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Hayashi Takashi

林 高史

Graduate School of Engineering Division of Applied Chemistry, Professor

Education

  • 1985/04 - 1990/03, Kyoto University, Graduate School of Engineering
  • 1981/04 - 1985/03, Kyoto University, Faculty of Engineering

Research History

  • 2005/04 - Present, Faculty of Engineering, Osaka University, Department of Applied Chemistry, professor
  • 2005/04 - 2007/03, Institute for Molecular Science, Visiting Professor
  • 1997 - 2005, Kyushu University
  • 2000 - 2003, 科学技術振興事業団 さきがけ21「変換と制御」研究員
  • 1990 - 1997, 京都大学 助手
  • 1995 - 1996, スクリプス研究所(アメリカ、カリフォルニア州) 客員研究員

Research Areas

  • Nanotechnology/Materials, Structural/physical organic chemistry, Supramolecular Chemistry
  • Life sciences, Bioorganic chemistry, Protein Engineering
  • Nanotechnology/Materials, Biochemistry
  • Nanotechnology/Materials, Synthetic organic chemistry
  • Nanotechnology/Materials, Inorganic and coordination chemistry, Bioinorganic Chemistry
  • Nanotechnology/Materials, Molecular biochemistry

Professional Memberships

  • 錯体化学会
  • 高分子学会
  • 近畿化学協会
  • 有機合成化学協会
  • アメリカ化学会 (American Chemical Society)
  • 日本化学会
  • Society of Porphyrins and Phthalocyanines (SPP)
  • Society of Biological Inorganic Chemistry (SBIC)
  • American Chemical Society (Inorg. Div. and Organic Div.)

