ELOC変異型、TSC1/2/MTOR変異型腎細胞がんの分子生物学的および病理学的特徴

深川 彰彦, 濱 奈津子, 中村 浩実, 新井 康仁, 足立 美保子, 前島 亜希子, 松井 喜之, 中村 英二郎, 牛久 哲男, 谷内田 真一, 柴田 龍弘

腎癌研究会会報　No. 54　p. 30-30　2024/07

DNA Methylation Profiling Enables Accurate Classification of Nonductal Primary Pancreatic Neoplasms.

Anna Vera D Verschuur, Wenzel M Hackeng, Florine Westerbeke, Jamal K Benhamida, Olca Basturk, Pier Selenica, G Mihaela Raicu, I Quintus Molenaar, Hjalmar C van Santvoort, Lois A Daamen, David S Klimstra, Shinichi Yachida, Claudio Luchini, Aatur D Singhi, Christoph Geisenberger, Lodewijk A A Brosens

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association　Vol. 22　No. 6　p. 1245-1254　2024/06　Research paper (scientific journal)

Fusobacterium species are distinctly associated with patients with Lynch Syndrome colorectal cancer

Felix Salim, Sayaka Mizutani, Satoshi Shiba, Hiroyuki Takamaru, Masayoshi Yamada, Takeshi Nakajima, Tatsuo Yachida, Tomoyoshi Soga, Yutaka Saito, Shinji Fukuda, Shinichi Yachida, Takuji Yamada

iScience　Vol. 27　No. 7　p. 110181-110181　2024/06　Research paper (scientific journal)

PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas.

Tamara Cubiella, Lucía Celada, Jaime San-Juan-Guardado, Raúl Rodríguez-Aguilar, Álvaro Suárez-Priede, María Poch, Francisco Dominguez, Iván Fernández-Vega, Pedro Montero-Pavón, Mario F Fraga, Yoichiro Nakatani, So Takata, Shinichi Yachida, Nuria Valdés, María-Dolores Chiara

The Journal of pathology　Vol. 263　No. 4-5　p. 418-428　2024/05/25　Research paper (scientific journal)

Survival of Metastatic Human Papillomavirus (HPV)-Related Head and Neck Cancer Receiving Platinum-Based Triplet Induction Chemotherapy and Relevance of Circulating Tumor HPV DNA.

Hirotaka Eguchi, Yukinori Takenaka, Hidenori Tanaka, Motoyuki Suzuki, Masafumi Horie, Haruka Kanai, Yuji Seo, Kazuhiko Ogawa, Shinichi Yachida, Hidenori Inohara

Cureus　Vol. 16　No. 5　2024/05　Research paper (scientific journal)

Intestinal Bacteria Fluctuating in Early-Stage Colorectal Cancer Carcinogenesis are Associated with Diet in Healthy Adults.

Nobuhiro Narii, Ling Zha, Tomotaka Sobue, Tetsuhisa Kitamura, Masayo Komatsu, Yoshimitsu Shimomura, Satoshi Shiba, Sayaka Mizutani, Takuji Yamada, Shinichi Yachida

Nutrition and cancer　Vol. 76　No. 6　p. 1-8　2024/04/20　Research paper (scientific journal)

Association of circulating tumor HPV16DNA levels and quantitative PET parameters in patients with HPV-positive head and neck squamous cell carcinoma

Mitsuaki Tatsumi, Hidenori Tanaka, Yukinori Takenaka, Motoyuki Suzuki, Takahito Fukusumi, Hirotaka Eguchi, Tadashi Watabe, Hiroki Kato, Shinichi Yachida, Hidenori Inohara, Noriyuki Tomiyama

Scientific Reports　Vol. 14　No. 1　p. 3278-3278　2024/02/08　Research paper (scientific journal)

Patient survey on cancer genomic medicine in Japan under the national health insurance system.

Hidenori Kage, Nana Akiyama, Hyangri Chang, Aya Shinozaki-Ushiku, Mirei Ka, Junichi Kawata, Manabu Muto, Yusuke Okuma, Natsuko Okita, Katsuya Tsuchihara, Junko Kikuchi, Hidekazu Shirota, Hideyuki Hayashi, Toshio Kokuryo, Shinichi Yachida, Akira Hirasawa, Makoto Kubo, Hirotsugu Kenmotsu, Masahiko Tanabe, Tetsuo Ushiku, Kaori Muto, Yasuyuki Seto, Katsutoshi Oda

Cancer science　Vol. 115　No. 3　p. 954-962　2024/01/26　Research paper (scientific journal)

Genomic and epigenomic integrative subtypes of renal cell carcinoma in a Japanese cohort

Akihiko Fukagawa, Natsuko Hama, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Mihoko Saito-Adachi, Akiko Maeshima, Yoshiyuki Matsui, Shinichi Yachida, Tetsuo Ushiku, Tatsuhiro Shibata

Nature Communications　Vol. 14　No. 1　p. 8383-8383　2023/12/16　Research paper (scientific journal)

Metastases and treatment-resistant lineages in patient-derived cancer cells of colorectal cancer

Shiki Fujino, Norikatsu Miyoshi, Aya Ito, Rie Hayashi, Masayoshi Yasui, Chu Matsuda, Masayuki Ohue, Masafumi Horie, Shinichi Yachida, Jun Koseki, Teppei Shimamura, Tsuyoshi Hata, Takayuki Ogino, Hidekazu Takahashi, Mamoru Uemura, Tsunekazu Mizushima, Yuichiro Doki, Hidetoshi Eguchi

Communications Biology　Vol. 6　No. 1　p. 1191-1191　2023/11/24　Research paper (scientific journal)

腎細胞がんの統合的ゲノム・エピゲノム解析(Genomic and Epigenomic Integrative Subtypes of Renal Cell Carcinoma)

深川 彰彦, 濱 奈津子, 十時 泰, 中村 浩実, 新井 康仁, 足立 美保子, 前島 亜希子, 松井 喜之, 谷内田 真一, 牛久 哲男, 柴田 龍弘

日本癌学会総会記事　Vol. 82回　p. 459-459　2023/09

Cancer Stem Cells Persist Despite Cellular Damage, Emergence of the Refractory Cell Population.

Ayumi Nagae, Norikatsu Miyoshi, Shiki Fujino, Masafumi Horie, Shinichi Yachida, Masaru Sasaki, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Hidekazu Takahashi, Mamoru Uemura, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi

Annals of surgical oncology　Vol. 30　No. 11　p. 6913-6924　2023/07/31　Research paper (scientific journal)

膵癌早期診断を目指した検診システムの構築 ゲノム検診・リキッドの可能性

森實 千種, 肱岡 範, 谷内田 真一, 奥坂 拓志

膵臓　Vol. 38　No. 3　p. A162-A162　2023/07

Oncogenic structural aberration landscape in gastric cancer genomes.

Mihoko Saito-Adachi, Natsuko Hama, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Fumie Hosoda, Hirofumi Rokutan, Shinichi Yachida, Mamoru Kato, Akihiko Fukagawa, Tatsuhiro Shibata

Nature communications　Vol. 14　No. 1　p. 3688-3688　2023/06/22　Research paper (scientific journal)

Multiancestry genomic and transcriptomic analysis of gastric cancer.

Yasushi Totoki, Mihoko Saito-Adachi, Yuichi Shiraishi, Daisuke Komura, Hiromi Nakamura, Akihiro Suzuki, Kenji Tatsuno, Hirofumi Rokutan, Natsuko Hama, Shogo Yamamoto, Hanako Ono, Yasuhito Arai, Fumie Hosoda, Hiroto Katoh, Kenichi Chiba, Naoko Iida, Genta Nagae, Hiroki Ueda, Chen Shihang, Shigeki Sekine, Hiroyuki Abe, Sachiyo Nomura, Tetsuya Matsuura, Eiji Sakai, Takashi Ohshima, Yasushi Rino, Khay Guan Yeoh, Jimmy So, Kaushal Sanghvi, Richie Soong, Akihiko Fukagawa, Shinichi Yachida, Mamoru Kato, Yasuyuki Seto, Tetsuo Ushiku, Atsushi Nakajima, Hitoshi Katai, Patrick Tan, Shumpei Ishikawa, Hiroyuki Aburatani, Tatsuhiro Shibata

Nature genetics　Vol. 55　No. 4　p. 581-594　2023/04　Research paper (scientific journal)

L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis.

Sho Tabata, Yasushi Kojima, Takeharu Sakamoto, Kaori Igarashi, Ko Umetsu, Takamasa Ishikawa, Akiyoshi Hirayama, Rie Kajino-Sakamoto, Naoya Sakamoto, Ken-Ichi Yasumoto, Keiichi Okano, Yasuyuki Suzuki, Shinichi Yachida, Masahiro Aoki, Tomoyoshi Soga

Oncogene　Vol. 42　No. 16　p. 1294-1307　2023/03/06　Research paper (scientific journal)

An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma.

Masafumi Horie, Hidenori Tanaka, Masami Suzuki, Yoshihiko Sato, So Takata, Erina Takai, Naoya Miyashita, Akira Saito, Yoichiro Nakatani, Shinichi Yachida

Cancer science　Vol. 114　No. 6　p. 2596-2608　2023/02/24　Research paper (scientific journal)

Efficient and accurate KRAS genotyping using digital PCR combined with melting curve analysis for ctDNA from pancreatic cancer patients.

Junko Tanaka, Tatsuo Nakagawa, Kunio Harada, Chigusa Morizane, Hidenori Tanaka, Satoshi Shiba, Akihiro Ohba, Susumu Hijioka, Erina Takai, Shinichi Yachida, Yoshio Kamura, Takeshi Ishida, Takahide Yokoi, Chihiro Uematsu

Scientific reports　Vol. 13　No. 1　p. 3039-3039　2023/02/21　Research paper (scientific journal)

Leveraging explainable AI for gut microbiome-based colorectal cancer classification.

Ryza Rynazal, Kota Fujisawa, Hirotsugu Shiroma, Felix Salim, Sayaka Mizutani, Satoshi Shiba, Shinichi Yachida, Takuji Yamada

Genome biology　Vol. 24　No. 1　p. 21-21　2023/02/09　Research paper (scientific journal)

Clearance Profile of Circulating Tumor Human Papillomavirus DNA During Radiotherapy Predicts Clinical Outcomes in Human Papillomavirus-Related Oropharyngeal Cancer.

Hidenori Tanaka, Atsuhiko Uno, Yukinori Takenaka, Motoyuki Suzuki, Yuji Seo, Norihiko Takemoto, Takahito Fukusumi, Hirotaka Eguchi, Haruka Kanai, Masafumi Horie, Fumiaki Isohashi, Kazuhiko Ogawa, Shinichi Yachida, Hidenori Inohara

JCO precision oncology　Vol. 7　2023/02　Research paper (scientific journal)

Association Between Diet and Fusobacterium nucleatum in the Feces of Healthy Adults: A Hospital-based Cross-sectional Study.

Nobuhiro Narii, Ling Zha, Tomotaka Sobue, Tetsuhisa Kitamura, Satoshi Shiba, Sayaka Mizutani, Takuji Yamada, Shinichi Yachida

Cancer prevention research (Philadelphia, Pa.)　2023/01/30　Research paper (scientific journal)

Mediation effect of intestinal microbiota on the relationship between fiber intake and colorectal cancer.

Yoshimitsu Shimomura, Ling Zha, Sho Komukai, Nobuhiro Narii, Tomotaka Sobue, Tetsuhisa Kitamura, Satoshi Shiba, Sayaka Mizutani, Takuji Yamada, Norie Sawada, Shinichi Yachida

International journal of cancer　Vol. 152　No. 9　p. 1752-1762　2022/12/15　Research paper (scientific journal)

Association between Diet and Fusobacterium nucleatum in the Feces of Healthy Adults: A hospital-based cross-sectional study.

Nobuhiro Narii, Ling Zha, Tomotaka Sobue, Tetsuhisa Kitamura, Satoshi Shiba, Sayaka Mizutani, Takuji Yamada, Shinichi Yachida

Cancer prevention research (Philadelphia, Pa.)　2022/12/06　Research paper (scientific journal)

Proposal of a novel pipeline involving precise bronchoscopy of distal peripheral pulmonary lesions for genetic testing.

So Takata, Kotaro Miyake, Daichi Maeda, Kazue Hatake, Izumi Nagatomo, Takayuki Shiroyama, Kentaro Masuhiro, Moto Yaga, Yuya Shirai, Yuichi Mitsui, Shinichi Yachida, Atsushi Kumanogoh

Scientific reports　Vol. 12　No. 1　p. 19774-19774　2022/11/17　Research paper (scientific journal)

がん全ゲノム解析の新たな展開 腎細胞がんにおける統合的ゲノム・エピゲノム解析(Genomic and Epigenomic Attributions of Renal Cell Carcinoma)

深川 彰彦, 濱 奈津子, 十時 泰, 中村 浩美, 新井 康仁, 足立 美奈子, 細田 文恵, 前島 亜希子, 松井 喜之, 小林 佑哉, 柴 知史, 佐藤 悠佑, 小川 誠司, 谷内田 真一, 牛久 哲男, 柴田 龍弘

日本癌学会総会記事　Vol. 81回　p. CS2-2　2022/09

[Challenges in Expert Panel].

Shinichi Yachida

Gan to kagaku ryoho. Cancer & chemotherapy　Vol. 49　No. 9　p. 994-996　2022/09　Research paper (scientific journal)

[Panel Discussion - Problems in the Cancer Genomic Medicine].

