顔写真

PHOTO

Hayashi Takashi
林 高史
Hayashi Takashi
林 高史
Graduate School of Engineering Division of Applied Chemistry, Professor

Research History 6

  1. 2005/04 - Present
    Faculty of Engineering, Osaka University Department of Applied Chemistry professor

  2. 2005/04 - 2007/03
    Institute for Molecular Science Visiting Professor

  3. 1997 - 2005
    Kyushu University

  4. 2000 - 2003
    科学技術振興事業団 さきがけ21「変換と制御」研究員

  5. 1990 - 1997
    京都大学 助手

  6. 1995 - 1996
    スクリプス研究所(アメリカ、カリフォルニア州) 客員研究員

Education 2

  1. Kyoto University Graduate School of Engineering

    1985/04 - 1990/03

  2. Kyoto University Faculty of Engineering

    1981/04 - 1985/03

Committee Memberships 5

  1. 日本学術振興会学術システム研究センター プログラムオフィサー(専門研究員) Government

    2022/04 - Present

  2. 近畿化学協会 理事 Academic society

    2019/05 - Present

  3. 日本化学会近畿支部 支部長 Academic society

    2023/03 - 2024/02

  4. 日本化学会 理事

    2019/05 - 2021/05

  5. 錯体化学会 副会長・理事

    2018/08 - 2020/09

Professional Memberships 9

  1. 錯体化学会

  2. 高分子学会

  3. 近畿化学協会

  4. 有機合成化学協会

  5. アメリカ化学会 (American Chemical Society)

  6. 日本化学会

  7. Society of Porphyrins and Phthalocyanines (SPP)

  8. Society of Biological Inorganic Chemistry (SBIC)

  9. American Chemical Society (Inorg. Div. and Organic Div.)

Research Areas 6

  1. Nanotechnology/Materials / Structural/physical organic chemistry / Supramolecular Chemistry

  2. Life sciences / Bioorganic chemistry / Protein Engineering

  3. Nanotechnology/Materials / Biochemistry /

  4. Nanotechnology/Materials / Synthetic organic chemistry /

  5. Nanotechnology/Materials / Inorganic and coordination chemistry / Bioinorganic Chemistry

  6. Nanotechnology/Materials / Molecular biochemistry /

Awards 12

  1. Humboldt Research Award

    Alexander von Humboldt Foundation 2022/10

  2. 第27回日本化学会学術賞

    日本化学会 2010

  3. BCSJ Article Awards

    2008

  4. 第7回酵素応用シンポジウム研究奨励賞

    2006

  5. 2001 九州大学総長賞

    2001

  6. 2001 Kyushu University President Award

    2001

  7. JPP 1st Young Investigator Award in Porphyrin Chemistry

    2000

  8. 有機合成化学奨励賞

    2000

  9. 平成11年度有機合成化学奨励賞

    2000

  10. JPP 1st Young Investigator Award in Porphyrin Chemistry

    2000

  11. 第9回井上研究奨励賞

    1992

  12. 有機合成化学協会 鐘淵化学工業研究企画賞

    1991

Papers 232

  1. Photo-induced imine reduction by a photoredox biocatalyst consisting of a pentapeptide and a Ru bipyridine terpyridine complex

    Ryusei Kano, Koji Oohora, Takashi Hayashi

    Journal of Inorganic Biochemistry Vol. 259 2024/10 Research paper (scientific journal)

  2. Reconstitution of Myoglobin with Iron Porphycene Generates an Artificial Aldoxime Dehydratase with Expanded Catalytic Activities

    Shunsuke Kato, Miteki Abe, Harald Gröger, Takashi Hayashi

    ACS Catalysis p. 13081-13087 2024/08/16 Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)
  3. Intramolecular C-H bond amination catalyzed by myoglobin reconstituted with iron porphycene

    Yoshiyuki Kagawa, Koji Oohora, Takashi Hayashi

    Journal of Inorganic Biochemistry Vol. 252 2024/03 Research paper (scientific journal)

  4. Elasticity tuning of a hexameric hemoprotein-based hydrogel by mutation of its protein building block

    Koji Oohora, Kazuki Kageyama, Yuri Hidaka, Takashi Hayashi

    Chemistry Letters Vol. 53 No. 2 2024/02 Research paper (scientific journal)

  5. Mechanochemical responses in β-lactoglobulin-based hydrogels: protein unfolding and chemical modification through compression

    Koji Oohora, Kazuki Kageyama, Hiroki Innami, Takashi Hayashi

    Chemistry Letters Vol. 53 No. 2 2024/02 Research paper (scientific journal)

  6. Redox Engineering of Myoglobin by Cofactor Substitution to Enhance Cyclopropanation Reactivity

    Yoshiyuki Kagawa, Koji Oohora, Tomoki Himiyama, Akihiro Suzuki, Takashi Hayashi

    Angewandte Chemie - International Edition 2024 Research paper (scientific journal)

  7. Rational design of an artificial ethylbenzene hydroxylase using a molecular dynamics simulation to enhance enantioselectivity

    Koji Oohora, Yoshiyuki Kagawa, Takako Nishiura, Eiichi Mizohata, Ulrich Schwaneberg, Takashi Hayashi

    Chemistry Letters Vol. 53 No. 2 2023/12/19 Research paper (scientific journal)

    Publisher: Oxford University Press (OUP)
  8. A polyacrylamide gel containing an engineered hexameric hemoprotein as a cross-linking unit toward redox-responsive materials

    Kazuki Kageyama, Koji Oohora, Takashi Hayashi

    RSC Advances Vol. 13 No. 49 p. 34610-34617 2023/11/27 Research paper (scientific journal)

  9. Chitin‐ and Streptavidin‐Mediated Affinity Purification Systems: A Screening Platform for Enzyme Discovery

    Shunsuke Kato, Koki Takeuchi, Motonao Iwaki, Kentaro Miyazaki, Kohsuke Honda, Takashi Hayashi

    Angewandte Chemie International Edition 2023/06/06 Research paper (scientific journal)

    Publisher: Wiley
  10. Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold

    Shunsuke Kato, Akira Onoda, Ulrich Schwaneberg, Takashi Hayashi

    Journal of the American Chemical Society 2023/03/09 Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)
  11. Disulfide Bond-mediated Oligomerization of a Green Fluorescent Protein in Solution

    Julian Wong Soon, Koji Oohora, Takayuki Uchihashi, Takashi Hayashi

    Chemistry Letters Vol. 52 No. 2 p. 105-109 2023/02 Research paper (scientific journal)

  12. Ethylbenzene oxidation by a hybrid catalysis system of reconstituted myoglobin and silica-protected PdAu nanoparticles under a hydrogen-oxygen mixed atmosphere

    Koji Oohora, Yoshiyuki Kagawa, Yasutaka Kuwahara, Hiromi Yamashita, Takashi Hayashi

    Journal of Porphyrins and Phthalocyanines 2023 Research paper (scientific journal)

  13. A disulphide bond-mediated hetero-dimer of a hemoprotein and a fluorescent protein exhibiting efficient energy transfer

    Julian Wong Soon, Koji Oohora, Takashi Hayashi

    RSC Advances Vol. 12 No. 44 p. 28519-28524 2022/10/06 Research paper (scientific journal)

  14. Reactivity of Myoglobin Reconstituted with Cobalt Corrole toward Hydrogen Peroxide

    Koji Oohora, Hirotaka Tomoda, Takashi Hayashi

    International Journal of Molecular Sciences Vol. 23 No. 9 2022/05/01 Research paper (scientific journal)

  15. DNA-Mediated Protein Shuttling between Coacervate-Based Artificial Cells

    Tsuyoshi Mashima, Marleen H.M.E. van Stevendaal, Femke R.A. Cornelissens, Alexander F. Mason, Bas J.H.M. Rosier, Wiggert J. Altenburg, Koji Oohora, Shota Hirayama, Takashi Hayashi, Jan C.M. van Hest, Luc Brunsveld

    Angewandte Chemie - International Edition Vol. 61 No. 17 2022/04 Research paper (scientific journal)

  16. Focusing on a nickel hydrocorphinoid in a protein matrix: methane generation by methyl-coenzyme M reductase with F430 cofactor and its models

    Yuta Miyazaki, Koji Oohora, Takashi Hayashi

    Chemical Society reviews Vol. 51 No. 5 p. 1629-1639 2022/03/07

  17. One‐Step Preparation of Fe/N/C Single‐Atom Catalysts Containing Fe−N 4 Sites from an Iron Complex Precursor with 5,6,7,8‐Tetraphenyl‐1,12‐Diazatriphenylene Ligands

    Koki Matsumoto, Masaru Kato, Ichizo Yagi, Siqi Xie, Kiyotaka Asakura, Shin‐ichiro Noro, Norimitsu Tohnai, Stéphane Campidelli, Takashi Hayashi, Akira Onoda

    Chemistry – A European Journal Vol. 28 No. 5 2022/01/24 Research paper (scientific journal)

    Publisher: Wiley
  18. Dynamic Protease Activation on a Multimeric Synthetic Protein Scaffold via Adaptable DNA‐Based Recruitment Domains

    Tsuyoshi Mashima, Bas J. H. M. Rosier, Koji Oohora, Tom F. A. Greef, Takashi Hayashi, Luc Brunsveld

    Angewandte Chemie International Edition Vol. 60 No. 20 p. 11262-11266 2021/05/10 Research paper (scientific journal)

    Publisher: Wiley
  19. Thermally Controlled Construction of Fe-N <inf>x</inf>Active Sites on the Edge of a Graphene Nanoribbon for an Electrocatalytic Oxygen Reduction Reaction

    Koki Matsumoto, Akira Onoda, Tomoyuki Kitano, Takao Sakata, Hidehiro Yasuda, Stéphane Campidelli, Takashi Hayashi

    ACS Applied Materials and Interfaces Vol. 13 No. 13 p. 15101-15112 2021/04 Research paper (scientific journal)

  20. Construction of a whole-cell biohybrid catalyst using a Cp*Rh(III)-dithiophosphate complex as a precursor of a metal cofactor

    Shunsuke Kato, Akira Onoda, Alexander R. Grimm, Ulrich Schwaneberg, Takashi Hayashi

    Journal of Inorganic Biochemistry Vol. 216 2021/03 Research paper (scientific journal)

  21. Directed Evolution of a Cp*RhIII-Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification

    Shunsuke Kato, Akira Onoda, Naomasa Taniguchi, Ulrich Schwaneberg, Takashi Hayashi

    ChemBioChem Vol. 22 No. 4 p. 679-685 2021/02/15 Research paper (scientific journal)

  22. Myoglobins engineered with artificial cofactors serve as artificial metalloenzymes and models of natural enzymes

    Koji Oohora, Takashi Hayashi

    Dalton Transactions Vol. 50 No. 6 p. 1940-1949 2021/02/14

  23. A supramolecular assembly of hemoproteins formed in a star-shaped structure via heme–heme pocket interactions

    Julian Wong Soon, Koji Oohora, Shota Hirayama, Takashi Hayashi

    International Journal of Molecular Sciences Vol. 22 No. 3 p. 1-13 2021/02/01 Research paper (scientific journal)

  24. Functional Myoglobin Model Composed of a Strapped Porphyrin/Cyclodextrin Supramolecular Complex with an Overhanging COOH That Increases O<inf>2</inf>/CO Binding Selectivity in Aqueous Solution

    Qiyue Mao, Pradip K. Das, Stéphane Le Gac, Bernard Boitrel, Vincent Dorcet, Koji Oohora, Takashi Hayashi, Hiroaki Kitagishi

    Inorganic Chemistry Vol. 60 No. 16 p. 12392-12404 2021 Research paper (scientific journal)

