Fujita,K Iwai,M Ishii,Y Kurachi, EUROPEAN JOURNAL OF NEUROSCIENCE, WILEY-BLACKWELL, Vol. 19, No. 1, p. 76-84, 2004/01
  • Cell signal control of the G protein-gated potassium channel and its subcellular localization., Kurachi Y,Ishii M, The Journal of Physiology, Vol. 554, No. 2, p. 285-294, 2004
  • Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential, H Hibino,K Higashi-Shingai,A Fujita,K Iwai,M Ishii,Y Kurachi, EUROPEAN JOURNAL OF NEUROSCIENCE, WILEY-BLACKWELL, Vol. 19, No. 1, p. 76-84, 2004/01
  • Assay of RGS protein modulation by phosphatidylinositides and calmodulin., Ishii M,Kurachi Y, Methods in Enzymology, Vol. 389, p. 105-118, 2004
  • Physiological actions of regulators of G-protein signaling (RGS) proteins, M Ishii,Y Kurachi, LIFE SCIENCES, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 74, No. 2-3, p. 163-171, 2003/12
  • Physiological actions of regulators of G-protein signaling (RGS) proteins, M Ishii,Y Kurachi, LIFE SCIENCES, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 74, No. 2-3, p. 163-171, 2003/12
  • Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina, M Ishii,A Fujita,K Iwai,S Kusaka,K Higashi,A Inanobe,H Hibino,Y Kurachi, AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 285, No. 2, p. C260-C267, 2003/08
  • Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K+ channels in retina, M Ishii,A Fujita,K Iwai,S Kusaka,K Higashi,A Inanobe,H Hibino,Y Kurachi, AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 285, No. 2, p. C260-C267, 2003/08
  • Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders, M Ishii,N Yamaguchi,S Ohshima,T Ishii,KL Mori,H Kimura,T Morishima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 42, No. 3, p. 250-254, 2003/03
  • Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders, M Ishii,N Yamaguchi,S Ohshima,T Ishii,KL Mori,H Kimura,T Morishima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 42, No. 3, p. 250-254, 2003/03
  • Ca2+-elevation evoked by depolarization and formation of Ca2+/calmodulin regulates G-protein-cycle by removing PIP3-mediated inhibition of RGS protein, M Ishii,A Inanobe,Y Kurachi, BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, Vol. 84, No. 2, p. 38A-38A, 2003/02
  • A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5, T Ishii,T Tatekawa,M Koseto,M Ishii,H Kobayashi,M Koike,T Fujii,Y Saeki, EUROPEAN JOURNAL OF HAEMATOLOGY, BLACKWELL MUNKSGAARD, Vol. 70, No. 2, p. 115-118, 2003/02
  • A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5, T Ishii,T Tatekawa,M Koseto,M Ishii,H Kobayashi,M Koike,T Fujii,Y Saeki, EUROPEAN JOURNAL OF HAEMATOLOGY, BLACKWELL MUNKSGAARD, Vol. 70, No. 2, p. 115-118, 2003/02
  • Idiopathic portal hypertension in a systemic sclerosis patient heterozygous for factor V Leiden mutation, M Ishii,Y Katada, RHEUMATOLOGY INTERNATIONAL, SPRINGER-VERLAG, Vol. 23, No. 1, p. 44-46, 2003/01
  • Cardiac conduction and arrhythmia: Insights from Nkx2.5 mutations in mouse and humans, Patrick Y. Jay,Charles I. Berul,Makoto Tanaka,Masao Ishii,Yoshihisa Kurachi,Seigo Izumo,Gourdie,Markwald,Thompson,Burch, Novartis Foundation Symposium, Vol. 250, p. 227-241, 2003
  • Idiopathic portal hypertension in a systemic sclerosis patient heterozygous for factor V Leiden mutation, M Ishii,Y Katada, RHEUMATOLOGY INTERNATIONAL, SPRINGER-VERLAG, Vol. 23, No. 1, p. 44-46, 2003/01
  • Cell signal control of the G protein-gated potassium channel and its subcellular localization., Kurachi Y,Ishii M, The Journal of Physiology, Vol. 554, No. 2, p. 285-294, 2003
  • Cardiac conduction and arrhythmia: Insights from Nkx2.5 mutations in mouse and humans, Patrick Y. Jay,Charles I. Berul,Makoto Tanaka,Masao Ishii,Yoshihisa Kurachi,Seigo Izumo,Gourdie,Markwald,Thompson,Burch, Novartis Foundation Symposium, Vol. 250, p. 227-241, 2003
  • Depolarization-dependent control of G-protein-cycle by RGS proteins forms a characteristic gating property of muscarinic G-protein-gated potassium channels in the heart: Implication for cholinergic regulation of heart beats, M Ishii,A Inanobe,Y Kurachi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 19, p. 89-89, 2002/11
  • The 14-3-3 protein as a novel regulator of ion channel localisation, M Ishii,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 545, No. 1, p. 2-2, 2002/11
  • A possible mechanism of NK cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) in a patient with chronic active Epstein-Barr virus infection (CAEBV) and severe hypersensitivity to mosquito bites (SHMB), S Ohshima,M Ishii,H Asada,T Tatekawa,N Yamaguchi,H Kobayashi,T Ishii,T Mima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 41, No. 8, p. 651-656, 2002/08
