Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue.

Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Tomomi Nakamura, Koki Hashimoto, Jirouta Kitagaki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami

Aging　Vol. 15　No. 5　p. 1279-1305　2023/03/01　Research paper (scientific journal)

Periodontal Tissue Regeneration by Transplantation of Autologous Adipose Tissue-Derived Multi-Lineage Progenitor Cells With Carbonate Apatite.

Masahide Takedachi, Kohsuke Kawasaki, Keigo Sawada, Kazuma Sakura, Mari Murata, Junpei Shimomura, Kazuma Kawakami, Chiaki Morimoto, Koji Miki, Noboru Takeshita, Tomoaki Iwayama, Hanayuki Okura, Akifumi Matsuyama, Masahiro Saito, Masahiro Kitamura, Shinya Murakami

Cell transplantation　Vol. 32　p. 9636897231198296-9636897231198296　2023　Research paper (scientific journal)

Lipase‐a single‐nucleotide polymorphism rs143793106 is associated with increased risk of aggressive periodontitis by negative influence on the cytodifferentiation of human periodontal ligament cells

Masahiro Matsumoto, Chiharu Fujihara, Teerachate Nantakeeratipat, Jirouta Kitagaki, Yu Yamamoto, Satoru Yamada, Masahiro Kitamura, Shinya Murakami

Journal of Periodontal Research　2022/12/09　Research paper (scientific journal)

Structural analysis of melanosomes in living mammalian cells using scanning electron-assisted dielectric microscopy with deep neural network.

Tomoko Okada, Tomoaki Iwayama, Taku Ogura, Shinya Murakami, Toshihiko Ogura

Computational and structural biotechnology journal　Vol. 21　p. 506-518　2022/12　Research paper (scientific journal)

Study protocol for periodontal tissue regeneration with a mixture of autologous adipose-derived stem cells and platelet rich plasma: A multicenter, randomized, open-label clinical trial.

Morikuni Tobita, Yosuke Masubuchi, Yorimasa Ogata, Akio Mitani, Takeshi Kikuchi, Taku Toriumi, Jorge Luis Montenegro Raudales, Hiroshi Mizuno, Yuki Suzuki, Keiko Wakana, Hikari Yoneda, Reika Kamijo, Masahiro Kino-Oka, Tomohiro Morio, Kiyoshi Okada, Shinya Murakami, Masaki Honda

Regenerative therapy　Vol. 21　p. 436-441　2022/12　Research paper (scientific journal)

An exploratory clinical trial to evaluate the safety and efficacy of combination therapy of REGROTH® and Cytrans® granules for severe periodontitis with intrabony defects.

Masahiro Kitamura, Motozo Yamashita, Koji Miki, Kuniko Ikegami, Masahide Takedachi, Yoichiro Kashiwagi, Takenori Nozaki, Katsuyuki Yamanaka, Hijiri Masuda, Yoko Ishihara, Shinya Murakami

Regenerative therapy　Vol. 21　p. 104-113　2022/12　Research paper (scientific journal)

Periodontal tissue stem cells and mesenchymal stem cells in the periodontal ligament.

Tomoaki Iwayama, Hiromi Sakashita, Masahide Takedachi, Shinya Murakami

The Japanese dental science review　Vol. 58　p. 172-178　2022/11　Research paper (scientific journal)

Plap-1 lineage tracing and single-cell transcriptomics reveal cellular dynamics in the periodontal ligament.

Tomoaki Iwayama, Mizuho Iwashita, Kazuya Miyashita, Hiromi Sakashita, Shuji Matsumoto, Kiwako Tomita, Phan Bhongsatiern, Tomomi Kitayama, Kentaro Ikegami, Takashi Shimbo, Katsuto Tamai, Masanori A Murayama, Shuhei Ogawa, Yoichiro Iwakura, Satoru Yamada, Lorin E Olson, Masahide Takedachi, Shinya Murakami

Development (Cambridge, England)　Vol. 149　No. 19　2022/10/01　Research paper (scientific journal)

Evaluation of periodontitis-related tooth loss according to the new 2018 classification of periodontitis.

Masahide Takedachi, Yoshio Shimabukuro, Keigo Sawada, Mami Koshimizu, Kazuko Shinada, Harumi Asai, Ayumi Mizoguchi, Yuko Hayashi, Akina Tsukamoto, Midori Miyago, Fuuka Nishihara, Takako Nishihata, Michiyo Shimabukuro, Hiroyuki Kurakami, Tomoharu Sato, Yayoi Hamazaki, Tomoaki Iwayama, Chiharu Fujihara, Shinya Murakami

Scientific reports　Vol. 12　No. 1　p. 11893-11893　2022/07/13　Research paper (scientific journal)

Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx2.

Hiroko Yagi, Yoshifumi Takahata, Tomohiko Murakami, Yuri Nakaminami, Hiromasa Hagino, Shiori Yamamoto, Shinya Murakami, Kenji Hata, Riko Nishimura

Journal of bone and mineral metabolism　2022/06/28　Research paper (scientific journal)

Matrix Vesicle-Mediated Mineralization and Potential Applications.

T Iwayama, P Bhongsatiern, M Takedachi, S Murakami

Journal of dental research　p. 220345221103145-220345221103145　2022/06/19　Research paper (scientific journal)

An exploratory clinical trial to evaluate the safety and efficacy of combination therapy of REGROTH® and Cytrans® granules for severe periodontitis with intrabony defects

Masahiro Kitamura, Motozo Yamashita, Koji Miki, Kuniko Ikegami, Masahide Takedachi, Yoichiro Kashiwagi, Takenori Nozaki, Katsuyuki Yamanaka, Hijiri Masuda, Yoko Ishihara, Shinya Murakami

Regenerative Therapy　Vol. 21　p. 104-113　2022/06　Research paper (scientific journal)

Periodontal tissue regeneration by transplantation of autologous adipose tissue-derived multi-lineage progenitor cells.

Masahide Takedachi, Keigo Sawada, Kazuma Sakura, Chiaki Morimoto, Asae Hirai, Tomoaki Iwayama, Junpei Shimomura, Kohsuke Kawasaki, Chiharu Fujihara, Yoichiro Kashiwagi, Akimitsu Miyake, Tomomi Yamada, Hanayuki Okura, Akifumi Matsuyama, Masahiro Saito, Masahiro Kitamura, Shinya Murakami

Scientific reports　Vol. 12　No. 1　p. 8126-8126　2022/05/17　Research paper (scientific journal)

Predictive factors for tooth loss in older adults vary according to occlusal support: A 6-year longitudinal survey from the SONIC study.

Sato Hitomi, Kodai Hatta, Yuki Murotani, Toshihito Takahashi, Yasuyuki Gondo, Kei Kamide, Yukie Masui, Tatsuro Ishizaki, Mai Kabayama, Soshiro Ogata, Kenichi Matsuda, Yusuke Mihara, Motoyoshi Fukutake, Hiromasa Hagino, Kotaro Higashi, Suzuna Akema, Masahiro Kitamura, Shinya Murakami, Yoshinobu Maeda, Kazunori Ikebe

Journal of dentistry　p. 104088-104088　2022/03/05　Research paper (scientific journal)

Reciprocal role of PLAP-1 in HIF-1α-mediated responses to hypoxia.

Masahide Takedachi, Satomi Yamamoto, Kohsuke Kawasaki, Junpei Shimomura, Mari Murata, Chiaki Morimoto, Asae Hirai, Kazuma Kawakami, Phan Bhongsatiern, Tomoaki Iwayama, Keigo Sawada, Satoru Yamada, Shinya Murakami

Journal of periodontal research　2022/02/09　Research paper (scientific journal)

A cross-sectional study of relationships between periodontal disease and general health: The Hitachi Oral Healthcare Survey.

Shinsuke Kataoka, Mitsuo Kimura, Tsuguno Yamaguchi, Kenji Egashira, Yu Yamamoto, Yasushi Koike, Yuki Ogawa, Chika Fujiharu, Toshiko Namai, Kanako Taguchi, Momoko Takahashi, Asami Kameda, Tomoka Kasen, Asami Hano, Konomi Kubota, Masayuki Sato, Hiroaki Yamaga, Kaori Nohara, Mikiko Shirasawa, Chika Sekine, Maki Fukuda, Arisa Aoki, Yurina Takeuchi, Misaki Mugiyama, Kenta Mori, Keigo Sawada, Yoichiro Kashiwagi, Masahiro Kitamura, Takeshi Hayashi, Tohru Nakagawa, Shinya Murakami

BMC oral health　Vol. 21　No. 1　p. 644-644　2021/12/15　Research paper (scientific journal)

Author Correction: Porphyromonas gingivalis induces entero-hepatic metabolic derangements with alteration of gut microbiota in a type 2 diabetes mouse model (Scientific Reports, (2021), 11, 1, (18398), 10.1038/s41598-021-97868-2)

Yoichiro Kashiwagi, Shunsuke Aburaya, Naoyuki Sugiyama, Yuki Narukawa, Yuta Sakamoto, Masatomo Takahashi, Hayato Uemura, Rentaro Yamashita, Shotaro Tominaga, Satoko Hayashi, Takenori Nozaki, Satoru Yamada, Yoshihiro Izumi, Atsunori Kashiwagi, Takeshi Bamba, Yasushi Ishihama, Shinya Murakami

Scientific Reports　Vol. 11　No. 1　p. 20016-20016　2021/12　Research paper (scientific journal)

幹細胞移植による歯周組織再生療法における炭酸アパタイトの足場材としての有効性検証

川嵜 公輔, 竹立 匡秀, 沢田 啓吾, 下村 純平, 村田 真里, 河上 和馬, 三木 康史, 竹下 登, 佐倉 千萬, 松山 晃文, 大倉 華雪, 北村 正博, 村上 伸也

日本歯周病学会会誌　Vol. 63　No. 秋季特別　p. 122-122　2021/10

Porphyromonas gingivalis induces entero-hepatic metabolic derangements with alteration of gut microbiota in a type 2 diabetes mouse model.