  25. Effect of Molecule-Substrate Interactions on the Adsorption of meso-Dibenzoporphycene Tautomers Studied by Scanning Probe Microscopy and First-Principles Calculations

    Tomoko K. Shimizu, Carlos Romero-Muñiz, Oleksandr Stetsovych, Jaime Carracedo-Cosme, Michael Ellner, Pablo Pou, Koji Oohora, Takashi Hayashi, Ruben Perez, Oscar Custance

    Journal of Physical Chemistry C Vol. 124 No. 49 p. 26759-26768 2020/12/10 Research paper (scientific journal)

  26. Incorporation of a Cp*Rh(III)-dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp2)-H Bond Functionalization

    Shunsuke Kato, Akira Onoda, Alexander R. Grimm, Kengo Tachikawa, Ulrich Schwaneberg, Takashi Hayashi

    Inorganic Chemistry Vol. 59 No. 19 p. 14457-14463 2020/10/05 Research paper (scientific journal)

  27. Chiral paddle-wheel diruthenium complexes for asymmetric catalysis

    Taku Miyazawa, Takuro Suzuki, Yuhei Kumagai, Koji Takizawa, Takashi Kikuchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi, Yuji Kamei, Futa Kamiyama, Masahiro Anada, Masahiro Kojima, Tatsuhiko Yoshino, Shigeki Matsunaga

    Nature Catalysis Vol. 3 No. 10 p. 851-858 2020/10/01 Research paper (scientific journal)

  28. Methane generation and reductive debromination of benzylic position by reconstituted myoglobin containing nickel tetradehydrocorrin as a model of methyl-coenzyme M reductase

    Yuta Miyazaki, Koji Oohora, Takashi Hayashi

    Inorganic Chemistry Vol. 59 No. 17 p. 11995-12004 2020/09/08 Research paper (scientific journal)

  29. Triazolecarbaldehyde Reagents for One-Step N-Terminal Protein Modification

    Akira Onoda, Nozomu Inoue, Eigo Sumiyoshi, Takashi Hayashi

    ChemBioChem Vol. 21 No. 9 p. 1274-1278 2020/05/04 Research paper (scientific journal)

  30. Construction of a hexameric hemoprotein sheet and direct observation of dynamic processes of its formation

    Oohora, K., Hirayama, S., Uchihashi, T., Hayashi, T.

    Chemistry Letters Vol. 49 No. 2 2020 Research paper (scientific journal)

  31. Thermoresponsive Micellar Assembly Constructed from a Hexameric Hemoprotein Modified with Poly(N-isopropylacrylamide) toward an Artificial Light-Harvesting System

    Hirayama, S., Oohora, K., Uchihashi, T., Hayashi, T.

    Journal of the American Chemical Society Vol. 142 No. 4 p. 1822-1831 2020 Research paper (scientific journal)

  32. Supramolecular dimerization of a hexameric hemoprotein via multiple pyrene-pyrene interactions

    Oohora, K., Hirayama, S., Mashima, T., Hayashi, T.

    Journal of Porphyrins and Phthalocyanines Vol. 24 No. 1-3 p. 259-267 2020 Research paper (scientific journal)

    Publisher: World Scientific Pub Co Pte Lt
  33. A ring-shaped hemoprotein trimer thermodynamically controlled by the supramolecular heme-heme pocket interaction

    Oohora, K., Kajihara, R., Fujimaki, N., Uchihashi, T., Hayashi, T.

    Chemical Communications Vol. 55 No. 11 p. 1544-1547 2019 Research paper (scientific journal)

  34. Electrochemical CO<inf>2</inf> reduction by a cobalt bipyricorrole complex: Decrease of an overpotential value derived from monoanionic ligand character of the porphyrinoid species

    Ogawa, A., Oohora, K., Gu, W., Hayashi, T.

    Chemical Communications Vol. 55 No. 4 p. 493-496 2019 Research paper (scientific journal)

  35. Photoinduced electron transfer within supramolecular hemoprotein co-assemblies and heterodimers containing Fe and Zn porphyrins

    Kajihara, R., Oohora, K., Hayashi, T.

    Journal of Inorganic Biochemistry Vol. 193 p. 42-51 2019 Research paper (scientific journal)

  36. Arginine residues provide a multivalent effect for cellular uptake of a hemoprotein assembly

    Oohora, K., Kajihara, R., Jiromaru, M., Kitagishi, H., Hayashi, T.

    Chemistry Letters Vol. 48 No. 3 p. 295-298 2019 Research paper (scientific journal)

  37. Hemoproteins Reconstituted with Artificial Metal Complexes as Biohybrid Catalysts

    Oohora, K., Onoda, A., Hayashi, T.

    Accounts of Chemical Research Vol. 52 No. 4 p. 945-954 2019 Research paper (scientific journal)

  38. Light triggers molecular shuttling in rotaxanes: Control over proximity and charge recombination

    Wolf, M., Ogawa, A., Bechtold, M., Vonesch, M., Wytko, J.A., Oohora, K., Campidelli, S., Hayashi, T., Guldi, D.M., Weiss, J.

    Chemical Science Vol. 10 No. 13 p. 3846-3853 2019 Research paper (scientific journal)

  39. Myoglobin Reconstituted with Ni Tetradehydrocorrin as a Methane-Generating Model of Methyl-coenzyme M Reductase

    Oohora, K., Miyazaki, Y., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 58 No. 39 p. 13813-13817 2019 Research paper (scientific journal)

  40. Site-Specific Modification of Proteins through N-Terminal Azide Labeling and a Chelation-Assisted CuAAC Reaction

    Inoue, N., Onoda, A., Hayashi, T.

    Bioconjugate Chemistry Vol. 30 No. 9 p. 2427-2434 2019 Research paper (scientific journal)

  41. Methane generation via intraprotein C–S bond cleavage in cytochrome b<inf>562</inf> reconstituted with nickel didehydrocorrin

    Miyazaki, Y., Oohora, K., Hayashi, T.

    Journal of Organometallic Chemistry Vol. 901 2019 Research paper (scientific journal)

  42. Photochemical dyads and triads built on rotaxane architectures

    Ogawa Ayumu, Bechtold Mareike, Wolf Maximilian, Wytko Jennifer, Oohora Koji, Hayashi Takashi, Guldi Dirk, Campidelli Stephane, Weiss Jean

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 255 2018/03/18

  43. Artificially Created Metalloenzyme Consisting of an Organometallic Complex Immobilized to a Protein Matrix

    Sauer, D.F., Matsuo, T., Onoda, A., Okuda, J., Hayashi, T.

    Advances in Bioorganometallic Chemistry p. 307-328 2018 Research paper (scientific journal)

  44. Nonprecious-metal Fe/N/C Catalysts Prepared from π-Expanded Fe Salen Precursors toward an Efficient Oxygen Reduction Reaction

    Tanaka, Y., Onoda, A., Okuoka, S.-I., Kitano, T., Matsumoto, K., Sakata, T., Yasuda, H., Hayashi, T.

    ChemCatChem Vol. 10 No. 4 p. 653-653 2018 Research paper (scientific journal)

  45. Roles of N- and C-terminal domains in the ligand-binding properties of cytoglobin

    Hanai, S., Tsujino, H., Yamashita, T., Torii, R., Sawai, H., Shiro, Y., Oohora, K., Hayashi, T., Uno, T.

    Journal of Inorganic Biochemistry Vol. 179 p. 1-9 2018 Research paper (scientific journal)

  46. Mitochondria-Targeting Polyamine–Protoporphyrin Conjugates for Photodynamic Therapy

    Taba, F., Onoda, A., Hasegawa, U., Enoki, T., Ooyama, Y., Ohshita, J., Hayashi, T.

    ChemMedChem Vol. 13 No. 1 p. 15-19 2018 Research paper (scientific journal)

  47. Bimetallic M/N/C catalysts prepared from π-expanded metal salen precursors toward an efficient oxygen reduction reaction

    Onoda, A., Tanaka, Y., Matsumoto, K., Ito, M., Sakata, T., Yasuda, H., Hayashi, T.

    RSC Advances Vol. 8 No. 6 p. 2892-2899 2018 Research paper (scientific journal)

  48. Successive energy transfer within multiple photosensitizers assembled in a hexameric hemoprotein scaffold

    Mashima, T., Oohora, K., Hayashi, T.

    Physical Chemistry Chemical Physics Vol. 20 No. 5 p. 3200-3209 2018 Research paper (scientific journal)

  49. Preparation and characterization of myoglobin reconstituted with Fe(II) oxaporphyrin: The monoanionic macrocycle provides unique cyanide binding behavior for the ferrous species

    Meichin, H., Oohora, K., Hayashi, T.

    Inorganica Chimica Acta Vol. 472 p. 184-191 2018 Research paper (scientific journal)

  50. A water-soluble supramolecular complex that mimics the heme/copper hetero-binuclear site of cytochrome: C oxidase

    Kitagishi, H., Shimoji, D., Ohta, T., Kamiya, R., Kudo, Y., Onoda, A., Hayashi, T., Weiss, J., Wytko, J.A., Kano, K.

    Chemical Science Vol. 9 No. 7 p. 1989-1995 2018 Research paper (scientific journal)

  51. A Whole Cell E. coli Display Platform for Artificial Metalloenzymes: Poly(phenylacetylene) Production with a Rhodium-Nitrobindin Metalloprotein

    Grimm, A.R., Sauer, D.F., Polen, T., Zhu, L., Hayashi, T., Okuda, J., Schwaneberg, U.

    ACS Catalysis Vol. 8 No. 3 p. 2611-2614 2018 Research paper (scientific journal)

  52. Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis

    Grimm, A.R., Sauer, D.F., Davari, M.D., Zhu, L., Bocola, M., Kato, S., Onoda, A., Hayashi, T., Okuda, J., Schwaneberg, U.

    ACS Catalysis Vol. 8 No. 4 p. 3358-3364 2018 Research paper (scientific journal)

  53. Supramolecular Hemoprotein Assembly with a Periodic Structure Showing Heme-Heme Exciton Coupling

    Oohora, K., Fujimaki, N., Kajihara, R., Watanabe, H., Uchihashi, T., Hayashi, T.

    Journal of the American Chemical Society Vol. 140 No. 32 p. 10145-10148 2018 Research paper (scientific journal)

  54. Synthesis and Characterization of meso-Substituted Cobalt Tetradehydrocorrin and Evaluation of Its Electrocatalytic Behavior Toward CO <inf>2</inf> Reduction and H <inf>2</inf> Evolution

    Ogawa, A., Oohora, K., Hayashi, T.

    Inorganic Chemistry Vol. 57 No. 23 p. 14644-14652 2018 Research paper (scientific journal)

  55. A Heterogeneous Hydrogen-Evolution Catalyst Based on a Mesoporous Organosilica with a Diiron Catalytic Center Modelling [FeFe]-Hydrogenase

    Himiyama, T., Waki, M., Esquivel, D., Onoda, A., Hayashi, T., Van Der Voort, P., Inagaki, S.

    ChemCatChem Vol. 10 No. 21 p. 4908-4913 2018 Research paper (scientific journal)

  56. Olefin metathesis catalysts embedded in β-barrel proteins: Creating artificial metalloproteins for olefin metathesis

    Sauer, D.F., Schiffels, J., Hayashi, T., Schwaneberg, U., Okuda, J.