Papers

  • Chitin‐ and Streptavidin‐Mediated Affinity Purification Systems: A Screening Platform for Enzyme Discovery, Shunsuke Kato,Koki Takeuchi,Motonao Iwaki,Kentaro Miyazaki,Kohsuke Honda,Takashi Hayashi, Angewandte Chemie International Edition, Wiley, 2023/06/06
  • Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold, Shunsuke Kato,Akira Onoda,Ulrich Schwaneberg,Takashi Hayashi, Journal of the American Chemical Society, American Chemical Society (ACS), 2023/03/09
  • Disulfide Bond-mediated Oligomerization of a Green Fluorescent Protein in Solution, Julian Wong Soon,Koji Oohora,Takayuki Uchihashi,Takashi Hayashi, Chemistry Letters, Vol. 52, No. 2, p. 105-109, 2023/02
  • Ethylbenzene oxidation by a hybrid catalysis system of reconstituted myoglobin and silica-protected PdAu nanoparticles under a hydrogen-oxygen mixed atmosphere, Koji Oohora,Yoshiyuki Kagawa,Yasutaka Kuwahara,Hiromi Yamashita,Takashi Hayashi, Journal of Porphyrins and Phthalocyanines, 2023
  • A disulphide bond-mediated hetero-dimer of a hemoprotein and a fluorescent protein exhibiting efficient energy transfer, Julian Wong Soon,Koji Oohora,Takashi Hayashi, RSC Advances, Vol. 12, No. 44, p. 28519-28524, 2022/10/06
  • Reactivity of Myoglobin Reconstituted with Cobalt Corrole toward Hydrogen Peroxide, Koji Oohora,Hirotaka Tomoda,Takashi Hayashi, International Journal of Molecular Sciences, Vol. 23, No. 9, 2022/05/01
  • DNA-Mediated Protein Shuttling between Coacervate-Based Artificial Cells, Tsuyoshi Mashima,Marleen H.M.E. van Stevendaal,Femke R.A. Cornelissens,Alexander F. Mason,Bas J.H.M. Rosier,Wiggert J. Altenburg,Koji Oohora,Shota Hirayama,Takashi Hayashi,Jan C.M. van Hest,Luc Brunsveld, Angewandte Chemie - International Edition, Vol. 61, No. 17, 2022/04
  • Dynamic Protease Activation on a Multimeric Synthetic Protein Scaffold via Adaptable DNA‐Based Recruitment Domains, Tsuyoshi Mashima,Bas J. H. M. Rosier,Koji Oohora,Tom F. A. Greef,Takashi Hayashi,Luc Brunsveld, Angewandte Chemie International Edition, Wiley, Vol. 60, No. 20, p. 11262-11266, 2021/05/10
  • Thermally Controlled Construction of Fe-N <inf>x</inf>Active Sites on the Edge of a Graphene Nanoribbon for an Electrocatalytic Oxygen Reduction Reaction, Koki Matsumoto,Akira Onoda,Tomoyuki Kitano,Takao Sakata,Hidehiro Yasuda,Stéphane Campidelli,Takashi Hayashi, ACS Applied Materials and Interfaces, Vol. 13, No. 13, p. 15101-15112, 2021/04
  • Construction of a whole-cell biohybrid catalyst using a Cp*Rh(III)-dithiophosphate complex as a precursor of a metal cofactor, Shunsuke Kato,Akira Onoda,Alexander R. Grimm,Ulrich Schwaneberg,Takashi Hayashi, Journal of Inorganic Biochemistry, Vol. 216, 2021/03
  • Directed Evolution of a Cp*Rh<sup>III</sup>-Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification, Shunsuke Kato,Akira Onoda,Naomasa Taniguchi,Ulrich Schwaneberg,Takashi Hayashi, ChemBioChem, Vol. 22, No. 4, p. 679-685, 2021/02/15
  • Myoglobins engineered with artificial cofactors serve as artificial metalloenzymes and models of natural enzymes, Koji Oohora,Takashi Hayashi, Dalton Transactions, Vol. 50, No. 6, p. 1940-1949, 2021/02/14
  • A supramolecular assembly of hemoproteins formed in a star-shaped structure via heme–heme pocket interactions, Julian Wong Soon,Koji Oohora,Shota Hirayama,Takashi Hayashi, International Journal of Molecular Sciences, Vol. 22, No. 3, p. 1-13, 2021/02/01
  • Functional Myoglobin Model Composed of a Strapped Porphyrin/Cyclodextrin Supramolecular Complex with an Overhanging COOH That Increases O<inf>2</inf>/CO Binding Selectivity in Aqueous Solution, Qiyue Mao,Pradip K. Das,Stéphane Le Gac,Bernard Boitrel,Vincent Dorcet,Koji Oohora,Takashi Hayashi,Hiroaki Kitagishi, Inorganic Chemistry, Vol. 60, No. 16, p. 12392-12404, 2021
  • Effect of Molecule-Substrate Interactions on the Adsorption of meso-Dibenzoporphycene Tautomers Studied by Scanning Probe Microscopy and First-Principles Calculations, Tomoko K. Shimizu,Carlos Romero-Muñiz,Oleksandr Stetsovych,Jaime Carracedo-Cosme,Michael Ellner,Pablo Pou,Koji Oohora,Takashi Hayashi,Ruben Perez,Oscar Custance, Journal of Physical Chemistry C, Vol. 124, No. 49, p. 26759-26768, 2020/12/10
  • Incorporation of a Cp*Rh(III)-dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp<sup>2</sup>)-H Bond Functionalization, Shunsuke Kato,Akira Onoda,Alexander R. Grimm,Kengo Tachikawa,Ulrich Schwaneberg,Takashi Hayashi, Inorganic Chemistry, Vol. 59, No. 19, p. 14457-14463, 2020/10/05
  • Chiral paddle-wheel diruthenium complexes for asymmetric catalysis, Taku Miyazawa,Takuro Suzuki,Yuhei Kumagai,Koji Takizawa,Takashi Kikuchi,Shunsuke Kato,Akira Onoda,Takashi Hayashi,Yuji Kamei,Futa Kamiyama,Masahiro Anada,Masahiro Kojima,Tatsuhiko Yoshino,Shigeki Matsunaga, Nature Catalysis, Vol. 3, No. 10, p. 851-858, 2020/10/01
  • Methane generation and reductive debromination of benzylic position by reconstituted myoglobin containing nickel tetradehydrocorrin as a model of methyl-coenzyme M reductase, Yuta Miyazaki,Koji Oohora,Takashi Hayashi, Inorganic Chemistry, Vol. 59, No. 17, p. 11995-12004, 2020/09/08
  • Triazolecarbaldehyde Reagents for One-Step N-Terminal Protein Modification, Akira Onoda,Nozomu Inoue,Eigo Sumiyoshi,Takashi Hayashi, ChemBioChem, Vol. 21, No. 9, p. 1274-1278, 2020/05/04
  • Construction of a hexameric hemoprotein sheet and direct observation of dynamic processes of its formation, Oohora, K.,Hirayama, S.,Uchihashi, T.,Hayashi, T., Chemistry Letters, Vol. 49, No. 2, 2020
  • Thermoresponsive Micellar Assembly Constructed from a Hexameric Hemoprotein Modified with Poly(N-isopropylacrylamide) toward an Artificial Light-Harvesting System, Hirayama, S.,Oohora, K.,Uchihashi, T.,Hayashi, T., Journal of the American Chemical Society, Vol. 142, No. 4, p. 1822-1831, 2020
  • Supramolecular dimerization of a hexameric hemoprotein via multiple pyrene-pyrene interactions, Oohora, K.,Hirayama, S.,Mashima, T.,Hayashi, T., Journal of Porphyrins and Phthalocyanines, World Scientific Pub Co Pte Lt, Vol. 24, No. 1-3, p. 259-267, 2020
  • A ring-shaped hemoprotein trimer thermodynamically controlled by the supramolecular heme-heme pocket interaction, Oohora, K.,Kajihara, R.,Fujimaki, N.,Uchihashi, T.,Hayashi, T., Chemical Communications, Vol. 55, No. 11, p. 1544-1547, 2019
  • Electrochemical CO<inf>2</inf> reduction by a cobalt bipyricorrole complex: Decrease of an overpotential value derived from monoanionic ligand character of the porphyrinoid species, Ogawa, A.,Oohora, K.,Gu, W.,Hayashi, T., Chemical Communications, Vol. 55, No. 4, p. 493-496, 2019
  • Photoinduced electron transfer within supramolecular hemoprotein co-assemblies and heterodimers containing Fe and Zn porphyrins, Kajihara, R.,Oohora, K.,Hayashi, T., Journal of Inorganic Biochemistry, Vol. 193, p. 42-51, 2019
  • Arginine residues provide a multivalent effect for cellular uptake of a hemoprotein assembly, Oohora, K.,Kajihara, R.,Jiromaru, M.,Kitagishi, H.,Hayashi, T., Chemistry Letters, Vol. 48, No. 3, p. 295-298, 2019
  • Hemoproteins Reconstituted with Artificial Metal Complexes as Biohybrid Catalysts, Oohora, K.,Onoda, A.,Hayashi, T., Accounts of Chemical Research, Vol. 52, No. 4, p. 945-954, 2019
  • Light triggers molecular shuttling in rotaxanes: Control over proximity and charge recombination, Wolf, M.,Ogawa, A.,Bechtold, M.,Vonesch, M.,Wytko, J.A.,Oohora, K.,Campidelli, S.,Hayashi, T.,Guldi, D.M.,Weiss, J., Chemical Science, Vol. 10, No. 13, p. 3846-3853, 2019
  • Myoglobin Reconstituted with Ni Tetradehydrocorrin as a Methane-Generating Model of Methyl-coenzyme M Reductase, Oohora, K.,Miyazaki, Y.,Hayashi, T., Angewandte Chemie - International Edition, Vol. 58, No. 39, p. 13813-13817, 2019
  • Site-Specific Modification of Proteins through N-Terminal Azide Labeling and a Chelation-Assisted CuAAC Reaction, Inoue, N.,Onoda, A.,Hayashi, T., Bioconjugate Chemistry, Vol. 30, No. 9, p. 2427-2434, 2019
  • Methane generation via intraprotein C–S bond cleavage in cytochrome b<inf>562</inf> reconstituted with nickel didehydrocorrin, Miyazaki, Y.,Oohora, K.,Hayashi, T., Journal of Organometallic Chemistry, Vol. 901, 2019
  • Photochemical dyads and triads built on rotaxane architectures, Ogawa Ayumu,Bechtold Mareike,Wolf Maximilian,Wytko Jennifer,Oohora Koji,Hayashi Takashi,Guldi Dirk,Campidelli Stephane,Weiss Jean, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 255, 2018/03/18
  • Artificially Created Metalloenzyme Consisting of an Organometallic Complex Immobilized to a Protein Matrix, Sauer, D.F.,Matsuo, T.,Onoda, A.,Okuda, J.,Hayashi, T., Advances in Bioorganometallic Chemistry, p. 307-328, 2018
  • Nonprecious-metal Fe/N/C Catalysts Prepared from π-Expanded Fe Salen Precursors toward an Efficient Oxygen Reduction Reaction, Tanaka, Y.,Onoda, A.,Okuoka, S.-I.,Kitano, T.,Matsumoto, K.,Sakata, T.,Yasuda, H.,Hayashi, T., ChemCatChem, Wiley, Vol. 10, No. 4, p. 653-653, 2018
  • Roles of N- and C-terminal domains in the ligand-binding properties of cytoglobin, Hanai, S.,Tsujino, H.,Yamashita, T.,Torii, R.,Sawai, H.,Shiro, Y.,Oohora, K.,Hayashi, T.,Uno, T., Journal of Inorganic Biochemistry, Elsevier Inc., Vol. 179, p. 1-9, 2018
  • Mitochondria-Targeting Polyamine–Protoporphyrin Conjugates for Photodynamic Therapy, Taba, F.,Onoda, A.,Hasegawa, U.,Enoki, T.,Ooyama, Y.,Ohshita, J.,Hayashi, T., ChemMedChem, John Wiley and Sons Ltd, Vol. 13, No. 1, p. 15-19, 2018
  • Bimetallic M/N/C catalysts prepared from π-expanded metal salen precursors toward an efficient oxygen reduction reaction, Onoda, A.,Tanaka, Y.,Matsumoto, K.,Ito, M.,Sakata, T.,Yasuda, H.,Hayashi, T., RSC Advances, Royal Society of Chemistry, Vol. 8, No. 6, p. 2892-2899, 2018
  • Successive energy transfer within multiple photosensitizers assembled in a hexameric hemoprotein scaffold, Mashima, T.,Oohora, K.,Hayashi, T., Physical Chemistry Chemical Physics, Royal Society of Chemistry, Vol. 20, No. 5, p. 3200-3209, 2018
  • Preparation and characterization of myoglobin reconstituted with Fe(II) oxaporphyrin: The monoanionic macrocycle provides unique cyanide binding behavior for the ferrous species, Meichin, H.,Oohora, K.,Hayashi, T., Inorganica Chimica Acta, Elsevier S.A., Vol. 472, p. 184-191, 2018
  • A water-soluble supramolecular complex that mimics the heme/copper hetero-binuclear site of cytochrome: C oxidase, Kitagishi, H.,Shimoji, D.,Ohta, T.,Kamiya, R.,Kudo, Y.,Onoda, A.,Hayashi, T.,Weiss, J.,Wytko, J.A.,Kano, K., Chemical Science, Royal Society of Chemistry, Vol. 9, No. 7, p. 1989-1995, 2018
  • A Whole Cell E. coli Display Platform for Artificial Metalloenzymes: Poly(phenylacetylene) Production with a Rhodium-Nitrobindin Metalloprotein, Grimm, A.R.,Sauer, D.F.,Polen, T.,Zhu, L.,Hayashi, T.,Okuda, J.,Schwaneberg, U., ACS Catalysis, American Chemical Society, Vol. 8, No. 3, p. 2611-2614, 2018
  • Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis, Grimm, A.R.,Sauer, D.F.,Davari, M.D.,Zhu, L.,Bocola, M.,Kato, S.,Onoda, A.,Hayashi, T.,Okuda, J.,Schwaneberg, U., ACS Catalysis, American Chemical Society, Vol. 8, No. 4, p. 3358-3364, 2018
  • Supramolecular Hemoprotein Assembly with a Periodic Structure Showing Heme-Heme Exciton Coupling, Oohora, K.,Fujimaki, N.,Kajihara, R.,Watanabe, H.,Uchihashi, T.,Hayashi, T., Journal of the American Chemical Society, Vol. 140, No. 32, p. 10145-10148, 2018
  • Synthesis and Characterization of meso-Substituted Cobalt Tetradehydrocorrin and Evaluation of Its Electrocatalytic Behavior Toward CO <inf>2</inf> Reduction and H <inf>2</inf> Evolution, Ogawa, A.,Oohora, K.,Hayashi, T., Inorganic Chemistry, Vol. 57, No. 23, p. 14644-14652, 2018
  • A Heterogeneous Hydrogen-Evolution Catalyst Based on a Mesoporous Organosilica with a Diiron Catalytic Center Modelling [FeFe]-Hydrogenase, Himiyama, T.,Waki, M.,Esquivel, D.,Onoda, A.,Hayashi, T.,Van Der Voort, P.,Inagaki, S., ChemCatChem, Vol. 10, No. 21, p. 4908-4913, 2018
