HOXA10 promotes Gdf5 expression in articular chondrocytes.

Tomohiko Murakami, Lerdluck Ruengsinpinya, Yoshifumi Takahata, Yuri Nakaminami, Kenji Hata, Riko Nishimura

Scientific reports　Vol. 13　No. 1　p. 22778-22778　2023/12/20　Research paper (scientific journal)

The acid-sensing nociceptor TRPV1 controls breast cancer progression in bone via regulating HGF secretion from sensory neurons.

Tatsuo Okui, Masahiro Hiasa, Kenji Hata, G David Roodman, Masako Nakanishi, Toshiyuki Yoneda

Research square　2023/07/05

Fam20C overexpression in odontoblasts regulates dentin formation and odontoblast differentiation.

Kohei Naniwa, Katsutoshi Hirose, Yu Usami, Kenji Hata, Rikita Araki, Narikazu Uzawa, Toshihisa Komori, Satoru Toyosawa

Journal of Molecular Histology　2023/06　Research paper (scientific journal)

Cancer-nerve interplay in cancer progression and cancer-induced bone pain.

Toshiyuki Yoneda, Masahiro Hiasa, Tatsuo Okui, Kenji Hata

Journal of bone and mineral metabolism　Vol. 41　No. 3　p. 415-427　2023/05　Research paper (scientific journal)

The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer

Shota Ishihara, Kenji Hata, Katsutoshi Hirose, Tatsuo Okui, Satoru Toyosawa, Narikazu Uzawa, Riko Nishimura, Toshiyuki Yoneda

Scientific Reports　Vol. 12　No. 1　2022/12　Research paper (scientific journal)

Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes.

Tomohiko Murakami, Yoshifumi Takahata, Kenji Hata, Kosuke Ebina, Katsutoshi Hirose, Lerdluck Ruengsinpinya, Yuri Nakaminami, Yuki Etani, Sachi Kobayashi, Takashi Maruyama, Hiroyasu Nakano, Takehito Kaneko, Satoru Toyosawa, Hiroshi Asahara, Riko Nishimura

Science signaling　Vol. 15　No. 758　2022/11　Research paper (scientific journal)

Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx2.

Hiroko Yagi, Yoshifumi Takahata, Tomohiko Murakami, Yuri Nakaminami, Hiromasa Hagino, Shiori Yamamoto, Shinya Murakami, Kenji Hata, Riko Nishimura

Journal of bone and mineral metabolism　2022/06/28　Research paper (scientific journal)

Activation and Function of NLRP3 Inflammasome in Bone and Joint-Related Diseases.

Tomohiko Murakami, Yuri Nakaminami, Yoshifumi Takahata, Kenji Hata, Riko Nishimura

International journal of molecular sciences　Vol. 23　No. 10　2022/05/11　Research paper (scientific journal)

Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis

Yoshifumi Takahata, Hiromasa Hagino, Ayaka Kimura, Mitsuki Urushizaki, Shiori Yamamoto, Kanta Wakamori, Tomohiko Murakami, Kenji Hata, Riko Nishimura

International Journal of Molecular Sciences　Vol. 23　No. 9　p. 4672-4672　2022/04/23　Research paper (scientific journal)

PIK3CA mutation correlates with mTOR pathway expression but not clinical and pathological features in Fibfibroipose vascular anomaly (FAVA).

Yumiko Hori, Katsutoshi Hirose, Michio Ozeki, Kenji Hata, Daisuke Motooka, Shinichiro Tahara, Takahiro Matsui, Masaharu Kohara, Hiroki Higashihara, Yusuke Ono, Kaishu Tanaka, Satoru Toyosawa, Eiichi Morii

Diagnostic pathology　Vol. 17　No. 1　p. 19-19　2022/01/30　Research paper (scientific journal)

Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice

Eriko Nakamura, Kenji Hata, Yoshifumi Takahata, Hiroshi Kurosaka, Makoto Abe, Takaya Abe, Miho Kihara, Toshihisa Komori, Sachi Kobayashi, Tomohiko Murakami, Toshihiro Inubushi, Takashi Yamashiro, Shiori Yamamoto, Haruhiko Akiyama, Makoto Kawaguchi, Nobuo Sakata, Riko Nishimura

