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Kanai Yoshikatsu

金井 好克

Graduate School of Medicine Division of Medicine, Professor

keyword Molecular Physiology,Molecular Pathophysiology,Molecular Pharmacology

Education

  • - 1988, The University of Tokyo
  • - 1988, The University of Tokyo, Graduate School, Division of Medical Sciences
  • - 1984, Gunma University, Faculty of Medicine, School of Medicine
  • - 1984, Gunma University, Faculty of Medicine

Research History

  • 2007/10 - Present, 大阪大学医学系研究科・教授
  • 2004/04 - 2007/09, Kyorin University, Faculty of Medicine
  • 2001/04 - 2004/03, Kyorin University, Faculty of Medicine
  • 1998/10 - 2001/09, 科学技術振興事業団個人研究推進事業 さきがけ研究21「素過程と連携」領域研究者(兼務)
  • 1996/04 - 2001/03, Kyorin University, Faculty of Medicine
  • 1993/12 - 1996/03, Kyorin University, Faculty of Medicine
  • 1991/04 - 1993/11, 米国Harvard University博士研究員 (Brigham and Women's Hospital, Renal Division)
  • 1988/04 - 1993/11, 東京大学助手(医学部医学科衛生学)

Research Areas

  • Life sciences, Pathobiochemistry
  • Life sciences, Pharmacology
  • Life sciences, Clinical pharmacy
  • Life sciences, Physiology
  • Life sciences, Pathobiochemistry
  • Life sciences, Pharmacology
  • Life sciences, Clinical pharmacy
  • Life sciences, Physiology

Professional Memberships

  • THE JAPANESE CANCER ASSOCIATION
  • 米国腎臓学会
  • THE JAPAN DIABETES SOCIETY
  • THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS
  • 米国薬理学会
  • がん分子標的治療研究会
  • 米国細胞生物学会
  • 米国神経科学会
  • 米国生化学分子生物学会
  • 日本腎臓学会
  • 日本毒性学会(評議員)
  • 日本蛋白質科学会
  • 日本細胞生物学会
  • 日本分子生物学会
  • THE JAPANESE BIOCHEMICAL SOCIETY
  • 日本薬理学会(評議員)

Papers

  • Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer, Masahiro Sugiura,Hiroaki Sato,Atsushi Okabe,Masaki Fukuyo,Yasunobu Mano,Ken-ichi Shinohara,Bahityar Rahmutulla,Kosuke Higuchi,Maihulan Maimaiti,Manato Kanesaka,Yusuke Imamura,Tomomi Furihata,Shinichi Sakamoto,Akira Komiya,Naohiko Anzai,Yoshikatsu Kanai,Jun Luo,Tomohiko Ichikawa,Atsushi Kaneda, Translational Oncology, Elsevier BV, Vol. 14, No. 1, p. 100915-100915, 2021/01
  • Individual dosimetry system for targeted alpha therapy based on PHITS coupled with microdosimetric kinetic model, Tatsuhiko Sato,Takuya Furuta,Yuwei Liu,Sadahiro Naka,Shushi Nagamori,Yoshikatsu Kanai,Tadashi Watabe, EJNMMI Physics, Springer Science and Business Media LLC, Vol. 8, No. 1, 2021/01
  • α‐Emitting cancer therapy using 211 At‐AAMT targeting LAT1, Kazuko Kaneda‐Nakashima,ZiJian Zhang,Yoshiyuki Manabe,Atsushi Shimoyama,Kazuya Kabayama,Tadashi Watabe,Yoshikatsu Kanai,Kazuhiro Ooe,Atsushi Toyoshima,Yoshifumi Shirakami,Takashi Yoshimura,Mitsuhiro Fukuda,Jun Hatazawa,Takashi Nakano,Koichi Fukase,Atsushi Shinohara, Cancer Science, Wiley, 2020/12/05
  • Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor, Hiroki Okanishi,Ryuichi Ohgaki,Suguru Okuda,Hitoshi Endou,Yoshikatsu Kanai, Cancer Science, Wiley, 2020/12/02
  • Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes, Chunhuan Jin,Ling Wei,Ryuichi Ohgaki,Hideyuki Tominaga,Minhui Xu,Suguru Okuda,Hiroki Okanishi,Yasuharu Kawamoto,Xin He,Shushi Nagamori,Yoshikatsu Kanai, Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology & Experimental Therapeutics (ASPET), Vol. 375, No. 3, p. 451-462, 2020/12
  • Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation, Lili Quan,Ryuichi Ohgaki,Saori Hara,Suguru Okuda,Ling Wei,Hiroki Okanishi,Shushi Nagamori,Hitoshi Endou,Yoshikatsu Kanai, Journal of Experimental & Clinical Cancer Research, Springer Science and Business Media LLC, Vol. 39, No. 1, 2020/12
  • Structural changes induced by ligand binding drastically increase the thermostability of the Ser/Thr protein kinase TpkD from Thermus thermophilus HB8, Yusuke Fujino,Takero Miyagawa,Masayuki Torii,Masao Inoue,Yuki Fujii,Hiroki Okanishi,Yoshikatsu Kanai,Ryoji Masui, FEBS Letters, Wiley, 2020/11/28
  • A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy, Keisuke Jimbo,Toshiaki Okuno,Ryuichi Ohgaki,Kou Nishikubo,Yuri Kitamura,Yumiko Sakurai,Lili Quan,Hiromichi Shoji,Yoshikatsu Kanai,Toshiaki Shimizu,Takehiko Yokomizo, PLOS ONE, Public Library of Science (PLoS), Vol. 15, No. 11, p. e0241869-e0241869, 2020/11/09
  • Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application, Gergely Gyimesi,Jonai Pujol-Giménez,Yoshikatsu Kanai,Matthias A. Hediger, Pflügers Archiv - European Journal of Physiology, Springer Science and Business Media LLC, Vol. 472, No. 9, p. 1177-1206, 2020/09
  • Targeted alpha therapy using astatine (211At)-labeled phenylalanine: A preclinical study in glioma bearing mice., Tadashi Watabe,Kazuko Kaneda-Nakashima,Yoshifumi Shirakami,Yuwei Liu,Kazuhiro Ooe,Takahiro Teramoto,Atsushi Toyoshima,Eku Shimosegawa,Takashi Nakano,Yoshikatsu Kanai,Atsushi Shinohara,Jun Hatazawa, Oncotarget, Vol. 11, No. 15, p. 1388-1398, 2020/04/14
  • Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma., Maihulan Maimaiti,Shinichi Sakamoto,Yasutaka Yamada,Masahiro Sugiura,Junryo Rii,Nobuyoshi Takeuchi,Yusuke Imamura,Tomomi Furihata,Keisuke Ando,Kosuke Higuchi,Minhui Xu,Tomokazu Sazuka,Kazuyoshi Nakamura,Atsushi Kaneda,Yoshikatsu Kanai,Natasha Kyprianou,Yuzuru Ikehara,Naohiko Anzai,Tomohiko Ichikawa, Scientific reports, Vol. 10, No. 1, p. 1292-1292, 2020/01/28
  • Evaluation of D-isomer of 18F-FBPA for oncology PET focusing on the differentiation of glioma and inflammation., Nobuto Hirai,Tadashi Watabe,Shushi Nagamori,Pattama Wiriyasermkul,Yoko Tanaka,Victor Romanov,Sadahiro Naka,Yasukazu Kanai,Yuwei Liu,Naoki Tani,Tatsuya Sakai,Mitsuaki Tatsumi,Eku Shimosegawa,Yoshikatsu Kanai,Jun Hatazawa, Asia Oceania journal of nuclear medicine & biology, Vol. 8, No. 2, p. 102-108, 2020
  • THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters., Alexander SPH,Kelly E,Mathie A,Peters JA,Veale EL,Armstrong JF,Faccenda E,Harding SD,Pawson AJ,Sharman JL,Southan C,Davies JA,CGTP Collaborators, Br J Pharmacol., Vol. 176, No. Suppl 1, p. S397-S493, 2019/12
  • LAT1-specific inhibitor is effective against T cell-mediated allergic skin inflammation., Hayashi K,Kaminuma O,Nishimura T,Saeki M,Matsuoka K,Hiroi T,Jutabha P,Iwata Y,Sugiura K,Owada T,Kurasawa K,Okayasu I,Ouchi M,Fujita T,Kanai Y,Endou H,Anzai N, Allergy, 2019/08