    Beilstein Journal of Organic Chemistry Vol. 14 p. 2861-2871 2018 Research paper (scientific journal)

  57. Titelbild: A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction (Angew. Chem. 44/2017)

    Tomoki Himiyama, Naomasa Taniguchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi

    Angewandte Chemie Vol. 129 No. 44 2017/10

    Publisher: Wiley-Blackwell
  58. Cover Picture: A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction (Angew. Chem. Int. Ed. 44/2017)

    Tomoki Himiyama, Naomasa Taniguchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi

    Angewandte Chemie International Edition Vol. 56 No. 44 2017/10

    Publisher: Wiley-Blackwell
  59. Double active template strategy for functional rotaxane synthesis

    Weiss Jean, Wytko Jennifer, Hayashi Takashi, Miyazaki Yuta

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 253 2017/04/02

  60. Enhanced visible light response of a WO<inf>3</inf> photoelectrode with an immobilized fibrous gold nanoparticle assembly using an amyloid-β peptide

    Onoda, A., Harada, H., Uematsu, T., Kuwabata, S., Yamanaka, R., Sakurai, S., Hayashi, T.

    RSC Advances Vol. 7 No. 2 p. 1089-1092 2017 Research paper (scientific journal)

  61. Redox Potentials of Cobalt Corrinoids with Axial Ligands Correlate with Heterolytic Co-C Bond Dissociation Energies

    Morita, Y., Oohora, K., Sawada, A., Kamachi, T., Yoshizawa, K., Hayashi, T.

    Inorganic Chemistry Vol. 56 No. 4 p. 1950-1955 2017 Research paper (scientific journal)

  62. Cobalt tetradehydrocorrins coordinated by imidazolate-like histidine in the heme pocket of horseradish peroxidase

    Oohora, K., Tang, N., Morita, Y., Hayashi, T.

    Journal of Biological Inorganic Chemistry Vol. 22 No. 5 p. 695-703 2017 Research paper (scientific journal)

  63. A supramolecular assembly based on an engineered hemoprotein exhibiting a thermal stimulus-driven conversion to a new distinct supramolecular structure

    Koji Oohora, Yoshitaka Onuma, Yuta Tanaka, Akira Onoda, Takashi Hayashi

    Chemical Communications Vol. 53 No. 51 p. 6879-6882 2017 Research paper (scientific journal)

  64. Iron-Strapped Porphyrins with Carboxylic Acid Groups Hanging over the Coordination Site: Synthesis, X-ray Characterization, and Dioxygen Binding

    Boitrel, B., Hijazi, I., Roisnel, T., Oohora, K., Hayashi, T.

    Inorganic Chemistry Vol. 56 No. 13 p. 7373-7383 2017 Research paper (scientific journal)

  65. Interdomain flip-flop motion visualized in flavocytochrome cellobiose dehydrogenase using high-speed atomic force microscopy during catalysis

    Harada, H., Onoda, A., Uchihashi, T., Watanabe, H., Sunagawa, N., Samejima, M., Igarashi, K., Hayashi, T.

    Chemical Science Vol. 8 No. 9 p. 6561-6565 2017 Research paper (scientific journal)

  66. CuAAC in a Distal Pocket: Metal Active-Template Synthesis of Strapped-Porphyrin [2]Rotaxanes

    Miyazaki, Y., Kahlfuss, C., Ogawa, A., Matsumoto, T., Wytko, J.A., Oohora, K., Hayashi, T., Weiss, J.

    Chemistry - A European Journal Vol. 23 No. 55 p. 13579-13582 2017 Research paper (scientific journal)

  67. A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels–Alder Reaction

    Himiyama, T., Taniguchi, N., Kato, S., Onoda, A., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 56 No. 44 p. 13618-13622 2017 Research paper (scientific journal)

  68. Catalytic Cyclopropanation by Myoglobin Reconstituted with Iron Porphycene: Acceleration of Catalysis due to Rapid Formation of the Carbene Species

    Oohora, K., Meichin, H., Zhao, L., Wolf, M.W., Nakayama, A., Hasegawa, J.-Y., Lehnert, N., Hayashi, T.

    Journal of the American Chemical Society Vol. 139 No. 48 p. 17265-17268 2017 Research paper (scientific journal)

  69. Cofactor-specific anchoring of horseradish peroxidase onto a polythiophene-modified electrode

    Onoda, A., Umeda, Y., Hayashi, T.

    Chemistry Letters Vol. 46 No. 12 p. 1818-1821 2017 Research paper (scientific journal)

  70. meso-tetraaryl(porphyrinato)cobalt(III)-catalyzed oxygenation of disilanes under aerobic conditions

    Ohshita, J., Matsumura, Y., Nakayama, T., Yoshida, H., Kunai, A., Hisaeda, Y., Hayashi, T.

    Chemistry Letters Vol. 46 No. 12 p. 1807-1809 2017 Research paper (scientific journal)

  71. Manganese(V) Porphycene Complex Responsible for Inert C-H Bond Hydroxylation in a Myoglobin Matrix

    Oohora, K., Meichin, H., Kihira, Y., Sugimoto, H., Shiro, Y., Hayashi, T.

    Journal of the American Chemical Society Vol. 139 No. 51 p. 18460-18463 2017 Research paper (scientific journal)

  72. Substitution of an amino acid residue axially coordinating to the heme molecule in hexameric tyrosine-coordinated hemoprotein to enhance peroxidase activity

    Mashima, T., Oohora, K., Hayashi, T.

    Journal of Porphyrins and Phthalocyanines Vol. 21 No. 12 p. 824-831 2017 Research paper (scientific journal)

  73. 5B35: Serial Femtosecond Crystallography (SFX) of Ground State Bacteriorhodopsin Crystallized from Bicelles Determined Using 7-keV X-ray Free Electron Laser (XFEL) at SACLA

    Nakane T, Hanashima S, Suzuki M, Saiki H, Hayashi T, Kakinouchi K, Sugiyama S, Kawatake S, Matsuoka S, Matsumori N, Nango E, Kobayashi J, Shimamura T, Kimura K, Mori C, Kunishima N, Sugahara M, Takakyu Y, Inoue S, Masuda T, Hosaka T, Tono K, Joti Y, Kameshima T, Hatsui T, Yabashi M, Inoue T, Nureki O, Iwata S, Murata M, Mizohata E

    Worldwide Protein Data Bank 2016

  74. Artificial Diels-Alderase based on the transmembrane protein FhuA

    Osseili, H., Sauer, D.F., Beckerle, K., Arlt, M., Himiyama, T., Polen, T., Onoda, A., Schwaneberg, U., Hayashi, T., Okuda, J.

    Beilstein Journal of Organic Chemistry Vol. 12 p. 1314-1321 2016 Research paper (scientific journal)

  75. Crystal Structures and Coordination Behavior of Aqua- and Cyano-Co(III) Tetradehydrocorrins in the Heme Pocket of Myoglobin

    Morita, Y., Oohora, K., Mizohata, E., Sawada, A., Kamachi, T., Yoshizawa, K., Inoue, T., Hayashi, T.

    Inorganic Chemistry Vol. 55 No. 3 p. 1287-1295 2016 Research paper (scientific journal)

  76. Intraprotein transmethylation via a CH<inf>3</inf>-Co(iii) species in myoglobin reconstituted with a cobalt corrinoid complex

    Morita, Y., Oohora, K., Sawada, A., Doitomi, K., Ohbayashi, J., Kamachi, T., Yoshizawa, K., Hisaeda, Y., Hayashi, T.

    Dalton Transactions Vol. 45 No. 8 p. 3277-3284 2016 Research paper (scientific journal)

  77. Oxygen-binding Protein Fiber and Microgel: Supramolecular Myoglobin-Poly(acrylate) Conjugates

    Ono, T., Hisaoka, Y., Onoda, A., Oohora, K., Hayashi, T.

    Chemistry - An Asian Journal Vol. 11 No. 7 p. 1036-1042 2016 Research paper (scientific journal)

  78. Construction of a hybrid biocatalyst containing a covalently-linked terpyridine metal complex within a cavity of aponitrobindin

    Himiyama, T., Sauer, D.F., Onoda, A., Spaniol, T.P., Okuda, J., Hayashi, T.

    Journal of Inorganic Biochemistry Vol. 158 p. 55-61 2016 Research paper (scientific journal)

  79. Photocatalytic Properties of TiO<inf>2</inf> Composites Immobilized with Gold Nanoparticle Assemblies Using the Streptavidin-Biotin Interaction

    Harada, H., Onoda, A., Uematsu, T., Kuwabata, S., Hayashi, T.

    Langmuir Vol. 32 No. 25 p. 6459-6467 2016 Research paper (scientific journal)

  80. Cofactor-specific covalent anchoring of cytochrome: B <inf>562</inf> on a single-walled carbon nanotube by click chemistry

    Onoda, A., Inoue, N., Campidelli, S., Hayashi, T.

    RSC Advances Vol. 6 No. 70 p. 65936-65940 2016 Research paper (scientific journal)

  81. Anchoring Cytochrome b<inf>562</inf>on a Gold Nanoparticle by a Heme–Heme Pocket Interaction

    Onoda, A., Taniguchi, T., Inoue, N., Kamii, A., Hayashi, T.

    European Journal of Inorganic Chemistry Vol. 2016 No. 21 p. 3454-3459 2016 Research paper (scientific journal)

  82. In Situ Observation of Enhanced Photoinduced Charge Separation in a Gold Nanoparticle Assembly Immobilized on TiO<inf>2</inf>

    Harada, H., Onoda, A., Moriguchi, S., Hayashi, T.

    ChemistrySelect Vol. 1 No. 18 p. 5666-5670 2016 Research paper (scientific journal)

  83. Biohybrid catalysts constructed in a protein matrix with an artificial metal complex

    Hayashi Takashi, Onoda Akira, Oohora Koji

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 250 2015/08/16

  84. Generation of new artificial metalloproteins by cofactor modification of native hemoproteins

    Hayashi, T., Sano, Y., Onoda, A.

    Israel Journal of Chemistry Vol. 55 No. 1 p. 76-84 2015 Research paper (scientific journal)

  85. Myoglobin-based non-precious metal carbon catalysts for an oxygen reduction reaction

    Onoda, A., Tanaka, Y., Ono, T., Takeuchi, S., Sakai, A., Hayashi, T.

    Journal of Porphyrins and Phthalocyanines Vol. 19 No. 1-3 p. 510-516 2015 Research paper (scientific journal)

  86. Artificial hydrogenase: Biomimetic approaches controlling active molecular catalysts

    Onoda, A., Hayashi, T.

    Current Opinion in Chemical Biology Vol. 25 p. 133-140 2015 Research paper (scientific journal)

  87. Meso-Dibenzoporphycene has a Large Bathochromic Shift and a Porphycene Framework with an Unusual cis Tautomeric Form

    Oohora, K., Ogawa, A., Fukuda, T., Onoda, A., Hasegawa, J.-Y., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 54 No. 21 p. 6227-6230 2015 Research paper (scientific journal)

  88. Energy migration within hexameric hemoprotein reconstituted with Zn porphyrinoid molecules

    Oohora, K., Mashima, T., Ohkubo, K., Fukuzumi, S., Hayashi, T.

    Chemical Communications Vol. 51 No. 55 p. 11138-11140 2015 Research paper (scientific journal)

  89. A Highly Active Biohybrid Catalyst for Olefin Metathesis in Water: Impact of a Hydrophobic Cavity in a β-Barrel Protein

    Sauer, D.F., Himiyama, T., Tachikawa, K., Fukumoto, K., Onoda, A., Mizohata, E., Inoue, T., Bocola, M., Schwaneberg, U., Hayashi, T., Okuda, J.

