「検査側を上にした側臥位」が有用であったが,生検診断ができなかった1例

樋口 貴俊, 町山 裕知, 為定 裕貴, 岡部 福子, 橋本 和樹, 高田 創, 内藤 真依子, 益弘 健太朗, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 武田 吉人, 熊ノ郷 淳

気管支学　Vol. 46　No. 2　p. 131-131　2024/03

細胞外小胞のプロテオミクスによる肺非結核性抗酸菌症と肺結核の鑑別を可能とする新規バイオマーカー探索

内藤 真依子, 武田 吉人, 枝廣 龍哉, 白井 雄也, 森 雅秀, 矢野 幸洋, 高田 創, 益弘 健太朗, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 166-166　2024/03

非小細胞肺癌 複合免疫療法 実地臨床におけるニボルマブ+イピリムマブ+化学療法vsペンブロリズマブ+化学療法の有効性・安全性を評価した傾向スコアマッチング比較研究

松本 錦之介, 白山 敬之, 田宮 基裕, 南 俊行, 甲原 雄平, 田宮 朗裕, 菅 泰彦, 久下 朋輝, 森 雅秀, 鈴木 秀和, 飛田 哲志, 灘波 良信, 鉄本 訓史, 二木 俊江, 森村 治, 長 彰翁, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 182-182　2024/03

腫瘍TR 血清エクソソームと腫瘍組織の統合プロテオミクスによるSCLCの新規BM及び治療標的としてのSUCLA2の同定

山本 真, 菅 泰彦, 武田 吉人, 谷崎 智史, 榎本 貴俊, 吉村 華子, 網屋 沙織, 原 伶奈, 川崎 貴裕, 白山 敬之, 三宅 浩太郎, 伊藤 眞里, 足立 淳, 上條 陽平, 澤田 隆介, 山西 芳裕, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 212-212　2024/03

TSC-LAMにおける呼吸機能の経時的変化

樋口 貴俊, 平田 陽彦, 高田 創, 内藤 真依子, 益弘 健太朗, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 319-319　2024/03

肺移植を検討した造血幹細胞移植後閉塞性細気管支炎症候群の予後 後方視的研究

橋本 和樹, 平田 陽彦, 高田 創, 内藤 真依子, 益弘 健太朗, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 344-344　2024/03

Progressive pulmonary fibrosisにおける抗線維化薬の効果の探索

新津 敬之, 福島 清春, 白山 敬之, 木田 博, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 315-315　2024/03

Cancer-associated SNRPD3 mutation confers resistance to hypoxia, which is attenuated by DRP1 inhibition.

Shingo Satoh, Kotaro Miyake, Yuichi Adachi, Kentaro Masuhiro, Shinji Futami, Yujiro Naito, Takayuki Shiroyama, Shohei Koyama, Yuta Yamaguchi, Hachiro Konaka, Hyota Takamatsu, Daisuke Okuzaki, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Biochemical and biophysical research communications　Vol. 696　p. 149511-149511　2024/01/10　Research paper (scientific journal)

Real-world outcomes of nivolumab plus ipilimumab and pembrolizumab with platinum-based chemotherapy in advanced non-small cell lung cancer: a multicenter retrospective comparative study.

Kinnosuke Matsumoto, Takayuki Shiroyama, Motohiro Tamiya, Toshiyuki Minami, Yuhei Kinehara, Akihiro Tamiya, Yasuhiko Suga, Tomoki Kuge, Masahide Mori, Hidekazu Suzuki, Satoshi Tobita, Kiyonobu Ueno, Yoshinobu Namba, Satoshi Tetsumoto, Toshie Niki, Osamu Morimura, Akio Osa, Kazumi Nishino, Izumi Nagatomo, Yoshito Takeda, Takashi Kijima, Atsushi Kumanogoh

Cancer immunology, immunotherapy : CII　Vol. 73　No. 1　p. 4-4　2024/01/04　Research paper (scientific journal)

Balloon Dilatation for Bronchoscope Delivery in a Swine Model: A Novel Technique for Ultra-Peripheral Lung Field Access and Accurate Biopsy.

Kotaro Miyake, Takayuki Shiroyama, Shingo Satoh, Yuichi Adachi, Kika Ohira, Yuko Abe, So Takata, Kentaro Masuhiro, Yujiro Naito, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Respiration; international review of thoracic diseases　Vol. 103　No. 4　p. 205-213　2024　Research paper (scientific journal)

免疫チェックポイント阻害薬使用後の経過で,麻痺性イレウスを発症した1例

大平 貴華, 白山 敬之, 谷崎 智史, 東 浩志, 山本 有美子, 細野 裕貴, 内藤 真依子, 平田 陽彦, 武田 吉人, 熊ノ郷 淳

肺癌　Vol. 63　No. 6　p. 904-904　2023/10

EGFR遺伝子変異陽性肺癌患者におけるミノサイクリン内服の予後への影響

刀祢 麻里, 岩堀 幸太, 白井 雄也, 高田 創, 益弘 健太朗, 内藤 真依子, 内藤 祐二朗, 福島 清春, 白山 敬之, 三宅 浩太郎, 小山 正平, 平田 陽彦, 長友 泉, 武田 吉人, 和田 尚, 熊ノ郷 淳

肺癌　Vol. 63　No. 5　p. 600-600　2023/10

EGFR遺伝子変異陽性肺癌患者におけるミノサイクリン内服の予後への影響

刀祢 麻里, 岩堀 幸太, 白井 雄也, 高田 創, 益弘 健太朗, 内藤 真依子, 内藤 祐二朗, 福島 清春, 白山 敬之, 三宅 浩太郎, 小山 正平, 平田 陽彦, 長友 泉, 武田 吉人, 和田 尚, 熊ノ郷 淳

肺癌　Vol. 63　No. 5　p. 600-600　2023/10

血清エクソソームの最新プロテオミクスによる小細胞肺癌の新規バイオマーカーの探索(Proteomics of serum extracellular vesicles identifies a novel SCLC biomarker)

山本 真, 菅 泰彦, 武田 吉人, 中坪 大亮, 谷崎 智史, 榎本 貴俊, 吉村 華子, 原 伶奈, 川崎 貴裕, 白山 敬之, 三宅 浩太郎, 足立 淳, 上條 陽平, 澤田 隆介, 山西 芳裕, 熊ノ郷 淳

日本癌学会総会記事　Vol. 82回　p. 1008-1008　2023/09

Disseminated non-tuberculous mycobacterial infection caused by Mycobacterium obuense in an immunocompromised patient: a case report.

Maiko Naito, Kentaro Fukushima, Shinsuke Kusakabe, Takaya Endo, Takayuki Shiroyama, Kika Ohira, Koji Azuma, Satoshi Tanizaki, Yumiko Yamamoto, Yuki Hosono, Yujiro Naito, Shinji Futami, Kotaro Miyake, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

BMC infectious diseases　Vol. 23　No. 1　p. 517-517　2023/08/08　Research paper (scientific journal)

胸腺小細胞癌の1例

内藤 真依子, 細野 裕貴, 東 浩志, 大平 貴華, 山本 有美子, 谷崎 智史, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 武田 吉人, 熊ノ郷 淳

肺癌　Vol. 63　No. 3　p. 263-263　2023/06

悪性軟部腫瘍の縦隔リンパ節転移により気道圧排を伴った1例

東 浩志, 谷崎 智史, 大平 貴華, 山本 有美子, 細野 裕貴, 内藤 真依子, 白山 敬之, 平田 陽彦, 武田 吉人, 熊ノ郷 淳

肺癌　Vol. 63　No. 3　p. 265-265　2023/06

気管支ナビゲーションの現状・将来 オブリーク法を搭載した新しいDirectPathシステムの初期評価について

谷崎 智史, 三宅 浩太郎, 大平 貴華, 山本 有美子, 東 浩志, 細野 裕貴, 内藤 真依子, 二見 真史, 内藤 祐二朗, 福島 清春, 白山 敬之, 小山 正平, 平田 陽彦, 岩堀 幸太, 長友 泉, 武田 吉人, 熊ノ郷 淳

気管支学　Vol. 45　No. Suppl.　p. S185-S185　2023/06

薬剤性ループス治療中に発症したInvasive tracheobronchial aspergillosisの一例

久下 朋輝, 三宅 浩太郎, 矢賀 元, 白山 敬之, 小山 正平, 岩堀 幸太, 平田 陽彦, 長友 泉, 武田 吉人

気管支学　Vol. 45　No. Suppl.　p. S283-S283　2023/06

肺・胸腺非定型カルチノイドに対してルテチウム(177Lu)オキソドトレオチド(ルタテラ)を使用した2例

谷崎 智史, 平田 陽彦, 大平 貴華, 東 浩志, 山本 有美子, 細野 裕貴, 内藤 真依子, 二見 真史, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 小山 正平, 福島 清春, 岩堀 幸太, 長友 泉, 武田 吉人, 熊ノ郷 淳

肺癌　Vol. 63　No. 3　p. 265-266　2023/06

Impact of minocycline on outcomes of EGFR-mutant non-small cell lung cancer patients treated with EGFR-TKIs.

Mari Tone, Kota Iwahori, Takayuki Shiroyama, Shinji Futami, Yujiro Naito, Kiyoharu Fukushima, Kotaro Miyake, Shohei Koyama, Haruhiko Hirata, Izumi Nagatomo, Hisashi Wada, Yoshito Takeda, Atsushi Kumanogoh

Scientific reports　Vol. 13　No. 1　p. 8313-8313　2023/05/23　Research paper (scientific journal)

Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation.

Yujiro Naito, Shohei Koyama, Kentaro Masuhiro, Takashi Hirai, Takeshi Uenami, Takako Inoue, Akio Osa, Hirotomo Machiyama, Go Watanabe, Nicolas Sax, Jordan Villa, Yumi Kinugasa-Katayama, Satoshi Nojima, Moto Yaga, Yuki Hosono, Daisuke Okuzaki, Shingo Satoh, Takeshi Tsuda, Yoshimitsu Nakanishi, Yasuhiko Suga, Takayoshi Morita, Kiyoharu Fukushima, Masayuki Nishide, Takayuki Shiroyama, Kotaro Miyake, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yukihiro Yano, Motohiro Tamiya, Toru Kumagai, Norihiko Takemoto, Hidenori Inohara, Sho Yamasaki, Kazuo Yamashita, Taiki Aoshi, Esra A Akbay, Naoki Hosen, Yasushi Shintani, Hyota Takamatsu, Masahide Mori, Yoshito Takeda, Atsushi Kumanogoh

Science advances　Vol. 9　No. 20　2023/05/19　Research paper (scientific journal)

Impact of Lymphopenia Recovery After Chemoradiotherapy on Durvalumab Consolidation Therapy in Stage III NSCLC.