  • Cell surface pH imaging using poly(ethylene glycol)-phospholipid: its potential as the core structure of membrane anchored-probes., Vol. 153, No. 6, p. 254-260, 2019/06
  • CYP450s-Activity Relations of Celastrol to Interact with Triptolide Reveal the Reasons of Hepatotoxicity of Tripterygium wilfordii., Jin C,Wu Z,Wang L,Kanai Y,He, Molecules, Vol. 24, No. 11, 2019/06
  • Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc., Lee Y,Wiriyasermkul P,Jin C,Quan L,Ohgaki R,Okuda S,Kusakizako T,Nishizawa T,Oda K,Ishitani R,Yokoyama T,Nakane T,Shirouzu M,Endou H,Nagamori S,Kanai Y,Nureki O, Nat Struct Mol Biol., Vol. 26, No. 6, p. 510-517, 2019/06
  • Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2., Masanao Aoki,Tadashi Watabe,Shushi Nagamori,Sadahiro Naka,Hayato Ikeda,Pornparn Kongpracha,Genki Horitsugi,Yasukazu Kanai,Eku Shimosegawa,Yoshikatsu Kanai,Jun Hatazawa, Annals of nuclear medicine, Vol. 33, No. 6, p. 394-403, 2019/06
  • Role of Amino Acid Transporter Expression as a Prognostic Marker in Patients With Surgically Resected Colorectal Cancer., Ogawa H,Kaira K,Motegi Y,Yokobori T,Takada T,Katoh R,Osone K,Takahashi R,Katayama C,Oyama T,Kanai Y,Yao T,Asao T,Kuwano H,Shirabe K, Anticancer Res., Vol. 39, No. 5, p. 2535-2543, 2019/05
  • An L-type Amino Acid Transporter-1 Specific Imaging Agent: Structure-function Relationships of Radioiodinated Tyrosine Derivatives., Shikano N,Kanai Y,Kawai K,Inatomi J,Kim D.K,Endou H, ASVPI, Vol. 24, p. 23-28, 2019/03
  • Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter., Miyabe J,Ohgaki R,Saito K,Wei L,Quan L,Jin C,Liu X,Okuda S,Nagamori S,Ohki H,Yoshino K,Inohara H,Kanai Y, J Pharmacol Sci., Vol. 139, No. 3, p. 215-222, 2019/03
  • Expression of amino acid transporter (LAT1 and 4F2hc) in pulmonary pleomorphic carcinoma., Kaira K,Kawashima O,Endoh H,Imaizumi K,Goto Y,Kamiyoshihara M,Sugano M,Yamamoto R,Osaki T,Tanaka S,Fujita A,Imai H,Kogure Y,Seki Y,Shimizu K,Mogi A,Shitara Y,Oyama T,Kanai Y,Asao T, Human pathology, Vol. 84, p. 142-149, 2019/02
  • Investigation of novel drug for nuclear medicine targeting to cancer specific amino acid transporter, LAT1, Kaneda Kazuko,Zhang ZiJian,Manabe Yoshiyuki,Shimoyama Atsushi,Kabayama Kazuya,Kanai Yoshikatsu,Fukase Koichi,Shinohara Atsushi, CANCER SCIENCE, Vol. 109, 2018/12
  • Amino acid transporters revisited: New views in health and disease., Kandasamy P,Gyimesi G,Kanai Y,Hediger MA, Trends Biochem Sci., 2018/08
  • Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex., Liang Weng,Yi-Peng Han,Atsushi Enomoto,Yasuyuki Kitaura,Shushi Nagamori,Yoshikatsu Kanai,Naoya Asai,Jian An,Maki Takagishi,Masato Asai,Shinji Mii,Takashi Masuko,Yoshiharu Shimomura,Masahide Takahashi, PLoS biology, Vol. 16, No. 3, 2018/03
  • Relationship between LAT1 expression and resistance to chemotherapy in pancreatic ductal adenocarcinoma, Bolag Altan,Kyoichi Kaira,Akira Watanabe,Norio Kubo,Pinjie Bao,Gantumur Dolgormaa,Erkhem-Ochir Bilguun,Kenichiro Araki,Yoshikatsu Kanai,Takehiko Yokobori,Tetsunari Oyama,Masahiko Nishiyama,Hiroyuki Kuwano,Ken Shirabe, Cancer Chemotherapy and Pharmacology, Springer Verlag, Vol. 81, No. 1, p. 141-153, 2018/01/01
  • Impairment of the carnitine/organic cation transporter 1-ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease, Yasuyuki Shinozaki,Kengo Furuichi,Tadashi Toyama,Shinji Kitajima,Akinori Hara,Yasunori Iwata,Norihiko Sakai,Miho Shimizu,Shuichi Kaneko,Noriyoshi Isozumi,Shushi Nagamori,Yoshikatsu Kanai,Tomoko Sugiura,Yukio Kato,Takashi Wada, KIDNEY INTERNATIONAL, ELSEVIER SCIENCE INC, Vol. 92, No. 6, p. 1356-1369, 2017/12
  • Ratiometric fluorescence imaging of cell surface pH by poly(ethylene glycol)-phospholipid conjugated with fluorescein isothiocyanate, Ryuichi Ohgaki,Yuji Teramura,Daichi Hayashi,Lili Quan,Suguru Okuda,Shushi Nagamori,Madoka Takai,Yoshikatsu Kanai, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 7, No. 1, 2017/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview, Stephen P. H. Alexander,Eamonn Kelly,Neil V. Marrion,John A. Peters,Elena Faccenda,Simon D. Harding,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,O. Peter Buneman,John A. Cidlowski,Arthur Christopoulos,Anthony P. Davenport,Doriano Fabbro,Michael Spedding,Jorg Striessnig,Jamie A. Davies, BRITISH JOURNAL OF PHARMACOLOGY, WILEY, Vol. 174, No. Suppl 1, p. S1-S16, 2017/12
  • Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells, Kayo Ikeda,Makoto Kinoshita,Hisako Kayama,Shushi Nagamori,Pornparn Kongpracha,Eiji Umemoto,Ryu Okumura,Takashi Kurakawa,Mari Murakami,Norihisa Mikami,Yasunori Shintani,Satoko Ueno,Ayatoshi Andou,Morihiro Ito,Hideki Tsumura,Koji Yasutomo,Keiichi Ozono,Seiji Takashima,Shimon Sakaguchi,Yoshikatsu Kanai,Kiyoshi Takeda, CELL REPORTS, CELL PRESS, Vol. 21, No. 7, p. 1824-1838, 2017/11
  • JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells, Dae Woo Choi,Do Kyung Kim,Yoshikatsu Kanai,Michael F. Wempe,Hitoshi Endou,Jong-Keun Kim, KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, Vol. 21, No. 6, p. 599-607, 2017/11
  • Clinical Significance and Phenotype of MTA1 Expression in Esophageal Squamous Cell Carcinoma, Hiroaki Honjo,Yasushi Toh,Makoto Sohda,Shigemasa Suzuki,Kyoichi Kaira,Yoshikatsu Kanai,Shushi Nagamori,Tetsunari Oyama,Takehiko Yokobori,Tatsuya Miyazaki,Hiroyuki Kuwano, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 37, No. 8, p. 4147-4155, 2017/08
  • Essential roles of L-type amino acid transporter 1 in syncytiotrophoblast development by presenting fusogenic 4F2hc, Ryuichi Ohgaki,Takahiro Ohmori,Saori Hara,Saya Nakagomi,Masami Kanai-Azuma,Kazuko Kaneda-Nakashima,Suguru Okuda,Shushi Nagamori,Yoshikatsu Kanai, Molecular and Cellular Biology, Vol. 37, No. 11, 2017/06/01
  • Ultrastructural immunohistochemical study of L-type amino acid transporter 1-4F2 heavy chain in tumor microvasculatures of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced rat bladder carcinoma, Eisuke Kume,Tomoko Mutou,Norio Kansaku,Hitoyuki Takahashi,Michael F. Wempe,Masahiro Ikegami,Yoshikatsu Kanai,Hitoshi Endou,Shin Wakui, MICROSCOPY, OXFORD UNIV PRESS, Vol. 66, No. 3, p. 198-203, 2017/06