  • Olefin metathesis catalysts embedded in β-barrel proteins: Creating artificial metalloproteins for olefin metathesis, Sauer, D.F.,Schiffels, J.,Hayashi, T.,Schwaneberg, U.,Okuda, J., Beilstein Journal of Organic Chemistry, Vol. 14, p. 2861-2871, 2018
  • Titelbild: A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction (Angew. Chem. 44/2017), Tomoki Himiyama,Naomasa Taniguchi,Shunsuke Kato,Akira Onoda,Takashi Hayashi, Angewandte Chemie, Wiley-Blackwell, Vol. 129, No. 44, 2017/10
  • Cover Picture: A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction (Angew. Chem. Int. Ed. 44/2017), Tomoki Himiyama,Naomasa Taniguchi,Shunsuke Kato,Akira Onoda,Takashi Hayashi, Angewandte Chemie International Edition, Wiley-Blackwell, Vol. 56, No. 44, 2017/10
  • A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction, Tomoki Himiyama,Naomasa Taniguchi,Shunsuke Kato,Akira Onoda,Takashi Hayashi, Angewandte Chemie, Wiley-Blackwell, Vol. 129, No. 44, 2017/10
  • Double active template strategy for functional rotaxane synthesis, Weiss Jean,Wytko Jennifer,Hayashi Takashi,Miyazaki Yuta, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 253, 2017/04/02
  • A supramolecular assembly based on an engineered hemoprotein exhibiting a thermal stimulus-driven conversion to a new distinct supramolecular structure, Oohora, K.,Onuma, Y.,Tanaka, Y.,Onoda, A.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 53, No. 51, p. 6879-6882, 2017
  • Enhanced visible light response of a WO<inf>3</inf> photoelectrode with an immobilized fibrous gold nanoparticle assembly using an amyloid-β peptide, Onoda, A.,Harada, H.,Uematsu, T.,Kuwabata, S.,Yamanaka, R.,Sakurai, S.,Hayashi, T., RSC Advances, ROYAL SOC CHEMISTRY, Vol. 7, No. 2, p. 1089-1092, 2017
  • Redox Potentials of Cobalt Corrinoids with Axial Ligands Correlate with Heterolytic Co-C Bond Dissociation Energies, Morita, Y.,Oohora, K.,Sawada, A.,Kamachi, T.,Yoshizawa, K.,Hayashi, T., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 56, No. 4, p. 1950-1955, 2017
  • Cobalt tetradehydrocorrins coordinated by imidazolate-like histidine in the heme pocket of horseradish peroxidase, Oohora, K.,Tang, N.,Morita, Y.,Hayashi, T., Journal of Biological Inorganic Chemistry, SPRINGER, Vol. 22, No. 5, p. 695-703, 2017
  • A supramolecular assembly based on an engineered hemoprotein exhibiting a thermal stimulus-driven conversion to a new distinct supramolecular structure, Koji Oohora,Yoshitaka Onuma,Yuta Tanaka,Akira Onoda,Takashi Hayashi, Chemical Communications, Royal Society of Chemistry, Vol. 53, No. 51, p. 6879-6882, 2017
  • Iron-Strapped Porphyrins with Carboxylic Acid Groups Hanging over the Coordination Site: Synthesis, X-ray Characterization, and Dioxygen Binding, Boitrel, B.,Hijazi, I.,Roisnel, T.,Oohora, K.,Hayashi, T., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 56, No. 13, p. 7373-7383, 2017
  • Interdomain flip-flop motion visualized in flavocytochrome cellobiose dehydrogenase using high-speed atomic force microscopy during catalysis, Harada, H.,Onoda, A.,Uchihashi, T.,Watanabe, H.,Sunagawa, N.,Samejima, M.,Igarashi, K.,Hayashi, T., Chemical Science, ROYAL SOC CHEMISTRY, Vol. 8, No. 9, p. 6561-6565, 2017
  • CuAAC in a Distal Pocket: Metal Active-Template Synthesis of Strapped-Porphyrin [2]Rotaxanes, Miyazaki, Y.,Kahlfuss, C.,Ogawa, A.,Matsumoto, T.,Wytko, J.A.,Oohora, K.,Hayashi, T.,Weiss, J., Chemistry - A European Journal, WILEY-V C H VERLAG GMBH, Vol. 23, No. 55, p. 13579-13582, 2017
  • A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels–Alder Reaction, Himiyama, T.,Taniguchi, N.,Kato, S.,Onoda, A.,Hayashi, T., Angewandte Chemie - International Edition, WILEY-V C H VERLAG GMBH, Vol. 56, No. 44, p. 13618-13622, 2017
  • Catalytic Cyclopropanation by Myoglobin Reconstituted with Iron Porphycene: Acceleration of Catalysis due to Rapid Formation of the Carbene Species, Oohora, K.,Meichin, H.,Zhao, L.,Wolf, M.W.,Nakayama, A.,Hasegawa, J.-Y.,Lehnert, N.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 139, No. 48, p. 17265-17268, 2017
  • Cofactor-specific anchoring of horseradish peroxidase onto a polythiophene-modified electrode, Onoda, A.,Umeda, Y.,Hayashi, T., Chemistry Letters, CHEMICAL SOC JAPAN, Vol. 46, No. 12, p. 1818-1821, 2017
  • meso-tetraaryl(porphyrinato)cobalt(III)-catalyzed oxygenation of disilanes under aerobic conditions, Ohshita, J.,Matsumura, Y.,Nakayama, T.,Yoshida, H.,Kunai, A.,Hisaeda, Y.,Hayashi, T., Chemistry Letters, CHEMICAL SOC JAPAN, Vol. 46, No. 12, p. 1807-1809, 2017
  • Manganese(V) Porphycene Complex Responsible for Inert C-H Bond Hydroxylation in a Myoglobin Matrix, Oohora, K.,Meichin, H.,Kihira, Y.,Sugimoto, H.,Shiro, Y.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 139, No. 51, p. 18460-18463, 2017
  • Substitution of an amino acid residue axially coordinating to the heme molecule in hexameric tyrosine-coordinated hemoprotein to enhance peroxidase activity, Mashima, T.,Oohora, K.,Hayashi, T., Journal of Porphyrins and Phthalocyanines, World Scientific Publishing Co. Pte Ltd, Vol. 21, No. 12, p. 824-831, 2017
  • 5B35: Serial Femtosecond Crystallography (SFX) of Ground State Bacteriorhodopsin Crystallized from Bicelles Determined Using 7-keV X-ray Free Electron Laser (XFEL) at SACLA, Nakane T,Hanashima S,Suzuki M,Saiki H,Hayashi T,Kakinouchi K,Sugiyama S,Kawatake S,Matsuoka S,Matsumori N,Nango E,Kobayashi J,Shimamura T,Kimura K,Mori C,Kunishima N,Sugahara M,Takakyu Y,Inoue S,Masuda T,Hosaka T,Tono K,Joti Y,Kameshima T,Hatsui T,Yabashi M,Inoue T,Nureki O,Iwata S,Murata M,Mizohata E, Worldwide Protein Data Bank, 2016
  • Artificial Diels-Alderase based on the transmembrane protein FhuA, Osseili, H.,Sauer, D.F.,Beckerle, K.,Arlt, M.,Himiyama, T.,Polen, T.,Onoda, A.,Schwaneberg, U.,Hayashi, T.,Okuda, J., Beilstein Journal of Organic Chemistry, BEILSTEIN-INSTITUT, Vol. 12, p. 1314-1321, 2016
  • Crystal Structures and Coordination Behavior of Aqua- and Cyano-Co(III) Tetradehydrocorrins in the Heme Pocket of Myoglobin, Morita, Y.,Oohora, K.,Mizohata, E.,Sawada, A.,Kamachi, T.,Yoshizawa, K.,Inoue, T.,Hayashi, T., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 55, No. 3, p. 1287-1295, 2016
  • Intraprotein transmethylation via a CH<inf>3</inf>-Co(iii) species in myoglobin reconstituted with a cobalt corrinoid complex, Morita, Y.,Oohora, K.,Sawada, A.,Doitomi, K.,Ohbayashi, J.,Kamachi, T.,Yoshizawa, K.,Hisaeda, Y.,Hayashi, T., Dalton Transactions, ROYAL SOC CHEMISTRY, Vol. 45, No. 8, p. 3277-3284, 2016
  • Oxygen-binding Protein Fiber and Microgel: Supramolecular Myoglobin-Poly(acrylate) Conjugates, Ono, T.,Hisaoka, Y.,Onoda, A.,Oohora, K.,Hayashi, T., Chemistry - An Asian Journal, WILEY-V C H VERLAG GMBH, Vol. 11, No. 7, p. 1036-1042, 2016
  • Construction of a hybrid biocatalyst containing a covalently-linked terpyridine metal complex within a cavity of aponitrobindin, Himiyama, T.,Sauer, D.F.,Onoda, A.,Spaniol, T.P.,Okuda, J.,Hayashi, T., Journal of Inorganic Biochemistry, ELSEVIER SCIENCE INC, Vol. 158, p. 55-61, 2016
  • Photocatalytic Properties of TiO<inf>2</inf> Composites Immobilized with Gold Nanoparticle Assemblies Using the Streptavidin-Biotin Interaction, Harada, H.,Onoda, A.,Uematsu, T.,Kuwabata, S.,Hayashi, T., Langmuir, AMER CHEMICAL SOC, Vol. 32, No. 25, p. 6459-6467, 2016
  • Cofactor-specific covalent anchoring of cytochrome: B <inf>562</inf> on a single-walled carbon nanotube by click chemistry, Onoda, A.,Inoue, N.,Campidelli, S.,Hayashi, T., RSC Advances, ROYAL SOC CHEMISTRY, Vol. 6, No. 70, p. 65936-65940, 2016
  • Anchoring Cytochrome b<inf>562</inf>on a Gold Nanoparticle by a Heme–Heme Pocket Interaction, Onoda, A.,Taniguchi, T.,Inoue, N.,Kamii, A.,Hayashi, T., European Journal of Inorganic Chemistry, WILEY-V C H VERLAG GMBH, Vol. 2016, No. 21, p. 3454-3459, 2016
  • In Situ Observation of Enhanced Photoinduced Charge Separation in a Gold Nanoparticle Assembly Immobilized on TiO<inf>2</inf>, Harada, H.,Onoda, A.,Moriguchi, S.,Hayashi, T., ChemistrySelect, WILEY-V C H VERLAG GMBH, Vol. 1, No. 18, p. 5666-5670, 2016
  • Biohybrid catalysts constructed in a protein matrix with an artificial metal complex, Hayashi Takashi,Onoda Akira,Oohora Koji, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol. 250, 2015/08/16
  • Generation of new artificial metalloproteins by cofactor modification of native hemoproteins, Hayashi, T.,Sano, Y.,Onoda, A., Israel Journal of Chemistry, WILEY-V C H VERLAG GMBH, Vol. 55, No. 1, p. 76-84, 2015
  • Myoglobin-based non-precious metal carbon catalysts for an oxygen reduction reaction, Onoda, A.,Tanaka, Y.,Ono, T.,Takeuchi, S.,Sakai, A.,Hayashi, T., Journal of Porphyrins and Phthalocyanines, WORLD SCI PUBL CO INC, Vol. 19, No. 1-3, p. 510-516, 2015
  • Artificial hydrogenase: Biomimetic approaches controlling active molecular catalysts, Onoda, A.,Hayashi, T., Current Opinion in Chemical Biology, ELSEVIER SCI LTD, Vol. 25, p. 133-140, 2015
  • Meso-Dibenzoporphycene has a Large Bathochromic Shift and a Porphycene Framework with an Unusual cis Tautomeric Form, Oohora, K.,Ogawa, A.,Fukuda, T.,Onoda, A.,Hasegawa, J.-Y.,Hayashi, T., Angewandte Chemie - International Edition, WILEY-V C H VERLAG GMBH, Vol. 54, No. 21, p. 6227-6230, 2015
  • Energy migration within hexameric hemoprotein reconstituted with Zn porphyrinoid molecules, Oohora, K.,Mashima, T.,Ohkubo, K.,Fukuzumi, S.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 51, No. 55, p. 11138-11140, 2015
  • A Highly Active Biohybrid Catalyst for Olefin Metathesis in Water: Impact of a Hydrophobic Cavity in a β-Barrel Protein, Sauer, D.F.,Himiyama, T.,Tachikawa, K.,Fukumoto, K.,Onoda, A.,Mizohata, E.,Inoue, T.,Bocola, M.,Schwaneberg, U.,Hayashi, T.,Okuda, J., ACS Catalysis, AMER CHEMICAL SOC, Vol. 5, No. 12, p. 7519-7522, 2015
  • Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation, Herzog Konrad,Bracco Paula,Onoda Akira,Hayashi Takashi,Hoffmann Kurt,Schallmey Anett, ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, Vol. 70, p. 2875-2889, 2014/11
  • Catalytic alkane hydroxylation by myoglobin containing a manganese porphycene complex, Koji Oohora,Hiroyuki Meichin,Yushi Kihira,Takako Nishiura,Takashi Hayashi, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, SPRINGER, Vol. 19, p. S770-S771, 2014/08
  • Structure and function of heme-binding proteins in heme-uptake systems of gram-positive bacteria, Norifumi Muraki,Yasunori Okamoto,Takashi Hayashi,Shigetoshi Aono, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, SPRINGER, Vol. 19, p. S846-S847, 2014/08
  • Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation, Herzog, K.,Bracco, P.,Onoda, A.,Hayashi, T.,Hoffmann, K.,Schallmey, A., Acta Crystallographica Section D: Biological Crystallography, WILEY-BLACKWELL, Vol. 70, No. 11, p. 2875-2889, 2014
  • H<inf>2</inf>O<inf>2</inf>-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin, Okamoto, Y.,Onoda, A.,Sugimoto, H.,Takano, Y.,Hirota, S.,Kurtz, D.M.,Shiro, Y.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 50, No. 26, p. 3421-3423, 2014
  • Fabrication of enzyme-degradable and size-controlled protein nanowires using single particle nano-fabrication technique, Omichi, M.,Asano, A.,Tsukuda, S.,Takano, K.,Sugimoto, M.,Saeki, A.,Sakamaki, D.,Onoda, A.,Hayashi, T.,Seki, S., Nature Communications, NATURE PUBLISHING GROUP, Vol. 5, 2014
  • Rhodium-complex-linked hybrid biocatalyst: Stereo-controlled phenylacetylene polymerization within an engineered protein cavity, Fukumoto, K.,Onoda, A.,Mizohata, E.,Bocola, M.,Inoue, T.,Schwaneberg, U.,Hayashi, T., ChemCatChem, WILEY-V C H VERLAG GMBH, Vol. 6, No. 5, p. 1229-1235, 2014