Communications Biology　Vol. 4　No. 1　2021/12　Research paper (scientific journal)

Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2

Yoshifumi Takahata, Hiromasa Hagino, Ayaka Kimura, Mitsuki Urushizaki, Sachi Kobayashi, Kanta Wakamori, Chika Fujiwara, Eriko Nakamura, Kayon Yu, Hiroshi Kiyonari, Kana Bando, Tomohiko Murakami, Toshihisa Komori, Kenji Hata, Riko Nishimura

Communications Biology　Vol. 4　No. 1　2021/12　Research paper (scientific journal)

Induction of salivary gland-like cells from epithelial tissues transdifferentiated from mouse embryonic fibroblasts.

Ryogo Katada, Junichi Tanaka, Koki Takamatsu, Kenji Hata, Rika Yasuhara, Shintaro Ohnuma, Ikuko Takakura, Riko Nishimura, Tatsuo Shirota, Kenji Mishima

Biochemical and biophysical research communications　Vol. 586　p. 55-62　2021/11/19　Research paper (scientific journal)

Sensory nerves: A driver of the vicious cycle in bone metastasis?

Toshiyuki Yoneda, Masahiro Hiasa, Tatsuo Okui, Kenji Hata

Journal of Bone Oncology　Vol. 30　p. 100387-100387　2021/10　Research paper (scientific journal)

Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2

Koichiro Ono, Kenji Hata, Eriko Nakamura, Shota Ishihara, Sachi Kobayashi, Masako Nakanishi, Michiko Yoshida, Yoshifumi Takahata, Tomohiko Murakami, Seiichi Takenoshita, Toshihisa Komori, Riko Nishimura, Toshiyuki Yoneda

Communications Biology　Vol. 4　No. 1　p. 326-326　2021/03　Research paper (scientific journal)

G protein subunit β1 is an important mediator of the late stage of endochondral ossification

Lerdluck Ruengsinpinya, Tomohiko Murakami, Eriko Nakamura, Yoshifumi Takahata, Kenji Hata, Yuri Nakaminami, Hiroaki Okae, Riko Nishimura

Biochemical and Biophysical Research Communications　Vol. 533　No. 1　p. 90-96　2020/11　Research paper (scientific journal)

Role of interleukin-1 and inflammasomes in oral disease.

Tomohiko Murakami, Yoshifumi Takahata, Kenji Hata, Riko Nishimura

Journal of oral biosciences　2020/08/06　Research paper (scientific journal)

成長軟骨板の分子生物学

波多賢二

臨床スポーツ医学　Vol. 37　No. 5　p. 502-507　2020/05　Research paper (scientific journal)

Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis.

Yoshifumi Takahata, Tomohiko Murakami, Kenji Hata, Riko Nishimura

Current molecular pharmacology　2020/04/17　Research paper (scientific journal)

Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases.

Riko Nishimura, Kenji Hata, Yoshifumi Takahata, Tomohiko Murakami, Eriko Nakamura, Maki Ohkawa, Lerdluck Ruengsinpinya

International journal of molecular sciences　Vol. 21　No. 4　2020/02/17　Research paper (scientific journal)

Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.

Junichi Tanaka, Yo Mabuchi, Kenji Hata, Rika Yasuhara, Koki Takamatsu, Satoko Kujiraoka, Akane Yukimori, Ikuko Takakura, Hidetoshi Sumimoto, Toshiyuki Fukada, Masayuki Azuma, Haruhiko Akiyama, Riko Nishimura, Toshikazu Shimane, Kenji Mishima

Experimental cell research　Vol. 382　No. 1　p. 111449-111449　2019/09/01　Research paper (scientific journal)

Cutting Edge: G Protein Subunit β 1 Negatively Regulates NLRP3 Inflammasome Activation

Tomohiko Murakami, Lerdluck Ruengsinpinya, Eriko Nakamura, Yoshifumi Takahata, Kenji Hata, Hiroaki Okae, Shun’ichiro Taniguchi, Masafumi Takahashi, Riko Nishimura

The Journal of Immunology　Vol. 202　No. 7　p. 1942-1947　2019/04　Research paper (scientific journal)

Generation of orthotopically functional salivary gland from embryonic stem cells.