Tomoki Kuge, Takayuki Shiroyama, Akihiro Tamiya, Motohiro Tamiya, Masaki Kanazu, Yuhei Kinehara, Tsunehiro Tanaka, Osamu Morimura, Yoshihiko Taniguchi, Toshie Niki, Satoshi Tetsumoto, Kazuhiko Hayashi, Kazumi Nishino, Izumi Nagatomo, Atsushi Kumanogoh

JTO clinical and research reports　Vol. 4　No. 5　p. 100505-100505　2023/05　Research paper (scientific journal)

縦隔・胸膜疾患 エクソソームの次世代プロテオミクスによる悪性胸膜中皮腫の新規バイオマーカー開発

安部 祐子, 武田 吉人, 福島 清春, 白山 敬之, 平田 陽彦, 足立 淳, 伊藤 眞里, 横井 崇, 南 俊行, 栗林 康造, 木島 貴志, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 187-187　2023/03

肺癌 効果予測因子 血清エクソソームの最新プロテオミクスによる小細胞肺癌の新規バイオマーカーの探索

山本 真, 菅 泰彦, 武田 吉人, 中坪 大亮, 榎本 貴俊, 吉村 華子, 網屋 沙織, 原 伶奈, 川崎 貴裕, 白山 敬之, 三宅 浩太郎, 伊藤 眞里, 足立 淳, 上條 陽平, 澤田 隆介, 山西 芳裕, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 194-194　2023/03

原発性腸リンパ管拡張症に合併した乳糜胸水に対して胸膜癒着術が奏功した一例

山本 有美子, 二見 真史, 谷崎 智史, 東 浩志, 大平 貴華, 細野 裕貴, 内藤 真依子, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 233-233　2023/03

同定不能抗酸菌と誤同定された新種Tsukamurella toyonakaenseによる慢性肺感染の一例

久下 朋輝, 福島 清春, 安部 祐子, 川崎 貴裕, 松木 隆典, 白山 敬之, 辻野 和之, 三木 啓資, 森 雅秀, 北田 清悟, 木田 博, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 247-247　2023/03

胸腺小細胞癌の2例

内藤 真依子, 細野 裕貴, 東 浩志, 大平 貴華, 山本 有美子, 谷崎 智史, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 255-255　2023/03

播種性ノカルジア症を契機に診断された慢性肉芽腫症の1例

西川 祐樹, 白井 雄也, 二見 真史, 内藤 祐二朗, 三宅 浩太郎, 白山 敬之, 平田 陽彦, 武田 吉人, 和田 泰三, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 385-385　2023/03

オシロメトリーによる気腫合併肺線維症の換気能と肺拡散能の評価

山本 悠司, 平田 陽彦, 白山 敬之, 久下 朋輝, 松本 錦之介, 米田 翠, 山本 真, 内藤 祐二朗, 菅 泰彦, 福島 清春, 三宅 浩太郎, 小山 正平, 岩堀 幸太, 長友 泉, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 214-214　2023/03

当院での固形臓器移植後患者におけるCOVID-19の経過 18例の後方視的検討

谷崎 智史, 平田 陽彦, 大平 貴華, 東 浩志, 山本 有美子, 細野 裕貴, 内藤 真依子, 二見 真史, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 福島 清春, 小山 正平, 岩堀 幸太, 長友 泉, 武田 吉人, 狩野 孝, 新谷 康, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 245-245　2023/03

エクソソームの次世代プロテオミクスによる気管支喘息T2炎症の新規BM開発

吉村 華子, 武田 吉人, 榎本 貴俊, 原 伶奈, 山本 真, 内藤 祐二朗, 二見 真史, 白山 敬之, 平田 陽彦, 小山 正平, 長友 泉, 岩堀 幸太, 足立 淳, 夏目 やよい, 伊藤 眞里, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 312-312　2023/03

Virtual fluoroscopic preprocedural planning using Ziostation2 for transbronchial biopsy: A prospective self-controlled study.

Yuko Abe, Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Respiratory investigation　Vol. 61　No. 2　p. 157-163　2023/03　Research paper (scientific journal)

Secondary subcutaneous abscess due to mixed infections by Peptoniphilus olsenii and Gleimia europaea after COVID-19.

Yuji Yamamoto, Takayuki Shiroyama, Haruhiko Hirata, Kinnosuke Matsumoto, Tomoki Kuge, Midori Yoneda, Makoto Yamamoto, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Clinical case reports　Vol. 11　No. 1　2023/01　Research paper (scientific journal)

Real-world impact of antifibrotics on prognosis in patients with progressive fibrosing interstitial lung disease.

Takayuki Niitsu, Kiyoharu Fukushima, Sho Komukai, So Takata, Yuko Abe, Takuro Nii, Tomoki Kuge, Shinichi Iwakoshi, Takayuki Shiroyama, Kotaro Miyake, Kazuyuki Tujino, Satoshi Tanizaki, Kota Iwahori, Haruhiko Hirata, Keisuke Miki, Masahiro Yanagawa, Noriyuki Takeuchi, Yoshito Takeda, Hiroshi Kida, Atsushi Kumanogoh

RMD open　Vol. 9　No. 1　2023/01　Research paper (scientific journal)

Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19.

Takahiro Kawasaki, Yoshito Takeda, Ryuya Edahiro, Yuya Shirai, Mari Nogami-Itoh, Takanori Matsuki, Hiroshi Kida, Takatoshi Enomoto, Reina Hara, Yoshimi Noda, Yuichi Adachi, Takayuki Niitsu, Saori Amiya, Yuta Yamaguchi, Teruaki Murakami, Yasuhiro Kato, Takayoshi Morita, Hanako Yoshimura, Makoto Yamamoto, Daisuke Nakatsubo, Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Jun Adachi, Yukinori Okada, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 42　No. 1　p. 53-53　2022/11/30　Research paper (scientific journal)

Proposal of a novel pipeline involving precise bronchoscopy of distal peripheral pulmonary lesions for genetic testing.

So Takata, Kotaro Miyake, Daichi Maeda, Kazue Hatake, Izumi Nagatomo, Takayuki Shiroyama, Kentaro Masuhiro, Moto Yaga, Yuya Shirai, Yuichi Mitsui, Shinichi Yachida, Atsushi Kumanogoh

Scientific reports　Vol. 12　No. 1　p. 19774-19774　2022/11/17　Research paper (scientific journal)

がんにおけるSNRPD3変異の意義の解明

佐藤 真吾, 三宅 浩太郎, 内藤 祐二朗, 菅 泰彦, 白山 敬之, 小山 正平, 平田 陽彦, 長友 泉, 武田 吉人, 熊ノ郷 淳

肺癌　Vol. 62　No. 6　p. 752-752　2022/11

エクソソームの次世代プロテオミクスによる悪性胸膜中皮腫の新規バイオマーカー開発

安部 祐子, 武田 吉人, 山本 真, 福島 清春, 白山 敬之, 平田 陽彦, 足立 淳, 伊藤 眞里, 横井 崇, 南 俊行, 栗林 康造, 木島 貴志, 熊ノ郷 淳

肺癌　Vol. 62　No. 6　p. 755-755　2022/11

【COVID-19パンデミック-他の疾患に及ぼす影響】ウイルス性呼吸器疾患に及ぼす影響

山口 蒼生, 加藤 保宏, 白山 敬之, 熊ノ郷 淳

臨床と微生物　Vol. 49　No. 6　p. 673-679　2022/11　Research paper (scientific journal)

Peripheral T cell cytotoxicity predicts the efficacy of anti-PD-1 therapy for advanced non-small cell lung cancer patients

Kota Iwahori, Takeshi Uenami, Yukihiro Yano, Toshihiko Ueda, Mari Tone, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Takayuki Shiroyama, Kotaro Miyake, Shohei Koyama, Haruhiko Hirata, Izumi Nagatomo, Hiroshi Kida, Masahide Mori, Yoshito Takeda, Atsushi Kumanogoh, Hisashi Wada

Scientific Reports　Vol. 12　No. 1　2022/10/19　Research paper (scientific journal)

エクソソームのプロテオミクスによる悪性胸膜中皮腫の新規バイオマーカーの同定(Identification of novel biomarkers for malignant pleural mesothelioma by proteomics of serum exosomes)

安部 祐子, 武田 吉人, 福島 清春, 白山 敬之, 平田 陽彦, 横井 崇, 南 俊行, 栗林 康造, 木島 貴志, 足立 淳, 熊ノ郷 淳

日本癌学会総会記事　Vol. 81回　p. P-2136　2022/09

Impact of treatment line on risks and benefits of immune checkpoint inhibitor in patients with advanced non-small cell lung cancer and interstitial lung disease: a systematic review and meta-analysis of cohort studies

Kinnosuke Matsumoto, Takayuki Shiroyama, Tomoki Kuge, Kotaro Miyake, Yuji Yamamoto, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Translational Lung Cancer Research　Vol. 11　No. 9　p. 1835-1846　2022/09　Research paper (scientific journal)

Lateral Decubitus Position Enables Further Advancement of the Bronchoscope into the Lung Periphery.

Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Journal of bronchology & interventional pulmonology　Vol. 29　No. 4　p. 307-310　2022/07/26　Research paper (scientific journal)

CpG ODN (K3)-toll-like receptor 9 agonist-induces Th1-type immune response and enhances cytotoxic activity in advanced lung cancer patients: a phase I study.