Chikashi Ishioka, Manabu Muto, Shinichi Yachida, Hidekazu Shirota, Akira Hirasawa, Kiyoshi Miyagawa, Kazuto Ashizawa, Ichiro Kinoshita, Hiroshi Nishihara, Nariaki Matsuura, Akihiro Sakurai

Gan to kagaku ryoho. Cancer & chemotherapy　Vol. 49　No. 9　p. 1014-1017　2022/09　Research paper (scientific journal)

がん幹細胞による治療抵抗性細胞の再構築(Cancer stem cell reproduce treatment-resistant cells)

藤野 志季, 武田 和, 團野 克樹, 山本 慧, 東口 公哉, 野口 幸藏, 豊田 泰弘, 平尾 隆文, 岡 義雄, 堀江 真史, 谷内田 真一, 大植 雅之, 土岐 祐一郎, 江口 英利, 三吉 範克

日本癌学会総会記事　Vol. 81回　p. MS2-3　2022/09

Germline variants in cancer-predisposing genes in pancreatic cancer patients with a family history of cancer.

Takeshi Terashima, Chigusa Morizane, Mineko Ushiama, Satoshi Shiba, Hideaki Takahashi, Masafumi Ikeda, Nobumasa Mizuno, Kunihiro Tsuji, Kohichiroh Yasui, Nobuaki Azemoto, Hironaga Satake, Shogo Nomura, Shinichi Yachida, Kokichi Sugano, Junji Furuse

Japanese journal of clinical oncology　Vol. 52　No. 10　p. 1105-1114　2022/07/23　Research paper (scientific journal)

Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science.

Kentaro Inamura, Tsuyoshi Hamada, Susan Bullman, Tomotaka Ugai, Shinichi Yachida, Shuji Ogino

Gut　2022/07/12　Research paper (scientific journal)

Firmicutes in Gut Microbiota Correlate with Blood Testosterone Levels in Elderly Men.

Makoto Matsushita, Kazutoshi Fujita, Daisuke Motooka, Koji Hatano, Junya Hata, Mitsuhisa Nishimoto, Eri Banno, Kentaro Takezawa, Shinichiro Fukuhara, Hiroshi Kiuchi, Yue Pan, Toshifumi Takao, Akira Tsujimura, Shinichi Yachida, Shota Nakamura, Wataru Obara, Hirotsugu Uemura, Norio Nonomura

The world journal of men's health　Vol. 40　No. 3　p. 517-525　2022/07　Research paper (scientific journal)

Surgical Treatment for Colorectal Cancer Partially Restores Gut Microbiome and Metabolome Traits

Shiroma, H, Shiba, S, Erawijantari, P.P, Takamaru, H, Yamada, M, Sakamoto, T, Kanemitsu, Y, Mizutani, S, Soga, T, Saito, Y, Shibata, T, Fukuda, S, Yachida, S, Yamada, T

mSystems　Vol. 7　No. 2　2022/04/26　Research paper (scientific journal)

An efficient procedure for the recovery of DNA from formalin-fixed paraffin-embedded tissue sections.

Utako Oba, Kenichi Kohashi, Yuhei Sangatsuda, Yoshinao Oda, Koh-Hei Sonoda, Shouichi Ohga, Koji Yoshimoto, Yasuhito Arai, Shinichi Yachida, Tatsuhiro Shibata, Takashi Ito, Fumihito Miura

Biology methods & protocols　Vol. 7　No. 1　2022　Research paper (scientific journal)

Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System.

Shinichi Yachida, Yasushi Totoki, Michael Noe, Yoichiro Nakatani, Masafumi Horie, Kenta Kawasaki, Hiromi Nakamura, Mihoko Saito-Adachi, Masami Suzuki, Erina Takai, Natsuko Hama, Ryota Higuchi, Seiko Hirono, Satoshi Shiba, Mamoru Kato, Eisaku Furukawa, Yasuhito Arai, Hirofumi Rokutan, Taiki Hashimoto, Shuichi Mitsunaga, Mitsuro Kanda, Hidenori Tanaka, So Takata, Ayaka Shimomura, Minoru Oshima, Wenzel M Hackeng, Tomoyuki Okumura, Keiichi Okano, Masakazu Yamamoto, Hiroki Yamaue, Chigusa Morizane, Koji Arihiro, Toru Furukawa, Toshiro Sato, Tohru Kiyono, Lodewijk A A Brosens, Laura D Wood, Ralph H Hruban, Tatsuhiro Shibata

Cancer discovery　Vol. 12　No. 3　p. 692-711　2021/12/08　Research paper (scientific journal)

Performance of Oral HPV DNA , Oral HPV mRNA , and Circulating Tumor HPV DNA in the Detection of HPV‐Related Oropharyngeal Cancer and Cancer of Unknown Primary

Hidenori Tanaka, Motoyuki Suzuki, Norihiko Takemoto, Takahito Fukusumi, Hirotaka Eguchi, Erina Takai, Haruka Kanai, Mitsuaki Tatsumi, Masafumi Horie, Yukinori Takenaka, Shinichi Yachida, Hidenori Inohara

International Journal of Cancer　Vol. 150　No. 1　p. 174-186　2021/09/06　Research paper (scientific journal)

Clonal dynamics of circulating tumor DNA during immune checkpoint blockade therapy for melanoma.

Erina Takai, Wataru Omata, Yasushi Totoki, Hiromi Nakamura, Satoshi Shiba, Akira Takahashi, Kenjiro Namikawa, Taisuke Mori, Naoya Yamazaki, Tatsuhiro Shibata, Shinichi Yachida

Cancer science　2021/09/03　Research paper (scientific journal)

The gut microbiota associated with high-Gleason prostate cancer.

Makoto Matsushita, Kazutoshi Fujita, Daisuke Motooka, Koji Hatano, Shota Fukae, Norihiko Kawamura, Eisuke Tomiyama, Yujiro Hayashi, Eri Banno, Tetsuya Takao, Shingo Takada, Shinichi Yachida, Hirotsugu Uemura, Shota Nakamura, Norio Nonomura

Cancer science　Vol. 112　No. 8　p. 3125-3135　2021/05/29　Research paper (scientific journal)

Clinical Utility of Next-Generation Sequencing-Based Panel Testing under the Universal Health-Care System in Japan: A Retrospective Analysis at a Single University Hospital.

Chiaki Inagaki, Daichi Maeda, Kazue Hatake, Yuki Sato, Kae Hashimoto, Daisuke Sakai, Shinichi Yachida, Norio Nonomura, Taroh Satoh

Cancers　Vol. 13　No. 5　2021/03/05　Research paper (scientific journal)

Circulating tumor HPV DNA complements PET-CT in guiding management after radiotherapy in HPV-related squamous cell carcinoma of the head and neck.

Hidenori Tanaka, Norihiko Takemoto, Masafumi Horie, Erina Takai, Takahito Fukusumi, Motoyuki Suzuki, Hirotaka Eguchi, Sho Komukai, Mitsuaki Tatsumi, Fumiaki Isohashi, Kazuhiko Ogawa, Shinichi Yachida, Hidenori Inohara

International journal of cancer　Vol. 148　No. 4　p. 995-1005　2021/02/15　Research paper (scientific journal)

Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1).

Yoichi Naito, Hiroyuki Aburatani, Toraji Amano, Eishi Baba, Toru Furukawa, Tetsu Hayashida, Eiso Hiyama, Sadakatsu Ikeda, Masashi Kanai, Motohiro Kato, Ichiro Kinoshita, Naomi Kiyota, Takashi Kohno, Shinji Kohsaka, Keigo Komine, Itaru Matsumura, Yuji Miura, Yoshiaki Nakamura, Atsushi Natsume, Kazuto Nishio, Katsutoshi Oda, Naoyuki Oda, Natsuko Okita, Kumiko Oseto, Kuniko Sunami, Hideaki Takahashi, Masayuki Takeda, Shimon Tashiro, Shinichi Toyooka, Hideki Ueno, Shinichi Yachida, Takayuki Yoshino, Katsuya Tsuchihara

International journal of clinical oncology　Vol. 26　No. 2　p. 233-283　2021/02　Research paper (scientific journal)

E74-Like Factor 3 Is a Key Regulator of Epithelial Integrity and Immune Response Genes in Biliary Tract Cancer.

Masami Suzuki, Mihoko Saito-Adachi, Yasuhito Arai, Yuko Fujiwara, Erina Takai, Shinsuke Shibata, Masahide Seki, Hirofumi Rokutan, Daichi Maeda, Masafumi Horie, Yutaka Suzuki, Tatsuhiro Shibata, Tohru Kiyono, Shinichi Yachida

Cancer research　Vol. 81　No. 2　p. 489-500　2021/01/15　Research paper (scientific journal)

Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H.

Yuki Shibayama, Kazuo Takahashi, Hisateru Yamaguchi, Jun Yasuda, Daisuke Yamazaki, Asadur Rahman, Takayuki Fujimori, Yoshihide Fujisawa, Shinji Takai, Toru Furukawa, Tsutomu Nakagawa, Hiroyuki Ohsaki, Hideki Kobara, Jing Hao Wong, Tsutomu Masaki, Yukio Yuzawa, Hideyasu Kiyomoto, Shinichi Yachida, Akihiro Fujimoto, Akira Nishiyama

Communications biology　Vol. 3　No. 1　p. 724-724　2020/11/27　Research paper (scientific journal)

Detection of MEAF6-PHF1 translocation in an endometrial stromal nodule.

Yusuke Nomura, Daisuke Tamura, Masafumi Horie, Masakazu Sato, Shinya Sasaki, Yohei Yamamoto, Yukitsugu Kudo-Asabe, Michinobu Umakoshi, Kei Koyama, Kenichi Makino, Shinogu Takashima, Kazuhiro Imai, Yoshihiro Minamiya, Satoru Munakata, Shinichi Yachida, Yukihiro Terada, Akiteru Goto, Daichi Maeda

Genes, chromosomes & cancer　2020/08/20　Research paper (scientific journal)

Genomic characterization of malignant progression in neoplastic pancreatic cysts.

Michaël Noë, Noushin Niknafs, Catherine G Fischer, Wenzel M Hackeng, Violeta Beleva Guthrie, Waki Hosoda, Marija Debeljak, Eniko Papp, Vilmos Adleff, James R White, Claudio Luchini, Antonio Pea, Aldo Scarpa, Giovanni Butturini, Giuseppe Zamboni, Paola Castelli, Seung-Mo Hong, Shinichi Yachida, Nobuyoshi Hiraoka, Anthony J Gill, Jaswinder S Samra, G Johan A Offerhaus, Anne Hoorens, Joanne Verheij, Casper Jansen, N Volkan Adsay, Wei Jiang, Jordan Winter, Jorge Albores-Saavedra, Benoit Terris, Elizabeth D Thompson, Nicholas J Roberts, Ralph H Hruban, Rachel Karchin, Robert B Scharpf, Lodewijk A A Brosens, Victor E Velculescu, Laura D Wood

Nature communications　Vol. 11　No. 1　p. 4085-4085　2020/08/14　Research paper (scientific journal)

がんゲノム時代における外科の役割

舟木 壮一郎, 福井 絵里子, 狩野 孝, 大瀬 尚子, 南 正人, 新谷 康, 長友 泉, 武田 吉人, 熊ノ郷 淳, 谷内田 真一

日本外科学会定期学術集会抄録集　Vol. 120回　p. SF-1　2020/08

【遺伝性腫瘍とゲノム医療を学ぶ】遺伝性腫瘍 家族性膵癌

高折 恭一, 森実 千種, 北野 雅之, 肱岡 範, 谷内田 真一, 松林 宏行, 和田 慶太, 鳥嶋 雅子, 小杉 眞司, 川口 喬久, 増井 俊彦

臨床外科　Vol. 75　No. 8　p. 927-930　2020/08

Influence of gastrectomy for gastric cancer treatment on faecal microbiome and metabolome profiles.

Pande Putu Erawijantari, Sayaka Mizutani, Hirotsugu Shiroma, Satoshi Shiba, Takeshi Nakajima, Taku Sakamoto, Yutaka Saito, Shinji Fukuda, Shinichi Yachida, Takuji Yamada

Gut　Vol. 69　No. 8　p. 1404-1415　2020/08　Research paper (scientific journal)

Feasibility study of nivolumab as neoadjuvant chemotherapy for locally esophageal carcinoma: FRONTiER (JCOG1804E).

Shun Yamamoto, Ken Kato, Hiroyuki Daiko, Takashi Kojima, Hiroki Hara, Tetsuya Abe, Yasuhiro Tsubosa, Kengo Nagashima, Kazunori Aoki, Yukihiro Mizoguchi, Shigehisa Kitano, Shinichi Yachida, Satoshi Shiba, Yuko Kitagawa

Future oncology (London, England)　Vol. 16　No. 19　p. 1351-1357　2020/07　Research paper (scientific journal)

当院での外科切除サンプルを用いたがん遺伝子パネル検査について

舟木 壮一郎, 福井 絵里子, 狩野 孝, 大瀬 尚子, 南 正人, 新谷 康, 谷内田 真一

肺癌　Vol. 60　No. 2　p. 153-153　2020/04

Significance of the gut microbiome in multistep colorectal carcinogenesis.

Sayaka Mizutani, Takuji Yamada, Shinichi Yachida

Cancer science　Vol. 111　No. 3　p. 766-773　2020/03　Research paper (scientific journal)

Post-mortem Plasma Cell-Free DNA Sequencing: Proof-of-Concept Study for the "Liquid Autopsy".