Junichi Tanaka, Miho Ogawa, Hironori Hojo, Yusuke Kawashima, Yo Mabuchi, Kenji Hata, Shiro Nakamura, Rika Yasuhara, Koki Takamatsu, Tarou Irié, Toshiyuki Fukada, Takayoshi Sakai, Tomio Inoue, Riko Nishimura, Osamu Ohara, Ichiro Saito, Shinsuke Ohba, Takashi Tsuji, Kenji Mishima

Nature communications　Vol. 9　No. 1　p. 4216-4216　2018/10/11　Research paper (scientific journal)

Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a.

Kida J, Hata K, Nakamura E, Yagi H, Takahata Y, Murakami T, Maeda Y, Nishimura R

Sci Rep.　2018/07　Research paper (scientific journal)

Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.

Takahata Y, Nakamura E, Hata K, Wakabayashi M, Murakami T, Wakamori K, Yoshikawa H, Matsuda A, Fukui N, Nishimura R

FASEB J.　2018/07　Research paper (scientific journal)

Decreased sensory nerve excitation and bone pain associated with mouse Lewis lung cancer in TRPV1-deficient mice

Hiroki Wakabayashi, Satoshi Wakisaka, Toru Hiraga, Kenji Hata, Riko Nishimura, Makoto Tominaga, Toshiyuki Yoneda

Journal of Bone and Mineral Metabolism　Vol. 36　No. 3　p. 274-285　2018/05/01　Research paper (scientific journal)

Transcriptional network systems in cartilage development and disease

Riko Nishimura, Kenji Hata, Eriko Nakamura, Tomohiko Murakami, Yoshifumi Takahata

Histochemistry and Cell Biology　Vol. 149　No. 4　p. 353-363　2018/04/01

[Homeostasis and Disorder of Musculoskeletal System.Mechanisms of cartilage development and homeostasis.]

Nishimura R, Hata K, Nakamura E

Clinical calcium　Vol. 28　No. 3　p. 353-359　2018

Regulation of Cartilage Development and Diseases by Transcription Factors.

Nishimura R, Hata K, Takahata Y, Murakami T, Nakamura E, Yagi H

Journal of bone metabolism　Vol. 24　No. 3　p. 147-153　2017/08　Research paper (scientific journal)

Transcriptional Network Controlling Endochondral Ossification

Hata, K, Takahata, Y, Murakami, T, Nishimura, R

J Bone Metab　2017/05

Acidic microenvironments induce lymphangiogenesis and IL-8 production via TRPV1 activation in human lymphatic endothelial cells

Masako Nakanishi, Yoshihiro Morita, Kenji Hata, Yasuteru Muragaki

EXPERIMENTAL CELL RESEARCH　Vol. 345　No. 2　p. 180-189　2016/07　Research paper (scientific journal)

Epigenetic regulation of chondrocyte differentiation

Kenji Hata

Japanese Dental Science Review　Vol. 51　No. 4　p. 105-113　2015/11/01

Cellular fibronectin 1 promotes VEGF-C expression, lymphangiogenesis and lymph node metastasis associated with human oral squamous cell carcinoma

Yoshihiro Morita, Kenji Hata, Masako Nakanishi, Tetsuji Omata, Nobuo Morita, Yoshiaki Yura, Riko Nishimura, Toshiyuki Yoneda

CLINICAL & EXPERIMENTAL METASTASIS　Vol. 32　No. 7　p. 739-753　2015/10　Research paper (scientific journal)

The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification

Michiko Yoshida, Kenji Hata, Rikako Takashima, Koichiro Ono, Eriko Nakamura, Yoshifumi Takahata, Tomohiko Murakami, Sachiko Iseki, Teruko Takano-Yamamoto, Riko Nishimura, Toshiyuki Yoneda