Yoichiro Kashiwagi, Shunsuke Aburaya, Naoyuki Sugiyama, Yuki Narukawa, Yuta Sakamoto, Masatomo Takahashi, Hayato Uemura, Rentaro Yamashita, Shotaro Tominaga, Satoko Hayashi, Takenori Nozaki, Satoru Yamada, Yoshihiro Izumi, Atsunori Kashiwagi, Takeshi Bamba, Yasushi Ishihama, Shinya Murakami

Scientific reports　Vol. 11　No. 1　p. 18398-18398　2021/09/15　Research paper (scientific journal)

Mouse Model of Loeys-Dietz Syndrome Shows Elevated Susceptibility to Periodontitis via Alterations in Transforming Growth Factor-Beta Signaling.

Satoru Yamada, Kenichiro Tsushima, Masaki Kinoshita, Hiromi Sakashita, Tetsuhiro Kajikawa, Chiharu Fujihara, Hang Yuan, Shigeki Suzuki, Takayuki Morisaki, Shinya Murakami

Frontiers in physiology　Vol. 12　p. 715687-715687　2021/08　Research paper (scientific journal)

Periodontal inflamed surface area is associated with hs-CRP in septuagenarian Japanese adults in cross-sectional findings from the SONIC study.

Koji Miki, Masahiro Kitamura, Kodai Hatta, Kei Kamide, Yasuyuki Gondo, Motozo Yamashita, Masahide Takedachi, Takenori Nozaki, Chiharu Fujihara, Yoichiro Kashiwagi, Tomoaki Iwayama, Toshihito Takahashi, Hitomi Sato, Yuki Murotani, Mai Kabayama, Yasushi Takeya, Yoichi Takami, Hiroshi Akasaka, Koichi Yamamoto, Ken Sugimoto, Tatsuro Ishizaki, Yukie Masui, Hiromi Rakugi, Kazunori Ikebe, Shinya Murakami

Scientific reports　Vol. 11　No. 1　p. 14436-14436　2021/07/14　Research paper (scientific journal)

Long-term exposure to cigarette smoke influences characteristics in human gingival fibroblasts.

Mari Tatsumi, Manabu Yanagita, Motozo Yamashita, Shiori Hasegawa, Kuniko Ikegami, Masahiro Kitamura, Shinya Murakami

Journal of periodontal research　2021/05/31　Research paper (scientific journal)

The effect of aging on the nanostructure of murine alveolar bone and dentin.

Chika Akabane, Silvia Pabisch, Wolfgang Wagermaier, Andreas Roschger, Norio Tobori, Tomomichi Okano, Shinya Murakami, Peter Fratzl, Richard Weinkamer

Journal of bone and mineral metabolism　2021/04/11　Research paper (scientific journal)

Zbp1-positive cells are osteogenic progenitors in periodontal ligament.

Tsugumi Ueda, Tomoaki Iwayama, Kiwako Tomita, Shuji Matsumoto, Mizuho Iwashita, Phan Bhongsatiern, Hiromi Sakashita, Chiharu Fujihara, Masahide Takedachi, Shinya Murakami

Scientific reports　Vol. 11　No. 1　p. 7514-7514　2021/04/06　Research paper (scientific journal)

Aromatase inhibitor anastrozole modifies cellular functions in gingival fibroblasts and endothelial cells: possible periodontal complications of aromatase inhibitor treatment.

Shiori Hasegawa, Manabu Yanagita, Mari Tatsumi, Motozo Yamashita, Masahiro Kitamura, Shinya Murakami

Journal of periodontal research　2021/04/02　Research paper (scientific journal)

Hypoxia stimulates collagen hydroxylation in gingival fibroblasts and periodontal ligament cells.

Chiaki Morimoto, Masahide Takedachi, Kohsuke Kawasaki, Junpei Shimomura, Mari Murata, Asae Hirai, Kazuma Kawakami, Keigo Sawada, Tomoaki Iwayama, Shinya Murakami

Journal of periodontology　2021/03/04　Research paper (scientific journal)

Mice lacking PLAP-1/asporin counteracts high fat diet-induced metabolic disorder and alveolar bone loss by controlling adipose tissue expansion.

Hiromi Sakashita, Satoru Yamada, Masaki Kinoshita, Tetsuhiro Kajikawa, Tomoaki Iwayama, Shinya Murakami

Scientific reports　Vol. 11　No. 1　p. 4970-4970　2021/03/02　Research paper (scientific journal)

Effects of oxidative stress-induced increases in Zn2+ concentrations in human gingival epithelial cells.

Hiroko Yagi, Chiharu Fujihara, Shinya Murakami

Journal of periodontal research　2021/02/28　Research paper (scientific journal)

Autophagy facilitates type I collagen synthesis in periodontal ligament cells.

Tomomi Nakamura, Motozo Yamashita, Kuniko Ikegami, Mio Suzuki, Manabu Yanagita, Jirouta Kitagaki, Masahiro Kitamura, Shinya Murakami

Scientific reports　Vol. 11　No. 1　p. 1291-1291　2021/01/14　Research paper (scientific journal)

Nanoscale observation of PM2.5 incorporated into mammalian cells using scanning electron-assisted dielectric microscope.

Tomoko Okada, Tomoaki Iwayama, Shinya Murakami, Masaki Torimura, Toshihiko Ogura

Scientific reports　Vol. 11　No. 1　p. 228-228　2021/01/08　Research paper (scientific journal)

Expression of Asporin reprograms cancer cells to acquire resistance to oxidative stress.

Yuto Sasaki, Kurara Takagane, Takumi Konno, Go Itoh, Sei Kuriyama, Kazuyoshi Yanagihara, Masakazu Yashiro, Satoru Yamada, Shinya Murakami, Masamitsu Tanaka

Cancer science　2021/01/04　Research paper (scientific journal)

A large-scale observational study to investigate the current status of diabetic complications and their prevention in Japan (JDCP study 6): baseline dental and oral findings.

Koji Inagaki, Takeshi Kikuchi, Toshihide Noguchi, Akio Mitani, Keiko Naruse, Tatsuaki Matsubara, Masamitsu Kawanami, Jun Negishi, Yasushi Furuichi, Eiji Nemoto, Satoru Yamada, Hiromasa Yoshie, Koichi Tabeta, Sachiyo Tomita, Atsushi Saito, Sayaka Katagiri, Yuichi Izumi, Hiroshi Nitta, Takanori Iwata, Yukihiro Numabe, Matsuo Yamamoto, Nobuo Yoshinari, Tsuyoshi Fujita, Hidemi Kurihara, Fusanori Nishimura, Toshihiko Nagata, Hiromichi Yumoto, Toru Naito, Kazuyuki Noguchi, Koichi Ito, Shinya Murakami, Rimei Nishimura, Naoko Tajima

Diabetology international　Vol. 12　No. 1　p. 52-61　2021/01

A multicenter prospective cohort study on the effect of smoking cessation on periodontal therapies in Japan.

Yohei Nakayama, Koji Mizutani, Yuka Tsumanuma, Hiroyuki Yoshino, Norio Aoyama, Koji Inagaki, Manabu Morita, Yuichi Izumi, Shinya Murakami, Hidenori Yoshimura, Takanori Matsuura, Takashi Murakami, Matsuo Yamamoto, Nobuo Yoshinari, Masaru Mezawa, Yorimasa Ogata, Atsutoshi Yoshimura, Kanji Kono, Kosuke Maruyama, Soh Sato, Ryuji Sakagami, Hiroshi Ito, Yukihiro Numabe, Masahiko Nikaido, Takashi Hanioka, Kanichi Seto, Jinichi Fukuda, Saman Warnakulasuriya, Toru Nagao

Journal of oral science　2020/12/09　Research paper (scientific journal)

Will implants with a fixed dental prosthesis in the molar region enhance the longevity of teeth adjacent to distal free-end edentulous spaces?

Kodai Hatta, Toshihito Takahashi, Hitomi Sato, Shinya Murakami, Yoshinobu Maeda, Kazunori Ikebe

Clinical oral implants research　2020/12/05　Research paper (scientific journal)

Association of periodontal disease with atherosclerosis in 70-year-old Japanese older adults.

Masahiro Kitamura, Kazunori Ikebe, Kei Kamide, Yasuyuki Gondo, Motozo Yamashita, Masahide Takedachi, Takenori Nozaki, Chiharu Fujihara, Satoru Yamada, Yoichiro Kashiwagi, Koji Miki, Tomoaki Iwayama, Kodai Hatta, Yusuke Mihara, Yuko Kurushima, Hajime Takeshita, Mai Kabayama, Ryousuke Oguro, Tatsuo Kawai, Hiroshi Akasaka, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Tatsuro Ishizaki, Yasumichi Arai, Yukie Masui, Ryutaro Takahashi, Hiromi Rakugi, Yoshinobu Maeda, Shinya Murakami

Odontology　2020/11/04　Research paper (scientific journal)

Efficacy of FGF-2 in Periodontal Regeneration in A Case of Severe Intrabony Defect and Furcation Involvement With 15-Month Follow-up.