  • Hemoprotein-based supramolecular assembling systems, Oohora, K.,Hayashi, T., Current Opinion in Chemical Biology, ELSEVIER SCI LTD, Vol. 19, No. 1, p. 154-161, 2014
  • Photochemical property of a myoglobin-CdTe quantum dot conjugate formed by supramolecular host-guest interactions, Himiyama, T.,Onoda, A.,Hayashi, T., Chemistry Letters, CHEMICAL SOC JAPAN, Vol. 43, No. 7, p. 1152-1154, 2014
  • Photoinduced hydrogen evolution catalyzed by a synthetic diiron dithiolate complex embedded within a protein matrix, Onoda, A.,Kihara, Y.,Fukumoto, K.,Sano, Y.,Hayashi, T., ACS Catalysis, AMER CHEMICAL SOC, Vol. 4, No. 8, p. 2645-2648, 2014
  • Co(II)/Co(I) reduction-induced axial histidine-flipping in myoglobin reconstituted with a cobalt tetradehydrocorrin as a methionine synthase model, Hayashi, T.,Morita, Y.,Mizohata, E.,Oohora, K.,Ohbayashi, J.,Inoue, T.,Hisaeda, Y., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 50, No. 83, p. 12560-12563, 2014
  • Heme-binding properties of HupD functioning as a substrate-binding protein in a heme-uptake ABC-transporter system in Listeria monocytogenes, Okamoto, Y.,Sawai, H.,Ogura, M.,Uchida, T.,Ishimori, K.,Hayashi, T.,Aono, S., Bulletin of the Chemical Society of Japan, CHEMICAL SOC JAPAN, Vol. 87, No. 10, p. 1140-1146, 2014
  • SACLAを利用したXFEL微結晶構造解析, 溝端栄一,鈴木守,南後恵理子,森田能次,垣之内啓介,田中里枝,登野健介,城地保昌,亀島敬,Jaehyun Park,Changyong Song,初井宇記,矢橋牧名,Thomas A White,北郷悠,大洞光司,石田英子,廣瀬未果,杉山成,村田道雄,林高史,高木淳一,井上豪,岩田想, 2013/10
  • Photoinduced electron transfer of ZnS-AgInS<inf>2</inf> solid-solution semiconductor nanoparticles: Emission quenching and photocatalytic reactions controlled by electrostatic forces, Uematsu, T.,Doko, A.,Torimoto, T.,Oohora, K.,Hayashi, T.,Kuwabata, S., Journal of Physical Chemistry C, Vol. 117, No. 30, p. 15667-15676, 2013
  • Supramolecular Linear Assemblies of Cytochrome b<inf>562</inf> Immobilized on a Gold Electrode, Kakikura, Y.,Onoda, A.,Kubo, E.,Kitagishi, H.,Uematsu, T.,Kuwabata, S.,Hayashi, T., Journal of Inorganic and Organometallic Polymers and Materials, SPRINGER, Vol. 23, No. 1, p. 172-179, 2013
  • Cathodic photocurrent generation from zinc-substituted cytochrome b <inf>562</inf> assemblies immobilized on an apocytochrome b<inf>562</inf>- modified gold electrode, Onoda, A.,Kakikura, Y.,Hayashi, T., Dalton Transactions, ROYAL SOC CHEMISTRY, Vol. 42, No. 45, p. 16102-16107, 2013
  • Complimenting a metal complex with protein environment toward a new hybrid biocatalyst, Onoda, A.,Hayashi, T., Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, SOC SYNTHETIC ORGANIC CHEM JPN, Vol. 71, No. 5, p. 452-460, 2013
  • Crystal structure, exogenous ligand binding, and redox properties of an engineered diiron active site in a bacterial hemerythrin, Okamoto, Y.,Onoda, A.,Sugimoto, H.,Takano, Y.,Hirota, S.,Kurtz, D.M.,Shiro, Y.,Hayashi, T., Inorganic Chemistry, Vol. 52, No. 22, p. 13014-13020, 2013
  • C(sp<sup>3</sup>)-H bond hydroxylation catalyzed by myoglobin reconstituted with manganese porphycene, Oohora, K.,Kihira, Y.,Mizohata, E.,Inoue, T.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 135, No. 46, p. 17282-17285, 2013
  • Erratum: An extremely long-lived singlet 4,4-dimethoxy-3,5- diphenylpyrazolidine-3,5-diyl derivative: A notable nitrogen-atom effect on intra- and intermolecular reactivity (Angewandte Chemie - International Edition (2006) 45 (7828-7831) DOI:10.1002/anie.200603287), Abe, M.,Kubo, E.,Nozaki, K.,Matsuo, T.,Hayashi, T., Angewandte Chemie - International Edition, Vol. 51, No. 48, p. 11924-11924, 2012
  • Creation of an artificial metalloprotein with a Hoveyda–Grubbs catalyst moiety through the intrinsic inhibition mechanism of α-chymotrypsin, Matsuo, T.,Imai, C.,Yoshida, T.,Saito, T.,Hayashi, T.,Hirota, S., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 48, No. 11, p. 1662-1664, 2012
  • Photocatalytic hydrogen evolution by a diiron hydrogenase model based on a peptide fragment of cytochrome c <inf>556</inf> with an attached diiron carbonyl cluster and an attached ruthenium photosensitizer, Sano, Y.,Onoda, A.,Hayashi, T., Journal of Inorganic Biochemistry, ELSEVIER SCIENCE INC, Vol. 108, p. 159-162, 2012
  • Photocurrent generation from hierarchical zinc-substituted hemoprotein assemblies immobilized on a gold electrode, Onoda, A.,Kakikura, Y.,Uematsu, T.,Kuwabata, S.,Hayashi, T., Angewandte Chemie - International Edition, WILEY-V C H VERLAG GMBH, Vol. 51, No. 11, p. 2628-2631, 2012
  • Chemically programmed supramolecular assembly of hemoprotein and streptavidin with alternating alignment, Oohora, K.,Burazerovic, S.,Onoda, A.,Wilson, Y.M.,Ward, T.R.,Hayashi, T., Angewandte Chemie - International Edition, WILEY-V C H VERLAG GMBH, Vol. 51, No. 16, p. 3818-3821, 2012
  • Reaction of cobalt porphycene with hydride reagents: Spectroscopic detection of Co-H porphycene species and formation of Co-SnR<inf>3</inf> porphycene species, Matsuo, T.,Komatsuzaki, K.,Tsuji, T.,Hayashi, T., Journal of Porphyrins and Phthalocyanines, WORLD SCI PUBL CO INC, Vol. 16, No. 5-6, p. 616-625, 2012
  • Photochemical properties of a myoglobin-CdTe quantum dot conjugate, Onoda, A.,Himiyama, T.,Ohkubo, K.,Fukuzumi, S.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 48, No. 65, p. 8054-8056, 2012
  • A rhodium complex-linked β-barrel protein as a hybrid biocatalyst for phenylacetylene polymerization, Onoda, A.,Fukumoto, K.,Arlt, M.,Bocola, M.,Schwaneberg, U.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 48, No. 78, p. 9756-9758, 2012
  • Fibrous supramolecular hemoprotein assemblies connected with synthetic heme dimer and apohemoprotein dimer, Onoda, A.,Takahashi, A.,Oohora, K.,Onuma, Y.,Hayashi, T., Chemistry and Biodiversity, WILEY-V C H VERLAG GMBH, Vol. 9, No. 9, p. 1684-1692, 2012
  • Reaction pathway and free energy profile for conversion of π-conjugation modes in porphyrin isomer, Matsuo, T.,Tohi, Y.,Hayashi, T., Journal of Organic Chemistry, AMER CHEMICAL SOC, Vol. 77, No. 20, p. 8946-8955, 2012
  • Supramolecular assembling systems formed by heme–heme pocket interactions in hemoproteins, Oohora, K.,Onoda, A.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 48, No. 96, p. 11714-11726, 2012
  • Preparation and reactivity of a tetranuclear Fe(II) core in the metallothionein α-domain, Sano, Y.,Onoda, A.,Sakurai, R.,Kitagishi, H.,Hayashi, T., Journal of Inorganic Biochemistry, ELSEVIER SCIENCE INC, Vol. 105, No. 5, p. 702-708, 2011
  • Thermal isomerization of N-bridged cobalt corrole complexes through a transiently formed axial carbenoid, Chattopadhyay, P.,Matsuo, T.,Tsuji, T.,Ohbayashi, J.,Hayashi, T., Organometallics, AMER CHEMICAL SOC, Vol. 30, No. 7, p. 1869-1873, 2011
  • Investigation of aromaticity and photophysical properties in [18]/[20]π porphycene derivatives, Kim, K.S.,Sung, Y.M.,Matsuo, T.,Hayashi, T.,Kim, D., Chemistry - A European Journal, WILEY-BLACKWELL, Vol. 17, No. 28, p. 7882-7889, 2011
  • Precise design of artificial cofactors for enhancing peroxidase activity of myoglobin: Myoglobin mutant H64D reconstituted with a "single-winged cofactor" Is equivalent to native horseradish peroxidase in oxidation activity, Matsuo, T.,Fukumoto, K.,Watanabe, T.,Hayashi, T., Chemistry - An Asian Journal, WILEY-V C H VERLAG GMBH, Vol. 6, No. 9, p. 2491-2499, 2011
  • A chemically-controlled supramolecular protein polymer formed by a myoglobin-based self-assembly system, Oohora, K.,Onoda, A.,Kitagishi, H.,Yamaguchi, H.,Harada, A.,Hayashi, T., Chemical Science, ROYAL SOC CHEMISTRY, Vol. 2, No. 6, p. 1033-1038, 2011
  • Crystal structure and spectroscopic studies of a stable mixed-valent state of the hemerythrin-like domain of a bacterial chemotaxis protein, Onoda, A.,Okamoto, Y.,Sugimoto, H.,Shiro, Y.,Hayashi, T., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 50, No. 11, p. 4892-4899, 2011
  • A hydrogenase model system based on the sequence of cytochrome c: Photochemical hydrogen evolution in aqueous media, Sano, Y.,Onoda, A.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 47, No. 29, p. 8229-8231, 2011
  • 1SE0920 Molecular Mechanism of Water Expelling System in the Initial Step of Cytochrome P450cam Catalytic Cycle(1SE Recent Advances in Structural Analyses of Funcitonal Mechanisms Based on Dynamics of Biological Reactions,The 48th Annual Meeting of the Biophysical Society of Japan), Hayashi Takashi, Seibutsu Butsuri, The Biophysical Society of Japan General Incorporated Association, Vol. 50, No. 2, 2010
  • DNA-binding hemoproteins tethering polyamine interface, Onoda, A.,Nagai, H.,Koga, S.,Hayashi, T., Bulletin of the Chemical Society of Japan, CHEMICAL SOC JAPAN, Vol. 83, No. 4, p. 375-377, 2010
  • Supramolecular hemoprotein-gold nanoparticle conjugates, Onoda, A.,Ueya, Y.,Sakamoto, T.,Uematsu, T.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 46, No. 48, p. 9107-9109, 2010
  • Supramolecular protein-protein complexation via specific interaction between glycosylated myoglobin and sugar-binding protein, Nagai, H.,Onoda, A.,Matsuo, T.,Hayashi, T., Supramolecular Chemistry, TAYLOR & FRANCIS LTD, Vol. 22, No. 1, p. 57-64, 2010
  • Thermodynamically controlled supramolecular polymerization of cytochrome b<inf>562</inf>, Kitagishi, H.,Oohora, K.,Hayashi, T., Biopolymers, WILEY-BLACKWELL, Vol. 91, No. 3, p. 194-200, 2009
  • Substrate binding induces structural changes in cytochrome P450cam, Sakurai, K.,Shimada, H.,Hayashi, T.,Tsukihara, T., Acta Crystallographica Section F: Structural Biology and Crystallization Communications, WILEY-BLACKWELL PUBLISHING, INC, Vol. 65, No. 2, p. 80-83, 2009
  • Self-assembly of one- And two-dimensional hemoprotein systems by polymerization through heme-heme pocket interactions, Kitagishi, H.,Kakikura, Y.,Yamaguchi, H.,Oohora, K.,Harada, A.,Hayashi, T., Angewandte Chemie - International Edition, WILEY-V C H VERLAG GMBH, Vol. 48, No. 7, p. 1271-1274, 2009
  • A role of the heme-7-propionate side chain in cytochrome P450cam as a gate for regulating the access of water molecules to the substrate-binding site, Hayashi, T.,Harada, K.,Sakurai, K.,Shimada, H.,Hirota, S., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 131, No. 4, p. 1398-+, 2009
  • Meso-unsubstituted iron corrole in hemoproteins: Remarkable differences in effects on peroxidase activities between myoglobin and horseradish peroxidase, Matsuo, T.,Hayashi, A.,Abe, M.,Matsuda, T.,Hisaeda, Y.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 131, No. 42, p. 15124-+, 2009
  • Electron transfer and oxidase activities in reconstituted hemoproteins with chemically modified cofactors, Matsuo, T.,Hayashi, T., Journal of Porphyrins and Phthalocyanines, WORLD SCI PUBL CO INC, Vol. 13, No. 10, p. 1082-1089, 2009
  • Roles of heme-6-propionate side chain in monooxygenase cytochrome P450cam, Sakurai Keisuke,Harada Katsuyoshi,Shimada Hideo,Hayashi Takashi, ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, Vol. 64, 2008
  • Oxidation reactivities of reconstituted hemoproteins with non-natural porphyrinoid cofactors, Takashi Matsuo,Michiko Fujii,Masato Abe,Dai Murata,Takashi Hayashi, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, PHARMACEUTICAL SOC JAPAN, Vol. 128, p. 49-49, 2008
  • A supramolecular receptor of diatomic molecules (O<inf>2</inf>, CO, NO) in aqueous solution, Kano, K.,Itoh, Y.,Kitagishi, H.,Hayashi, T.,Hirota, S., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 130, No. 25, p. 8006-8015, 2008
  • Photocatalytic hydrogen generation using a protein-coated photosensitizer with anionic patches and a monocationic electron mediator, Matsuo, T.,Asano, A.,Ando, T.,Hisaeda, Y.,Hayashi, T., Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 3684-3686, No. 31, p. 3684-3686, 2008
