Researcher Directory - Osaka University

Hashimoto Hitoshi

橋本　均

Graduate School of Pharmaceutical Sciences　Medical Pharmacy, Professor

Research History

2007 - 2010, 大阪大学薬学研究科, 准教授
2008 - 2009, バンダービルト大学医学センター精神医学, 客員准教授
2001 - 2007, 大阪大学薬学研究科, 助教授
1998 - 2001, 大阪大学薬学研究科, 講師
1991 - 1998, Osaka University, School of Pharmaceutical Sciences
2010 - , 大阪大学薬学研究科教授

Research Areas

Life sciences, Clinical pharmacy
Life sciences, Pharmaceuticals - health and biochemistry
Life sciences, Pharmacology

Papers

Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells., Satoshi Asano,Ami Ono,Kaede Baba,Teru Uehara,Kotaro Sakamoto,Atsuko Hayata-Takano,Takanobu Nakazawa,Souichi Yanamoto,Kotaro Tanimoto,Hitoshi Hashimoto,Yukio Ago, Journal of pharmacological sciences, Vol. 154, No. 3, p. 139-147, 2024/03
(R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice., Rei Yokoyama,Yukio Ago,Hisato Igarashi,Momoko Higuchi,Masato Tanuma,Yuto Shimazaki,Takafumi Kawai,Kaoru Seiriki,Misuzu Hayashida,Shun Yamaguchi,Hirokazu Tanaka,Takanobu Nakazawa,Yasushi Okamura,Kenji Hashimoto,Atsushi Kasai,Hitoshi Hashimoto, Molecular psychiatry, 2024/02/23
Long-lasting anti-despair and anti-anhedonia effects of (S)-norketamine in social isolation-reared mice., Rei Yokoyama,Momoko Higuchi,Wataru Tanabe,Shinji Tsukada,Hisato Igarashi,Kaoru Seiriki,Takanobu Nakazawa,Atsushi Kasai,Yukio Ago,Hitoshi Hashimoto, Journal of pharmacological sciences, Vol. 154, No. 2, p. 72-76, 2024/02
Clozapine Induces Neuronal Activation in the Medial Prefrontal Cortex in a Projection Target-Biased Manner., Yumi Hirato,Kaoru Seiriki,Leo Kojima,Shohei Yamada,Hiroki Rokujo,Tomoya Takemoto,Takanobu Nakazawa,Atsushi Kasai,Hitoshi Hashimoto, Biological & pharmaceutical bulletin, Vol. 47, No. 2, p. 478-485, 2024
Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo, Taro Ichimura,Taishi Kakizuka,Yuki Sato,Keiko Itano,Kaoru Seiriki,Hitoshi Hashimoto,Hiroya Itoga,Shuichi Onami,Takeharu Nagai, Cold Spring Harbor Laboratory, 2023/08/22
Pituitary Adenylate Cyclase-Activating Polypeptide deficient mice show length abnormalities of the axon initial segment, Misaki Iwahashi,Takeshi Yoshimura,Wakana Harigai,Kazuhiro Takuma,Hitoshi Hashimoto,Taiichi Katayama,Atsuko Hayata-Takano, Journal of Pharmacological Sciences, Elsevier BV, 2023/08
Decreased Expression of EP3 Receptor mRNA in the Brain of Mouse Model of Autism Spectrum Disorder., Kusnandar Anggadiredja,Neng Fisheri Kurniati,Atsushi Kasai,Hitoshi Hashimoto, MicroRNA (Shariqah, United Arab Emirates), 2023/04/27
Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway, Satoshi Asano,Ami Ono,Kotaro Sakamoto,Atsuko Hayata-Takano,Takanobu Nakazawa,Kotaro Tanimoto,Hitoshi Hashimoto,Yukio Ago, Peptides, Elsevier BV, Vol. 161, p. 170940-170940, 2023/03
Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience., Yuma Nagai,Yuri Kisaka,Kento Nomura,Naoya Nishitani,Chihiro Andoh,Masashi Koda,Hiroyuki Kawai,Kaoru Seiriki,Kazuki Nagayasu,Atsushi Kasai,Hisashi Shirakawa,Takanobu Nakazawa,Hitoshi Hashimoto,Shuji Kaneko, Cell reports, Vol. 42, No. 3, p. 112149-112149, 2023/02/22
Pre-treatment of oncolytic reovirus improves tumor accumulation and intratumoral distribution of PEG-liposomes., Maho Eguchi,Seiya Hirata,Ikuho Ishigami,Naomi Shuwari,Ryosuke Ono,Masashi Tachibana,Masato Tanuma,Atsushi Kasai,Hitoshi Hashimoto,Ken-Ichi Ogawara,Hiroyuki Mizuguchi,Fuminori Sakurai, Journal of controlled release : official journal of the Controlled Release Society, Vol. 354, p. 35-44, 2023/02
Parabrachial-to-parasubthalamic nucleus pathway mediates fear-induced suppression of feeding in male mice., Takashi Nagashima,Suguru Tohyama,Kaori Mikami,Masashi Nagase,Mieko Morishima,Atsushi Kasai,Hitoshi Hashimoto,Ayako M Watabe, Nature communications, Vol. 13, No. 1, p. 7913-7913, 2022/12/30
Acute social defeat stress activated neurons project to the claustrum and basolateral amygdala., Masato Tanuma,Misaki Niu,Jin Ohkubo,Hiroki Ueno,Yuka Nakai,Yoshihisa Yokoyama,Kaoru Seiriki,Hitoshi Hashimoto,Atsushi Kasai, Molecular brain, Vol. 15, No. 1, p. 100-100, 2022/12/20
Small-molecule non-peptide antagonists of the PACAP receptor attenuate acute restraint stress-induced anxiety-like behaviors in mice., Yusuke Shintani,Atsuko Hayata-Takano,Yui Yamano,Manato Ikuta,Rei Takeshita,Kazuhiro Takuma,Takuya Okada,Naoki Toyooka,Ichiro Takasaki,Atsuro Miyata,Takashi Kurihara,Hitoshi Hashimoto, Biochemical and Biophysical Research Communications, Vol. 631, p. 146-151, 2022/11/26
Molecular basis of astrocyte diversity and morphology across the CNS in health and disease, Fumito Endo,Atsushi Kasai,Joselyn S. Soto,Xinzhu Yu,Zhe Qu,Hitoshi Hashimoto,Viviana Gradinaru,Riki Kawaguchi,Baljit S. Khakh, Science, American Association for the Advancement of Science (AAAS), Vol. 378, No. 6619, 2022/11/04
Roles of the monoaminergic system in the antidepressant effects of ketamine and its metabolites., Yukio Ago,Rei Yokoyama,Satoshi Asano,Hitoshi Hashimoto, Neuropharmacology, p. 109313-109313, 2022/10/31
The Pivotal Role of Neuropeptide Crosstalk from Ventromedial-PACAP to Dorsomedial-Galanin in the Appetite Regulation in the Mouse Hypothalamus., Yuki Kambe,Thanh Trung Nguyen,Toshiharu Yasaka,Thu Thi Nguyen,Yoshimune Sameshima,Kohei Hashiguchi,Norihito Shintani,Hitoshi Hashimoto,Takashi Kurihara,Atsuro Miyata, Molecular neurobiology, Vol. 60, No. 1, p. 171-182, 2022/10/17
Epigenetic and Neuronal Activity Markers Suggest the Recruitment of the Prefrontal Cortex and Hippocampus in the Three-Hit Model of Depression in Male PACAP Heterozygous Mice., Tamás Gaszner,József Farkas,Dániel Kun,Balázs Ujvári,Nóra Füredi,László Ákos Kovács,Hitoshi Hashimoto,Dóra Reglődi,Viktória Kormos,Balázs Gaszner, International journal of molecular sciences, Vol. 23, No. 19, 2022/10/03
Autism-associated ANK2 regulates embryonic neurodevelopment., Shotaro Kawano,Masayuki Baba,Hotaka Fukushima,Daiki Miura,Hitoshi Hashimoto,Takanobu Nakazawa, Biochemical and biophysical research communications, Vol. 605, p. 45-50, 2022/05/21
Correction to: Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome., Tomoya Takemoto,Masayuki Baba,Kazumasa Yokoyama,Kohei Kitagawa,Kazuki Nagayasu,Yukio Ago,Kaoru Seiriki,Atsuko Hayata-Takano,Atsushi Kasai,Daisuke Mori,Norio Ozaki,Kazuhiro Takuma,Ryota Hashimoto,Hitoshi Hashimoto,Takanobu Nakazawa, Molecular brain, Vol. 15, No. 1, p. 34-34, 2022/04/11
Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome., Tomoya Takemoto,Masayuki Baba,Kazumasa Yokoyama,Kohei Kitagawa,Kazuki Nagayasu,Yukio Ago,Kaoru Seiriki,Atsuko Hayata-Takano,Atsushi Kasai,Daisuke Mori,Norio Ozaki,Kazuhiro Takuma,Ryota Hashimoto,Hitoshi Hashimoto,Takanobu Nakazawa, Molecular brain, Vol. 15, No. 1, p. 26-26, 2022/03/28
Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses., Misaki Niu,Atsushi Kasai,Masato Tanuma,Kaoru Seiriki,Hisato Igarashi,Takahiro Kuwaki,Kazuki Nagayasu,Keita Miyaji,Hiroki Ueno,Wataru Tanabe,Kei Seo,Rei Yokoyama,Jin Ohkubo,Yukio Ago,Misuzu Hayashida,Ken-Ichi Inoue,Masahiko Takada,Shun Yamaguchi,Takanobu Nakazawa,Shuji Kaneko,Hiroyuki Okuno,Akihiro Yamanaka,Hitoshi Hashimoto, Science advances, Vol. 8, No. 11, 2022/03/18
Fluoxetine treatment supports predictive validity of the three hit model of depression in male PACAP heterozygous mice and underpins the impact of early life adversity on therapeutic efficacy., Tamás Gaszner,József Farkas,Dániel Kun,Balázs Ujvári,Gergely Berta,Valér Csernus,Nóra Füredi,László Ákos Kovács,Hitoshi Hashimoto,Dóra Reglődi,Viktória Kormos,Balázs Gaszner, Frontiers in endocrinology, Vol. 13, p. 995900-995900, 2022
Vasoactive intestinal peptide-VIPR2 signaling regulates tumor cell migration., Satoshi Asano,Misa Yamasaka,Kairi Ozasa,Kotaro Sakamoto,Atsuko Hayata-Takano,Takanobu Nakazawa,Hitoshi Hashimoto,James A Waschek,Yukio Ago, Frontiers in oncology, Vol. 12, p. 852358-852358, 2022
The Protective Effects of Endogenous PACAP in Oxygen-Induced Retinopathy., Timea Kvarik,Dora Reglodi,Dora Werling,Alexandra Vaczy,Petra Kovari,Edina Szabo,Krisztina Kovacs,Hitoshi Hashimoto,Tibor Ertl,Judit Gyarmati,Tamas Atlasz, Journal of molecular neuroscience : MN, Vol. 71, No. 12, p. 2546-2557, 2021/12
Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia., Kana Yamamoto,Toshihiko Kuriu,Kensuke Matsumura,Kazuki Nagayasu,Yoshinori Tsurusaki,Noriko Miyake,Hidenaga Yamamori,Yuka Yasuda,Michiko Fujimoto,Mikiya Fujiwara,Masayuki Baba,Kohei Kitagawa,Tomoya Takemoto,Nanaka Gotoda-Nishimura,Tomohiro Takada,Kaoru Seiriki,Atsuko Hayata-Takano,Atsushi Kasai,Yukio Ago,Satoshi Kida,Kazuhiro Takuma,Fumihito Ono,Naomichi Matsumoto,Ryota Hashimoto,Hitoshi Hashimoto,Takanobu Nakazawa, Translational psychiatry, Vol. 11, No. 1, p. 548-548, 2021/10/25
Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro., Kazuyuki Togo,Hayato Fukusumi,Tomoko Shofuda,Hiroshi Ohnishi,Hiroyuki Yamazaki,Mariko Kato Hayashi,Nana Kawasaki,Nobuyuki Takei,Takanobu Nakazawa,Yumiko Saito,Kousuke Baba,Hitoshi Hashimoto,Yuko Sekino,Tomoaki Shirao,Hideki Mochizuki,Yonehiro Kanemura, Molecular brain, Springer Science and Business Media LLC, Vol. 14, No. 1, p. 149-149, 2021/10/11
The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory., Yuki Kambe,Yu Yamauchi,Trung Thanh Nguyen,Thu Thi Nguyen,Yukio Ago,Norihito Shintani,Hitoshi Hashimoto,Shimako Yoshitake,Takashi Yoshitake,Jan Kehr,Namiko Kawamura,Goro Katsuura,Takashi Kurihara,Atsuro Miyata, Pharmacological reports : PR, Vol. 73, No. 4, p. 1109-1121, 2021/08
Exploring rare cellular activity in more than one million cells by a transscale scope, T. Ichimura,T. Kakizuka,K. Horikawa,K. Seiriki,A. Kasai,H. Hashimoto,K. Fujita,T. M. Watanabe,T. Nagai, SCIENTIFIC REPORTS, NATURE PORTFOLIO, Vol. 11, No. 1, 2021/08
Comprehensive characterization of migration profiles of murine cerebral cortical neurons during development using FlashTag labeling., Satoshi Yoshinaga,Minkyung Shin,Ayako Kitazawa,Kazuhiro Ishii,Masato Tanuma,Atsushi Kasai,Hitoshi Hashimoto,Ken-Ichiro Kubo,Kazunori Nakajima, iScience, Elsevier BV, Vol. 24, No. 4, p. 102277-102277, 2021/04/23
Intranasal oxytocin administration ameliorates social behavioral deficits in a POGZWT/Q1038R mouse model of autism spectrum disorder., Kohei Kitagawa,Kensuke Matsumura,Masayuki Baba,Momoka Kondo,Tomoya Takemoto,Kazuki Nagayasu,Yukio Ago,Kaoru Seiriki,Atsuko Hayata-Takano,Atsushi Kasai,Kazuhiro Takuma,Ryota Hashimoto,Hitoshi Hashimoto,Takanobu Nakazawa, Molecular brain, Vol. 14, No. 1, p. 56-56, 2021/03/16
Altered Functional Connectivity of the Orbital Cortex and Striatum Associated with Catalepsy Induced by Dopamine D1 and D2 Antagonists, Misaki Niu,Atsushi Kasai,Kaoru Seiriki,Misuzu Hayashida,Masato Tanuma,Rei Yokoyama,Yumi Hirato,Hitoshi Hashimoto, Biological and Pharmaceutical Bulletin, Pharmaceutical Society of Japan, Vol. 44, No. 3, p. 442-447, 2021/03/01
Probing the VIPR2 Microduplication Linkage to Schizophrenia in Animal and Cellular Models., Yukio Ago,Satoshi Asano,Hitoshi Hashimoto,James A Waschek, Frontiers in neuroscience, Vol. 15, p. 717490-717490, 2021
PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization., Atsuko Hayata-Takano,Yusuke Shintani,Keita Moriguchi,Naoki Encho,Kohei Kitagawa,Takanobu Nakazawa,Hitoshi Hashimoto, Frontiers in endocrinology, Vol. 12, p. 732456-732456, 2021
Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice., Chihiro Kawaguchi,Norihito Shintani,Atsuko Hayata-Takano,Michiyoshi Hatanaka,Ai Kuromi,Reiko Nakamura,Yui Yamano,Yusuke Shintani,Katsuya Nagai,Soken Tsuchiya,Yukihiko Sugimoto,Atsushi Ichikawa,Yasushi Okuno,Yoshihiro Urade,Hiroyuki Hirai,Kin-Ya Nagata,Masataka Nakamura,Shuh Narumiya,Takanobu Nakazawa,Atsushi Kasai,Yukio Ago,Kazuhiro Takuma,Akemichi Baba,Hitoshi Hashimoto, Communications biology, Springer Science and Business Media LLC, Vol. 3, No. 1, p. 557-557, 2020/10/08
Trans-scale-scope to find rare cellular activity in sub-million cells, Taro Ichimura,Taishi Kakizuka,Kazuki Horikawa,Kaoru Seiriki,Atsushi Kasai,Hitoshi Hashimoto,Katsumasa Fujita,Tomonobu M. Watanabe,Takeharu Nagai, Cold Spring Harbor Laboratory, 2020/06/30
Pituitary Adenylate Cyclase-Activating Polypeptide in the Ventromedial Hypothalamus Is Responsible for Food Intake Behavior by Modulating the Expression of Agouti-Related Peptide in Mice., Thanh Trung Nguyen,Yuki Kambe,Takashi Kurihara,Tomoya Nakamachi,Norihito Shintani,Hitoshi Hashimoto,Atsuro Miyata, Molecular neurobiology, Vol. 57, No. 4, p. 2101-2114, 2020/04
(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression., Rei Yokoyama,Momoko Higuchi,Wataru Tanabe,Shinji Tsukada,Megumi Naito,Takumi Yamaguchi,Lu Chen,Atsushi Kasai,Kaoru Seiriki,Takanobu Nakazawa,Shinsaku Nakagawa,Kenji Hashimoto,Hitoshi Hashimoto,Yukio Ago, Pharmacology, biochemistry, and behavior, Vol. 191, p. 172876-172876, 2020/04
Direct visualization of an antidepressant analog using surface-enhanced Raman scattering in the brain., Masato Tanuma,Atsushi Kasai,Kazuki Bando,Naoyuki Kotoku,Kazuo Harada,Masafumi Minoshima,Kosuke Higashino,Atsushi Kimishima,Masayoshi Arai,Yukio Ago,Kaoru Seiriki,Kazuya Kikuchi,Satoshi Kawata,Katsumasa Fujita,Hitoshi Hashimoto, JCI insight, Vol. 5, No. 6, 2020/03/26
Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes., Kensuke Matsumura,Kaoru Seiriki,Shota Okada,Masashi Nagase,Shinya Ayabe,Ikuko Yamada,Tamio Furuse,Hirotoshi Shibuya,Yuka Yasuda,Hidenaga Yamamori,Michiko Fujimoto,Kazuki Nagayasu,Kana Yamamoto,Kohei Kitagawa,Hiroki Miura,Nanaka Gotoda-Nishimura,Hisato Igarashi,Misuzu Hayashida,Masayuki Baba,Momoka Kondo,Shigeru Hasebe,Kosei Ueshima,Atsushi Kasai,Yukio Ago,Atsuko Hayata-Takano,Norihito Shintani,Tokuichi Iguchi,Makoto Sato,Shun Yamaguchi,Masaru Tamura,Shigeharu Wakana,Atsushi Yoshiki,Ayako M Watabe,Hideyuki Okano,Kazuhiro Takuma,Ryota Hashimoto,Hitoshi Hashimoto,Takanobu Nakazawa, Nature communications, Vol. 11, No. 1, p. 859-859, 2020/02/26
Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism., Shuto Takeuchi,Takuya Kawanai,Ryosuke Yamauchi,Lu Chen,Tatsunori Miyaoka,Mei Yamada,Satoshi Asano,Atsuko Hayata-Takano,Takanobu Nakazawa,Koji Yano,Naotaka Horiguchi,Shinsaku Nakagawa,Kazuhiro Takuma,James A Waschek,Hitoshi Hashimoto,Yukio Ago, Frontiers in neuroscience, Vol. 14, p. 521-521, 2020
Autism-associated protein kinase D2 regulates embryonic cortical neuron development., Kensuke Matsumura,Masayuki Baba,Kazuki Nagayasu,Kana Yamamoto,Momoka Kondo,Kohei Kitagawa,Tomoya Takemoto,Kaoru Seiriki,Atsushi Kasai,Yukio Ago,Atsuko Hayata-Takano,Norihito Shintani,Toshihiko Kuriu,Tokuichi Iguchi,Makoto Sato,Kazuhiro Takuma,Ryota Hashimoto,Hitoshi Hashimoto,Takanobu Nakazawa, Biochemical and biophysical research communications, Vol. 519, No. 3, p. 626-632, 2019/11/12
Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome., Masayuki Baba,Kazumasa Yokoyama,Kaoru Seiriki,Yuichiro Naka,Kensuke Matsumura,Momoka Kondo,Kana Yamamoto,Misuzu Hayashida,Atsushi Kasai,Yukio Ago,Kazuki Nagayasu,Atsuko Hayata-Takano,Akinori Takahashi,Shun Yamaguchi,Daisuke Mori,Norio Ozaki,Tadashi Yamamoto,Kazuhiro Takuma,Ryota Hashimoto,Hitoshi Hashimoto,Takanobu Nakazawa, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 44, No. 12, p. 2125-2135, 2019/11
Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice., Daniel Balazs Fulop,Viktoria Humli,Judit Szepesy,Virag Ott,Dora Reglodi,Balazs Gaszner,Adrienn Nemeth,Agnes Szirmai,Laszlo Tamas,Hitoshi Hashimoto,Tibor Zelles,Andrea Tamas, Scientific reports, Vol. 9, No. 1, p. 14598-14598, 2019/10/10
(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism., Yukio Ago,Wataru Tanabe,Momoko Higuchi,Shinji Tsukada,Tatsunori Tanaka,Takumi Yamaguchi,Hisato Igarashi,Rei Yokoyama,Kaoru Seiriki,Atsushi Kasai,Takanobu Nakazawa,Shinsaku Nakagawa,Kenji Hashimoto,Hitoshi Hashimoto, The international journal of neuropsychopharmacology, Vol. 22, No. 10, p. 665-674, 2019/10/01
Modeling of psychiatric disorders using induced pluripotent stem cell-related technologies., Takanobu Nakazawa,Ryota Hashimoto,Kazuhiro Takuma,Hitoshi Hashimoto, Journal of pharmacological sciences, Vol. 140, No. 4, p. 321-324, 2019/08
Altered Notch Signaling in Developing Molar Teeth of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)-Deficient Mice, B. D. Fulop,B. Sandor,E. Szentleleky,E. Karanyicz,D. Reglodi,B. Gaszner,R. Zakany,H.Hashimoto,T. Juhasz,A. Tamas, Journal of Molecular Neuroscience, 2019/07
Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Dendritic Spine Maturation and Morphogenesis via MicroRNA-132 Upregulation., Atsuko Hayata-Takano,Toshihiko Kamo,Harui Kijima,Kaoru Seiriki,Katsuya Ogata,Yukio Ago,Takanobu Nakazawa,Yusuke Shintani,Kosuke Higashino,Kazuki Nagayasu,Norihito Shintani,Atsushi Kasai,James A Waschek,Hitoshi Hashimoto, The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 39, No. 22, p. 4208-4220, 2019/05/29