NATURE COMMUNICATIONS　Vol. 6　2015/03　Research paper (scientific journal)

Regulation of transcriptional network system during bone and cartilage development

Riko Nishimura, Kenji Hata, Fumiyo Ikeda, Takuma Matsubara, Katsuhiko Amano, Koichiro Ono, Yoko Takigawa, Rikako Takashima, Michiko Yoshida, Eriko Nakamura, Toshiyuki Yoneda

Journal of Oral Biosciences　Vol. 57　No. 4　p. 165-170　2015

[Bone and Stem Cells. Regulation of chondrocyte differentiation from mesenchymal stem cells].

Nishimura R, Nakamura E, Kida J, Yagi H, Hata K

Clinical calcium　Vol. 24　No. 4　p. 509-516　2014/04

Cyclooxygenase-2 expression is associated with vascular endothelial growth factor-c and lymph node metastasis in human oral tongue cancer

Yoshihiro Morita, Nobuo Morita, Kenji Hata, Masako Nakanishi, Natsuko Kimoto, Tetsuji Omata, Yasushi Nakamura, Toshiyuki Yoneda

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY　Vol. 117　No. 4　p. 502-510　2014/04　Research paper (scientific journal)

Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes

Kenji Hata, Rikako Takashima, Katsuhiko Amano, Koichiro Ono, Masako Nakanishi, Michiko Yoshida, Makoto Wakabayashi, Akio Matsuda, Yoshinobu Maeda, Yutaka Suzuki, Sumio Sugano, Robert H. Whitson, Riko Nishimura, Toshiyuki Yoneda

Nature Communications　Vol. 4　2013/11/26　Research paper (scientific journal)

[Modulation of transcriptional regulation during bone and cartilage development and their disease].

Nishimura R, Hata K, Takashima R, Yoshida M, Nakamura E, Kida J, Yagi H

Clinical calcium　Vol. 23　No. 11　p. 1585-1593　2013/11

Role of RANKL/RANK in primary and secondary breast cancer

Toshiyuki Yoneda, Soichi Tanaka, Kenji Hata

World Journal of Orthopaedics　Vol. 4　No. 4　p. 178-185　2013/10/18　Research paper (scientific journal)

【続発性骨粗鬆症-診断と対策-】悪性腫瘍と骨病変 悪性腫瘍の骨転移の分子メカニズム

西村 理行, 波多 賢二, 田中 宗一, 森田 祥弘

THE BONE　Vol. 27　No. 2　p. 205-209　2013/05

Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: A model of spondylocostal dysostosis and spondylothoracic dysostosis

Yuji Makino, Yu Takahashi, Rieko Tanabe, Yoshihiro Tamamura, Takashi Watanabe, Mayu Haraikawa, Miwako Hamagaki, Kenji Hata, Jun Kanno, Toshiyuki Yoneda, Yumiko Saga, Masae Goseki-Sone, Kazuo Kaneko, Akira Yamaguchi, Tadahiro Iimura

BONE　Vol. 53　No. 1　p. 248-258　2013/03　Research paper (scientific journal)

Retinoic acid regulates commitment of undifferentiated mesenchymal stem cells into osteoblasts and adipocytes

Kunihiro Hisada, Kenji Hata, Fumitaka Ichida, Takuma Matsubara, Hideo Orimo, Tamaki Nakano, Hirohumi Yatani, Riko Nishimura, Toshiyuki Yoneda

JOURNAL OF BONE AND MINERAL METABOLISM　Vol. 31　No. 1　p. 53-63　2013/01　Research paper (scientific journal)

Cyclooxygenase-2 promotes tumor lymphangiogenesis and lymph node metastasis in oral squamous cell carcinoma

Yoshihiro Morita, Kenji Hata, Masako Nakanishi, Toshihiko Nishisho, Yoshiaki Yura, Toshiyuki Yoneda

International Journal of Oncology　Vol. 41　No. 3　p. 885-892　2012/09　Research paper (scientific journal)