Erina Takai, Daichi Maeda, Zhuo Li, Yukitsugu Kudo-Asabe, Yasushi Totoki, Hiromi Nakamura, Akiko Nakamura, Rumi Nakamura, Misato Kirikawa, Yukinobu Ito, Makoto Yoshida, Takamitsu Inoue, Tomonori Habuchi, Shohei Ikoma, Hiroto Katoh, Mamoru Kato, Tatsuhiro Shibata, Shumpei Ishikawa, Shinichi Yachida, Akiteru Goto

Scientific reports　Vol. 10　No. 1　p. 2120-2120　2020/02/07　Research paper (scientific journal)

Pan-cancer analysis of whole genomes.

Nature　Vol. 578　No. 7793　p. 82-93　2020/02　Research paper (scientific journal)

糞便メタゲノムおよびメタボローム解析を用いた大腸がんの多段階発がんに伴う腸内環境の変化

水谷 紗弥佳, 谷内田 真一, 城間 博紹, 柴 知史, 山田 拓司

日本細菌学雑誌　Vol. 75　No. 1　p. 143-143　2020/01

Surveillance for the early diagnosis of familial pancreatic cancer (Expert consensus)

北野雅之, 森実千種, 肱岡範, 松林宏行, 蘆田玲子, 池浦司, 伊藤鉄英, 神澤輝実, 川口喬久, 河邉顕, 小杉眞司, 児玉裕三, 清水京子, 高橋秀明, 谷内田真一, 寺島健志, 鳥嶋雅子, 花田敬士, 古川徹, 古川正幸, 古瀬純司, 真口宏介, 眞島喜幸, 水野伸匡, 水間正道, 水本雅己, 吉田岳市, 和田慶太, 高折恭一

膵臓(Web)　Vol. 35　No. 4　2020

Surveillance for the early diagnosis of familial pancreatic cancer (Expert consensus)

KITANO Masayuki, KAWABE Ken, KOSUGI Shinji, KODAMA Yuzo, SHIMIZU Kyoko, TAKAHASHI Hideaki, YACHIDA Shinichi, TERASHIMA Takeshi, TORISHIMA Masako, HANADA Keiji, FURUKAWA Toru, MORIZANE Chigusa, FURUKAWA Masayuki, FURUSE Junji, MAGUCHI Hiroyuki, MAJIMA Yoshiyuki, MIZUNO Nobumasa, MIZUMA Masamichi, MIZUMOTO Masaki, YOSHIDA Takeichi, WADA Keita, TAKAORI Kyoichi, HIJIOKA Susumu, MATSUBAYASHI Hiroyuki, ASHIDA Reiko, IKEURA Tsukasa, ITO Tetsuhide, KAMISAWA Terumi, KAWAGUCHI Takahisa

Suizo　Vol. 35　No. 4　p. 322-330　2020

Circulating tumor DNA as a prognostic indicator in resectable pancreatic ductal adenocarcinoma: A systematic review and meta-analysis.

Lee JS, Rhee TM, Pietrasz D, Bachet JB, Laurent-Puig P, Kong SY, Takai E, Yachida S, Shibata T, Lee JW, Park HC, Zang DY, Jeon K, Lee J, Kim M, Kim HS, Kang HJ, Lee YK

Scientific reports　Vol. 9　No. 1　2019/11/18

Germline mutations in cancer-predisposition genes in patients with biliary tract cancer.

Takeshi Terashima, Kumiko Umemoto, Hideaki Takahashi, Hiroko Hosoi, Erina Takai, Shunsuke Kondo, Yasunari Sakamoto, Shuichi Mitsunaga, Izumi Ohno, Yusuke Hashimoto, Mitsuhito Sasaki, Masafumi Ikeda, Kazuaki Shimada, Shuichi Kaneko, Shinichi Yachida, Kokichi Sugano, Takuji Okusaka, Chigusa Morizane

Oncotarget　Vol. 10　No. 57　p. 5949-5957　2019/10/15　Research paper (scientific journal)

Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2.

Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, Ando R, Kondo A, Anwar M, Tsuchida R, Hino S, Sakamoto A, Igarashi K, Saitoh K, Kato K, Endo K, Yamano S, Kanki Y, Matsumura Y, Minami T, Tanaka T, Anai M, Wada Y, Wanibuchi H, Hayashi M, Hamada A, Yoshida M, Yachida S, Nakao M, Sakai J, Aburatani H, Shibuya M, Hanada K, Miyano S, Soga T, Kodama T

Cell reports　Vol. 29　No. 1　p. 89-103.e7　2019/10　Research paper (scientific journal)

Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation.

Thomas AM, Manghi P, Asnicar F, Pasolli E, Armanini F, Zolfo M, Beghini F, Manara S, Karcher N, Pozzi C, Gandini S, Serrano D, Tarallo S, Francavilla A, Gallo G, Trompetto M, Ferrero G, Mizutani S, Shiroma H, Shiba S, Shibata T, Yachida S, Yamada T, Wirbel J, Schrotz-King P, Ulrich CM, Brenner H, Arumugam M, Bork P, Zeller G, Cordero F, Dias-Neto E, Setubal JC, Tett A, Pardini B, Rescigno M, Waldron L, Naccarati A, Segata N

Nature medicine　Vol. 25　No. 12　p. 1948-1948　2019/10

Gallbladder cancer harboring ERBB2 mutation on the primary and metastatic site: A case report.

Chiaki Inagaki, Daichi Maeda, Akie Kimura, Toru Otsuru, Yoshifumi Iwagami, Naohiro Nishida, Daisuke Sakai, Ryo Shitotsuki, Shinichi Yachida, Yuichiro Doki, Taroh Satoh

World journal of gastrointestinal oncology　Vol. 11　No. 9　p. 761-767　2019/09/15

Correction: Establishment of preclinical chemotherapy models for gastroenteropancreatic neuroendocrine carcinoma.

Akihiro Ohmoto, Masami Suzuki, Erina Takai, Hirofumi Rokutan, Yuko Fujiwara, Chigusa Morizane, Kazuyoshi Yanagihara, Tatsuhiro Shibata, Shinichi Yachida

Oncotarget　Vol. 10　No. 52　p. 5494-5494　2019/09/10

分化型の胃粘膜内腫瘍における初期体細胞変異(Initial mutations in well-differentiated intramucosal neoplasias of the stomach)

六反 啓文, 阿部 浩幸, 中村 浩実, 牛久 哲男, 細田 文恵, 谷内田 真一, 辻 陽介, 藤城 光弘, 小池 和彦, 十時 泰, 深山 正久, 柴田 龍弘

日本癌学会総会記事　Vol. 78回　p. J-2027　2019/09

A multimodality test to guide the management of patients with a pancreatic cyst.

Springer S, Masica DL, Dal Molin M, Douville C, Thoburn CJ, Afsari B, Li L, Cohen JD, Thompson E, Allen PJ, Klimstra DS, Schattner MA, Schmidt CM, Yip-Schneider M, Simpson RE, Fernandez-Del Castillo C, Mino-Kenudson M, Brugge W, Brand RE, Singhi AD, Scarpa A, Lawlor R, Salvia R, Zamboni G, Hong SM, Hwang DW, Jang JY, Kwon W, Swan N, Geoghegan J, Falconi M, Crippa S, Doglioni C, Paulino J, Schulick RD, Edil BH, Park W, Yachida S, Hijioka S, van Hooft J, He J, Weiss MJ, Burkhart R, Makary M, Canto MI, Goggins MG, Ptak J, Dobbyn L, Schaefer J, Sillman N, Popoli M, Klein AP, Tomasetti C, Karchin R, Papadopoulos N, Kinzler KW, Vogelstein B, Wolfgang CL, Hruban RH, Lennon AM

Science translational medicine　Vol. 11　No. 501　2019/07

Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer.

Shinichi Yachida, Sayaka Mizutani, Hirotsugu Shiroma, Satoshi Shiba, Takeshi Nakajima, Taku Sakamoto, Hikaru Watanabe, Keigo Masuda, Yuichiro Nishimoto, Masaru Kubo, Fumie Hosoda, Hirofumi Rokutan, Minori Matsumoto, Hiroyuki Takamaru, Masayoshi Yamada, Takahisa Matsuda, Motoki Iwasaki, Taiki Yamaji, Tatsuo Yachida, Tomoyoshi Soga, Ken Kurokawa, Atsushi Toyoda, Yoshitoshi Ogura, Tetsuya Hayashi, Masanori Hatakeyama, Hitoshi Nakagama, Yutaka Saito, Shinji Fukuda, Tatsuhiro Shibata, Takuji Yamada

Nature medicine　Vol. 25　No. 6　p. 968-976　2019/06　Research paper (scientific journal)

Initial and crucial genetic events in intestinal-type gastric intramucosal neoplasia

Hirofumi Rokutan, Hiroyuki Abe, Hiromi Nakamura, Tetsuo Ushiku, Erika Arakawa, Fumie Hosoda, Shinichi Yachida, Yosuke Tsuji, Mitsuhiro Fujishiro, Kazuhiko Koike, Yasushi Totoki, Masashi Fukayama, Tatsuhiro Shibata

Journal of Pathology　Vol. 247　No. 4　p. 494-504　2019/04/01　Research paper (scientific journal)

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.

Wirbel J, Pyl PT, Kartal E, Zych K, Kashani A, Milanese A, Fleck JS, Voigt AY, Palleja A, Ponnudurai R, Sunagawa S, Coelho LP, Schrotz-King P, Vogtmann E, Habermann N, Niméus E, Thomas AM, Manghi P, Gandini S, Serrano D, Mizutani S, Shiroma H, Shiba S, Shibata T, Yachida S, Yamada T, Waldron L, Naccarati A, Segata N, Sinha R, Ulrich CM, Brenner H, Arumugam M, Bork P, Zeller G

Nature medicine　Vol. 25　No. 4　p. 679-689　2019/04　Research paper (scientific journal)

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation.

Thomas AM, Manghi P, Asnicar F, Pasolli E, Armanini F, Zolfo M, Beghini F, Manara S, Karcher N, Pozzi C, Gandini S, Serrano D, Tarallo S, Francavilla A, Gallo G, Trompetto M, Ferrero G, Mizutani S, Shiroma H, Shiba S, Shibata T, Yachida S, Yamada T, Wirbel J, Schrotz-King P, Ulrich CM, Brenner H, Arumugam M, Bork P, Zeller G, Cordero F, Dias-Neto E, Setubal JC, Tett A, Pardini B, Rescigno M, Waldron L, Naccarati A, Segata N

Nature medicine　Vol. 25　No. 4　p. 667-678　2019/04　Research paper (scientific journal)

Genomic Features and Clinical Management of Patients with Hereditary Pancreatic Cancer Syndromes and Familial Pancreatic Cancer.

Akihiro Ohmoto, Shinichi Yachida, Chigusa Morizane

International journal of molecular sciences　Vol. 20　No. 3　2019/01/29　Research paper (scientific journal)

Perineural Invasion is a Strong Prognostic Moderator in Ampulla of Vater Carcinoma: A Meta-analysis

Claudio Luchini, Nicola Veronese, Alessia Nottegar, Giulio Riva, Camilla Pilati, Andrea Mafficini, Brendon Stubbs, Michele Simbolo, Aldo Mombello, Vincenzo Corbo, Liang Cheng, Shinichi Yachida, Laura D. Wood, Rita T. Lawlor, Roberto Salvia, Aldo Scarpa

Pancreas　Vol. 48　p. 70-76　2019/01/01

Germline variants in pancreatic cancer patients with a personal or family history of cancer fulfilling the revised Bethesda guidelines.

Akihiro Ohmoto, Chigusa Morizane, Emi Kubo, Erina Takai, Hiroko Hosoi, Yasunari Sakamoto, Shunsuke Kondo, Hideki Ueno, Kazuaki Shimada, Shinichi Yachida, Takuji Okusaka

Journal of gastroenterology　Vol. 53　No. 10　p. 1159-1167　2018/10　Research paper (scientific journal)

【ここまで来た!膵癌の早期診断】膵癌早期診断における家族性膵癌登録の役割

高折 恭一, 森実 千種, 北野 雅之, 肱岡 範, 谷内田 真一, 岡崎 和一

胆と膵　Vol. 39　No. 9　p. 773-776　2018/09

Precancerous neoplastic cells can move through the pancreatic ductal system.

Makohon-Moore AP, Matsukuma K, Zhang M, Reiter JG, Gerold JM, Jiao Y, Sikkema L, Attiyeh MA, Yachida S, Sandone C, Hruban RH, Klimstra DS, Papadopoulos N, Nowak MA, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA

Nature　Vol. 561　No. 7722　p. 201-205　2018/09

Establishment of preclinical chemotherapy models for gastroenteropancreatic neuroendocrine carcinoma.