  • Isolable iron(II)-porphycene derivative stabilized by introduction of trifluoromethyl groups on the ligand framework, Ito, K.,Matsuo, T.,Aritome, I.,Hisaeda, Y.,Hayashi, T., Bulletin of the Chemical Society of Japan, CHEMICAL SOC JAPAN, Vol. 81, No. 1, p. 76-83, 2008
  • Effect of peripheral trifluoromethyl groups in artificial iron porphycene cofactor on ligand binding properties of myoglobin, Matsuo, T.,Ito, K.,Nakashima, Y.,Hisaeda, Y.,Hayashi, T., Journal of Inorganic Biochemistry, ELSEVIER SCIENCE INC, Vol. 102, No. 2, p. 166-173, 2008
  • Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam, Harada, K.,Sakurai, K.,Ikemura, K.,Ogura, T.,Hirota, S.,Shimada, H.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 130, No. 2, p. 432-+, 2008
  • Exo-selective formation of bicyclic oxetanes in the photocycloaddition reaction of carbonyl compounds with vinylene carbonate: The important role of intermediary triplet diradicals in the stereoselectivity, Abe, M.,Taniguchi, K.,Hayashi, T., Arkivoc, Vol. 2007, No. 8, p. 58-65, 2007
  • Porphyrinoid chemistry in hemoprotein matrix: Detection and reactivities of iron(IV)-oxo species of porphycene incorporated into horseradish peroxidase, Matsuo, T.,Murata, D.,Hisaeda, Y.,Hori, H.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 129, No. 43, p. 12906-+, 2007
  • A structural isomer of nonaromatic porphyrin: Preparation of 20π-conjugated porphycene based on electronic perturbation, Matsuo, T.,Ito, K.,Kanehisa, N.,Hayashi, T., Organic Letters, AMER CHEMICAL SOC, Vol. 9, No. 25, p. 5303-5306, 2007
  • Supramolecular hemoprotein linear assembly by successive interprotein heme-heme pocket interactions, Kitagishi, H.,Oohora, K.,Yamaguchi, H.,Sato, H.,Matsuo, T.,Harada, A.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 129, No. 34, p. 10326-+, 2007
  • Structure and ligand binding properties of myoglobins reconstituted with monodepropionated heme: Functional role of each heme propionate side chain, Harada, K.,Makino, M.,Sugimoto, H.,Hirota, S.,Matsuo, T.,Shiro, Y.,Hisaeda, Y.,Hayashi, T., Biochemistry, AMER CHEMICAL SOC, Vol. 46, No. 33, p. 9406-9416, 2007
  • 鉄を含むタンパク質 : その多様な構造と反応性(ヘッドライン:生物無機化学-生体の中で働く金属イオンの化学-), 松尾 貴史,林 高史, 化学と教育, 公益社団法人 日本化学会, Vol. 54, No. 9, p. 474-477, 2006
  • Notable temperature effect on the stereoselectivity in the photochemical [2+2] cycloaddition reaction (Paternò-Büchi reaction) of 2,3-dihydrofuran-3-ol derivatives with benzophenone, Abe, M.,Terazawa, M.,Nozaki, K.,Masuyama, A.,Hayashi, T., Tetrahedron Letters, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 47, No. 15, p. 2527-2530, 2006
  • Construction of glycosylated myoglobin by reconstitutional method, Matsuo, T.,Nagai, H.,Hisaeda, Y.,Hayashi, T., Chemical Communications, Royal Society of Chemistry (RSC), Vol. 3131-3133, No. 29, p. 3131-3131, 2006
  • Experimental probe for hyperconjugative resonance contribution in stabilizing the singlet state of 2,2-dialkoxy-1,3-diyls: Regioselective 1,2-oxygen migration, Abe, M.,Hattori, M.,Takegami, A.,Masuyama, A.,Hayashi, T.,Seki, S.,Tagawa, S., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 128, No. 24, p. 8008-8014, 2006
  • A matrix isolation study of 2-isopropylidenecyclopentane-1,3-diyl (Berson-type diradical), Abe, M.,Kawanami, S.,Masuyama, A.,Hayashi, T., Journal of Organic Chemistry, AMER CHEMICAL SOC, Vol. 71, No. 17, p. 6607-6610, 2006
  • An extremely long-lived singlet 4,4-dimethoxy-3,5-diphenylpyrazolidine-3,5- diyl derivative: A notable nitrogen-atom effect on intra- and intermolecular reactivity, Abe, M.,Kubo, E.,Nozaki, K.,Matsuo, T.,Hayashi, T., Angewandte Chemie - International Edition, WILEY-V C H VERLAG GMBH, Vol. 45, No. 46, p. 7828-7831, 2006
  • Pathway of information transmission from heme to protein upon ligand binding/dissociation in myoglobin revealed by UV resonance raman spectroscopy, Gao, Y.,El-Mashtoly, S.F.,Pal, B.,Hayashi, T.,Harada, K.,Kitagawa, T., Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 281, No. 34, p. 24637-24646, 2006
  • Time-resolved Raman evidence for energy 'funneling' through propionate side chains in heme 'cooling' upon photolysis of carbonmonoxy myoglobin, Gao, Y.,Koyama, M.,El-Mashtoly, S.F.,Hayashi, T.,Harada, K.,Mizutani, Y.,Kitagawa, T., Chemical Physics Letters, ELSEVIER SCIENCE BV, Vol. 429, No. 1-3, p. 239-243, 2006
  • Crystal structure and peroxidase activity of myoglobin reconstituted with iron porphycene, Hayashi, T.,Murata, D.,Makino, M.,Sugimoto, H.,Matsuo, T.,Sato, H.,Shiro, Y.,Hisaeda, Y., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 45, No. 26, p. 10530-10536, 2006
  • Organic/inorganic hybrid nanomaterials with vitamin B<inf>12</inf> functions, Hisaeda, Y.,Masuko, T.,Hanashima, E.,Hayashi, T., Science and Technology of Advanced Materials, NATL INST MATERIALS SCIENCE, Vol. 7, No. 7, p. 655-661, 2006
  • Ligand binding properties of two kinds of reconstituted myoglobins with iron porphycene having propionates: Effect of β-pyrrolic position of two propionate side chains in porphycene framework, Matsuo, T.,Ikegami, T.,Sato, H.,Hisaeda, Y.,Hayashi, T., Journal of Inorganic Biochemistry, ELSEVIER SCIENCE INC, Vol. 100, No. 7, p. 1265-1271, 2006
  • Iron porphyrin-cyclodextrin supramolecular complex as a functional model of myoglobin in aqueous solution, Kano, K.,Kitagishi, H.,Dagallier, C.,Kodera, M.,Matsuo, T.,Hayashi, T.,Hisaeda, Y.,Hirota, S., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 45, No. 11, p. 4448-4460, 2006
  • Functionalization of myoglobin, Watanabe, Y.,Hayashi, T., Progress in Inorganic Chemistry, Progress in Inorganic Chemistry, Vol. 54, p. 449-493, 2005
  • Preparation and O<inf>2</inf> binding study of myoglobin having a cobalt porphycene, Matsuo, T.,Tsuruta, T.,Maehara, K.,Sato, H.,Hisaeda, Y.,Hayashi, T., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 44, No. 25, p. 9391-9396, 2005
  • Unusual ligand discrimination by a myoglobin reconstituted with a hydrophobic domain-linked heme, Sato, H.,Watanabe, M.,Hisaeda, Y.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 127, No. 1, p. 56-57, 2005
  • Chemical properties of sperm whale myoglobins reconstituted with monopropionate hemins, Hayashi, T.,Nakagawa, T.,Harada, K.,Matsuo, T.,Hitomi, Y.,Hisaeda, Y., Chemistry Letters, CHEMICAL SOC JAPAN, Vol. 33, No. 11, p. 1512-1513, 2004
  • Ligand binding properties of myoglobin reconstituted with iron porphycene: Unusual O<inf>2</inf> binding selectivity against CO binding, Matsuo, T.,Dejima, H.,Hirota, S.,Murata, D.,Sato, H.,Ikegami, T.,Hori, H.,Hisaeda, Y.,Hayashi, T., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 126, No. 49, p. 16007-16017, 2004
  • Residues in the distal heme pocket of neuroglobin: Implications for the multiple ligand binding steps, Uno, T.,Ryu, D.,Tsutsumi, H.,Tomisugi, Y.,Ishikawa, Y.,Wilkinson, A.J.,Sato, H.,Hayashi, T., Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 279, No. 7, p. 5886-5893, 2004
  • Hybridization of Modified-Heme Reconstitution and Distal Histidine Mutation to Functionalize Sperm Whale Myoglobin, Sato, H.,Hayashi, T.,Ando, T.,Hisaeda, Y.,Ueno, T.,Watanabe, Y., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 126, No. 2, p. 436-437, 2004
  • Laser heating dynamics of poly(methyl methacrylate) films doped with aromatic molecules as revealed by analysis of diffusion of triplet states, Fujiwara, H.,Ishii, H.,Ishiwata, T.,Hayashi, T.,Fukumura, H.,Masuhara, H., Bulletin of the Chemical Society of Japan, Vol. 76, No. 5, 2003
  • Synthesis, Characterization, and Autoreduction of a Highly Electron-Deficient Porphycenatoiron(III) with Trifluoromethyl Substituents, Hayashi, T.,Nakashima, Y.,Ito, K.,Ikegami, T.,Aritome, I.,Aoyagi, K.,Ando, T.,Hisaeda, Y., Inorganic Chemistry, AMER CHEMICAL SOC, Vol. 42, No. 23, p. 7345-7347, 2003
  • Synthesis, structure, and chemical property of the first fluorine-containing porphycene, Hayashi, T.,Nakashima, Y.,Ito, K.,Ikegami, T.,Aritome, I.,Suzuki, A.,Hisaeda, Y., Organic Letters, AMER CHEMICAL SOC, Vol. 5, No. 16, p. 2845-2848, 2003
  • Enhancement of peroxygenase activity of horse heart myoglobin by modification of heme-propionate side chains, Hayashi, T.,Matsuda, T.,Hisaeda, Y., Chemistry Letters, CHEMICAL SOC JAPAN, Vol. 32, No. 6, p. 496-497, 2003
  • Iron twin-coronet porphyrins as models of myoglobin and hemoglobin: Amphibious electrostatic effects of overhanging hydroxyl groups for successful CO/O<inf>2</inf> discrimination, Tani, F.,Matsu-ura, M.,Ariyama, K.,Setoyama, T.,Shimada, T.,Kobayashi, S.,Hayashi, T.,Matsuo, T.,Hisaeda, Y.,Naruta, Y., Chemistry - A European Journal, WILEY-V C H VERLAG GMBH, Vol. 9, No. 4, p. 862-870, 2003
  • Reductive activation of dioxygen by a myoglobin reconstituted with a flavohemin, Matsuo, T.,Hayashi, T.,Hisaeda, Y., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 124, No. 38, p. 11234-11235, 2002
  • Blue myoglobin reconstituted with an iron porphycene shows extremely high oxygen affinity, Hayashi, T.,Dejima, H.,Matsuo, T.,Sato, H.,Murata, D.,Hisaeda, Y., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 124, No. 38, p. 11226-11227, 2002
  • Conversion of hemoprotein function by chemical modification, Hayashi, T., Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, Society of Synthetic Organic Chemistry, Vol. 60, No. 6, p. 573-580, 2002
  • Contribution of heme-propionate side chains to structure and function of myoglobin: chemical approach by artificially created prosthetic groups, Hayashi, T.,Matsuo, T.,Hitomi, Y.,Okawa, K.,Suzuki, A.,Shiro, Y.,Iizuka, T.,Hisaeda, Y.,Ogoshi, H., Journal of Inorganic Biochemistry, ELSEVIER SCIENCE INC, Vol. 91, No. 1, p. 94-100, 2002
  • Chiral recognition and chiral sensing using zinc porphyrin dimers, Hayashi, T.,Aya, T.,Nonoguchi, M.,Mizutani, T.,Hisaeda, Y.,Kitagawa, S.,Ogoshi, H., Tetrahedron, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 58, No. 14, p. 2803-2811, 2002
  • New functionalization of myoglobin by chemical modification of heme-propionates, Hayashi, T.,Hisaeda, Y., Accounts of Chemical Research, AMER CHEMICAL SOC, Vol. 35, No. 1, p. 35-43, 2002
  • Electroorganic syntheses of macrocyclic lactones mediated by vitamin B-12 model complexes Part 17. Hydrophobic vitamin B-12, Shimakoshi H,Nakazato A,Hayashi T,Tachi Y,Naruta Y,Hisaeda Y, JOURNAL OF ELECTROANALYTICAL CHEMISTRY, Vol. 507, No. 1-2, p. 170-176, 2001/07/13
  • Interprotein Electron Transfer Reaction Regulated by an Artificial Interface We thank Prof. Dr. I. Morishima and his group for the arrangement of laser flash photolysis equipment. This work was supported by Nagase Science and Technology Foundation, and a Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture, Japan. Y. H. was supported by Research Fellowships of the Japanese Society for the Promotion of Science for Young Scientists., Yutaka Hitomi,Takashi Hayashi,Kenji Wada,Tadashi Mizutani,Yoshio Hisaeda,Hisanobu Ogoshi, Angewandte Chemie (International ed. in English), Vol. 40, No. 6, p. 1098-1101, 2001/03/16
  • Electroorganic syntheses of macrocyclic lactones mediated by vitamin B<inf>12</inf> model complexes: Part 17. Hydrophobic vitamin B<inf>12</inf>, Shimakoshi, H.,Nakazato, A.,Hayashi, T.,Tachi, Y.,Naruta, Y.,Hisaeda, Y., Journal of Electroanalytical Chemistry, ELSEVIER SCIENCE SA, Vol. 507, No. 1-2, p. 170-176, 2001
  • Cobaltporphycenes as catalysts. The oxidation of vinyl ethers via the formation and dissociation of cobalt-carbon bonds, Hayashi, T.,Okazaki, K.,Urakawa, N.,Shimakoshi, H.,Sessler, J.L.,Vogel, E.,Hisaeda, Y., Organometallics, AMER CHEMICAL SOC, Vol. 20, No. 14, p. 3074-3078, 2001
  • Formation and cleavage of a dicobalt complex bridged with a pentamethylene group, Shimakoshi, H.,Koga, M.,Hayashi, T.,Tachi, Y.,Naruta, Y.,Hisaeda, Y., Chemistry Letters, Chemical Society of Japan, No. 4, p. 346-347, 2001