Osterix Regulates Calcification and Degradation of Chondrogenic Matrices through Matrix Metalloproteinase 13 (MMP13) Expression in Association with Transcription Factor Runx2 during Endochondral Ossification

Riko Nishimura, Makoto Wakabayashi, Kenji Hata, Takuma Matsubara, Shiho Honma, Satoshi Wakisaka, Hiroshi Kiyonari, Go Shioi, Akira Yamaguchi, Noriyuki Tsumaki, Haruhiko Akiyama, Toshiyuki Yoneda

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 287　No. 40　p. 33179-33190　2012/09　Research paper (scientific journal)

Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases

Toru Hiraga, Akira Myoui, Nobuyuki Hashimoto, Akira Sasaki, Kenji Hata, Yoshihiro Morita, Hideki Yoshikawa, Clifford J. Rosen, Gregory R. Mundy, Toshiyuki Yoneda

CANCER RESEARCH　Vol. 72　No. 16　p. 4238-4249　2012/08　Research paper (scientific journal)

骨代謝/骨粗鬆症研究の進展 骨髄微小環境とがん細胞

米田 俊之, 田中 宗一, 波多 賢二

日本骨代謝学会学術集会プログラム抄録集　Vol. 30回　p. 103-103　2012/07

骨髄環境は乳がん細胞の上皮間葉転換(Epithelial-Mesenchymal Transition)を促進する

田中 宗一, 波多 賢二, 米田 俊之

日本骨代謝学会学術集会プログラム抄録集　Vol. 30回　p. 215-215　2012/07

[Role and function regulation of transcription factors in endochondral ossification].

Nishimura R, Hata K, Takashima R, Yoshida M

Clinical calcium　Vol. 22　No. 5　p. 643-652　2012/05

Regulation of bone and cartilage development by network between BMP signalling and transcription factors

Riko Nishimura, Kenji Hata, Takuma Matsubara, Makoto Wakabayashi, Toshiyuki Yoneda

Journal of Biochemistry　Vol. 151　No. 3　p. 247-254　2012/03

[Potential use of parathyroid hormone (PTH) in the treatments for oral diseases].

Tanaka S, Hata K, Yoneda T

Clinical calcium　Vol. 22　No. 1　p. 75-82　2012/01

Regulation of endochondral ossification by transcription factors

Riko Nishimura, Kenji Hata, Koichiro Ono, Rikako Takashima, Michiko Yoshida, Toshiyuki Yoneda

Journal of Oral Biosciences　Vol. 54　No. 4　p. 180-183　2012

【口の病気とカルシウム代謝】副甲状腺ホルモン(PTH)の歯科治療への応用の可能性

田中 宗一, 波多 賢二, 米田 俊之

Clinical Calcium　Vol. 22　No. 1　p. 75-82　2011/12

転写因子Arid5bはSox9の転写機能を促進することにより軟骨細胞分化を制御する

高島 利加子, 波多 賢二, 若林 真, 小野 孝一郎, 天野 克比古, 中西 雅子, 前田 芳信, 西村 理行, 米田 俊之

日本骨代謝学会学術集会プログラム抄録集　Vol. 29回　p. 191-191　2011/07

The a3 isoform vacuolar type H +-ATPase promotes distant metastasis in the mouse B16 melanoma cells

Toshihiko Nishisho, Kenji Hata, Masako Nakanishi, Yoshihiro Morita, Ge-Hong Sun-Wada, Yoh Wada, Natsuo Yasui, Toshiyuki Yoneda

Molecular Cancer Research　Vol. 9　No. 7　p. 845-855　2011/07　Research paper (scientific journal)

Regulation of endochondral ossification by transcription factors

Riko Nishimura, Kenji Hata, Koichiro Ono, Katsuhiko Amano, Yoko Takigawa, Makoto Wakabayashi, Rikako Takashima, Toshiyuki Yoneda

Frontiers in Bioscience　Vol. 17　No. 7　p. 2657-2667　2011/06/01　Research paper (scientific journal)

Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription

Katsuhiko Amano, Kenji Hata, Shuji Muramatsu, Makoto Wakabayashi, Yoko Takigawa, Koichiro Ono, Masako Nakanishi, Rikako Takashima, Mikihiko Kogo, Akio Matsuda, Riko Nishimura, Toshiyuki Yoneda

Molecular Biology of the Cell　Vol. 22　No. 8　p. 1300-1311　2011/04/15　Research paper (scientific journal)

[Encounter of cancer cells with bone. The bone microenvironment and cancer metastases].