  • Utilization of Liver Microsomes to Estimate Hepatic Intrinsic Clearance of Monoamine Oxidase Substrate Drugs in Humans, Yusuke Masuo,Shushi Nagamori,Aoi Hasegawa,Kazuki Hayashi,Noriyoshi Isozumi,Noritaka Nakamichi,Yoshikatsu Kanai,Yukio Kato, PHARMACEUTICAL RESEARCH, SPRINGER/PLENUM PUBLISHERS, Vol. 34, No. 6, p. 1233-1243, 2017/06
  • Increased Dynamics of Tricarboxylic Acid Cycle and Glutamate Synthesis in Obese Adipose Tissue IN VIVO METABOLIC TURNOVER ANALYSIS, Hirofumi Nagao,Hitoshi Nishizawa,Takeshi Bamba,Yasumune Nakayama,Noriyoshi Isozumi,Shushi Nagamori,Yoshikatsu Kanai,Yoshimitsu Tanaka,Shunbun Kita,Shiro Fukuda,Tohru Funahashi,Norikazu Maeda,Eiichiro Fukusaki,Iichiro Shimomura, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 292, No. 11, p. 4469-4483, 2017/03
  • Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer, Kenji Ohshima,Satoshi Nojima,Shinichiro Tahara,Masako Kurashige,Yumiko Hori,Kohei Hagiwara,Daisuke Okuzaki,Shinya Oki,Naoki Wada,Jun-ichiro Ikeda,Yoshikatsu Kanai,Eiichi Morii, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 7, 2017/03
  • F-18-FBPA as a tumor-specific probe of L-type amino acid transporter 1 (LAT1): a comparison study with F-18-FDG and C-11-Methionine PET, Tadashi Watabe,Hayato Ikeda,Shushi Nagamori,Pattama Wiriyasermkul,Yoko Tanaka,Sadahiro Naka,Yasukazu Kanai,Kohei Hagiwara,Masanao Aoki,Eku Shimosegawa,Yoshikatsu Kanai,Jun Hatazawa, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, SPRINGER, Vol. 44, No. 2, p. 321-331, 2017/02
  • Prognostic Significance of the Expression of CD98 (4F2hc) in Gastric Cancer, Taisuke Satoh,Kyoichi Kaira,Kengo Takahashi,Norihumi Takahashi,Yoshikatsu Kanai,Takayuki Asao,Jun Horiguchi,Tetsunari Oyama, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 37, No. 2, p. 631-636, 2017/02
  • Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1), Pornparn Kongpracha,Shushi Nagamori,Pattama Wiriyasermkul,Yoko Tanaka,Kazuko Kaneda,Suguru Okuda,Ryuichi Ohgaki,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 133, No. 2, p. 96-102, 2017/02
  • Prognostic impact of LAT1 and CD98 expression in cutaneous angiosarcoma, A. Shimizu,K. Kaira,Y. Okubo,D. Utsumi,M. Yasuda,H. Tominaga,N. Oriuchi,Y. Kanai,K. Takahashi,O. Ishikawa, NEOPLASMA, AEPRESS SRO, Vol. 64, No. 2, p. 283-288, 2017
  • Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder, Dora C. Tarlungeanu,Elena Deliu,Christoph P. Dotter,Majdi Kara,Philipp Christoph Janiesch,Mariafrancesca Scalise,Michele Galluccio,Mateja Tesulov,Emanuela Morelli,Fatma Mujgan Sonmez,Kaya Bilguvar,Ryuichi Ohgaki,Yoshikatsu Kanai,Anide Johansen,Seham Esharif,Tawfeg Ben-Omran,Meral Topcu,Avner Schlessinger,Cesare Indiveri,Kent E. Duncan,Ahmet Okay Caglayan,Murat Gunel,Joseph G. Gleeson,Gaia Novarino, CELL, CELL PRESS, Vol. 167, No. 6, p. 1481-+, 2016/12
  • Core-fucosylation plays a pivotal role in hepatitis B pseudo virus infection: a possible implication for HBV glycotherapy, Shinji Takamatsu,Mayuka Shimomura,Yoshihiro Kamada,Haruka Maeda,Tomoaki Sobajima,Hayato Hikita,Masumi Iijima,Yuta Okamoto,Ryo Misaki,Kazuhito Fujiyama,Shushi Nagamori,Yoshikatsu Kanai,Tetsuo Takehara,Keiji Ueda,Shun'ichi Kuroda,Eiji Miyoshi, GLYCOBIOLOGY, OXFORD UNIV PRESS INC, Vol. 26, No. 11, p. 1180-1189, 2016/11
  • Efficacy of system l amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma, Yasuhiro Ohshima,Kyoichi Kaira,Aiko Yamaguchi,Noboru Oriuchi,Hideyuki Tominaga,Shushi Nagamori,Yoshikatsu Kanai,Takehiko Yokobori,Tatsuya Miyazaki,Takayuki Asao,Yoshito Tsushima,Hiroyuki Kuwano,Noriko S. Ishioka, Cancer Science, Blackwell Publishing Ltd, Vol. 107, No. 10, p. 1499-1505, 2016/10/01
  • Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features, Ryuichi Ohgaki,Ling Wei,Kazunori Yamada,Taiki Hara,Chiaki Kuriyama,Suguru Okuda,Kiichiro Ueta,Masaharu Shiotani,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 358, No. 1, p. 94-102, 2016/07
  • Up-Regulation of LAT1 during Antiandrogen Therapy Contributes to Progression in Prostate Cancer Cells, Minhui Xu,Shinichi Sakamoto,Jun Matsushima,Toru Kimura,Takeshi Ueda,Atsushi Mizokami,Yoshikatsu Kanai,Tomohiko Ichikawa, JOURNAL OF UROLOGY, ELSEVIER SCIENCE INC, Vol. 195, No. 5, p. 1588-1597, 2016/05
  • Novel cystine transporter in renal proximal tubule identified as a "missing partner" of cystinuria-related membrane protein rBAT/SLC3A1, Shushi Nagamori,Pattama Wiriyasermkul,Saya Nakagomi,Hirohisa Okuyama,Suguru Okuda,Ryuichi Ohgaki Ohgaki,Yoshikatsu Kanai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 30, 2016/04
  • Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes, Hirotaka Matsuo,Ken Yamamoto,Hirofumi Nakaoka,Akiyoshi Nakayama,Masayuki Sakiyama,Toshinori Chiba,Atsushi Takahashi,Takahiro Nakamura,Hiroshi Nakashima,Yuzo Takada,Inaho Danjoh,Seiko Shimizu,Junko Abe,Yusuke Kawamura,Sho Terashige,Hiraku Ogata,Seishiro Tatsukawa,Guang Yin,Rieko Okada,Emi Morita,Mariko Naito,Atsumi Tokumasu,Hiroyuki Onoue,Keiichi Iwaya,Toshimitsu Ito,Tappei Takada,Katsuhisa Inoue,Yukio Kato,Yukio Nakamura,Yutaka Sakurai,Hiroshi Suzuki,Yoshikatsu Kanai,Tatsuo Hosoya,Nobuyuki Hamajima,Ituro Inoue,Michiaki Kubo,Kimiyoshi Ichida,Hiroshi Ooyama,Toru Shimizu,Nariyoshi Shinomiya, ANNALS OF THE RHEUMATIC DISEASES, BMJ PUBLISHING GROUP, Vol. 75, No. 4, p. 652-659, 2016/04
  • Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2, Fredrick J. Rosario,Kris Genelyn Dimasuay,Yoshikatsu Kanai,Theresa L. Powell,Thomas Jansson, CLINICAL SCIENCE, PORTLAND PRESS LTD, Vol. 130, No. 7, p. 499-512, 2016/04
  • Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling, Shushi Nagamori,Pattama Wiriyasermkul,Suguru Okuda,Naoto Kojima,Yoshiyuki Hari,Shigeki Kiyonaka,Yasuo Mori,Hideyuki Tominaga,Ryuichi Ohgaki,Yoshikatsu Kanai, AMINO ACIDS, SPRINGER WIEN, Vol. 48, No. 4, p. 1045-1058, 2016/04
  • Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging, Ling Wei,Hideyuki Tominaga,Ryuichi Ohgaki,Pattama Wiriyasermkul,Kohei Hagiwara,Suguru Okuda,Kyoichi Kaira,Noboru Oriuchi,Shushi Nagamori,Yoshikatsu Kanai, Cancer Science, Blackwell Publishing Ltd, Vol. 107, No. 3, p. 347-352, 2016/03/01
  • Clinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinoma, Hiroaki Honjo,Kyoichi Kaira,Tatsuya Miyazaki,Takehiko Yokobori,Yoshikatsu Kanai,Shushi Nagamori,Tetsunari Oyama,Takayuki Asao,Hiroyuki Kuwano, JOURNAL OF SURGICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 113, No. 4, p. 381-389, 2016/03
  • Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals (vol 5, 15057, 2015), Junji Furukawa,Katsuhisa Inoue,Junya Maeda,Tomoya Yasujima,Kinya Ohta,Yoshikatsu Kanai,Tappei Takada,Hirotaka Matsuo,Hiroaki Yuasa, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 6, 2016/03
  • Transport of 3-fluoro-L-alpha-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [F-18]FAMT positron emission tomography, Ling Wei,Hideyuki Tominaga,Ryuichi Ohgaki,Pattama Wiriyasermkul,Kohei Hagiwara,Suguru Okuda,Kyoichi Kaira,Yukio Kato,Noboru Oriuchi,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 130, No. 2, p. 101-109, 2016/02
  • Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1, Shushi Nagamori,Pattama Wiriyasermkul,Meritxell Espino Guarch,Hirohisa Okuyama,Saya Nakagomi,Kenjiro Tadagaki,Yumiko Nishinaka,Susanna Bodoy,Kazuaki Takafuji,Suguru Okuda,Junko Kurokawa,Ryuichi Ohgaki,Virginia Nunes,Manuel Palacín,Yoshikatsu Kanai, Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 3, p. 775-780, 2016/01/19
  • SGLT2 inhibitors: Anti-diabetic drug discovery based on transporter inhibition, Yoshikatsu Kanai, Drug Delivery System, Japan Society of Drug Delivery System, Vol. 31, No. 5, p. 450-461, 2016
  • Expression of a human NPT1/SLC17A1 missense variant which increases urate export, Masayuki Sakiyama,Hirotaka Matsuo,Shushi Nagamori,Wei Ling,Yusuke Kawamura,Akiyoshi Nakayama,Toshihide Higashino,Toshinori Chiba,Kimiyoshi Ichida,Yoshikatsu Kanai,Nariyoshi Shinomiya, NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, TAYLOR & FRANCIS INC, Vol. 35, No. 10-12, p. 536-542, 2016
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Catalytic receptors, Stephen P. H. Alexander,Doriano Fabbro,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 5979-6023, 2015/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: G protein-coupled receptors, Stephen P. H. Alexander,Anthony P. Davenport,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 5744-5869, 2015/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Enzymes, Stephen P. H. Alexander,Doriano Fabbro,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 6024-6109, 2015/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Ligand-gated ion channels, Stephen P. H. Alexander,John A. Peters,Eamonn Kelly,Neil Marrion,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 5870-5903, 2015/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Nuclear hormone receptors, Stephen P. H. Alexander,John A. Cidlowski,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 5956-5978, 2015/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Transporters, Stephen P. H. Alexander,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 6110-6202, 2015/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Overview, Stephen P. H. Alexander,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,O. Peter Buneman,William A. Catterall,John A. Cidlowski,Anthony P. Davenport,Doriano Fabbro,Grace Fan,John C. McGrath,Michael Spedding,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 5729-5743, 2015/12
  • CD98 as a novel prognostic indicator for patients with stage III/IV hypopharyngeal squamous cell carcinoma, Miroru Toyoda,Kyoichi Kaira,Masato Shino,Koichi Sakakura,Katsumasa Takahashi,Yukihiro Takayasu,Hideyuki Tominaga,Noboru Oriuchi,Osamu Nikkuni,Masami Suzuki,Misa Iijima,Norifumi Tsukamoto,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Kazuaki Chikamatsu, HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, WILEY-BLACKWELL, Vol. 37, No. 11, p. 1569-1574, 2015/11
  • Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in cutaneous melanoma, Akira Shimizu,Kyoichi Kaira,Madoka Kato,Masahito Yasuda,Ayumi Takahashi,Hideyuki Tominaga,Noboru Oriuchi,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Takayuki Asao,Osamu Ishikawa, MELANOMA RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 25, No. 5, p. 399-405, 2015/10
  • Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals, Junji Furukawa,Katsuhisa Inoue,Junya Maeda,Tomoya Yasujima,Kinya Ohta,Yoshikatsu Kanai,Tappei Takada,Hirotaka Matsuo,Hiroaki Yuasa, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 5, 2015/10
  • Expression of amino acid transporters (LAT1, ASCT2 and xCT) as clinical significance in hepatocellular carcinoma, Masashi Namikawa,Satoru Kakizaki,Kyoichi Kaira,Hiroki Tojima,Yuichi Yamazaki,Norio Horiguchi,Ken Sato,Noboru Oriuchi,Hideyuki Tominaga,Yutaka Sunose,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Izumi Takeyoshi,Masanobu Yamada, HEPATOLOGY RESEARCH, WILEY-BLACKWELL, Vol. 45, No. 9, p. 1014-1022, 2015/09
  • Expression of Amino Acid Transporters (LAT1 and ASCT2) in Patients with Stage III/IV Laryngeal Squamous Cell Carcinoma, Osamu Nikkuni,Kyoichi Kaira,Minoru Toyoda,Masato Shino,Koichi Sakakura,Katsumasa Takahashi,Hideyuki Tominaga,Noboru Oriuchi,Masami Suzuki,Misa Iijima,Takayuki Asao,Masahiko Nishiyama,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Kazuaki Chikamatsu, PATHOLOGY & ONCOLOGY RESEARCH, SPRINGER, Vol. 21, No. 4, p. 1175-1181, 2015/09
  • L-type amino acid transporter-1 and CD98 expression in bone and soft tissue tumors, Hiromi Koshi,Takaaki Sano,Tadashi Handa,Takashi Yanagawa,Kenichi Saitou,Shushi Nagamori,Yoshikatsu Kanai,Kenji Takagishi,Tetsunari Oyama, PATHOLOGY INTERNATIONAL, WILEY-BLACKWELL, Vol. 65, No. 9, p. 460-467, 2015/09
  • Molecular architecture of the stria vascularis membrane transport system, which is essential for physiological functions of the mammalian cochlea, Satoru Uetsuka,Genki Ogata,Shushi Nagamori,Noriyoshi Isozumi,Fumiaki Nin,Takamasa Yoshida,Shizuo Komune,Tadashi Kitahara,Yoshiaki Kikkawa,Hidenori Inohara,Yoshikatsu Kanai,Hiroshi Hibino, EUROPEAN JOURNAL OF NEUROSCIENCE, WILEY-BLACKWELL, Vol. 42, No. 3, p. 1984-2002, 2015/08
  • Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth, Fredrick J. Rosario,Yoshikatsu Kanai,Theresa L. Powell,Thomas Jansson, OBESITY, WILEY, Vol. 23, No. 8, p. 1663-1670, 2015/08
  • Analysis of the interaction of leucine derivatives with leucine binding protein toward understanding of mTOR activation by leucine, Vol. 128, No. 3, Supplement,, p. S212-S212, 2015/07