  • Interprotein electron transfer reaction regulated by an artificial interface, Hitomi, Y.,Hayashi, T.,Wada, K.,Mizutani, T.,Hisaeda, Y.,Ogoshi, H., Angewandte Chemie - International Edition, WILEY-V C H VERLAG GMBH, Vol. 40, No. 6, p. 1098-+, 2001
  • Electrochemical reactions mediated by vitamin B<inf>12</inf> derivatives in organic solvents, Hisaeda, Y.,Nishioka, T.,Inoue, Y.,Asada, K.,Hayashi, T., Coordination Chemistry Reviews, Elsevier, Vol. 198, No. 1, p. 21-37, 2000
  • Introduction of a specific binding domain on myoglobin surface by new chemical modification, Hayashi, T.,Ando, T.,Matsuda, T.,Yonemura, H.,Yamada, S.,Hisaeda, Y., Journal of Inorganic Biochemistry, ELSEVIER SCIENCE INC, Vol. 82, No. 1-4, p. 133-139, 2000
  • Synthesis and properties of alkylperoxocobalt(III) porphyrin and porphycene, Hayashi, T.,Okazaki, K.,Shimakoshi, H.,Tani, F.,Naruta, Y.,Hisaeda, Y., Chemistry Letters, Chemical Society of Japan, No. 2, p. 90-91, 2000
  • Enhancement of peroxidase activity by use of reconstituted myoglobin, T Hayashi,Y Hitomi,Y Hisaeda,S Kitagawa, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 74, No. 1-4, p. 156-156, 1999/04
  • Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: Donor sugar-nucleotide based approach, S Takayama,SJ Chung,Y Igarashi,Y Ichikawa,A Sepp,RI Lechler,JY Wu,T Hayashi,G Siuzdak,CH Wong, BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 7, No. 2, p. 401-409, 1999/02
  • New approach to the construction of an artificial hemoprotein complex, Hayashi, T.,Hitomi, Y.,Takimura, T.,Tomokuni, A.,Mizutani, T.,Hisaeda, Y.,Ogoshi, H., Coordination Chemistry Reviews, Vol. 190-192, p. 961-974, 1999
  • Peroxidase activity of myoglobin is enhanced by chemical mutation of heme-propionates, Hayashi, T.,Hitomi, Y.,Ando, T.,Mizutani, T.,Hisaeda, Y.,Kitagawa, S.,Ogoshi, H., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 121, No. 34, p. 7747-7750, 1999
  • Synthesis and structure of tetraols with convergent and divergent arrays of hydroxy groups, Takagi, H.,Hayashi, T.,Mizutani, T.,Masuda, H.,Ogoshi, H., Journal of the Chemical Society - Perkin Transactions 1, Royal Society of Chemistry, No. 13, p. 1885-1892, 1999
  • Structure and reactivity of reconstituted myoglobins: Interaction between protein and polar side chain of chemically modified hemin, Hayashi, T.,Takimura, T.,Aoyama, Y.,Hitomi, Y.,Suzuki, A.,Ogoshi, H., Inorganica Chimica Acta, ELSEVIER SCIENCE SA, Vol. 275-276, No. 1-2, p. 159-167, 1998
  • Molecular recognition by novel macrotetracyclic cyclophanes having dipeptide segments, Tanaka, A.,Shimada, S.,Hirohashi, T.,Hayashi, T.,Hisaeda, Y., Chemistry Letters, Chemical Society of Japan, No. 11, p. 1109-1110, 1998
  • Interfacial recognition between reconstituted myoglobin having charged binding domain and electron acceptor via electrostatic interaction, Hayashi, T.,Tomokuni, A.,Mizutani, T.,Hisaeda, Y.,Ogoshi, H., Chemistry Letters, Chemical Society of Japan, No. 12, p. 1229-1230, 1998
  • Kinetic and thermodynamic analysis of induced-fit molecular recognition between tetraarylporphyrin and ubiquinone analogues, Hayashi, T.,Asai, T.,Borgmeier, F.M.,Hokazono, H.,Ogoshi, H., Chemistry - A European Journal, Vol. 4, No. 7, p. 1266-1274, 1998
  • Artificial protein-protein complexation between a reconstituted myoglobulin and cytochrome c, Hayashi, T.,Hitomi, Y.,Ogoshi, H., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 120, No. 20, p. 4910-4915, 1998
  • A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)galactose and evaluation of its interaction with galactosyltransferase, T Hayashi,BW Murray,R Wang,CH Wong, BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 5, No. 3, p. 497-500, 1997/03
  • Molecular modelling of electron transfer systems by noncovalently linked porphyrin-acceptor pairing, Hayashi, T.,Ogoshi, H., Chemical Society Reviews, ROYAL SOC CHEMISTRY, Vol. 26, No. 5, p. 355-364, 1997
  • Molecular recognition of ubiquinone analogues. Specific interaction between quinone and functional porphyrin via multiple hydrogen bonds, Hayashi, T.,Miyahara, T.,Koide, N.,Kato, Y.,Masuda, H.,Ogoshi, H., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 119, No. 31, p. 7281-7290, 1997
  • Solvent effects on thermodynamic parameters for porphyrin-quinone interaction through multiple hydrogen bonding, Hayashi, T.,Miyahara, T.,Koide, N.,Ogoshi, H., Chemical Communications, Royal Society of Chemistry, No. 19, p. 1865-1866, 1997
  • Conformational analysis of β-turn structure in tetrapeptides containing proline or proline analogs, Hayashi, T.,Asai, T.,Ogoshi, H., Tetrahedron Letters, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 38, No. 17, p. 3039-3042, 1997
  • Molecular recognition of α,ω-diamines by metalloporphyrin dimer, Hayashi, T.,Nonoguchi, M.,Aya, T.,Ogoshi, H., Tetrahedron Letters, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 38, No. 9, p. 1603-1606, 1997
  • Photoinduccd electron transfer between multifunctional porphyrin and ubiquinone analogues linked by several hydrogen-bonding interactions, Hayashi, T.,Miyahara, T.,Kumazaki, S.,Ogoshi, H.,Yoshihara, K., Angewandte Chemie (International Edition in English), Wiley-VCH Verlag, Vol. 35, No. 17, p. 1964-1966, 1996
  • Synthesis of ring-fluorinated porphyrins and reconstitutional myoglobins with their iron complexes, Suzuki, A.,Tomizawa, T.,Hayashi, T.,Mizutani, T.,Ogoshi, H., Bulletin of the Chemical Society of Japan, CHEMICAL SOC JAPAN, Vol. 69, No. 10, p. 2923-2933, 1996
  • Synthetic strategies of multifunctional porphyrins as receptors, Ogoshi, H.,Kuroda, Y.,Mizutani, T.,Hayashi, T., Pure and Applied Chemistry, Walter de Gruyter GmbH, Vol. 68, No. 7, p. 1411-1415, 1996
  • Anion complexation by bidentate Lewis acidic hosts, ortho-bis(fluorosilyl) benzenes, Tamao, K.,Hayashi, T.,Ito, Y., Journal of Organometallic Chemistry, ELSEVIER SCIENCE SA LAUSANNE, Vol. 506, No. 1-2, p. 85-91, 1996
  • MOLECULAR RECOGNITION OF HORSE HEART APOMYOGLOBIN TO MONOPROPIONATE HEMIN - THERMODYNAMIC DETERMINATION OF 2 ORIENTATIONAL ISOMERS BY H-1-NMR SPECTRA, T HAYASHI,Y HITOMI,A SUZUKI,T TAKIMURA,H OGOSHI, CHEMISTRY LETTERS, CHEMICAL SOC JAPAN, No. 10, p. 911-912, 1995/10
  • Silicon-carbon bond cleavage of pentacoordinate anionic silicates by N-bromosuccinimide, Tamao, K.,Hayashi, T.,Ito, Y., Bulletin de la Societe Chimique de France, EDITIONS SCIENTIFIQUES ELSEVIER, Vol. 132, No. 5-6, p. 556-558, 1995
  • Photoinduced electron transfer from zinc porphyrin to a linked quinone in myoglobin, Hayashi, T.,Takimura, T.,Ohara, T.,Hitomi, Y.,Ogoshi, H., Journal of the Chemical Society, Chemical Communications, ROYAL SOC CHEMISTRY, No. 24, p. 2503-2504, 1995
  • Photoinduced Singlet Electron Transfer in a Complex Formed from Zinc Myoglobin and Methyl Viologen: Artificial Recognition by a Chemically Modified Porphyrin, Hayashi, T.,Takimura, T.,Ogoshi, H., Journal of the American Chemical Society, Vol. 117, No. 46, p. 11606-11607, 1995
  • Molecular Recognition of Horse Heart Apomyoglobin for Monopropionate Hemin : Thermodynamic Determiuation of Two Orientational Isowers by <sup>1</sup>H NMR Spectra, Chem, Lett., No. 10, p. 911-912, 1995
  • Relationship between electron transfer and the structure of a quinone-linked zinc porphyrin with a flexible peptide spacer, Hayashi, T.,Takimura, T.,Hitomi, Y.,Ohara, T.,Ogoshi, H., Journal of the Chemical Society, Chemical Communications, ROYAL SOC CHEMISTRY, No. 5, p. 545-546, 1995
  • PREPARATION AND BINDING-AFFINITY OF NEW PORPHYRIN HOST MOLECULE FOR UBIQUINONE ANALOGS, T HAYASHI,T MIYAHARA,Y AOYAMA,M NONOGUCHI,H OGOSHI, CHEMISTRY LETTERS, CHEMICAL SOC JAPAN, No. 9, p. 1749-1752, 1994/09
  • Intermolecular interaction between multifunctional porphyrin and ubiquinone analogues, Hayashi, T.,Miyahara, T.,Aoyama, Y.,Kobayashi, M.,Ogoshi, H., Pure and Applied Chemistry, Vol. 66, No. 4, p. 797-802, 1994
  • Carbene insertion into oxygenhydrogen bonds by metalloporphyrin catalysts, Hayashi, T.,Kato, T.,Kaneko, T.,Asai, T.,Ogoshi, H., Journal of Organometallic Chemistry, ELSEVIER SCIENCE SA LAUSANNE, Vol. 473, No. 1-2, p. 323-327, 1994
  • Synthesis and structure of a new cis-1,3-dihydroxycyclohexane derivative having four convergent hydroxy groups, Hayashi, T.,Takagi, H.,Masuda, H.,Ogoshi, H., Journal of the Chemical Society, Chemical Communications, ROYAL SOC CHEMISTRY, No. 4, p. 364-365, 1993
  • Specific Molecular Recognition via Multipoint Hydrogen Bonding Ubiquinone Analogues—Porphyrin Having Four Convergent Hydroxyl Groups Pairing, Hayashi, T.,Miyahara, T.,Hashizume, N.,Ogoshi, H., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 115, No. 5, p. 2049-2051, 1993
  • Dynamic Molecular Recognition in a Multifunctional Porphyrin and a Ubiquinone Analogue, Hayashi, T.,Asai, T.,Hokazono, H.,Ogoshi, H., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 115, No. 25, p. 12210-12211, 1993
  • Pentacoordinate Anionic Bis(siliconates) Containing a Fluorine Bridge between Two Silicon Atoms. Synthesis, Solid-State Structures, and Dynamic Behavior in Solution, Tamao, K.,Hayashi, T.,Ito, Y.,Shiro, M., Organometallics, AMER CHEMICAL SOC, Vol. 11, No. 6, p. 2099-2114, 1992
  • Electronic and Steric Effects in Pentacoordinate Anioni Diorganotrifluorosilicates: X-ray Structures and <sup>13</sup>C NMR Studies for Evaluation of Charge Distribution in Aryl Groups on Silicon, Tamao, K.,Hayashi, T.,Ito, Y.,Shiro, M., Organometallics, AMER CHEMICAL SOC, Vol. 11, No. 1, p. 182-191, 1992
  • HYDROGEN-PEROXIDE OXIDATION OF THE SILICON-CARBON BOND - MECHANISTIC STUDIES, K TAMAO,T HAYASHI,Y ITO, FRONTIERS OF ORGANOSILICON CHEMISTRY, ROYAL SOC CHEMISTRY, p. 197-207, 1991
  • Novel Pentacoordinate Anionic Silicate, [o-C<inf>6</inf>H<inf>4</inf>(SiPhF<inf>2</inf>)<inf>2</inf>F]<sup>-</sup>,K<sup>+</sup>-18-Crown-6, Containing a Bent Fluoride Bridge between Two Silicon Atoms, Tamao, K.,Hayashi, T.,Ito, Y.,Shiro, M., Journal of the American Chemical Society, Vol. 112, No. 6, 1990
  • Additions and Corrections: Novel Pentacoordinate Anionic Silicate, [o-C<inf>6</inf>H<inf>4</inf>(SiPhF<inf>2</inf>)<inf>2</inf>F]<sup>-</sup>, K<sup>+</sup>.18-Crown-6, Containing a Bent Fluoride Bridge between Two Silicon Atoms (Journal of the American Chemical Society (1990) 112 (2422-2424)), Tamao, K.,Hayashi, T.,Ito, Y.,Shiro, M., Journal of the American Chemical Society, AMER CHEMICAL SOC, Vol. 112, No. 14, p. 5679-5679, 1990
  • Structure and Reactivity of Hypercoordinate Silicon Compounds—Mechanism of Hydrogen Peroxide Oxidation of Silicon-Carbon Bonds—, Tamao, K.,Hayashi, T.,Ito, Y., Nippon Kagaku Kaishi, CHEMICAL SOC JAPAN, Vol. 1990, No. 5, p. 509-515, 1990
  • Ortho lithiation directed by amino groups on silicon in phenylsilane derivatives, Tamao, K.,Yao, H.,Tsutsumi, Y.,Abe, H.,Hayashi, T.,Ito, Y., Tetrahedron Letters, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 31, No. 20, p. 2925-2928, 1990
  • An efficient oxidative cleavage of carbon-silicon bonds by a dioxygen/hydroquinone system, Tamao, K.,Hayashi, T.,Ito, Y., Tetrahedron Letters, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 30, No. 47, p. 6533-6536, 1989
  • Electroreductive Intermolecular Coupling of Ketones with Olefins, Shono, T.,Kashimura, S.,Mori, Y.,Hayashi, T.,Soeiima, T.,Yamaguchi, Y., Journal of Organic Chemistry, AMER CHEMICAL SOC, Vol. 54, No. 26, p. 6001-6003, 1989
  • Oxidative cleavage of carbon-silicon bonds by dioxygen: Catalysis by a flavin-dihydronicotinamide redox system, Tamao, K.,Hayashi, T.,Ito, Y., Journal of the Chemical Society, Chemical Communications, ROYAL SOC CHEMISTRY, No. 12, p. 795-797, 1988
  • 1H NMR Characterization of the System Cobalt(II)bis(histamino)-β-Cyclodextrin-Imidazole, Takashi Hayashi, Gazz. Chim. Ital., SOC CHIMICA ITALIANA, Vol. 118, No. 11, p. 777-781, 1988