Whole-brain block-face serial microscopy tomography at subcellular resolution using FAST., Kaoru Seiriki,Atsushi Kasai,Takanobu Nakazawa,Misaki Niu,Yuichiro Naka,Masato Tanuma,Hisato Igarashi,Kosei Yamaura,Atsuko Hayata-Takano,Yukio Ago,Hitoshi Hashimoto, Nature protocols, Vol. 14, No. 5, p. 1509-1529, 2019/05
Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats., Naoya Nishitani,Kazuki Nagayasu,Nozomi Asaoka,Mayumi Yamashiro,Chihiro Andoh,Yuma Nagai,Haruko Kinoshita,Hiroyuki Kawai,Norihiro Shibui,Beihui Liu,James Hewinson,Hisashi Shirakawa,Takayuki Nakagawa,Hitoshi Hashimoto,Sergey Kasparov,Shuji Kaneko, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 44, No. 4, p. 721-732, 2019/03
Enriched environment restrains autism spectrum disorder-like phenotypes in mice prenatally exposed to valproic acid., Takuma Kazuhiro,Yamaguchi Hiroshi,Hara Yuta,Ago Yukio Ago,Kita-Takano Erika,Hasebe Shigeru,Nakazawa Takanobu,Hashimoto Hitoshi,Matsuda Toshio, Proceedings for Annual Meeting of The Japanese Pharmacological Society, Japanese Pharmacological Society, Vol. 92, No. 0, p. 3-P-022, 2019
Treatment of pregnant mice with valproic acid caused an increase in miR-132 levels in the embryonic brain., Nakazawa Takanobu,Hara Yuta,Ago Yukio,Kita-Takano Erika,Hasebe Shigeru,Hashimoto Hitoshi,Matsuda Toshio,Takuma Kazuhiro, Proceedings for Annual Meeting of The Japanese Pharmacological Society, Japanese Pharmacological Society, Vol. 92, No. 0, p. 3-P-023, 2019
[Whole-brain activity mapping at single-cell resolution]., Atsushi Kasai,Kaoru Seiriki,Hitoshi Hashimoto, Nihon yakurigaku zasshi. Folia pharmacologica Japonica, Vol. 153, No. 6, p. 278-283, 2019
Association of Serotonin2c Receptor Polymorphisms With Antipsychotic Drug Response in Schizophrenia., Jiang Li,Hitoshi Hashimoto,Herbert Y Meltzer, Frontiers in psychiatry, Vol. 10, p. 58-58, 2019
mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model., Haruki Kawase,Yukio Ago,Megumi Naito,Momoko Higuchi,Yuta Hara,Shigeru Hasebe,Shinji Tsukada,Atsushi Kasai,Takanobu Nakazawa,Tadashi Mishina,Hiroyuki Kouji,Kazuhiro Takuma,Hitoshi Hashimoto, Pharmacology, biochemistry, and behavior, Vol. 176, p. 1-5, 2019/01
VPAC1 receptors play a dominant role in PACAP-induced vasorelaxation in female mice., Ivan Ivic,Marta Balasko,Balazs D Fulop,Hitoshi Hashimoto,Gabor Toth,Andrea Tamas,Tamas Juhasz,Akos Koller,Dora Reglodi,Margit Solymár, PloS one, Vol. 14, No. 1, 2019
Saturated excitation microscopy using differential excitation for efficient detection of nonlinear fluorescence signals, Yasunori Nawa,Yasuo Yonemaru,Atsushi Kasai,Ryosuke Oketani,Hitoshi Hashimoto,Nicholas I. Smith,Katsumasa Fujita, APL Photonics, AIP Publishing, Vol. 3, No. 8, p. 080805-080805, 2018/08
Accelerated pre-senile systemic amyloidosis in PACAP knockout mice - a protective role of PACAP in age-related degenerative processes., Dora Reglodi,Adel Jungling,Rémi Longuespée,Joerg Kriegsmann,Rita Casadonte,Mark Kriegsmann,Tamas Juhasz,Sebastian Bardosi,Andrea Tamas,Balazs Daniel Fulop,Krisztina Kovacs,Zsuzsanna Nagy,Jason Sparks,Attila Miseta,Gabriel Mazzucchelli,Hitoshi Hashimoto,Attila Bardosi, The Journal of pathology, Vol. 245, No. 4, p. 478-490, 2018/08
Knockdown of the mitochondria-localized protein p13 protects against experimental parkinsonism, Naoki Inoue,Sae Ogura,Atsushi Kasai,Takanobu Nakazawa,Kazuya Ikeda,Shintaro Higashi,Ayako Isotani,Kousuke Baba,Hideki Mochizuki,Harutoshi Fujimura,Yukio Ago,Atsuko Hayata-Takano,Kaoru Seiriki,Yusuke Shintani,Norihito Shintani,Hitoshi Hashimoto, EMBO Reports, Wiley-VCH Verlag, Vol. 19, No. 3, 2018/03/01
[Pathophysiological implication of the VPAC2 receptor in psychiatric disorders]., Ago Y,Hayata A,Hashimoto H, Nihon yakurigaku zasshi. Folia pharmacologica Japonica, Vol. 151, No. 6, p. 249-253, 2018
Disturbed spermatogenic signaling in pituitary adenylate cyclase activating polypeptide-deficient Mice, D. Reglodi,S. Cseh,B. Somoskoi,B. D. Fulop,E. Szentleleky,V. Szegeczki,A. Kovacs,A. Varga,P. Kiss,H. Hashimoto,A. Tamas,A. Bardosi,S. Manavalan,E. Bako,R. Zakany,T. Juhasz, Reproduction, BioScientifica Ltd., Vol. 155, No. 2, p. 129-139, 2018
β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking., Yusuke Shintani,Atsuko Hayata-Takano,Keita Moriguchi,Takanobu Nakazawa,Yukio Ago,Atsushi Kasai,Kaoru Seiriki,Norihito Shintani,Hitoshi Hashimoto, PloS one, Vol. 13, No. 5, 2018
Unbiased compound screening with a reporter gene assay highlights the role of p13 in the cardiac cellular stress response, Naoki Inoue,Taisei Hirouchi,Atsushi Kasai,Shintaro Higashi,Natsumi Hiraki,Shota Tanaka,Takanobu Nakazawa,Kazuto Nunomura,Bangzhong Lin,Akiko Omori,Atsuko Hayata-Takano,Yoon-Jeong Kim,Takefumi Doi,Akemichi Baba,Hitoshi Hashimoto,Norihito Shintani, Biochemical and Biophysical Research Communications, Vol. 495, No. 2, p. 1992-1997, 2018/01
プロスタグランジンD2受容体DP1を介したマウス神経細胞の形態変化の解析, 奥田健太,早田敦子,毛利育子,新谷勇介,加茂俊彦,中澤敬信,谷池雅子,橋本均, Vol. 1, 2017/11
Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice, Yuta Hara,Yukio Ago,Atsuki Taruta,Shigeru Hasebe,Haruki Kawase,Wataru Tanabe,Shinji Tsukada,Takanobu Nakazawa,Hitoshi Hashimoto,Toshio Matsuda,Kazuhiro Takuma, PSYCHOPHARMACOLOGY, SPRINGER, Vol. 234, No. 21, p. 3217-3228, 2017/11
Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism, Yuta Hara,Yukio Ago,Momoko Higuchi,Shigeru Hasebe,Takanobu Nakazawa,Hitoshi Hashimoto,Toshio Matsuda,Kazuhiro Takuma, HORMONES AND BEHAVIOR, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 96, p. 130-136, 2017/11
Impaired extinction of cued fear memory and abnormal dendritic morphology in the prelimbic and infralimbic cortices in VPAC2 receptor (VIPR2)-deficient mice, Yukio Ago,Atsuko Hayata-Takano,Takuya Kawanai,Ryosuke Yamauchi,Shuto Takeuchi,Jesse D. Cushman,Abha K. Rajbhandari,Michael S. Fanselow,Hitoshi Hashimoto,James A. Waschek, NEUROBIOLOGY OF LEARNING AND MEMORY, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 145, p. 222-231, 2017/11
Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice, Hiroshi Yamaguchi,Yuta Hara,Yukio Ago,Erika Takano,Shigeru Hasebe,Takanobu Nakazawa,Hitoshi Hashimoto,Toshio Matsuda,Kazuhiro Takuma, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 333, p. 67-73, 2017/08
Psychopharmacology of combined activation of the serotonin(1A) and sigma(1) receptors, Yukio Ago,Shigeru Hasebe,Naoki Hiramatsu,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 809, p. 172-177, 2017/08
High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates, Kaoru Seiriki,Atsushi Kasai,Takeshi Hashimoto,Wiebke Schulze,Misaki Niu,Shun Yamaguchi,Takanobu Nakazawa,Ken-ichi Inoue,Shiori Uezono,Masahiko Takada,Yuichiro Naka,Hisato Igarashi,Masato Tanuma,James A. Waschek,Yukio Ago,Kenji F. Tanaka,Atsuko Hayata-Takano,Kazuki Nagayasu,Norihito Shintani,Ryota Hashimoto,Yasuto Kunii,Mizuki Hino,Junya Matsumoto,Hirooki Yabe,Takeharu Nagai,Katsumasa Fujita,Toshio Matsuda,Kazuhiro Takuma,Akemichi Baba,Hitoshi Hashimoto, NEURON, CELL PRESS, Vol. 94, No. 6, p. 1085-+, 2017/06
CONSTRUCT AND FACE VALIDITY OF A NEW MODEL FOR THE THREE-HIT THEORY OF DEPRESSION USING PACAP MUTANT MICE ON CD1 BACKGROUND, Jozsef Farkas,Laszlo A. Kovacs,Laszlo Gaspar,Anna Nafz,Tamas Gaszner,Balazs Ujvari,Viktoria Kormos,Valer Csernus,Hitoshi Hashimoto,Dora Reglodi,Balazs Gaszner, NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 354, p. 11-29, 2017/06
Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain, Yuta Hara,Yukio Ago,Erika Takano,Shigeru Hasebe,Takanobu Nakazawa,Hitoshi Hashimoto,Toshio Matsuda,Kazuhiro Takuma, MOLECULAR AUTISM, BIOMED CENTRAL LTD, Vol. 8, 2017/06
Implantable optogenetic device with CMOS IC technology for simultaneous optical measurement and stimulation, Makito Haruta,Naoya Kamiyama,Shun Nakajima,Mayumi Motoyama,Mamiko Kawahara,Yasumi Ohta,Atsushi Yamasaki,Hiroaki Takehara,Toshihiko Noda,Kiyotaka Sasagawa,Yasuyuki Ishikawa,Takashi Tokuda,Hitoshi Hashimoto,Jun Ohta, JAPANESE JOURNAL OF APPLIED PHYSICS, IOP PUBLISHING LTD, Vol. 56, No. 5, 2017/05
Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior, Yuki Fujita,Koji Masuda,Masashige Bando,Ryuichiro Nakato,Yuki Katou,Takashi Tanaka,Masahiro Nakayama,Keizo Takao,Tsuyoshi Miyakawa,Tatsunori Tanaka,Yukio Ago,Hitoshi Hashimoto,Katsuhiko Shirahige,Toshihide Yamashita, JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIV PRESS, Vol. 214, No. 5, p. 1431-1452, 2017/05
Backup Mechanisms Maintain PACAP/VIP-Induced Arterial Relaxations in Pituitary Adenylate Cyclase-Activating Polypeptide-Deficient Mice, Ivan Ivic,Balazs D. Fulop,Tamas Juhasz,Dora Reglodi,Gabor Toth,Hitoshi Hashimoto,Andrea Tamas,Akos Koller, Journal of Vascular Research, S. Karger AG, Vol. 54, No. 3, p. 180-192, 2017/05/01
Role of Prefrontal Serotonergic and Dopaminergic Systems in Encounter-Induced Hyperactivity in Methamphetamine-Sensitized Mice, Tatsunori Tanaka,Yukio Ago,Chiaki Umehara,Emina Imoto,Shigeru Hasebe,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, OXFORD UNIV PRESS, Vol. 20, No. 5, p. 410-421, 2017/05
Implantable optogenetic device with CMOS IC technology for simultaneous optical measurement and stimulation, Makito Haruta,Naoya Kamiyama,Shun Nakajima,Mayumi Motoyama,Mamiko Kawahara,Yasumi Ohta,Atsushi Yamasaki,Hiroaki Takehara,Toshihiko Noda,Kiyotaka Sasagawa,Yasuyuki Ishikawa,Takashi Tokuda,Hitoshi Hashimoto,Jun Ohta, JAPANESE JOURNAL OF APPLIED PHYSICS, IOP PUBLISHING LTD, Vol. 56, No. 5, 2017/05
Early Neurobehavioral Development of Mice Lacking Endogenous PACAP, Jozsef Farkas,Balazs Sandor,Andrea Tamas,Peter Kiss,Hitoshi Hashimoto,Andras D. Nagy,Balazs D. Fulop,Tamas Juhasz,Sridharan Manavalan,Dora Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 61, No. 4, p. 468-478, 2017/04
Early Neurobehavioral Development of Mice Lacking Endogenous PACAP, Jozsef Farkas,Balazs Sandor,Andrea Tamas,Peter Kiss,Hitoshi Hashimoto,Andras D. Nagy,Balazs D. Fulop,Tamas Juhasz,Sridharan Manavalan,Dora Reglodi, Journal of Molecular Neuroscience, Springer New York LLC, Vol. 61, No. 4, p. 468-478, 2017/04/01
Astrocyte-neuron lactate shuttle, the major effector of astrocytic PACAP signaling for CNS functions, Kambe Yuki,Yokai Masafumi,Nakashima Yu,Shintani Norihito,Hashimoto Hitoshi,Takasaki Ichiro,Kurihara Takashi,Miyata Atsuro, JOURNAL OF PHARMACOLOGICAL SCIENCES, Vol. 133, No. 3, 2017/03
Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells frommonozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine, Takanobu Nakazawa,Masataka Kikuchi,Mitsuru Ishikawa,Hidenaga Yamamori,Kazuki Nagayasu,Takuya Matsumoto,Michiko Fujimoto,Yuka Yasuda,Mikiya Fujiwara,Shota Okada,Kensuke Matsumura,Atsushi Kasai,Atsuko Hayata-Takano,Norihito Shintani,Shusuke Numata,Kazuhiro Takuma,Wado Akamatsu,Hideyuki Okano,Akihiro Nakaya,Hitoshi Hashimoto,Ryota Hashimoto, SCHIZOPHRENIA RESEARCH, ELSEVIER SCIENCE BV, Vol. 181, p. 75-82, 2017/03
Effect of Clozapine on DNA Methylation in Peripheral Leukocytes from Patients with Treatment-Resistant Schizophrenia, Makoto Kinoshita,Shusuke Numata,Atsushi Tajima,Hidenaga Yamamori,Yuka Yasuda,Michiko Fujimoto,Shinya Watanabe,Hidehiro Umehara,Shinji Shimodera,Takanobu Nakazawa,Masataka Kikuchi,Akihiro Nakaya,Hitoshi Hashimoto,Issei Imoto,Ryota Hashimoto,Tetsuro Ohmori, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MDPI AG, Vol. 18, No. 3, 2017/03
Pituitary adenylate cyclase-activating polypeptide promotes eccrine gland sweat secretion, S. Sasaki,J. Watanabe,H. Ohtaki,M. Matsumoto,N. Murai,T. Nakamachi,J. Hannibal,J. Fahrenkrug,H. Hashimoto,H. Watanabe,H. Sueki,K. Honda,A. Miyazaki,S. Shioda, British Journal of Dermatology, Vol. 176, No. 2, p. 413-422, 2017/02/01
Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice, S. Hasebe,Y. Ago,Y. Watabe,S. Oka,N. Hiramatsu,T. Tanaka,C. Umehara,H. Hashimoto,K. Takuma,T. Matsuda, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 174, No. 4, p. 314-327, 2017/02
Backup Mechanisms Maintain PACAP/VIP-Induced Arterial Relaxations in Pituitary Adenylate Cyclase-Activating Polypeptide-Deficient Mice, Ivan Ivic,Balazs D. Fulop,Tamas Juhasz,Dora Reglodi,Gabor Toth,Hitoshi Hashimoto,Andrea Tamas,Akos Koller, JOURNAL OF VASCULAR RESEARCH, KARGER, Vol. 54, No. 3, p. 180-192, 2017
Aging-Induced Modulation of Pituitary Adenylate Cyclase-Activating Peptide- and Vasoactive Intestinal Peptide-Induced Vasomotor Responses in the Arteries of Mice, Ivan Ivic,Margit Solymar,Balazs D. Fulop,Hitoshi Hashimoto,Gabor Toth,Andrea Tamas,Tamas Juhasz,Akos Koller,Dora Reglodi, JOURNAL OF VASCULAR RESEARCH, KARGER, Vol. 54, No. 6, p. 359-366, 2017
Prostaglandin D-2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction, Yusuke Onaka,Norihito Shintani,Takanobu Nakazawa,Takuya Kanoh,Yukio Ago,Toshio Matsuda,Ryota Hashimoto,Kazutaka Ohi,Hiroyuki Hirai,Kin-ya Nagata,Masataka Nakamura,Atsushi Kasai,Atsuko Hayata-Takano,Kazuki Nagayasu,Kazuhiro Takuma,Asao Ogawa,Akemichi Baba,Hitoshi Hashimoto, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 314, p. 77-86, 2016/11
Double In situ Hybridization for MicroRNAs and mRNAs in Brain Tissues, Atsushi Kasai,Sora Kakihara,Hiroki Miura,Ryo Okada,Atsuko Hayata-Takano,Keisuke Hazama,Misaki Niu,Norihito Shintani,Takanobu Nakazawa,Hitoshi Hashimoto, FRONTIERS IN MOLECULAR NEUROSCIENCE, FRONTIERS MEDIA SA, Vol. 9, 2016/11
Critical involvement of the orbitofrontal cortex in hyperlocomotion induced by NMDA receptor blockade in mice, Kaoru Seiriki,Atsushi Kasai,Takahiro Kuwaki,Takanobu Nakazawa,Shun Yamaguchi,Hitoshi Hashimoto, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 480, No. 4, p. 558-563, 2016/11
Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation, Takuya Kawanai,Yukio Ago,Ryo Watanabe,Aya Inoue,Atsuki Taruta,Yusuke Onaka,Shigeru Hasebe,Hitoshi Hashimoto,Toshio Matsuda,Kazuhiro Takuma, NEUROCHEMICAL RESEARCH, SPRINGER/PLENUM PUBLISHERS, Vol. 41, No. 10, p. 2574-2584, 2016/10
Improvement by Methylphenidate and Atomoxetine of Social Interaction Deficits and Recognition Memory Impairment in a Mouse Model of Valproic Acid-Induced Autism, Yuta Hara,Yukio Ago,Atsuki Taruta,Keisuke Katashiba,Shigeru Hasebe,Erika Takano,Yusuke Onaka,Hitoshi Hashimoto,Toshio Matsuda,Kazuhiro Takuma, AUTISM RESEARCH, WILEY, Vol. 9, No. 9, p. 926-939, 2016/09
Involvement of GABA(A) receptors in 5-HT1A and sigma(1) receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency, Yukio Ago,Shigeru Hasebe,Naoki Hiramatsu,Kazuya Mori,Yuji Watabe,Yusuke Onaka,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, PSYCHOPHARMACOLOGY, SPRINGER, Vol. 233, No. 17, p. 3125-3134, 2016/09
REDUCED RESPONSE TO CHRONIC MILD STRESS IN PACAP MUTANT MICE IS ASSOCIATED WITH BLUNTED FOSB EXPRESSION IN LIMBIC FOREBRAIN AND BRAINSTEM CENTERS, Viktoria Kormos,Laszlo Gaspar,Laszlo A. Kovacs,Jozsef Farkas,Tamas Gaszner,Valer Csernus,Andras Balogh,Hitoshi Hashimoto,Dora Reglodi,Zsuzsanna Helyes,Balazs Gaszner, NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 330, p. 335-358, 2016/08
PACAP suppresses dry eye signs by stimulating tear secretion., Tomoya Nakamachi,Hirokazu Ohtaki,Tamotsu Seki,Sachiko Yofu,Nobuyuki Kagami,Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Laszlo Mark,Ingela Lanekoff,Peter Kiss,Jozsef Farkas,Dora Reglodi,Seiji Shioda, Nature communications, Vol. 7, p. 12034-12034, 2016/06/27
Structural and Morphometric Comparison of Lower Incisors in PACAP-Deficient and Wild-Type Mice, B. Sandor,K. Fintor,D. Reglodi,D. B. Fulop,Z. Helyes,I. Szanto,P. Nagy,H. Hashimoto,A. Tamas, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 59, No. 2, p. 300-308, 2016/06
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Regulates the Hypothalamo-Pituitary-Thyroid (HPT) Axis via Type 2 Deiodinase in Male Mice, P. Egri,C. Fekete,A. Denes,D. Reglodi,H. Hashimoto,B. D. Fulop,Balazs Gereben, ENDOCRINOLOGY, ENDOCRINE SOC, Vol. 157, No. 6, p. 2356-2366, 2016/06
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke., Minako Matsumoto,Tomoya Nakamachi,Jun Watanabe,Koichi Sugiyama,Hirokazu Ohtaki,Norimitsu Murai,Shun Sasaki,Zhifang Xu,Hitoshi Hashimoto,Tamotsu Seki,Akira Miyazaki,Seiji Shioda, Journal of molecular neuroscience : MN, Vol. 59, No. 2, p. 270-9, 2016/06
Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders (vol 7, pg 10594, 2016), Takanobu Nakazawa,Ryota Hashimoto,Kazuto Sakoori,Yuki Sugaya,Asami Tanimura,Yuki Hashimotodani,Kazutaka Ohi,Hidenaga Yamamori,Yuka Yasuda,Satomi Umeda-Yano,Yuji Kiyama,Kohtarou Konno,Takeshi Inoue,Kazumasa Yokoyama,Takafumi Inoue,Shusuke Numata,Tohru Ohnuma,Nakao Iwata,Norio Ozaki,Hitoshi Hashimoto,Masahiko Watanabe,Toshiya Manabe,Tadashi Yamamoto,Masatoshi Takeda,Masanobu Kano, NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, Vol. 7, 2016/04