  • Expression and functional characterisation of System L amino acid transporters in the human term placenta, Francesca Gaccioli,Irving L. M. H. Aye,Sara Roos,Susanne Lager,Vanessa I. Ramirez,Yoshikatsu Kanai,Theresa L. Powell,Thomas Jansson, REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, BIOMED CENTRAL LTD, Vol. 13, 2015/06
  • Development of a Widely Usable Amino Acid Tracer: Br-76-alpha-Methyl-Phenylalanine for Tumor PET Imaging, Hirofumi Hanaoka,Yasuhiro Ohshima,Yurika Suzuki,Aiko Yamaguchi,Shigeki Watanabe,Tomoya Uehara,Shushi Nagamori,Yoshikatsu Kanai,Noriko S. Ishioka,Yoshito Tsushima,Keigo Endo,Yasushi Arano, JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Vol. 56, No. 5, p. 791-797, 2015/05
  • Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB(0,+), LAT1 and LAT2, Printip Wongthai,Kohei Hagiwara,Yurika Miyoshi,Pattama Wiriyasermkul,Ling Wei,Ryuichi Ohgaki,Itsuro Kato,Kenji Hamase,Shushi Nagamori,Yoshikatsu Kanai, CANCER SCIENCE, WILEY-BLACKWELL, Vol. 106, No. 3, p. 279-286, 2015/03
  • Dysregulation of Retinoic Acid Receptor Diminishes Hepatocyte Permissiveness to Hepatitis B Virus Infection through Modulation of Sodium Taurocholate Cotransporting Polypeptide (NTCP) Expression, Senko Tsukuda,Koichi Watashi,Masashi Iwamoto,Ryosuke Suzuki,Hideki Aizaki,Maiko Okada,Masaya Sugiyama,Soichi Kojima,Yasuhito Tanaka,Masashi Mizokami,Jisu Li,Shuping Tong,Takaji Wakita, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 290, No. 9, p. 5673-5684, 2015/02
  • Clinicopathological significance of ASC amino acid transporter-2 expression in pancreatic ductal carcinoma, Kyoichi Kaira,Yutaka Sunose,Kazuhisa Arakawa,Noriaki Sunaga,Kimihiro Shimizu,Hideyuki Tominaga,Noboru Oriuchi,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Izumi Takeyoshi, HISTOPATHOLOGY, WILEY-BLACKWELL, Vol. 66, No. 2, p. 234-243, 2015/01
  • NPT1/SLC17A1 Is a Renal Urate Exporter in Humans and Its Common Gain-of-Function Variant Decreases the Risk of Renal Underexcretion Gout, Toshinori Chiba,Hirotaka Matsuo,Yusuke Kawamura,Shushi Nagamori,Takashi Nishiyama,Ling Wei,Akiyoshi Nakayama,Takahiro Nakamura,Masayuki Sakiyama,Tappei Takada,Yutaka Taketani,Shino Suma,Mariko Naito,Takashi Oda,Hiroo Kumagai,Yoshinori Moriyama,Kimiyoshi Ichida,Toru Shimizu,Yoshikatsu Kanai,Nariyoshi Shinomiya, ARTHRITIS & RHEUMATOLOGY, WILEY-BLACKWELL, Vol. 67, No. 1, p. 281-287, 2015/01
  • Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer, Kyoichi Kaira,Kazuhisa Arakawa,Kimihiro Shimizu,Noboru Oriuchi,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Izumi Takeyoshi, AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, E-CENTURY PUBLISHING CORP, Vol. 7, No. 2, p. 356-363, 2015
  • Clinical significance of coexpression of L-type amino acid transporter 1 (LAT1) and ASC amino acid transporter 2 (ASCT2) in lung adenocarcinoma, Tomohiro Yazawa,Kimihiro Shimizu,Kyoichi Kaira,Toshiteru Nagashima,Yoichi Ohtaki,Jun Atsumi,Kai Obayashi,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Izumi Takeyoshi, AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, E-CENTURY PUBLISHING CORP, Vol. 7, No. 6, p. 1126-1139, 2015
  • Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors, Kyoichi Kaira,Kazuto Nakamura,Takashi Hirakawa,Hisao Imai,Hideyuki Tominaga,Noboru Oriuchi,Shushi Nagamori,Yoshikatsu Kanai,Norifumi Tsukamoto,Tetsunari Oyama,Takayuki Asao,Takashi Minegishi, AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, E-CENTURY PUBLISHING CORP, Vol. 7, No. 6, p. 1161-1171, 2015
  • CD98 is a promising prognostic biomarker in biliary tract cancer, Kyoichi Kaira,Yutaka Sunose,Noboru Oriuchi,Yoshikatsu Kanai,Izumi Takeyoshi, HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, ZHEJIANG UNIV SCH MEDICINE, Vol. 13, No. 6, p. 654-657, 2014/12
  • Expression of L-type amino acid transporter 1 (LAT1) as a prognostic and therapeutic indicator in multiple myeloma, Atsushi Isoda,Kyoichi Kaira,Masanori Iwashina,Noboru Oriuchi,Hideyuki Tominaga,Shushi Nagamori,Yoshikatsu Kanai,Tetsunari Oyama,Takayuki Asao,Morio Matsumoto,Morio Sawamura, CANCER SCIENCE, WILEY-BLACKWELL, Vol. 105, No. 11, p. 1496-1502, 2014/11
  • Development of a PET/Cerenkov-light hybrid imaging system, Seiichi Yamamoto,Fuka Hamamura,Tadashi Watabe,Hayato Ikeda,Yasukazu Kanai,Hiroshi Watabe,Katsuhiko Kato,Yoshimune Ogata,Jun Hatazawa, MEDICAL PHYSICS, AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, Vol. 41, No. 9, 2014/09
  • Cyclophilin Inhibitors Reduce Phosphorylation of RNA-Dependent Protein Kinase to Restore Expression of IFN-Stimulated Genes in HCV-Infected Cells, Takuji Daito,Koichi Watashi,Ann Sluder,Hirofumi Ohashi,Syo Nakajima,Katyna Borroto-Esoda,Takashi Fujita,Takaji Wakita, GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Vol. 147, No. 2, p. 463-472, 2014/08
  • Glucocorticoid mediates the transcription of OAT-PG, a kidney-specific prostaglandin transporter, Ryo Hatano,Hiroki Mukouchi,Yosuke Matsumoto,Kotoku Kawaguchi,Itsuro Kazama,Yasuhiro Endo,Hiroaki Toyama,Yutaka Ejima,Shin Kurosawa,Yoshikatsu Kanai,Mitsunobu Matsubara,Shinji Asano, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, SPRINGER, Vol. 466, No. 5, p. 925-935, 2014/05
  • Cyclosporin A and Its Analogs Inhibit Hepatitis B Virus Entry Into Cultured Hepatocytes Through Targeting a Membrane Transporter, Sodium Taurocholate Cotransporting Polypeptide (NTCP), Koichi Watashi,Ann Sluder,Takuji Daito,Satoko Matsunaga,Akihide Ryo,Shushi Nagamori,Masashi Iwamoto,Syo Nakajima,Senko Tsukuda,Katyna Borroto-Esoda,Masaya Sugiyama,Yasuhito Tanaka,Yoshikatsu Kanai,Hiroyuki Kusuhara,Masashi Mizokami,Takaji Wakita, HEPATOLOGY, WILEY-BLACKWELL, Vol. 59, No. 5, p. 1726-1737, 2014/05
  • Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer, M. Toyoda,K. Kaira,Y. Ohshima,N. S. Ishioka,M. Shino,K. Sakakura,Y. Takayasu,K. Takahashi,H. Tominaga,N. Oriuchi,S. Nagamori,Y. Kanai,T. Oyama,K. Chikamatsu, BRITISH JOURNAL OF CANCER, NATURE PUBLISHING GROUP, Vol. 110, No. 10, p. 2506-2513, 2014/05