Akihiro Ohmoto, Masami Suzuki, Erina Takai, Hirofumi Rokutan, Yuko Fujiwara, Chigusa Morizane, Kazuyoshi Yanagihara, Tatsuhiro Shibata, Shinichi Yachida

Oncotarget　Vol. 9　No. 30　p. 21086-21099　2018/04/20　Research paper (scientific journal)

屍体血中遊離DNA解析による癌の不均一性の評価 Liquid autopsyの提唱

前田 大地, 高井 英里奈, 谷内田 真一, 後藤 明輝

日本病理学会会誌　Vol. 107　No. 1　p. 292-292　2018/04

Clinicopathological features of early pancreatic cancers and pre-invasive lesions in elderly patients: an autopsy study

Matsuda Yoko, Mino-Kenuds Mari, Yachida Shinichi, Furukawa Toru, Takubo Kaiyo, Ishiwata Toshiyuki, Kimura Wataru, Arai Tomio

CANCER SCIENCE　Vol. 109　2018/01

Highly recurrent H3F3A mutations with additional epigenetic regulator alterations in giant cell tumor of bone

Koichi Ogura, Fumie Hosoda, Hiromi Nakamura, Natsuko Hama, Yasushi Totoki, Akihiko Yoshida, Shoko Ohashi, Hirofumi Rokutan, Erina Takai, Shinichi Yachida, Akira Kawai, Sakae Tanaka, Tatsuhiro Shibata

GENES CHROMOSOMES & CANCER　Vol. 56　No. 10　p. 711-718　2017/10　Research paper (scientific journal)

Strong antitumor efficacy of a pancreatic tumor-targeting oncolytic adenovirus for neuroendocrine tumors

Yuki Yamamoto, Masaki Nagasato, Yosei Rin, Marina Henmi, Yoshinori Ino, Shinichi Yachida, Rieko Ohki, Nobuyoshi Hiraoka, Masatoshi Tagawa, Kazunori Aoki

CANCER MEDICINE　Vol. 6　No. 10　p. 2385-2397　2017/10　Research paper (scientific journal)

病理解剖症例における早期膵癌および非浸潤病変の臨床病理学的特徴の検討

松田 陽子, 三野 真理, Kenuds, 谷内田 真一, 古川 徹, 田久保 海誉, 石渡 俊行, 木村 理, 新井 冨生

日本癌学会総会記事　Vol. 76回　p. P-2281　2017/09

Cardiac intimal sarcoma with PDGFR beta mutation and co-amplification of PDGFR alpha and MDM2: an autopsy case analyzed by whole-exome sequencing

Yukinobu Ito, Daichi Maeda, Makoto Yoshida, Akihiko Yoshida, Yukitsugu Kudo-Asabe, Hiroshi Nanjyo, Chikako Izumi, Fumio Yamamoto, Masahiro Inoue, Hiroyuki Shibata, Hiroto Katoh, Shumpei Ishikawa, Hiromi Nakamura, Yasushi Totoki, Tatsuhiro Shibata, Shinichi Yachida, Akiteru Goto

VIRCHOWS ARCHIV　Vol. 471　No. 3　p. 423-428　2017/09　Research paper (scientific journal)

Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC

Kiyotoshi Satoh, Shinichi Yachida, Masahiro Sugimoto, Minoru Oshima, Toshitaka Nakagawa, Shintaro Akamoto, Sho Tabata, Kaori Saitoh, Keiko Kato, Saya Sato, Kaori Igarashi, Yumi Aizawa, Rie Kajino-Sakamoto, Yasushi Kojima, Teruaki Fujishita, Ayame Enomoto, Akiyoshi Hirayama, Takamasa Ishikawa, Makoto Mark Taketo, Yoshio Kushida, Reiji Haba, Keiichi Okano, Masaru Tomita, Yasuyuki Suzuki, Shinji Fukuda, Masahiro Aoki, Tomoyoshi Soga

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 114　No. 37　p. E7697-E7706　2017/09　Research paper (scientific journal)

Liquid biopsy for early detection of pancreatic cancer

Erina Takai, Shinichi Yachida

Innovation of Diagnosis and Treatment for Pancreatic Cancer　p. 59-68　2017/07/19

Personalized Management of Pancreatic Ductal Adenocarcinoma Patients through Computational Modeling

Kimiyo N. Yamamoto, Shinichi Yachida, Akira Nakamura, Atsushi Niida, Minoru Oshima, Subhajyoti De, Lauren M. Rosati, Joseph M. Herman, Christine A. Iacobuzio-Donahue, Hiroshi Haeno

CANCER RESEARCH　Vol. 77　No. 12　p. 3325-3335　2017/06　Research paper (scientific journal)

The Prevalence and Clinicopathological Characteristics of High-Grade Pancreatic Intraepithelial Neoplasia Autopsy Study Evaluating the Entire Pancreatic Parenchyma

Yoko Matsuda, Toru Furukawa, Shinichi Yachida, Makoto Nishimura, Atsuko Seki, Keisuke Nonaka, Junko Aida, Kaiyo Takubo, Toshiyuki Ishiwata, Wataru Kimura, Tomio Arai, Mari Mino-Kenudson

PANCREAS　Vol. 46　No. 5　p. 658-664　2017/05　Research paper (scientific journal)

Correction: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.

Ryutaro Uchi, Yusuke Takahashi, Atsushi Niida, Teppei Shimamura, Hidenari Hirata, Keishi Sugimachi, Genta Sawada, Takeshi Iwaya, Junji Kurashige, Yoshiaki Shinden, Tomohiro Iguchi, Hidetoshi Eguchi, Kenichi Chiba, Yuichi Shiraishi, Genta Nagae, Kenichi Yoshida, Yasunobu Nagata, Hiroshi Haeno, Hirofumi Yamamoto, Hideshi Ishii, Yuichiro Doki, Hisae Iinuma, Shin Sasaki, Satoshi Nagayama, Kazutaka Yamada, Shinichi Yachida, Mamoru Kato, Tatsuhiro Shibata, Eiji Oki, Hiroshi Saeki, Ken Shirabe, Yoshinao Oda, Yoshihiko Maehara, Shizuo Komune, Masaki Mori, Yutaka Suzuki, Ken Yamamoto, Hiroyuki Aburatani, Seishi Ogawa, Satoru Miyano, Koshi Mimori

PLoS genetics　Vol. 13　No. 5　2017/05

Familial pancreatic cancer: Concept, management and issues

Hiroyuki Matsubayashi, Kyoichi Takaori, Chigusa Morizane, Hiroyuki Maguchi, Masamichi Mizuma, Hideaki Takahashi, Keita Wada, Hiroko Hosoi, Shinichi Yachida, Masami Suzuki, Risa Usui, Toru Furukawa, Junji Furuse, Takamitsu Sato, Makoto Ueno, Yoshimi Kiyozumi, Susumu Hijioka, Nobumasa Mizuno, Takeshi Terashima, Masaki Mizumoto, Yuzo Kodama, Masako Torishima, Takahisa Kawaguchi, Reiko Ashida, Masayuki Kitano, Keiji Hanada, Masayuki Furukawa, Ken Kawabe, Yoshiyuki Majima, Toru Shimosegawa

WORLD JOURNAL OF GASTROENTEROLOGY　Vol. 23　No. 6　p. 935-948　2017/02

Current status of poly(ADP-ribose) polymerase inhibitors and future directions

Akihiro Ohmoto, Shinichi Yachida

ONCOTARGETS AND THERAPY　Vol. 10　p. 5195-5208　2017

High-Grade PanIN/Carcinoma In Situ of the Pancreas Associated With Cystic Changes and Fibrosis

Y. Matsuda, T. Furukawa, S. Yachida, M. Nishimura, A. Seki, K. Nonaka, J. Aida, K. Takubo, T. Ishiwata, W. Kimura, T. Arai, M. Mino-Kenudson

PANCREAS　Vol. 45　No. 10　p. 1523-1524　2016/11

Germline mutations in Japanese familial pancreatic cancer patients

Erina Takai, Shinichi Yachida, Kyoko Shimizu, Junji Furuse, Emi Kubo, Akihiro Ohmoto, Masami Suzuki, Ralph H. Hruban, Takuji Okusaka, Chigusa Morizane, Toru Furukawa

ONCOTARGET　Vol. 7　No. 45　p. 74227-74235　2016/11　Research paper (scientific journal)

Different Prognostic Roles of Tumor Suppressor Gene BAP1 in Cancer: A Systematic Review with Meta-Analysis

Claudio Luchini, Nicola Veronese, Shinichi Yachida, Liang Cheng, Alessia Nottegar, Brendon Stubbs, Marco Solmi, Paola Capelli, Antonio Pea, Mattia Barbareschi, Matteo Fassan, Laura Dwood, Aldo Scarpa

GENES CHROMOSOMES & CANCER　Vol. 55　No. 10　p. 741-749　2016/10

Comprehensive mutation profiling of mucinous gastric carcinoma

Hirofumi Rokutan, Fumie Hosoda, Natsuko Hama, Hiromi Nakamura, Yasushi Totoki, Eisaku Furukawa, Erika Arakawa, Shoko Ohashi, Tomoko Urushidate, Hironori Satoh, Hiroko Shimizu, Keiko Igarashi, Shinichi Yachida, Hitoshi Katai, Hirokazu Taniguchi, Masashi Fukayama, Tatsuhiro Shibata

JOURNAL OF PATHOLOGY　Vol. 240　No. 2　p. 137-148　2016/10　Research paper (scientific journal)

Circulating tumor DNA as a liquid biopsy target for detection of pancreatic cancer

Erina Takai, Shinichi Yachida

WORLD JOURNAL OF GASTROENTEROLOGY　Vol. 22　No. 38　p. 8480-8488　2016/10

High stability of faecal microbiome composition in guanidine thiocyanate solution at room temperature and robustness during colonoscopy

Yuichiro Nishimoto, Sayaka Mizutani, Takeshi Nakajima, Fumie Hosoda, Hikaru Watanabe, Yutaka Saito, Tatsuhiro Shibata, Shinichi Yachida, Takuji Yamada

GUT　Vol. 65　No. 9　p. 1574-+　2016/09　Research paper (scientific journal)

Japanese familial pancreatic cancer registry by Japan Pancreas Society

Chigusa Morizane, Takahisa Kawaguchi, Masayuki Kitano, Susumu Hijioka, Shinichi Yachida, Masako Torishima, Risa Usui, Hiroko Hosoi, Masami Suzuki, Kyoichi Takaori

Pancreatology　Vol. 16　No. 4　2016/08　Research paper (scientific journal)

Clinicopathologic Features and Germline Sequence Variants in Young Patients (<= 40 Years Old) With Pancreatic Ductal Adenocarcinoma

Akihiro Ohmoto, Shinichi Yachida, Emi Kubo, Erina Takai, Masami Suzuki, Kazuaki Shimada, Takuji Okusaka, Chigusa Morizane

PANCREAS　Vol. 45　No. 7　p. 1056-1061　2016/08　Research paper (scientific journal)

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population

Genta Sawada, Atsushi Niida, Ryutaro Uchi, Hidenari Hirata, Teppei Shimamura, Yutaka Suzuki, Yuichi Shiraishi, Kenichi Chiba, Seiya Imoto, Yusuke Takahashi, Takeshi Iwaya, Tomoya Sudo, Tomoatsu Hayashi, Hiroki Takai, Yoshihiro Kawasaki, Takashi Matsukawa, Hidetoshi Eguchi, Keishi Sugimachi, Fumiaki Tanaka, Hiromichi Suzuki, Ken Yamamoto, Hideshi Ishii, Makiko Shimizu, Hiroshi Yamazaki, Makoto Yamazaki, Yuji Tachimori, Yoshiaki Kajiyama, Shoji Natsugoe, Hiromasa Fujita, Kenichi Mafune, Yoichi Tanaka, David P. Kelsell, Claire A. Scott, Shoji Tsuji, Shinichi Yachida, Tatsuhiro Shibata, Sumio Sugano, Yuichiro Doki, Tetsu Akiyama, Hiroyuki Aburatani, Seishi Ogawa, Satoru Miyano, Masaki Mori, Koshi Mimori

GASTROENTEROLOGY　Vol. 150　No. 5　p. 1171-1182　2016/05　Research paper (scientific journal)

Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

Ryutaro Uchi, Yusuke Takahashi, Atsushi Niida, Teppei Shimamura, Hidenari Hirata, Keishi Sugimachi, Genta Sawada, Takeshi Iwaya, Junji Kurashige, Yoshiaki Shinden, Tomohiro Iguchi, Hidetoshi Eguchi, Kenichi Chiba, Yuichi Shiraishi, Genta Nagae, Kenichi Yoshida, Yasunobu Nagata, Hiroshi Haeno, Hirofumi Yamamoto, Hideshi Ishii, Yuichiro Doki, Hisae Iinuma, Shin Sasaki, Satoshi Nagayama, Kazutaka Yamada, Shinichi Yachida, Mamoru Kato, Tatsuhiro Shibata, Eiji Oki, Hiroshi Saeki, Ken Shirabe, Yoshinao Oda, Yoshihiko Maehara, Shizuo Komune, Masaki Mori, Yutaka Suzuki, Ken Yamamoto, Hiroyuki Aburatani, Seishi Ogawa, Satoru Miyano, Koshi Mimori

PLOS GENETICS　Vol. 12　No. 2　2016/02　Research paper (scientific journal)

Clinicopathological Features of 15 Occult and 178 Clinical Pancreatic Ductal Adenocarcinomas in 8339 Autopsied Elderly Patients

Yoko Matsuda, Toshiyuki Ishiwata, Shinichi Yachida, Akemi Suzuki, Yuri Hamashima, Hideki Hamayasu, Hisashi Yoshimura, Naoko Honma, Junko Aida, Kaiyo Takubo, Tomio Arai

PANCREAS　Vol. 45　No. 2　p. 234-240　2016/02　Research paper (scientific journal)

Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma

Shinichi Yachida, Laura D. Wood, Masami Suzuki, Erina Takai, Yasushi Totoki, Mamoru Kato, Claudio Luchini, Yasuhito Arai, Hiromi Nakamura, Natsuko Hama, Asmaa Elzawahry, Fumie Hosoda, Tomoki Shirota, Nobuhiko Morimoto, Kunio Hori, Jun Funazaki, Hikaru Tanaka, Chigusa Morizane, Takuji Okusaka, Satoshi Nara, Kazuaki Shimada, Nobuyoshi Hiraoka, Hirokazu Taniguchi, Ryota Higuchi, Minoru Oshima, Keiichi Okano, Seiko Hirono, Masamichi Mizuma, Koji Arihiro, Masakazu Yamamoto, Michiaki Unno, Hiroki Yamaue, Matthew J. Weiss, Christopher L. Wolfgang, Toru Furukawa, Hitoshi Nakagama, Bert Vogelstein, Tohru Kiyono, Ralph H. Hruban, Tatsuhiro Shibata

CANCER CELL　Vol. 29　No. 2　p. 229-240　2016/02　Research paper (scientific journal)

Pancreatic cancer: molecular genomics and clinical applications

YACHIDA Shinichi, TAKAI Erina

Suizo　Vol. 31　No. 1　p. 10-16　2016

Clinical Utility of Circulating Tumor DNA for Molecular Assessment and Precision Medicine in Pancreatic Cancer

Erina Takai, Yasushi Totoki, Hiromi Nakamura, Mamoru Kato, Tatsuhiro Shibata, Shinichi Yachida

CIRCULATING NUCLEIC ACIDS IN SERUM AND PLASMA - CNAPS IX　Vol. 924　p. 13-17　2016　Research paper (scientific journal)

A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas

Olca Basturk, Seung-Mo Hong, Laura D. Wood, N. Volkan Adsay, Jorge Albores-Saavedra, Andrew V. Biankin, Lodewijk A. A. Brosens, Noriyoshi Fukushima, Michael Goggins, Ralph H. Hruban, Yo Kato, David S. Klimstra, Guenter Kloeppel, Alyssa Krasinskas, Daniel S. Longnecker, Hanno Matthaei, G. Johan A. Offerhaus, Michio Shimizu, Kyoichi Takaori, Benoit Terris, Shinichi Yachida, Irene Esposito, Toru Furukawa

AMERICAN JOURNAL OF SURGICAL PATHOLOGY　Vol. 39　No. 12　p. 1730-1741　2015/12　Research paper (scientific journal)

Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer

Erina Takai, Yasushi Totoki, Hiromi Nakamura, Chigusa Morizane, Satoshi Nara, Natsuko Hama, Masami Suzuki, Eisaku Furukawa, Mamoru Kato, Hideyuki Hayashi, Takashi Kohno, Hideki Ueno, Kazuaki Shimada, Takuji Okusaka, Hitoshi Nakagama, Tatsuhiro Shibata, Shinichi Yachida

SCIENTIFIC REPORTS　Vol. 5　2015/12　Research paper (scientific journal)

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Simeon Springer, Yuxuan Wang, Marco Dal Molin, David L. Masica, Yuchen Jiao, Isaac Kinde, Amanda Blackford, Siva P. Raman, Christopher L. Wolfgang, Tyler Tomita, Noushin Niknafs, Christopher Douville, Janine Ptak, Lisa Dobbyn, Peter J. Allen, David S. Klimstra, Mark A. Schattner, C. Max Schmidt, Michele Yip-Schneider, Oscar W. Cummings, Randall E. Brand, Herbert J. Zeh, Aatur D. Singhi, Aldo Scarpa, Roberto Salvia, Giuseppe Malleo, Giuseppe Zamboni, Massimo Falconi, Jin-Young Jang, Sun-Whe Kim, Wooil Kwon, Seung-Mo Hong, Ki-Byung Song, Song Cheol Kim, Niall Swan, Jean Murphy, Justin Geoghegan, William Brugge, Carlos Fernandez-Del Castillo, Mari Mino-Kenudson, Richard Schulick, Barish H. Edil, Volkan Adsay, Jorge Paulino, Jeanin van Hooft, Shinichi Yachida, Satoshi Nara, Nobuyoshi Hiraoka, Kenji Yamao, Susuma Hijioka, Schalk van der Merwe, Michael Goggins, Marcia Irene Canto, Nita Ahuja, Kenzo Hirose, Martin Makary, Matthew J. Weiss, John Cameron, Meredith Pittman, James R. Eshleman, Luis A. Diaz, Nickolas Papadopoulos, Kenneth W. Kinzler, Rachel Karchin, Ralph H. Hruban, Bert Vogelstein, Anne Marie Lennon

GASTROENTEROLOGY　Vol. 149　No. 6　p. 1501-1510　2015/11　Research paper (scientific journal)

期待される最新研究 わが国の家族性膵癌登録制度について

高折 恭一, 森実 千種, 谷内田 真一, 肱岡 範

膵・胆道癌Frontier　Vol. 5　No. 2　p. 98-103　2015/10

Genomic alterations in pancreatic cancer and their relevance to therapy

Erina Takai, Shinichi Yachida

WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY　Vol. 7　No. 10　p. 250-258　2015/10　Research paper (scientific journal)

膵がん研究の最近の進歩 基礎研修から臨床開発・応用へ 数理モデルによる膵臓癌テーラーメード治療戦略

山本 君代, 谷内田 真一, 中村 晶, 新井田 厚司, 大島 稔, De Subhajyoti, Iacobuzio-Donahue Christine A., 波江野 洋

日本癌学会総会記事　Vol. 74回　p. S12-6　2015/10

A case of Barrett's Esophageal Adenocarcinoma associated with heterotopic pancreas

Tatsushi Inoue, Shinichi Yachida, Hirotaka Kashiwagi, Tsuyosi Otani, Ken Ishimura, Yoshio Kushida, Keiichi Okano, Hisashi Usuki, Hisao Wakabayashi, Yasuyuki Suzuki

ESOPHAGUS　Vol. 12　No. 4　p. 392-397　2015/10　Research paper (scientific journal)

若年患者(40歳以下)に発症した膵癌の臨床・病理的特徴と生殖細胞系変異に関する検討

大本 晃弘, 森実 千種, 久保 絵美, 奥坂 拓志, 島田 和明, 谷内田 真一

膵臓　Vol. 30　No. 3　p. 358-358　2015/05

Clinicopathologic and germline mutation analysis of young patients (age 40 and younger) with pancreatic ductal adenocarcinoma.

Ohmoto, Akihiro, Morizane, Chigusa, Kubo, Emi, Takai, Erina, Shimada, Kazuaki, Okusaka, Takuji, Yachida, Shinichi

JOURNAL OF CLINICAL ONCOLOGY　Vol. 33　No. 15　2015/05

数理モデルによる膵臓癌テーラーメード治療戦略

山本 君代, 谷内田 真一, 中村 晶, 波江野 洋

膵臓　Vol. 30　No. 3　p. 356-356　2015/05

(Pro)renin receptor is crucial for Wnt/beta-catenin-dependent genesis of pancreatic ductal adenocarcinoma

Yuki Shibayama, Takayuki Fujimori, Genevieve Nguyen, Takuo Hirose, Kazuhito Totsune, Atsuhiro Ichihara, Kento Kitada, Daisuke Nakano, Hiroyuki Kobori, Masakazu Kohno, Tsutomu Masaki, Yasuyuki Suzuki, Shinichi Yachida, Akira Nishiyama

SCIENTIFIC REPORTS　Vol. 5　2015/03　Research paper (scientific journal)

Evolution and dynamics of pancreatic cancer progression

Vol. 252　No. 8　p. 851-856　2015/02/21

Revised Recommendations for Assessing Precursor Lesions in the Pancreas

Basturk Olca, Hong Seung-Mo, Wood Laura, Adsay Volkan, Albores-Saavedra Jorge, Biankin Andrew, Brosens Lodewijk, Fukushima Noriyoshi, Goggins Michael, Hruban Ralph, Kato Yo, Kern Scott, Klimstra David, Kloppel Gunter, Krasinskas Alyssa, Longnecker Daniel, Maitra Anirban, Matthei Hanno, Shimizu Michio, Takaori Kyoichi, Terris Benoit, Yachida Shinichi, Esposito Irene, Furukawa Toru

LABORATORY INVESTIGATION　Vol. 95　2015/02

Revised Recommendations for Assessing Precursor Lesions in the Pancreas

Basturk Olca, Hong Seung-Mo, Wood Laura, Adsay Volkan, Albores-Saavedra Jorge, Biankin Andrew, Brosens Lodewijk, Fukushima Noriyoshi, Goggins Michael, Hruban Ralph, Kato Yo, Kern Scott, Klimstra David, Kloppel Gunter, Krasinskas Alyssa, Longnecker Daniel, Maitra Anirban, Matthei Hanno, Offerhaus G. Johan, Shimizu Michio, Takaori Kyoichi, Terris Benoit, Yachida Shinichi, Esposito Irene, Furukawa Toru

MODERN PATHOLOGY　Vol. 28　2015/02

Heterogeneity of Pancreatic Cancer Metastases in a Single Patient Revealed by Quantitative Proteomics

Min-Sik Kim, Yi Zhong, Shinichi Yachida, N. V. Rajeshkumar, Melissa L. Abel, Arivusudar Marimuthu, Keshav Mudgal, Ralph H. Hruban, Justin S. Poling, Jeffrey W. Tyner, Anirban Maitra, Christine A. Iacobuzio-Donahue, Akhilesh Pandey

MOLECULAR & CELLULAR PROTEOMICS　Vol. 13　No. 11　p. 2803-2811　2014/11　Research paper (scientific journal)

Clinicopathology of recurrent hepatocellular carcinomas after radiofrequency ablation treated with salvage surgery

Naoki Yamamoto, Keiichi Okano, Yoshio Kushida, Akihiro Deguchi, Shinichi Yachida, Yasuyuki Suzuki

HEPATOLOGY RESEARCH　Vol. 44　No. 11　p. 1062-1071　2014/10　Research paper (scientific journal)

Factors Predicting Survival and Pathological Subtype in Patients With Ampullary Adenocarcinoma

Keiichi Okano, Minoru Oshima, Shinichi Yachida, Yoshio Kushida, Kiyohito Kato, Hideki Kamada, Masaki Wato, Tomohiko Nishihira, Yo Fukuda, Takashi Maeba, Hideyuki Inoue, Tsutomu Masaki, Yasuyuki Suzuki

JOURNAL OF SURGICAL ONCOLOGY　Vol. 110　No. 2　p. 156-162　2014/08　Research paper (scientific journal)

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

Rieko Ohki, Kozue Saito, Yu Chen, Tatsuya Kawase, Nobuyoshi Hiraoka, Raira Saigawa, Maiko Minegishi, Yukie Aita, Goichi Yanai, Hiroko Shimizu, Shinichi Yachida, Naoaki Sakata, Ryuichiro Doi, Tomoo Kosuge, Kazuaki Shimada, Benjamin Tycko, Toshihiko Tsukada, Yae Kanai, Shoichiro Sumi, Hideo Namiki, Yoichi Taya, Tatsuhiro Shibata, Hitoshi Nakagama

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 111　No. 23　p. E2404-E2413　2014/06　Research paper (scientific journal)

わが国における家族性膵癌登録制度立ち上げにむけたJohns Hopkins大学病院研修の報告

鳥嶋 雅子, 村上 裕美, 高折 恭一, 森実 千種, 谷内田 真一, 和田 慶太, 水本 雅巳, 鈴木 雅美, 細井 寛子, 小杉 眞司, 日本膵臓学会家族性膵癌レジストリ委員会

家族性腫瘍　Vol. 14　No. 2　p. A52-A52　2014/05

Clinical features of young patients (below age 40) with pancreatic ductal adenocarcinoma

Ohmoto, Akihiro, Morizane, Chigusa, Kubo, Emi, Shimada, Kazuaki, Okusaka, Takuji, Yachida, Shinichi

JOURNAL OF CLINICAL ONCOLOGY　Vol. 32　No. 3　2014/01

A novel triple secured technique for pancreatic reconstruction following pancreaticoduodenectomy for a soft pancreas.