Tomoyuki Otsuka, Sumiyuki Nishida, Takayuki Shibahara, Burcu Temizoz, Masanari Hamaguchi, Takayuki Shiroyama, Keiko Kimura, Kotaro Miyake, Haruhiko Hirata, Yumiko Mizuno, Mayu Yagita, Yusuke Manabe, Etsushi Kuroda, Yoshito Takeda, Hiroshi Kida, Ken J Ishii, Atsushi Kumanogoh

BMC cancer　Vol. 22　No. 1　p. 744-744　2022/07/07　Research paper (scientific journal)

Respiratory Impedance is Associated with Ventilation and Diffusing Capacity in Patients with Idiopathic Pulmonary Fibrosis Combined with Emphysema

Yuji Yamamoto, Haruhiko Hirata, Takayuki Shiroyama, Tomoki Kuge, Kinnosuke Matsumoto, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Kotaro Miyake, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

International Journal of Chronic Obstructive Pulmonary Disease　Vol. Volume 17　p. 1495-1506　2022/07　Research paper (scientific journal)

Impact of the Treatment Line on the Risks and Benefits of Immune Checkpoint Inhibitors in Patients With Non-Small Cell Lung Cancer and Interstitial Lung Disease.

Kinnosuke Matsumoto, Takayuki Shiroyama, Yuji Yamamoto, Kotaro Miyake, Yoshito Takeda, Atsushi Kumanogoh

Chest　Vol. 162　No. 1　2022/07　Research paper (scientific journal)

Chronic Pulmonary Disease Caused by Tsukamurella toyonakaense.

Tomoki Kuge, Kiyoharu Fukushima, Yuki Matsumoto, Haruko Saito, Yuko Abe, Eri Akiba, Kako Haduki, Tadayoshi Nitta, Akira Kawano, Michio Tanaka, Yumi Hattori, Takahiro Kawasaki, Takanori Matsuki, Takayuki Shiroyama, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Masahide Mori, Seigo Kitada, Shota Nakamura, Tetsuya Iida, Atsushi Kumanogoh, Hiroshi Kida

Emerging infectious diseases　Vol. 28　No. 7　p. 1437-1441　2022/07　Research paper (scientific journal)

Quantitative evaluation of emphysema for predicting immunotherapy response in patients with advanced non-small-cell lung cancer.

Yoshimi Noda, Takayuki Shiroyama, Kentaro Masuhiro, Saori Amiya, Takatoshi Enomoto, Yuichi Adachi, Reina Hara, Takayuki Niitsu, Yujiro Naito, Kotaro Miyake, Shohei Koyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Scientific reports　Vol. 12　No. 1　p. 8881-8881　2022/05/25　Research paper (scientific journal)

微小生検検体の厚切りと薄切枚数増加によるOncomineTM Target Testの実現

高田 創, 三宅 浩太郎, 白井 雄也, 光井 雄一, 益弘 健太朗, 矢賀 元, 白山 敬之, 小山 正平, 岩堀 幸太, 平田 陽彦, 長友 泉, 武田 吉人

気管支学　Vol. 44　No. Suppl.　p. S270-S270　2022/05

Leucine-rich a-2 glycoprotein as a potential biomarker of idiopathic multicentric Castleman disease with pulmonary involvement: a single-center case-control study from Japan.

So Takata, Yoshito Takeda, Haruhiko Hirata, Yuya Shirai, Takayoshi Morita, Yu Futami, Yujiro Naito, Kentaro Masuhiro, Takayuki Shiroyama, Kotaro Miyake, Tetsuji Naka, Atsushi Kumanogoh

Journal of thoracic disease　Vol. 14　No. 5　p. 1332-1341　2022/05　Research paper (scientific journal)

Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer.

Kentaro Masuhiro, Motohiro Tamiya, Kosuke Fujimoto, Shohei Koyama, Yujiro Naito, Akio Osa, Takashi Hirai, Hidekazu Suzuki, Norio Okamoto, Takayuki Shiroyama, Kazumi Nishino, Yuichi Adachi, Takuro Nii, Yumi Kinugasa-Katayama, Akiko Kajihara, Takayoshi Morita, Seiya Imoto, Satoshi Uematsu, Takuma Irie, Daisuke Okuzaki, Taiki Aoshi, Yoshito Takeda, Toru Kumagai, Tomonori Hirashima, Atsushi Kumanogoh

JCI insight　Vol. 7　No. 9　2022/04/07　Research paper (scientific journal)

びまん性肺疾患 診断・バイオマーカー 「PRISM」データから見えてきた新たな線維化バイオマーカー

白井 雄也, 武田 吉人, 榎本 貴俊, 足立 雄一, 網屋 沙織, 野田 成美, 菅 泰彦, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 足立 淳, 夏目 やよい, 伊藤 眞里, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 145-145　2022/04

びまん性肺疾患 診断・バイオマーカー エクソソームの次世代プロテオミクスによるサルコイドーシスの新規バイオマーカー探索(PRISM)

網屋 沙織, 武田 吉人, 榎本 貴俊, 白井 雄也, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 足立 淳, 伊藤 眞里, 夏目 やよい, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 145-145　2022/04

免疫チェックポイント阻害薬 気管支肺胞洗浄液を用いた肺癌免疫微小環境の解析による抗PD-1抗体効果予測因子の探索

益弘 健太朗, 田宮 基裕, 藤本 康介, 内藤 祐二朗, 小山 正平, 白山 敬之, 井上 貴子, 西野 和美, 鈴木 秀和, 岡本 紀雄, 平島 智徳, 熊谷 融, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 156-156　2022/04

呼吸器悪性疾患におけるバイオマーカー エクソソームのプロテオミクスを用いた肺小細胞癌における新規バイオマーカー探索

菅 泰彦, 吉村 華子, 内藤 祐二朗, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 長友 泉, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 158-158　2022/04

呼吸器悪性疾患におけるバイオマーカー エクソソームの次世代プロテオミクスによる悪性胸膜中皮腫の新規バイオマーカー探索

安部 祐子, 武田 吉人, 福島 清春, 白山 敬之, 平田 陽彦, 足立 淳, 伊藤 眞里, 横井 崇, 南 俊行, 栗林 康造, 木島 貴志, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 158-158　2022/04

呼吸器悪性疾患におけるバイオマーカー がんにおけるSNRPD3変異の意義の解明

佐藤 真吾, 三宅 浩太郎, 内藤 祐二朗, 菅 泰彦, 福島 清春, 白山 敬之, 小山 正平, 平田 陽彦, 岩堀 幸太, 長友 泉, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 158-158　2022/04

EGFR遺伝子変異陽性肺癌患者におけるミノマイシン内服の予後への影響

刀祢 麻里, 岩堀 幸太, 白山 敬之, 内藤 祐二朗, 菅 泰彦, 福島 清春, 三宅 浩太郎, 小山 正平, 平田 陽彦, 長友 泉, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 305-305　2022/04

Data-driven patient stratification and drug target discovery by using medical information and serum proteome data of idiopathic pulmonary fibrosis patients

Yayoi Natsume-Kitatani, Mari N Itoh, Yoshito Takeda, Masataka Kuroda, Haruhiko Hirata, Kohtaro Miyake, Takayuki Shiroyama, Yuya Shirai, Yoshimi Noda, Yuichi Adachi, Takatoshi Enomoto, Saori Amiya, Jun Adachi, Ryohei Narumi, Satoshi Muraoka, Takeshi Tomonaga, Sadao Kurohashi, Fei Cheng, Ribeka Tanaka, Shuntaro Yada, Eiji Aramaki, Shoko Wakamiya, Yi-An Chen, Chihiro Higuchi, Yosui Nojima, Takeshi Fujiwara, Chioko Nagao, Yasushi Matsumura, Kenji Mizuguchi, Atsushi Kumanogoh, Naonori Ueda

2022/03/29

COVID-19 in a human T-cell lymphotropic virus type-1 carrier.

Takatoshi Enomoto, Takayuki Shiroyama, Haruhiko Hirata, Saori Amiya, Yuichi Adachi, Takayuki Niitsu, Yoshimi Noda, Reina Hara, Kiyoharu Fukushima, Yasuhiko Suga, Kotaro Miyake, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Natsuko Tokuhira, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Clinical case reports　Vol. 10　No. 2　2022/02

Case report: Acute exacerbation of interstitial pneumonia related to messenger RNA COVID-19 vaccination.

Saori Amiya, Jun Fujimoto, Kinnosuke Matsumoto, Makoto Yamamoto, Yuji Yamamoto, Midori Yoneda, Tomoki Kuge, Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases　Vol. 116　p. 255-257　2022/01/19

Management of severe hypertension due to lenvatinib in patients with advanced thymic carcinoma: A case report.

Kinnosuke Matsumoto, Takayuki Shiroyama, Kotaro Miyake, Yuji Yamamoto, Tomoki Kuge, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Medicine　Vol. 101　No. 1　2022/01/07　Research paper (scientific journal)

Identification of CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis using proteomics of serum extracellular vesicles

Futami, Yu, Takeda, Yoshito, Koba, Taro, Narumi, Ryohei, Nojima, Yosui, Ito, Mari, Nakayama, Mana, Ishida, Mimiko, Yoshimura, Hanako, Naito, Yujiro, Fukushima, Kiyoharu, Takimoto, Takayuki, Edahiro, Ryuya, Matsuki, Takanori, Nojima, Satoshi, Hirata, Haruhiko, Koyama, Shohei, Iwahori, Kota, Nagatomo, Izumi, Shirai, Yuya, Suga, Yasuhiko, Satoh, Shingo, Futami, Shinji, Miyake, Kotaro, Shiroyama, Takayuki, Inoue, Yoshikazu, Adachi, Jun, Tomonaga, Takeshi, Ueda, Koji, Kumanogoh, Atsushi

International immunology　2022　Research paper (scientific journal)

A case of synchronous triple autoimmune disorders secondary to thymoma: Pure red cell aplasia, Good's syndrome, and thymoma-associated multi-organ autoimmunity.

Yuta Nakagawa, Kinnosuke Matsumoto, Makoto Yamamoto, Haruhiko Hirata, Takayuki Shiroyama, Kotaro Miyake, Yuji Yamamoto, Tomoki Kuge, Midori Yoneda, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Respiratory medicine case reports　Vol. 36　p. 101619-101619　2022　Research paper (scientific journal)

Lipoid Pneumonia After Pembrolizumab Treatment for Advanced Non-Small-Cell Lung Cancer.

Moto Yaga, Takayuki Shiroyama, Haruhiko Hirata, Kaori Oya, Yoshito Takeda, Atsushi Kumanogoh

Clinical lung cancer　2021/12/10

Impact of treatment timing and sequence of immune checkpoint inhibitors and anti-angiogenic agents for advanced non-small cell lung cancer: A systematic review and meta-analysis.