Shin-Ichi Takayama, Shinya Murakami

Clinical advances in periodontics　2020/10/19

A large-scale observational study to investigate the current status of diabetic complications and their prevention in Japan: Oral and dental findings at baseline -JDCP study 6-

Koji Inagaki, Takeshi Kikuchi, Toshihide Noguchi, Akio Mitani, Keiko Naruse, Tatsuaki Matsubara, Masamitsu Kawanami, Jun Negishi, Yasushi Furuichi, Eiji Nemoto, Satoru Yamada, Hiromasa Yoshie, Koichi Tabeta, Sachiyo Tomita, Atsushi Saito, Sayaka Katagiri, Yuichi Izumi, Hiroshi Nitta, Takanori Iwata, Yukihiro Numabe, Matsuo Yamamoto, Nobuo Yoshinari, Tsuyoshi Fujita, Hidemi Kurihara, Fusanori Nishimura, Toshihiko Nagata, Hiromichi Yumoto, Toru Naito, Kazuyuki Noguchi, Koichi Ito, Shinya Murakami, Rimei Nishimura, Naoko Tajima

Journal of the Japan Diabetes Society　Vol. 63　No. 4　p. 195-205　2020/10　Research paper (scientific journal)

Relative Contribution of Genetic and Environmental Factors to Periodontitis in Elderly Twins

IKEGAMI Kuniko, YAMASHITA Motozo, MIKI Koji, KURUSHIMA Yuko, KOUSAKA Takayuki, SUZUKI Mio, ENOKI Kaori, MATSUDA Kenichi, KITAMURA Masahiro, IKEBE Kazunori, Osaka Twin, Research Group, MURAKAMI Shinya

The Japanese Journal of Conservative Dentistry　Vol. 63　No. 3　p. 236-244　2020/06　Research paper (scientific journal)

高齢者双生児研究に基づく歯周病病態に関連する遺伝・環境要因の解析

池上 久仁子, 山下 元三, 三木 康史, 鈴木 美麻, 西川 有彩, 橋本 康樹, 森川 竜也, 竹下 登, 池邉 一典, 北村 正博, 村上 伸也

日本歯周病学会会誌　Vol. 62　No. 春季特別　p. 146-146　2020/05

Occlusal force predicted cognitive decline among 70- and 80-year-old Japanese: A 3-year prospective cohort study.

Kodai Hatta, Yasuyuki Gondo, Kei Kamide, Yukie Masui, Hiroki Inagaki, Takeshi Nakagawa, Ken-Ichi Matsuda, Chisato Inomata, Hajime Takeshita, Yusuke Mihara, Motoyoshi Fukutake, Masahiro Kitamura, Shinya Murakami, Mai Kabayama, Tatsuro Ishizaki, Yasumichi Arai, Ken Sugimoto, Hiromi Rakugi, Yoshinobu Maeda, Kazunori Ikebe

Journal of prosthodontic research　Vol. 64　No. 2　p. 175-181　2020/04　Research paper (scientific journal)

Development of Oral Care Chip, a novel device for quantitative detection of the oral microbiota associated with periodontal disease.

Ai Nozawa, Hiroyuki Oshima, Naoyuki Togawa, Takenori Nozaki, Shinya Murakami

PloS one　Vol. 15　No. 2　2020/02

大阪大学歯学部附属病院(口腔治療・歯周科)における塩基性線維芽細胞増殖因子(FGF-2)製剤を用いた歯周組織再生療法の治療成績

長谷川 詩織, 北村 正博, 今井 昴, 川嵜 公輔, 橋本 康樹, 花田 滉輔, 麻生 桃子, 野田 亜利紗, 辻井 翔一, 政近 健司, 藤田 翔子, 鈴木 美麻, 平井 麻絵, 森本 千晶, 八木 寛子, 池上 久仁子, 沢田 啓吾, 中村 友美, 岩山 智明, 柏木 陽一郎, 藤原 千春, 三木 康史, 竹立 匡秀, 山下 元三, 野崎 剛徳, 村上 伸也

特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集　Vol. 151回　p. 157-157　2019/10

Response to "Genetics of Periodontitis without Bias".

Masumoto R, Kitagaki J, Fujihara C, Matsumoto M, Miyauchi S, Asano Y, Imai A, Kobayashi K, Nakaya A, Yamashita M, Yamada S, Kitamura M, Murakami S

Journal of periodontal research　Vol. 54　No. 5　p. 455-456　2019/10

Osteoblastic lysosome plays a central role in mineralization.

Tomoaki Iwayama, Tomoko Okada, Tsugumi Ueda, Kiwako Tomita, Shuji Matsumoto, Masahide Takedachi, Satoshi Wakisaka, Takeshi Noda, Taku Ogura, Tomomichi Okano, Peter Fratzl, Toshihiko Ogura, Shinya Murakami

Science advances　Vol. 5　No. 7　2019/07

歯周病とインプラント周囲炎の新分類

藤原千春, 村上伸也

歯科評論 2月号　Vol. 916　No. 79(2)　2019/02

Periodontal Regeneration by Allogeneic Transplantation of Adipose Tissue Derived Multi-Lineage Progenitor Stem Cells in vivo.

Venkataiah VS, Handa K, Njuguna MM, Hasegawa T, Maruyama K, Nemoto E, Yamada S, Sugawara S, Lu L, Takedachi M, Murakami S, Okura H, Matsuyama A, Saito M

Scientific reports　Vol. 9　No. 1　2019/01

Fibroblast growth factor-2 inhibits CD40-mediated periodontal inflammation

Fujihara Chiharu, Kanai Yu, Masumoto Risa, Kitagaki Jirouta, Matsumoto Masahiro, Yamada Satoru, Kajikawa Tetsuhiro, Murakami Shinya

Journal of cellular physiology　2018/10

Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study.

Kodai Hatta, Kazunori Ikebe, Yasuyuki Gondo, Kei Kamide, Yukie Masui, Hiroki Inagaki, Takeshi Nakagawa, Ken-Ichi Matsuda, Taiji Ogawa, Chisato Inomata, Hajime Takeshita, Yusuke Mihara, Motoyoshi Fukutake, Masahiro Kitamura, Shinya Murakami, Mai Kabayama, Tatsuro Ishizaki, Yasumichi Arai, Ken Sugimoto, Hiromi Rakugi, Yoshinobu Maeda

Geriatrics & gerontology international　Vol. 18　No. 10　p. 1439-1446　2018/10　Research paper (scientific journal)

Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis

Masumoto Risa, Kitagaki Jirouta, Fujihara Chiharu, Matsumoto Masahiro, Miyauchi Shizuka, Asano Yoshihiro, Imai Atsuko, Kobayashi Kaori, Nakaya Akihiro, Yamashita Motozo, Yamada Satoru, Kitamura Masahiro, Murakami Shinya

Journal of periodontal research　2018/10

Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions

Iain L.C. Chapple, Brian L. Mealey, Thomas E. Van Dyke, P. Mark Bartold, Henrik Dommisch, Peter Eickholz, Maria L. Geisinger, Robert J. Genco, Michael Glogauer, Moshe Goldstein, Terrence J. Griffin, Palle Holmstrup, Georgia K. Johnson, Yvonne Kapila, Niklaus P. Lang, Joerg Meyle, Shinya Murakami, Jacqueline Plemons, Giuseppe A. Romito, Lior Shapira, Dimitris N. Tatakis, Wim Teughels, Leonardo Trombelli, Clemens Walter, Gernot Wimmer, Pinelopi Xenoudi, Hiromasa Yoshie

Journal of Clinical Periodontology　Vol. 45　p. S68-S77　2018/06/01　Research paper (international conference proceedings)

Fibrillin-1 insufficiency alters periodontal wound healing failure in a mouse model of Marfan syndrome

Keisuke Handa, Syouta Abe, V. Venkata Suresh, Yoshiyasu Fujieda, Masaki Ishikawa, Ai Orimoto, Yoko Kobayashi, Satoru Yamada, Satoko Yamaba, Shinya Murakami, Masahiro Saito

Archives of Oral Biology　Vol. 90　p. 53-60　2018/06/01　Research paper (scientific journal)

Dental plaque–induced gingival conditions

Shinya Murakami, Brian L. Mealey, Angelo Mariotti, Iain L.C. Chapple

Journal of Clinical Periodontology　Vol. 45　p. S17-S27　2018/06/01　Research paper (scientific journal)

喫煙により増悪する歯周病の病態形成に関する基礎的研究

柳田 学, 村上伸也

日本歯科医師会雑誌　Vol. 71　No. 1　p. 43-50　2018/04

Effects of paraoxonase 1 on the cytodifferentiation and mineralization of periodontal ligament cells

R. Masumoto, J. Kitagaki, M. Matsumoto, S. Miyauchi, C. Fujihara, M. Yamashita, S. Yamada, M. Kitamura, S. Murakami

Journal of Periodontal Research　Vol. 53　No. 2　p. 200-209　2018/04/01　Research paper (scientific journal)

Occlusal force is correlated with cognitive function directly as well as indirectly via food intake in community-dwelling older Japanese: From the SONIC study.