Misc.

  • Focusing on a nickel hydrocorphinoid in a protein matrix: methane generation by methyl-coenzyme M reductase with F430 cofactor and its models, Yuta Miyazaki,Koji Oohora,Takashi Hayashi, Chemical Society reviews, Vol. 51, No. 5, p. 1629-1639, 2022/03/07
  • CHAPTER 3: Myoglobin Derivatives Reconstituted with Modified Metal Porphyrinoids as Structural and Functional Models of the Cytochrome P450 Enzymes, Hayashi, T.,Oohora, K., RSC Metallobiology, Vol. 2019-January, No. 13, p. 63-78, 2019
  • Construction of a Hemoprotein Supramolecular 671 Polymer, Hayashi, T., Kobunshi, Vol. 66, No. 12, p. 671-672, 2017
  • Reconstitution of Heme Enzymes with Artificial Metalloporphyrinoids, Oohora, K.,Hayashi, T., Methods in Enzymology, ELSEVIER ACADEMIC PRESS INC, Vol. 580, p. 439-454, 2016
  • ヘムを介して配向担持されたセロビオースデヒドロゲナーゼ修飾バイオ電極の構築, 原田裕史,小野田晃,砂川直輝,五十嵐圭日子,林高史, 錯体化学会討論会講演要旨集, Vol. 65th, 2015
  • Artificial Metalloenzymes Containing an Organometallic Active Site, Onoda, A.,Hayashi, T.,Salmain, M., Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging, Wiley Blackwell, Vol. 9783527335275, p. 305-338, 2015
  • A Rhodium Complex-Linked beta Barrel Protein as a Hybrid Biocatalyst for Phenylacetylene Polymerization, A. Onoda,K. Fukumoto,T. Hayashi, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, SPRINGER, Vol. 19, p. S569-S569, 2014/03
  • Construction of a Methionine Synthase Model by Apomyoglobin Cobalt Corrin Complex, T. Hayashi,Y. Morita,K. Oohora, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, SPRINGER, Vol. 19, p. S92-S92, 2014/03
  • Incorporation of modified and artificial cofactors into naturally occurring protein scaffolds, Oohora, K.,Hayashi, T., Methods in Molecular Biology, Methods in Molecular Biology, Vol. 1216, p. 251-263, 2014
  • Listeria monocytogenesのヘム取込み系におけるヘム結合タンパク質HupDの性質, 岡本泰典,岡本泰典,林高史,澤井仁美,青野重利, 日本化学会講演予稿集, Vol. 93rd, No. 3, 2013
  • Generation of Functionalized Biomolecules using Hemoprotein Matrices with Small Protein Cavities for Incorporation of Cofactors, Hayashi, T., Coordination Chemistry in Protein Cages: Principles, Design, and Applications, John Wiley and Sons, p. 87-110, 2013
  • Construction of hemoprotein-based self-assembly systems, Vol. 63, No. 6, p. 458-462, 2012/06
  • Hemoproteins Reconstituted with Artificially Created Hemes, Takashi Hayashi, Handbook of Porphyrin Science, Vol. 5, p. 1-69, 2010
  • Handbook of Porphyrin Science, Vol.5, World Scientific, Vol. 1-69, 2010
  • Exo-Selective formation of bicyclic oxetanes in the Paterno-Buchi reaction of vinylene carbonate: the important role of intermediary triplet diradicals in the stereoselectivity, Manabu Abe,Kana Taniguchi,Takashi Hayashi, Archive for Organic Chemistry (ARKIVOC), Vol. Vol. 2007. No. viii, 58-65, p. 58-65, 2007
  • Enhancement of enzymatic activity for myoglobins by modification of heme-propionate side chains, Hayashi, T.,Sato, H.,Matsuo, T.,Matsuda, T.,Hitomi, Y.,Hisaeda, Y., Journal of Porphyrins and Phthalocyanines, SOC PORPHYRINS & PHTHALOCYANINES, Vol. 8, No. 1-3, p. 255-264, 2004
  • Enhancement of Enzymatic Activity for Myoglobins by Modification of Heme-Proponate Side Chains, Journal of Porphyrins and Phthalocyanines, Vol. Vol.8, No.6, 255-264, 2004
  • Role of heme-propionate side chains in myoglobin function, T Hayashi,T Matsuo,K Harada,Y Hisaeda,S Hirota,N Funasaki, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 96, No. 1, p. 50-50, 2003/07
  • Role of heme-propionate side chains in myoglobin function, T Hayashi,T Matsuo,K Harada,Y Hisaeda,S Hirota,N Funasaki, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 96, No. 1, p. 50-50, 2003/07
  • Chemical properties of reconstituted myoglobins with functionalized hemin derivatives, T Hayashi,T Ando,T Matsuda,H Sato,T Matsuo,Y Hisaeda, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 86, No. 1, p. 57-57, 2001/08
  • Photoinduced electron transfer within an artificially created protein-protein complex, T Ando,T Hayashi,H Sato,Y Hisaeda, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 86, No. 1, p. 124-124, 2001/08
  • New myoglobin reconstituted with an iron porphycene as a structural isomer of heme moiety, H Dejima,T Hayashi,T Matsuo,Y Hisaeda, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 86, No. 1, p. 200-200, 2001/08
  • Chemical properties of reconstituted myoglobins with functionalized hemin derivatives, T Hayashi,T Ando,T Matsuda,H Sato,T Matsuo,Y Hisaeda, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 86, No. 1, p. 57-57, 2001/08
  • Photoinduced electron transfer within an artificially created protein-protein complex, T Ando,T Hayashi,H Sato,Y Hisaeda, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 86, No. 1, p. 124-124, 2001/08
  • New myoglobin reconstituted with an iron porphycene as a structural isomer of heme moiety, H Dejima,T Hayashi,T Matsuo,Y Hisaeda, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 86, No. 1, p. 200-200, 2001/08
  • Molecular Modeling of Biological Electron Transfer via Molecular Recognition -Synthetic Receptor for Ubiquinone and Cytochrome c-, Hayashi, T., Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, Society of Synthetic Organic Chemistry, Vol. 56, No. 9, p. 745-754, 1998
  • Complexation between Reconstituted Myoglobin and Cytochrome c, J. Inorg. Biochem., Vol. 67, 1997
  • 合成ヘム再構成ミオグロビンを用いる光駆動電子移動反応, 有機合成化学研究所, Vol. 10, p. 83-90, 1996
  • Photoinduced Electron Transfer from Reconstitutd Myoglobin with Zinc Porphyrin to Viologen via Electrostatic Interaction, Annual Report of Researcb Institute for Orgauic Synthetic Chemistry, Vol. 10, p. 83-90, 1996
  • 動的分子認識過程解明のアプローチ, 有機合成化学研究所講演集, Vol. 9, p. 95-104, 1995
  • Approach to the Process of Dynamic Molecular Recognition, Annual Report of Research Institute for Organic Synthetic Chemistry, Vol. 9, p. 95-104, 1995
  • INTERMOLECULAR INTERACTION SYSTEM BETWEEN PORPHYRIN AND QUINONES - INDUCED FITTING MOLECULAR RECOGNITION AND ITS ELECTRON-TRANSFER, T HAYASHI,T MIYAHARA,M KOBAYASHI,H HOKAZONO,H OGOSHI, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, Vol. 203, p. 235-INOR, 1992/04
  • SPECIFIC MOLECULAR RECOGNITION VIA MULTIPOINT HYDROGEN-BONDING - PORPHYRIN-COENZYME Q ANALOGS PAIRING, HB OGOSHI,T HAYASHI,T MIYAHARA, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, Vol. 203, p. 228-INOR, 1992/04
  • 分子認識過程により制御された生体系電子移動のモデル化, 有機合成化学研究所, Vol. 6, p. 94-100, 1992
  • Artificial Model of Electron Transfer in Biological System controlled by Molecular Recognition Process, Annual Report of Research Institute for Organic Synthetic Chemistry, Vol. 6, p. 94-100, 1992