Kinnosuke Matsumoto, Takayuki Shiroyama, Tomoki Kuge, Kotaro Miyake, Yuji Yamamoto, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Lung cancer (Amsterdam, Netherlands)　Vol. 162　p. 175-184　2021/12　Research paper (scientific journal)

Prolonged corticosteroid therapy and cytomegalovirus infection in patients with severe COVID-19.

Yuji Yamamoto, Takayuki Shiroyama, Haruhiko Hirata, Tomoki Kuge, Kinnosuke Matsumoto, Midori Yoneda, Makoto Yamamoto, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Journal of medical virology　2021/10/28　Research paper (scientific journal)

血清エクソソームの次世代プロテオミクスによるサルコイドーシスの新規バイオマーカー同定

網屋 沙織, 武田 吉人, 足立 雄一, 榎本 貴俊, 新津 敬之, 野田 成美, 白井 雄也, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 足立 淳, 伊藤 眞里, 夏目 やよい, 熊ノ郷 淳, 井上 義一

日本サルコイドーシス/肉芽腫性疾患学会雑誌　Vol. 41　No. サプリメント号　p. 62-62　2021/10

EGFRエクソン20の挿入変異遺伝子配列を参考にしてEGFR-TKIの選択を行い、オシメルチニブが奏功した肺腺癌の1例

榎本 貴俊, 平田 陽彦, Tansri Wibowo, 新津 敬之, 野田 成美, 原 伶奈, 足立 雄一, 網屋 沙織, 内藤 祐二朗, 菅 泰彦, 三宅 浩太郎, 白山 敬之, 武田 吉人, 熊ノ郷 淳

肺癌　Vol. 61　No. 5　p. 448-448　2021/10

Cytomegalovirus infection in critically ill patients with COVID-19.

Takayuki Niitsu, Takayuki Shiroyama, Haruhiko Hirata, Yoshimi Noda, Yuichi Adachi, Takatoshi Enomoto, Reina Hara, Saori Amiya, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

The Journal of infection　Vol. 83　No. 4　p. 496-522　2021/10

Opposite response of lung adenocarcinoma and its choroidal metastases upon ramucirumab plus docetaxel therapy after immunotherapy: a case report.

Kinnosuke Matsumoto, Takayuki Shiroyama, Noriyasu Hashida, Kotaro Miyake, Yuji Yamamoto, Tomoki Kuge, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Angiogenesis　Vol. 25　No. 2　p. 147-149　2021/09/30

エクソソームのプロテオミクスによる悪性胸膜中皮腫の新規バイオマーカー探索

安部 祐子, 武田 吉人, 榎本 貴俊, 吉村 華子, 菅 泰彦, 福島 清春, 白山 敬之, 平田 陽彦, 横井 崇, 南 俊行, 栗林 康造, 木島 貴志, 熊ノ郷 淳

日本癌学会総会記事　Vol. 80回　p. [P14-5]　2021/09

IL-33 Induces Sema4A Expression in Dendritic Cells and Exerts Antitumor Immunity.

Yasuhiko Suga, Izumi Nagatomo, Yuhei Kinehara, Shohei Koyama, Daisuke Okuzaki, Akio Osa, Yujiro Naito, Hyota Takamatsu, Masayuki Nishide, Satoshi Nojima, Daisuke Ito, Takeshi Tsuda, Takeshi Nakatani, Yoshimitsu Nakanishi, Yu Futami, Taro Koba, Shingo Satoh, Yuki Hosono, Kotaro Miyake, Kiyoharu Fukushima, Takayuki Shiroyama, Kota Iwahori, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 207　No. 5　p. 1456-1467　2021/09/01　Research paper (scientific journal)

Phase 2 study of bevacizumab plus carboplatin/nab-paclitaxel followed by bevacizumab plus nab-paclitaxel for non-squamous non-small cell lung cancer with malignant pleural effusion.

Motohiro Tamiya, Akihiro Tamiya, Hidekazu Suzuki, Yoshihiko Taniguchi, Kanako Katayama, Shojiro Minomo, Keiko Nakao, Naoko Takeuchi, Yoshinobu Matsuda, Yujiro Naito, Takayuki Shiroyama, Norio Okamoto, Kyoichi Okishio, Toru Kumagai, Shinji Atagi, Fumio Imamura, Tomonori Hirashima

Investigational new drugs　Vol. 39　No. 4　p. 1106-1112　2021/08　Research paper (scientific journal)

Fatal cytomegalovirus pneumonia in a critically ill patient with COVID-19.

Saori Amiya, Haruhiko Hirata, Takayuki Shiroyama, Yuichi Adachi, Takayuki Niitsu, Yoshimi Noda, Takatoshi Enomoto, Reina Hara, Kiyoharu Fukushima, Yasuhiko Suga, Kotaro Miyake, Moe Koide, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Respirology case reports　Vol. 9　No. 7　2021/07

CD14 and LBP as Novel Biomarkers for Sarcoidosis by Proteomics of Extracellular Vesicles

Yu Futami, Yoshito Takeda, Taro Koba, Ryohei Narumi, Yosui Nojima, Mari Ito, Mana Nakayama, Mimiko Ishida, Hanako Yoshimura, Yujiro Naito, Kiyoharu Fukushima, Takayuki Takimoto, Ryuya Edahiro, Tomonori Matsuki, Satoshi Nojima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yuya Shirai, Yasuhiko Suga, Shingo Satoh, Shinji Futami, Kotaro Miyake, Takayuki Shiroyama, Yoshikazu Inoue, Jun Adachi, Takeshi Tomonaga, Koji Ueda, Atsushi Kumanogoh

International Immunology　Vol. 34　No. 6　p. 327-340　2021/06/04

Transbronchial cryobiopsy for miliary tuberculosis mimicking hypersensitivity pneumonitis

Shingo Nasu, Kunimitsu Kawahara, Yuki Han, Norio Okamoto, Yoshitaka Tamura, Hidekazu Suzuki, Takayuki Shiroyama, Yumiko Samejima, Tomohiro Kanai, Yoshimi Noda, Ayako Tanaka, Naoko Morishita, Kayo Ueda, Shoji Hashimoto, Tomonori Hirashima, Takayuki Nagai

Internal Medicine　Vol. 60　No. 3　p. 445-448　2021/02/01　Research paper (scientific journal)

COVID-19 in a patient with sporadic lymphangioleiomyomatosis awaiting lung transplantation.

Yoshimi Noda, Takayuki Shiroyama, Saori Amiya, Yuichi Adachi, Takatoshi Enomoto, Reina Hara, Takayuki Niitsu, Kotaro Miyake, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

Respiratory medicine case reports　Vol. 34　p. 101505-101505　2021

Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres

Taro Koba, Yoshito Takeda, Ryohei Narumi, Takashi Shiromizu, Yosui Nojima, Mari Ito, Muneyoshi Kuroyama, Yu Futami, Takayuki Takimoto, Takanori Matsuki, Ryuya Edahiro, Satoshi Nojima, Yoshitomo Hayama, Kiyoharu Fukushima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Mayumi Suzuki, Yuya Shirai, Teruaki Murakami, Kaori Nakanishi, Takeshi Nakatani, Yasuhiko Suga, Kotaro Miyake, Takayuki Shiroyama, Hiroshi Kida, Takako Sasaki, Koji Ueda, Kenji Mizuguchi, Jun Adachi, Takeshi Tomonaga, Atsushi Kumanogoh

ERJ Open Research　Vol. 7　No. 1　p. 00658-2020　2021/01　Research paper (scientific journal)

Predicting recurrence of respiratory failure in critically ill patients with COVID-19: A preliminary study

Yuichi Adachi, Takayuki Shiroyama, Yuta Yamaguchi, Teruaki Murakami, Haruhiko Hirata, Saori Amiya, Takayuki Niitsu, Yoshimi Noda, Reina Hara, Takatoshi Enomoto, Takayoshi Morita, Yasuhiro Kato, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Journal of Infection　Vol. 82　No. 5　p. e33-e35　2021/01　Research paper (scientific journal)

Combined small cell lung carcinoma harboring ALK rearrangement: A case report and literature review.

Takayuki Niitsu, Takayuki Shiroyama, Kotaro Miyake, Yoshimi Noda, Kansuke Kido, Reina Hara, Takatoshi Enomoto, Yuichi Adachi, Saori Amiya, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Thoracic cancer　Vol. 11　No. 12　p. 3625-3630　2020/12　Research paper (scientific journal)

Effectiveness of EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer patients with uncommon EGFR mutations: A multicenter observational study.

Masaki Kanazu, Masahide Mori, Madoka Kimura, Kazumi Nishino, Takayuki Shiroyama, Izumi Nagatomo, Shoichi Ihara, Kiyoshi Komuta, Hidekazu Suzuki, Tomonori Hirashima, Toru Kumagai, Fumio Imamura

Thoracic cancer　Vol. 12　No. 1　p. 90-96　2020/10/29　Research paper (scientific journal)

Pulmonary metastases of lung adenocarcinoma mimicking COVID-19 pneumonia.

Takayuki Shiroyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Journal of thoracic disease　Vol. 12　No. 10　p. 6125-6126　2020/10　Research paper (scientific journal)

A Multivariable Regression Model-based Nomogram for Estimating the Overall Survival of Patients Previously Treated With Nivolumab for Advanced Non-small-cell Lung Cancer.

Akihiro Tamiya, Motohiro Tamiya, Hirofumi Go, Takako Inoue, Kei Kunimasa, Kenji Nakahama, Yoshihiko Taniguchi, Takayuki Shiroyama, Shun-Ichi Isa, Kazumi Nishino, Toru Kumagai, Hidekazu Suzuki, Tomonori Hirashima, Shinji Atagi, Ayumi Shintani, Fumio Imamura

Anticancer research　Vol. 40　No. 8　p. 4229-4236　2020/08　Research paper (scientific journal)

Real-world osimertinib for EGFR mutation-positive non-small-cell lung cancer with acquired T790M mutation.