    ACS Catalysis Vol. 5 No. 12 p. 7519-7522 2015 Research paper (scientific journal)

  90. Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation

    Herzog Konrad, Bracco Paula, Onoda Akira, Hayashi Takashi, Hoffmann Kurt, Schallmey Anett

    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY Vol. 70 p. 2875-2889 2014/11

  91. Catalytic alkane hydroxylation by myoglobin containing a manganese porphycene complex

    Koji Oohora, Hiroyuki Meichin, Yushi Kihira, Takako Nishiura, Takashi Hayashi

    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY Vol. 19 p. S770-S771 2014/08

  92. Structure and function of heme-binding proteins in heme-uptake systems of gram-positive bacteria

    Norifumi Muraki, Yasunori Okamoto, Takashi Hayashi, Shigetoshi Aono

    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY Vol. 19 p. S846-S847 2014/08

  93. Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation

    Herzog, K., Bracco, P., Onoda, A., Hayashi, T., Hoffmann, K., Schallmey, A.

    Acta Crystallographica Section D: Biological Crystallography Vol. 70 No. 11 p. 2875-2889 2014 Research paper (scientific journal)

  94. H<inf>2</inf>O<inf>2</inf>-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin

    Okamoto, Y., Onoda, A., Sugimoto, H., Takano, Y., Hirota, S., Kurtz, D.M., Shiro, Y., Hayashi, T.

    Chemical Communications Vol. 50 No. 26 p. 3421-3423 2014 Research paper (scientific journal)

  95. Fabrication of enzyme-degradable and size-controlled protein nanowires using single particle nano-fabrication technique

    Omichi, M., Asano, A., Tsukuda, S., Takano, K., Sugimoto, M., Saeki, A., Sakamaki, D., Onoda, A., Hayashi, T., Seki, S.

    Nature Communications Vol. 5 2014 Research paper (scientific journal)

  96. Rhodium-complex-linked hybrid biocatalyst: Stereo-controlled phenylacetylene polymerization within an engineered protein cavity

    Fukumoto, K., Onoda, A., Mizohata, E., Bocola, M., Inoue, T., Schwaneberg, U., Hayashi, T.

    ChemCatChem Vol. 6 No. 5 p. 1229-1235 2014 Research paper (scientific journal)

  97. Hemoprotein-based supramolecular assembling systems

    Oohora, K., Hayashi, T.

    Current Opinion in Chemical Biology Vol. 19 No. 1 p. 154-161 2014 Research paper (scientific journal)

  98. Photochemical property of a myoglobin-CdTe quantum dot conjugate formed by supramolecular host-guest interactions

    Himiyama, T., Onoda, A., Hayashi, T.

    Chemistry Letters Vol. 43 No. 7 p. 1152-1154 2014 Research paper (scientific journal)

  99. Photoinduced hydrogen evolution catalyzed by a synthetic diiron dithiolate complex embedded within a protein matrix

    Onoda, A., Kihara, Y., Fukumoto, K., Sano, Y., Hayashi, T.

    ACS Catalysis Vol. 4 No. 8 p. 2645-2648 2014 Research paper (scientific journal)

  100. Co(II)/Co(I) reduction-induced axial histidine-flipping in myoglobin reconstituted with a cobalt tetradehydrocorrin as a methionine synthase model

    Hayashi, T., Morita, Y., Mizohata, E., Oohora, K., Ohbayashi, J., Inoue, T., Hisaeda, Y.

    Chemical Communications Vol. 50 No. 83 p. 12560-12563 2014 Research paper (scientific journal)

  101. Heme-binding properties of HupD functioning as a substrate-binding protein in a heme-uptake ABC-transporter system in Listeria monocytogenes

    Okamoto, Y., Sawai, H., Ogura, M., Uchida, T., Ishimori, K., Hayashi, T., Aono, S.

    Bulletin of the Chemical Society of Japan Vol. 87 No. 10 p. 1140-1146 2014 Research paper (scientific journal)

  102. SACLAを利用したXFEL微結晶構造解析

    溝端栄一, 鈴木守, 南後恵理子, 森田能次, 垣之内啓介, 田中里枝, 登野健介, 城地保昌, 亀島敬, Jaehyun Park, Changyong Song, 初井宇記, 矢橋牧名, Thomas A White, 北郷悠, 大洞光司, 石田英子, 廣瀬未果, 杉山成, 村田道雄, 林高史, 高木淳一, 井上豪, 岩田想

    2013/10 Research paper (other academic)

  103. Photoinduced electron transfer of ZnS-AgInS<inf>2</inf> solid-solution semiconductor nanoparticles: Emission quenching and photocatalytic reactions controlled by electrostatic forces

    Uematsu, T., Doko, A., Torimoto, T., Oohora, K., Hayashi, T., Kuwabata, S.

    Journal of Physical Chemistry C Vol. 117 No. 30 p. 15667-15676 2013 Research paper (scientific journal)

  104. Supramolecular Linear Assemblies of Cytochrome b<inf>562</inf> Immobilized on a Gold Electrode

    Kakikura, Y., Onoda, A., Kubo, E., Kitagishi, H., Uematsu, T., Kuwabata, S., Hayashi, T.

    Journal of Inorganic and Organometallic Polymers and Materials Vol. 23 No. 1 p. 172-179 2013 Research paper (scientific journal)

  105. Cathodic photocurrent generation from zinc-substituted cytochrome b <inf>562</inf> assemblies immobilized on an apocytochrome b<inf>562</inf>- modified gold electrode

    Onoda, A., Kakikura, Y., Hayashi, T.

    Dalton Transactions Vol. 42 No. 45 p. 16102-16107 2013 Research paper (scientific journal)

  106. Complimenting a metal complex with protein environment toward a new hybrid biocatalyst

    Onoda, A., Hayashi, T.

    Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry Vol. 71 No. 5 p. 452-460 2013 Research paper (scientific journal)

  107. Crystal structure, exogenous ligand binding, and redox properties of an engineered diiron active site in a bacterial hemerythrin

    Okamoto, Y., Onoda, A., Sugimoto, H., Takano, Y., Hirota, S., Kurtz, D.M., Shiro, Y., Hayashi, T.

    Inorganic Chemistry Vol. 52 No. 22 p. 13014-13020 2013 Research paper (scientific journal)

  108. C(sp3)-H bond hydroxylation catalyzed by myoglobin reconstituted with manganese porphycene

    Oohora, K., Kihira, Y., Mizohata, E., Inoue, T., Hayashi, T.

    Journal of the American Chemical Society Vol. 135 No. 46 p. 17282-17285 2013 Research paper (scientific journal)

  109. Erratum: An extremely long-lived singlet 4,4-dimethoxy-3,5- diphenylpyrazolidine-3,5-diyl derivative: A notable nitrogen-atom effect on intra- and intermolecular reactivity (Angewandte Chemie - International Edition (2006) 45 (7828-7831) DOI:10.1002/anie.200603287)

    Abe, M., Kubo, E., Nozaki, K., Matsuo, T., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 51 No. 48 p. 11924-11924 2012 Research paper (scientific journal)

  110. Creation of an artificial metalloprotein with a Hoveyda–Grubbs catalyst moiety through the intrinsic inhibition mechanism of α-chymotrypsin

    Matsuo, T., Imai, C., Yoshida, T., Saito, T., Hayashi, T., Hirota, S.

    Chemical Communications Vol. 48 No. 11 p. 1662-1664 2012 Research paper (scientific journal)

  111. Photocatalytic hydrogen evolution by a diiron hydrogenase model based on a peptide fragment of cytochrome c <inf>556</inf> with an attached diiron carbonyl cluster and an attached ruthenium photosensitizer

    Sano, Y., Onoda, A., Hayashi, T.

    Journal of Inorganic Biochemistry Vol. 108 p. 159-162 2012 Research paper (scientific journal)

  112. Photocurrent generation from hierarchical zinc-substituted hemoprotein assemblies immobilized on a gold electrode

    Onoda, A., Kakikura, Y., Uematsu, T., Kuwabata, S., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 51 No. 11 p. 2628-2631 2012 Research paper (scientific journal)

  113. Chemically programmed supramolecular assembly of hemoprotein and streptavidin with alternating alignment

    Oohora, K., Burazerovic, S., Onoda, A., Wilson, Y.M., Ward, T.R., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 51 No. 16 p. 3818-3821 2012 Research paper (scientific journal)

  114. Reaction of cobalt porphycene with hydride reagents: Spectroscopic detection of Co-H porphycene species and formation of Co-SnR<inf>3</inf> porphycene species

    Matsuo, T., Komatsuzaki, K., Tsuji, T., Hayashi, T.

    Journal of Porphyrins and Phthalocyanines Vol. 16 No. 5-6 p. 616-625 2012 Research paper (scientific journal)

  115. Photochemical properties of a myoglobin-CdTe quantum dot conjugate

    Onoda, A., Himiyama, T., Ohkubo, K., Fukuzumi, S., Hayashi, T.

    Chemical Communications Vol. 48 No. 65 p. 8054-8056 2012 Research paper (scientific journal)

  116. A rhodium complex-linked β-barrel protein as a hybrid biocatalyst for phenylacetylene polymerization

    Onoda, A., Fukumoto, K., Arlt, M., Bocola, M., Schwaneberg, U., Hayashi, T.

    Chemical Communications Vol. 48 No. 78 p. 9756-9758 2012 Research paper (scientific journal)

  117. Fibrous supramolecular hemoprotein assemblies connected with synthetic heme dimer and apohemoprotein dimer

    Onoda, A., Takahashi, A., Oohora, K., Onuma, Y., Hayashi, T.

    Chemistry and Biodiversity Vol. 9 No. 9 p. 1684-1692 2012 Research paper (scientific journal)

  118. Reaction pathway and free energy profile for conversion of π-conjugation modes in porphyrin isomer

    Matsuo, T., Tohi, Y., Hayashi, T.

    Journal of Organic Chemistry Vol. 77 No. 20 p. 8946-8955 2012 Research paper (scientific journal)

  119. Supramolecular assembling systems formed by heme–heme pocket interactions in hemoproteins

    Oohora, K., Onoda, A., Hayashi, T.

    Chemical Communications Vol. 48 No. 96 p. 11714-11726 2012 Research paper (scientific journal)

  120. Preparation and reactivity of a tetranuclear Fe(II) core in the metallothionein α-domain

    Sano, Y., Onoda, A., Sakurai, R., Kitagishi, H., Hayashi, T.

    Journal of Inorganic Biochemistry Vol. 105 No. 5 p. 702-708 2011 Research paper (scientific journal)

  121. Thermal isomerization of N-bridged cobalt corrole complexes through a transiently formed axial carbenoid

    Chattopadhyay, P., Matsuo, T., Tsuji, T., Ohbayashi, J., Hayashi, T.

    Organometallics Vol. 30 No. 7 p. 1869-1873 2011 Research paper (scientific journal)

  122. Investigation of aromaticity and photophysical properties in [18]/[20]π porphycene derivatives

    Kim, K.S., Sung, Y.M., Matsuo, T., Hayashi, T., Kim, D.

    Chemistry - A European Journal Vol. 17 No. 28 p. 7882-7889 2011 Research paper (scientific journal)

  123. Precise design of artificial cofactors for enhancing peroxidase activity of myoglobin: Myoglobin mutant H64D reconstituted with a "single-winged cofactor" Is equivalent to native horseradish peroxidase in oxidation activity

    Matsuo, T., Fukumoto, K., Watanabe, T., Hayashi, T.

    Chemistry - An Asian Journal Vol. 6 No. 9 p. 2491-2499 2011 Research paper (scientific journal)

  124. A chemically-controlled supramolecular protein polymer formed by a myoglobin-based self-assembly system

    Oohora, K., Onoda, A., Kitagishi, H., Yamaguchi, H., Harada, A., Hayashi, T.

    Chemical Science Vol. 2 No. 6 p. 1033-1038 2011 Research paper (scientific journal)

  125. Crystal structure and spectroscopic studies of a stable mixed-valent state of the hemerythrin-like domain of a bacterial chemotaxis protein

    Onoda, A., Okamoto, Y., Sugimoto, H., Shiro, Y., Hayashi, T.