Kenji Hata, Masako Nakanishi, Yoshihiro Morita, Toshiyuki Yoneda

Clinical calcium　Vol. 21　No. 3　p. 349-56　2011/03　Research paper (scientific journal)

Involvement of acidic microenvironment in the pathophysiology of cancer-associated bone pain

Toshiyuki Yoneda, Kenji Hata, Masako Nakanishi, Maho Nagae, Tomotaka Nagayama, Hiroki Wakabayashi, Toshihiko Nishisho, Teruhisa Sakurai, Toru Hiraga

BONE　Vol. 48　No. 1　p. 100-105　2011/01

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

Yoko Takigawa, Kenji Hata, Shuji Muramatsu, Katsuhiko Amano, Koichiro Ono, Makoto Wakabayashi, Akio Matsuda, Kenji Takada, Riko Nishimura, Toshiyuki Yoneda

Journal of Cell Science　Vol. 123　No. 21　p. 3780-3788　2010/11/01　Research paper (scientific journal)

Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade: A potential mechanism of inflammatory pain

Masako Nakanishi, Kenji Hata, Tomotaka Nagayama, Teruhisa Sakurai, Toshihiko Nishisho, Hiroki Wakabayashi, Toru Hiraga, Shigeyuki Ebisu, Toshiyuki Yoneda

Molecular Biology of the Cell　Vol. 21　No. 15　p. 2568-2577　2010/08/01　Research paper (scientific journal)

Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts

Takuma Matsubara, Fumiyo Ikeda, Kenji Hata, Masako Nakanishi, Masato Okada, Hisataka Yasuda, Riko Nishimura, Toshiyuki Yoneda

Journal of Bone and Mineral Research　Vol. 25　No. 5　p. 1068-1076　2010/05　Research paper (scientific journal)

Sox9の標的転写因子Dmrt2はRunx2を介して内軟骨性骨化の後期分化を制御する

小野 孝一郎, 波多 賢二, 天野 克比古, 中西 雅子, 西村 理行, 米田 俊之

日本骨代謝学会学術集会プログラム抄録集　Vol. 27回　p. 163-163　2009/07

Sox9 family members negatively regulate maturation and calcification of chondrocytes through up-regulation of parathyroid hormone-related protein

Katsuhiko Amano, Kenji Hata, Atsushi Sugita, Yoko Takigawa, Koichiro Ono, Makoto Wakabayashi, Mikihiko Kogo, Riko Nishimura, Toshiyuki Yoneda

Molecular Biology of the Cell　Vol. 20　No. 21　p. 4541-4551　2009　Research paper (scientific journal)

内軟骨性骨形成の分子制御機構

西村 理行, 波多 賢二, 天野 克比古, 滝川 陽子, 小野 孝一郎, 米田 俊之

最新医学　Vol. 63　No. 11　p. 2170-2175　2008/11

Msx2 stimulates chondrocyte maturation by controlling Ihh expression

Katsuhiko Amano, Fumitaka Ichida, Atsushi Sugita, Kenji Hata, Masahiro Wada, Yoko Takigawa, Masako Nakanishi, Mikihiko Kogo, Riko Nishimura, Toshiyuki Yoneda

Journal of Biological Chemistry　Vol. 283　No. 43　p. 29513-29521　2008/10/24　Research paper (scientific journal)

BMP2 regulates osterix through Msx2 and Runx2 during osteoblast differentiation

Takuma Matsubara, Kumiko Kida, Akira Yamaguchi, Kenji Hata, Fumitaka Ichida, Hiroko Meguro, Hiroyuki Aburatani, Riko Nishimura, Toshiyuki Yoneda