Fumio Imamura, Madoka Kimura, Yukihiro Yano, Masahide Mori, Hidekazu Suzuki, Tomonori Hirashima, Shouichi Ihara, Kiyoshi Komuta, Takayuki Shiroyama, Izumi Nagatomo, Toru Kumagai

Future oncology (London, England)　Vol. 16　No. 21　p. 1537-1547　2020/07　Research paper (scientific journal)

Safety and efficacy of afatinib for the treatment of non-small-cell lung cancer following osimertinib-induced interstitial lung disease: A retrospective study.

Shingo Nasu, Hidekazu Suzuki, Takayuki Shiroyama, Ayako Tanaka, Yumiko Samejima, Tomohiro Kanai, Yoshimi Noda, Naoko Morishita, Norio Okamoto, Tomonori Hirashima

Investigational new drugs　2020/06/15　Research paper (scientific journal)

Tree-in-bud Pattern in ALK-positive Lung Adenocarcinoma.

Takayuki Shiroyama, Shingo Nasu, Ayako Tanaka, Tomonori Hirashima

Internal medicine (Tokyo, Japan)　Vol. 59　No. 11　p. 1461-1461　2020/06/01　Research paper (scientific journal)

Severe myocarditis with slight lymphocytic infiltration after nivolumab treatment.

Ryuya Edahiro, Takayuki Shiroyama, Sachiko Hijiki, Satoshi Nojima, Yuya Shirai, Shohei Koyama, Atsushi Kumanogoh

Lung cancer (Amsterdam, Netherlands)　Vol. 140　p. 116-117　2020/02

Monitoring antibody binding to T cells in a pembrolizumab-treated patient with lung adenocarcinoma on hemodialysis.

Akio Osa, Takeshi Uenami, Yujiro Naito, Haruhiko Hirata, Shohei Koyama, Takayuki Takimoto, Takayuki Shiroyama, Shinji Futami, Saeko Nakatsubo, Nobuhiko Sawa, Yukihiro Yano, Izumi Nagatomo, Yoshito Takeda, Masahide Mori, Hiroshi Kida, Atsushi Kumanogoh

Thoracic cancer　Vol. 10　No. 11　p. 2183-2187　2019/11

Comparison of the Utilities of Cryobiopsy and Forceps Biopsy for Peripheral Lung Cancer.

Shingo Nasu, Norio Okamoto, Hidekazu Suzuki, Takayuki Shiroyama, Ayako Tanaka, Yumiko Samejima, Tomohiro Kanai, Yoshimi Noda, Satomu Morita, Naoko Morishita, Kayo Ueda, Kunimitsu Kawahara, Tomonori Hirashima

Anticancer research　Vol. 39　No. 10　p. 5683-5688　2019/10　Research paper (scientific journal)

A Phase II Study of Tailored-dose S-1 Plus Carboplatin Followed by Maintenance S-1 for Advanced Squamous Cell Lung Cancer: OSAKA-LCSG 1102.

Yokoi T, Minami S, Shiroyama T, Koba T, Torii Y, Sugimoto H, Niki M, Mori M, Morimura O, Hirashima T, Komuta K, Kijima T

Internal medicine (Tokyo, Japan)　Vol. 58　No. 10　p. 1405-1410　2019/05

Unique Case of Pseudoprogression Manifesting as Lung Cavitation After Pembrolizumab Treatment.

Kentaro Masuhiro, Takayuki Shiroyama, Izumi Nagatomo, Atsushi Kumanogoh

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer　Vol. 14　No. 5　p. e108-e109-e109　2019/05

Impact of sarcopenia in patients with advanced non-small cell lung cancer treated with PD-1 inhibitors: A preliminary retrospective study.

Takayuki Shiroyama, Izumi Nagatomo, Shohei Koyama, Haruhiko Hirata, Sumiyuki Nishida, Kotaro Miyake, Kiyoharu Fukushima, Yuya Shirai, Yuichi Mitsui, So Takata, Kentaro Masuhiro, Moto Yaga, Kota Iwahori, Yoshito Takeda, Hiroshi Kida, Atsushi Kumanogoh

Scientific reports　Vol. 9　No. 1　p. 2447-2447　2019/02/21　Research paper (scientific journal)

Re-challenge chemotherapy in patients with sensitive relapse small-cell lung cancer and interstitial lung disease.

Shingo Nasu, Hidekazu Suzuki, Kazunori Moriizumi, Yuki Hara, Satoshi Tanaka, Hiromune Takada, Satomu Morita, Ayako Tanaka, Takayuki Shiroyama, Naoko Morishita, Norio Okamoto, Tomonori Hirashima

Journal of thoracic disease　Vol. 11　No. 2　p. 514-520　2019/02　Research paper (scientific journal)

Paradoxical response in a patient with non-small cell lung cancer who received nivolumab followed by anti-Mycobacterium tuberculosis agents.

So Takata, Genju Koh, Yuki Han, Hiroko Yoshida, Takayuki Shiroyama, Hiromune Takada, Kentarou Masuhiro, Shingo Nasu, Satomu Morita, Ayako Tanaka, Syouji Hashimoto, Kiyoaki Uriu, Hidekazu Suzuki, Yoshitaka Tamura, Norio Okamoto, Takayuki Nagai, Tomonori Hirashima

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy　Vol. 25　No. 1　p. 54-58　2019/01　Research paper (scientific journal)

A case of successful concurrent anti-cancer treatment in a patient who developed follicular lymphoma during treatment with afatinib for advanced lung adenocarcinoma.

Kentaro Masuhiro, Genju Koh, So Takata, Shingo Nasu, Hiromune Takada, Satomu Morita, Ayako Tanaka, Takayuki Shiroyama, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Hiromi Kawasumi, Chihiro Konishi, Tomonori Hirashima

Respiratory medicine case reports　Vol. 28　p. 100862-100862　2019

Osimertinib Treatment Was Unsuccessful for Lung Adenocarcinoma with G719S, S768I, and T790M Mutations.

Shingo Nasu, Takayuki Shiroyama, Satomu Morita, So Takata, Hiromune Takada, Kentaro Masuhiro, Ayako Tanaka, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Tomonori Hirashima

Internal medicine (Tokyo, Japan)　Vol. 57　No. 24　p. 3643-3645　2018/12/15　Research paper (scientific journal)

Efficacy and safety of concurrent anti-Cancer and anti-tuberculosis chemotherapy in Cancer patients with active Mycobacterium tuberculosis: a retrospective study.

Hirashima T, Tamura Y, Han Y, Hashimoto S, Tanaka A, Shiroyama T, Morishita N, Suzuki H, Okamoto N, Akada S, Fujishima M, Kadota Y, Sakata K, Nishitani A, Miyazaki S, Nagai T

BMC cancer　Vol. 18　No. 1　2018/10

Clinical predictors of bevacizumab-associated intestinal perforation in non-small cell lung cancer.

Motohiro Tamiya, Hidekazu Suzuki, Takayuki Shiroyama, Ayako Tanaka, Naoko Morishita, Norio Okamoto, Kenichi Sakai, Hironori Shigeoka, Kunimitsu Kawahara, Tomonori Hirashima

Investigational new drugs　Vol. 36　No. 4　p. 696-701　2018/08　Research paper (scientific journal)

Clinical Characteristics of Liver Metastasis in Nivolumab-treated Patients with Non-small Cell Lung Cancer.

Shiroyama T, Suzuki H, Tamiya M, Tamiya A, Tanaka A, Okamoto N, Nakahama K, Taniguchi Y, Isa SI, Inoue T, Imamura F, Atagi S, Hirashima T

Anticancer research　Vol. 38　No. 8　p. 4723-4729　2018/08

Association Between Imaging Findings of Airway Obstruction Adjacent to Lung Tumors and the Onset of Interstitial Lung Disease After Nivolumab.

Nakahama K, Tamiya A, Isa SI, Taniguchi Y, Shiroyama T, Suzuki H, Inoue T, Tamiya M, Hirashima T, Imamura F, Atagi S

In vivo (Athens, Greece)　Vol. 32　No. 4　p. 887-891　2018/07

Thoracoscopic Images of Primary Pleural Melanoma.

Takayuki Shiroyama, Shingo Nasu, Satomu Morita, Norio Okamoto

Internal medicine (Tokyo, Japan)　Vol. 57　No. 12　p. 1803-1803　2018/06/15

Impact of Pleural Effusion on Outcomes of Patients Receiving Osimertinib for NSCLC Harboring EGFR T790M.

Kentaro Masuhiro, Takayuki Shiroyama, Hidekazu Suzuki, S O Takata, Shingo Nasu, Hiromune Takada, Satomu Morita, Ayako Tanaka, Naoko Morishita, Norio Okamoto, Tomonori Hirashima

Anticancer research　Vol. 38　No. 6　p. 3567-3571　2018/06　Research paper (scientific journal)

Analysis of Early Death in Japanese Patients With Advanced Non–small-cell Lung Cancer Treated With Nivolumab

Takako Inoue, Motohiro Tamiya, Akihiro Tamiya, Kenji Nakahama, Yoshihiko Taniguchi, Takayuki Shiroyama, Shin-ichi Isa, Kazumi Nishino, Toru Kumagai, Kei Kunimasa, Madoka Kimura, Hidekazu Suzuki, Tomonori Hirashima, Shinji Atagi, Fumio Imamura

Clinical Lung Cancer　Vol. 19　No. 2　p. e219-e226　2018/03/01　Research paper (scientific journal)

Skin Rash Can Be a Useful Marker for Afatinib Efficacy.