K. Kakinoki, K. Okano, M. Oshima, H. Suto, H. Kashiwagi, N. Yamamoto, S. Akamoto, M. Fujiwara, S. Yachida, T. Takama, M. Hagiike, H. Usuki, H. Kamata, T. Masaki, Y. Suzuki

Hepato-gastroenterology　Vol. 61　p. 469-474　2014/01/01

(Pro)renin receptor is crucial for Wnt/beta-catenin-dependent genesis of pancreatic ductal adenocarcinoma

Nishiyama Akira, Hiroyuki Kobori, Hirofumi Hitomi, Daisuke Nakano, Yuki Shibayama

JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 124　p. 129P-129P　2014

Omental flap wrapping with fixation to the cut surface of the liver for reducing delayed gastric emptying after left-sided hepatectomy

Keiichi Okano, Eisuke Asano, Minoru Oshima, Naoki Yamamoto, Shinichi Yachida, Yuji Nishizawa, Shintaro Akamoto, Masao Fujiwara, Akihiro Deguchi, Hirohito Mori, Tsutomu Masaki, Yasuyuki Suzuki

SURGERY TODAY　Vol. 43　No. 12　p. 1425-1432　2013/12　Research paper (scientific journal)

Evolution and dynamics of pancreatic cancer progression

S. Yachida, C. A. Iacobuzio-Donahue

ONCOGENE　Vol. 32　No. 45　p. 5253-5260　2013/11

(Pro)renin receptorはWnt/β-catenin signalingを介して膵癌の進展に寄与する

藤森 崇行, 柴山 弓季, 谷内田 真一, 加藤 清仁, 有友 雄一, 小野 昌弘, 鎌田 英紀, 西山 成, 正木 勉

日本消化器病学会雑誌　Vol. 110　No. 臨増大会　p. A861-A861　2013/09

Immunohistochemically Detected Expression of 3 Major Genes (CDKN2A/p16, TP53, and SMAD4/DPC4) Strongly Predicts Survival in Patients With Resectable Pancreatic Cancer

Minoru Oshima, Keiichi Okano, Shinobu Muraki, Reiji Haba, Takashi Maeba, Yasuyuki Suzuki, Shinichi Yachida

ANNALS OF SURGERY　Vol. 258　No. 2　p. 336-346　2013/08　Research paper (scientific journal)

Smad6 upregulation provides an alternative mechanism for BMP inactivation in SMAD4 wild type pancreatic cancers

Jacqueline A. Brosnan, Richard Morgan, Catherine M. White, Seung-Mo Hong, Shinichi Yachida, Michael Goggins, Barish Edil, Christine A. Iacobuzio-Donahue

CANCER RESEARCH　Vol. 73　No. 8　2013/04

PS-114-2 通常型膵管癌における主要3遺伝子(p16,p53,SMAD4)の変異は生物学的悪性度を強く既定する(PS ポスターセッション,第113回日本外科学会定期学術集会)

大島 稔, 谷内田 真一, 岡野 圭一, 前場 隆志, 鈴木 康之

日本外科学会雑誌　Vol. 114　No. 2　p. 678-678　2013/03/05

PD-9-2 膵臓がんでみられるゲノムの進化(PD パネルディスカッション,第113回日本外科学会定期学術集会)

谷内田 真一

日本外科学会雑誌　Vol. 114　No. 2　p. 252-252　2013/03/05

Pancreatic thickness as a predictive factor for postoperative pancreatic fistula after distal pancreatectomy using an endopath stapler

Keiichi Okano, Minoru Oshima, Keitaro Kakinoki, Naoki Yamamoto, Shintaro Akamoto, Shinichi Yachida, Masanobu Hagiike, Hideki Kamada, Tsutomu Masaki, Yasuyuki Suzuki

SURGERY TODAY　Vol. 43　No. 2　p. 141-147　2013/02　Research paper (scientific journal)

Hepatobiliary and Pancreatic: Intrahepatic biliary cystadenocarcinoma

K. Okano, M. Oshima, N. Yamamoto, S. Yachida, Y. Suzuki

Journal of Gastroenterology and Hepatology (Australia)　Vol. 28　No. 4　2013

Extraperitoneal colostomy in laparoscopic abdominoperineal resection using a laparoscopic retractor.

Shintaro Akamoto, Seiji Noge, Jun Uemura, Norikatsu Maeda, Minoru Ohshima, Hirotaka Kashiwagi, Naoki Yamamoto, Masao Fujiwara, Shinichi Yachida, Takehiro Takama, Masanobu Hagiike, Keiichi Okano, Hisashi Usuki, Yasuyuki Suzuki

Surgery today　Vol. 43　p. 580-582　2013/01/01

Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Longterm Survivors

Shinichi Yachida, Catherine M. White, Yoshiki Naito, Yi Zhong, Jacqueline A. Brosnan, Anne M. Macgregor-Das, Richard A. Morgan, Tyler Saunders, Daniel A. Laheru, Joseph M. Herman, Ralph H. Hruban, Alison P. Klein, Sian Jones, Victor Velculescu, Christopher L. Wolfgang, Christine A. Iacobuzio-Donahue

CLINICAL CANCER RESEARCH　Vol. 18　No. 22　p. 6339-6347　2012/11　Research paper (scientific journal)

胃癌の化学放射線治療における感受性と治療後血行性転移の予測因子の検討

井上 達史, 谷内田 真一, 横平 政直, 藤原 理朗, 萩池 昌信, 高間 雄大, 岡野 圭一, 臼杵 尚志, 鈴木 康之

日本消化器外科学会雑誌　Vol. 45　No. Suppl.2　p. 252-252　2012/10

Clinicopathologic and Genetic Characterization of Traditional Serrated Adenomas of the Colon

Baojin Fu, Shinichi Yachida, Richard Morgan, Yi Zhong, Elizabeth A. Montgomery, Christine A. Iacobuzio-Donahue

AMERICAN JOURNAL OF CLINICAL PATHOLOGY　Vol. 138　No. 3　p. 356-366　2012/09　Research paper (scientific journal)

Pilot Feasibility Study of Neoadjuvant Chemoradiotherapy with S-1 in Patients with Locally Advanced Gastric Cancer Featuring Adjacent Tissue Invasion or JGCA Bulky N2 Lymph Node Metastases

Tatsushi Inoue, Shinichi Yachida, Hisashi Usuki, Tomoki Kimura, Masanobu Hagiike, Keiichi Okano, Yasuyuki Suzuki

ANNALS OF SURGICAL ONCOLOGY　Vol. 19　No. 9　p. 2937-2945　2012/09　Research paper (scientific journal)

【膵疾患診療におけるFDG-PETの有用性】TS1膵癌診断におけるFDG-PETの位置づけ Dual time point法を含めて

岡野 圭一, 大島 稔, 山本 尚樹, 谷内田 真一, 鎌田 英紀, 正木 勉, 山本 由佳, 西山 佳宏, 鈴木 康之

胆と膵　Vol. 33　No. 5　p. 397-401　2012/05

SF-030-1 膵神経内分泌癌(Panc-NEC)の臨床・病理学的ならびに分子生物学的特徴に関する検討(SF-030 サージカルフォーラム(30)膵 基礎-1(発癌,癌進展),第112回日本外科学会定期学術集会)

谷内田 真一, 岡野 圭一, 萩池 昌信, Klimstra David, Iacobuzio-Donahue Christine, 鈴木 康之

日本外科学会雑誌　Vol. 113　No. 2　p. 324-324　2012/03/05

SF-031-3 膵臓癌において免疫組織化学染色による主要遺伝子(p16,p53とSMAD4)の評価は切除後の生命予後の予知に有用である(SF-031 サージカルフォーラム(31)膵 基礎-2(病因,危険因子,発癌因子),第112回日本外科学会定期学術集会)

大島 稔, 谷内田 真一, 岡野 圭一, 萩池 昌信, 羽場 礼司, 村木 志信, 前場 隆志, 鈴木 康之

日本外科学会雑誌　Vol. 113　No. 2　p. 326-326　2012/03/05

PS-128-4 当院における胃全摘術後Pouch-Roux-Y(PRY)再建の評価(PS-128 胃 手術手技,ポスターセッション,第112回日本外科学会定期学術集会)

柏木 裕貴, 萩池 昌信, 上村 淳, 野毛 誠示, 前田 典克, 大島 稔, 山本 尚樹, 赤本 伸太郎, 藤原 理朗, 谷内田 真一, 高間 雄大, 岡野 圭一, 臼杵 尚志, 鈴木 康之

日本外科学会雑誌　Vol. 113　No. 2　p. 747-747　2012/03/05

PS-124-5 2型糖尿病合併胃癌症例に対する再建法による糖尿病改善の検討(PS-124 胃 臨床,ポスターセッション,第112回日本外科学会定期学術集会)

藤原 理朗, 上村 淳, 野毛 誠示, 前田 典克, 大島 稔, 柏木 裕貴, 山本 尚樹, 赤本 伸太郎, 谷内田 真一, 高間 雄大, 萩池 昌信, 岡野 圭一, 臼杵 尚志, 鈴木 康之

日本外科学会雑誌　Vol. 113　No. 2　p. 740-740　2012/03/05

PS-100-6 進行胆嚢癌術後の長期生存例からみた治療方針の検討(PS-100 胆 悪性-4,ポスターセッション,第112回日本外科学会定期学術集会)

岡野 圭一, 上村 淳, 野毛 誠示, 前田 典克, 大島 稔, 柏木 裕貴, 山本 尚樹, 赤本 伸太郎, 藤原 理朗, 谷内田 真一, 高間 雄大, 萩池 昌信, 臼杵 尚志, 鈴木 康之

日本外科学会雑誌　Vol. 113　No. 2　p. 692-692　2012/03/05

PS-040-1 膵頭十二指腸切除における周術期合併症対策としての早期経腸栄養の有効性に関する検討(PS-040 膵 周術期管理,第112回日本外科学会定期学術集会)

山本 尚樹, 岡野 圭一, 上村 淳, 野毛 誠司, 前田 典克, 大島 稔, 柏木 裕貴, 赤本 伸太郎, 藤原 理朗, 谷内田 真一, 高間 雄大, 萩池 昌信, 臼杵 尚志, 鈴木 康之

日本外科学会雑誌　Vol. 113　No. 2　p. 571-571　2012/03/05

PS-169-2 超高齢者緊急開腹手術症例における合併症発生因子についての検討(PS-169 高齢者・医療安全,ポスターセッション,第112回日本外科学会定期学術集会)

高間 雄大, 前田 典克, 野毛 誠示, 上村 淳, 大島 稔, 柏木 裕貴, 山本 尚樹, 赤本 伸太郎, 藤原 理朗, 谷内田 真一, 萩池 昌信, 岡野 圭一, 臼杵 尚志, 鈴木 康之

日本外科学会雑誌　Vol. 113　No. 2　p. 829-829　2012/03/05

Small Cell and Large Cell Neuroendocrine Carcinomas of the Pancreas are Genetically Similar and Distinct From Well-differentiated Pancreatic Neuroendocrine Tumors

Shinichi Yachida, Efsevia Vakiani, Catherine M. White, Yi Zhong, Tyler Saunders, Richard Morgan, Roeland F. de Wilde, Anirban Maitra, Jessica Hicks, Angelo M. DeMarzo, Chanjuan Shi, Rajni Sharma, Daniel Laheru, Barish H. Edil, Christopher L. Wolfgang, Richard D. Schulick, Ralph H. Hruban, Laura H. Tang, David S. Klimstra, Christine A. Iacobuzio-Donahue

AMERICAN JOURNAL OF SURGICAL PATHOLOGY　Vol. 36　No. 2　p. 173-184　2012/02　Research paper (scientific journal)

Novel therapeutic approaches in pancreatic cancer based on genomic alterations

Shinichi Yachida

Current Pharmaceutical Design　Vol. 18　No. 17　p. 2452-2463　2012　Research paper (scientific journal)

Sessile serrated adenomas and classical adenomas: an epigenetic perspective on premalignant neoplastic lesions of the gastrointestinal tract

Mashaal Dhir, Shinichi Yachida, Leander Van Neste, Sabine C. Gloeckner, Jana Jeschke, Emmanouil P. Pappou, Elizabeth A. Montgomery, James G. Herman, Stephen B. Baylin, Christine Iacobuzio-Donahue, Nita Ahuja

INTERNATIONAL JOURNAL OF CANCER　Vol. 129　No. 8　p. 1889-1898　2011/10　Research paper (scientific journal)

A case of splenic pseudoaneurysm of chronic pancreatitis treated with Frey's operation after transcatheter splenic arterial embolization

SUTO Hironobu, OKANO Keiichi, KAKINOKI Keitaro, MAEDA Norikatsu, OSHIMA Minoru, KASHIWAGI Hirotaka, YAMAMOTO Naoki, AKAMOTO Shintaro, FUJIWARA Masao, YACHIDA Shinichi, TAKAMA Takehiro, HAGIIKE Masanobu, USUKI Hisashi, SUZUKI Yasuyuki

Vol. 26　No. 4　p. 544-548　2011/08/25

Establishment and Characterization of a New Cell Line, A99, From a Primary Small Cell Carcinoma of the Pancreas

Shinichi Yachida, Yi Zhong, Raul Patrascu, Meghan B. Davis, Laura A. Morsberger, Constance A. Griffin, Ralph H. Hruban, Daniel Laheru, Christine A. Iacobuzio-Donahue

PANCREAS　Vol. 40　No. 6　p. 905-910　2011/08　Research paper (scientific journal)

GATA6 Activates Wnt Signaling in Pancreatic Cancer by Negatively Regulating the Wnt Antagonist Dickkopf-1

Yi Zhong, Zheng Wang, Baojin Fu, Fan Pan, Shinichi Yachida, Mousumi Dhara, Emilia Albesiano, Li Li, Yoshiki Naito, Felip Vilardell, Christopher Cummings, Paola Martinelli, Ang Li, Raluca Yonescu, Qingyong Ma, Constance A. Griffin, Francisco X. Real, Christine A. Iacobuzio-Donahue

PLOS ONE　Vol. 6　No. 7　2011/07　Research paper (scientific journal)

BAMBI Is overexpressed in metastatic pancreatic cancers with genetically Intact TGF-beta pathways: A potential mechanism to escape TGF-beta signaling during metastasis formation

Jacqueline A. Brosnan, Shinichi Yachida, Christine A. Iacobuzio-Donahue

CANCER RESEARCH　Vol. 71　2011/04

Clinicopathologic and Genetic Characterization of Traditional Serrated Polyps of the Colon

B. Fu, S. Yachida, R. Morgan, Y. Zhong, E. A. Montgomery, C. A. Iacobuzio-Donahue

LABORATORY INVESTIGATION　Vol. 91　p. 148A-148A　2011/02

Clinicopathologic and Genetic Characterization of Traditional Serrated Polyps of the Colon

B. Fu, S. Yachida, R. Morgan, Y. Zhong, E. A. Montgomery, C. A. Iacobuzio-Donahue

MODERN PATHOLOGY　Vol. 24　p. 148A-148A　2011/02

Jun Activation Domain Binding Protein 1 is Overexpressed from the Very Early Stages of Hepatocarcinogenesis