Journal of Biological Chemistry　Vol. 283　No. 43　p. 29119-29125　2008/10/24　Research paper (scientific journal)

性分化制御転写因子Dmrt2は内軟骨性骨化を制御する

小野 孝一郎, 波多 賢二, 杉田 淳, 天野 克比古, 滝川 陽子, 中西 雅子, 西村 理行, 米田 俊之

日本骨代謝学会学術集会プログラム抄録集　Vol. 26回　p. 145-145　2008/10

転写制御因子Znf219は、Sox9転写ファクトリーの構成因子として軟骨細胞分化を制御する

滝川 陽子, 波多 賢二, 村松 周治, 天野 克比古, 小野 孝一郎, 若林 真, 松田 昭生, 西村 理行, 米田 俊之

日本骨代謝学会学術集会プログラム抄録集　Vol. 26回　p. 169-169　2008/10

Sox9ファミリーはPTHrPの発現誘導を介し内軟骨性骨形成の後期分化を抑制する

天野 克比古, 波多 賢二, 小野 孝一郎, 古郷 幹彦, 西村 理行, 米田 俊之

日本骨代謝学会学術集会プログラム抄録集　Vol. 26回　p. 169-169　2008/10

Paraspeckle protein p54(nrb) links Sox9-mediated transcription with RNA processing during chondrogenesis in mice

Kenji Hata, Riko Nishimura, Shuji Muramatsu, Akio Matsuda, Takuma Matsubara, Katsuhiko Amano, Fumiyo Ikeda, Vincent R. Harley, Toshiyuki Yoneda

JOURNAL OF CLINICAL INVESTIGATION　Vol. 118　No. 9　p. 3098-3108　2008/09　Research paper (scientific journal)

内軟骨性骨化におけるDmrt2の役割の検討

小野 孝一郎, 波多 賢二, 中村 恵理子, 杉田 淳, 天野 克比古, 滝川 陽子, 中西 雅子, 西村 理行, 竹之下 誠一, 米田 俊之

日本整形外科学会雑誌　Vol. 82　No. 8　p. S1188-S1188　2008/08

JNK/c-Jun signaling mediates an anti-apoptotic effect of RANKL in osteoclasts

Fumiyo Ikeda, Takuma Matsubara, Taro Tsurukai, Kenji Hata, Riko Nishimura, Toshiyuki Yoneda

Journal of Bone and Mineral Research　Vol. 23　No. 6　p. 907-914　2008/06　Research paper (scientific journal)

Signal transduction and transcriptional regulation during mesenchymal cell differentiation

Riko Nishimura, Kenji Hata, Fumiyo Ikeda, Fumitaka Ichida, Atsuko Shimoyama, Takuma Matsubara, Masahiro Wada, Katsuhiko Amano, Toshiyuki Yoneda

Journal of Bone and Mineral Metabolism　Vol. 26　No. 3　p. 203-212　2008

Regulation of osteoclast differentiation and function by phosphate: Potential role of osteoclasts in the skeletal abnormalities in hypophosphaternic conditions

Tetsuyuki Hayashibara, Toru Hiraga, Atsushi Sugita, Liyang Wang, Kenji Hata, Takashi Ooshima, Toshiyuki Yoneda

JOURNAL OF BONE AND MINERAL RESEARCH　Vol. 22　No. 11　p. 1743-1751　2007/11　Research paper (scientific journal)

Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function

Atsuko Shimoyama, Masahiro Wada, Fumiyo Ikeda, Kenji Hata, Takuma Matsubara, Akira Nifuji, Masaki Noda, Katsuhiko Amano, Akira Yamaguchi, Riko Nishimura, Toshiyuki Yoneda

Molecular Biology of the Cell　Vol. 18　No. 7　p. 2411-2418　2007/07　Research paper (scientific journal)

Osteoblast response to titanium regulates transcriptional activity of Runx2 through MAPK pathway

Kenji Hata, Kazunori Ikebe, Masahiro Wada, Takashi Nokubi

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A　Vol. 81A　No. 2　p. 446-452　2007/05　Research paper (scientific journal)

[Relationship between bone metabolism and adipogenesis].