[The novel method female encounter test]., Ago Y,Hasebe S,Hashimoto H,Takuma K,Matsuda T, Nihon yakurigaku zasshi. Folia pharmacologica Japonica, The Japanese Pharmacological Society, Vol. 147, No. 4, p. 230-234, 2016/04
Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder, Ryota Hashimoto,Takanobu Nakazawa,Yoshinori Tsurusaki,Yuka Yasuda,Kazuki Nagayasu,Kensuke Matsumura,Hitoshi Kawashima,Hidenaga Yamamori,Michiko Fujimoto,Kazutaka Ohi,Satomi Umeda-Yano,Masaki Fukunaga,Haruo Fujino,Atsushi Kasai,Atsuko Hayata-Takano,Norihito Shintani,Masatoshi Takeda,Naomichi Matsumoto,Hitoshi Hashimoto, JOURNAL OF HUMAN GENETICS, NATURE PUBLISHING GROUP, Vol. 61, No. 3, p. 199-206, 2016/03
Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse, K. Fujiwara,Y. Fujita,A. Kasai,Y. Onaka,H. Hashimoto,H. Okada,T. Yamashita, TRANSLATIONAL PSYCHIATRY, NATURE PUBLISHING GROUP, Vol. 6, 2016/03
Pituitary adenylate cyclase-activating polypeptide (PACAP) contributes to the proliferation of hematopoietic progenitor cells in murine bone marrow via PACAP-specific receptor., Zhifang Xu,Hirokazu Ohtaki,Jun Watanabe,Kazuyuki Miyamoto,Norimitsu Murai,Shun Sasaki,Minako Matsumoto,Hitoshi Hashimoto,Yutaka Hiraizumi,Satoshi Numazawa,Seiji Shioda, Scientific reports, Vol. 6, p. 22373-22373, 2016/02/29
Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice, Kosuke Higashino,Yukio Ago,Takahiro Umeki,Shigeru Hasebe,Yusuke Onaka,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, PSYCHOPHARMACOLOGY, SPRINGER, Vol. 233, No. 3, p. 521-528, 2016/02
Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders, Takanobu Nakazawa,Ryota Hashimoto,Kazuto Sakoori,Yuki Sugaya,Asami Tanimura,Yuki Hashimotodani,Kazutaka Ohi,Hidenaga Yamamori,Yuka Yasuda,Satomi Umeda-Yano,Yuji Kiyama,Kohtarou Konno,Takeshi Inoue,Kazumasa Yokoyama,Takafumi Inoue,Shusuke Numata,Tohru Ohnuma,Nakao Iwata,Norio Ozaki,Hitoshi Hashimoto,Masahiko Watanabe,Toshiya Manabe,Tadashi Yamamoto,Masatoshi Takeda,Masanobu Kano, NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, Vol. 7, 2016/02
PACAP Protects the Adolescent and Adult Mice Brain from Ethanol Toxicity and Modulates Distinct Sets of Genes Regulating Similar Networks., Lacaille Helene,Duterte-Boucher Dominique,Vaudry Hubert,Zerdoumi Yasmine,Flaman Jean-Michel,Hashimoto Hitoshi,Vaudry David, Molecular neurobiology, 2016
High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance, Masanori Nakata,Boyang Zhang,Yifei Yang,Takashi Okada,Norihito Shintani,Hitoshi Hashimoto,Toshihiko Yada, JOURNAL OF DIABETES RESEARCH, HINDAWI PUBLISHING CORP, 2016
De novo POGZ mutations in sporadic autism disrupt the DNA-binding activity of POGZ., Matsumura Kensuke,Nakazawa Takanobu,Nagayasu Kazuki,Gotoda-Nishimura Nanaka,Kasai Atsushi,Hayata-Takano Atsuko,Shintani Norihito,Yamamori Hidenaga,Yasuda Yuka,Hashimoto Ryota,Hashimoto Hitoshi, Journal of molecular psychiatry, Vol. 4, 2016
Structured line illumination Raman microscopy, Kozue Watanabe,Almar F. Palonpon,Nicholas I. Smith,Liang-da Chiu,Atsushi Kasai,Hitoshi Hashimoto,Satoshi Kawata,Katsumasa Fujita, NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, Vol. 6, 2015/12
The Female Encounter Test: A Novel Method for Evaluating Reward-Seeking Behavior or Motivation in Mice, Yukio Ago,Shigeru Hasebe,Saki Nishiyama,Satoshi Oka,Yusuke Onaka,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, OXFORD UNIV PRESS, Vol. 18, No. 11, 2015/10
Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice, Shigeru Hasebe,Yukio Ago,Saki Nishiyama,Satoshi Oka,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, BEHAVIOURAL PHARMACOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 26, No. 7, p. 681-690, 2015/10
Pituitary Adenylate Cyclase-Activating Polypeptide Is Upregulated in Murine Skin Inflammation and Mediates Transient Receptor Potential Vanilloid-1-Induced Neurogenic Edema, Zsuzsanna Helyes,Jozsef Kun,Nora Dobrosi,Katalin Sandor,Jozsef Nemeth,Aniko Perkecz,Erika Pinter,Krisztina Szabadfi,Balazs Gaszner,Valeria Tekus,Janos Szolcsanyi,Martin Steinhoff,Hitoshi Hashimoto,Dora Reglodi,Tamas Biro, JOURNAL OF INVESTIGATIVE DERMATOLOGY, ELSEVIER SCIENCE INC, Vol. 135, No. 9, p. 2209-2218, 2015/09
Decreased expression of hippocampal Na+/Ca2+ exchanger isoform-1 by pentylenetetrazole kindling in mice, Takuya Kawanai,Atsuki Taruta,Aya Inoue,Ryo Watanabe,Yukio Ago,Hitoshi Hashimoto,Shigeru Hasebe,Yasuhiro Ooi,Kazuhiro Takuma,Toshio Matsuda, EPILEPSY RESEARCH, ELSEVIER SCIENCE BV, Vol. 115, p. 109-112, 2015/09
Reduced prefrontal dopaminergic activity in valproic acid-treated mouse autism model, Yuta Hara,Kazuhiro Takuma,Erika Takano,Keisuke Katashiba,Atsuki Taruta,Kosuke Higashino,Hitoshi Hashimoto,Yukio Ago,Toshio Matsuda, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 289, p. 39-47, 2015/08
Activation of glycogen metabolism by pituitary adenylate cyclase-activating polypeptide in cultured astrocyte, Kambe, Yuki,Nakashima, Yu,Shintani, Norihito,Hashimoto, Hitoshi,Miyata, Atsuro, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 128, No. 3, p. S89-S89, 2015/07
Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice, Kazuya Ikeda,Shuhei Tomimoto,Soken Tsuchiya,Ken-Ichi Hamagami,Norihito Shintani,Yukihiko Sugimoto,Atsushi Ichikawa,Atsushi Kasai,Takanobu Nakazawa,Kazuki Nagayasu,Atsuko Hayata-Takano,Akemichi Baba,Hitoshi Hashimoto, Biochemistry and Biophysics Reports, Elsevier, Vol. 2, p. 179-183, 2015/07/01
p13 overexpression in pancreatic beta-cells ameliorates type 2 diabetes in high-fat-fed mice, Shintaro Higashi,Kazuhiko Katagi,Norihito Shintani,Kazuya Ikeda,Yukihiko Sugimoto,Soken Tsuchiya,Naoki Inoue,Shota Tanaka,Mai Koumoto,Atsushi Kasai,Takanobu Nakazawa,Atsuko Hayata-Takano,Ken-Ichi Hamagami,Shuhei Tomimoto,Takuya Yoshida,Tadayasu Ohkubo,Kazuki Nagayasu,Yukio Ago,Yusuke Onaka,Ryota Hashimoto,Atsushi Ichikawa,Akemichi Baba,Hitoshi Hashimoto, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 461, No. 4, p. 612-617, 2015/06
Reductions in synaptic proteins and selective alteration of prepulse inhibition in male C57BL/6 mice after postnatal administration of a VIP receptor (VIPR2) agonist, Yukio Ago,Michael C. Condro,Yossan-Var Tan,Cristina A. Ghiani,Christopher S. Colwell,Jesse D. Cushman,Michael S. Fanselow,Hitoshi Hashimoto,James A. Waschek, PSYCHOPHARMACOLOGY, SPRINGER, Vol. 232, No. 12, p. 2181-2189, 2015/06
ATOMOXETINE REVERSES LOCOMOTOR HYPERACTIVITY, IMPAIRED NOVEL OBJECT RECOGNITION, AND PREPULSE INHIBITION IMPAIRMENT IN MICE LACKING PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, Y. Shibasaki,A. Hayata-Takano,K. Hazama,T. Nakazawa,N. Shintani,A. Kasai,K. Nagayasu,R. Hashimoto,M. Tanida,T. Katayama,S. Matsuzaki,K. Yamada,M. Taniike,Y. Onaka,Y. Ago,J. A. Waschek,K. Koeves,D. Regloedi,A. Tamas,T. Matsuda,A. Baba,H. Hashimoto, NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 297, p. 95-104, 2015/06
CRTH2, a prostaglandin D-2 receptor, mediates depression-related behavior in mice, Yusuke Onaka,Norihito Shintani,Takanobu Nakazawa,Ryota Haba,Yukio Ago,Hyper Wang,Takuya Kanoh,Atsuko Hayata-Takano,Hiroyuki Hirai,Kin-ya Nagata,Masataka Nakamura,Ryota Hashimoto,Toshio Matsuda,James A. Waschek,Atsushi Kasai,Kazuki Nagayasu,Akemichi Baba,Hitoshi Hashimoto, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 284, p. 131-137, 2015/05
Anxiolytic-like effects of restraint during the dark cycle in adolescent mice, Yuki Ota,Yukio Ago,Tatsunori Tanaka,Shigeru Hasebe,Yui Toratani,Yusuke Onaka,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 284, p. 103-111, 2015/05
Simultaneous neuron- and astrocyte-specific fluorescent marking, Wiebke Schulze,Atsuko Hayata-Takano,Toshihiko Kamo,Takanobu Nakazawa,Kazuki Nagayasu,Atsushi Kasai,Kaoru Seiriki,Norihito Shintani,Yukio Ago,Camille Farfan,Ryota Hashimoto,Akemichi Baba,Hitoshi Hashimoto, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 459, No. 1, p. 81-86, 2015/03
PACAP Enhances Axon Outgrowth in Cultured Hippocampal Neurons to a Comparable Extent as BDNF, Katsuya Ogata,Norihito Shintani,Atsuko Hayata-Takano,Toshihiko Kamo,Shintaro Higashi,Kaoru Seiriki,Hisae Momosaki,David Vaudry,Hubert Vaudry,Ludovic Galas,Atsushi Kasai,Kazuki Nagayasu,Takanobu Nakazawa,Ryota Hashimoto,Yukio Ago,Toshio Matsuda,Akemichi Baba,Hitoshi Hashimoto, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 10, No. 3, 2015/03
A Mouse Model of Human Primitive Neuroectodermal Tumors Resulting from Microenvironmentally-Driven Malignant Transformation of Orthotopically Transplanted Radial Glial Cells, Sergey Malchenko,Simone Treiger Sredni,Hitoshi Hashimoto,Atsushi Kasai,Kazuki Nagayasu,Jianping Xie,Naira V. Margaryan,Kaoru Seiriki,Rishi R. Lulla,Richard E. B. Seftor,Lauren M. Pachman,Herbert Y. Meltzer,Mary J. C. Hendrix,Marcelo B. Soares, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 10, No. 3, 2015/03
Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP)., Tomomi Tsumuraya,Hirokazu Ohtaki,Dandan Song,Atsushi Sato,Jun Watanabe,Yutaka Hiraizumi,Tomoya Nakamachi,Zhifang Xu,Kenji Dohi,Hitoshi Hashimoto,Takashi Atsumi,Seiji Shioda, Journal of neuroinflammation, Vol. 12, p. 35-35, 2015/02/22
Role of the 5-HT1A autoreceptor in the enhancement of fluvoxamine-induced increases in prefrontal dopamine release by adrenalectomy/castration in mice, Shigeru Hasebe,Naoki Hiramatsu,Yukio Ago,Kazuya Mori,Yuji Watabe,Hitoshi Hashimoto,Kazuhiro Takuma,Toshio Matsuda, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 127, No. 2, p. 232-235, 2015/02
Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-beta (TGF-beta) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro, Atsushi Yamasaki,Atsushi Kasai,Akihiro Toi,Maki Kurita,Saki Kimoto,Atsuko Hayata-Takano,Takanobu Nakazawa,Kazuki Nagayasu,Norihito Shintani,Ryota Hashimoto,Akira Ito,Herbert Y. Meltzer,Yukio Ago,James A. Waschek,Yusuke Onaka,Toshio Matsuda,Akemichi Baba,Hitoshi Hashimoto, JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Vol. 132, No. 4, p. 418-428, 2015/02
Enhancement of the lateral resolution of Raman microscopy by use of structured illumination, Almar F. Palonpon,Kozue Watanabe,Nicholas I. Smith,Liang Da Chiu,Atsushi Kasai,Hitoshi Hashimoto,Satoshi Kawata,Katsumasa Fujita, Optics InfoBase Conference Papers, Vol. Part F132-JSAP 2019, 2015
Structural and Morphometric Comparison of the Molar Teeth in Pre-eruptive Developmental Stage of PACAP-Deficient and Wild-Type Mice, B. Sandor,K. Fintor,Sz. Felszeghy,T. Juhasz,D. Reglodi,L. Mark,P. Kiss,A. Jungling,B. D. Fulop,A. D. Nagy,H. Hashimoto,R. Zakany,A. Nagy,A. Tamas, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 54, No. 3, p. 331-341, 2014/11
Comparative Protein Composition of the Brains of PACAP-Deficient Mice Using Mass Spectrometry-Based Proteomic Analysis, G. Maasz,Z. Pirger,D. Reglodi,D. Petrovics,J. Schmidt,P. Kiss,A. Rivnyak,H. Hashimoto,P. Avar,E. Jambor,A. Tamas,B. Gaszner,L. Mark, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 54, No. 3, p. 310-319, 2014/11
Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism, Kazuhiro Takuma,Yuta Hara,Shunsuke Kataoka,Takuya Kawanai,Yuko Maeda,Ryo Watanabe,Erika Takano,Atsuko Hayata-Takano,Hitoshi Hashimoto,Yukio Ago,Toshio Matsuda, PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 126, p. 43-49, 2014/11
Characterization of the Thermoregulatory Response to Pituitary Adenylate Cyclase-Activating Polypeptide in Rodents, Eszter Banki,Eszter Pakai,Balazs Gaszner,Csaba Zsiboras,Andras Czett,Paras Rahul Parkash Bhuddi,Hitoshi Hashimoto,Gabor Toth,Andrea Tamas,Dora Reglodi,Andras Garami, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 54, No. 3, p. 543-554, 2014/11
Suppression of spinal cord injury on human mesenchymal stem/progenitor cells (MSCs) mediated by pituitary adenylate cyclase activating polypeptide (PACAP), Ohtaki Hirokazu,Tsumuraya Tomomi,Sato Atsushi,Xu Zhifang,Miyamoto Kazuyuki,Watanabe Jun,Nakamachi Tomoya,Hashimoto Hitoshi,Shioda Seiji, JOURNAL OF NEUROIMMUNOLOGY, Vol. 275, No. 1-2, p. 166-167, 2014/10/15
Differential Regulatory Role of Pituitary Adenylate Cyclase-Activating Polypeptide in the Serum-Transfer Arthritis Model, Balint Botz,Kata Bolcskei,Laszlo Kereskai,Miklos Kovacs,Tamas Nemeth,Krisztian Szigeti,Ildiko Horvath,Domokos Mathe,Noemi Kovacs,Hitoshi Hashimoto,Dora Reglodi,Janos Szolcsanyi,Erika Pinter,Attila Mocsai,Zsuzsanna Helyes, ARTHRITIS & RHEUMATOLOGY, WILEY-BLACKWELL, Vol. 66, No. 10, p. 2739-2750, 2014/10
Behavioral characterization of mice overexpressing human dysbindin-1, Norihito Shintani,Yusuke Onaka,Ryota Hashimoto,Hironori Takamura,Tsuyoshi Nagata,Satomi Umeda-Yano,Akihiro Mouri,Takayoshi Mamiya,Ryota Haba,Shinsuke Matsuzaki,Taiichi Katayama,Hidenaga Yamamori,Takanobu Nakazawa,Kazuki Nagayasu,Yukio Ago,Yuki Yagasaki,Toshitaka Nabeshima,Masatoshi Takeda,Hitoshi Hashimoto, MOLECULAR BRAIN, BIOMED CENTRAL LTD, Vol. 7, 2014/10
An enriched environment ameliorates memory impairments in PACAP-deficient mice, Kazuhiro Takuma,Yuko Maeda,Yukio Ago,Toshihiro Ishihama,Kosuke Takemoto,Akira Nakagawa,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 272, p. 269-278, 2014/10
Increased Behavioral and Neuronal Responses to a Hallucinogenic Drug in PACAP Heterozygous Mutant Mice, Keisuke Hazama,Atsuko Hayata-Takano,Kazuki Uetsuki,Atsushi Kasai,Naoki Encho,Norihito Shintani,Kazuki Nagayasu,Ryota Hashimoto,Dora Reglodi,Tsuyoshi Miyakawa,Takanobu Nakazawa,Akemichi Baba,Hitoshi Hashimoto, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 9, No. 2, 2014/02
Central CRTH2, a Second Prostaglandin D-2 Receptor, Mediates Emotional Impairment in the Lipopolysaccharide and Tumor-Induced Sickness Behavior Model, Ryota Haba,Norihito Shintani,Yusuke Onaka,Takuya Kanoh,Hyper Wang,Risa Takenaga,Atsuko Hayata,Hiroyuki Hirai,Kin-ya Nagata,Masataka Nakamura,Atsushi Kasai,Ryota Hashimoto,Kazuki Nagayasu,Takanobu Nakazawa,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 34, No. 7, p. 2514-2523, 2014/02
Examination of Calcium-Binding Protein Expression in the Inner Ear of Wild-Type, Heterozygous and Homozygous Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)-Knockout Mice in Kanamycin-Induced Ototoxicity, A. Nemeth,K. Szabadfi,B. Fulop,D. Reglodi,P. Kiss,J. Farkas,B. Szalontai,R. Gabriel,H. Hashimoto,A. Tamas, NEUROTOXICITY RESEARCH, SPRINGER, Vol. 25, No. 1, p. 57-67, 2014/01
Central PACAP mediates the sympathetic effects of leptin in a tissue-specific manner, M. Tanida,A. Hayata,N. Shintani,N. Yamamoto,Y. Kurata,T. Shibamoto,D. A. Morgan,K. Rahmouni,H. Hashimoto, Neuroscience, Vol. 238, p. 297-304, 2013/05/05
Role of Pituitary Adenylate-Cyclase Activating Polypeptide and Tac1 gene derived tachykinins in sensory, motor and vascular functions under normal and neuropathic conditions, Balint Botz,Andras Imreh,Katalin Sandor,Krisztian Elekes,Janos Szolcsanyi,Dora Reglodi,John P. Quinn,James Stewart,Andreas Zimmer,Hitoshi Hashimoto,Zsuzsanna Helyes, PEPTIDES, ELSEVIER SCIENCE INC, Vol. 43, p. 105-112, 2013/05
Distribution of Secretin Receptors in the Rat Central Nervous System: an in situ Hybridization Study, Zsuzsanna E. Toth,Andrea Heinzlmann,Hitoshi Hashimoto,Katalin Koeves, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 50, No. 1, p. 172-178, 2013/05
[Pituitary adenylate cyclase-activating polypeptide(PACAP) plays significant roles in mental function and neuronal development]., Hayata-Takano A,Seiriki K,Tajiri M,Ogata K,Shintani N,Baba A,Hashimoto H, Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, Vol. 33, No. 2, p. 73-75, 2013/04
Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice, Yukio Ago,Koji Yano,Ryota Araki,Naoki Hiramatsu,Yuki Kita,Toshiyuki Kawasaki,Hirotaka Onoe,Shigeyuki Chaki,Atsuro Nakazato,Hitoshi Hashimoto,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, Neuropharmacology, Vol. 65, p. 29-38, 2013/02
Impaired response to hypoxia in the respiratory center is a major cause of neonatal death of the PACAP-knockout mouse, Satoru Arata,Tomoya Nakamachi,Hiroshi Onimaru,Hitoshi Hashimoto,Seiji Shioda, European Journal of Neuroscience, Vol. 37, No. 3, p. 407-416, 2013/02
The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide, Yukio Ago,Naoki Hiramatsu,Toshihiro Ishihama,Keisuke Hazama,Atsuko Hayata-Takano,Yasuhiro Shibasaki,Norihito Shintani,Hitoshi Hashimoto,Toshiyuki Kawasaki,Hirotaka Onoe,Shigeyuki Chaki,Atsuro Nakazato,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, BEHAVIOURAL PHARMACOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, No. 1, p. 74-77, 2013/01
PACAP Inhibits β-cell Mass Expansion in a Mouse Model of Type II Diabetes: Persistent Suppressive Effects on Islet Density, Inoue H,Shintani N,Sakurai Y,Higashi S,Hayata-Takano A,Baba A,Hashimoto H, Front Endocrinol (Lausanne), Vol. 4, 2013