    Inorganic Chemistry Vol. 50 No. 11 p. 4892-4899 2011 Research paper (scientific journal)

  126. A hydrogenase model system based on the sequence of cytochrome c: Photochemical hydrogen evolution in aqueous media

    Sano, Y., Onoda, A., Hayashi, T.

    Chemical Communications Vol. 47 No. 29 p. 8229-8231 2011 Research paper (scientific journal)

  127. 1SE0920 Molecular Mechanism of Water Expelling System in the Initial Step of Cytochrome P450cam Catalytic Cycle(1SE Recent Advances in Structural Analyses of Funcitonal Mechanisms Based on Dynamics of Biological Reactions,The 48th Annual Meeting of the Biophysical Society of Japan)

    Hayashi Takashi

    Seibutsu Butsuri Vol. 50 No. 2 2010

    Publisher: The Biophysical Society of Japan General Incorporated Association
  128. DNA-binding hemoproteins tethering polyamine interface

    Onoda, A., Nagai, H., Koga, S., Hayashi, T.

    Bulletin of the Chemical Society of Japan Vol. 83 No. 4 p. 375-377 2010 Research paper (scientific journal)

  129. Supramolecular hemoprotein-gold nanoparticle conjugates

    Onoda, A., Ueya, Y., Sakamoto, T., Uematsu, T., Hayashi, T.

    Chemical Communications Vol. 46 No. 48 p. 9107-9109 2010 Research paper (scientific journal)

  130. Supramolecular protein-protein complexation via specific interaction between glycosylated myoglobin and sugar-binding protein

    Nagai, H., Onoda, A., Matsuo, T., Hayashi, T.

    Supramolecular Chemistry Vol. 22 No. 1 p. 57-64 2010 Research paper (scientific journal)

  131. Thermodynamically controlled supramolecular polymerization of cytochrome b<inf>562</inf>

    Kitagishi, H., Oohora, K., Hayashi, T.

    Biopolymers Vol. 91 No. 3 p. 194-200 2009 Research paper (scientific journal)

  132. Substrate binding induces structural changes in cytochrome P450cam

    Sakurai, K., Shimada, H., Hayashi, T., Tsukihara, T.

    Acta Crystallographica Section F: Structural Biology and Crystallization Communications Vol. 65 No. 2 p. 80-83 2009 Research paper (scientific journal)

  133. Self-assembly of one- And two-dimensional hemoprotein systems by polymerization through heme-heme pocket interactions

    Kitagishi, H., Kakikura, Y., Yamaguchi, H., Oohora, K., Harada, A., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 48 No. 7 p. 1271-1274 2009 Research paper (scientific journal)

  134. A role of the heme-7-propionate side chain in cytochrome P450cam as a gate for regulating the access of water molecules to the substrate-binding site

    Hayashi, T., Harada, K., Sakurai, K., Shimada, H., Hirota, S.

    Journal of the American Chemical Society Vol. 131 No. 4 p. 1398-+ 2009 Research paper (scientific journal)

  135. Meso-unsubstituted iron corrole in hemoproteins: Remarkable differences in effects on peroxidase activities between myoglobin and horseradish peroxidase

    Matsuo, T., Hayashi, A., Abe, M., Matsuda, T., Hisaeda, Y., Hayashi, T.

    Journal of the American Chemical Society Vol. 131 No. 42 p. 15124-+ 2009 Research paper (scientific journal)

  136. Electron transfer and oxidase activities in reconstituted hemoproteins with chemically modified cofactors

    Matsuo, T., Hayashi, T.

    Journal of Porphyrins and Phthalocyanines Vol. 13 No. 10 p. 1082-1089 2009 Research paper (scientific journal)

  137. Roles of heme-6-propionate side chain in monooxygenase cytochrome P450cam

    Sakurai Keisuke, Harada Katsuyoshi, Shimada Hideo, Hayashi Takashi

    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES Vol. 64 2008

  138. Oxidation reactivities of reconstituted hemoproteins with non-natural porphyrinoid cofactors

    Takashi Matsuo, Michiko Fujii, Masato Abe, Dai Murata, Takashi Hayashi

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN Vol. 128 p. 49-49 2008

  139. A supramolecular receptor of diatomic molecules (O<inf>2</inf>, CO, NO) in aqueous solution

    Kano, K., Itoh, Y., Kitagishi, H., Hayashi, T., Hirota, S.

    Journal of the American Chemical Society Vol. 130 No. 25 p. 8006-8015 2008 Research paper (scientific journal)

  140. Photocatalytic hydrogen generation using a protein-coated photosensitizer with anionic patches and a monocationic electron mediator

    Matsuo, T., Asano, A., Ando, T., Hisaeda, Y., Hayashi, T.

    Chemical Communications Vol. 3684-3686 No. 31 p. 3684-3686 2008 Research paper (scientific journal)

  141. Isolable iron(II)-porphycene derivative stabilized by introduction of trifluoromethyl groups on the ligand framework

    Ito, K., Matsuo, T., Aritome, I., Hisaeda, Y., Hayashi, T.

    Bulletin of the Chemical Society of Japan Vol. 81 No. 1 p. 76-83 2008 Research paper (scientific journal)

  142. Effect of peripheral trifluoromethyl groups in artificial iron porphycene cofactor on ligand binding properties of myoglobin

    Matsuo, T., Ito, K., Nakashima, Y., Hisaeda, Y., Hayashi, T.

    Journal of Inorganic Biochemistry Vol. 102 No. 2 p. 166-173 2008 Research paper (scientific journal)

  143. Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam

    Harada, K., Sakurai, K., Ikemura, K., Ogura, T., Hirota, S., Shimada, H., Hayashi, T.

    Journal of the American Chemical Society Vol. 130 No. 2 p. 432-+ 2008 Research paper (scientific journal)

  144. Exo-selective formation of bicyclic oxetanes in the photocycloaddition reaction of carbonyl compounds with vinylene carbonate: The important role of intermediary triplet diradicals in the stereoselectivity

    Abe, M., Taniguchi, K., Hayashi, T.

    Arkivoc Vol. 2007 No. 8 p. 58-65 2007 Research paper (scientific journal)

  145. Porphyrinoid chemistry in hemoprotein matrix: Detection and reactivities of iron(IV)-oxo species of porphycene incorporated into horseradish peroxidase

    Matsuo, T., Murata, D., Hisaeda, Y., Hori, H., Hayashi, T.

    Journal of the American Chemical Society Vol. 129 No. 43 p. 12906-+ 2007 Research paper (scientific journal)

  146. A structural isomer of nonaromatic porphyrin: Preparation of 20π-conjugated porphycene based on electronic perturbation

    Matsuo, T., Ito, K., Kanehisa, N., Hayashi, T.

    Organic Letters Vol. 9 No. 25 p. 5303-5306 2007 Research paper (scientific journal)

  147. Supramolecular hemoprotein linear assembly by successive interprotein heme-heme pocket interactions

    Kitagishi, H., Oohora, K., Yamaguchi, H., Sato, H., Matsuo, T., Harada, A., Hayashi, T.

    Journal of the American Chemical Society Vol. 129 No. 34 p. 10326-+ 2007 Research paper (scientific journal)

  148. Structure and ligand binding properties of myoglobins reconstituted with monodepropionated heme: Functional role of each heme propionate side chain

    Harada, K., Makino, M., Sugimoto, H., Hirota, S., Matsuo, T., Shiro, Y., Hisaeda, Y., Hayashi, T.

    Biochemistry Vol. 46 No. 33 p. 9406-9416 2007 Research paper (scientific journal)

  149. 鉄を含むタンパク質 : その多様な構造と反応性(ヘッドライン:生物無機化学-生体の中で働く金属イオンの化学-)

    松尾 貴史, 林 高史

    化学と教育 Vol. 54 No. 9 p. 474-477 2006

    Publisher: 公益社団法人 日本化学会
  150. Notable temperature effect on the stereoselectivity in the photochemical [2+2] cycloaddition reaction (Paternò-Büchi reaction) of 2,3-dihydrofuran-3-ol derivatives with benzophenone

    Abe, M., Terazawa, M., Nozaki, K., Masuyama, A., Hayashi, T.

    Tetrahedron Letters Vol. 47 No. 15 p. 2527-2530 2006 Research paper (scientific journal)

  151. Construction of glycosylated myoglobin by reconstitutional method

    Matsuo, T., Nagai, H., Hisaeda, Y., Hayashi, T.

    Chemical Communications Vol. 3131-3133 No. 29 p. 3131-3131 2006 Research paper (scientific journal)

  152. Experimental probe for hyperconjugative resonance contribution in stabilizing the singlet state of 2,2-dialkoxy-1,3-diyls: Regioselective 1,2-oxygen migration

    Abe, M., Hattori, M., Takegami, A., Masuyama, A., Hayashi, T., Seki, S., Tagawa, S.

    Journal of the American Chemical Society Vol. 128 No. 24 p. 8008-8014 2006 Research paper (scientific journal)

  153. A matrix isolation study of 2-isopropylidenecyclopentane-1,3-diyl (Berson-type diradical)

    Abe, M., Kawanami, S., Masuyama, A., Hayashi, T.

    Journal of Organic Chemistry Vol. 71 No. 17 p. 6607-6610 2006 Research paper (scientific journal)

  154. An extremely long-lived singlet 4,4-dimethoxy-3,5-diphenylpyrazolidine-3,5- diyl derivative: A notable nitrogen-atom effect on intra- and intermolecular reactivity

    Abe, M., Kubo, E., Nozaki, K., Matsuo, T., Hayashi, T.

    Angewandte Chemie - International Edition Vol. 45 No. 46 p. 7828-7831 2006 Research paper (scientific journal)

  155. Pathway of information transmission from heme to protein upon ligand binding/dissociation in myoglobin revealed by UV resonance raman spectroscopy

    Gao, Y., El-Mashtoly, S.F., Pal, B., Hayashi, T., Harada, K., Kitagawa, T.

    Journal of Biological Chemistry Vol. 281 No. 34 p. 24637-24646 2006 Research paper (scientific journal)

  156. Time-resolved Raman evidence for energy 'funneling' through propionate side chains in heme 'cooling' upon photolysis of carbonmonoxy myoglobin

    Gao, Y., Koyama, M., El-Mashtoly, S.F., Hayashi, T., Harada, K., Mizutani, Y., Kitagawa, T.

    Chemical Physics Letters Vol. 429 No. 1-3 p. 239-243 2006 Research paper (scientific journal)

  157. Crystal structure and peroxidase activity of myoglobin reconstituted with iron porphycene

    Hayashi, T., Murata, D., Makino, M., Sugimoto, H., Matsuo, T., Sato, H., Shiro, Y., Hisaeda, Y.

    Inorganic Chemistry Vol. 45 No. 26 p. 10530-10536 2006 Research paper (scientific journal)

  158. Organic/inorganic hybrid nanomaterials with vitamin B<inf>12</inf> functions

    Hisaeda, Y., Masuko, T., Hanashima, E., Hayashi, T.

    Science and Technology of Advanced Materials Vol. 7 No. 7 p. 655-661 2006 Research paper (scientific journal)

  159. Ligand binding properties of two kinds of reconstituted myoglobins with iron porphycene having propionates: Effect of β-pyrrolic position of two propionate side chains in porphycene framework

    Matsuo, T., Ikegami, T., Sato, H., Hisaeda, Y., Hayashi, T.