Nishimura R, Hata K, Yoneda T

Clinical calcium　Vol. 17　No. 2　p. 233-240　2007/02

Critical role of cortactin in actin ring formation and osteoclastic bone resorption

Takuma Matsubara, Akira Myoui, Fumiyo Ikeda, Kenji Hata, Hideki Yoshikawa, Riko Nishimura, Toshiyuki Yoneda

Journal of Bone and Mineral Metabolism　Vol. 24　No. 5　p. 368-372　2006/09　Research paper (scientific journal)

Activation of NFAT signal in vivo leads to osteopenia associated with increased osteoclastogenesis and bone-resorbing activity

Fumiyo Ikeda, Riko Nishimura, Takuma Matsubara, Kenji Hata, Sakamuri V. Reddy, Toshiyuki Yoneda

Journal of Immunology　Vol. 177　No. 4　p. 2384-2390　2006/08/15　Research paper (scientific journal)

Preferential inhibition of bone metastases by 5 '-deoxy-5-fluorouridine and capecitabine in the 4T1/luc mouse breast cancer model

T Hiraga, K Hata, F Ikeda, J Kitagaki, K Fujimoto-Ouchi, Y Tanaka, T Yoneda

ONCOLOGY REPORTS　Vol. 14　No. 3　p. 695-699　2005/09　Research paper (scientific journal)

[Roles of PPAR family in bone metabolisms].

Nishimura R, Hata K, Ichida F

Nihon rinsho. Japanese journal of clinical medicine　Vol. 63　No. 4　p. 591-596　2005/04

A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes

K Hata, R Nishimura, M Ueda, F Ikeda, T Matsubara, F Ichida, K Hisada, T Nokubi, A Yamaguchi, T Yoneda

MOLECULAR AND CELLULAR BIOLOGY　Vol. 25　No. 5　p. 1971-1979　2005/03　Research paper (scientific journal)

Reciprocal roles of Msx2 in regulation of osteoblast and adipocyte differentiation

F Ichida, R Nishimura, K Hata, T Matsubara, F Ikeda, K Hisada, H Yatani, Cao, X, T Komori, A Yamaguchi, T Yoneda

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 279　No. 32　p. 34015-34022　2004/08　Research paper (scientific journal)

Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

F Ikeda, R Nishimura, T Matsubara, S Tanaka, J Inoue, SV Reddy, K Hata, K Yamashita, T Hiraga, T Watanabe, T Kukita, K Yoshioka, A Rao, T Yoneda

JOURNAL OF CLINICAL INVESTIGATION　Vol. 114　No. 4　p. 475-484　2004/08　Research paper (scientific journal)

Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer

Toru Hiraga, Akimi Ueda, Daisuke Tamura, Kenji Hata, Fumiyo Ikeda, Paul J. Williams, Toshiyuki Yoneda

International Journal of Cancer　Vol. 106　No. 6　p. 973-979　2003/10/10　Research paper (scientific journal)

Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis

K Hata, R Nishimura, F Ikeda, K Yamashita, T Matsubara, T Nokubi, T Yoneda

MOLECULAR BIOLOGY OF THE CELL　Vol. 14　No. 2　p. 545-555　2003/02　Research paper (scientific journal)

Core-binding factor alpha(1) (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5

R Nishimura, K Hata, SE Harris, F Ikeda, T Yoneda

BONE　Vol. 31　No. 2　p. 303-312　2002/08　Research paper (scientific journal)

自立している高齢者の口腔と全身の健康（第２報）咀嚼と全身疾患との関係

池邉一典, 佐嶌英則, 難波秀和, 小野高裕, 山本 誠, 安井 栄, 喜多誠一, 吉備政仁, 岩瀬勝也, 清水裕子, 沖山誠司, 波多賢二, 由利京子, 上原美華, 山羽 治, 野首孝祠

老年歯科医学　Vol. 14　p. 131-138　2000　Research paper (scientific journal)