Shinichi Yachida, Katsumi Imaida, Masanao Yokohira, Nozomi Hashimoto, Shugo Suzuki, Keiichi Okano, Hisao Wakabayashi, Hajime Maeta, Yasuyuki Suzuki

ANNALS OF SURGICAL ONCOLOGY　Vol. 17　No. 12　p. 3386-3393　2010/12　Research paper (scientific journal)

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

Peter J. Campbell, Shinichi Yachida, Laura J. Mudie, Philip J. Stephens, Erin D. Pleasance, Lucy A. Stebbings, Laura A. Morsberger, Calli Latimer, Stuart McLaren, Meng-Lay Lin, David J. McBride, Ignacio Varela, Serena A. Nik-Zainal, Catherine Leroy, Mingming Jia, Andrew Menzies, Adam P. Butler, Jon W. Teague, Constance A. Griffin, John Burton, Harold Swerdlow, Michael A. Quail, Michael R. Stratton, Christine Iacobuzio-Donahue, P. Andrew Futreal

NATURE　Vol. 467　No. 7319　p. 1109-1113　2010/10　Research paper (scientific journal)

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Shinichi Yachida, Sian Jones, Ivana Bozic, Tibor Antal, Rebecca Leary, Baojin Fu, Mihoko Kamiyama, Ralph H. Hruban, James R. Eshleman, Martin A. Nowak, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Christine A. Iacobuzio-Donahue

NATURE　Vol. 467　No. 7319　p. 1114-U126　2010/10　Research paper (scientific journal)

Successful Treatment of a Primary Gastric T-cell Lymphoma Lacking the Human T-cell Leukemia Virus Type 1

Shinichi Yachida, Mitsuru Sasako, Kensei Tobinai, Yoshihiro Matsuno, Tadakazu Shimoda

HEPATO-GASTROENTEROLOGY　Vol. 57　No. 98　p. 383-387　2010/03　Research paper (scientific journal)

Pancreatic Schwannoma in a 32-Year-Old Woman Mimicking a Solid-Pseudopapillary Neoplasm

Minoru Oshima, Shinichi Yachida, Yasuyuki Suzuki

Clinical Gastroenterology and Hepatology　Vol. 8　No. 1　p. e1-e2　2010/01　Research paper (scientific journal)

Beta-catenin Nuclear Labeling is a Common Feature of Sessile Serrated Adenomas and Correlates With Early Neoplastic Progression After BRAF Activation

Shinichi Yachida, Shiyama Mudali, Sherri A. Martin, Elizabeth A. Montgomery, Christine A. Iacobuzio-Donahue

AMERICAN JOURNAL OF SURGICAL PATHOLOGY　Vol. 33　No. 12　p. 1823-1832　2009/12　Research paper (scientific journal)

Prediction of posthepatectomy hepatic functional reserve by serum hyaluronate

S. Yachida, H. Wakabayashi, K. Okano, Y. Suzuki

BRITISH JOURNAL OF SURGERY　Vol. 96　No. 5　p. 501-508　2009/05　Research paper (scientific journal)

DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer

Christine A. Iacobuzio-Donahue, Baojin Fu, Shinichi Yachida, Mingde Luo, Hisashi Abe, Clark M. Henderson, Felip Vilardell, Zheng Wang, Jesse W. Keller, Priya Banerjee, Joseph M. Herman, John L. Cameron, Charles J. Yeo, Marc K. Halushka, James R. Eshleman, Marian Raben, Alison P. Klein, Ralph H. Hruban, Manuel Hidalgo, Daniel Laheru

JOURNAL OF CLINICAL ONCOLOGY　Vol. 27　No. 11　p. 1806-1813　2009/04　Research paper (scientific journal)

The Pathology and Genetics of Metastatic Pancreatic Cancer

Shinichi Yachida, Christine A. Iacobuzio-Donahue

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE　Vol. 133　No. 3　p. 413-422　2009/03

Minute Gallbladder Carcinoma Associated With an Anastomotic Cholecystoduodenal Fistula

Shinichi Yachida, Kunihiko Tsutsui, Yasuyuki Suzuki

Clinical Gastroenterology and Hepatology　Vol. 7　No. 2　p. e6-e7　2009/02　Research paper (scientific journal)

Immunohistochemically Detected Expression of p27(Kip1) and Skp2 Predicts Survival in Patients with Intrahepatic Cholangiocarcinomas

Nozomi Hashimoto, Shinichi Yachida, Keiichi Okano, Hisao Wakabayashi, Katsumi Imaida, Kazutaka Kurokohchi, Tsutomu Masaki, Hisoka Kinoshita, Masahiro Tominaga, Tetsuo Ajiki, Yonson Ku, Takehiro Okabayashi, Kazuhiro Hanazaki, Makoto Hiroi, Sadanobu Izumi, Shohei Mano, Setsuo Okada, Yukihiko Karasawa, Takashi Maeba, Yasuyuki Suzuki

ANNALS OF SURGICAL ONCOLOGY　Vol. 16　No. 2　p. 395-403　2009/02　Research paper (scientific journal)

Scirrhous Hepatocellular Carcinoma: Unique Computed Tomography Findings

Shinichi Yachida, Hisao Wakabayashi, Yasuyuki Suzuki

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY　Vol. 7　No. 1　p. XXVIII-XXVIII　2009/01

Genetic and Epigenetic Alterations of Familial Pancreatic Cancers

Kieran Brune, Seung-Mo Hong, Ang Li, Shinichi Yachida, Tadayoshi Abe, Margaret Griffith, Dawei Yang, Noriyuki Omura, James Eshleman, Marcia Canto, Rich Schulick, Alison P. Klein, Ralph H. Hruban, Christine Iacobuzio-Donohue, Michael Goggins

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION　Vol. 17　No. 12　p. 3536-3542　2008/12　Research paper (scientific journal)

AUTOANTIBODIOMICS APPROACH IDENTIFYING NOVEL ANTIBODIES IN PATIENTS WITH PANCREATIC CANCER

K. Takaori, T. Nakanishi, C. A. Iacobuzio-Donahue, S. Yachida, A. Klein, R. H. Hruban, Y. Miyamoto, N. Tanigawa, Y. Tabushi, T. Takubo

PANCREAS　Vol. 37　No. 4　p. 497-498　2008/11

p27(Kip1) is overexpressed in very early stages of hepatocarcinogenesis

Shinichi Yachida, Michiie Sakamoto, Katsumi Imaida, Masanao Yokohira, Kousuke Saoo, Keiichi Okano, Hisao Wakabayashi, Hajime Maeta, Yasuyuki Suzuki

CANCER SCIENCE　Vol. 99　No. 11　p. 2152-2159　2008/11　Research paper (scientific journal)

A simple and safe pancreas transection using a stapling device for a distal pancreatectomy

Keiichi Okano, Keitarou Kakinoki, Shinichi Yachida, Kunihiko Izuishi, Hisao Wakabayashi, Yasuyuki Suzuki

JOURNAL OF HEPATO-BILIARY-PANCREATIC SURGERY　Vol. 15　No. 4　p. 353-358　2008/07　Research paper (scientific journal)

Ossifying intramuscular metastases from colon cancer

Takaaki Yano, Hisao Wakabayashi, Shinichi Yachida, Keiichi Okano, Kunihiko Izuishi, Yasuyuki Suzuki

ANZ JOURNAL OF SURGERY　Vol. 78　No. 6　2008/06

A stercoral perforation of the colon with an obvious faecal mass diagnosed by computed tomography

Takaaki Yano, Hisao Wakabayashi, Shinichi Yachida, Keiichi Okano, Kunihiko Izuishi, Yasuyuki Suzuki

ANZ JOURNAL OF SURGERY　Vol. 78　No. 3　p. 214-U7　2008/03

Role of 18F-fluorodeoxyglucose positron emission tomography imaging in surgery for pancreatic cancer

Hisao Wakabayashi, Yoshihiro Nishiyama, Tsuyoshi Otani, Takanori Sano, Shinichi Yachida, Keiichi Okano, Kunihiko Izuishi, Yasuyuki Suzuki

WORLD JOURNAL OF GASTROENTEROLOGY　Vol. 14　No. 1　p. 64-69　2008/01　Research paper (scientific journal)

Validation of risk assessment scoring systems for an audit of elective surgery for gastrointestinal cancer in elderly patients: An audit

Hisao Wakabayashi, Takanori Sano, Shinichi Yachida, Keiichi Okano, Kunihiko Izuishi, Yasuyuki Suzuki

International Journal of Surgery　Vol. 5　No. 5　p. 323-327　2007/10　Research paper (scientific journal)

Obstructive jaundice caused by bile duct involvement in intra-abdominal non-Hodgkin lymphoma: An unusual initial manifestation

H. Wakabayashi, S. Yachida, Y. Suzuki

DIGESTIVE AND LIVER DISEASE　Vol. 39　No. 7　p. 692-692　2007/07

Neutrophil elastase inhibitor (Sivelestat) preserves antitumor immunity and reduces the inflammatory mediators associated with major surgery

Shintaro Akamoto, Keiichi Okano, Takanori Sano, Shinichi Yachida, Kunihiko Izuishi, Hisashi Usuki, Hisao Wakabayashi, Yasuyuki Suzuki

SURGERY TODAY　Vol. 37　No. 5　p. 359-365　2007/05　Research paper (scientific journal)

DP-147-3 胆管細胞癌におけるp27とその関連細胞周期シグナルに関する免疫組織化学的検討(第107回日本外科学会定期学術集会)

橋本 希, 谷内田 真一, 岡野 圭一, 若林 久男, 今井田 克己, 鈴木 康之

日本外科学会雑誌　Vol. 108　No. 2　p. 613-613　2007/03/10

Central venous catheter-related infection diagnosed by CT

Hisao Wakabayashi, Tsuyoshi Otani, Shinichi Yachida, Keiichi Okano, Kunihiko Izuishi, Yasuyuki Suzuki

LANCET　Vol. 368　No. 9545　p. 1466-1466　2006/10

ラット中期多臓器発がん性試験法を用いたアカネ色素の発がん修飾作用

横平 政直, 山川 けいこ, 細川 京子, 松田 陽子, 谷内田 真一, 竿尾 光祐, 久野 壽也, 今井田 克己

日本癌学会総会記事　Vol. 65回　p. 108-108　2006/09

肝多段階発癌過程におけるp27とその関連細胞周期シグナル(Jab1とSkp2)の遺伝子発現とその臨床的意義

谷内田 真一, 岡野 圭一, 若林 久男, 横平 政直, 竿尾 光祐, 今井田 克己

日本癌学会総会記事　Vol. 65回　p. 174-174　2006/09

F-18-FDG accumulations in primary malignant melanoma of the esophagus

Keiichi Okano, Toru Sugiyama, Shintaro Akamoto, Shinichi Yachida, Hisashi Usuki, Hisao Wakabayashi, Hajime Maeta

SURGERY　Vol. 140　No. 1　p. 118-119　2006/07

Improved microcirculatory effect of D-allose on hepatic ischemia reperfusion following partial hepatectomy in cirrhotic rat liver

MA Hossain, H Wakabayashi, K Izuishi, K Okano, S Yachida, M Tokuda, K Izumori, H Maeta

JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 101　No. 4　p. 369-371　2006/04　Research paper (scientific journal)

肝細胞癌の多段階発癌過程におけるp27とその関連細胞周期シグナルの発現に関する検討

谷内田 真一, 若林 久男, 岡野 圭一, 赤本 伸太郎, 臼杵 尚志, 横平 政直, 今井田 克己, 前田 肇

日本外科学会雑誌　Vol. 107　No. 2　p. 375-375　2006/03/05

Dissection of para-aortic lymph node metastasis after surgery for hepatocellular carcinoma - Report of a case

Shintaro Akamoto, Kunihiko Izuishi, Shinichi Yachida, Keiichi Okano, Fuminori Goda, Hisao Wakabayashi, Hisashi Usuki, Hajime Maeta

Japanese Journal of Gastroenterological Surgery　Vol. 39　No. 3　p. 312-316　2006　Research paper (scientific journal)

Report of 5 surgically treated for malignant tumors with nephrotic syndrome

Takaaki Yano, Hisao Wakabayashi, Shintaro Akamoto, Shinichi Yachida, Keiichi Okano, Hisashi Usuki, Hajime Maeta

Japanese Journal of Gastroenterological Surgery　Vol. 39　No. 10　p. 1627-1631　2006　Research paper (scientific journal)

The role of prostaglandins in liver ischemia-reperfusion injury

M. A. Hossain, H. Wakabayashi, K. Izuishi, K. Okano, S. Yachida, H. Maeta

CURRENT PHARMACEUTICAL DESIGN　Vol. 12　No. 23　p. 2935-2951　2006

Significance of fluorodeoxyglucose PET imaging in the diagnosis of malignancies in patients with biliary stricture

H Wakabayashi, S Akamoto, S Yachida, K Okano, K Izuishi, Y Nishiyama, H Maeta

EJSO　Vol. 31　No. 10　p. 1175-1179　2005/12　Research paper (scientific journal)

肝多段階発癌過程におけるp27とその関連細胞周期シグナルの発現に関する免疫組織化学的検討

谷内田 真一, 坂元 享宇, 小出 紀正, 臼杵 尚志, 岡野 圭一, 横平 政直, 竿尾 光祐, 今井田 克己

日本癌学会総会記事　Vol. 64回　p. 233-233　2005/09

肝細胞癌多段階発癌におけるp27とその関連細胞周期シグナルに関する免疫組織化学的検討(肝・胆・膵20, 第60回日本消化器外科学会総会)