Kazunori Ikebe, Yasuyuki Gondo, Kei Kamide, Yukie Masui, Taturo Ishizaki, Yasumichi Arai, Hiroki Inagaki, Takeshi Nakagawa, Mai Kabayama, Hirochika Ryuno, Hitomi Okubo, Hajime Takeshita, Chisato Inomata, Yuko Kurushima, Yusuke Mihara, Kohdai Hatta, Motoyoshi Fukutake, Kaori Enoki, Taiji Ogawa, Ken-Ichi Matsuda, Ken Sugimoto, Ryosuke Oguro, Yoichi Takami, Norihisa Itoh, Yasushi Takeya, Koichi Yamamoto, Hiromi Rakugi, Shinya Murakami, Masahiro Kitamura, Yoshinobu Maeda

PloS one　Vol. 13　No. 1　2018/01　Research paper (scientific journal)

Relationship between atherosclerosis and occlusal support of natural teeth with mediating effect of atheroprotective nutrients: From the SONIC study

Sayaka Tada, Kazunori Ikebe, Kei Kamide, Yasuyuki Gondo, Chisato Inomata, Hajime Takeshita, Ken-ich Matsuda, Masahiro Kitamura, Shinya Murakami, Mai Kabayama, Ryousuke Oguro, Chikako Nakama, Tatsuo Kawai, Koichi Yamamoto, Ken Sugimoto, Ayumi Shintani, Takuma Ishihara, Yasumichi Arai, Yukie Masui, Ryutaro Takahashi, Hiromi Rakugi, Yoshinobu Maeda

PLOS ONE　Vol. 12　No. 8　2017/08　Research paper (scientific journal)

健康長寿の延伸には何がどの程度重要となるのか

池邉一典, 権藤恭之, 神出 計, 増井幸恵, 石崎達郎, 新井康通, 村上伸也, 前田芳信

歯界展望　Vol. 130　No. 1　p. 28-31　2017/07

エクソームシークエンスによる日本人侵襲性歯周炎の疾患関連遺伝子探索

北垣次郎太, 桝本梨沙, 宮内静香, 藤原千春, 村上伸也

日本歯周病学会誌　Vol. 59　No. 1　p. 1-9　2017/03　Research paper (scientific journal)

Sphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells

S. Miyauchi, J. Kitagaki, R. Masumoto, A. Imai, K. Kobayashi, A. Nakaya, S. Kawai, C. Fujihara, Y. Asano, M. Yamashita, M. Yanagita, S. Yamada, M. Kitamura, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 96　No. 3　p. 339-346　2017/03　Research paper (scientific journal)

Prevalence and risk factors for peri-implant diseases in Japanese adult dental patients

Yorimasa Ogata, Yohei Nakayama, Junichi Tatsumi, Takehiko Kubota, Shuichi Sato, Tetsuya Nishida, Yasuo Takeuchi, Tokuya Onitsuka, Ryuji Sakagami, Takenori Nozaki, Shinya Murakami, Naritoshi Matsubara, Maki Tanaka, Toshiaki Yoshino, Junya Ota, Taneaki Nakagawa, Yuichi Ishihara, Taichi Ito, Atsushi Saito, Keiko Yamaki, Etsuko Matsuzaki, Toshirou Hidaka, Daisuke Sasaki, Takashi Yaegashi, Tadashi Yasuda, Toshiaki Shibutani, Kazuyuki Noguchi, Hisao Araki, Noriharu Ikumi, Yukihiko Aoyama, Hideki Kogai, Kenji Nemoto, Shinji Deguchi, Takashi Takiguchi, Matsuo Yamamoto, Keita Inokuchi, Takatoshi Ito, Takashi Kado, Yasushi Furuichi, Mikimoto Kanazashi, Kazuhiro Gomi, Yukie Takagi, Keita Kubokawa, Nobuo Yoshinari, Yoshiaki Hasegawa, Tetsushi Hirose, Toshinaga Sase, Hirokazu Arita, Toshiro Kodama, Kitetsu Shin, Yuichi Izumi, Hiromasa Yoshie

JOURNAL OF ORAL SCIENCE　Vol. 59　No. 1　p. 1-11　2017/03　Research paper (scientific journal)

FGF-2 promotes initial osseointegration and enhances stability of implants with low primary stability

Toshie Nagayasu-Tanaka, Takenori Nozaki, Koji Miki, Keigo Sawada, Masahiro Kitamura, Shinya Murakami

CLINICAL ORAL IMPLANTS RESEARCH　Vol. 28　No. 3　p. 291-297　2017/03　Research paper (scientific journal)

Hypoxia-inducible factor-1 inhibits interleukin-6 and-8 production in gingival epithelial cells during hypoxia

M. Takedachi, M. Iyama, K. Sawada, K. Mori, S. Yamamoto, C. Morimoto, M. Yanagita, S. Murakami

JOURNAL OF PERIODONTAL RESEARCH　Vol. 52　No. 1　p. 127-134　2017/02　Research paper (scientific journal)

Useful Immunochromatographic Assay of Calprotectin in Gingival Crevicular Fluid for Diagnosis of Diseased Sites in Patients with Periodontal Diseases

Kido Jun-Ichi, Murakami Shinya, Kitamura Masahiro, Yanagita Manabu, Tabeta Koichi, Yamazaki Kazuhisa, Yoshie Hiromasa, Watanabe Hisashi, Izumi Yuichi, Suda Reiko, Yamamoto Matsuo, Shiba Hideki, Fujita Tsuyoshi, Kurihara Hidemi, Mizuno Mitsuharu, Mishima Akihiro, Kawahara Nobumasa, Hashimoto Kazuhiro, Naruishi Koji, Nagata Toshihiko

Journal of periodontology　2017

The nanostructure of murine alveolar bone and its changes due to type 2 diabetes

Silvia Pabisch, Chika Akabane, Wolfgang Wagermaier, Andreas Roschger, Taku Ogura, Ryo Hyodo, Shinsuke Kataoka, Norio Tobori, Tomomichi Okano, Shinya Murakami, Peter Fratzl, Richard Weinkamer

JOURNAL OF STRUCTURAL BIOLOGY　Vol. 196　No. 2　p. 223-231　2016/11　Research paper (scientific journal)

Proinflammatory M1 Macrophages Inhibit RANKL-Induced Osteoclastogenesis

Tsuguno Yamaguchi, Alexandru Movila, Shinsuke Kataoka, Wichaya Wisitrasameewong, Montserrat Ruiz Torruella, Michiaki Murakoshi, Shinya Murakami, Toshihisa Kawai

INFECTION AND IMMUNITY　Vol. 84　No. 10　p. 2802-2812　2016/10　Research paper (scientific journal)

Human odontogenic epithelial cells derived from epithelial rests of Malassez possess stem cell properties

Takaaki Tsunematsu, Natsumi Fujiwara, Maki Yoshida, Yukihiro Takayama, Satoko Kujiraoka, Guangying Qi, Masae Kitagawa, Tomoyuki Kondo, Akiko Yamada, Rieko Arakaki, Mutsumi Miyauchi, Ikuko Ogawa, Yoshihiro Abiko, Hiroki Nikawa, Shinya Murakami, Takashi Takata, Naozumi Ishimaru, Yasusei Kudo

LABORATORY INVESTIGATION　Vol. 96　No. 10　p. 1063-1075　2016/10　Research paper (scientific journal)

High glucose-induced oxidative stress increases IL-8 production in human gingival epithelial cells

Y. Kashiwagi, M. Takedachi, K. Mori, M. Kubota, S. Yamada, M. Kitamura, S. Murakami

ORAL DISEASES　Vol. 22　No. 6　p. 578-584　2016/09　Research paper (scientific journal)

Transcriptome Reveals Cathepsin K in Periodontal Ligament Differentiation

S. Yamada, N. Ozaki, K. Tsushima, S. Yamaba, C. Fujihara, T. Awata, H. Sakashita, T. Kajikawa, J. Kitagaki, M. Yamashita, M. Yanagita, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 95　No. 9　p. 1026-1033　2016/08　Research paper (scientific journal)

A Putative Association of a Single Nucleotide Polymorphism in GPR126 with Aggressive Periodontitis in a Japanese Population

Jirouta Kitagaki, Shizuka Miyauchi, Yoshihiro Asano, Atsuko Imai, Shinji Kawai, Ikumi Michikami, Motozo Yamashita, Satoru Yamada, Masahiro Kitamura, Shinya Murakami

PLOS ONE　Vol. 11　No. 8　2016/08　Research paper (scientific journal)

Periodontal tissue engineering by FGF-2:Its present status and future outlook

Murakami Shinya

Clinical calcium　Vol. 26　No. 7　2016/07

Long-term Observation of Regenerated Periodontium Induced by FGF-2 in the Beagle Dog 2-Wall Periodontal Defect Model

Jun Anzai, Toshie Nagayasu-Tanaka, Akio Terashima, Taiji Asano, Satoru Yamada, Takenori Nozaki, Masahiro Kitamura, Shinya Murakami

PLOS ONE　Vol. 11　No. 7　2016/07　Research paper (scientific journal)

Metabolomic Analysis of Gingival Crevicular Fluid Using Gas Chromatography/Mass Spectrometry

Ozeki Miho, Nozaki Takenori, Aoki Jun, Bamba Takeshi, Jensen Kirk R, Murakami Shinya, Toyoda Michisato

Mass spectrometry (Tokyo, Japan)　Vol. 5　No. 1　2016/06

The Effects of Cigarette Smoke Condensate and Nicotine on Periodontal Tissue in a Periodontitis Model Mouse

Mikiko Kubota, Manabu Yanagita, Kenta Mori, Shiori Hasegawa, Motozo Yamashita, Satoru Yamada, Masahiro Kitamura, Shinya Murakami

PLOS ONE　Vol. 11　No. 5　2016/05　Research paper (scientific journal)

Periodontal destruction and trends in periodontal treatment for patients

Yanagita Manabu, Murakami Shinya

Clinical calcium　Vol. 26　No. 5　2016/05

Randomized Placebo-Controlled and Controlled Non-Inferiority Phase III Trials Comparing Trafermin, a Recombinant Human Fibroblast Growth Factor 2, and Enamel Matrix Derivative in Periodontal Regeneration in Intrabony Defects

Masahiro Kitamura, Motoki Akamatsu, Masamitsu Kawanami, Yasushi Furuichi, Takeo Fujii, Mari Mori, Kazushi Kunimatsu, Hidetoshi Shimauchi, Yorimasa Ogata, Matsuo Yamamoto, Taneaki Nakagawa, Shuichi Sato, Koichi Ito, Takefumi Ogasawara, Yuichi Izumi, Kazuhiro Gomi, Kazuhisa Yamazaki, Hiromasa Yoshie, Mitsuo Fukuda, Toshihide Noguchi, Shogo Takashiba, Hidemi Kurihara, Toshihiko Nagata, Takafumi Hamachi, Katsumasa Maeda, Makoto Yokota, Ryuji Sakagami, Yoshitaka Hara, Kazuyuki Noguchi, Toshi Furuuchi, Takashi Sasano, Enyu Imai, Masatoshi Ohmae, Hayuru Koizumi, Mitsuru Watanuki, Shinya Murakami

JOURNAL OF BONE AND MINERAL RESEARCH　Vol. 31　No. 4　p. 806-814　2016/04　Research paper (scientific journal)

PLAP-1/Asporin Regulates TLR2-and TLR4-induced Inflammatory Responses

S. Yamaba, S. Yamada, T. Kajikawa, T. Awata, H. Sakashita, K. Tsushima, C. Fujihara, M. Yanagita, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 94　No. 12　p. 1706-1714　2015/12　Research paper (scientific journal)

Resveratrol suppresses the inflammatory responses of human gingival epithelial cells in a SIRT1 independent manner

T. Minagawa, T. Okui, N. Takahashi, T. Nakajima, K. Tabeta, S. Murakami, K. Yamazaki

JOURNAL OF PERIODONTAL RESEARCH　Vol. 50　No. 5　p. 586-593　2015/10　Research paper (scientific journal)

PLAP-1/Asporin Positively Regulates FGF-2 Activity

T. Awata, S. Yamada, K. Tsushima, H. Sakashita, S. Yamaba, T. Kajikawa, M. Yamashita, M. Takedachi, M. Yanagita, M. Kitamura, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 94　No. 10　p. 1417-1424　2015/10　Research paper (scientific journal)

Trophic factors from adipose tissue-derived multi-lineage progenitor cells promote cytodifferentiation of periodontal ligament cells.