Serotonin 5-HT7 Receptor Blockade Reverses Behavioral Abnormalities in PACAP-Deficient Mice and Receptor Activation Promotes Neurite Extension in Primary Embryonic Hippocampal Neurons Therapeutic Implications for Psychiatric Disorders, Minako Tajiri,Atsuko Hayata-Takano,Kaoru Seiriki,Katsuya Ogata,Keisuke Hazama,Norihito Shintani,Akemichi Baba,Hitoshi Hashimoto, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, No. 3, p. 473-481, 2012/11
PACAP is an Endogenous Protective Factor-Insights from PACAP-Deficient Mice, D. Reglodi,P. Kiss,K. Szabadfi,T. Atlasz,R. Gabriel,G. Horvath,P. Szakaly,B. Sandor,A. Lubics,E. Laszlo,J. Farkas,A. Matkovits,R. Brubel,H. Hashimoto,A. Ferencz,A. Vincze,Z. Helyes,L. Welke,A. Lakatos,A. Tamas, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, No. 3, p. 482-492, 2012/11
Intranasal Application of Secretin, Similarly to Intracerebroventricular Administration, Influences the Motor Behavior of Mice Probably Through Specific Receptors, Andrea Heinzlmann,Gusztav Kiss,Zsuzsanna E. Toth,Roberta Dochnal,Agnes Pal,Ildiko Sipos,Mate Manczinger,Gyula Szabo,Hitoshi Hashimoto,Katalin Koeves, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, No. 3, p. 558-564, 2012/11
Effects of Pituitary Adenylate Cyclase Activating Polypeptide on Human Sperm Motility, R. Brubel,P. Kiss,A. Vincze,A. Varga,A. Varnagy,J. Bodis,L. Mark,E. Jambor,G. Maasz,H. Hashimoto,Zs. Helyes,G. Toth,A. Tamas,M. Koppan,D. Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, No. 3, p. 623-630, 2012/11
Compensatory Recovery of Blood Glucose Levels in KKA(y) Mice Fed a High-Fat Diet: Insulin-Sparing Effects of PACAP Overexpression in beta Cells, Yusuke Sakurai,Hiroaki Inoue,Norihito Shintani,Akihiro Arimori,Ken-ichi Hamagami,Atsuko Hayata-Takano,Akemichi Baba,Hitoshi Hashimoto, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, No. 3, p. 647-653, 2012/11
Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with C-11-labeled 20-HETE synthase-specific inhibitor, Toshiyuki Kawasaki,Toshiyuki Marumo,Keiko Shirakami,Tomoko Mori,Hisashi Doi,Masaaki Suzuki,Yasuyoshi Watanabe,Shigeyuki Chaki,Atsuro Nakazato,Yukio Ago,Hitoshi Hashimoto,Toshio Matsuda,Akemichi Baba,Hirotaka Onoe, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, NATURE PUBLISHING GROUP, Vol. 32, No. 9, p. 1737-1746, 2012/09
A simplified method to generate serotonergic neurons from mouse embryonic stem and induced pluripotent stem cells, Takeshi Shimada,Yoshihiro Takai,Kikuko Shinohara,Atsushi Yamasaki,Keiko Tominaga-Yoshino,Akihiko Ogura,Akihiro Toi,Kouji Asano,Norihito Shintani,Atsuko Hayata-Takano,Akemichi Baba,Hitoshi Hashimoto, JOURNAL OF NEUROCHEMISTRY, WILEY, Vol. 122, No. 1, p. 81-93, 2012/07
Comparative Examination of Inner Ear in Wild Type and Pituitary Adenylate Cyclase Activating Polypeptide (PACAP)-Deficient Mice, A. Tamas,K. Szabadfi,A. Nemeth,B. Fulop,P. Kiss,T. Atlasz,R. Gabriel,H. Hashimoto,A. Baba,N. Shintani,Zs Helyes,D. Reglodi, NEUROTOXICITY RESEARCH, SPRINGER, Vol. 21, No. 4, p. 435-444, 2012/05
Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and/or motivation in mice: Possible role of activation of the central amygdala, Ryota Haba,Norihito Shintani,Yusuke Onaka,Hyper Wang,Risa Takenaga,Atsuko Hayata,Akemichi Baba,Hitoshi Hashimoto, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 228, No. 2, p. 423-431, 2012/03
The Selective Metabotropic Glutamate 2/3 Receptor Agonist MG50028 Reverses Isolation Rearing Induced Abnormal Behaviors in Mice, Yukio Ago,Ryota Araki,Koji Yano,Toshiyuki Kawasaki,Shigeyuki Chaki,Atsuro Nakazato,Hirotaka Onoe,Hitoshi Hashimoto,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, No. 2, p. 295-298, 2012/02
THE BEHAVIORAL PHENOTYPE OF PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE-DEFICIENT MICE IN ANXIETY AND DEPRESSION TESTS IS ACCOMPANIED BY BLUNTED c-Fos EXPRESSION IN THE BED NUCLEUS OF THE STRIA TERMINALIS, CENTRAL PROJECTING EDINGER-WESTPHAL NUCLEUS, VENTRAL LATERAL SEPTUM, AND DORSAL RAPHE NUCLEUS, B. Gaszner,V. Kormos,T. Kozicz,H. Hashimoto,D. Reglodi,Z. Helyes, NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 202, p. 283-299, 2012/01
Pituitary adenylate cyclase-activating polypeptide plays a key role in nitroglycerol-induced trigeminovascular activation in mice, Adrienn Markovics,Viktoria Kormos,Balazs Gaszner,Arvin Lashgarara,Eva Szoke,Katalin Sandor,Krisztina Szabadfi,Bernadett Tuka,Janos Tajti,Janos Szolcsanyi,Erika Pinter,Hitoshi Hashimoto,Jozsef Kun,Dora Reglodi,Zsuzsanna Helyes, NEUROBIOLOGY OF DISEASE, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 45, No. 1, p. 633-644, 2012/01
Neuroprotective Effect of Endogenous Pituitary Adenylate Cyclase-Activating Polypeptide on Spinal Cord Injury, Tsuchikawa Daisuke,Nakamachi Tomoya,Tsuchida Masashi,Wada Yoshihiro,Hori Motohide,Farkas Jozsef,Yoshikawa Akira,Kagami Nobuyuki,Imai Nori,Shintani Norihito,Hashimoto Hitoshi,Atsumi Takashi,Shioda Seiji, Journal of Molecular Neuroscience, Vol. 48, No. 3, p. 508-517, 2012
Mice Deficient in Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) are More Susceptible to Retinal Ischemic Injury In Vivo, K. Szabadfi,T. Atlasz,P. Kiss,B. Danyadi,A. Tamas,Zs. Helyes,H. Hashimoto,N. Shintani,A. Baba,G. Toth,R. Gabriel,D. Reglodi, NEUROTOXICITY RESEARCH, SPRINGER, Vol. 21, No. 1, p. 41-48, 2012/01
Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice., Satoko Hattori,Keizo Takao,Koichi Tanda,Keiko Toyama,Norihito Shintani,Akemichi Baba,Hitoshi Hashimoto,Tsuyoshi Miyakawa, Frontiers in behavioral neuroscience, Vol. 6, p. 58-58, 2012
Role of endogenous pituitary adenylate cyclase activating polypeptide (PACAP) in myelination of the rodent brain: Lessons from PACAP-deficient mice, Andras Vincze,Dora Reglodi,Zsuzsanna Helyes,Hitoshi Hashimoto,Norihito Shintani,Hajnalka Abraham, INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 29, No. 8, p. 923-935, 2011/12
Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission, Yukio Ago,Ryota Araki,Koji Yano,Naoki Hiramatsu,Toshiyuki Kawasaki,Shigeyuki Chaki,Atsuro Nakazato,Hirotaka Onoe,Hitoshi Hashimoto,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, PSYCHOPHARMACOLOGY, SPRINGER, Vol. 217, No. 3, p. 443-452, 2011/10
Pituitary adenylate cyclase-activating polypeptide plays an anti-inflammatory role in endotoxin-induced airway inflammation: In vivo study with gene-deleted mice, Krisztian Elekes,Katalin Sandor,Andras Moricz,Laszlo Kereskai,Agnes Kemeny,Eva Szoke,Aniko Perkecz,Dora Reglodi,Hitoshi Hashimoto,Erika Pinter,Janos Szolcsanyi,Zsuzsanna Helyes, PEPTIDES, ELSEVIER SCIENCE INC, Vol. 32, No. 7, p. 1439-1446, 2011/07
PACAP centrally mediates emotional stress-induced corticosterone responses in mice, Naohiro Tsukiyama,Yoko Saida,Michiya Kakuda,Norihito Shintani,Atsuko Hayata,Yoshiko Morita,Mamoru Tanida,Minako Tajiri,Keisuke Hazama,Katsuya Ogata,Hitoshi Hashimoto,Akemichi Baba, STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS, INFORMA HEALTHCARE, Vol. 14, No. 4, p. 368-375, 2011/07
The melanocortin system is involved in regulating autonomic nerve activity through central pituitary adenylate cyclase-activating polypeptide, Mamoru Tanida,Norihito Shintani,Hitoshi Hashimoto, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 70, No. 1, p. 55-61, 2011/05
PACAP is Implicated in the Stress Axes, Hitoshi Hashimoto,Norihito Shintani,Mamoru Tanida,Atsuko Hayata,Ryota Hashimoto,Akemichi Baba, CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBL LTD, Vol. 17, No. 10, p. 985-989, 2011/04
Mice deficient in pituitary adenylate cyclase activating polypeptide (PACAP) show increased susceptibility to in vivo renal ischemia/reperfusion injury, Peter Szakaly,Eszter Laszlo,Krisztina Kovacs,Boglarka Racz,Gabriella Horvath,Andrea Ferencz,Andrea Lubics,Peter Kiss,Andrea Tamas,Reka Brubel,Balazs Opper,Akemichi Baba,Hitoshi Hashimoto,Jozsef Farkas,Attila Matkovits,Tamas Magyarlaki,Zsuzsanna Helyes,Dora Reglodi, NEUROPEPTIDES, CHURCHILL LIVINGSTONE, Vol. 45, No. 2, p. 113-121, 2011/04
[Translational research for mental disorder -schizophrenia]., Hashimoto R,Yasuda Y,Ohi K,Fukumoto M,Yamamori H,Shintani N,Hashimoto H,Baba A,Takeda M, Nippon yakurigaku zasshi. Folia pharmacologica Japonica, 2, Vol. 137, No. 2, p. 79-82, 2011/02
Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice, Toshiyuki Kawasaki,Yukio Ago,Koji Yano,Ryota Araki,Yusuke Washida,Hirotaka Onoe,Shigeyuki Chaki,Atsuro Nakazato,Hitoshi Hashimoto,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, NEUROPHARMACOLOGY, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 60, No. 2-3, p. 397-404, 2011/02
Trophic Effects of PACAP on Pancreatic Islets: A Mini-Review, Yusuke Sakurai,Norihito Shintani,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 43, No. 1, p. 3-7, 2011/01
ROLE OF ENDOGENOUS PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE IN ADULT HIPPOCAMPAL NEUROGENESIS, Y. Ago,M. Yoneyama,T. Ishihama,S. Kataoka,K. Kawada,T. Tanaka,K. Ogita,N. Shintani,H. Hashimoto,A. Baba,K. Takuma,T. Matsuda, NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 172, p. 554-561, 2011/01
Neuroprotective Effect of PACAP Against NMDA-Induced Retinal Damage in the Mouse, Kimi Endo,Tomoya Nakamachi,Tamotsu Seki,Nobuyuki Kagami,Yoshihiro Wada,Keisuke Nakamura,Koji Kishimoto,Motohide Hori,Daisuke Tsuchikawa,Norihito Shinntani,Hitoshi Hashimoto,Akemichi Baba,Ryohei Koide,Seiji Shioda, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 43, No. 1, p. 22-29, 2011/01
Cerulein-Induced Acute Pancreatitis in PACAP Knockout Mice, Yusuke Sakurai,Norihito Shintani,Akihiro Arimori,Ken-ichi Hamagami,Naoko Higuchi,Hiroaki Inoue,Kazuya Ikeda,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 43, No. 1, p. 8-15, 2011/01
Effect of PACAP on tear secretion in mouse, Nakamachi Tomoya,Aizawa Youichi,Ohtaki Hirokazu,Yofu Sachiko,Seki Tamotsu,Endo Kimi,Nakamura Keisuke,Nobuyuki Kagami,Arata Satoru,Shintani Norihito,Hashimoto Hitoshi,Baba Akemichi,Shioda Seiji, JOURNAL OF MOLECULAR NEUROSCIENCE, Vol. 42, No. 3, 2010/11
Endogenous PACAP attenuated doxorubicin-induced myocardial damage, Mori Hiroyoshi,Nakamachi Tomoya,Ohtaki Hirokazu,Hasegawa Fumio,Yofu Sachiko,Suzuki Hiroshi,Takeyama Youichi,Shintani Norihito,Hashimoto Hitoshi,Baba Akemichi,Shioda Seiji, JOURNAL OF MOLECULAR NEUROSCIENCE, Vol. 42, No. 3, 2010/11
Suppression of oxidative stress by PACAP, Sato Atsushi,Ohtaki Hirokazu,Dohi Kenji,Nakamachi Tomoya,Yofu Sachiko,Ohara Kenji,Hashimoto Hitoshi,Murakami Tomoe,Ando Miki,Shintani Norihito,Baba Akemichi,Shioda Seiji, JOURNAL OF MOLECULAR NEUROSCIENCE, Vol. 42, No. 3, 2010/11
Regulation of oxidative stress by pituitary adenylate cyclase-activating polypeptide (PACAP) mediated by PACAP receptor., Hirokazu Ohtaki,Atsushi Satoh,Tomoya Nakamachi,Sachiko Yofu,Kenji Dohi,Hiroyoshi Mori,Kenji Ohara,Kazuyuki Miyamoto,Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Masaji Matsunaga,Seiji Shioda, Journal of molecular neuroscience : MN, Vol. 42, No. 3, p. 397-403, 2010/11
Presence of Endogenous PACAP-38 Ameliorated Intestinal Cold Preservation Tissue Injury, Andrea Ferencz,Gyorgy Weber,Zsuzsanna Helyes,Hitoshi Hashimoto,Akemichi Baba,Dora Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 428-434, 2010/11
Pituitary Adenylate Cyclase-Activating Polypeptide Deficiency Enhances Oxazolone-Induced Allergic Contact Dermatitis in Mice, Agnes Kemeny,Dora Reglodi,Renata Cseharovszky,Hitoshi Hashimoto,Akemichi Baba,Janos Szolcsanyi,Erika Pinter,Zsuzsanna Helyes, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 443-449, 2010/11
Intra-Islet PACAP Protects Pancreatic beta-Cells Against Glucotoxicity and Lipotoxicity, Masanori Nakata,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Toshihiko Yada, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 404-410, 2010/11
Impaired nocifensive behaviours and mechanical hyperalgesia, but enhanced thermal allodynia in pituitary adenylate cyclase-activating polypeptide deficient mice, K. Sandor,V. Kormos,B. Botz,A. Imreh,K. Boelcskei,B. Gaszner,A. Markovics,J. Szolcsanyi,N. Shintani,H. Hashimoto,A. Baba,D. Reglodi,Zs Helyes, NEUROPEPTIDES, CHURCHILL LIVINGSTONE, Vol. 44, No. 5, p. 363-371, 2010/10
GnRH-induced PACAP and PAC1 receptor expression in pituitary gonadotrophs: A possible role in the regulation of gonadotropin subunit gene expression, Indri N. Purwana,Haruhiko Kanasaki,Aki Oride,Tselmeg Mijiddorj,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Kohji Miyazaki, PEPTIDES, ELSEVIER SCIENCE INC, Vol. 31, No. 9, p. 1748-1755, 2010/09
Mice Deficient in Neuropeptide PACAP Demonstrate Increased Sensitivity to In Vitro Kidney Hypoxia, G. Horvath,B. Racz,P. Szakaly,P. Kiss,E. Laszlo,L. Hau,A. Tamas,Z. Helyes,A. Lubics,H. Hashimoto,A. Baba,D. Reglodi, TRANSPLANTATION PROCEEDINGS, ELSEVIER SCIENCE INC, Vol. 42, No. 6, p. 2293-2295, 2010/07
Comparison of Intestinal Cold Preservation Injury on Pituitary Adenylate Cyclase-Activating Polypeptide in Knockout and Wild-Type Mice, A. Ferencz,K. Nedvig,T. Fekecs,B. Racz,G. Weber,H. Hashimoto,A. Baba,Z. Helyes,D. Regloedi, TRANSPLANTATION PROCEEDINGS, ELSEVIER SCIENCE INC, Vol. 42, No. 6, p. 2290-2292, 2010/07
Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice, Toshihiro Ishihama,Yukio Ago,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, BEHAVIOURAL BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 209, No. 2, p. 274-280, 2010/06
Cardioprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on Doxorubicin-induced cardiomyopathy in mice., Hiroyoshi Mori,Tomoya Nakamachi,Hirokazu Ohtaki,Sachiko Yofu,Atsushi Sato,Kimi Endo,Yoshitaka Iso,Hiroshi Suzuki,Youichi Takeyama,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Seiji Shioda, Circulation journal : official journal of the Japanese Circulation Society, Vol. 74, No. 6, p. 1183-90, 2010/06
15d-Prostaglandin J(2) Enhancement of Nerve Growth Factor-Induced Neurite Outgrowth Is Blocked by the Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type 2 Cells (CRTH2) Antagonist CAY10471 in PC12 Cells, Michiyoshi Hatanaka,Norihiro Shibata,Norihito Shintani,Ryota Haba,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 113, No. 1, p. 89-93, 2010/05
Regulation of autonomic nerve activities by central pituitary adenylate cyclase-activating polypeptide, Mamoru Tanida,Norihito Shintani,Yoshiko Morita,Naohiro Tsukiyama,Michiyoshi Hatanaka,Hitoshi Hashimoto,Hajime Sawai,Akemichi Baba,Katsuya Nagai, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 161, No. 1-3, p. 73-80, 2010/04
PACAP-Deficient Mice Exhibit Light Parameter-Dependent Abnormalities on Nonvisual Photoreception and Early Activity Onset, Chihiro Kawaguchi,Yasushi Isojima,Norihito Shintani,Michiyoshi Hatanaka,Xiaohong Guo,Nobuaki Okumura,Katsuya Nagai,Hitoshi Hashimoto,Akemichi Baba, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 5, No. 2, 2010/02
Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder, Ryota Hashimoto,Hitoshi Hashimoto,Norihito Shintani,Kazutaka Ohi,Hiroaki Hori,Osamu Saitoh,Asako Kosuga,Masahiko Tatsumi,Nakao Iwata,Norio Ozaki,Kunitoshi Kamijima,Akemichi Baba,Masatoshi Takeda,Hiroshi Kunugi, NEUROSCIENCE LETTERS, ELSEVIER IRELAND LTD, Vol. 468, No. 3, p. 300-302, 2010/01
Mice deficient in pituitary adenylate cyclase activating polypeptide display increased sensitivity to renal oxidative stress in vitro, Gabriella Horvath,Laszlo Mark,Reka Brubel,Peter Szakaly,Boglarka Racz,Peter Kiss,Andrea Tamas,Zsuzsanna Helyes,Andrea Lubics,Hitoshi Hashimoto,Akemichi Baba,Norihito Shintani,Gergely Furjes,Jozsef Nemeth,Dora Reglodi, NEUROSCIENCE LETTERS, ELSEVIER IRELAND LTD, Vol. 469, No. 1, p. 70-74, 2010/01
Increased Stathmin1 Expression in the Dentate Gyrus of Mice Causes Abnormal Axonal Arborizations, Kohei Yamada,Shinsuke Matsuzaki,Tsuyoshi Hattori,Ryusuke Kuwahara,Manabu Taniguchi,Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Natsuko Kumamoto,Kazuo Yamada,Takeo Yoshikawa,Taiichi Katayama,Masaya Tohyama, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 5, No. 1, 2010/01
Increased ethanol preference and serotonin 1A receptor-dependent attenuation of ethanol-induced hypothermia in PACAP-deficient mice, Kazuhiro Tanaka,Akiko Kunishige-Yamamoto,Hitoshi Hashimoto,Norihito Shintani,Atsuko Hayata,Akemichi Baba, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 391, No. 1, p. 773-777, 2010/01
Endogenous pituitary adenylate cyclase activating polypeptide is involved in suppression of edema in the ischemic brain., Tomoya Nakamachi,Hirokazu Ohtaki,Sachiko Yofu,Kenji Dohi,Jun Watanabe,Hiroyoshi Mori,Atsushi Sato,Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Seiji Shioda, Acta neurochirurgica. Supplement, Vol. 106, p. 43-6, 2010
Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery, David Vaudry,Anthony Falluel-Morel,Steve Bourgault,Magali Basille,Delphine Burel,Olivier Wurtz,Alain Fournier,Billy K. C. Chow,Hitoshi Hashimoto,Ludovic Galas,Hubert Vaudry, PHARMACOLOGICAL REVIEWS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 61, No. 3, p. 283-357, 2009/09
Over-Expression of Pancreatic Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Aggravates Cerulein-Induced Acute Pancreatitis in Mice, Ken-ichi Hamagami,Yusuke Sakurai,Norihito Shintani,Naoko Higuchi,Kazuya Ikeda,Hitoshi Hashimoto,Akinobu Suzuki,Hiroshi Kiyama,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 110, No. 4, p. 451-458, 2009/08
Depression-like behavior in the forced swimming test in PACAP-deficient mice: amelioration by the atypical antipsychotic risperidone, Hitoshi Hashimoto,Ryota Hashimoto,Norihito Shintani,Kazuhiro Tanaka,Akiko Yamamoto,Michiyoshi Hatanaka,Xiaohong Guo,Yoshiko Morita,Mamoru Tanida,Katsuya Nagai,Masatoshi Takeda,Akemichi Baba, JOURNAL OF NEUROCHEMISTRY, WILEY, Vol. 110, No. 2, p. 595-602, 2009/07
Inhibitory Effects of Osemozotan, a Serotonin 1A-Receptor Agonist, on Methamphetamine-Induced c-Fos Expression in Prefrontal Cortical Neurons, Rie Tsuchida,Masahiro Kubo,Norihito Shintani,Michikazu Abe,Katalin Koves,Kazuki Uetsuki,Mariko Kuroda,Hitoshi Hashimoto,Akemichi Baba, BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, Vol. 32, No. 4, p. 728-731, 2009/04
An Antihyperkinetic Action by the Serotonin 1A-Receptor Agonist Osemozotan Co-administered With Psychostimulants or the Non-stimulant Atomoxetine in Mice, Rie Tsuchida,Masahiro Kubo,Mariko Kuroda,Yasuhiro Shibasaki,Norihito Shintani,Michikazu Abe,Katalin Koves,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 109, No. 3, p. 396-402, 2009/03
Retardation of retinal vascular development in apelin-deficient mice, Atsushi Kasai,Norihito Shintani,Hideaki Kato,Satoshi Matsuda,Fumi Gomi,Ryota Haba,Hitoshi Hashimoto,Michiya Kakuda,Yasuo Tano,Akemichi Baba, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 28, No. 10, p. 1717-1722, 2008/10
Lack of light-induced elevation of renal sympathetic nerve activity and plasma corticosterone levels in PACAP-deficient mice, Michiyoshi Hatanaka,Mamoru Tanida,Norihito Shintani,Yasushi Isojima,Chihiro Kawaguchi,Hitoshi Hashimoto,Michiya Kakuda,Ryota Haba,Katsuya Nagai,Akemichi Baba, NEUROSCIENCE LETTERS, ELSEVIER IRELAND LTD, Vol. 444, No. 2, p. 153-156, 2008/10
Involvements of PHI-nitric oxide and PACAP-BK channel in the sustained relaxation of mouse gastric fundus, Kiyomi Hagi,Yasu-Taka Azuma,Hidemitsu Nakajima,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Tadayoshi Takeuchi, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 590, No. 1-3, p. 80-86, 2008/08
PACAP provides colonic protection against dextran sodium sulfate induced colitis, Yasu-Taka Azuma,Kiycimi Hagi,Norihito Shintani,Mitsuru Kuwamura,Hidemitsu Nakajima,Hitoshi Hashimoto,Akemichi Baba,Tadaycishi Takeuchi, JOURNAL OF CELLULAR PHYSIOLOGY, WILEY-LISS, Vol. 216, No. 1, p. 111-119, 2008/07
Markedly reduced white adipose tissue and increased insulin sensitivity in Adcyap1-deficient mice, Shuhei Tomimoto,Tatsuya Qjika,Norihito Shintani,Hitoshi Hashimoto,Ken-ichi Hamagami,Kazuya Ikeda,Masanori Nakata,Toshihiko Yada,Yusuke Sakurai,Takeshi Shimada,Yoshiko Morita,Chie Ishida,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 107, No. 1, p. 41-48, 2008/05
PACAP is transiently expressed in anterior pituitary gland of rats: In situ hybridization and cell immunoblot assay studies, Andrea Heinzlmann,Eszter Kirilly,Kinga Meltzer,Eniko Szabo,Akemichi Baba,Hitoshi Hashimoto,Katalin Koeves, PEPTIDES, ELSEVIER SCIENCE INC, Vol. 29, No. 4, p. 571-577, 2008/04
Galantamine and donepezil differently affect isolation rearing-induced deficits of prepulse inhibition in mice, Ken Koda,Yukio Ago,Toshiyuki Kawasaki,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, PSYCHOPHARMACOLOGY, SPRINGER, Vol. 196, No. 2, p. 293-301, 2008/02
Research to develop therapy for ischemic disease from basic research to translational research, Atsushi Kasai,Norihito Shintani,Hideaki Kato,Michiya Kakuda,Fumi Gomi,Yasuo Tano,Hitoshi Hashimoto,Sadaaki Maeda,Akemichi Baba, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, PHARMACEUTICAL SOC JAPAN, Vol. 128, p. 45-48, 2008
Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia, R. Hashimoto,H. Hashimoto,N. Shintani,S. Chiba,S. Hattori,T. Okada,M. Nakajima,K. Tanaka,N. Kawagishi,K. Nemoto,T. Mori,T. Ohnishi,H. Noguchi,H. Hori,T. Suzuki,N. Iwata,N. Ozaki,T. Nakabayashi,O. Saitoh,A. Kosuga,M. Tatsumi,K. Kamijima,D. R. Weinberger,H. Kunugi,A. Baba, MOLECULAR PSYCHIATRY, NATURE PUBLISHING GROUP, Vol. 12, No. 11, p. 1026-1032, 2007/11
Ritanserin reverses repeated methamphetamine-induced behavioral and neurochemical sensitization in mice, Yukio Ago,Shigeo Nakamura,Naoko Kajita,Misato Uda,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, SYNAPSE, WILEY-LISS, Vol. 61, No. 9, p. 757-763, 2007/09
Methamphetamine-induced hyperactivity and behavioral sensitization in PACAP deficient mice, Harumi Fujii,Toshihiro Ishihama,Yukio Ago,Norihito Shintani,Michiya Kakuda,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, PEPTIDES, ELSEVIER SCIENCE INC, Vol. 28, No. 9, p. 1674-1679, 2007/09
Anxiety-like and exploratory behaviors of isolation-reared mice in the staircase test, Yukio Ago,Keiko Takahashi,Shigeo Nakamura,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 104, No. 2, p. 153-158, 2007/06
A novel DISC1-interacting partner DISC1-binding zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth, T. Hattori,K. Baba,S. Matsuzaki,A. Honda,K. Miyoshi,K. Inoue,M. Taniguchi,H. Hashimoto,N. Shintani,A. Baba,S. Shimizu,F. Yukioka,N. Kumamoto,A. Yamaguchi,M. Tohyama,T. Katayama, MOLECULAR PSYCHIATRY, NATURE PUBLISHING GROUP, Vol. 12, No. 4, p. 398-407, 2007/04
Galantamine increases the extracellular acetylcholine levels in mouse cerebral cortex., Ken Koda,Koji Yano,Yukio Ago,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, PHARMACEUTICAL SOC JAPAN, Vol. 127, p. 141-143, 2007
Neuroprotective mechanism of PACAP associated with IL-6 signaling, Nakamachi Tomoya,Ohtaki Hirokazu,Dohi Kenji,Yofu Sachiko,Hashimoto Hitoshi,Shintani Norihito,Baba Akemichi,Arimura Akira,Shioda Seiji, JOURNAL OF MOLECULAR NEUROSCIENCE, Vol. 33, No. 3, p. 346-347, 2007
Modification of cocaine-induced behavioral and neurochemical effects by serotonin(1A) receptor agonist/antagonist in mice, Shigeo Nakamura,Yukio Ago,Aiko Hayashi,Soichi Itoh,Michrya Kakuda,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, SYNAPSE, WILEY-LISS, Vol. 60, No. 7, p. 479-484, 2006/12
PACAP suppresses an ischemic neuronal damage mediating in IL-6 signalling, Nakamachi Tomoya,Ohtaki Hirokazu,Dohi Kenji,Yofu Sachiko,Hodoyama Kei,Hashimoto Hitoshi,Shintani Norihito,Baba Akemichi,Arimura Akira,Shioda Seiji, REGULATORY PEPTIDES, Vol. 135, No. 3, 2006/08/30
Endogenous PACAP acts as a neuroprotectant against ischemic neuronal damage mediating bcl-2 signal, Nakamachi Tomoya,Ohtaki Hirokazu,Dohi Kenji,Hodoyama Kei,Yofu Sachiko,Hashimoto Hitoshi,Shintani Norihito,Baba Akemichi,Arimura Akira,Shioda Seiji, FRONTIERS IN NEUROENDOCRINOLOGY, Vol. 27, No. 1, 2006/05
Psychostimulant-induced attenuation of hyperactivity and prepulse inhibition deficits in Adcyap1-deficient mice, K Tanaka,N Shintani,H Hashimoto,N Kawagishi,Y Ago,T Matsuda,R Hashimoto,H Kunugi,A Yamamoto,C Kawaguchi,T Shimada,A Baba, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 26, No. 19, p. 5091-5097, 2006/05
Serotonergic inhibition of intense jumping behavior in mice lacking PACAP (Adeyap1(-vertical bar-)), Norihito Shintani,Hitoshi Hashimoto,Kazuhiro Tanaka,Naofumi Kawagishi,Chihiro Kawaguchi,Michiyoshi Hatanaka,Yukio Ago,Toshio Matsuda,Akemichi Baba, VIP, PACAP, AND RELATED PEPTIDES: FROM GENE TO THERAPY, BLACKWELL PUBLISHING, Vol. 1070, p. 545-549, 2006
Roles of PACAP and PHI as inhibitory neurotransmitters in the circular muscle of mouse antrum, M Toyoshima,T Takeuchi,H Goto,K Mukai,N Shintani,H Hashimoto,A Baba,F Hata, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, SPRINGER, Vol. 451, No. 4, p. 559-568, 2006/01
Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6, OHTAKI H,NAKAMACHI T,DOHI K,AIZAWA Y,TAKAKI A,HODOYAMA K,YOFU S,HASHIMOTO H,SHINTANI N,BABA A,KOPF M,IWAKURA Y,MATSUDA K,ARIMURA A,SHIODA S, Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 19, p. 7488-7493, 2006
PACAP- and PHI-mediated sustained relaxation in circular muscle of gastric fundus: Findings obtained in PACAP knockout mice, K Mukai,T Takeuchi,M Toyoshima,Y Satoh,A Fujita,N Shintani,H Hashimoto,A Baba,F Hata, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 133, No. 1-3, p. 54-61, 2006/01
New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice, Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba, VIP, PACAP, AND RELATED PEPTIDES: FROM GENE TO THERAPY, BLACKWELL PUBLISHING, Vol. 1070, p. 75-89, 2006
Lack of trimethyltin (TMT)-induced elevation of plasma corticosterone in PACAP-deficient mice, Yoshiko Morita,Daisuke Yanagida,Norihito Shintani,Kiyokazu Ogita,Norito Nishiyama,Rie Tsuchida,Hitoshi Hashimoto,Akemichi Baba, VIP, PACAP, AND RELATED PEPTIDES: FROM GENE TO THERAPY, BLACKWELL PUBLISHING, Vol. 1070, p. 450-456, 2006
Inhibition of self-renewal and induction of neural differentiation by PACAP in neural progenitor cells, Megumi Hirose,Hitoshi Hashimoto,Junkko Iga,Norihito Shintani,Megumi Nakanishi,Naohisa Arakawa,Takeshi Shimada,Akemichi Baba, VIP, PACAP, AND RELATED PEPTIDES: FROM GENE TO THERAPY, BLACKWELL PUBLISHING, Vol. 1070, p. 342-347, 2006
Monoaminergic neuronal development is not affected in PACAP-gene-deficient mice., Tetsuo Ogawa,Tomoya Nakamachi,Hirokazu Ohtaki,Hitoshi Hashimoto,Shintani N,Akemichi Baba,Jun Watanabe,Sakae Kikuyama,Seiji Shioda, Regulatory peptides, Vol. 126, No. 1-2, p. 103-8, 2005/03/15
Neuroprotective action of endogenous PACAP in cultured rat cortical neurons, N Shintani,S Suetake,H Hashimoto,K Koga,A Kasai,C Kawaguchi,Y Morita,M Hirose,Y Sakai,S Tomimoto,T Matsuda,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 126, No. 1-2, p. 123-128, 2005/03
Differential expression of mRNAs for PACAP and its receptors during neural differentiation of embryonic stem cells, M Hirose,H Hashimoto,N Shintani,M Nakanishi,N Arakawa,J Iga,H Niwa,J Miyazaki,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 126, No. 1-2, p. 109-113, 2005/03
Reduced hypothermic and hypnotic responses to ethanol in PACAP-deficient mice, K Tanaka,H Hashimoto,N Shintani,A Yamamoto,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 123, No. 1-3, p. 95-98, 2004/12
Overexpression of PACAP in the pancreas failed to rescue early postnatal mortality in PACAP-null mice, N Shintani,H Hashimoto,K Tanaka,C Kawaguchi,S Tomimoto,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 123, No. 1-3, p. 155-159, 2004/12
Apelin is a novel angiogenic factor in retinal endothelial cells, A Kasai,N Shintani,M Oda,M Kakuda,H Hashimoto,T Matsuda,S Hinuma,A Baba, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 325, No. 2, p. 395-400, 2004/12
PACAP deficient mice display reduced carbohydrate intake and PACAP activates NPY-containing neurons in the rat hypothalamic arcuate nucleus, M Nakata,D Kohno,N Shintani,Y Nemoto,H Hashimoto,A Baba,T Yada, NEUROSCIENCE LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 370, No. 2-3, p. 252-256, 2004/11
PACAPの摂食調節作用, 中田正範,河野大輔,新谷紀人,橋本均,馬場明道,矢田俊彦, 肥満研究, (一社)日本肥満学会, Vol. 10, No. Suppl., p. 115-115, 2004/09
Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain, T Mabuchi,N Shintani,S Matsumura,E Okuda-Ashitaka,H Hashimoto,T Muratani,T Minami,A Baba,S Ito, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 24, No. 33, p. 7283-7291, 2004/08
Overexpression of pituitary adenylate cyclase-activating polypeptide in islets inhibits hyperinsulinemia and islet hyperplasia in agouti yellow mice, S Tomimoto,H Hashimoto,N Shintani,K Yamamoto,Y Kawabata,KI Hamagami,K Yamagata,JI Miyagawa,A Baba, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 309, No. 2, p. 796-803, 2004/05
PACAP activates Rac1 and synergizes with NGF to activate ERK1/2, thereby inducing neurite outgrowth in PC12 cells, Y Sakai,H Hashimoto,N Shintani,H Katoh,M Negishi,C Kawaguchi,A Kasai,A Baba, MOLECULAR BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 123, No. 1-2, p. 18-26, 2004/04
The pituitary adenylate cyclase-activating polypeptide is a physiological inhibitor of platelet activation, K Freson,H Hashimoto,C Thys,C Wittevrongel,S Danloy,Y Morita,N Shintani,Y Tomiyama,J Vermylen,MF Hoylaerts,A Baba,C Van Geet, JOURNAL OF CLINICAL INVESTIGATION, AMER SOC CLINICAL INVESTIGATION INC, Vol. 113, No. 6, p. 905-912, 2004/03
Pituitary adenylate cyclase-activating polypeptide does not colocalize with vasoactive intestinal polypeptide in the hypothalamic magnocellular nuclei and posterior pituitary of cats and rats, Vereczki, V,K Koves,ZE Toth,A Baba,H Hashimoto,K Fogel,A Arimura,M Kausz, ENDOCRINE, HUMANA PRESS INC, Vol. 22, No. 3, p. 225-237, 2003/12
Functional roles of the neuropeptide PACAP in brain and pancreas, N Shintani,S Tomimoto,H Hashimoto,C Kawaguchi,A Baba, LIFE SCIENCES, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 74, No. 2-3, p. 337-343, 2003/12
Possible involvement of a cyclic AMP-dependent mechanism in PACAP-induced proliferation and ERK activation in astrocytes, H Hashimoto,A Kunugi,N Arakawa,N Shintani,T Fujita,A Kasai,C Kawaguchi,Y Morita,M Hirose,Y Sakai,A Baba, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 311, No. 2, p. 337-343, 2003/11
Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate cyclase-activating polypeptide (PACAP) or PACAP type 1 receptor-mutant mice, S Matsuyama,A Matsumoto,H Hashimoto,N Shintani,A Baba, NEUROREPORT, LIPPINCOTT WILLIAMS & WILKINS, Vol. 14, No. 16, p. 2095-2098, 2003/11
Changes in light-induced phase shift of circadian rhythm in mice lacking PACAP, C Kawaguchi,K Tanaka,Y Isojima,N Shintani,H Hashimoto,A Baba,K Nagai, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 310, No. 1, p. 169-175, 2003/10
Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes, K Yamamoto,H Hashimoto,S Tomimoto,N Shintani,J Miyazaki,F Tashiro,H Aihara,T Nammo,M Li,K Yamagata,J Miyagawa,Y Matsuzawa,Y Kawabata,Y Fukuyama,K Koga,W Mori,K Tanaka,T Matsuda,A Baba, DIABETES, AMER DIABETES ASSOC, Vol. 52, No. 5, p. 1155-1162, 2003/05
Involvement of intracellular Ca2+ elevation but not cyclic AMP in PACAP-induced p38 MAP kinase activation in PC12 cells, Y Sakai,H Hashimoto,N Shintani,A Ichibori,S Tomimoto,K Tanaka,M Hirose,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 109, No. 1-3, p. 149-153, 2002/11
Defects in reproductive functions in PACAP-deficient female mice, N Shintani,W Mori,H Hashimoto,M Imai,K Tanaka,S Tomimoto,M Hirose,C Kawaguchi,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 109, No. 1-3, p. 45-48, 2002/11
PAC1 receptor-mediated relaxation of longitudinal muscle of the mouse proximal colon, K Mukai,Y Satoh,A Fujita,T Takeuchi,N Shintani,H Hashimoto,A Baba,F Hata, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 90, No. 1, p. 97-100, 2002/09
Higher brain functions of PACAP and a homologous Drosophila memory gene amnesiac: insights from knockouts and mutants, H Hashimoto,N Shintani,A Baba, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 297, No. 3, p. 427-432, 2002/09
Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP), H Hashimoto,N Shintani,K Tanaka,W Mori,M Hirose,T Matsuda,M Sakaue,J Miyazaki,H Niwa,F Tashiro,K Yamamoto,K Koga,S Tomimoto,A Kunugi,S Suetake,A Baba, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 98, No. 23, p. 13355-13360, 2001/11
Involvement of p38 MAP kinase pathway in the synergistic activation of PACAP mRNA expression by NGF and PACAP in PC12h cells, Y Sakai,H Hashimoto,N Shintani,S Tomimoto,K Tanaka,A Ichibori,M Hirose,A Baba, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 285, No. 3, p. 656-661, 2001/07
KB-R7943 inhibits store-operated Ca2+ entry in cultured neurons and astrocytes, N Arakawa,M Sakaue,Yokoyama, I,H Hashimoto,Y Koyama,A Baba,T Matsuda, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 279, No. 2, p. 354-357, 2000/12
Desensitization, surface expression, and glycosylation of a functional, epitope-tagged type IPACAP (PAC(1)) receptor, N Shintani,H Hashimoto,A Kunugi,Y Koyama,K Yamamoto,S Tomimoto,W Mori,T Matsuda,A Baba, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ELSEVIER SCIENCE BV, Vol. 1509, No. 1-2, p. 195-202, 2000/12
Mice with markedly reduced PACAP (PAC(1)) receptor expression by targeted deletion of the signal peptide, H Hashimoto,N Shintani,A Nishino,M Okabe,M Ikawa,S Matsuyama,K Itoh,K Yamamoto,S Tomimoto,T Fujita,N Hagihara,W Mori,Y Koyama,T Matsuda,S Nagata,A Baba, JOURNAL OF NEUROCHEMISTRY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 75, No. 5, p. 1810-1817, 2000/11