Shingo Nasu, Hidekazu Suzuki, Takayuki Shiroyama, Ayako Tanaka, Kaori Iwata, Noriko Ryota, Yuki Ueda, S O Takata, Kentaro Masuhiro, Satomu Morita, Naoko Morishita, Norio Okamoto, Tomonori Hirashima

Anticancer research　Vol. 38　No. 3　p. 1783-1788　2018/03　Research paper (scientific journal)

Metastatic site as a predictor of nivolumab efficacy in patients with advanced non-small cell lung cancer: A retrospective multicenter trial

Motohiro Tamiya, Akihiro Tamiya, Takako Inoue, Madoka Kimura, Kei Kunimasa, Kenji Nakahama, Yoshihiko Taniguchi, Takayuki Shiroyama, Shun-ichi Isa, Kazumi Nishino, Toru Kumagai, Hidekazu Suzuki, Tomonori Hirashima, Shinji Atagi, Fumio Imamura

PLoS ONE　Vol. 13　No. 2　2018/02/01　Research paper (scientific journal)

Differential efficacy of cisplatin plus pemetrexed between L858R and Del-19 in advanced EGFR-mutant non-squamous non-small cell lung cancer

Toshihiko Kaneda, Hiroshige Yoshioka, Motohiro Tamiya, Akihiro Tamiya, Akito Hata, Asukaka Okada, Takashi Niwa, Takayuki Shiroyama, Masaki Kanazu, Tadashi Ishida, Nobuyuki Katakami

BMC Cancer　Vol. 18　No. 1　2018/01/02　Research paper (scientific journal)

Pretreatment advanced lung cancer inflammation index (ALI) for predicting early progression in nivolumab-treated patients with advanced non–small cell lung cancer

Takayuki Shiroyama, Hidekazu Suzuki, Motohiro Tamiya, Akihiro Tamiya, Ayako Tanaka, Norio Okamoto, Kenji Nakahama, Yoshihiko Taniguchi, Shun-Ichi Isa, Takako Inoue, Fumio Imamura, Shinji Atagi, Tomonori Hirashima

Cancer Medicine　Vol. 7　No. 1　p. 13-20　2018/01/01　Research paper (scientific journal)

Successful osimertinib rechallenge after osimertinib-induced pneumonitis in a patient with lung adenocarcinoma.

Shingo Satoh, Takayuki Shiroyama, Motohiro Tamiya, Shingo Nasu, Ayako Tanaka, Satomu Morita, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Tomonori Hirashima

Respiratory medicine case reports　Vol. 23　p. 68-70　2018

Transformation to small cell lung cancer after first-line afatinib treatment.

Takayuki Shiroyama, Shingo Nasu, Ayako Tanaka, So Takata, Kentaro Masuhiro, Hiromune Takada, Satomu Morita, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kunimitsu Kawahara, Tomonori Hirashima

Respiratory medicine case reports　Vol. 23　p. 188-190　2018

Phase1 study of cisplatin plus pemetrexed with erlotinib and bevacizumab for chemotherapy-naïve advanced non-squamous non-small cell lung cancer with EGFR mutations

Motohiro Tamiya, Akihiro Tamiya, Takayuki Shiroyama, Sawa Takeoka, Yujiro Naito, Naoki Omachi, Yohei Kimura, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kyoichi Okishio, Tomoya Kawaguchi, Shinji Atagi, Tomonori Hirashima

Investigational New Drugs　Vol. 36　No. 4　p. 1-7　2017/11/04　Research paper (scientific journal)

CLINICAL ANALYSIS OF AFATINIB IN EGFR-TYROSINE KINASE INHIBITOR NAIVE PATIENTS WITH NON-SMALL CELL LUNG CANCER HABORING EGFR MUTATIONS

Nasu Shingo, Takata So, Masuhiro Kentaro, Morita Satomu, Iwata Kaori, Ryota Noriko, Okada Yukari, Tokuoka Yoshie, Ueda Yuki, Kumode Akinori, Usui Naoko, Tanaka Ayako, Shiroyama Takayuki, Morishita Naoko, Suzuki Hidekazu, Okamoto Norio, Hirashima Tomonori

RESPIROLOGY　Vol. 22　2017/11

Afatinib successfully treated leptomeningeal metastasis during erlotinib treatment in a patient with EGFR-mutant (Exon18:G719S) lung adenocarcinoma as a second-line chemotherapy

Motohiro Tamiya, Takayuki Shiroyama, Takashi Nishihara, Takuji Nishida, Manabu Hayama, Ayako Tanaka, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Tomonori Hirashima

ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY　Vol. 13　No. 5　p. E531-E533　2017/10　Research paper (scientific journal)

Predictive Factors for Poor Progression-free Survival in Patients with Non-small Cell Lung Cancer Treated with Nivolumab

Yoshihiko Taniguchi, Akihiro Tamiya, Syun-Ichi Isa, Kenji Nakahama, Kyoichi Okishio, Takayuki Shiroyama, Hidekazu Suzuki, Takako Inoue, Motohiro Tamiya, Tomonori Hirashima, Fumio Imamura, Shinji Atagi

ANTICANCER RESEARCH　Vol. 37　No. 10　p. 5857-5862　2017/10　Research paper (scientific journal)

The Association Between Chemotherapy Immediately Before Nivolumab and Outcomes Thereafter

Kenji Nakahama, Shun-Ichi Isa, Akihiro Tamiya, Yoshihiko Taniguchi, Takayuki Shiroyama, Hidekazu Suzuki, Takako Inoue, Motohiro Tamiya, Tomonori Hirashima, Fumio Imamura, Shinji Atagi

ANTICANCER RESEARCH　Vol. 37　No. 10　p. 5885-5891　2017/10　Research paper (scientific journal)

Carboplatin plus weekly nanoparticle albumin-bound paclitaxel in elderly patients with previously untreated advanced squamous non-small-cell lung cancer selected based on Mini Nutritional Assessment short-form scores: a multicenter phase 2 study

Takayuki Shiroyama, Motohiro Tamiya, Seigo Minami, So Takata, Kentaro Masuhiro, Yu Futami-Nishijima, Takeshi Uenami, Masahide Mori, Taro Koba, Takanori Matsuki, Takayuki Takimoto, Hidekazu Suzuki, Norio Okamoto, Kiyoshi Komuta, Tomonori Hirashima, Atsushi Kumanogoh, Takashi Kijima

CANCER CHEMOTHERAPY AND PHARMACOLOGY　Vol. 80　No. 3　p. 461-467　2017/09　Research paper (scientific journal)

Efficacy of nanoparticle albumin-bound paclitaxel regimens for relapsed small cell lung cancer A retrospective analysis

Yujiro Naito, Akihiro Tamiya, Motohiro Tamiya, Yohei Kimura, Masanari Hamaguchi, Nobuhiko Saijo, Masaki Kanazu, Sayoko Tokura, Takayuki Shiroyama, Naoko Morisita, Naoki Omachi, Hidekazu Suzuki, Norio Okamoto, Kyoichi Okishio, Tomonori Hirashima, Shinji Atagi

MEDICINE　Vol. 96　No. 35　2017/09　Research paper (scientific journal)

Correlation of Radiation Pneumonitis History Before Nivolumab with Onset of Interstitial Lung Disease and Progression-free Survival of Patients with Pre-treated Advanced Non-small Cell Lung Cancer

Akihiro Tamiya, Motohiro Tamiya, Kenji Nakahama, Yoshihiko Taniguchi, Takayuki Shiroyama, Shun-Ichi Isa, Takako Inoue, Kyoichi Okishio, Kazumi Nishino, Toru Kumagai, Hidekazu Suzuki, Tomonori Hirashima, Fumio Imamura, Shinji Atagi

ANTICANCER RESEARCH　Vol. 37　No. 9　p. 5199-5205　2017/09　Research paper (scientific journal)

Mandatory dexamethasone strictly monitored by pharmacists reduces the severity of pemetrexed-induced skin rash

Naoko Usui, Yoko Kondo, Noriko Ryota, Hidekazu Suzuki, Norio Okamoto, Masumi Sando, Eriko Tani, Masanari Hamaguchi, Ayako Tanaka, Motohiro Tamiya, Takayuki Shiroyama, Naoko Morishita, Emiko Tanaka, Tomonori Hirashima

EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE　Vol. 24　No. 5　p. 283-285　2017/09　Research paper (scientific journal)

Cerebrospinal Fluid Penetration Rate and Efficacy of Afatinib in Patients with EGFR Mutation-positive Non-small Cell Lung Cancer with Leptomeningeal Carcinomatosis: A Multicenter Prospective Study

Akihiro Tamiya, Motohiro Tamiya, Takashi Nishihara, Takayuki Shiroyama, Keiko Nakao, Taisuke Tsuji, Naoko Takeuchi, Shun-Ichi Isa, Naoki Omachi, Norio Okamoto, Hidekazu Suzuki, Kyoichi Okishio, Ayano Iwazaki, Kimie Imai, Tomonori Hirashima, Shinji Atagi

ANTICANCER RESEARCH　Vol. 37　No. 8　p. 4177-4182　2017/08　Research paper (scientific journal)

Successful retreatment with osimertinib after osimertinib-induced acute pulmonary embolism in a patient with lung adenocarcinoma: A case report.

Takayuki Shiroyama, Manabu Hayama, Shingo Satoh, Shingo Nasu, Ayako Tanaka, Satomu Morita, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Tomonori Hirashima

Respiratory medicine case reports　Vol. 20　p. 25-27　2017

未治療EGFR変異陽性非扁平非小細胞肺癌に対するCDDP/PEM/Bev/Erlotinibの第1相試験

田宮 基裕, 田宮 朗裕, 白山 敬之, 武岡 佐和, 内藤 祐二朗, 大町 直樹, 木村 洋平, 森下 直子, 鈴木 秀和, 岡本 紀雄, 沖塩 協一, 川口 知哉, 安宅 信二, 平島 智徳

肺癌　Vol. 56　No. 6　p. 700-700　2016/11

Vascular Endothelial Growth Factor in Plasma and Pleural Effusion Is a Biomarker for Outcome After Bevacizumab plus Carboplatin-Paclitaxel Treatment for Non-small Cell Lung Cancer with Malignant Pleural Effusion

Motohiro Tamiya, Akihiro Tamiya, Tomomi Yasue, Keiko Nakao, Naoki Omachi, Takayuki Shiroyama, Eriko Tani, Masanari Hamaguchi, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kyoichi Okishio, Tomoya Kawaguchi, Shinji Atagi, Tomonori Hirashima

ANTICANCER RESEARCH　Vol. 36　No. 6　p. 2939-2944　2016/06　Research paper (scientific journal)

A heterochronic genetic change from an EGFR mutation to an ALK rearrangement in a patient with lung adenocarcinoma: a case report

Takayuki Shiroyama, Motohiro Tamiya, Manabu Hayama, Takashi Nishihara, Takuji Nishida, Ayako Tanaka, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kunimitsu Kawahara, Tomonori Hirashima

JOURNAL OF THORACIC DISEASE　Vol. 8　No. 5　p. E345-E348　2016/05　Research paper (scientific journal)

Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study

Manabu Hayama, Norio Okamoto, Hidekazu Suzuki, Motohiro Tamiya, Takayuki Shiroyama, Ayako Tanaka, Takuji Nishida, Takashi Nishihara, Nobuko Uehara, Naoko Morishita, Kunimitsu Kawahara, Tomonori Hirashima

BMC PULMONARY MEDICINE　Vol. 16　No. 1　2016/05　Research paper (scientific journal)

Chemotherapy for patients with advanced lung cancer receiving long-term oxygen therapy

Manabu Hayama, Hidekazu Suzuki, Takayuki Shiroyama, Motohiro Tamiya, Norio Okamoto, Ayako Tanaka, Naoko Morishita, Takuji Nishida, Takashi Nishihara, Tomonori Hirashima

JOURNAL OF THORACIC DISEASE　Vol. 8　No. 1　p. 116-123　2016/01　Research paper (scientific journal)

Effective Management of Persistent Pneumothorax Using a Thopaz (R) Digital Drainage System Combined with an Endobronchial Watanabe Spigot

Takayuki Shiroyama, Norio Okamoto, Motohiro Tamiya, Masanari Hamaguchi, Ayako Tanaka, Takuji Nishida, Manabu Hayama, Takashi Nishihara, Naoko Morishita, Hidekazu Suzuki, Tomonori Hirashima

INTERNAL MEDICINE　Vol. 55　No. 6　p. 663-665　2016　Research paper (scientific journal)

Endoscopic Bronchial Occlusion with Silicon Spigots for the Treatment of an Alveolar-pleural Fistula during Anti-tuberculosis Therapy for Tuberculous Empyema

Takashi Nishihara, Manabu Hayama, Norio Okamoto, Ayako Tanaka, Takuji Nishida, Takayuki Shiroyama, Motohiro Tamiya, Naoko Morishita, Hidekazu Suzuki, Hiroto Matsuoka, Tomonori Hirashima

INTERNAL MEDICINE　Vol. 55　No. 15　p. 2055-2059　2016　Research paper (scientific journal)

Endoscopic bronchial occlusion with silicone spigots under virtual bronchoscopic navigation

Manabu Hayama, Shingo Sato, Takayuki Shiroyama, Takuji Nishida, Takashi Nishihara, Norio Okamoto

Respirology Case Reports　Vol. 4　No. 4　2016　Research paper (scientific journal)

薬剤師外来におけるアファチニブの副作用マネジメント

中野 寛之, 口分田 章典, 木村 貴, 碓氷 尚子, 植田 有希, 志村 和子, 田中 恵美子, 田宮 基裕, 白山 敬之, 西田 拓司, 葉山 学, 田中 彩子, 西原 昴, 森下 直子, 鈴木 秀和, 岡本 紀雄, 平島 智徳, 山東 真寿美

肺癌　Vol. 55　No. 4　p. 312-312　2015/08

Retrospective analysis of the afatinib clinical pathway during the 28-day introductory period - The Japanese style of collaborative drug therapy management (J-CDTM)

Kaori Iwata, Noriko Ryota, Ami Hikita, Masumi Sando, Hidekazu Suzuki, Motohiro Tamiya, Yuichiro Azuma, Eriko Tani, Masanari Hamaguchi, Ayako Tanaka, Takayuki Shiroyama, Naoko Morishita, Norio Okamoto, Sumiko Futagami, Tomonori Hirashima

Japanese Journal of Cancer and Chemotherapy　Vol. 42　No. 8　p. 967-972　2015/08/01　Research paper (scientific journal)

胸部悪性腫瘍患者におけるシスプラチン(CDDP)後発品の安全性の評価

植田 有希, 金銅 葉子, 鈴木 秀和, 岡本 紀雄, 森下 直子, 田宮 基裕, 白山 敬之, 口分田 章典, 碓氷 尚子, 中野 寛之, 山東 真寿美, 田中 恵美子, 平島 智徳

癌と化学療法　Vol. 42　No. 7　p. 827-832　2015/07

Evaluation of Bone Metastasis Using Serial Measurements of Serum N-Telopeptides of Type I Collagen in Patients with Lung Cancer: A Prospective Study

Motohiro Tamiya, Shinya Tokunaga, Hideaki Okada, Hidekazu Suzuki, Shinji Sasada, Norio Okamoto, Naoko Morishita, Takayuki Shiroyama, Tomoyuki Otsuka, Natsuko Miyamoto, Koichi Taira, Haruko Daga, Koji Takeda, Tomonori Hirashima

ANTICANCER RESEARCH　Vol. 35　No. 7　p. 3987-3993　2015/07　Research paper (scientific journal)

Evaluation of the safety of a generic formulation of cisplatin in patients with thoracic malignancies

Yuki Ueda, Yoko Kondo, Hidekazu Suzuki, Norio Okamoto, Naoko Morishita, Motohiro Tamiya, Takayuki Shiroyama, Akinori Kumode, Naoko Usui, Hiroyuki Nakano, Masumi Sando, Emiko Tanaka, Tomonori Hirashima

Japanese Journal of Cancer and Chemotherapy　Vol. 42　No. 7　p. 827-832　2015/07/01　Research paper (scientific journal)

Relationship between progression-free survival and overall survival in patients with advanced non-small cell lung cancer treated with anticancer agents after first-line treatment failure

Hidekazu Suzuki, Tomonori Hirashima, Norio Okamoto, Tadahiro Yamadori, Motohiro Tamiya, Naoko Morishita, Takayuki Shiroyama, Sawa Takeoka, Akio Osa, Yuichiro Azuma, Ichiro Kawase

ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY　Vol. 11　No. 2　p. 121-128　2015/06　Research paper (scientific journal)

Phase II trial of carboplatin, S-1, and gefitinib as first-line triplet chemotherapy for advanced non-small cell lung cancer patients with activating epidermal growth factor receptor mutations

Akihiro Tamiya, Motohiro Tamiya, Takayuki Shiroyama, Nobuhiko Saijo, Takeshi Nakatani, Shojiro Minomo, Taisuke Tsuji, Naoko Takeuchi, Naoki Omachi, Kanako Kurata, Hidekazu. Suzuki, Norio Okamoto, Kyoichi Okishio, Tomonori Hirashima, Shinji Atagi

MEDICAL ONCOLOGY　Vol. 32　No. 3　2015/03　Research paper (scientific journal)

The Alternatively Spliced Actinin-4 Variant as a Prognostic Marker for Metastasis in Small-cell Lung Cancer

Norio Okamoto, Hidekazu Suzuki, Kunimitsu Kawahara, Kazufumi Honda, Nami Miura, Tomonori Hirashima, Motohiro Tamiya, Naoko Morishita, Takayuki Shiroyama, Ayako Tanaka, Eriko Tani, Masanari Hamaguchi, Masashi Kitani, Tesshi Yamada, Ichiro Kawase

ANTICANCER RESEARCH　Vol. 35　No. 3　p. 1663-1667　2015/03　Research paper (scientific journal)

A Rare Case of Pleomorphic Carcinoma of the Lung Harboring an Anaplastic Lymphoma Kinase (ALK) Rearrangement

Takayuki Shiroyama, Ayako Tanaka, Motohiro Tamiya, Masanari Hamaguchi, Akio Osa, Sawa Takeoka, Eriko Tani, Yuichiro Azuma, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kenji Kimura, Yoshihisa Kadota, Kunimitsu Kawahara, Tomonori Hirashima, Ichiro Kawase

INTERNAL MEDICINE　Vol. 54　No. 21　p. 2741-2743　2015　Research paper (scientific journal)

Nanoparticle Albumin-bound Paclitaxel plus Carboplatin Therapy for Small Cell Lung Cancer Combined with Squamous Cell Carcinoma and Interstitial Lung Disease

Yuichiro Azuma, Motohiro Tamiya, Takayuki Shiroyama, Akio Osa, Sawa Takeoka, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Tomonori Hirashima, Ichiro Kawase

INTERNAL MEDICINE　Vol. 54　No. 22　p. 2911-2913　2015　Research paper (scientific journal)

Denosumab for bone metastasis of thoracic tumors-preparation of a practice manual and evaluation of its effectiveness

Yoko Kondo, Motohiro Tamiya, Tomonori Hirashima, Noriko Ryota, Masumi Sando, Kaori Iwata, Norio Okamoto, Hidekazu Suzuki, Naoko Morishita, Takayuki Shiroyama, Sawa Takeoka, Akio Osa, Yuichiro Azuma, Tsunemi Tsuboi, Akihiro Yamato, Kazuko Shimura, Ichiro Kawase

Japanese Journal of Cancer and Chemotherapy　Vol. 41　No. 11　p. 1391-1395　2014/11/01　Research paper (scientific journal)

ペメトレキセドによる発疹に対するデキサメタゾンの予防効果の評価

碓氷 尚子, 平島 智徳, 良田 紀子, 中野 寛之, 山東 真寿美, 志村 和子, 谷 恵利子, 東 祐一郎, 濱口 眞成, 田中 彩子, 白山 敬之, 田宮 基裕, 森下 直子, 鈴木 秀和, 岡本 紀雄, 川瀬 一郎

肺癌　Vol. 54　No. 5　p. 573-573　2014/10

未治療進行EGFR遺伝子変異陽性肺癌に対するエスワン+カルボプラチン+ゲフィチニブ第二相試験

辻 泰佑, 田宮 朗裕, 田宮 基裕, 仲谷 健史, 西條 伸彦, 倉田 香菜子, 白山 敬之, 蓑毛 祥次郎, 森下 直子, 大町 直樹, 浅見 和弘, 岡本 紀雄, 鈴木 秀和, 沖塩 協一, 川口 知哉, 平島 智徳, 安宅 信二

肺癌　Vol. 54　No. 5　p. 320-320　2014/10

Opioid switch from low dose of oral oxycodone to transdermal fentanyl matrix patch for patients with stable thoracic malignancy-related pain

Seigo Minami, Takashi Kijima, Takeshi Nakatani, Suguru Yamamoto, Yoshitaka Ogata, Haruhiko Hirata, Takayuki Shiroyama, Taro Koba, Kiyoshi Komuta

BMC PALLIATIVE CARE　Vol. 13　2014/10　Research paper (scientific journal)

Comparison of the clinical courses and chemotherapy outcomes in metastatic colorectal cancer patients with and without active Mycobacterium tuberculosis or Mycobacterium kansasii infection: a retrospective study