Keigo Sawada, Masahide Takedachi, Satomi Yamamoto, Chiaki Morimoto, Masao Ozasa, Tomoaki Iwayama, Chun Man Lee, Hanayuki Okura, Akifumi Matsuyama, Masahiro Kitamura, Shinya Murakami

Biochemical and biophysical research communications　Vol. 464　No. 1　p. 299-305　2015/08/14

Necrosis-induced TLR3 Activation Promotes TLR2 Expression in Gingival Cells

K. Mori, M. Yanagita, S. Hasegawa, M. Kubota, M. Yamashita, S. Yamada, M. Kitamura, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 94　No. 8　p. 1149-1157　2015/08　Research paper (scientific journal)

Time-lapse Raman imaging of osteoblast differentiation

Aya Hashimoto, Yoshinori Yamaguchi, Liang-da Chiu, Chiaki Morimoto, Katsumasa Fujita, Masahide Takedachi, Satoshi Kawata, Shinya Murakami, Eiichi Tamiya

SCIENTIFIC REPORTS　Vol. 5　2015/07　Research paper (scientific journal)

Changes in the Distribution of Periodontal Nerve Fibers during Dentition Transition in the Cat

Koji Miki, Shiho Honma, Satomi Ebara, Kenzo Kumamoto, Shinya Murakami, Satoshi Wakisaka

PLOS ONE　Vol. 10　No. 6　2015/06　Research paper (scientific journal)

Action Mechanism of Fibroblast Growth Factor-2 (FGF-2) in the Promotion of Periodontal Regeneration in Beagle Dogs

Toshie Nagayasu-Tanaka, Jun Anzai, Shu Takaki, Noriko Shiraishi, Akio Terashima, Taiji Asano, Takenori Nozaki, Masahiro Kitamura, Shinya Murakami

PLOS ONE　Vol. 10　No. 6　2015/06　Research paper (scientific journal)

TGF-Beta Negatively Regulates the BMP2-Dependent Early Commitment of Periodontal Ligament Cells into Hard Tissue Forming Cells

Takanobu Kawahara, Motozo Yamashita, Kuniko Ikegami, Tomomi Nakamura, Manabu Yanagita, Satoru Yamada, Masahiro Kitamura, Shinya Murakami

PLOS ONE　Vol. 10　No. 5　2015/05　Research paper (scientific journal)

Examination of the Relationship between Oral Health and Arterial Sclerosis without Genetic Confounding through the Study of Older Japanese Twins

Yuko Kurushima, Kazunori Ikebe, Ken-ichi Matsuda, Kaori Enoki, Soshiro Ogata, Motozo Yamashita, Shinya Murakami, Yoshinobu Maeda

PLOS ONE　Vol. 10　No. 5　2015/05　Research paper (scientific journal)

Effects of the proteasome inhibitor, bortezomib, on cytodifferentiation and mineralization of periodontal ligament cells

J. Kitagaki, S. Miyauchi, C. J. Xie, M. Yamashita, S. Yamada, M. Kitamura, S. Murakami

JOURNAL OF PERIODONTAL RESEARCH　Vol. 50　No. 2　p. 248-255　2015/04　Research paper (scientific journal)

Cyclic depsipeptides as potential cancer therapeutics

Jirouta Kitagaki, Genbin Shi, Shizuka Miyauchi, Shinya Murakami, Yili Yang

ANTI-CANCER DRUGS　Vol. 26　No. 3　p. 259-271　2015/03

Emerging Regenerative Approaches for Periodontal Reconstruction: A Consensus Report From the AAP Regeneration Workshop

David L. Cochran, Charles M. Cobb, Jill D. Bashutski, Yong-Hee Patricia Chun, Zhao Lin, George A. Mandelaris, Bradley S. McAllister, Shinya Murakami, Hector F. Rios

JOURNAL OF PERIODONTOLOGY　Vol. 86　No. 2　p. S153-S156　2015/02　Research paper (scientific journal)

Emerging Regenerative Approaches for Periodontal Reconstruction: Practical Applications From the AAP Regeneration Workshop

Rios Hector F, Bashutski Jill D, McAllister Bradley S, Murakami Shinya, Cobb Charles M, Chun Yong-Hee Patricia, Lin Zhao, Mandelaris George A, Cochran David L

Clinical advances in periodontics　Vol. 5　No. 1　2015/02

Influence of genetic and environmental factors on oral diseases and function in aged twins

Y. Kurushima, K. Ikebe, K. Matsuda, K. Enoki, S. Ogata, M. Yamashita, S. Murakami, K. Hayakawa, Y. Maeda

JOURNAL OF ORAL REHABILITATION　Vol. 42　No. 1　p. 49-56　2015/01　Research paper (scientific journal)

Group C. Initiator paper. Periodontal regeneration--fact or fiction?

Bartold P. M

Journal of the International Academy of Periodontology　Vol. 17　No. 1 Suppl　2015/01

Effects of an Ascorbic Acid-Derivative Dentifrice in Patients With Gingivitis: A Double-Masked, Randomized, Controlled Clinical Trial

Yoshio Shimabukuro, Yohei Nakayama, Yorimasa Ogata, Kaoru Tamazawa, Hidetoshi Shimauchi, Tetsuya Nishida, Koichi Ito, Takashi Chikazawa, Shinsuke Kataoka, Shinya Murakami

JOURNAL OF PERIODONTOLOGY　Vol. 86　No. 1　p. 27-35　2015/01　Research paper (scientific journal)

Isolation and characterization of the human immature osteoblast culture system from the alveolar bones of aged donors for bone regeneration therapy

Makoto Aino, Eisaku Nishida, Yoshiyasu Fujieda, Ai Orimoto, Akio Mitani, Toshihide Noguchi, Hatsune Makino, Shinya Murakami, Akihiro Umezawa, Toshiyuki Yoneda, Masahiro Saito

EXPERT OPINION ON BIOLOGICAL THERAPY　Vol. 14　No. 12　p. 1731-1744　2014/12　Research paper (scientific journal)

Dentistry in the 21st century: challenges of a globalising world

Mikako Hayashi, Markus Haapasalo, Satoshi Imazato, Jae Il Lee, Yasuko Momoi, Shinya Murakami, Helen Whelton, Nairn Wilson

INTERNATIONAL DENTAL JOURNAL　Vol. 64　No. 6　p. 333-342　2014/12　Research paper (scientific journal)

Association of periodontal status with occlusal force and food acceptability in 70-year-old adults: from SONIC Study

T. Okada, K. Ikebe, C. Inomata, H. Takeshita, M. Uota, Y. Mihara, K. Matsuda, M. Kitamura, S. Murakami, Y. Gondo, K. Kamide, Y. Masui, R. Takahashi, Y. Arai, Y. Maeda

JOURNAL OF ORAL REHABILITATION　Vol. 41　No. 12　p. 912-919　2014/12　Research paper (scientific journal)

Epithelial TRPV1 Signaling Accelerates Gingival Epithelial Cell Proliferation

N. Takahashi, Y. Matsuda, H. Yamada, K. Tabeta, T. Nakajima, S. Murakami, K. Yamazaki

JOURNAL OF DENTAL RESEARCH　Vol. 93　No. 11　p. 1141-1147　2014/11　Research paper (scientific journal)

Characterization of a Novel Periodontal Ligament-specific Periostin Isoform

S. Yamada, T. Tauchi, T. Awata, K. Maeda, T. Kajikawa, M. Yanagita, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 93　No. 9　p. 891-897　2014/09　Research paper (scientific journal)

Significance of occlusal force for dietary fibre and vitamin intakes in independently living 70-year-old Japanese: from SONIC Study

Chisato Inomata, Kazunori Ikebe, Ryosuke Kagawa, Hitomi Okubo, Satoshi Sasaki, Tadashi Okada, Hajime Takeshita, Sayaka Tada, Ken-ichi Matsuda, Yuko Kurushima, Masahiro Kitamura, Shinya Murakami, Yasuyuki Gondo, Kei Kamide, Yukie Masui, Ryutaro Takahashi, Yasumichi Arai, Yoshinobu Maeda

JOURNAL OF DENTISTRY　Vol. 42　No. 5　p. 556-564　2014/05　Research paper (scientific journal)

Iron plays a key role in the cytodifferentiation of human periodontal ligament cells

J. Hou, S. Yamada, T. Kajikawa, N. Ozaki, T. Awata, S. Yamaba, C. Fujihara, S. Murakami

JOURNAL OF PERIODONTAL RESEARCH　Vol. 49　No. 2　p. 260-267　2014/04　Research paper (scientific journal)