    Journal of Inorganic Biochemistry Vol. 100 No. 7 p. 1265-1271 2006 Research paper (scientific journal)

  160. Iron porphyrin-cyclodextrin supramolecular complex as a functional model of myoglobin in aqueous solution

    Kano, K., Kitagishi, H., Dagallier, C., Kodera, M., Matsuo, T., Hayashi, T., Hisaeda, Y., Hirota, S.

    Inorganic Chemistry Vol. 45 No. 11 p. 4448-4460 2006 Research paper (scientific journal)

  161. Functionalization of myoglobin

    Watanabe, Y., Hayashi, T.

    Progress in Inorganic Chemistry Vol. 54 p. 449-493 2005 Research paper (scientific journal)

  162. Preparation and O<inf>2</inf> binding study of myoglobin having a cobalt porphycene

    Matsuo, T., Tsuruta, T., Maehara, K., Sato, H., Hisaeda, Y., Hayashi, T.

    Inorganic Chemistry Vol. 44 No. 25 p. 9391-9396 2005 Research paper (scientific journal)

  163. Unusual ligand discrimination by a myoglobin reconstituted with a hydrophobic domain-linked heme

    Sato, H., Watanabe, M., Hisaeda, Y., Hayashi, T.

    Journal of the American Chemical Society Vol. 127 No. 1 p. 56-57 2005 Research paper (scientific journal)

  164. 2P074 UV Resonance Raman Studies on the Trigger of Structural Changes of Myoglobin upon Ligand Binding

    Gao Y., Pal Biswajit, Hayashi T., Harada K., Nakagawa T., Kitagawa T.

    Seibutsu Butsuri Vol. 44 2004

    Publisher: The Biophysical Society of Japan General Incorporated Association
  165. Enhancement of enzymatic activity for myoglobins by modification of heme-propionate side chains

    Hayashi, T., Sato, H., Matsuo, T., Matsuda, T., Hitomi, Y., Hisaeda, Y.

    Journal of Porphyrins and Phthalocyanines Vol. 8 No. 1-3 p. 255-264 2004 Research paper (scientific journal)

  166. Chemical properties of sperm whale myoglobins reconstituted with monopropionate hemins

    Hayashi, T., Nakagawa, T., Harada, K., Matsuo, T., Hitomi, Y., Hisaeda, Y.

    Chemistry Letters Vol. 33 No. 11 p. 1512-1513 2004 Research paper (scientific journal)

  167. Ligand binding properties of myoglobin reconstituted with iron porphycene: Unusual O<inf>2</inf> binding selectivity against CO binding

    Matsuo, T., Dejima, H., Hirota, S., Murata, D., Sato, H., Ikegami, T., Hori, H., Hisaeda, Y., Hayashi, T.

    Journal of the American Chemical Society Vol. 126 No. 49 p. 16007-16017 2004 Research paper (scientific journal)

  168. Residues in the distal heme pocket of neuroglobin: Implications for the multiple ligand binding steps

    Uno, T., Ryu, D., Tsutsumi, H., Tomisugi, Y., Ishikawa, Y., Wilkinson, A.J., Sato, H., Hayashi, T.

    Journal of Biological Chemistry Vol. 279 No. 7 p. 5886-5893 2004 Research paper (scientific journal)

  169. Hybridization of Modified-Heme Reconstitution and Distal Histidine Mutation to Functionalize Sperm Whale Myoglobin

    Sato, H., Hayashi, T., Ando, T., Hisaeda, Y., Ueno, T., Watanabe, Y.

    Journal of the American Chemical Society Vol. 126 No. 2 p. 436-437 2004 Research paper (scientific journal)

  170. Laser heating dynamics of poly(methyl methacrylate) films doped with aromatic molecules as revealed by analysis of diffusion of triplet states

    Fujiwara, H., Ishii, H., Ishiwata, T., Hayashi, T., Fukumura, H., Masuhara, H.

    Bulletin of the Chemical Society of Japan Vol. 76 No. 5 2003 Research paper (scientific journal)

  171. Synthesis, Characterization, and Autoreduction of a Highly Electron-Deficient Porphycenatoiron(III) with Trifluoromethyl Substituents

    Hayashi, T., Nakashima, Y., Ito, K., Ikegami, T., Aritome, I., Aoyagi, K., Ando, T., Hisaeda, Y.

    Inorganic Chemistry Vol. 42 No. 23 p. 7345-7347 2003 Research paper (scientific journal)

  172. Synthesis, structure, and chemical property of the first fluorine-containing porphycene

    Hayashi, T., Nakashima, Y., Ito, K., Ikegami, T., Aritome, I., Suzuki, A., Hisaeda, Y.

    Organic Letters Vol. 5 No. 16 p. 2845-2848 2003 Research paper (scientific journal)

  173. Enhancement of peroxygenase activity of horse heart myoglobin by modification of heme-propionate side chains

    Hayashi, T., Matsuda, T., Hisaeda, Y.

    Chemistry Letters Vol. 32 No. 6 p. 496-497 2003 Research paper (scientific journal)

  174. Iron twin-coronet porphyrins as models of myoglobin and hemoglobin: Amphibious electrostatic effects of overhanging hydroxyl groups for successful CO/O<inf>2</inf> discrimination

    Tani, F., Matsu-ura, M., Ariyama, K., Setoyama, T., Shimada, T., Kobayashi, S., Hayashi, T., Matsuo, T., Hisaeda, Y., Naruta, Y.

    Chemistry - A European Journal Vol. 9 No. 4 p. 862-870 2003 Research paper (scientific journal)

  175. Reductive activation of dioxygen by a myoglobin reconstituted with a flavohemin

    Matsuo, T., Hayashi, T., Hisaeda, Y.

    Journal of the American Chemical Society Vol. 124 No. 38 p. 11234-11235 2002 Research paper (scientific journal)

  176. Blue myoglobin reconstituted with an iron porphycene shows extremely high oxygen affinity

    Hayashi, T., Dejima, H., Matsuo, T., Sato, H., Murata, D., Hisaeda, Y.

    Journal of the American Chemical Society Vol. 124 No. 38 p. 11226-11227 2002 Research paper (scientific journal)

  177. Conversion of hemoprotein function by chemical modification

    Hayashi, T.

    Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry Vol. 60 No. 6 p. 573-580 2002 Research paper (scientific journal)

    Publisher: Society of Synthetic Organic Chemistry
  178. Contribution of heme-propionate side chains to structure and function of myoglobin: chemical approach by artificially created prosthetic groups

    Hayashi, T., Matsuo, T., Hitomi, Y., Okawa, K., Suzuki, A., Shiro, Y., Iizuka, T., Hisaeda, Y., Ogoshi, H.

    Journal of Inorganic Biochemistry Vol. 91 No. 1 p. 94-100 2002 Research paper (scientific journal)

  179. Chiral recognition and chiral sensing using zinc porphyrin dimers

    Hayashi, T., Aya, T., Nonoguchi, M., Mizutani, T., Hisaeda, Y., Kitagawa, S., Ogoshi, H.

    Tetrahedron Vol. 58 No. 14 p. 2803-2811 2002 Research paper (scientific journal)

  180. New functionalization of myoglobin by chemical modification of heme-propionates

    Hayashi, T., Hisaeda, Y.

    Accounts of Chemical Research Vol. 35 No. 1 p. 35-43 2002 Research paper (scientific journal)

  181. Electroorganic syntheses of macrocyclic lactones mediated by vitamin B-12 model complexes Part 17. Hydrophobic vitamin B-12

    Shimakoshi H, Nakazato A, Hayashi T, Tachi Y, Naruta Y, Hisaeda Y

    JOURNAL OF ELECTROANALYTICAL CHEMISTRY Vol. 507 No. 1-2 p. 170-176 2001/07/13

  182. Electroorganic syntheses of macrocyclic lactones mediated by vitamin B<inf>12</inf> model complexes: Part 17. Hydrophobic vitamin B<inf>12</inf>

    Shimakoshi, H., Nakazato, A., Hayashi, T., Tachi, Y., Naruta, Y., Hisaeda, Y.

    Journal of Electroanalytical Chemistry Vol. 507 No. 1-2 p. 170-176 2001 Research paper (scientific journal)

  183. Cobaltporphycenes as catalysts. The oxidation of vinyl ethers via the formation and dissociation of cobalt-carbon bonds

    Hayashi, T., Okazaki, K., Urakawa, N., Shimakoshi, H., Sessler, J.L., Vogel, E., Hisaeda, Y.

    Organometallics Vol. 20 No. 14 p. 3074-3078 2001 Research paper (scientific journal)

  184. Formation and cleavage of a dicobalt complex bridged with a pentamethylene group

    Shimakoshi, H., Koga, M., Hayashi, T., Tachi, Y., Naruta, Y., Hisaeda, Y.

    Chemistry Letters No. 4 p. 346-347 2001 Research paper (scientific journal)

    Publisher: Chemical Society of Japan
  185. Interprotein electron transfer reaction regulated by an artificial interface

    Hitomi, Y., Hayashi, T., Wada, K., Mizutani, T., Hisaeda, Y., Ogoshi, H.

    Angewandte Chemie - International Edition Vol. 40 No. 6 p. 1098-+ 2001 Research paper (scientific journal)

  186. Electrochemical reactions mediated by vitamin B<inf>12</inf> derivatives in organic solvents

    Hisaeda, Y., Nishioka, T., Inoue, Y., Asada, K., Hayashi, T.

    Coordination Chemistry Reviews Vol. 198 No. 1 p. 21-37 2000 Research paper (scientific journal)

  187. Introduction of a specific binding domain on myoglobin surface by new chemical modification

    Hayashi, T., Ando, T., Matsuda, T., Yonemura, H., Yamada, S., Hisaeda, Y.

    Journal of Inorganic Biochemistry Vol. 82 No. 1-4 p. 133-139 2000 Research paper (scientific journal)

  188. Synthesis and properties of alkylperoxocobalt(III) porphyrin and porphycene

    Hayashi, T., Okazaki, K., Shimakoshi, H., Tani, F., Naruta, Y., Hisaeda, Y.

    Chemistry Letters No. 2 p. 90-91 2000 Research paper (scientific journal)

    Publisher: Chemical Society of Japan
  189. Enhancement of peroxidase activity by use of reconstituted myoglobin

    T Hayashi, Y Hitomi, Y Hisaeda, S Kitagawa

    JOURNAL OF INORGANIC BIOCHEMISTRY Vol. 74 No. 1-4 p. 156-156 1999/04

  190. Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: Donor sugar-nucleotide based approach

    S Takayama, SJ Chung, Y Igarashi, Y Ichikawa, A Sepp, RI Lechler, JY Wu, T Hayashi, G Siuzdak, CH Wong

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 7 No. 2 p. 401-409 1999/02 Research paper (scientific journal)

  191. New approach to the construction of an artificial hemoprotein complex

    Hayashi, T., Hitomi, Y., Takimura, T., Tomokuni, A., Mizutani, T., Hisaeda, Y., Ogoshi, H.

    Coordination Chemistry Reviews Vol. 190-192 p. 961-974 1999 Research paper (scientific journal)

  192. Peroxidase activity of myoglobin is enhanced by chemical mutation of heme-propionates

    Hayashi, T., Hitomi, Y., Ando, T., Mizutani, T., Hisaeda, Y., Kitagawa, S., Ogoshi, H.

    Journal of the American Chemical Society Vol. 121 No. 34 p. 7747-7750 1999 Research paper (scientific journal)

  193. Synthesis and structure of tetraols with convergent and divergent arrays of hydroxy groups

    Takagi, H., Hayashi, T., Mizutani, T., Masuda, H., Ogoshi, H.