  • Biological significance of fluorine-18-alpha-methyltyrosine (FAMT) uptake on PET in patients with oesophageal cancer, S. Suzuki,K. Kaira,Y. Ohshima,N. S. Ishioka,M. Sohda,T. Yokobori,T. Miyazaki,N. Oriuchi,H. Tominaga,Y. Kanai,N. Tsukamoto,T. Asao,Y. Tsushima,T. Higuchi,T. Oyama,H. Kuwano, BRITISH JOURNAL OF CANCER, NATURE PUBLISHING GROUP, Vol. 110, No. 8, p. 1985-1991, 2014/04
  • Annexin A4-conferred platinum resistance is mediated by the copper transporter ATP7A, Shinya Matsuzaki,Takayuki Enomoto,Satoshi Serada,Kiyoshi Yoshino,Shushi Nagamori,Akiko Morimoto,Takuhei Yokoyama,Ayako Kim,Toshihiro Kimura,Yutaka Ueda,Masami Fujita,Minoru Fujimoto,Yoshikatsu Kanai,Tadashi Kimura,Tetsuji Naka, INTERNATIONAL JOURNAL OF CANCER, WILEY-BLACKWELL, Vol. 134, No. 8, p. 1796-1809, 2014/04
  • ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer, K. Shimizu,K. Kaira,Y. Tomizawa,N. Sunaga,O. Kawashima,N. Oriuchi,H. Tominaga,S. Nagamori,Y. Kanai,M. Yamada,T. Oyama,I. Takeyoshi, BRITISH JOURNAL OF CANCER, NATURE PUBLISHING GROUP, Vol. 110, No. 8, p. 2030-2039, 2014/04
  • Down-regulation of placental mTOR, insulin/IGF- I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon, Jovita V. Kavitha,Fredrick J. Rosario,Mark J. Nijland,Thomas J. McDonald,Guoyao Wu,Yoshikatsu Kanai,Theresa L. Powell,Peter W. Nathanielsz,Thomas Jansson, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 28, No. 3, p. 1294-1305, 2014/03
  • JPH203, an L-Type Amino Acid Transporter 1-Selective Compound, Induces Apoptosis of YD-38 Human Oral Cancer Cells, Dae-Woong Yun,Seul Ah Lee,Min-Gyeong Park,Jae-Sung Kim,Sun-Kyoung Yu,Mi-Ra Park,Su-Gwan Kim,Ji-Su Oh,Chun Sung Kim,Heung-Joong Kim,Jin-Soo Kim,Hong Sung Chun,Yoshikatsu Kanai,Hitoshi Endou,Michael F. Wempe,Do Kyung Kim, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, No. 2, p. 208-217, 2014/02
  • A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility, Masayuki Sakiyama,Hirotaka Matsuo,Seiko Shimizu,Toshinori Chiba,Akiyoshi Nakayama,Yuzo Takada,Takahiro Nakamura,Tappei Takada,Emi Morita,Mariko Naito,Kenji Wakai,Hiroki Inoue,Seishiro Tatsukawa,Junki Sato,Kazumi Shimono,Toshiaki Makino,Takahiro Satoh,Hiroshi Suzuki,Yoshikatsu Kanai,Nobuyuki Hamajima,Yutaka Sakurai,Kimiyoshi Ichida,Toru Shimizu,Nariyoshi Shinomiya, HUMAN CELL, SPRINGER JAPAN KK, Vol. 27, No. 1, p. 1-4, 2014/01
  • Nicotine induces dendritic spine remodeling in cultured hippocampal neurons, Akira Oda,Kanato Yamagata,Saya Nakagomi,Hiroshi Uejima,Pattama Wiriyasermkul,Ryuichi Ohgaki,Shushi Nagamori,Yoshikatsu Kanai,Hidekazu Tanaka, Journal of Neurochemistry, Vol. 128, No. 2, p. 246-255, 2014/01
  • A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility, Masayuki Sakiyama,Hirotaka Matsuo,Seiko Shimizu,Toshinori Chiba,Akiyoshi Nakayama,Yuzo Takada,Takahiro Nakamura,Tappei Takada,Emi Morita,Mariko Naito,Kenji Wakai,Hiroki Inoue,Seishiro Tatsukawa,Junki Sato,Kazumi Shimono,Toshiaki Makino,Takahiro Satoh,Hiroshi Suzuki,Yoshikatsu Kanai,Nobuyuki Hamajima,Yutaka Sakurai,Kimiyoshi Ichida,Toru Shimizu,Nariyoshi Shinomiya, Human Cell, Vol. 27, No. 1, p. 1-4, 2014/01
  • IDENTIFICATION OF A HYPOURICEMIA PATIENT WITH SLC2A9 R380W, A PATHOGENIC MUTATION FOR RENAL HYPOURICEMIA TYPE 2, Toshinori Chiba,Hirotaka Matsuo,Shushi Nagamori,Akiyoshi Nakayama,Yusuke Kawamura,Seiko Shimizu,Masayuki Sakiyama,Makoto Hosoyamada,Sayo Kawai,Rieko Okada,Nobuyuki Hamajima,Yoshikatsu Kanai,Nariyoshi Shinomiya, NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, TAYLOR & FRANCIS INC, Vol. 33, No. 4-6, p. 261-265, 2014
  • Amino acid transporters in cancer, Shushi Nagamori,Yoshikatsu Kanai, Seikagaku, Japanese Biochemical Society, Vol. 86, No. 3, p. 338-344, 2014
  • THE CONCISE GUIDE TO PHARMACOLOGY 2013/14: OVERVIEW, Stephen P. H. Alexander,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,John C. McGrath,William A. Catterall,Michael Spedding,John A. Peters,Anthony J. Harmar, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 170, No. 8, p. 1449-1458, 2013/12
  • YY1 binds to α-synuclein 3′-flanking region SNP and stimulates antisense noncoding RNA expression, Ikuko Mizuta,Kazuaki Takafuji,Yuko Ando,Wataru Satake,Motoi Kanagawa,Kazuhiro Kobayashi,Shushi Nagamori,Takayuki Shinohara,Chiyomi Ito,Mitsutoshi Yamamoto,Nobutaka Hattori,Miho Murata,Yoshikatsu Kanai,Shigeo Murayama,Masanori Nakagawa,Tatsushi Toda, Journal of Human Genetics, Vol. 58, No. 11, p. 711-719, 2013/11
  • Clinicopathological Significance of L-type Amino Acid Transporter 1 (LAT1) Expression in Patients with Adenoid Cystic Carcinoma, Kyoichi Kaira,Minoru Toyoda,Masato Shino,Koichi Sakakura,Katsumasa Takahashi,Hideyuki Tominaga,Noboru Oriuchi,Yoshikatsu Kanai,Tetsunari Oyama,Kazuaki Chikamatsu, PATHOLOGY & ONCOLOGY RESEARCH, SPRINGER, Vol. 19, No. 4, p. 649-656, 2013/10
  • Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer, Kyoichi Kaira,Yutaka Sunose,Yasuhiro Ohshima,Noriko S. Ishioka,Kazuhisa Arakawa,Tetsushi Ogawa,Noriaki Sunaga,Kimihiro Shimizu,Hideyuki Tominaga,Noboru Oriuchi,Hideaki Itoh,Shushi Nagamori,Yoshikatsu Kanai,Aiko Yamaguchi,Atsuki Segawa,Munenori Ide,Masatomo Mori,Tetsunari Oyama,Izumi Takeyoshi, BMC CANCER, BIOMED CENTRAL LTD, Vol. 13, 2013/10
  • The small SLC43 family: Facilitator system L amino acid transporters and the orphan EEG1, Susanna Bodoy,Dimitrios Fotiadis,Claudia Stoeger,Yoshikatsu Kanai,Manuel Palacin, MOLECULAR ASPECTS OF MEDICINE, ELSEVIER SCIENCE BV, Vol. 34, No. 2-3, p. 638-645, 2013/04
  • The SLC1 high-affinity glutamate and neutral amino acid transporter family, Yoshikatsu Kanai,Benjamin Clémençon,Alexandre Simonin,Michele Leuenberger,Martin Lochner,Martin Weisstanner,Matthias A. Hediger, Molecular Aspects of Medicine, Vol. 34, No. 2-3, p. 108-120, 2013/04
  • The SLC3 and SLC7 families of amino acid transporters, Dimitrios Fotiadis,Yoshikatsu Kanai,Manuel Palacin, MOLECULAR ASPECTS OF MEDICINE, ELSEVIER SCIENCE BV, Vol. 34, No. 2-3, p. 139-158, 2013/04
  • L-type amino acid transporter 1 expression is highly correlated with Gleason score in prostate cancer., Segawa A,Nagamori S,Kanai Y,Masawa N,Oyama T, Molecular and clinical oncology, Vol. 1, No. 2, p. 274-280, 2013/03
  • Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells, Fredrick J. Rosario,Yoshikatsu Kanai,Theresa L. Powell,Thomas Jansson, JOURNAL OF PHYSIOLOGY-LONDON, WILEY-BLACKWELL, Vol. 591, No. 3, p. 609-625, 2013/02