Inhibitory Effects of PLAP-1/asporin on Periodontal Ligament Cells

T. Kajikawa, S. Yamada, T. Tauchi, T. Awata, S. Yamaba, C. Fujihara, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 93　No. 4　p. 400-405　2014/04　Research paper (scientific journal)

In situ Raman imaging of osteoblastic mineralization

Aya Hashimoto, Liang-da Chiu, Keigo Sawada, Tomohiko Ikeuchi, Katsumasa Fujita, Masahide Takedachi, Yoshinori Yamaguchi, Satoshi Kawata, Shinya Murakami, Eiichi Tamiya

JOURNAL OF RAMAN SPECTROSCOPY　Vol. 45　No. 2　p. 157-161　2014/02　Research paper (scientific journal)

Cooperative Effects of FGF-2 and VEGF-A in Periodontal Ligament Cells

M. Yanagita, Y. Kojima, M. Kubota, K. Mori, M. Yamashita, S. Yamada, M. Kitamura, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 93　No. 1　p. 89-95　2014/01　Research paper (scientific journal)

The usefulness of a haptic virtual reality simulator with repetitive training to teach caries removal and periodontal pocket probing skills

Satoshi Yamaguchi, Yoshinori Yoshida, Hiroshi Noborio, Shinya Murakami, Satoshi Imazato

DENTAL MATERIALS JOURNAL　Vol. 32　No. 5　p. 847-852　2013/10　Research paper (scientific journal)

Periodontal tissue regeneration by transplantation of adipose tissue-derived stem cells

Masahide Takedachi, Keigo Sawada, Satomi Yamamoto, Masao Ozasa, Yoshio Shimabukuro, Masahiro Kitamura, Shinya Murakami

Journal of Oral Biosciences　Vol. 55　No. 3　p. 137-142　2013/08　Research paper (scientific journal)

The Longitudinal Effects of Supportive Periodontal Therapy for the Survival of Teeth in Periodontal Patients

YAMABA Satoko, MATSUMOTO Wataru, IYAMA Mitsuyoshi, HIGASHIYAMA Yayoi, MATSUI Miki, YAMAGUCHI Taishi, OZAKI Nobuhiro, KOJIMA Yuko, OHARA Hiroyuki, KAJIKAWA Tetsuhiro, OZASA Masao, KITAMURA Masahiro, KASHIWAGI Yoichiro, MIKI Koji, TAUCHI Takushi, TAKEDACHI Masahide, KITAGAKI Jirota, YAMASHITA Motozo, YANAGITA Manabu, NOZAKI Takenori, YAMADA Satoru, SHIMABUKURO Yoshio, MIYAZATO Kousuke, MURAKAMI Shinya, KURIHARA Akiko, SHIMA Miwako, KUBOTA Mikiko, NISHIMURA Makoto, YAMAMOTO Atsushi, YOSHIOKA Eri

The Japanese Journal of Conservative Dentistry　Vol. 56　No. 1　p. 40-47　2013/02

Periodontal Regeneration and FGF-2

Y Kojima, M Yanagita, S Yamada, M Kitamura, S Murakami

Inflammation and Regeneration　Vol. 33　No. 1　p. 72-77　2013/01　Research paper (scientific journal)

Assessment of the Plasma/Serum IgG Test to Screen for Periodontitis

C. Kudo, K. Naruishi, H. Maeda, Y. Abiko, T. Hino, M. Iwata, C. Mitsuhashi, S. Murakami, T. Nagasawa, T. Nagata, S. Yoneda, Y. Nomura, T. Noguchi, Y. Numabe, Y. Ogata, T. Sato, H. Shimauchi, K. Yamazaki, A. Yoshimura, S. Takashiba

JOURNAL OF DENTAL RESEARCH　Vol. 91　No. 12　p. 1190-1195　2012/12　Research paper (scientific journal)

Role of ferritin in the cytodifferentiation of periodontal ligament cells

Jianxia Hou, Satoru Yamada, Tetsuhiro Kajikawa, Nobuhiro Ozaki, Toshihito Awata, Satoko Yamaba, Shinya Murakami

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 426　No. 4　p. 643-648　2012/10　Research paper (scientific journal)

Immunomodulation of dendritic cells differentiated in the presence of nicotine with lipopolysaccharide from Porphyromonas gingivalis

Manabu Yanagita, Kenta Mori, Ryohei Kobayashi, Yuko Kojima, Mikiko Kubota, Koji Miki, Satoru Yamada, Masahiro Kitamura, Shinya Murakami

EUROPEAN JOURNAL OF ORAL SCIENCES　Vol. 120　No. 5　p. 408-414　2012/10　Research paper (scientific journal)

Adiponectin regulates functions of gingival fibroblasts and periodontal ligament cells.

T Iwayama, M Yanagita, K Mori, K Sawada, M Ozasa, M Kubota, K Miki, Y Kojima, M Takedachi, M Kitamura, Y Shimabukuro, T Hashikawa, S Murakami

Journal of periodontal research　Vol. 47　No. 5　p. 563-71　2012/10

CD73-generated adenosine promotes osteoblast differentiation

Masahide Takedachi, Hiroyuki Oohara, Brenda J. Smith, Mitsuyoshi Iyama, Mariko Kobashi, Kenichiro Maeda, Courtney L. Long, Mary B. Humphrey, Barbara J. Stoecker, Satoru Toyosawa, Linda F. Thompson, Shinya Murakami

JOURNAL OF CELLULAR PHYSIOLOGY　Vol. 227　No. 6　p. 2622-2631　2012/06　Research paper (scientific journal)

Nicotine up-regulates IL-8 expression in human gingival epithelial cells following stimulation with IL-1 beta or P. gingivalis lipopolysaccharide via nicotinic acetylcholine receptor signalling

Yoichiro Kashiwagi, Manabu Yanagita, Yuko Kojima, Yoshio Shimabukuro, Shinya Murakami

ARCHIVES OF ORAL BIOLOGY　Vol. 57　No. 5　p. 483-490　2012/05　Research paper (scientific journal)

Effects of L-ascorbic acid 2-phosphate magnesium salt on the properties of human gingival fibroblasts

K. Tsutsumi, H. Fujikawa, T. Kajikawa, M. Takedachi, T. Yamamoto, S. Murakami

JOURNAL OF PERIODONTAL RESEARCH　Vol. 47　No. 2　p. 263-271　2012/04　Research paper (scientific journal)

Nicotine modulates the immunological function of dendritic cells through peroxisome proliferator-activated receptor-gamma upregulation

Manabu Yanagita, Ryohei Kobayashi, Yuko Kojima, Kenta Mori, Shinya Murakami

CELLULAR IMMUNOLOGY　Vol. 274　No. 1-2　p. 26-33　2012/02　Research paper (scientific journal)

[Present status of periodontal regeneration - FGF-2 and Teriparatide - ].

Takedachi M, Murakami S

Clinical calcium　Vol. 22　No. 1　p. 99-104　2012/01

Periodontal disease in a patient with Prader-Willi syndrome: A case report

Manabu Yanagita, Hiroyuki Hirano, Mariko Kobashi, Takenori Nozaki, Satoru Yamada, Masahiro Kitamura, Shinya Murakami

Journal of Medical Case Reports　Vol. 5　2011/07　Research paper (scientific journal)

Periodontal tissue regeneration by signaling molecule(s): what role does basic fibroblast growth factor (FGF-2) have in periodontal therapy?

Shinya Murakami

PERIODONTOLOGY 2000　Vol. 56　No. 1　p. 188-208　2011/06

Fibroblast Growth Factor‐2 Stimulates Periodontal Tissue Regeneration

Shinya Murakami, Satoru Yamada, Takenori Nozaki, Masahiro Kitamura

Clinical Advances in Periodontics　Vol. 1　No. 2　p. 95-99　2011/04　Research paper (scientific journal)

Fibroblast growth factor-2 stimulates directed migration of periodontal ligament cells via PI3K/AKT signaling and CD44/hyaluronan interaction.

Yoshio Shimabukuro, Hiroaki Terashima, Masahide Takedachi, Kenichiro Maeda, Tomomi Nakamura, Keigo Sawada, Mariko Kobashi, Toshihito Awata, Hiroyuki Oohara, Takanobu Kawahara, Tomoaki Iwayama, Tomoko Hashikawa, Manabu Yanagita, Satoru Yamada, Shinya Murakami

Journal of cellular physiology　Vol. 226　No. 3　p. 809-21　2011/03

Development of a multi-layered virtual tooth model for the haptic dental training system

Yoshinori Yoshida, Satoshi Yamaguchi, Yusuke Kawamoto, Hiroshi Noborio, Shinya Murakami, Taiji Sohmura

DENTAL MATERIALS JOURNAL　Vol. 30　No. 1　p. 1-6　2011/01　Research paper (scientific journal)

Osteoinductive and anti-inflammatory effect of royal jelly on periodontal ligament cells

Yanagita Manabu, Kojima Yuko, Mori Kenta, Yamada Satoru, Murakami Shinya

Biomedical research (Tokyo, Japan)　Vol. 32　No. 4　2011

FGF-2 Stimulates Periodontal Regeneration: Results of a Multi-center Randomized Clinical Trial

M. Kitamura, M. Akamatsu, M. Machigashira, Y. Hara, R. Sakagami, T. Hirofuji, T. Hamachi, K. Maeda, M. Yokota, J. Kido, T. Nagata, H. Kurihara, S. Takashiba, T. Sibutani, M. Fukuda, T. Noguchi, K. Yamazaki, H. Yoshie, K. Ioroi, T. Arai, T. Nakagawa, K. Ito, S. Oda, Y. Izumi, Y. Ogata, S. Yamada, H. Shimauchi, K. Kunimatsu, M. Kawanami, T. Fujii, Y. Furuichi, T. Furuuchi, T. Sasano, E. Imai, M. Omae, S. Yamada, M. Watanuki, S. Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 90　No. 1　p. 35-40　2011/01　Research paper (scientific journal)