    Journal of the Chemical Society - Perkin Transactions 1 No. 13 p. 1885-1892 1999 Research paper (scientific journal)

    Publisher: Royal Society of Chemistry
  194. Structure and reactivity of reconstituted myoglobins: Interaction between protein and polar side chain of chemically modified hemin

    Hayashi, T., Takimura, T., Aoyama, Y., Hitomi, Y., Suzuki, A., Ogoshi, H.

    Inorganica Chimica Acta Vol. 275-276 No. 1-2 p. 159-167 1998 Research paper (scientific journal)

  195. Molecular recognition by novel macrotetracyclic cyclophanes having dipeptide segments

    Tanaka, A., Shimada, S., Hirohashi, T., Hayashi, T., Hisaeda, Y.

    Chemistry Letters No. 11 p. 1109-1110 1998 Research paper (scientific journal)

    Publisher: Chemical Society of Japan
  196. Interfacial recognition between reconstituted myoglobin having charged binding domain and electron acceptor via electrostatic interaction

    Hayashi, T., Tomokuni, A., Mizutani, T., Hisaeda, Y., Ogoshi, H.

    Chemistry Letters No. 12 p. 1229-1230 1998 Research paper (scientific journal)

    Publisher: Chemical Society of Japan
  197. Kinetic and thermodynamic analysis of induced-fit molecular recognition between tetraarylporphyrin and ubiquinone analogues

    Hayashi, T., Asai, T., Borgmeier, F.M., Hokazono, H., Ogoshi, H.

    Chemistry - A European Journal Vol. 4 No. 7 p. 1266-1274 1998 Research paper (scientific journal)

  198. Artificial protein-protein complexation between a reconstituted myoglobulin and cytochrome c

    Hayashi, T., Hitomi, Y., Ogoshi, H.

    Journal of the American Chemical Society Vol. 120 No. 20 p. 4910-4915 1998 Research paper (scientific journal)

  199. A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)galactose and evaluation of its interaction with galactosyltransferase

    T Hayashi, BW Murray, R Wang, CH Wong

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 5 No. 3 p. 497-500 1997/03 Research paper (scientific journal)

  200. Molecular modelling of electron transfer systems by noncovalently linked porphyrin-acceptor pairing

    Hayashi, T., Ogoshi, H.

    Chemical Society Reviews Vol. 26 No. 5 p. 355-364 1997 Research paper (scientific journal)

  201. Molecular recognition of ubiquinone analogues. Specific interaction between quinone and functional porphyrin via multiple hydrogen bonds

    Hayashi, T., Miyahara, T., Koide, N., Kato, Y., Masuda, H., Ogoshi, H.

    Journal of the American Chemical Society Vol. 119 No. 31 p. 7281-7290 1997 Research paper (scientific journal)

  202. Solvent effects on thermodynamic parameters for porphyrin-quinone interaction through multiple hydrogen bonding

    Hayashi, T., Miyahara, T., Koide, N., Ogoshi, H.

    Chemical Communications No. 19 p. 1865-1866 1997 Research paper (scientific journal)

    Publisher: Royal Society of Chemistry
  203. Conformational analysis of β-turn structure in tetrapeptides containing proline or proline analogs

    Hayashi, T., Asai, T., Ogoshi, H.

    Tetrahedron Letters Vol. 38 No. 17 p. 3039-3042 1997 Research paper (scientific journal)

  204. Molecular recognition of α,ω-diamines by metalloporphyrin dimer

    Hayashi, T., Nonoguchi, M., Aya, T., Ogoshi, H.

    Tetrahedron Letters Vol. 38 No. 9 p. 1603-1606 1997 Research paper (scientific journal)

  205. Photoinduccd electron transfer between multifunctional porphyrin and ubiquinone analogues linked by several hydrogen-bonding interactions

    Hayashi, T., Miyahara, T., Kumazaki, S., Ogoshi, H., Yoshihara, K.

    Angewandte Chemie (International Edition in English) Vol. 35 No. 17 p. 1964-1966 1996 Research paper (scientific journal)

  206. Synthesis of ring-fluorinated porphyrins and reconstitutional myoglobins with their iron complexes

    Suzuki, A., Tomizawa, T., Hayashi, T., Mizutani, T., Ogoshi, H.

    Bulletin of the Chemical Society of Japan Vol. 69 No. 10 p. 2923-2933 1996 Research paper (scientific journal)

  207. Synthetic strategies of multifunctional porphyrins as receptors

    Ogoshi, H., Kuroda, Y., Mizutani, T., Hayashi, T.

    Pure and Applied Chemistry Vol. 68 No. 7 p. 1411-1415 1996 Research paper (scientific journal)

    Publisher: Walter de Gruyter GmbH
  208. Anion complexation by bidentate Lewis acidic hosts, ortho-bis(fluorosilyl) benzenes

    Tamao, K., Hayashi, T., Ito, Y.

    Journal of Organometallic Chemistry Vol. 506 No. 1-2 p. 85-91 1996 Research paper (scientific journal)

  209. MOLECULAR RECOGNITION OF HORSE HEART APOMYOGLOBIN TO MONOPROPIONATE HEMIN - THERMODYNAMIC DETERMINATION OF 2 ORIENTATIONAL ISOMERS BY H-1-NMR SPECTRA

    T HAYASHI, Y HITOMI, A SUZUKI, T TAKIMURA, H OGOSHI

    CHEMISTRY LETTERS No. 10 p. 911-912 1995/10 Research paper (scientific journal)

  210. Silicon-carbon bond cleavage of pentacoordinate anionic silicates by N-bromosuccinimide

    Tamao, K., Hayashi, T., Ito, Y.

    Bulletin de la Societe Chimique de France Vol. 132 No. 5-6 p. 556-558 1995 Research paper (scientific journal)

  211. Photoinduced electron transfer from zinc porphyrin to a linked quinone in myoglobin

    Hayashi, T., Takimura, T., Ohara, T., Hitomi, Y., Ogoshi, H.

    Journal of the Chemical Society, Chemical Communications No. 24 p. 2503-2504 1995 Research paper (scientific journal)

  212. Photoinduced Singlet Electron Transfer in a Complex Formed from Zinc Myoglobin and Methyl Viologen: Artificial Recognition by a Chemically Modified Porphyrin

    Hayashi, T., Takimura, T., Ogoshi, H.

    Journal of the American Chemical Society Vol. 117 No. 46 p. 11606-11607 1995 Research paper (scientific journal)

  213. Molecular Recognition of Horse Heart Apomyoglobin for Monopropionate Hemin : Thermodynamic Determiuation of Two Orientational Isowers by 1H NMR Spectra

    Chem, Lett. No. 10 p. 911-912 1995

  214. Relationship between electron transfer and the structure of a quinone-linked zinc porphyrin with a flexible peptide spacer

    Hayashi, T., Takimura, T., Hitomi, Y., Ohara, T., Ogoshi, H.

    Journal of the Chemical Society, Chemical Communications No. 5 p. 545-546 1995 Research paper (scientific journal)

  215. PREPARATION AND BINDING-AFFINITY OF NEW PORPHYRIN HOST MOLECULE FOR UBIQUINONE ANALOGS

    T HAYASHI, T MIYAHARA, Y AOYAMA, M NONOGUCHI, H OGOSHI

    CHEMISTRY LETTERS No. 9 p. 1749-1752 1994/09 Research paper (scientific journal)

  216. Each dopant can absorb more than ten photons: Transient absorbance measurement at excitation laser wavelength in polymer ablation

    Fujiwara, H., Hayashi, T., Fukumura, H., Masuhara, H.

    Applied Physics Letters Vol. 64 No. 18 1994 Research paper (scientific journal)

  217. Intermolecular interaction between multifunctional porphyrin and ubiquinone analogues

    Hayashi, T., Miyahara, T., Aoyama, Y., Kobayashi, M., Ogoshi, H.

    Pure and Applied Chemistry Vol. 66 No. 4 p. 797-802 1994 Research paper (scientific journal)

  218. Carbene insertion into oxygenhydrogen bonds by metalloporphyrin catalysts

    Hayashi, T., Kato, T., Kaneko, T., Asai, T., Ogoshi, H.

    Journal of Organometallic Chemistry Vol. 473 No. 1-2 p. 323-327 1994 Research paper (scientific journal)

  219. Synthesis and structure of a new cis-1,3-dihydroxycyclohexane derivative having four convergent hydroxy groups

    Hayashi, T., Takagi, H., Masuda, H., Ogoshi, H.

    Journal of the Chemical Society, Chemical Communications No. 4 p. 364-365 1993 Research paper (scientific journal)

  220. Specific Molecular Recognition via Multipoint Hydrogen Bonding Ubiquinone Analogues—Porphyrin Having Four Convergent Hydroxyl Groups Pairing

    Hayashi, T., Miyahara, T., Hashizume, N., Ogoshi, H.

    Journal of the American Chemical Society Vol. 115 No. 5 p. 2049-2051 1993 Research paper (scientific journal)

  221. Dynamic Molecular Recognition in a Multifunctional Porphyrin and a Ubiquinone Analogue

    Hayashi, T., Asai, T., Hokazono, H., Ogoshi, H.

    Journal of the American Chemical Society Vol. 115 No. 25 p. 12210-12211 1993 Research paper (scientific journal)

  222. Pentacoordinate Anionic Bis(siliconates) Containing a Fluorine Bridge between Two Silicon Atoms. Synthesis, Solid-State Structures, and Dynamic Behavior in Solution

    Tamao, K., Hayashi, T., Ito, Y., Shiro, M.

    Organometallics Vol. 11 No. 6 p. 2099-2114 1992 Research paper (scientific journal)

  223. Electronic and Steric Effects in Pentacoordinate Anioni Diorganotrifluorosilicates: X-ray Structures and 13C NMR Studies for Evaluation of Charge Distribution in Aryl Groups on Silicon

    Tamao, K., Hayashi, T., Ito, Y., Shiro, M.

    Organometallics Vol. 11 No. 1 p. 182-191 1992 Research paper (scientific journal)

  224. HYDROGEN-PEROXIDE OXIDATION OF THE SILICON-CARBON BOND - MECHANISTIC STUDIES

    K TAMAO, T HAYASHI, Y ITO

    FRONTIERS OF ORGANOSILICON CHEMISTRY p. 197-207 1991 Research paper (international conference proceedings)

  225. Novel Pentacoordinate Anionic Silicate, [o-C<inf>6</inf>H<inf>4</inf>(SiPhF<inf>2</inf>)<inf>2</inf>F]-,K+-18-Crown-6, Containing a Bent Fluoride Bridge between Two Silicon Atoms

    Tamao, K., Hayashi, T., Ito, Y., Shiro, M.

    Journal of the American Chemical Society Vol. 112 No. 6 1990 Research paper (scientific journal)

  226. Additions and Corrections: Novel Pentacoordinate Anionic Silicate, [o-C<inf>6</inf>H<inf>4</inf>(SiPhF<inf>2</inf>)<inf>2</inf>F]-, K+.18-Crown-6, Containing a Bent Fluoride Bridge between Two Silicon Atoms (Journal of the American Chemical Society (1990) 112 (2422-2424))

    Tamao, K., Hayashi, T., Ito, Y., Shiro, M.

    Journal of the American Chemical Society Vol. 112 No. 14 p. 5679-5679 1990 Research paper (scientific journal)

  227. Structure and Reactivity of Hypercoordinate Silicon Compounds—Mechanism of Hydrogen Peroxide Oxidation of Silicon-Carbon Bonds—

    Tamao, K., Hayashi, T., Ito, Y.

    Nippon Kagaku Kaishi Vol. 1990 No. 5 p. 509-515 1990 Research paper (scientific journal)

  228. Ortho lithiation directed by amino groups on silicon in phenylsilane derivatives

    Tamao, K., Yao, H., Tsutsumi, Y., Abe, H., Hayashi, T., Ito, Y.