Na+-Ca2+ exchanger isoforms in rat neuronal preparations: different changes in their expression during postnatal development, M Sakaue,H Nakamura,Kaneko, I,Y Kawasaki,N Arakawa,H Hashimoto,Y Koyama,A Baba,T Matsuda, BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 881, No. 2, p. 212-216, 2000/10
Serum-deprivation induces cell death of rat cultured microglia accompanied with expression of Bax protein, Y Koyama,Y Kimura,Y Yoshioka,D Wakamatsu,RH Kozaki,H Hashimoto,T Matsuda,A Baba, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 83, No. 4, p. 351-354, 2000/08
Postsynaptic 5-hydroxytryptamine(1A) receptor activation increases in vivo dopamine release in rat prefrontal cortex, M Sakaue,P Somboonthum,B Nishihara,Y Koyama,H Hashimoto,A Baba,T Matsuda, BRITISH JOURNAL OF PHARMACOLOGY, STOCKTON PRESS, Vol. 129, No. 5, p. 1028-1034, 2000/03
L-lactate inhibits L-cystine/L-glutamate exchange transport and decreases glutathione content in rat cultured astrocytes, Y Koyama,Y Kimura,H Hashimoto,T Matsuda,A Baba, JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, Vol. 59, No. 5, p. 685-691, 2000/03
Transient treatments with L-glutamate and threo-beta-hydroxyaspartate induce swelling of rat cultured astrocytes, Y Koyama,T Ishibashi,T Okamoto,T Matsuda,H Hashimoto,A Baba, NEUROCHEMISTRY INTERNATIONAL, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 36, No. 2, p. 167-173, 2000/02
Synergistic induction of pituitary adenylate cyclase-activating polypeptide (PACAP) gene expression by nerve growth factor and PACAP in PC12 cells, H Hashimoto,N Hagihara,K Koga,K Yamamoto,N Shintani,S Tomimoto,W Mori,Y Koyama,T Matsuda,A Baba, JOURNAL OF NEUROCHEMISTRY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 74, No. 2, p. 501-507, 2000/02
Generation and pharmacological analysis of PAC1 receptor and PACAP knockout mice, Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Toshio Matsucla, Folia Pharmacologica Japonica, Vol. 116, p. 116-120, 2000
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components, Y Koyama,Y Yoshioka,H Hashimoto,T Matsuda,A Baba, NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 101, No. 1, p. 219-227, 2000
Endothelins stimulate expression of cyclooxygenase 2 in rat cultured astrocytes, Y Koyama,T Mizobata,N Yamamoto,H Hashimoto,T Matsuda,A Baba, JOURNAL OF NEUROCHEMISTRY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 73, No. 3, p. 1004-1011, 1999/09
Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1(VPAC(1)) receptor, H Hashimoto,A Nishino,N Shintani,N Hagihara,NG Copeland,NA Jenkins,K Yamamoto,T Matsuda,T Ishihara,S Nagata,A Baba, GENOMICS, ACADEMIC PRESS INC, Vol. 58, No. 1, p. 90-93, 1999/05
Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene, K Yamamoto,H Hashimoto,N Hagihara,A Nishino,T Fujita,T Matsuda,A Baba, GENE, ELSEVIER SCIENCE BV, Vol. 211, No. 1, p. 63-69, 1998/04
Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes, R Hosoi,T Matsuda,S Asano,H Nakamura,H Hashimoto,K Takuma,A Baba, JOURNAL OF NEUROCHEMISTRY, LIPPINCOTT-RAVEN PUBL, Vol. 69, No. 5, p. 2189-2196, 1997/11
Pituitary adenylate cyclase-activating polypeptide (PACAP) receptor mRNA in the rat adrenal gland: Localization by in situ hybridization and identification of splice variants, H Nogi,H Hashimoto,T Fujita,N Hagihara,T Matsuda,A Baba, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 75, No. 2, p. 203-207, 1997/10
Vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide receptor chimeras reveal domains that determine specificity of vasoactive intestinal polypeptide binding and activation, H Hashimoto,N Ogawa,N Hagihara,K Yamamoto,K Imanishi,H Nogi,A Nishino,T Fujita,T Matsuda,S Nagata,A Baba, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 52, No. 1, p. 128-135, 1997/07
Distribution of mRNAs for pituitary adenylate cyclase-activating polypeptide (PACAP), PACAP receptor, vasoactive intestinal polypeptide (VIP), and VIP receptors in the rat superior cervical ganglion, H Nogi,H Hashimoto,N Hagihara,S Shimada,K Yamamoto,T Matsuda,M Tohyama,A Baba, NEUROSCIENCE LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 227, No. 1, p. 37-40, 1997/05
Role of Na+-Ca2+ exchanger in agonist-induced Ca2+ signaling in cultured rat astrocytes, K Takuma,T Matsuda,H Hashimoto,J Kitanaka,S Asano,Y Kishida,A Baba, JOURNAL OF NEUROCHEMISTRY, LIPPINCOTT-RAVEN PUBL, Vol. 67, No. 5, p. 1840-1845, 1996/11
Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: An in situ hybridization study, H Hashimoto,H Nogi,K Mori,H Ohishi,R Shigemoto,K Yamamoto,T Matsuda,N Mizuno,S Nagata,A Baba, JOURNAL OF COMPARATIVE NEUROLOGY, WILEY-LISS, Vol. 371, No. 4, p. 567-577, 1996/08
cDNA cloning of a mouse pituitary adenylate cyclase-activating polypeptide receptor, H Hashimoto,K Yamamoto,N Hagihara,N Ogawa,A Nishino,H Aino,H Nogi,K Imanishi,T Matsuda,A Baba, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ELSEVIER SCIENCE BV, Vol. 1281, No. 2, p. 129-133, 1996/06
Involvement of Na+-Ca2+ exchanger in reperfusion-induced delayed cell death of cultured rat astrocytes, T Matsuda,K Takuma,E Nishiguchi,S Asano,H Hashimoto,J Azuma,A Baba, EUROPEAN JOURNAL OF NEUROSCIENCE, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 8, No. 5, p. 951-958, 1996/05
Expression pattern of messenger RNAs for prostanoid receptors in glial cell cultures, J Kitanaka,H Hashimoto,M Gotoh,K Kondo,K Sakata,Y Hirasawa,M Sawada,A Suzumura,T Marunouchi,T Matsuda,A Baba, BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 707, No. 2, p. 282-287, 1996/01
Effect of taurine on angiotensin II-induced expression of immediate early response genes in primary cultured neonatal rat heart cells, Takahashi K,Hashimoto H,Baba A,Schaffer S. W,Azuma J, Adv Exp Med Biol, Vol. 403, p. 297-304, 1996
STRUCTURE OF THE GENE ENCODING THE MOUSE PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE RECEPTOR, H AINO,H HASHIMOTO,N OGAWA,A NISHINO,K YAMAMOTO,H NOGI,S NAGATA,A BABA, GENE, ELSEVIER SCIENCE BV, Vol. 164, No. 2, p. 301-304, 1995/10
STIMULATION OF CYCLIC-AMP FORMATION BY PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE IS ATTENUATED BY GLUTAMATE IN RAT-BRAIN SLICES, K KONDO,H HASHIMOTO,K SAKATA,H SAGA,J KITANAKA,A BABA, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 67, No. 4, p. 399-401, 1995/04
EXPRESSION OF GLUTAMATE TRANSPORTERS IN CULTURED GLIAL-CELLS, K KONDO,H HASHIMOTO,J KITANAKA,M SAWADA,A SUZUMURA,T MARUNOUCHI,A BABA, NEUROSCIENCE LETTERS, ELSEVIER SCI PUBL IRELAND LTD, Vol. 188, No. 2, p. 140-142, 1995/03
CDNA CLONING OF A THROMBOXANE A(2) RECEPTOR FROM RAT ASTROCYTES, J KITANAKA,H HASHIMOTO,Y SUGIMOTO,M SAWADA,M NEGISHI,A SUZUMURA,T MARUNOUCHI,A ICHIKAWA,A BABA, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, ELSEVIER SCIENCE BV, Vol. 1265, No. 2-3, p. 220-223, 1995/03
CONSTITUTIVE ACTIVATION OF THE FAS LIGAND GENE IN MOUSE LYMPHOPROLIFERATIVE DISORDERS, D WATANABE,T SUDA,H HASHIMOTO,S NAGATA, EMBO JOURNAL, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 14, No. 1, p. 12-18, 1995/01
TUNICAMYCIN INHIBITS PROSTAGLANDIN-F2-ALPHA RECEPTOR-MEDIATED PHOSPHOINOSITIDE HYDROLYSIS IN CULTURED RAT ASTROCYTES, J KITANAKA,T HAMANO,M GOTOH,H HASHIMOTO,A BABA, NEUROCHEMICAL RESEARCH, PLENUM PUBL CORP, Vol. 19, No. 12, p. 1545-1550, 1994/12
CULTURED RAT ASTROCYTES POSSESS NA+-CA2+ EXCHANGER, K TAKUMA,T MATSUDA,H HASHIMOTO,S ASANO,A BABA, GLIA, WILEY-LISS, Vol. 12, No. 4, p. 336-342, 1994/12
CLONING AND EXPRESSION OF A CDNA FOR RAT PROSTAGLANDIN-F2-ALPHA RECEPTOR, J KITANAKA,H HASIMOTO,Y SUGIMOTO,M NEGISHI,H AINO,M GOTOH,A ICHIKAWA,A BABA, PROSTAGLANDINS, BUTTERWORTH-HEINEMANN, Vol. 48, No. 1, p. 31-41, 1994/07
IDENTIFICATION AND CHARACTERIZATION OF PARATHYROID-HORMONE PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR IN CULTURED ASTROCYTES, H HASHIMOTO,H AINO,N OGAWA,S NAGATA,A BABA, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 200, No. 2, p. 1042-1048, 1994/04
MOLECULAR-CLONING AND TISSUE DISTRIBUTION OF A RECEPTOR FOR PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, H HASHIMOTO,T ISHIHARA,R SHIGEMOTO,K MORI,S NAGATA, NEURON, CELL PRESS, Vol. 11, No. 2, p. 333-342, 1993/08
INHIBITORY GLUTAMATE RESPONSE ON CYCLIC-AMP FORMATION IN CULTURED ASTROCYTES, A BABA,H SAGA,H HASHIMOTO, NEUROSCIENCE LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 149, No. 2, p. 182-184, 1993/01
MECHANISM OF EXTRACELLULAR ATP-STIMULATED PHOSPHOINOSITIDE HYDROLYSIS IN RAT GLIOMA C(6) CELLS, J KITANAKA,H HASHIMOTO,M GOTOH,T MAYUMI,A BABA, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, WILLIAMS & WILKINS, Vol. 263, No. 3, p. 1248-1252, 1992/12
IDENTIFICATION OF THE PROSTACYCLIN RECEPTOR BY USE OF [15-3H1]19-(3-AZIDOPHENYL)-20-NORISOCARBACYCLIN, AN IRREVERSIBLE SPECIFIC PHOTOAFFINITY PROBE, S ITO,H HASHIMOTO,M NEGISHI,M SUZUKI,H KOYANO,R NOYORI,A ICHIKAWA, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 267, No. 28, p. 20326-20330, 1992/10
AN AZIDO-FUNCTIONALIZED ISOCARBACYCLIN ANALOG ACTING AS AN EFFICIENT PHOTOAFFINITY PROBE FOR A PROSTACYCLIN RECEPTOR, M SUZUKI,H KOYANO,R NOYORI,H HASHIMOTO,M NEGISHI,A ICHIKAWA,S ITO, TETRAHEDRON, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 48, No. 13, p. 2635-2658, 1992/03
TRANSLOCATION OF ALPHA-SUBUNITS OF STIMULATORY GUANINE NUCLEOTIDE-BINDING PROTEINS THROUGH STIMULATION OF THE PROSTACYCLIN RECEPTOR IN MOUSE MASTOCYTOMA-CELLS, M NEGISHI,H HASHIMOTO,A ICHIKAWA, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 267, No. 4, p. 2364-2369, 1992/02
PROSTAGLANDIN-E1 RECEPTOR FROM MOUSE MASTOCYTOMA P-815 CELLS COUPLES TO 60-KDA GTP-BINDING PROTEIN, H HASHIMOTO,R OGINO,H SAEKI,K YATSUNAMI,A ICHIKAWA, BIOCHIMICA ET BIOPHYSICA ACTA, ELSEVIER SCIENCE BV, Vol. 1095, No. 2, p. 140-144, 1991/10
TEI-9063, A STABLE AND HIGHLY SPECIFIC PROSTACYCLIN ANALOG FOR THE PROSTACYCLIN RECEPTOR IN MASTOCYTOMA P-815 CELLS, M NEGISHI,H HASHIMOTO,K YATSUNAMI,S KUROZUMI,A ICHIKAWA, PROSTAGLANDINS, BUTTERWORTH-HEINEMANN, Vol. 42, No. 3, p. 225-237, 1991/09
DIFFERENTIAL REGULATION OF THROMBIN-INDUCED OR ATP-INDUCED MOBILIZATION OF INTRACELLULAR CA2+ BY PROSTACYCLIN RECEPTOR IN MOUSE MASTOCYTOMA-CELLS, M NEGISHI,H HASHIMOTO,A ICHIKAWA, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 176, No. 1, p. 102-107, 1991/04
IDENTIFICATION OF A PROSTACYCLIN RECEPTOR COUPLED TO THE ADENYLATE-CYCLASE SYSTEM VIA A STIMULATORY GTP-BINDING PROTEIN IN MOUSE MASTOCYTOMA P-815 CELLS, H HASHIMOTO,M NEGISHI,A ICHIKAWA, PROSTAGLANDINS, BUTTERWORTH-HEINEMANN, Vol. 40, No. 5, p. 491-505, 1990/11
EFFECT OF TUNICAMYCIN ON FUNCTIONS OF PGE1 RECEPTORS FROM MOUSE MASTOCYTOMA P-815 CELLS, K YATSUNAMI,J FUJISAWA,H HASHIMOTO,K KIMURA,S TAKAHASHI,A ICHIKAWA, BIOCHIMICA ET BIOPHYSICA ACTA, ELSEVIER SCIENCE BV, Vol. 1051, No. 1, p. 94-99, 1990/01
2006 Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases neuronal cell death after focal ischemia associated with interlerukin-6 (IL-6)., Ohtaki H,Nakamachi T,Aizawa Y,Dohi K,Hodoyama K,Yofu S,Takaki A,Hashimoto H,Shintani N,Baba A,Kopf M,Iwakura Y,Arimura A,Shioda S, Proc Natl Acad Sci, No. 103, p. 7486-7493
2016 PACAP suppresses dry eye symptoms through stimulation of tear production., Nakamachi T,Aizawa Y,Ohtaki H,Yofu S,Seki T,Endo K,Wada Y,Kagami N,Dohi K,Arata S,Hashimoto H,Shintani N,Baba A,Mark L,Kiss P,Farkas J,Reglodi D,Shioda S, Nature Commun

Misc.

胎児期におけるPGD2シグナル活性化による社会性行動や神経細胞形態への影響, 菊池泰河,早田敦子,早田敦子,橘雅弥,橘雅弥,毛利育子,谷池雅子,橋本均,橋本均,橋本均,橋本均,橋本均, 日本薬理学雑誌, Vol. 157, No. Supplement, 2022
胎児期PGD2受容体アゴニスト暴露は社会性行動や神経細胞形態に影響を及ぼす, 早田敦子,早田敦子,菊池泰河,豊田博紀,毛利育子,橘雅弥,橘雅弥,加藤隆史,加藤隆史,谷池雅子,橋本均,橋本均,橋本均,橋本均,橋本均, 日本神経化学会大会抄録集(Web), Vol. 65th, 2022
ブチリルコリンエステラーゼの阻害は脳内アセチルコリンとグレリンシグナルの促進により認知機能障害を改善する, 塚田信司,東野功典,国本寿美子,田邊航,山口拓海,中川晋作,中川晋作,NIGEL Greig,橋本均,橋本均,橋本均,橋本均,橋本均,吾郷由希夫,吾郷由希夫, 日本薬理学雑誌, Vol. 155, No. Supplement, 2020
Behavioral and morphological abnormalities in a mouse model with copy number variation of the vasoactive intestinal peptide receptor VIPR2 gene, 陳露,竹内修斗,山田めゐ,宮岡辰典,山口拓海,中澤敬信,中澤敬信,中澤敬信,中川晋作,中川晋作,橋本均,橋本均,橋本均,橋本均,吾郷由希夫,吾郷由希夫,吾郷由希夫, 日本薬理学雑誌, Vol. 155, No. Supplement, 2020
マウス新生仔へのプロスタグランジンD2受容体DP1作動薬による神経細胞の形態や行動への影響, 早田敦子,奥田健太,毛利育子,橘雅弥,新谷勇介,菊池泰河,中澤敬信,谷池雅子,橋本均, 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, 日本臨床精神神経薬理学会・日本神経精神薬理学会, Vol. 28回・48回, p. 224-224, 2018/11
マウス新生仔へのプロスタグランジンD2受容体DP1作動薬による神経細胞の形態や行動への影響, 早田敦子,奥田健太,毛利育子,橘雅弥,新谷勇介,菊池泰河,中澤敬信,谷池雅子,橋本均, 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, 日本臨床精神神経薬理学会・日本神経精神薬理学会, Vol. 28回・48回, p. 224-224, 2018/11
iPS細胞を用いた精神・神経疾患研究の現状:創薬への期待 iPS細胞関連技術とヒト型疾患モデルマウスを用いた精神疾患の分子病態解析, 中澤敬信,橋本亮太,田熊一敞,橋本均, 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, 日本臨床精神神経薬理学会・日本神経精神薬理学会, Vol. 28回・48回, p. 125-125, 2018/11
High-resolution imaging of primate brains using FAST, Hashimoto H,Seiriki K,Kasai A,Nakazawa T,Inoue K,Takada M, International Workshop "Monitoring and manipulating brain function in non-human primates"（2018/7/31, 千葉市）, 2018/07
線維筋痛症モデルにおけるモルヒネ鎮痛欠如メカニズム, 根山広行,吾郷由希夫,橋本均,植田弘師, PAIN RESEARCH, 日本疼痛学会, Vol. 33, No. 2, p. 136-136, 2018/06
Whole-brain imaging analysis of animal models of neuropsychiatric disorders, Kaoru Seiriki,Atsushi Kasai,Hitoshi Hashimoto, Japanese Journal of Biological Psychiatry, Vol. 29, No. 1, p. 22-26, 2018/03
ヒトiPS細胞を利用した神経毒性評価の新たな展開と国際動向 iPS細胞関連技術を用いた統合失調症の分子病態解析および神経細胞分化の基盤技術開発, 中澤敬信,橋本亮太,田熊一敞,橋本均, 日本薬学会年会要旨集, (公社)日本薬学会, Vol. 138年会, No. 1, p. 132-132, 2018/03
精神疾患におけるVPAC2受容体の病態生理学的役割, 吾郷由希夫,早田敦子,橋本均, 日本薬理学雑誌, Vol. 151, No. 6, p. 249-253, 2018
FAST, High-speed serial-sectioning imaging for whole brain analysis with high scalability., Kasai A,Seiriki K,Hashimoto T,Niu M,Yamaguchi S,Naka Y,Igarashi H,Tamura M,Nakazawa T,Inoue K,Takada M,Fujita K,Hashimoto H, Neuroscience 2017(2017/11/13,Washington, DC, USA), 2017/11
全脳マッピングと神経活動操作による情動行動制御機構の解明, 笠井淳司,丹生光咲,勢力薫,五十嵐久人,桑木崇宏,田沼将人,中澤敬信,山口瞬,山中章弘,橋本均, 日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集, 日本生物学的精神医学会・日本神経精神薬理学会, Vol. 39回・47回, p. 173-173, 2017/09
iPS細胞を用いた精神疾患の分子病態研究の最前線と治療自閉スペクトラム症に高頻度に認めるPOGZ遺伝子座の患者特異的de novo変異の表現型解析, 中澤敬信,田熊一敞,橋本亮太,橋本均, 日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集, 日本生物学的精神医学会・日本神経精神薬理学会, Vol. 39回・47回, p. 130-130, 2017/09
治療抵抗性統合失調症の病態と治療治療抵抗性統合失調症ガイドラインから基礎研究まで, 橋本亮太,山森英長,安田由華,藤本美智子,菊地正隆,齋藤竹生,池田匡志,中澤敬信,橋本均,岩田仲生, 精神神経学雑誌, (公社)日本精神神経学会, No. 2017特別号, p. S596-S596, 2017/06
精神的ストレスにより活性化する神経核の情動行動における役割, 丹生光咲,笠井淳司,勢力薫,五十嵐久人,山口瞬,山中章弘,中澤敬信,橋本均, 日本薬学会年会要旨集, (公社)日本薬学会, Vol. 137年会, No. 3, p. 67-67, 2017/03
Regulation of neuropsychiatric and neurodevelopmental disorders by juvenile environmental factors, 田熊一敞,吾郷由希夫,原雄大,長谷部茂,中澤敬信,橋本均,松田敏夫, 日本生物学的精神医学会誌 = Japanese journal of biological psychiatry, 日本生物学的精神医学会 ; 2010-, Vol. 28, No. 1, p. 22-26, 2017/03
神経ペプチドPACAPおよびその受容体の種類と構造, 早田敦子,吾郷由希夫,橋本均, Clinical Neuroscience, Vol. 35, No. 8, p. 912-913, 2017
神経ペプチドPACAPおよびその受容体の発現分布と生理的作用, 早田敦子,吾郷由希夫,橋本均, Clinical Neuroscience, Vol. 35, No. 9, p. 1034-1036, 2017
神経ペプチドPACAPおよびその受容体をターゲットとした臨床応用, 早田敦子,吾郷由希夫,橋本均, Clinical Neuroscience, Vol. 35, No. 10, p. 1150-1151, 2017
Regulation of emotional behaviors by juvenile environmental factors, Takuma Kazuhiro,Ago Yukio,Hasebe Shigeru,Nakazawa Takanobu,Hashimoto Hitoshi,Matsuda Toshio, Folia Pharmacologica Japonica, The Japanese Pharmacological Society, Vol. 149, No. 2, p. 76-78, 2017
iPS細胞関連技術を用いた統合失調症のトランスレーショナルリサーチ (特集 iPS細胞を用いた精神疾患の研究), 中澤敬信,橋本亮太,田熊一敞,橋本均, 分子精神医学, 先端医学社, Vol. 16, No. 4, p. 248-254, 2016/10
iPS細胞技術を用いた統合失調症患者のクロザピン応答性の個人間の相違の分子機構解析, 中澤敬信,橋本亮太,橋本均, 日本神経精神薬理学会年会プログラム・抄録集, (一社)日本神経精神薬理学会, Vol. 46回, p. 143-143, 2016/07
認知機能制御におけるプロスタグランジンDP2受容体の役割(The role of prostanoid DP2 receptor in the regulation of cognitive function), 新谷紀人,尾中勇祐,叶拓也,中澤敬信,吾郷由希夫,松田敏夫,橋本亮太,大井一高,平井博之,永田欽也,中村正孝,笠井淳司,早田敦子,野,永安一樹,馬場明道,橋本均, 日本神経精神薬理学会年会プログラム・抄録集, (一社)日本神経精神薬理学会, Vol. 46回, p. 232-232, 2016/07
Overactivation of the VPAC2 receptor during the early postnatal period causes prefrontal synaptic abnormalities and cognitive dysfunction in mice, Yukio Ago,Atsuko Hayata,Takuya Kawanai,Ryosuke Yamauchi,James A. Waschek,Hitoshi Hashimoto, INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, OXFORD UNIV PRESS, Vol. 19, p. 180-181, 2016/06
高速・高精細全脳イメージング法FASTによるストレス負荷マウスの脳活動変化の検出, 笠井淳司,丹生光咲,勢力薫,山口瞬,中澤敬信,橋本均, 日本薬学会年会要旨集, (公社)日本薬学会, Vol. 136年会, No. 3, p. 59-59, 2016/03
Studies on the molecular mechanism of clozapine action with iPSC technology, Fujiwara Mikiya,Kikuchi Masataka,Nagayasu Kazuki,Nakazawa Takanobu,Yamamori Hidenaga,Kasai Atsushi,Hayata-Takano Atsuko,Shintani Norihito,Fujimoto Michiko,Yasuda Yuka,Ishikawa Mitsuru,Akamatsu Wado,Okano Hideyuki,Nakaya Akihiro,Hashimoto Hitoshi,Hashimoto Ryota, JOURNAL OF PHARMACOLOGICAL SCIENCES, Vol. 130, No. 3, 2016/03
自閉症モデルマウスにおける前頭前皮質ドパミン神経系の異常~ADHD治療薬による行動異常の改善, 吾郷由希夫,原雄大,前田優子,長谷部茂,橋本均,橋本均,松田敏夫,田熊一敞,田熊一敞, 日本神経精神薬理学会プログラム・抄録集, Vol. 46th, 2016