Effects of concomitant use of fibroblast growth factor (FGF)-2 with beta-tricalcium phosphate (beta-TCP) on the beagle dog 1-wall periodontal defect model

Jun Anzai, Masahiro Kitamura, Takenori Nozaki, Toshie Nagayasu, Akio Terashima, Taiji Asano, Shinya Murakami

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 403　No. 3-4　p. 345-350　2010/12　Research paper (scientific journal)

Suppressive effects of nicotine on the cytodifferentiation of murine periodontal ligament cells

M. Yanagita, Y. Kojima, T. Kawahara, T. Kajikawa, H. Oohara, M. Takedachi, S. Yamada, S. Murakami

ORAL DISEASES　Vol. 16　No. 8　p. 812-817　2010/11　Research paper (scientific journal)

口腔疾患と全身とのかかわり

北村正博, 村上伸也

ファルマシア　Vol. 46　No. 10　p. 923-927　2010/10　Research paper (scientific journal)

Role of Mechanical Stress-induced Glutamate Signaling-associated Molecules in Cytodifferentiation of Periodontal Ligament Cells

Chiharu Fujihara, Satoru Yamada, Nobuhiro Ozaki, Nobuo Takeshita, Harumi Kawaki, Teruko Takano-Yamamoto, Shinya Murakami

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 285　No. 36　p. 28286-28297　2010/09　Research paper (scientific journal)

Reduction of N-glycolylneuraminic acid xenoantigen on human adipose tissue-derived stromal cells/mesenchymal stem cells leads to safer and more useful cell sources for various stem cell therapies.

Hiroshi Komoda, Hanayuki Okura, Chun Man Lee, Nagako Sougawa, Tomoaki Iwayama, Tomoko Hashikawa, Ayami Saga, Aya Yamamoto-Kakuta, Akihiro Ichinose, Shinya Murakami, Yoshiki Sawa, Akifumi Matsuyama

Tissue engineering. Part A　Vol. 16　No. 4　p. 1143-55　2010/04

Genetic Risk Factors for Periodontitis in a Japanese Population

T. Kobayashi, T. Nagata, S. Murakami, S. Takashiba, H. Kurihara, Y. Izumi, Y. Numabe, H. Watanabe, M. Kataoka, A. Nagai, J. Hayashi, H. Ohyama, Y. Okamatsu, Y. Inagaki, H. Tai, H. Yoshie

JOURNAL OF DENTAL RESEARCH　Vol. 88　No. 12　p. 1137-1141　2009/12　Research paper (scientific journal)

Fibroblast Growth Factor-2 Regulates the Cell Function of Human Dental Pulp Cells

Yoshio Shimabukuro, Maki Ueda, Masao Ozasa, Jun Anzai, Masahide Takedachi, Manabu Tanagita, Masako Ito, Tomoko Hashikawa, Satoru Yamada, Shinya Murakami

JOURNAL OF ENDODONTICS　Vol. 35　No. 11　p. 1529-1535　2009/11　Research paper (scientific journal)

Nicotine can skew the characterization of the macrophage type-1 (M Phi 1) phenotype differentiated with granulocyte-macrophage colony-stimulating factor to the M Phi 2 phenotype

Manabu Yanagita, Ryohei Kobayashi, Shinya Murakami

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 388　No. 1　p. 91-95　2009/10　Research paper (scientific journal)

PLAP-1: A novel molecule regulating homeostasis of periodontal tissues

Satoru Yamada, Masahiro Kitamura, Shinya Murakami

Japanese Dental Science Review　Vol. 44　No. 2　p. 137-144　2008/10　Research paper (scientific journal)

ヒト歯根膜細胞の全遺伝子発現プロファイリング解析により同定されたId1の機能解析

山田 聡, 米田 晋也, 藤原 千春, 田内 拓史, 梶川 哲宏, 柳田 学, 北村 正博, 村上 伸也

日本歯周病学会会誌　Vol. 50　No. 秋季特別　p. 106-106　2008/09

Nicotine inhibits mineralization of human dental pulp cells

Manabu Yanagita, Yoichiro Kashiwagi, Ryohei Kobayashi, Miki Tomoeda, Yoshio Shimabukuro, Shinya Murakami

JOURNAL OF ENDODONTICS　Vol. 34　No. 9　p. 1061-1065　2008/09　Research paper (scientific journal)

Fibroblast growth factor-2 regulates expression of osteopontin in periodontal ligament cells

Yoshimitsu Terashima, Yoshio Shimabukuro, Hiroaki Terashima, Masao Ozasa, Mami Terakura, Kazuhiko Ikezawa, Tomoko Hashikawa, Masahide Takedachi, Hiroyuki Oohara, Satoru Yamada, Shinya Murakami

JOURNAL OF CELLULAR PHYSIOLOGY　Vol. 216　No. 3　p. 640-650　2008/09　Research paper (scientific journal)

Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2: Randomized Controlled Phase II Clinical Trial

Masahiro Kitamura, Keisuke Nakashima, Yusuke Kowashi, Takeo Fujii, Hidetoshi Shimauchi, Takashi Sasano, Toshi Furuuchi, Mitsuo Fukuda, Toshihide Noguchi, Toshiaki Shibutani, Yukio Iwayama, Shogo Takashiba, Hidemi Kurihara, Masami Ninomiya, Jun-ichi Kido, Toshihiko Nagata, Takafumi Hamachi, Katsumasa Maeda, Yoshitaka Hara, Yuichi Izumi, Takao Hirofuji, Enyu Imai, Masatoshi Omae, Mitsuru Watanuki, Shinya Murakami

PLOS ONE　Vol. 3　No. 7　2008/07　Research paper (scientific journal)

PLAP-1/asporin inhibits activation of BMP receptor via its leucine-rich repeat motif

M. Tomoeda, S. Yamada, H. Shirai, Y. Ozawa, M. Yanagita, S. Murakami

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 371　No. 2　p. 191-196　2008/06　Research paper (scientific journal)

CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes

Masahide Takedachi, Dongfeng Qu, Yukihiko Ebisuno, Hiroyuki Oohara, Michelle L. Joachims, Stephanie T. McGee, Emiko Maeda, Rodger P. McEver, Toshiyuki Tanaka, Masayuki Miyasaka, Shinya Murakami, Thomas Krahn, Michael R. Blackburn, Linda F. Thompson

JOURNAL OF IMMUNOLOGY　Vol. 180　No. 9　p. 6288-6296　2008/05　Research paper (scientific journal)

KCB-1D(FGF-2)歯周組織再生試験(後期第II相)(その1) 有効性の評価

北村 正博, 古市 保志, 藤井 健男, 川浪 雅光, 國松 和司, 島内 英俊, 笹野 高嗣, 山田 了, 小方 頼昌, 小田 茂, 和泉 雄一, 伊藤 公一, 中川 種昭, 新井 高, 吉江 弘正, 山崎 和久, 福田 光男, 野口 俊英, 渋谷 俊昭, 高柴 正悟, 栗原 英見, 永田 俊彦, 横田 誠, 濱地 貴文, 前田 勝正, 廣藤 卓雄, 坂上 竜資, 原 宜興, 町頭 三保, 五百蔵 一男, 山田 聡, 村上 伸也

日本歯周病学会会誌　Vol. 50　No. 春季特別　p. 169-169　2008/04

KCB-1D(FGF-2)歯周組織再生試験(後期第II相)(その2) 安全性の評価

山田 聡, 古市 保志, 藤井 健男, 川浪 雅光, 國松 和司, 島内 英俊, 山田 了, 小方 頼昌, 小田 茂, 和泉 雄一, 伊藤 公一, 中川 種昭, 新井 高, 吉江 弘正, 山崎 和久, 福田 光男, 野口 俊英, 渋谷 俊昭, 高柴 正悟, 栗原 英見, 永田 俊彦, 横田 誠, 濱地 貴文, 前田 勝正, 廣藤 卓雄, 坂上 竜資, 原 宜興, 町頭 三保, 五百蔵 一男, 北村 正博, 村上 伸也

日本歯周病学会会誌　Vol. 50　No. 春季特別　p. 170-170　2008/04

Basic fibroblast growth factor regulates expression of heparan sulfate in human periodontal ligament cells

Shimabukuro Yoshio, Ichikawa Tomoo, Terashima Yoshimitsu, Iwayama Tomoaki, Oohara Hiroyuki, Kajikawa Tetsuhiro, Kobayashi Ryohei, Terashima Hiroaki, Takedachi Masahide, Terakura Mami, Hashikawa Tomoko, Yamada Satoru, Murakami Shinya

Matrix biology : journal of the International Society for Matrix Biology　Vol. 27　No. 3　2008

Thrombin regulates the function of human blood dendritic cells

Manabu Yanagita, Ryohei Kobayashi, Yoichiro Kashiwagi, Yoshio Shimabukuro, Shinya Murakami

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 364　No. 2　p. 318-324　2007/12　Research paper (scientific journal)

メカニカルストレスがヒト歯根膜細胞に及ぼす影響の網羅的遺伝子発現解析

藤原 千春, 山田 聡, 米田 晋也, 田内 拓史, 梶川 哲宏, 小澤 康宏, 村上 伸也

日本歯周病学会会誌　Vol. 49　No. 秋季特別　p. 202-202　2007/08

PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization

Satoru Yamada, Miki Tomoeda, Yasuhiro Ozawa, Shinya Yoneda, Yoshimitsu Terashima, Kazuhiko Ikezawa, Shiro Ikegawa, Masahiro Saito, Satoru Toyosawa, Shinya Murakami

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 282　No. 32　p. 23070-23080　2007/08　Research paper (scientific journal)