    Tetrahedron Letters Vol. 31 No. 20 p. 2925-2928 1990 Research paper (scientific journal)

  229. An efficient oxidative cleavage of carbon-silicon bonds by a dioxygen/hydroquinone system

    Tamao, K., Hayashi, T., Ito, Y.

    Tetrahedron Letters Vol. 30 No. 47 p. 6533-6536 1989 Research paper (scientific journal)

  230. Electroreductive Intermolecular Coupling of Ketones with Olefins

    Shono, T., Kashimura, S., Mori, Y., Hayashi, T., Soeiima, T., Yamaguchi, Y.

    Journal of Organic Chemistry Vol. 54 No. 26 p. 6001-6003 1989 Research paper (scientific journal)

  231. Oxidative cleavage of carbon-silicon bonds by dioxygen: Catalysis by a flavin-dihydronicotinamide redox system

    Tamao, K., Hayashi, T., Ito, Y.

    Journal of the Chemical Society, Chemical Communications No. 12 p. 795-797 1988 Research paper (scientific journal)

  232. 1H NMR Characterization of the System Cobalt(II)bis(histamino)-β-Cyclodextrin-Imidazole

    Takashi Hayashi

    Gazz. Chim. Ital. Vol. 118 No. 11 p. 777-781 1988 Research paper (scientific journal)

Misc. 30

  1. Chemical properties of reconstituted myoglobins with functionalized hemin derivatives

    T Hayashi, T Ando, T Matsuda, H Sato, T Matsuo, Y Hisaeda

    JOURNAL OF INORGANIC BIOCHEMISTRY Vol. 86 No. 1 p. 57-57 2001/08 Research paper, summary (international conference)

  2. Engineering of hemoproteins

    Takashi Hayashi, Shunsuke Kato

    Comprehensive Inorganic Chemistry III p. 215-230 2023

    Publisher: Elsevier
  3. CHAPTER 3: Myoglobin Derivatives Reconstituted with Modified Metal Porphyrinoids as Structural and Functional Models of the Cytochrome P450 Enzymes

    Hayashi, T., Oohora, K.

    RSC Metallobiology Vol. 2019-January No. 13 p. 63-78 2019

  4. Construction of a Hemoprotein Supramolecular 671 Polymer

    Hayashi, T.

    Kobunshi Vol. 66 No. 12 p. 671-672 2017

  5. Reconstitution of Heme Enzymes with Artificial Metalloporphyrinoids

    Oohora, K., Hayashi, T.

    Methods in Enzymology Vol. 580 p. 439-454 2016

  6. ヘムを介して配向担持されたセロビオースデヒドロゲナーゼ修飾バイオ電極の構築

    原田裕史, 小野田晃, 砂川直輝, 五十嵐圭日子, 林高史

    錯体化学会討論会講演要旨集 Vol. 65th 2015

  7. Artificial Metalloenzymes Containing an Organometallic Active Site

    Onoda, A., Hayashi, T., Salmain, M.

    Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging Vol. 9783527335275 p. 305-338 2015

    Publisher: Wiley Blackwell
  8. A Rhodium Complex-Linked beta Barrel Protein as a Hybrid Biocatalyst for Phenylacetylene Polymerization

    A. Onoda, K. Fukumoto, T. Hayashi

    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY Vol. 19 p. S569-S569 2014/03 Research paper, summary (international conference)

  9. Construction of a Methionine Synthase Model by Apomyoglobin Cobalt Corrin Complex

    T. Hayashi, Y. Morita, K. Oohora

    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY Vol. 19 p. S92-S92 2014/03 Research paper, summary (international conference)

  10. Incorporation of modified and artificial cofactors into naturally occurring protein scaffolds

    Oohora, K., Hayashi, T.

    Methods in Molecular Biology Vol. 1216 p. 251-263 2014

    Publisher: Methods in Molecular Biology
  11. Listeria monocytogenesのヘム取込み系におけるヘム結合タンパク質HupDの性質

    岡本泰典, 岡本泰典, 林高史, 澤井仁美, 青野重利

    日本化学会講演予稿集 Vol. 93rd No. 3 2013

  12. Generation of Functionalized Biomolecules using Hemoprotein Matrices with Small Protein Cavities for Incorporation of Cofactors

    Hayashi, T.

    Coordination Chemistry in Protein Cages: Principles, Design, and Applications p. 87-110 2013

    Publisher: John Wiley and Sons
  13. Construction of hemoprotein-based self-assembly systems

    Vol. 63 No. 6 p. 458-462 2012/06

    Publisher: 化学工業社
  14. Hemoproteins Reconstituted with Artificially Created Hemes

    Takashi Hayashi

    Handbook of Porphyrin Science Vol. 5 p. 1-69 2010

  15. Handbook of Porphyrin Science, Vol.5

    World Scientific Vol. 1-69 2010

  16. Exo-Selective formation of bicyclic oxetanes in the Paterno-Buchi reaction of vinylene carbonate: the important role of intermediary triplet diradicals in the stereoselectivity

    Manabu Abe, Kana Taniguchi, Takashi Hayashi

    Archive for Organic Chemistry (ARKIVOC) Vol. Vol. 2007. No. viii, 58-65 p. 58-65 2007 Rapid communication, short report, research note, etc. (scientific journal)

  17. ヘムタンパク質の高機能向上・改変--有機合成を駆使したタンパク質工学

    林 高史

    生産と技術 Vol. 58 No. 2 p. 36-39 2006

    Publisher: 生産技術振興協会
  18. Role of heme-propionate side chains in myoglobin function

    T Hayashi, T Matsuo, K Harada, Y Hisaeda, S Hirota, N Funasaki

    JOURNAL OF INORGANIC BIOCHEMISTRY Vol. 96 No. 1 p. 50-50 2003/07 Research paper, summary (international conference)

  19. Photoinduced electron transfer within an artificially created protein-protein complex

    T Ando, T Hayashi, H Sato, Y Hisaeda

    JOURNAL OF INORGANIC BIOCHEMISTRY Vol. 86 No. 1 p. 124-124 2001/08 Research paper, summary (international conference)

  20. New myoglobin reconstituted with an iron porphycene as a structural isomer of heme moiety

    H Dejima, T Hayashi, T Matsuo, Y Hisaeda

    JOURNAL OF INORGANIC BIOCHEMISTRY Vol. 86 No. 1 p. 200-200 2001/08 Research paper, summary (international conference)

  21. Molecular Modeling of Biological Electron Transfer via Molecular Recognition -Synthetic Receptor for Ubiquinone and Cytochrome c-

    Hayashi, T.

    Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry Vol. 56 No. 9 p. 745-754 1998

    Publisher: Society of Synthetic Organic Chemistry
  22. Complexation between Reconstituted Myoglobin and Cytochrome c

    J. Inorg. Biochem. Vol. 67 1997

  23. 合成ヘム再構成ミオグロビンを用いる光駆動電子移動反応

    有機合成化学研究所 Vol. 10 p. 83-90 1996

  24. Photoinduced Electron Transfer from Reconstitutd Myoglobin with Zinc Porphyrin to Viologen via Electrostatic Interaction

    Annual Report of Researcb Institute for Orgauic Synthetic Chemistry Vol. 10 p. 83-90 1996

  25. 動的分子認識過程解明のアプローチ

    有機合成化学研究所講演集 Vol. 9 p. 95-104 1995

  26. Approach to the Process of Dynamic Molecular Recognition

    Annual Report of Research Institute for Organic Synthetic Chemistry Vol. 9 p. 95-104 1995

  27. INTERMOLECULAR INTERACTION SYSTEM BETWEEN PORPHYRIN AND QUINONES - INDUCED FITTING MOLECULAR RECOGNITION AND ITS ELECTRON-TRANSFER

    T HAYASHI, T MIYAHARA, M KOBAYASHI, H HOKAZONO, H OGOSHI

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 203 p. 235-INOR 1992/04 Research paper, summary (international conference)

  28. SPECIFIC MOLECULAR RECOGNITION VIA MULTIPOINT HYDROGEN-BONDING - PORPHYRIN-COENZYME Q ANALOGS PAIRING

    HB OGOSHI, T HAYASHI, T MIYAHARA

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 203 p. 228-INOR 1992/04 Research paper, summary (international conference)

  29. 分子認識過程により制御された生体系電子移動のモデル化

    有機合成化学研究所 Vol. 6 p. 94-100 1992

  30. Artificial Model of Electron Transfer in Biological System controlled by Molecular Recognition Process

    Annual Report of Research Institute for Organic Synthetic Chemistry Vol. 6 p. 94-100 1992

Publications 6

  1. RSC Metallobiology

    Takashi Hayashi, Koji Oohora

    RSC 2019/01 Scholarly book

  2. Peroxidase and Peroxygenase Activities of a Myoglobin Reconstituted with an Iron Porphycene

    Biomolecular Chemistry, A Bridge for the Future, Proceeding of the ISBC2003, 2003

  3. Porphyrins and Metalloporphyrins as Receptor Models in Molecular Recognition

    The Porphyrin Handbook 2000

  4. Porphyrins and Metalloporphyrins as Receptor Models in Molecular Recognition

    The Porphyrin Handbook (Academic Press) 2000

  5. Hydrogen Peroxide Oxidation of the Silicon-Carbon Bond : Mechanistic Studies

    Frontiers of Organosilicon Chemistry 1991

  6. Hydrogen Peroxide Oxidation of the Silicon-Carbon Bond : Mechanistic Studies

    Frontiers of Organosilicon Chemistry 1991

Works 7

  1. ポルフィセン金属錯体を用いた新規触媒開発

    1999 - 2001

  2. Development of New Catalyst by Metalloporphycene

    1999 - 2001

  3. 修飾ヘムタンパク質の機能化

    2000 -

  4. 蛋白質フラスコを用いた高効率酵素型触媒

    2000 -

  5. New Functionalization of Modified Hemoproteins

    2000 -

  6. A Highly Effective Catalyst by Hemoprotein Matrix

    2000 -

  7. Preparation of 2-deoxy-2-fluoro-glycoside-bound nucleotides as glycosyltransferase inhibitors

    1998 -

Industrial Property Rights 1

  1. Preparation of 2-Deoxy-2-fluoro-glycoside-bound Nucleotides as Glycosyltransferase Inhibitors

Institutional Repository 4

Content Published in the University of Osaka Institutional Repository (OUKA)
  1. Photo-induced imine reduction by a photoredox biocatalyst consisting of a pentapeptide and a Ru bipyridine terpyridine complex

    Kano Ryusei, Oohora Koji, Hayashi Takashi

    Journal of Inorganic Biochemistry Vol. 259 2024/10/01

  2. Transition Behaviors of Isostructural Hydrogen-Bonded Frameworks Composed of Naphthalene, Quinoxaline, and Pyrazinopyrazine Derivatives

    Kubo Haruka, Konishi Shunsuke, Oketani Ryusei, Hayashi Takashi, Hisaki Ichiro

    Chemistry - A European Journal Vol. 30 No. 44 2024/08/06

  3. Redox Engineering of Myoglobin by Cofactor Substitution to Enhance Cyclopropanation Reactivity

    Kagawa Yoshiyuki, Oohora Koji, Himiyama Tomoki, Suzuki Akihiro, Hayashi Takashi

    Angewandte Chemie - International Edition Vol. 63 No. 36 2024/07/04

  4. Chitin- and Streptavidin- Mediated Affinity Purification Systems: A Screening Platform for Enzyme Discovery

    Kato Shunsuke, Takeuchi Koki, Iwaki Motonao, Miyazaki Kentaro, Honda Kohsuke, Hayashi Takashi

    Angewandte Chemie International Edition Vol. 145 2023/06/26