  • Biological evaluation of 3-[18F]fluoro-α-methyl-d-tyrosine (d-[18F]FAMT) as a novel amino acid tracer for positron emission tomography, Yasuhiro Ohshima,Hirofumi Hanaoka,Hideyuki Tominaga,Yoshikatsu Kanai,Kyoichi Kaira,Aiko Yamaguchi,Shushi Nagamori,Noboru Oriuchi,Yoshito Tsushima,Keigo Endo,Noriko S. Ishioka, Annals of Nuclear Medicine, Vol. 27, No. 4, p. 314-324, 2013
  • Common dysfunctional variants in ABCG2 are a major cause of early-onset gout, Hirotaka Matsuo,Kimiyoshi Ichida,Tappei Takada,Akiyoshi Nakayama,Hiroshi Nakashima,Takahiro Nakamura,Yusuke Kawamura,Yuzo Takada,Ken Yamamoto,Hiroki Inoue,Yuji Oikawa,Mariko Naito,Asahi Hishida,Kenji Wakai,Chisa Okada,Seiko Shimizu,Masayuki Sakiyama,Toshinori Chiba,Hiraku Ogata,Kazuki Niwa,Makoto Hosoyamada,Atsuyoshi Mori,Nobuyuki Hamajima,Hiroshi Suzuki,Yoshikatsu Kanai,Yutaka Sakurai,Tatsuo Hosoya,Toru Shimizu,Nariyoshi Shinomiya, Scientific Reports, Vol. 3, 2013
  • Diagnostic usefulness of 18F-FAMT PET and L-type amino acid transporter 1 (LAT1) expression in oral squamous cell carcinoma, Aiko Nobusawa,Mai Kim,Kyoichi Kaira,Go Miyashita,Akihide Negishi,Noboru Oriuchi,Tetsuya Higuchi,Yoshito Tsushima,Yoshikatsu Kanai,Satoshi Yokoo,Tetsunari Oyama, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 40, No. 11, p. 1692-1700, 2013
  • Decreased Expression of a Novel Prostaglandin Transporter, OAT-PG, Facilitates Renocortical PGE(2) Accumulation during Rat Pregnancy, Itsuro Kazama,Mitsunobu Matsubara,Yoshikatsu Kanai,Ryo Hatano,Shinji Asano,Yasuhiro Endo,Hiroaki Toyama,Yutaka Ejima,Shin Kurosawa,Yoshio Maruyama, GYNECOLOGIC AND OBSTETRIC INVESTIGATION, KARGER, Vol. 76, No. 3, p. 163-170, 2013
  • IUPHAR-DB: updated database content and new features, Joanna L. Sharman,Helen E. Benson,Adam J. Pawson,Veny Lukito,Chidochangu P. Mpamhanga,Vincent Bombail,Anthony P. Davenport,John A. Peters,Michael Spedding,Anthony J. Harmar, NUCLEIC ACIDS RESEARCH, OXFORD UNIV PRESS, Vol. 41, No. D1, p. D1083-D1088, 2013/01
  • NRFL-1, the C. elegans NHERF orthologue, interacts with amino acid transporter 6 (AAT-6) for age-dependent maintenance of AAT-6 on the membrane, Kohei Hagiwara,Shushi Nagamori,Yasuhiro M. Umemura,Ryuichi Ohgaki,Hidekazu Tanaka,Daisuke Murata,Saya Nakagomi,Kazuko H. Nomura,Eriko Kage-Nakadai,Shohei Mitani,Kazuya Nomura,Yoshikatsu Kanai, PLoS ONE, Vol. 7, No. 8, 2012/08/15
  • Transport of 3-Fluoro-L-alpha-Methyl-Tyrosine by Tumor-Upregulated L-Type Amino Acid Transporter 1: A Cause of the Tumor Uptake in PET, Pattama Wiriyasermkul,Shushi Nagamori,Hideyuki Tominaga,Noboru Oriuchi,Kyoichi Kaira,Hidekazu Nakao,Takeru Kitashoji,Ryuichi Ohgaki,Hidekazu Tanaka,Hitoshi Endou,Keigo Endo,Hiroyuki Sakurai,Yoshikatsu Kanai, JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Vol. 53, No. 8, p. 1253-1261, 2012/08
  • Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With alpha-Alkyl Moieties, Narakorn Khunweeraphong,Shushi Nagamori,Pattama Wiriyasermku,Yumiko Nishinaka,Printip Wongthai,Ryuichi Ohgaki,Hidekazu Tanaka,Hideyuki Tominaga,Hiroyuki Sakurai,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 119, No. 4, p. 368-380, 2012/08
  • Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer, K. Kaira,Y. Sunose,K. Arakawa,T. Ogawa,N. Sunaga,K. Shimizu,H. Tominaga,N. Oriuchi,H. Itoh,S. Nagamori,Y. Kanai,A. Segawa,M. Furuya,M. Mori,T. Oyama,I. Takeyoshi, BRITISH JOURNAL OF CANCER, NATURE PUBLISHING GROUP, Vol. 107, No. 4, p. 632-638, 2012/08
  • Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons, Hidekazu Tanaka,Kazuaki Takafuji,Akihiko Taguchi,Pattama Wiriyasermkul,Ryuichi Ohgaki,Shushi Nagamori,Pann-Ghill Suh,Yoshikatsu Kanai, NEUROCHEMISTRY INTERNATIONAL, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 61, No. 2, p. 240-250, 2012/07
  • Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth, Fredrick J. Rosario,Michael A. Schumacher,Jean Jiang,Yoshikatsu Kanai,Theresa L. Powell,Thomas Jansson, JOURNAL OF PHYSIOLOGY-LONDON, WILEY-BLACKWELL, Vol. 590, No. 6, p. 1495-1509, 2012/03
  • Sex hormones induce a gender-related difference in renal expression of a novel prostaglandin transporter, OAT-PG, influencing basal PGE 2 concentration, Ryo Hatano,Kimitaka Onoe,Masaya Obara,Mitsunobu Matsubara,Yoshikatsu Kanai,Shigeaki Muto,Shinji Asano, American Journal of Physiology - Renal Physiology, Vol. 302, No. 3, p. F342-F349, 2012/02
  • Sex hormones induce a gender-related difference in renal expression of a novel prostaglandin transporter, OAT-PG, influencing basal PGE(2) concentration, Ryo Hatano,Kimitaka Onoe,Masaya Obara,Mitsunobu Matsubara,Yoshikatsu Kanai,Shigeaki Muto,Shinji Asano, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 302, No. 3, p. F342-F349, 2012/02
  • Correlation of L-type amino acid transporter 1 and CD98 expression with triple negative breast cancer prognosis, Mio Furuya,Jun Horiguchi,Hiroki Nakajima,Yoshikatsu Kanai,Tetsunari Oyama, CANCER SCIENCE, WILEY-BLACKWELL, Vol. 103, No. 2, p. 382-389, 2012/02
  • Cancer drug delivery targeting amino acid transporters, Yoshikatsu Kanai, Drug Delivery System, Vol. 27, No. 5, p. 342-349, 2012
  • How to use the IUPHAR receptor database to navigate pharmacological data., Vol. 897, p. 15-29, 2012
  • L-Type Amino Acid Transporter 1 (LAT1) Expression in Malignant Pleural Mesothelioma, Kyoichi Kaira,Noboru Oriuchi,Toshiaki Takahashi,Kazuo Nakagawa,Yasuhisa Ohde,Takehiro Okumura,Haruyasu Murakami,Takehito Shukuya,Hirotsugu Kenmotsu,Tateaki Naito,Yoshikatsu Kanai,Masahiro Endo,Haruhiko Kondo,Takashi Nakajima,Nobuyuki Yamamoto, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 31, No. 12, p. 4075-4082, 2011/12
  • A Seven-Transmembrane Receptor That Mediates Avoidance Response to Dihydrocaffeic Acid, a Water-Soluble Repellent in Caenorhabditis elegans, Reina Aoki,Tatsurou Yagami,Hiroyuki Sasakura,Ken-ichi Ogura,Yasuhiro Kajihara,Masakazu Ibi,Takeaki Miyamae,Fumio Nakamura,Taro Asakura,Yoshikatsu Kanai,Yoshimi Misu,Yuichi Iino,Marina Ezcurra,William R. Schafer,Ikue Mori,Yoshio Goshima, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 31, No. 46, p. 16603-16610, 2011/11