Publications

  • RSC Metallobiology, Takashi Hayashi,Koji Oohora, RSC, 2019/01
  • Peroxidase and Peroxygenase Activities of a Myoglobin Reconstituted with an Iron Porphycene, Biomolecular Chemistry, A Bridge for the Future, Proceeding of the ISBC2003,, 2003
  • Porphyrins and Metalloporphyrins as Receptor Models in Molecular Recognition, The Porphyrin Handbook, 2000
  • Porphyrins and Metalloporphyrins as Receptor Models in Molecular Recognition, The Porphyrin Handbook (Academic Press), 2000
  • Hydrogen Peroxide Oxidation of the Silicon-Carbon Bond : Mechanistic Studies, Frontiers of Organosilicon Chemistry, 1991
  • Hydrogen Peroxide Oxidation of the Silicon-Carbon Bond : Mechanistic Studies, Frontiers of Organosilicon Chemistry, 1991

Industrial Property Rights

  • Preparation of 2-Deoxy-2-fluoro-glycoside-bound Nucleotides as Glycosyltransferase Inhibitors

Works

  • ポルフィセン金属錯体を用いた新規触媒開発, 1999 - 2001
  • Development of New Catalyst by Metalloporphycene, 1999 - 2001
  • 修飾ヘムタンパク質の機能化, 2000 -
  • 蛋白質フラスコを用いた高効率酵素型触媒, 2000 -
  • New Functionalization of Modified Hemoproteins, 2000 -
  • A Highly Effective Catalyst by Hemoprotein Matrix, 2000 -
  • Preparation of 2-deoxy-2-fluoro-glycoside-bound nucleotides as glycosyltransferase inhibitors, 1998 -

Awards

  • Humboldt Research Award, Alexander von Humboldt Foundation, 2022/10
  • 第27回日本化学会学術賞, 日本化学会, 2010
  • BCSJ Article Awards, 2008
  • 第7回酵素応用シンポジウム研究奨励賞, 2006
  • 2001 九州大学総長賞, 2001
  • 2001 Kyushu University President Award, 2001
  • JPP 1st Young Investigator Award in Porphyrin Chemistry, 2000
  • 有機合成化学奨励賞, 2000
  • 平成11年度有機合成化学奨励賞, 2000
  • JPP 1st Young Investigator Award in Porphyrin Chemistry, 2000
  • 第9回井上研究奨励賞, 1992
  • 有機合成化学協会 鐘淵化学工業研究企画賞, 1991

Committee Memberships

  • 近畿化学協会, 理事, 2019/05 - Present
  • 日本化学会, 理事, 2019/05 - 2021/05
  • 錯体化学会, 副会長・理事, 2018/08 - 2020/09