谷内田 真一, 岡野 圭一, 若林 久男, 横平 政直, 今井田 克己, 坂元 享宇, 前田 肇

日本消化器外科学会雑誌　Vol. 38　No. 7　p. 1185-1185　2005/07/01

Adequate selection of fluoropyrimidines for colorectal cancer

H Usuki, S Akamoto, T Sugiyama, M Yamane, S Yachida, K Okano, K Izuishi, H Wakabayashi, H Maeta

Proceedings of the 10th Congress of Asian Federation of Coloproctology: Controversies in Colorectal Surgery　p. 81-86　2005　Research paper (international conference proceedings)

The usefulness of the sensitivity test which considers the metabolism of anti-cancer drugs for gastric cancer

H Usuki, S Akamoto, T Sugiyama, S Yachida, K Okano, K Lzuishi, H Wakabayashi, H Maeta

Proceedings of the 6th International Gastric Cancer Congress　p. 259-264　2005　Research paper (international conference proceedings)

TS-1 therapy via intestinal catheter used for tube feeding in a patient with gastric cancer after total gastrectomy

Masanobu Hagiike, Yuka Tsuboi, Shintaro Akamoto, Shinichi Yachida, Kunihiko Izuishi, Yukihiko Karasawa, Fuminori Goda, Setsuo Okada, Hisashi Usuki, Hajime Maeta

Gan to kagaku ryoho. Cancer & chemotherapy　Vol. 32　p. 1033-1036　2005/01/01

Metastatic carcinoma of the tongue at a percutaneous endoscopic gastrostomy site

Fuminori Goda, Yukihiko Karasawa, Shinichi Yachida, Masanobu Hagiike, Kunihiko Izuishi, Setsuo Okada, Hisashi Usuki, Hajime Maeta, Shoichi Senda

Gastroenterological Endoscopy　Vol. 46　p. 2107-2112　2004/09/01

Double-J stent drainage by endoscopy for infectious pancreatic pseudocyst after laparoscopic gastrocystostomy: A case report

M Hagiike, T Yano, F Goda, S Yachida, K Izuishi, S Okada, H Usuki, H Maeta

PROCEEDINGS OF THE 9TH WORLD CONGRESS OF ENDOSCOPIC SURGERY　p. 137-141　2004　Research paper (international conference proceedings)

Adenosquamous carcinoma of the esophagus - Clinicopathologic study of 18 cases

S Yachida, Y Nakanishi, T Shimoda, S Nimura, H Igaki, Y Tachimori, H Kato

ONCOLOGY　Vol. 66　No. 3　p. 218-225　2004　Research paper (scientific journal)

Alpha-fetoprotein-producing carcinoma of the colon - Report of a case and review of the literature

S Yachida, N Fukushima, Y Nakanishi, T Akasu, H Kitamura, M Sakamoto, T Shimoda

DISEASES OF THE COLON & RECTUM　Vol. 46　No. 6　p. 826-831　2003/06　Research paper (scientific journal)

Dihydropyrimidine dehydrogenase (DPD) activity in gastric cancer tissue and effect of DPD inhibitory fluoropyrimidines

Hisashi Usuki, Ken Ishimura, Shinichi Yachida, Masanobu Hagiike, Keiichi Okano, Kunihiko Izuishi, Yukihiko Karasawa, Fuminori Goda, Hajime Maeta

Gastric Cancer　Vol. 6　No. 1　p. 66-70　2003　Research paper (international conference proceedings)

Clear cell endocrine tumor of the pancreas which is not associated with von Hippel-Lindau disease: Report of a case

S Nunobe, N Fukushima, S Yachida, K Shimada, T Kosuge, M Sakamoto

SURGERY TODAY　Vol. 33　No. 6　p. 470-474　2003　Research paper (scientific journal)

Pancreatic metastasis from renal cell carcinoma extending into the main pancreatic duct: a case report

S Yachida, N Fukushima, Y Kanai, S Nimura, K Shimada, J Yamamoto, M Sakamoto

JAPANESE JOURNAL OF CLINICAL ONCOLOGY　Vol. 32　No. 8　p. 315-317　2002/08　Research paper (scientific journal)

Evaluation of liver function for the application of preoperative portal vein embolization on major hepatic resection

H Wakabayashi, S Yachida, T Maeba, H Maeta

HEPATO-GASTROENTEROLOGY　Vol. 49　No. 46　p. 1048-1052　2002/07　Research paper (scientific journal)

Implications of peritoneal washing cytology in patients with potentially resectable pancreatic cancer

S Yachida, N Fukushima, M Sakamoto, Y Matsuno, T Kosuge, S Hirohashi

BRITISH JOURNAL OF SURGERY　Vol. 89　No. 5　p. 573-578　2002/05　Research paper (scientific journal)

Less aggressive features of colorectal cancer with liver metastases showing macroscopic intrabiliary extension

Makoto Kubo, Michiie Sakamoto, Noriyoshi Fukushima, Shinichi Yachida, Yukihiro Nakanishi, Tadakazu Shimoda, Junji Yamamoto, Yoshihiro Moriya, Setsuo Hirohashi

Pathology International　Vol. 52　No. 8　p. 514-518　2002　Research paper (scientific journal)

Minute pancreatic adenocarcinoma presenting with stenosis of the main pancreatic duct

Shinichi Yachida, Noriyoshi Fukushima, Kazuaki Nakanishi, Kazuaki Shimada, Tomoo Kosuge, Michiie Sakamoto

Pathology International　Vol. 52　No. 9　p. 607-611　2002　Research paper (scientific journal)

Phosphoglyceride crystal deposition disease presenting as multiple paragastric masses

Shinichi Yachida, Noriyoshi Fukushima, Yukihiro Nakanishi, Satoshi Nimura, Masahiko Sato, Kazuaki Shimada, Katsutoshi Miura, Michiie Sakamoto

Digestive Diseases and Sciences　Vol. 47　No. 6　p. 1413-1418　2002　Research paper (scientific journal)

Long-term survival after resection for small cell carcinoma of the esophagus

S Yachida, K Matsushita, H Usuki, H Wanibuchi, T Maeba, H Maeta

ANNALS OF THORACIC SURGERY　Vol. 72　No. 2　p. 596-597　2001/08　Research paper (scientific journal)

Endoscopically demonstrable esophageal changes after Helicobacter pylori eradication in patients with gastric disease

Shinichi Yachida, Daizo Saito, Takahiro Kozu, Takuji Gotoda, Tetsuya Inui, Mitsuhiro Fujishiro, Ichiro Oda, Takehiro Okabayashi, Yasuo Kakugawa, Hiroyuki Ono, Hitoshi Kondo

Journal of Gastroenterology and Hepatology (Australia)　Vol. 16　No. 12　p. 1346-1352　2001　Research paper (scientific journal)

Usefulness of indigo carmine chromoendoscopy and endoscopic clipping for accurate preoperative assessment of proximal gastric cancer

T Okabayashi, T Gotoda, H Kondo, H Ono, Oda, I, M Fujishiro, S Yachida

ENDOSCOPY　Vol. 32　No. 10　p. S62-S62　2000/10　Research paper (scientific journal)

Preventive effect of preoperative portal vein ligation on endotoxin-induced hepatic failure in hepatectomized rats is associated with reduced tumour necrosis factor alpha production

S Yachida, K Ikeda, K Kaneda, F Goda, T Maeba, H Maeta

BRITISH JOURNAL OF SURGERY　Vol. 87　No. 10　p. 1382-1390　2000/10　Research paper (scientific journal)

Measurement of serum hyaluronate as a predictor of human liver failure after major hepatectomy

S Yachida, H Wakabayashi, Y Kokudo, F Goda, S Okada, T Maeba, H Maeta

WORLD JOURNAL OF SURGERY　Vol. 24　No. 3　p. 359-364　2000/03　Research paper (scientific journal)

A CASE OF QUADRUPLE EARLY CANCER ARISING FROM THE RENAL PELVIS, STOMACH, RECTUM AND LUNG

YACHIDA Shinichi, USUKI Hisashi, SEKIMATA Takeo, MORI Seiji, MAEBA Takashi, MAETA Hajime

The journal of the Japanese Practical Surgeon Society　Vol. 61　No. 5　p. 1355-1358　2000

Indications for portal vein embolization combined with major hepatic resection for advanced-stage hepatocellular carcinomas - A preliminary clinical study

H Wakabayashi, S Yachida, T Maeba, H Maeta

DIGESTIVE SURGERY　Vol. 17　No. 6　p. 587-594　2000　Research paper (scientific journal)

原発性虫垂癌の5例

唐澤 幸彦, 前場 隆志, 前田 肇, 坪井 有加, 横平 政直, 谷内田 真一, 三沢 篤志, 岡野 圭一, 森 誠治, 合田 文則

香川県医師会誌　Vol. 52　No. 特別　p. 48-48　1999/08

The preventive effect of preopearative portal vein branch ligation against endotoxin-induced liver failure after partial hepatectomy in rats

S Yachida, K Ikeda, K Kaneda, F Goda, T Maeba, H Maeta

CELLS OF THE HEPATIC SINUSOID, VOL 7　p. 245-246　1999　Research paper (international conference proceedings)

THERMOGRAM AND NITRIC OXIDE OF BREAST TUMOR

USUKI Hisashi, GODA Fuminori, YACHIDA Shinichi, MOROGUCHI Akito, KONDO Akihiro, ISHIMURA Ken, MORI Seiji, OKADA Setsuo, WAKABAYASHI Hisao, MAEBA Takashi, MAETA Hajime

Vol. 18　No. 1　p. 64-66　1998/06/10

Evaluation of clinical factors affecting the hypertrophy of the non- embolized lobe after the preoperative portal vein embolization (PTPE) in patients who underwent major hepatic resection with PTPE

Hisao Wakabayashi, Shinichi Yachida, Takashi Maeba, Hisashi Usuki, Setsuo Okada, Fuminori Goda, Seiji Mori, Hajime Maeta

Acta Hepatologica Japonica　Vol. 39　No. 7　p. 454-460　1998/01/01

Morphological and functional alterations to sinusoidal endothelial cells in the early phase of endotoxin-induced liver failure after partial hepatectomy in rats

Shinichi Yachida, Yasutaka Kokudo, Hisao Wakabayashi, Takashi Maeba, Kenji Kaneda, Hajime Maeta

Virchows Archiv　Vol. 433　No. 2　p. 173-181　1998　Research paper (scientific journal)

Early detection of sinusoidal endothelial cell damage by serum hyaluronate levels after partial hepatectomy in rats.

S Yachida, Y Kokudo, H Wakabayashi, K Okano, Y Karasawa, S Mori, F Goda, Y Hirata, T Maeba, K Kaneda, H Maeta

GASTROENTEROLOGY　Vol. 112　No. 4　p. A1418-A1418　1997/04

Effect of preoperative portal vein embolization on major hepatectomy in damaged liver

H Wakabayashi, S Yachida, S Okada, T Maeba, H Maeta

GASTROENTEROLOGY　Vol. 112　No. 4　p. A1410-A1410　1997/04

A case of an inflammatory polyp in common bile duct treated by endoscopic polypectomy

Ken Ishimura, Akihiro Kondo, Shinichi Yachida, Haruhiro Yonemoto, Keiichi Okano, Yasutaka Kokudo, Hisao Wakabayashi, Takashi Maeba

Gastroenterological Endoscopy　Vol. 38　p. 917-923　1996/12/01

Clinical significances of serum hyaluronic acid levels in evaluating liver preserving function before partial hepatectomy

Shinichi Yachida, Hisao Wakabayashi, Takashi Maeba, Hajime Maeta

Acta Hepatologica Japonica　Vol. 37　p. 231-232　1996/12/01

Protective effects of antithrombin III supplementation on warm ischemia and reperfusion injury in rat liver

K Okano, Y Kokudo, K Okajima, MA Hossain, K Ishimura, S Yachida, T Tsubouchi, H Wakabayashi, T Maeba, H Maeta

WORLD JOURNAL OF SURGERY　Vol. 20　No. 8　p. 1069-1075　1996/10　Research paper (scientific journal)

Clinical significances of serum hyaluronate levels in evaluating liver preserving function before partial hepatectomy

S Yachida, H Wakabayashi, T Maeba, H Maeta

GASTROENTEROLOGY　Vol. 110　No. 4　p. A1363-A1363　1996/04

Role of preoperative portal vein embolization for advanced hepatocellular carcinoma in injured liver.

H Wakabayashi, S Yachida, K Okano, H Usuki, T Maeba, H Maeta

GASTROENTEROLOGY　Vol. 110　No. 4　p. A1356-A1356　1996/04

Curative resection for malignant glucagonoma

Ken Ishimura, Shinichi Yachida, Keiichi Okano, Yasutaka Kokudo, Setsuo Okada, Hisao Wakabayashi, Takashi Maeba, Hajime Maeta

Journal of Hepato-Biliary-Pancreatic Surgery　Vol. 3　No. 4　p. 498-501　1996　Research paper (scientific journal)

Effect of luminal flush on mucosal injury during cold ischemia in the rat small bowel

Y. Kokudo, M. Itoh, S. Mori, Y. Karasaw, K. Okano, S. Yachida, K. Ishimura, H. Wakabayashi, T. Maeba, H. Maeta

Transplantation Proceedings　Vol. 28　No. 3　p. 1841-1842　1996　Research paper (international conference proceedings)