Tomonori Hirashima, Takayuki Nagai, Hironori Shigeoka, Yoshitaka Tamura, Hiroko Yoshida, Kunimitsu Kawahara, Yoko Kondoh, Kenichi Sakai, Shoji Hashimoto, Makoto Fujishima, Takayuki Shiroyama, Motohiro Tamiya, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Ichiro Kawase

BMC CANCER　Vol. 14　2014/10　Research paper (scientific journal)

Important factors for achieving survival of five years or more in non-small cell lung cancer patients with distant metastasis

Tomonori Hirashima, Hidekazu Suzuki, Norio Okamoto, Naoko Morishita, Tadahiro Yamadori, Motohiro Tamiya, Takayuki Shiroyama, Kanako Kurata, Ichiro Kawase

ONCOLOGY LETTERS　Vol. 8　No. 1　p. 327-334　2014/07　Research paper (scientific journal)

Stratification of Malignant Pleural Mesothelioma Prognosis Using Recursive Partitioning Analysis

Hidekazu Suzuki, Kazuhiro Asami, Tomonori Hirashima, Norio Okamoto, Tadahiro Yamadori, Motohiro Tamiya, Naoko Morishita, Takayuki Shiroyama, Sawa Takeoka, Akio Osa, Yuichiro Azuma, Kyoichi Okishio, Tomoya Kawaguchi, Shinji Atagi, Ichiro Kawase

LUNG　Vol. 192　No. 1　p. 191-195　2014/02　Research paper (scientific journal)

胸水貯留非扁平上皮非小細胞肺癌に対するCarboplatin+paclitaxel+bevacizumab第二相試験

園延 尚子, 田宮 基裕, 田宮 朗裕, 大町 直樹, 浅見 和弘, 蓑毛 祥次郎, 中尾 桂子, 直木 陽子, 西條 伸彦, 白山 敬之, 山鳥 忠宏, 森下 直子, 金津 正樹, 鈴木 秀和, 岡本 紀雄, 沖塩 協一, 川口 知哉, 平島 智徳, 安宅 信二, 川瀬 一郎

肺癌　Vol. 53　No. 5　p. 449-449　2013/10

Phase2 study of bevacizumab with carboplatin-paclitaxel for non-small cell lung cancer with malignant pleural effusion

Motohiro Tamiya, Akihiro Tamiya, Tadahiro Yamadori, Keiko Nakao, Kazuhiro Asami, Tomomi Yasue, Tomoyuki Otsuka, Takayuki Shiroyama, Naoko Morishita, Hidekazu Suzuki, Norio Okamoto, Kyoichi Okishio, Tomoya Kawaguchi, Shinji Atagi, Ichiro Kawase, Tomonori Hirashima

MEDICAL ONCOLOGY　Vol. 30　No. 3　2013/09　Research paper (scientific journal)

Diagnostic yield of combined bronchoscopy and endobronchial ultrasonography, under LungPoint guidance for small peripheral pulmonary lesions

Motohiro Tamiya, Norio Okamoto, Shinji Sasada, Takayuki Shiroyama, Naoko Morishita, Hidekazu Suzuki, Emi Yoshida, Tomonori Hirashima, Kunimitu Kawahara, Ichiro Kawase

RESPIROLOGY　Vol. 18　No. 5　p. 834-839　2013/07　Research paper (scientific journal)

Carboplatin plus paclitaxel in combination with bevacizumab for the treatment of adenocarcinoma with interstitial lung diseases.

Hidekazu Suzuki, Tomonori Hirashima, Masashi Kobayashi, Norio Okamoto, Yuka Matsuura, Motohiro Tamiya, Naoko Morishita, Kohei Okafuji, Takayuki Shiroyama, Osamu Morimura, Satomu Morita, Ichiro Kawase

Molecular and clinical oncology　Vol. 1　No. 3　p. 480-482　2013/05

癌性胸膜炎症例に対するOK-432による胸膜癒着療法の有用性および安全性の検討

大塚 倫之, 平島 智徳, 岡本 紀雄, 鈴木 秀和, 山鳥 忠宏, 森下 直子, 田宮 基裕, 白山 敬之, 北井 香菜子, 川瀬 一郎

日本呼吸器学会誌　Vol. 2　No. 増刊　p. 296-296　2013/03

The relationship between tyrosine kinase inhibitor therapy and overall survival in patients with non-small cell lung cancer carrying EGFR mutations

Hidekazu Suzuki, Tomonori Hirashima, Norio Okamoto, Tadahiro Yamadori, Motohiro Tamiya, Naoko Morishita, Takayuki Shiroyama, Tomoyuki Otsuka, Kanako Kitai, Ichiro Kawase

CHINESE JOURNAL OF CANCER　Vol. 32　No. 3　p. 136-140　2013/03　Research paper (scientific journal)

Clinical Significance of the Serum Crosslinked N-Telopeptide of Type I Collagen as a Prognostic Marker for Non-Small-Cell Lung Cancer

Motohiro Tamiya, Masashi Kobayashi, Osamu Morimura, Tomomi Yasue, Takashi Nakasuji, Morita Satomu, Okafuji Kohei, Shiroyama Takayuki, Naoko Morishita, Hidekazu Suzuki, Shinji Sasada, Norio Okamoto, Tomonori Hirashima, Ichiro Kawase

CLINICAL LUNG CANCER　Vol. 14　No. 1　p. 50-54　2013/01　Research paper (scientific journal)

Impact of pneumonia on hyperactive delirium in end-stage lung cancer patients

Hidekazu Suzuki, Tomonori Hirashima, Masashi Kobayashi, Norio Okamoto, Yuka Matsuura, Motohiro Tamiya, Naoko Morishita, Kohei Okafuji, Takayuki Shiroyama, Osamu Morimura, Satomu Morita, Ichiro Kawase

SUPPORTIVE CARE IN CANCER　Vol. 21　No. 1　p. 281-285　2013/01　Research paper (scientific journal)

Randomized Phase II trial of paclitaxel and carboplatin followed by gemcitabine switch-maintenance therapy versus gemcitabine and carboplatin followed by gemcitabine continuation-maintenance therapy in previously untreated advanced non-small cell lung cancer

Seigo Minami, Takashi Kijima, Takayuki Shiroyama, Kohei Okafuji, Tomonori Hirashima, Junji Uchida, Fumio Imamura, Tadashi Osaki, Takeshi Nakatani, Yoshitaka Ogata, Suguru Yamamoto, Yoshinobu Namba, Tomoyuki Otsuka, Isao Tachibana, Kiyoshi Komuta, Ichiro Kawase

BMC Research Notes　Vol. 6　No. 1　2013　Research paper (scientific journal)

Usefulness of high suction pressure for sufficient tissue collection during endobronchial ultrasound guided transbronchial needle aspiration.

Takayuki Shiroyama, Norio Okamoto, Hidekazu Suzuki, Motohiro Tamiya, Tadahiro Yamadori, Naoko Morishita, Tomoyuki Otsuka, Satomu Morita, Kanako Kurata, Akira Okimura, Kunimitsu Kawahara, Shinji Sasada, Tomonori Hirashima, Ichiro Kawase

PloS one　Vol. 8　No. 12　2013　Research paper (scientific journal)

Phase II tailored S-1 regimen study of first-line chemotherapy in elderly patients with advanced and recurrent non-small cell lung cancer

Takayuki Shiroyama, Takashi Kijima, Kiyoshi Komuta, Suguru Yamamoto, Seigo Minami, Yoshitaka Ogata, Kouhei Okafuji, Fumio Imamura, Tomonori Hirashima, Isao Tachibana, Ichiro Kawase, Atsushi Kumanogoh

CANCER CHEMOTHERAPY AND PHARMACOLOGY　Vol. 70　No. 6　p. 783-789　2012/12　Research paper (scientific journal)

Efficacy of Carboplatin and Paclitaxel with Bevacizumab as Salvage Chemotherapy for Non-small Cell Lung Cancer after Failure of Platinum-doublet Chemotherapy

Motohiro Tamiya, Akihiro Tamiya, Keiko Nakao, Kazuhiro Asami, Kyoichi Okishio, Morita Satomu, Takayuki Shiroyama, Naoko Morishita, Hidekazu Suzuki, Shinji Sasada, Norio Okamoto, Kyoichi Okishio, Tomoya Kawaguchi, Masashi Kobayashi, Shinji Atagi, Tomonori Hirashima, Ichiro Kawase

ANTICANCER RESEARCH　Vol. 32　No. 8　p. 3553-3557　2012/08　Research paper (scientific journal)

Prognostic Factors in Malignant Pleural Mesothelioma: A Retrospective Study

Hidekazu Suzuki, Tomonori Hirashima, Masashi Kobayashi, Norio Okamoto, Yuka Matsuura, Motohiro Tamiya, Naoko Morishita, Kohei Okafuji, Takayuki Shiroyama, Osamu Morimura, Satomu Morita, Ichiro Kawase

INTERNAL MEDICINE　Vol. 51　No. 7　p. 707-710　2012　Research paper (scientific journal)

Phase II study of S-1 monotherapy in platinum-refractory, advanced non-small cell lung cancer

Takayuki Shiroyama, Kiyoshi Komuta, Fumio Imamura, Tomonori Hirashima, Takashi Kijima, Isao Tachibana, Ichiro Kawase

LUNG CANCER　Vol. 74　No. 1　p. 85-88　2011/10　Research paper (scientific journal)

Outpatient chemotherapy and clinical pathway for advanced non-small-cell lung cancer

Kiyoshi Komuta, Takeshi Nakatani, Kohei Okafuji, Takayuki Shiroyama, Seigo Minami, Yoshitaka Ogata, Chikako Kobayashi, Suguru Yamamoto

Japanese Journal of Lung Cancer　Vol. 51　No. 2　p. 119-121　2011/04　Research paper (international conference proceedings)

A case of small bowel metastasis from lung adenocarcinoma diagnosed by double-balloon enteroscopy

Takayuki Shiroyama, Yoshitaka Ogata, Seigo Minami, Kohei Okafuji, Masahiko Tsujimoto, Kiyoshi Komuta

Japanese Journal of Lung Cancer　Vol. 50　No. 3　p. 303-307　2010/06　Research paper (scientific journal)