培養ヒト歯根膜細胞中に存在するSide Population細胞の特徴

小出 容子, 小林 誠, 奥津 朋彦, 三井 将, 松崎 有未, 山田 聡, 村上 伸也, 山本 松男

日本歯周病学会会誌　Vol. 48　No. 秋季特別　p. 111-111　2006/09

Regulation of PLAP-1 expression in periodontal ligament cells

S Yamada, Y Ozawa, M Tomoeda, R Matoba, K Matsubara, S Murakami

JOURNAL OF DENTAL RESEARCH　Vol. 85　No. 5　p. 447-451　2006/05　Research paper (scientific journal)

Activation of adenosine receptor on gingival fibroblasts

Hashikawa T, Takedachi M, Terakura M, Yamada S, Thompson L. F, Shimabukuro Y, Murakami S

Journal of dental research　Vol. 85　No. 8　2006

若年者における歯周病発症の臨床的及び細菌学的検討

野崎剛徳, 森谷洋介, 山崎彰久, 北村正博, 奥田耕三, 中平 陽, 寺倉まみ, 市川朋生, 伊藤正子, 島袋善夫, 村上伸也

日歯保存誌　2005/09　Research paper (scientific journal)

Expression level of valosin-containing protein (VCP) as a prognostic marker for gingival squamous cell carcinoma

S Yamamoto, Y Tomita, Y Hoshida, S Toyosawa, H Inohara, M Kishino, M Kogo, M Nakazawa, S Murakami, N Iizuka, S Kidogami, M Monden, T Kubo, N Ijuhin, K Aozasa

ANNALS OF ONCOLOGY　Vol. 15　No. 9　p. 1432-1438　2004/09　Research paper (scientific journal)

Human gingival epithelial cells produce chemotactic factors interleukin-8 and monocyte chemoattractant protein-1 after stimulation with Porphyromonas gingivalis via toll-like receptor 2

Kusumoto Yutaka, Hirano Hiroyuki, Saitoh Keiko, Yamada Satoru, Takedachi Masahide, Nozaki Takenori, Ozawa Yasuhiro, Nakahira You, Saho Teruyuki, Ogo Hideji, Shimabukuro Yoshio, Okada Hiroshi, Murakami Shinya

Journal of periodontology　Vol. 75　No. 3　2004

Recombinant human basic fibroblast growth factor (bFGF) stimulates periodontal regeneration in class II furcation defects created in beagle dogs

Murakami S, Takayama S, Kitamura M, Shimabukuro Y, Yanagi K, Ikezawa K, Saho T, Nozaki T, Okada H

Journal of periodontal research　Vol. 38　No. 1　2003

Involvement of CD73 (ecto-5'-nucleotidase) in adenosine generation by human gingival fibroblasts

Hashikawa T, Takedachi M, Terakura M, Saho T, Yamada S, Thompson L. F, Shimabukuro Y, Murakami S

Journal of dental research　Vol. 82　No. 11　2003

Induction of CD13 on T-lymphocytes by adhesive interaction with gingival fibroblasts

Saho T, Kishida T, Hirano H, Hashikawa T, Shimabukuro Y, Murakami S

Journal of dental research　Vol. 82　No. 11　2003

IL-15 up-regulates iNOS expression and NO production by gingival epithelial cells

Yanagita Manabu, Shimabukuro Yoshio, Nozaki Takenori, Yoshimura Naoko, Watanabe Junko, Koide Hiroko, Terakura Mami, Saho Teruyuki, Takedachi Masahide, Jang Myoung-Ho, Kiyono Hiroshi, Murakami Shinya

Biochemical and biophysical research communications　Vol. 297　No. 2　2002

Activation of adenosine-receptor-enhanced iNOS mRNA expression by gingival epithelial cells

Murakami S, Yoshimura N, Koide H, Watanabe J, Takedachi M, Terakura M, Yanagita M, Hashikawa T, Saho T, Shimabukuro Y, Okada H

Journal of dental research　Vol. 81　No. 4　2002

Periodontal regeneration by FGF-2 (bFGF) in primate models

Takayama S, Murakami S, Shimabukuro Y, Kitamura M, Okada H

Journal of dental research　Vol. 80　No. 12　2001

Expression profile of active genes in human periodontal ligament and isolation of PLAP-1, a novel SLRP family gene

Yamada S, Murakami S, Matoba R, Ozawa Y, Yokokoji T, Nakahira Y, Ikezawa K, Takayama S, Matsubara K, Okada H

Gene　Vol. 275　No. 2　2001

Adenosine regulates the IL-1 beta-induced cellular functions of human gingival fibroblasts

Murakami S, Hashikawa T, Saho T, Takedachi M, Nozaki T, Shimabukuro Y, Okada H

International immunology　Vol. 13　No. 12　2001

Adenosine regulates the production of interleukin-6 by human gingival fibroblasts via cyclic AMP/protein kinase A pathway

Murakami S, Terakura M, Kamatani T, Hashikawa T, Saho T, Shimabukuro Y, Okada H

Journal of periodontal research　Vol. 35　No. 2　2000

Regeneration of periodontal tissues by basic fibroblast growth factor

Murakami S, Takayama S, Ikezawa K, Shimabukuro Y, Kitamura M, Nozaki T, Terashima A, Asano T, Okada H

Journal of periodontal research　Vol. 34　No. 7　1999

Nasopharyngeal-associated lymphoreticular tissue (NALT) immunity: fimbriae-specific Th1 and Th2 cell-regulated IgA responses for the inhibition of bacterial attachment to epithelial cells and subsequent inflammatory cytokine production

Yanagita M, Hiroi T, Kitagaki N, Hamada S, Ito H. O, Shimauchi H, Murakami S, Okada H, Kiyono H

Journal of immunology (Baltimore, Md. : 1950)　Vol. 162　No. 6　1999

Direct interaction between gingival fibroblasts and lymphoid cells induces inflammatory cytokine mRNA expression in gingival fibroblasts

Murakami S, Hino E, Shimabukuro Y, Nozaki T, Kusumoto Y, Saho T, Hirano F, Hirano H, Okada H

Journal of dental research　Vol. 78　No. 1　1999

Expression of receptors for basic fibroblast growth factor on human periodontal ligament cells

Takayama S, Murakami S, Nozaki T, Ikezawa K, Miki Y, Asano T, Terashima A, Okada H

Journal of periodontal research　Vol. 33　No. 6　1998

Cytokine expression in periodontal health and disease

Okada H, Murakami S

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists　Vol. 9　No. 3　1998

Lymphocyte-fibroblast interactions

Murakami S, Okada H

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists　Vol. 8　No. 1　1997

Immunoregulatory roles of adhesive interactions between lymphocytes and gingival fibroblasts

S Murakami, Y Shimabukuro, T Saho, E Hino, D Kasai, T Hashikawa, H Hirano, H Okada

JOURNAL OF PERIODONTAL RESEARCH　Vol. 32　No. 1　p. 110-114　1997/01　Research paper (scientific journal)

Effects of basic fibroblast growth factor on human periodontal ligament cells

Takayama S, Murakami S, Miki Y, Ikezawa K, Tasaka S, Terashima A, Asano T, Okada H

Journal of periodontal research　Vol. 32　No. 8　1997

CD44 isoform expression in periodontal tissues: cell-type specific regulation of alternative splicing

Hirano F, Hirano H, Hino E, Takayama S, Saito K, Kusumoto Y, Shimabukuro Y, Murakami S, Okada H

Journal of periodontal research　Vol. 32　No. 8　1997

Development of Controlled Release Preparation Containing Sparfloxacin(PT-02)for Topical Chemotherapy of Periodontal Disease-Climical and Microbiological Eraluation after Topical Application of PT-02 into Periodontal Pockets-

KITAMURA Masahiro

1996/12　Research paper (scientific journal)

CD44-hyaluronate interaction participates in the adherence of T-lymphocytes to gingival fibroblasts

Murakami S, Saho T, Asari A, Hino E, Kasai D, Shimabukuro Y, Okada H

Journal of dental research　Vol. 75　No. 8　1996

Antigen-presenting-cell function of interferon gamma-treated human gingival fibroblasts

Shimabukuro Y, Murakami S, Okada H

Journal of periodontal research　Vol. 31　No. 3　1996

Inducible binding of human lymphocytes to hyaluronate via CD44 does not require cytoskeleton association but does require new protein synthesis

Murakami S, Shimabukuro Y, Miki Y, Saho T, Hino E, Kasai D, Nozaki T, Kusumoto Y, Okada H

Journal of immunology (Baltimore, Md. : 1950)　Vol. 152　No. 2　1994

EVIDENCE FOR A ROLE OF VLA INTEGRINS IN LYMPHOCYTE-HUMAN GINGIVAL FIBROBLAST ADHERENCE

S MURAKAMI, Y SHIMABUKURO, T SAHO, R ISODA, K KAMEYAMA, K YAMASHITA, H OKADA

JOURNAL OF PERIODONTAL RESEARCH　Vol. 28　No. 6　p. 494-496　1993/11　Research paper (scientific journal)

Interferon-gamma-dependent immunosuppressive effects of human gingival fibroblasts

Shimabukuro Y, Murakami S, Okada H

Immunology　Vol. 76　No. 2　1992

Characterization of autoantibody-secreting B cells in mice undergoing stimulatory (chronic) graft-versus-host reactions. Identification of a CD44hi population that binds specifically to hyaluronate

Murakami S, Miyake K, Abe R, Kincade P. W, Hodes R. J

Journal of immunology (Baltimore, Md. : 1950)　Vol. 146　No. 5　1991

IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate

Murakami S, Miyake K, June C. H, Kincade P. W, Hodes R. J

Journal of immunology (Baltimore, Md. : 1950)　Vol. 145　No. 11　1990

T-cell-derived factor B151-TRF1/IL-5 activates blastoid cells among unprimed B cells to induce a polyclonal differentiation into immunoglobulin M-secreting cells

Murakami S, Ono S, Harada N, Hara Y, Katoh Y, Dobashi K, Takatsu K, Hamaoka T

Immunology　Vol. 65　No. 2　1988