雌選択性試験：マウス間相互作用を基盤とした新規意欲／報酬探索行動評価系, 吾郷由希夫,長谷部茂,橋本均,田熊一敞,松田敏夫, 日本薬理学雑誌, Vol. 147, No. 4, p. 230-234, 2016
A new imaging system to detect whole brain structural and functional alterations at cellular and subcellular levels, Seiriki Kaoru,Kasai Atsushi,Niu Misaki,Yamaguchi Shun,Hashimoto Takeshi,Hashimoto Hitoshi, JOURNAL OF PHARMACOLOGICAL SCIENCES, Vol. 128, No. 3, 2015/07
PACAPシグナルによる精神神経機能調節におけるセロトニン2A受容体シグナルの関与, 早田敦子,狭間啓佑,森口啓太,吾郷由希夫,円丁直樹,中澤敬信,永安一樹,笠井淳司,尾中勇祐,新谷紀人,馬場明道,橋本均, 日本神経精神薬理学雑誌, Vol. 35, p. 55-56, 2015
Brain-enriched Sorting Nexin Family Proteins Regulate Spine Morphogenesis and Are Associated with Risk for Schizophrenia, Takanobu Nakazawa,Ryota Hashimoto,Asami Tanimura,Kazutaka Ohi,Hidenaga Yamamori,Yuka Yasuda,Satomi Umeda-Yano,Yuji Kiyama,Kohtarou Konno,Takafumi Inoue,Shusuke Numata,Tohru Ohnuma,Nakao Iwata,Norio Ozaki,Hitoshi Hashimoto,Masahiko Watanabe,Toshiya Manabe,Tadashi Yamamoto,Masatoshi Takeda,Masanobu Kano, NEUROPSYCHOPHARMACOLOGY, NATURE PUBLISHING GROUP, Vol. 39, p. S306-S307, 2014/12
iPS細胞を用いた精神疾患の分子病態研究の現状と展望 iPS細胞関連技術を用いた統合失調症研究, 中澤敬信,橋本亮太,永安一樹,安田由華,山森英長,梅田知美,藤本美智子,大井一高,石川充,赤松和土,岡野栄之,武田雅俊,橋本均, 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, 日本臨床精神神経薬理学会・日本神経精神薬理学会, Vol. 24回・44回, p. 121-121, 2014/11
自閉症の疾患特異的候補遺伝子の機能的スクリーニング系の確立, 松村憲佑,永安一樹,中澤敬信,安田由華,山森英長,梅田知美,大井一高,橋本亮太,武田雅俊,橋本均, 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, 日本臨床精神神経薬理学会・日本神経精神薬理学会, Vol. 24回・44回, p. 170-170, 2014/11
「脳の科学Up Date」最近の全脳三次元解析の現状と展望, 笠井淳司,橋本均, 脳21, Vol. 17, No. 4, p. 115-119, 2014/10
A CROSSTALK BETWEEN PACAPAND SEROTONIN 2A SIGNALING, Keita Moriguchi,Atsuko Hayata,Naoki Encho,Norihito Shintani,Akemichi Baba,Hitoshi Hashimoto, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 53, p. S148-S149, 2014/08
PACAP-PAC1 signaling pathway regulates internalization of serotonin 2A receptor in a protein kinase C and beta-arrestin2 dependent manner, A. Hayata,K. Moriguchi,N. Encho,N. Shintani,A. Baba,H. Hashimoto, INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, CAMBRIDGE UNIV PRESS, Vol. 17, p. 83-83, 2014/06
The balance between BMP and TGF-beta signaling at an early stage steers serotonergic differentiation from ES cells, Atsushi Yamasaki,Atsushi Kasai,Akihiro Toi,Maki Kurita,Atsuko Hayata-Takano,Kazuki Nagayasu,Norihito Shintani,Akemichi Baba,Hitoshi Hashimoto, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 181P-181P, 2014
Altered expression of PACAP in the mPFC in depression-like states induced by chronic social defeat stress, Keisuke Hazama,Atsushi Kasai,Sumiaki Ogawa,Atsuko Hayata,Norihito Shintani,Akemiti Baba,Hitoshi Hashimoto, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 187P-187P, 2014
APPLICATION OF THE THREE HIT THEORY IN PACAP HETERO-ZYGOUS MICE: MATERNAL SEPARATION AND CHRONIC STRESS INFLUENCE BNST CRF AND CPEW UCN1 IN AN INVERSE MANNER, B. Gaszner,J. Farkas,G. Bodnar,L. Kovacs,T. Gaszner,L. Gaspar,A. Balogh,B. Szalontai,H. Hashimoto,D. Reglodi,Kormos, V, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S192-S192, 2013/11
ROLES OF PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE (PACAP) IN NOCICEPTION AND INFLAMMATION IN AN IMMUNE MEDIATED ARTHRITIS MODEL, B. Botz,Horvath, I,K. Szigeti,D. Veres,D. Mathe,H. Hashimoto,D. Reglodi,T. Nemeth,M. Kovacs,A. Mocsai,Zs Helyes, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S189-S190, 2013/11
PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE PLAYS A KEY ROLE IN NITROGLYCEROL-INDUCED TRIGEMINOVASCULAR ACTIVATION IN MICE, A. Markovics,Kormos, V,B. Gaszner,A. Lashgarara,E. Szoke,K. Sandor,K. Szabadfi,B. Tuka,J. Tajti,J. Szolcsanyi,E. Pinter,H. Hashimoto,J. Kun,D. Reglodi,Zs Helyes, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S220-S220, 2013/11
PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) PLAYS SIGNIFICANT ROLES IN DENDRITIC SPINE FORMATION AND MORPHOLOGY, S. Higashi,K. Seiriki,A. Hayata,K. Ogata,N. Shintani,A. Kasai,D. Vaudry,A. Baba,H. Hashimoto, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S226-S226, 2013/11
ANALYSIS OF PACAP SIGNALING-MEDIATED RECEPTOR INTERNALIZATION USING THE HALOTAG SYSTEM, A. Hayata,N. Encho,K. Moriguchi,T. Fujino,N. Shintani,A. Kasai,A. Baba,H. Hashimoto, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S203-S203, 2013/11
THE ROLE OF ENDOGENOUS PACAP IN THE KIDNEY DURING ISCHAEMIA-REPERFUSION, E. Laszlo,P. Kiss,P. Szakaly,K. Kovacs,A. Varga,P. Degrell,G. Jancso,G. Horvath,H. Hasimoto,A. Lubics,A. Tamas,D. Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S215-S215, 2013/11
EFFECTS OF PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE ON SPERMATOGENESIS, A. Varga,T. Juhasz,P. Kiss,A. Tamas,R. Brubel,A. Vincze,H. Hashimoto,S. Cseh,B. Somoskoi,D. Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S197-S198, 2013/11
PRO-INFLAMMATORY AND PRO-NOCICEPTIVE ROLES OF PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE (PACAP) IN A SERUM TRANSFER ARTHRITIS MOUSE MODEL, B. Botz,Horvath, I,K. Szigeti,D. Veres,D. Mathe,H. Hashimoto,D. Reglodi,T. Nemeth,M. Kovacs,A. Mocsai,Zs Helyes, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S165-S165, 2013/11
DIFFERENCES BETWEEN WILD TYPE AND PACAP KO MICE IN RETINAL AGING, K. Szabadfi,P. Kiss,D. Reglodi,A. Szabo,B. Szalontai,K. Kovacs,A. Tamas,H. Hashimoto,Zs Helyes,S. Shioda,R. Gabriel, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 51, p. S225-S226, 2013/11
Effect of voluntary exercise on abnormal behaviors in PACAP-KO mice, Akira Nakagawa,Rui Fukuyama,Hiroshi Yamaguchi,Norihito Shintani,Hitoshi Hashimoto,Yukio Ago,Kazuhiro Takuma,Toshio Matuda, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 121, p. 81P-81P, 2013
Role of endogenous PACAP in myelination of the rodent brain: lessons from PACAP-deficient mice, A. Vincze,D. Reglodi,Helyes Zs,H. Hashimoto,N. Shintani,H. Abraham, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, p. S163-S164, 2012/11
Examination of PAC1-receptor and calcium-binding protein expression in the inner ear of wild type and PACAP deficient mice, A. Tamas,B. Fulop,P. Kiss,D. Reglodi,R. Gabriel,A. Nemeth,H. Hashimoto,A. Baba,K. Szabadfi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, p. S148-S148, 2012/11
Examination of proteomic profiles and anorganic composition of samples from PACAP deficient mice, L. Mark,G. Maasz,T. Lorand,A. Tamas,P. Kiss,M. Wlaschits,M. Triphan,M. Opsahl,B. Narve,D. Jedlicska,K. Csanaky,E. Banki,R. Brubel,H. Hashimoto,N. Shintani,A. Baba,D. Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, p. S161-S162, 2012/11
Examination of PAC1-receptor and calcium-binding protein expression in the inner ear of wild type and PACAP deficient mice, A. Tamas,B. Fulop,P. Kiss,D. Reglodi,R. Gabriel,A. Nemeth,H. Hashimoto,A. Baba,K. Szabadfi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, p. S150-S151, 2012/11
PACAP stimulates the lacrimation via aquaporine 5 translocatoin in mouse, T. Nakamachi,Y. Aizawa,H. Ohtaki,T. Seki,Y. Wada,N. Kagami,S. Arata,H. Hashimoto,N. Shintani,A. Baba,J. Farkas,D. Reglodi,S. Shioda, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, p. S141-S141, 2012/11
Psychiatric implications of PACAP-dependent signaling, Hitoshi Hashimoto,Kaoru Seiriki,Katsuya Ogata,Keisuke Hazama,Norihito Shintani,Atsuko Hayata-Takano,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 48, p. S162-S162, 2012/11
Selective involvement of prostanoid receptor CRTH2 in depression-like behaviors, N. Shintani,Y. Onaka,R. Takenaga,T. Kanoh,R. Haba,A. Hayata,H. Hirai,K. Nagata,M. Nakamura,A. Baba,H. Hashimoto, JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Vol. 123, p. 73-73, 2012/10
PACAP stimulates tear secretion via AQP5 translocation in mouse, T. Nakamachi,Y. Aizawa,H. Ohtaki,S. Yofu,Y. Wada,T. Seki,N. S. Arata,Shintani,H. Hashimoto,A. Baba,Seiji Shioda, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 177, p. S28-S28, 2012/08
Pituitary adenylate cyclase-activating polypeptide (PACAP) plays significant roles in mental function and neuronal development, A. Hayata,K. Seiriki,M. Tajiri,K. Ogata,N. Shintani,A. Baba,H. Hashimoto, INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, OXFORD UNIV PRESS, Vol. 15, p. 202-203, 2012/06
HPGB, an inhibitor for mitochondrial fusion, promotes mitophagy, Shintaro Higashi,Norihito Shintani,Kazuhiko Katagi,Kazuya Ikeda,Mai Koumoto,Natsumi Hiraki,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 74P-74P, 2012
脳とくすりセロトニンシグナルと発達障害, 早田敦子,橋本均,大阪大学大学院大阪大学・金沢大学・浜松医科大学連合小児発達学研究科附属子どものこころの分子統御機構研究センター, 脳21, (株)金芳堂, Vol. 14, No. 2, p. 175-179, 2011/04
創薬シリーズトランスレーショナルリサーチ精神疾患のトランスレーショナルリサーチ統合失調症, 橋本亮太,安田由華,大井一高,福本素由己,山森英長,新谷紀人,橋本均,馬場明道,武田雅俊,浜松医科大学連合小児発達学研究科附属子どものこころの分子統御機能研究センター, 日本薬理学雑誌, (公社)日本薬理学会, Vol. 137, No. 2, p. 79-82, 2011/02
PACAP is implicated in regulation of neurite and dendritic spine formation, Katsuya Ogata,Atsuko Hayata,Kaoru Seiriki,Keisuke Hazama,Hisae Momosaki,Norihito Shintani,Akemichi Baba,Hitoshi Hashimoto, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 93P-93P, 2011
INVESTIGATING SENSORY AND MOTOR FUNCTIONS OF PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE DEFICIENT MICE UNDER NORMAL AND NEUROPATHIC CONDITIONS, B. Botz,A. Imreh,K. Elekes,E. Szoke,K. Sandor,D. Reglodi,E. Pinter,J. Szolcsanyi,H. Hashimoto,Zs Helyes, NEUROPEPTIDES, CHURCHILL LIVINGSTONE, Vol. 44, No. 6, p. 539-539, 2010/12
ROLE OF PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE (PACAP) IN NITROGLYCEROL-INDUCED TRIGEMINOVASCULAR ACTIVATION IN MICE, A. Markovics,A. Lashgarara,E. Szoke,K. Sandor,B. Tuka,V. Kormos,J. Tajti,J. Szolcsanyi,B. Gaszner,D. Reglodi,H. Hashimoto,Zs Helyes, NEUROPEPTIDES, CHURCHILL LIVINGSTONE, Vol. 44, No. 6, p. 543-543, 2010/12
The role of endogenous PACAP in protection against hypoxia and oxidative stress: in vitro studies in PACAP knockout mice, Gabriella Horvath,Peter Szakaly,Boglarka Racz,Peter Kiss,Zsuzsanna Helyes,Andrea Tamas,Andrea Lubics,Hitoshi Hashimoto,Akemichi Baba,Norihito Shintani,Dora Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 310-310, 2010/11
The roles of pancreatic PACAP in cerulein-induced pancreatitis, Yusuke Sakurai,Ken-ichi Hamagami,Akihiro Arimori,Hiroaki Inoue,Norihito Shintani,Naoko Higuchi,Kazuya Ikeda,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 311-311, 2010/11
Altered emotional and cognitive function in PACAP-deficient mice: a novel animal model for psychiatric disorder, Norihito Shintani,Hitoshi Hashimoto,Atsuko Hayata,Katsuya Ogata,Ryota Haba,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 278-279, 2010/11
PACAP plays a crucial role in the stress-induced activation of HPA-axis, Atsuko Hayata,Norihito Shintani,Yoko Saida,Michiya Kakuda,Naohiro Tsukiyama,Katsuya Ogata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 301-302, 2010/11
Intra-islet PACAP protects pancreatic beta-cells against glucotoxicity and lipotoxicity, Masanori Nakata,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Toshihiko Yada, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 307-307, 2010/11
PACAP protects mice with dextran sodium sulfate-induced acute colitis, Yasu-Taka Azuma,Mitsuru Kuwamura,Norihito Shintani,Hidemitsu Nakajima,Hitoshi Hashimoto,Akemichi Baba,Tadayoshi Takeuchi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 314-315, 2010/11
Effects of environmental factors during development on abnormal phenotypes in PACAP knock-out mice, Toshihiro Ishihama,Shunsuke Kataoka,Chika Manabe,Yukio Ago,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 302-303, 2010/11
Impaired nocifensive behaviors and mechanical hyperalgesia, but enhanced thermal hyperalgesia in PACAP knockout mice, Katalin Sandor,Viktoria Kormos,Balint Botz,Andras Imreh,Kata Boelcskei,Janos Szolcsanyi,Dora Reglodi,Balazs Gaszner,Hitoshi Hashimoto,Akemichi Baba,Zsuzsanna Helyes, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 309-309, 2010/11
Identification of a novel signaling cascade specifically involved in the light-induced phase advance of circadian rhythm by using PACAP knockout mice, Michiyoshi Hatanaka,Norihito Shintani,Chihiro Kawaguchi,Reiko Nakamura,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 297-298, 2010/11
The in vivo role of endogenous PACAP kidney ischemia/reperfusion: studies with knockout mice and radioimmunoassay, Peter Szakaly,Peter Kiss,Dora Reglodi,Eszter Laszlo,Tamas Magyarlaki,Jozsef Nemeth,Marius Opsahl,Narve Braaten,Zsuzsanna Helyes,Andrea Tamas,Andrea Lubics,Hitoshi Hashimoto,Akemichi Baba,Norihito Shintani,Gabriella Horvath,Balazs Sumegi,Boglarka Racz, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 316-317, 2010/11
Increased stathmin1 expression in the dentate gyrus causes abnormal axonal arborizations potential relevance to schizophrenia, Kohei Yamada,Shinsuke Matsuzaki,Tsuyoshi Hattori,Ryusuke Kuwahara,Manabu Taniguchi,Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Natsuko Kumamoto,Kazuo Yamada,Takeo Yoshikawa,Taiichi Katayama,Masaya Tohyama, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 300-300, 2010/11
15-Deoxy-Delta-prostaglandin J(2) enhances NGF-induced neurite outgrowth in PC12 cells via a CRTH2 receptor-p38 MAP kinase pathway, Norihiro Shibata,Michiyoshi Hatanaka,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 302-302, 2010/11
Extent of retinal damage in carotid artery occlusion-induced hypoperfusion model in PACAP-deficient mice, Tamas Atlasz,Krisztina Szabadfi,Peter Kiss,Andrea Tamas,Hitoshi Hashimoto,Akemichi Baba,Norihito Shintani,Robert Gabriel,Zsuzsanna Helyes,Dora Reglodi, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 42, No. 3, p. 304-305, 2010/11
新規ドライアイ疾患モデルとしてのPACAPノックアウトマウスの評価(Evaluation of PACAP knockout mouse as novel dry eye disease model), Nakamachi Tomoya,Aizawa Youichi,Ohtaki Hirokazu,Sek Tamotsu,Endo Kimi,Arata Satoru,Shintani Norihito,Hashimoto Hitoshi,Baba Akemichi,Shioda Seiji, Experimental Animals, (公社)日本実験動物学会, Vol. 59, No. 3, p. S44-S44, 2010/05
Increased sensitivity of PACAP knockout mice to retinal ischemia, D. Reglodi,K. Szabadfi,P. Kiss,A. Tamas,H. Hashimoto,A. Baba,N. Shintani,R. Gabriel,Z. Helyes,T. Atlasz, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 24, 2010/04
Impaired nocifensive behaviours and mechanical hyperalgesia, but enhanced thermal hyperalgesia in pituitary adenylate-cyclase activating polypeptide deficient mice, K. Sandor,Kormos, V,B. Botz,A. Imreh,K. Bolcskei,D. Reglodi,J. Szolcsanyi,N. Shintani,H. Hashimoto,A. Baba,Zs Helyes, ACTA PHYSIOLOGICA HUNGARICA, AKADEMIAI KIADO RT, Vol. 97, No. 1, p. 132-132, 2010/03
PACAP遺伝子欠損マウスにおける涙液分泌機能異常, 中町智哉,会沢洋一,大滝博和,養父佐知子,関保,遠藤貴美,荒田悟,新谷紀人,橋本均,馬場明道,塩田清二, 解剖学雑誌, (一社)日本解剖学会, Vol. 85, No. Suppl., p. 108-108, 2010/03
HPGB is a novel factor that inhibits mitochondrial fusion and membrane potential, Hikaru Kamemato,Kazuya Ikeda,Norihito Shintani,Shintaro Higashi,Mai Koumoto,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 124P-124P, 2010
5-HT2 agonist DOI-induced psychomotor behavior in PACAP heterozygous knockout (PACAP+/-) mice, Keisuke Hazama,Kazuki Uetsuki,Minako Taziri,Katsuya Ogata,Atsuko Hayata,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 226P-226P, 2010
Involvement of novel prostanoid receptor CRTH2 in LPS-induced sickness behaviors, Ryota Haba,Norihito Shintani,Hyper Wang,Yusuke Onaka,Atsuko Hayata,Hitoshi Hashimoto,Hiroyuki Hirai,Kinya Nagata,Masataka Nakamura,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 63P-63P, 2010
Increased stathmin1 expression in the dentate gyrus of mice causes abnormal axonal arborizations, Kohei Yamada,Shinsuke Matsuzaki,Tsuyoshi Hattori,Ryusuke Kuwahara,Manabu Taniguchi,Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Natsuko Kumamoto,Kazuo Yamada,Takeo Yoshikawa,Taiichi Katayama,Masaya Tohyama, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E284-E284, 2010
Roles of neuropeptide PACAP in enriched environment-induced neurogenesis and neurotrophic/growth factor expression in the hippocampus, Yukio Ago,Masanori Yoneyama,Kiyokazu Ogita,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Kazuhiro Takuma,Toshio Matsuda, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E367-E367, 2010
Generation of highly purified serotonergic neurons from mouse ES cells, Takeshi Shimada,Hitoshi Hashimoto,Kikuko Shinohara,Atsushi Yamasaki,Yoshihiro Takai,Norihito Shintani,Atsuko Hayata,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 92P-92P, 2010
Involvement of a prostanoid receptor CRTH2 in the LPS-induced decrease in object exploration behavior, Ryota Haba,Norihito Shintani,Hyper Wang,Yusuke Onaka,Atsuko Hayata,Hitoshi Hashimoto,Hiroyuki Hirai,Kinya Nagata,Masataka Nakamura,Akemichi Baba, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E80-E81, 2010