  • A possible mechanism of NK cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) in a patient with chronic active Epstein-Barr virus infection (CAEBV) and severe hypersensitivity to mosquito bites (SHMB), S Ohshima,M Ishii,H Asada,T Tatekawa,N Yamaguchi,H Kobayashi,T Ishii,T Mima,Kawase, I,Y Saeki, INTERNAL MEDICINE, JAPAN SOC INTERNAL MEDICINE, Vol. 41, No. 8, p. 651-656, 2002/08
  • PIP3 inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel, Masaru Ishii,Atsushi Inanobe,Yoshihisa Kurachi, Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 7, p. 4325-4330, 2002/04/02
  • PIPS inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel, M Ishii,A Inanobe,Y Kurachi, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 99, No. 7, p. 4325-4330, 2002/04
  • The 14-3-3 protein as a novel regulator of ion channel localisation., Ishii M,Kurachi Y, The Journal of Physiology, Vol. 545, No. 1, 2002
  • A mouse model of congenital heart disease: Cardiac arrhythmias and atrial septal defect caused by haploin sufficiency of the cardiac transcription factor Csx/Nkx2.5, M Tanaka,CI Berul,M Ishii,PY Jay,H Wakimoto,P Douglas,N Yamasaki,T Kawamoto,J Gehrmann,CT Maguire,M Schinke,CE Seidman,JG Seidman,Y Kurachi,S Izumo, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, Vol. 67, p. 317-325, 2002
  • A mouse model of congenital heart disease: Cardiac arrhythmias and atrial septal defect caused by haploin sufficiency of the cardiac transcription factor Csx/Nkx2.5, M Tanaka,CI Berul,M Ishii,PY Jay,H Wakimoto,P Douglas,N Yamasaki,T Kawamoto,J Gehrmann,CT Maguire,M Schinke,CE Seidman,JG Seidman,Y Kurachi,S Izumo, COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, Vol. 67, p. 317-325, 2002
  • Ca2+ elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart, M Ishii,A Inanobe,S Fujita,YA Makino,Y Hosoya,Y Kurachi, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 89, No. 11, p. 1045-1050, 2001/11
  • Ca2+ elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart, M Ishii,A Inanobe,S Fujita,YA Makino,Y Hosoya,Y Kurachi, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 89, No. 11, p. 1045-1050, 2001/11
  • RGS modulates the membrane potential-dependent gating property of muscarinic G protein-gated potassium channels: Possible role for cholinergic regulation of the heart, M Ishii,A Inanobe,S Fujita,Y Makino,Y Hosoya,Y Kurachi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 17, p. 277-277, 2001/10
  • Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel, A Inanobe,S Fujita,Y Makino,K Matsushita,M Ishii,M Chachin,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 535, No. 1, p. 133-143, 2001/08
  • Interaction between the RGS domain of RGS4 with G protein alpha subunits mediates the voltage-dependent relaxation of the G protein-gated potassium channel, A Inanobe,S Fujita,Y Makino,K Matsushita,M Ishii,M Chachin,Y Kurachi, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 535, No. 1, p. 133-143, 2001/08
  • A RGS protein confers agonist-dependent relaxation gating to a G protein-gated K+ channel., S Fujita,A Inanobe,M Chachin,Y Makino,M Ishii,K Matsushita,Y Kurachi, BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, Vol. 80, No. 1, p. 631A-631A, 2001/01
  • Possible association of "shrinking lung" and anti-Ro/SSA antibody, M Ishii,H Uda,T Yamagami,Y Katada, ARTHRITIS AND RHEUMATISM, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 11, p. 2612-2613, 2000/11
  • Possible association of "shrinking lung" and anti-Ro/SSA antibody, M Ishii,H Uda,T Yamagami,Y Katada, ARTHRITIS AND RHEUMATISM, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 11, p. 2612-2613, 2000/11
  • Expression and clustered distribution of an inwardly rectifying potassium channel, K-AB-2/Kir4.1, on mammalian retinal Muller cell membrane: Their regulation by insulin and laminin signals, M Ishii,Y Horio,Y Tada,H Hibino,A Inanobe,M Ito,M Yamada,T Gotow,Y Uchiyama,Y Kurachi, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 17, No. 20, p. 7725-7735, 1997/10
  • Expression and clustered distribution of an inwardly rectifying potassium channel, K-AB-2/Kir4.1, on mammalian retinal Muller cell membrane: Their regulation by insulin and laminin signals, M Ishii,Y Horio,Y Tada,H Hibino,A Inanobe,M Ito,M Yamada,T Gotow,Y Uchiyama,Y Kurachi, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 17, No. 20, p. 7725-7735, 1997/10
  • Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90, Y Horio,H Hibino,A Inanobe,M Yamada,M Ishii,Y Tada,E Satoh,Y Hata,Y Takai,Y Kurachi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 20, p. 12885-12888, 1997/05
  • Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90, Y Horio,H Hibino,A Inanobe,M Yamada,M Ishii,Y Tada,E Satoh,Y Hata,Y Takai,Y Kurachi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 20, p. 12885-12888, 1997/05