Interaction between genetic and non-genetic factors modulates psychomotor behaviors in PACAP-heterozygous knockout mice, Keisuke Hazama,Atsuko Hayata,Kazuki Uetsuki,Katsuya Ogata,Minako Taziri,Hisae Momosaki,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E82-E82, 2010
Mice lacking L-PGDS showed specific impairment in the light-induced phase advance of locomotor rhythm, Michiyoshi Hatanaka,Norihito Shintani,Ai Kuromi,Norihiro Shibata,Hitoshi Hashimoto,Kosuke Aritake,Yoshihiro Urade,Osamu Hayaishi,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 123P-123P, 2010
Effects of PACAP on autonomic nerves innervating peripheral tissue, Mamoru Tanida,Norihito Shintani,Michiyoshi Hatanaka,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 60, p. S150-S150, 2010
Cerulein-induced pancreatitis in PACAP knockout mice, Yusuke Sakurai,Akihiro Arimori,Hiroaki Inoue,Norihito Shintani,Atsuko Hayata,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 166P-166P, 2010
Decreased nocifensive behaviours and mechanical hyperalgesia in PACAP deficient mice, K. Sandor,V. Kormos,B. Botz,A. Imreh,K. Bolcskei,D. Reglodi,B. Gaszner,J. Szolcsanyi,N. Shintani,H. Hashimoto,A. Baba,Zs. Helyes, NEUROPEPTIDES, CHURCHILL LIVINGSTONE, Vol. 43, No. 5, p. 439-439, 2009/10
ENVIRONMENTAL FACTORS DURING DEVELOPMENT REGULATE THE BEHAVIORAL PHENOTYPES OF PACAP KNOCKOUT MICE, T. Ishihama,S. Kataoka,C. Manabe,Y. Ago,N. Shintani,H. Hashimoto,A. Baba,K. Takuma,T. Matsuda, JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 110, p. 264-264, 2009/09
FUNCTIONAL ANALYSIS OF ONE OF THE SUSCEPTIBILITY GENES FOR SCHIZOPHRENIA, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, YAMADA K.,MATSUZAKI S.,HATTORI T.,SHINTANI N.,HASHIMOTO H.,BABA A.,TOHYAMA M., Vol. 35, p. 50-50, 2009/06/12
マウスのドキソルビシン心筋障害モデルにおけるPituitary Adenylate Cyclase Activating Polyeptide(PACAP)の心筋保護効果, 森敬善,中町智哉,大滝博和,養父佐知子,佐藤敦,鈴木洋,嶽山陽一,新谷紀人,橋本均,馬場明道,塩田清二, 解剖学雑誌, (一社)日本解剖学会, Vol. 84, No. Suppl., p. 207-207, 2009/03
PACAP欠損マウスにおけるDSS誘発性腸炎の増悪, 東泰孝,新谷紀人,桑村充,中嶋秀満,橋本均,橋本均,馬場明道,竹内正吉, 消化器と免疫, No. 45, 2009
DSS誘発性大腸炎におけるPACAPの機能的役割, 東泰孝,桑村充,新谷紀人,中嶋秀満,橋本均,橋本均,馬場明道,竹内正吉, 日本薬理学会近畿部会プログラム・要旨集, Vol. 115th, 2009
DSS誘発性大腸炎におけるPACAPの機能的役割, 東泰孝,桑村充,新谷紀人,中嶋秀満,橋本均,橋本均,馬場明道,竹内正吉, 日本薬理学雑誌, Vol. 134, No. 4, 2009
IDENTIFICATION OF HPGB, A NOVEL GENE INVOLVE WITH MITOCHONDRIAL MORPHOLOGY AND/OR FUNCTION, Kazuya Ikeda,Kazuyuki Kitamura,Hikaru Kamemoto,Shintaro Higashi,Yusuke Sakurai,Ken-ichi Hamagami,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 348-348, 2009
Phenotypic changes associated with noggin-induced neuronal differentiation of embryonic stem (ES) cells, Kikuko Shinohara,Takeshi Shimada,Yoshihiro Takai,Atsushi Yamasaki,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 109, p. 64P-64P, 2009
Behavioral analysis of transgenic mouse overexpressing dysbindin-1, a susceptibility gene for schizophrenia, Hironori Takamura,Ryota Hashimoto,Norihito Shintani,Ryota Haba,Yuka Yasuda,Kazutaka Ohi,Motoyuki Fukumoto,Hidenaga Yamamori,Hitoshi Hashimoto,Akemichi Baba,Masatoshi Takeda, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S122-S122, 2009
PACAP induces early growth response gene in cortical neuron, Katsuya Ogata,Kazuki Uetsuki,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 109, p. 86P-86P, 2009
Functional roles of PACAP-Reg III beta signaling in pancreatic islet under diabetic condition, Norihito Shintani,Ken-ichi Hamagami,Keisuke Kusumoto,Yusuke Sakurai,Kazuya Ikeda,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 109, p. 92P-92P, 2009
Apelin is required for the development of oxygen-induced retinopathy, Atsushi Kasai,Toshihiko Kinjo,Yasuhiro Yoshioka,Akiko Yamamuro,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba,Sadaaki Maeda, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 109, p. 201P-201P, 2009
L-PGDS-PGD2-CRTH2 SIGNALING IS A NOVEL SIGNALING CASCADE SPECIFICALLY INVOLVED IN LIGHT-INDUCED PHASE ADVANCE OF CIRCADIAN RHYTHM, Norihito Shintani,Chihiro Kawaguchi,Reiko Nakamura,Yasushi Isojima,Rie Tsuchida,Michiyoshi Hatanaka,Hitoshi Hashimoto,Yukihiko Sugimoto,Hiroyuki Hirai,Kinya Nagata,Masataka Nakamura,Toshiyuki Matsuoka,Shu Narumiya,Katsuya Nagai,Akemichi Baba, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 286-286, 2009
PACAP receptor, HASHIMOTO Hitoshi,SHINTANI Norihito,BABA Akemichi, Folia pharmacologica Japonica, Vol. 132, No. 3, p. 189-191, 2008/09/01
Possible involvement of neuropeptide PACAP in the molecular basis of schizophrenia, SHINTANI Norihito,HASHIMOTO Hitoshi,KAKUDA Michiya,BABA Akemichi, Vol. 19, No. 1, p. 7-13, 2008/03/25
tPAを超える新しい脳梗塞治療薬開発のための病態解明と治療薬候補分子 PACAPによる虚血性神経細胞死抑制と分子制御機構, 塩田清二,大滝博和,中町智哉,馬場明道,橋本均, 日本薬学会年会要旨集, (公社)日本薬学会, Vol. 128年会, No. 1, p. 157-157, 2008/03
Differential deficits in non-visual photoreceptive response in PACAP knockout mice, Michiyoshi Hatanaka,Chihiro Kawaguchi,Norihito Shintani,Mamoru Tanida,Yasushi Isojima,Ryouta Haba,Hitoshi Hashimoto,Katsuya Nagai,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 106, p. 139P-139P, 2008
Involvement of acetylcholine receptors in galantamine-induced improvement of prepulse inhibition deficits in mice, Hisako Kobayashi,Ken Koda,Koji Yano,Yukio Ago,Hitoshi Hashimoto,Akemichi Baba,Toshio Matsuda, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 106, p. 231P-231P, 2008
ニューロペプチドPACAPと精神神経機能 : 変異マウスからの予想外の知見, 橋本均,新谷紀人,馬場明道, 生化学, 日本生化学会, Vol. 79, No. 4, p. 375-379, 2007/04/25
PACAPはIL-6を介して虚血性神経細胞死を抑制する, 中町智哉,大滝博和,土肥謙二,養父佐知子,新谷紀人,橋本均,馬場明道,塩田清二, 解剖学雑誌, (一社)日本解剖学会, Vol. 82, No. Suppl., p. 196-196, 2007/03
マウス胃体部における抑制性伝達物質間の相互作用とK+チャネルの関連性, 東泰孝,萩清美,中嶋秀満,新谷紀人,橋本均,馬場明道,竹内正吉, 日本獣医学会学術集会講演要旨集, Vol. 143rd, 2007
マウス胃体部における抑制性伝達の解明-抑制性伝達物質間の相互作用とK+チャネルによる調節-, 萩清美,中嶋秀満,東泰孝,新谷紀人,橋本均,馬場明道,竹内正吉, 日本薬理学雑誌, Vol. 129, No. 2, 2007
Function analysis of pituitary adenylate cyclase-activating polypeptide associated with schizophrenia in hippocampal dentate gyrus, Kohei Yamada,Shinsuke Matsuzaki,Tsuyoshi Hattori,Hitoshi Hashimoto,Norihito Shintani,Akemichi Baba,Masaya Tohyama, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S221-S221, 2007
PACAP-regulated beta-cell proliferation: Implication of RegIIIbeta, Ken-Ichi Hamagami,Hitoshi Hashimoto,Shuhei Tomimoto,Yukihiko Sugimoto,Norihito Shintani,Akemichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 33, No. 3, p. 334-334, 2007
PACAP deficient mice exhibit light parameter dependent abnormalities of nonvisual photoreception, Yasushi Isojima,Chihiro Kawaguchi,Norihito Shintani,Michiyoshi Hatanaka,Xiaohong Guo,Katsuya Nagai,Hitoshi Hashimoto,Akemichi Baba, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S168-S168, 2007
Co-administration of amphetamine and serotonin (5-HT)(1A) agonist decreases the locomotor activity of mice in a novel environment, Mariko Kuroda,Rie Tsuchida,Masahiro Kubo,Michiya Kakuda,Norihito Shintani,Yukio Ago,Toshio Matsuda,Hitoshi Hashimoto,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, p. 239P-239P, 2007
Lack of apelin results in retardation of retinal vascular development, Atsushi Kasai,Norihito Shintani,Hideaki Kato,Satoshi Matsuda,Fumi Gomi,Hitoshi Hashimoto,Michiya Kakuda,Yasuo Tano,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, p. 63P-63P, 2007
PACAP and schizophrenia: from experimental to clinical, Hitoshi Hashimoto,Ryota Hashimoto,Norihito Shintani,Toshio Matsuda,Yukio Ago,Michiya Kakuda,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, p. 24P-24P, 2007
Evidence that the PACAP gene contributes to the risk of schizophrenia, Hitoshi Hashimoto,Ryota Hashimoto,Norihito Shintani,Toshio Matsuda,Yukio Ago,Michiya Kakuda,Akernichi Baba, JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Vol. 33, No. 3, p. 322-322, 2007
統合失調症とセロトニン1A受容体, 吾郷由希夫,角田亨也,橋本均,馬場明道,松田敏夫, 脳２１, Vol. 10, p. 256-260, 2007
Altered non-visual photoreceptive response in PACAP-knockout mice, Norihito Shintani,Chihiro Kawaguchi,Yasushi Isojima,Michiyoshi Hatanaka,Hitoshi Hashimoto,Katsuya Nagai,Akemichi Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 135, No. 3, p. 157-157, 2006/08
RegIIIbeta is a candidate gene for regulating glucose-dependent beta-cell proliferation, Ken-ich Hamagami,Naoko Higuchi,Shuhei Tomimoto,Yukihiko Sugimoto,Norihito Shintani,Hitoshi Hashimoto,Akemichi Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 135, No. 3, p. 127-128, 2006/08
Role of the neuropeptide PACAP in the regulation of higher brain functions, H. Hashimoto,N. Shintani,A. Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 135, No. 3, p. 193-194, 2006/08
Role of the neuropeptide PACAP in the regulation of psychomotor function, H. Hashimoto,N. Shintani,A. Baba, JOURNAL OF NEUROCHEMISTRY, BLACKWELL PUBLISHING, Vol. 98, p. 15-15, 2006/07
Impaired memory retention in mice lacking pituitary adertylade cyclase-activating polypeptide (PACAP) in an object recognition test, Xiaohong Guo,Shintani Norihito,Ago Yukio,Nakajima Miki,Hashimoto Hitoshi,Baba Akemichi, ACTA PHARMACOLOGICA SINICA, BLACKWELL PUBLISHING, Vol. 27, p. 87-87, 2006/07
PACAP knockout mouse : a novel genetic model of psychiatric disorders, HASHIMOTO Hitoshi,SHINTANI Norihito,BABA Akemichi, Vol. 17, No. 1, p. 47-52, 2006/03/25
PACAP knockout mice: A new model for psychomotor dysfunction, H Hashimoto,N Shintani,Y Ago,T Matsuda,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 20P-20P, 2006
PACAP's role in the development of acute pancreatitis, N Higuchi,K Hamagami,K Ikeda,N Shintani,H Hashimoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 162P-162P, 2006
Antagonist of NMDA receptor attenuated jumping behaviors of PACAP-deficient mice, N Kawagishi,T Shimada,A Yamamoto,K Tanaka,M Kuroda,N Shintani,H Hashimoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 205P-205P, 2006
Neuronal differentiation of ES cells grown on Matrigel, reconstituted basement membranes, T Shimada,H Hashimoto,M Hirose,N Shintani,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 256P-256P, 2006
Amphetamine-induced attenuation of hyperactivity and prepulse inhibition deficits in mice lacking PACAP, Norihito Shintani,Hitoshi Hashimoto,Kazuhiro Tanaka,Yukio Ago,Michiya Kakuda,Toshio Matsuda,Akemichi Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 101, p. 113-113, 2006
High frequency of ophthalmic malformation and altered thermal pain response in mice lacking apelin, M Kakuda,A Kasai,N Shintani,H Hashimoto,H Katoh,T Matsuda,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 238P-238P, 2006
Expression of mRNA for APJ, an orphan GPCR, in adipose tissue of obesity-associated diabetic mice, C Ishida,A Kasak,N Shintani,H Hashimoto,T Matuda,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 216P-216P, 2006
Neuroprotective mechanism of PACAP after focal ischemia in mouse, H Ohtaki,T Nakamachi,K Dohi,K Hodoyama,H Hashimoto,N Shintani,A Baba,A Arimura,S Shioda, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 130, No. 3, p. 149-149, 2005/09
Lack of trimethyltin (TMT)-induced elevation of plasma corticosterone in PACAP-deficient mice, Y Morita,D Yanagida,N Shintani,K Ogita,N Nishiyama,H Hashimoto,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 130, No. 3, p. 171-171, 2005/09
PACAP-induced differentiation and inhibition of self-renewal in neural precursor cells, M Hirose,H Hashimoto,M Nakanishi,N Shintani,J Iga,N Arakawa,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 130, No. 3, p. 164-165, 2005/09
Involvement of serotonergic systems in psychomotor abnormalities in mice lacking PACAP, H Hashimoto,N Shintani,Ago, I,T Matsuda,A Baba, REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, Vol. 130, No. 3, p. 164-164, 2005/09
PACAP遺伝子欠損マウスを用いた局所脳虚血後の神経細胞死に対するPACAP効果, 程山恵,大滝博和,中町智哉,遠藤さくら,養父佐知子,土肥謙二,新谷紀人,馬場明道,橋本均,塩田清二, 解剖学雑誌, (一社)日本解剖学会, Vol. 80, No. Suppl., p. 227-227, 2005/03
Apelin-induced chemotaxic migration of retinal endothelial cells, M Oda,N Shintani,A Kasai,M Kakuda,H Hashimoto,T Matsuda,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 298P-298P, 2005
A link between up-regulation of pituitary adenylate cyclase-activating polypeptide and induction of neuropathic pain following nerve injury, S Matsumura,N Shintani,T Mabuchi,K Takagi,E Ashitaka,H Hashimoto,T Minami,A Baba,S Ito, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 39P-39P, 2005
5-HT1A receptor is involved in amphetamine-induced paradoxical calming effect in PACAP-deficient mice, K Tanaka,N Kawagishi,H Hashimoto,N Shintani,T Shimada,A Yamamoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 128P-128P, 2005
Attenuation of neuronal damage by trimethyltin (TMT) in mice lacking PACAP (PACAP-KO), Y Morita,D Yanagida,N Shintani,K Ogita,N Nishiyama,H Hashimoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 208P-208P, 2005
PACAP-Reg signaling inhibits diabetes-induced islet hyperplasia, K Hamagami,N Higuchi,S Tomimoto,Y Sugimoto,N Shintani,H Hashimoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 77P-77P, 2005
Serotonin 2 receptor is involved in increased immobility in the forced swim test in PACAP-deficient mice, A Yamamoto,K Tanaka,H Hashimoto,N Shintani,M Nakajima,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 151P-151P, 2005
Apelin is a novel angiogenic factor, A Kasai,N Shintani,M Oda,M Kakuda,H Hashimoto,T Matsuda,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 133P-133P, 2005
PACAP knockout phenotypes: Functional changes in the CNS and platelets, H Hashimoto,N Shintani,K Freson,C Van Geet,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 39P-39P, 2005
Molecular and pharmacological analysis of neuropeptide PACAP functions, Vol. 43, No. 4, p. 687-701, 2004/12/20
Effects of transgenic overexpression of pancreatic PACAP on obesity-associated diabetes, Y Kawabata,S Tomimoto,H Hashimoto,K Hamagami,N Shintani,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 207P-207P, 2004
Light-induced protein phosphorylation and c-Fos expression in the suprachiasmatic nucleus in mice lacking PACAP, C Kawaguchi,Y Isojima,N Shintani,H Hashimoto,K Nagai,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 300P-300P, 2004
The effects of glia-conditioned media on proliferation and differentiation of neural stem cells, J Iga,M Hirose,M Nakanishi,N Shintani,H Hashimoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 227P-227P, 2004
Relevance of PACAP-deficient mice as an animal model of psychiatric disorders, N Shintani,H Hashimoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 16P-16P, 2004
In vivo functional analysis of the neuropeptide PACAP using gene-targeted mice, HASHIMOTO Hitoshi,SHINTANI Norihito, Folia Pharmacologica Japonica, The Japanese Pharmacological Society, Vol. 122, No. 5, p. 427-436, 2003/11/01
Effect of haloperidol on abnormal phenotypes in PACAP knockout mice., K Tanaka,C Kawaguchi,N Shintani,A Yamamoto,H Hashimoto,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 121P-121P, 2003
Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP)., A Baba,N Shintani,H Hashimoto, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 54P-54P, 2003
Transgenic mice overexpressing PACAP in pancreatic beta cells: acute and chronic effects on insulin/glucose homeostasis., H Hashimoto,S Tomimoto,N Shintani,A Baba, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 54P-54P, 2003
神経系における下垂体アデニル酸シクラーゼ活性化ポリペプチド(PACAP)の生理的意義, 橋本均, 藥學雜誌, 社団法人日本薬学会, Vol. 122, No. 12, p. 1109-1121, 2002/12/01
Gene expression of PACAP and its receptors in the ES cell-derived neuronal stem cells, M Hirose,H Hashimoto,N Shintani,N Arakawa,A Baba, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 143P-143P, 2002
Phenotypic modification by genetic background in PACAP knockout mice, N Shintani,H Hashimoto,K Tanaka,C Kawaguchi,M Imai,W Mori,S Tomimoto,T Matsuda,A Baba, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 143P-143P, 2002
Brain serotonergic abnormalities in PACAP knockout mice, K Tanaka,C Kawaguchi,N Shintani,W Mori,M Sakaue,H Hashimoto,T Matsuda,A Baba, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 195P-195P, 2002
Involvement of Ca2+ influx in ERK and p38 MAP kinase activation by PACAP in PC12 cells, Y Sakai,H Hashimoto,N Shintani,A Ichibori,A Baba, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 142P-142P, 2002
Physiological function and mechanism of action of neuropeptide PACAP, HASHIMOTO Hitoshi, Vol. 72, No. 3, p. 191-193, 2000/03/25
DISTRIBUTION OF THE MESSENGER-RNA FOR A PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE RECEPTOR IN RAT-BRAIN AND PITUITARY, H HASHIMOTO,H NOGI,R SHIGEMOTO,K MORI,S NAGATA,A BABA, JOURNAL OF NEUROCHEMISTRY, LIPPINCOTT-RAVEN PUBL, Vol. 65, p. S99-S99, 1995
INHIBITORY GLUTAMATE RESPONSE ON ADENYLATE-CYCLASE IN CULTURED ASTROCYTES, A BABA,H SAGA,H HASHIMOTO, JOURNAL OF NEUROCHEMISTRY, LIPPINCOTT-RAVEN PUBL, Vol. 59, p. S5-S5, 1992

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Hashimoto Hitoshi

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