Publications

  • G protein and effectors., Encyclopedia of Endocrine Diseases. Academic Press, 2004

Works

  • G蛋白質制御蛋白質（RGS蛋白質）の阻害剤の開発と活性測定（米国ミシガン大学との国際共同研究）, 2005 -

Awards

  • 日本免疫学会賞, 特定非営利活動法人 日本免疫学会, 2022/12
  • 大阪科学賞, 大阪府・大阪市・一般財団法人大阪科学技術センター, 2020/11
  • 日本リウマチ学会・学会賞, 一般社団法人 日本リウマチ学会, 2020/07
  • 日本薬理学会・江橋節郎賞, 公益社団法人 日本薬理学会, 2018/12
  • 尾形学術振興賞, 一般社団法人 日本骨代謝学会, 2018/07
  • 第11回・日本学術振興会賞, 石井 優, 日本学術振興会, 2014/12
  • 平成25年度日本医師会・医学研究奨励賞, 石井 優, 日本医師会, 2013/11
  • 学術賞, 石井 優, 日本骨代謝学会, 2013/05
  • 若手研究者表彰事業・会長賞, 石井 優, 長寿科学振興財団, 2011/12
  • 第41回・最優秀理事長賞, 石井 優, 病態代謝研究会, 2010/11
  • 科学技術分野の文部科学大臣表彰・若手科学者賞, 石井 優, 文部科学省, 2010/04
  • Young Investigator’s Award, The Japanese College of Rheumatology, 2007
  • 日本リウマチ学会・学会奨励賞, 2007
  • Young Investigator's Award, The Japanse Society of Allergology, 2006
  • 第２回・日本アレルギー学会学術大会賞, 2006
  • 31st International Congress of Electrocardiology, Young Investigator’s Award, 1st Prize, 2005
  • Young Investigator’s Award, 1st Prize, 31st International Congress of Electrocardiology, 2004
  • Best Presentation Award, The Japanese Pharmacological Society, 2004
  • 第77回日本薬理学会年会・優秀発表賞, 2004
  • Best Presentation Award, The Japanese Pharmacological Society, 2003
  • 第76回日本薬理学会年会・優秀発表賞, 2003
  • Young Investigator Award, The Japanese Society of Electrocardiology, 2002
  • Young Investigator Award, The 2nd Annual ASPET G protein-coupled receptor symposium., 2002
  • The 2nd Annual ASPET G protein-coupled receptor symposium Young Investigator Award, 2002
  • 日本心電学会学術奨励賞最優秀賞, 2002
  • 第10回日本心臓財団・入澤宏記念研究奨励賞, 2001

Committee Memberships

  • 日本リウマチ学会 理事, 2023/04 - Present
  • 日本臨床免疫学会 評議員, 2016 - Present
  • 日本炎症・再生医学会 理事, 2016 - Present
  • 日本骨免疫学会 理事, 2015 - Present
  • 日本免疫学会 評議員, 2015 - Present
  • 日本骨代謝学会, 評議員, 2013 - Present
  • 日本リウマチ学会, 評議員, 2012 - Present
  • 日本薬理学会, 学術評議員, 2006 - Present
  • 日本骨代謝学会, 理事, 2017/07 - 2023/06
  • 日本アレルギー学会, 専門医, 2006 - 2011