  • Relationship between LAT1 Expression and Response to Platinum-based Chemotherapy in Non-small Cell Lung Cancer Patients with Postoperative Recurrence, Kyoichi Kaira,Toshiaki Takahashi,Haruyasu Murakami,Takehito Shukuya,Hirotsugu Kenmotsu,Tateaki Naito,Noboru Oriuchi,Yoshikatsu Kanai,Masahiro Endo,Haruhiko Kondo,Takashi Nakajima,Nobuyuki Yamamoto, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 31, No. 11, p. 3775-3782, 2011/11
  • Transportsomes and channelsomes Are they functional units for physiological responses?, Yasuo Mori,Shigeki Kiyonaka,Yoshikatsu Kanai, CHANNELS, LANDES BIOSCIENCE, Vol. 5, No. 5, p. 385-388, 2011/09
  • Role of amino acid transporter LAT2 in the activation of mTORC1 pathway and the pathogenesis of crescentic glomerulonephritis, Ryota Kurayama,Noriko Ito,Yukino Nishibori,Daisuke Fukuhara,Yoshihiro Akimoto,Eiji Higashihara,Yasuhito Ishigaki,Yoshimichi Sai,Ken-ichi Miyamoto,Hitoshi Endou,Yoshikatstu Kanai,Kunimasa Yan, LABORATORY INVESTIGATION, NATURE PUBLISHING GROUP, Vol. 91, No. 7, p. 992-1006, 2011/07
  • Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters, Fredrick J. Rosario,Nina Jansson,Yoshikatsu Kanai,Puttur D. Prasad,Theresa L. Powell,Thomas Jansson, ENDOCRINOLOGY, ENDOCRINE SOC, Vol. 152, No. 3, p. 1119-1129, 2011/03
  • LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer, Kyoichi Kaira,Noboru Oriuchi,Toshiaki Takahashi,Kazuo Nakagawa,Yasuhisa Ohde,Takehiro Okumura,Haruyasu Murakami,Takehito Shukuya,Hirotsugu Kenmotsu,Tateaki Naito,Yoshikatsu Kanai,Masahiro Endo,Haruhiko Kondo,Takashi Nakajima,Nobuyuki Yamamoto, AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, E-CENTURY PUBLISHING CORP, Vol. 3, No. 5, p. 468-U104, 2011
  • ABCG2 IS A HIGH-CAPACITY URATE TRANSPORTER AND ITS GENETIC IMPAIRMENT INCREASES SERUM URIC ACID LEVELS IN HUMANS, Akiyoshi Nakayama,Hirotaka Matsuo,Tappei Takada,Kimiyoshi Ichida,Takahiro Nakamura,Yuki Ikebuchi,Kousei Ito,Tatsuo Hosoya,Yoshikatsu Kanai,Hiroshi Suzuki,Nariyoshi Shinomiya, NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, TAYLOR & FRANCIS INC, Vol. 30, No. 12, p. 1091-1097, 2011
  • IDENTIFICATION OF ABCG2 DYSFUNCTION AS A MAJOR FACTOR CONTRIBUTING TO GOUT, H. Matsuo,T. Takada,K. Ichida,T. Nakamura,A. Nakayama,Y. Takada,C. Okada,Y. Sakurai,T. Hosoya,Y. Kanai,H. Suzuki,N. Shinomiya, NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, TAYLOR & FRANCIS INC, Vol. 30, No. 12, p. 1098-1104, 2011
  • PATHOGENIC GLUT9 MUTATIONS CAUSING RENAL HYPOURICEMIA TYPE 2 (RHUC2), Y. Kawamura,H. Matsuo,T. Chiba,S. Nagamori,A. Nakayama,H. Inoue,Y. Utsumi,T. Oda,J. Nishiyama,Y. Kanai,N. Shinomiya, NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, TAYLOR & FRANCIS INC, Vol. 30, No. 12, p. 1105-1111, 2011
  • Receptor for Activated C-Kinase 1 Regulates the Cell Surface Expression and Function of ATP Binding Cassette G2, Yuki Ikebuchi,Kousei Ito,Tappei Takada,Naohiko Anzai,Yoshikatsu Kanai,Hiroshi Suzuki, DRUG METABOLISM AND DISPOSITION, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 38, No. 12, p. 2320-2328, 2010/12
  • Inhibition of L-type Amino Acid Transporter 1 Has Antitumor Activity in Non-small Cell Lung Cancer, Hisao Imai,Kyoichi Kaira,Noboru Oriuchi,Kimihiro Shimizu,Hideyuki Tominaga,Noriko Yanagitani,Noriaki Sunaga,Tamotsu Ishizuka,Shushi Nagamori,Kanyarat Promchan,Takashi Nakajima,Nobuyuki Yamamoto,Masatomo Mori,Yoshikatsu Kanai, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 30, No. 12, p. 4819-4828, 2010/12
  • Comparison of L-type amino acid transporter 1 expression and L-[3-F-18]-alpha-methyl tyrosine uptake in outcome of non-small cell lung cancer, Kyoichi Kaira,Noboru Oriuchi,Kimihiro Shimizu,Hisao Imai,Hideyuki Tominaga,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Tamotsu Ishizuka,Yoshikatsu Kanai,Tetsunari Oyama,Masatomo Mori,Keigo Endo, NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER SCIENCE INC, Vol. 37, No. 8, p. 911-916, 2010/11
  • L-type Amino-Acid Transporter 1 Expression Predicts the Response to Preoperative Hyperthermo-Chemoradiotherapy for Advanced Rectal Cancer, Takeshi Ebara,Kyoichi Kaira,Jun-Ichi Saito,Mariko Shioya,Takayuki Asao,Takeo Takahashi,Hideyuki Sakurai,Yoshikatsu Kanai,Hiroyuki Kuwano,Takashi Nakano, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 30, No. 10, p. 4223-4227, 2010/10
  • Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in surgically resectable stage III non-small cell lung cancer, Kyoichi Kaira,Noboru Oriuchi,Hisao Imai,Kimihiro Shimizu,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Osamu Kawashima,Yosuke Kamide,Tamotsu Ishizuka,Yoshikatsu Kanai,Takashi Nakajima,Masatomo Mori, EXPERIMENTAL AND THERAPEUTIC MEDICINE, SPANDIDOS PUBL LTD, Vol. 1, No. 5, p. 799-808, 2010/09
  • Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo, Akimitsu Maeda,Shuichi Tsuruoka,Kentarou Ushijima,Yoshikatsu Kanai,Hitoshi Endou,Kazuyuki Saito,Etsuko Miyamoto,Akio Fujimura, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 640, No. 1-3, p. 168-171, 2010/08
  • A Novel Transporter of SLC22 Family Specifically Transports Prostaglandins and Co-localizes with 15-Hydroxyprostaglandin Dehydrogenase in Renal Proximal Tubules, Katsuko Shiraya,Taku Hirata,Ryo Hatano,Shushi Nagamori,Pattama Wiriyasermkul,Promsuk Jutabha,Mitsunobu Matsubara,Shigeaki Muto,Hidekazu Tanaka,Shinji Asano,Naohiko Anzai,Hitoshi Endou,Akira Yamada,Hiroyuki Sakurai,Yoshikatsu Kanai, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 285, No. 29, p. 22141-22151, 2010/07
  • Inhibition of L-Type Amino Acid Transporter Modulates the Expression of Cell Cycle Regulatory Factors in KB Oral Cancer Cells, Chun Sung Kim,In-Sung Moon,Ju-Hyun Park,Woo-Cheol Shin,Hong Sung Chun,Sook-Young Lee,Joong-Ki Kook,Heung-Joong Kim,Joo-Cheol Park,Hitoshi Endou,Yoshikatsu Kanai,Byung-Kwon Lee,Do Kyung Kim, BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, Vol. 33, No. 7, p. 1117-1121, 2010/07
  • Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout, Wako Urano,Atsuo Taniguchi,Naohiko Anzai,Eisuke Inoue,Yoshikatsu Kanai,Mariko Yamanaka,Hitoshi Endou,Naoyuki Kamatani,Hisashi Yamanaka, ANNALS OF THE RHEUMATIC DISEASES, B M J PUBLISHING GROUP, Vol. 69, No. 6, p. 1232-1234, 2010/06
  • Properties of L-Type Amino Acid Transporter 1 in Epidermal Ovarian Cancer, Masahiko Kaji,Maryam Kabir-Salmani,Naohiko Anzai,Chun Ji Jin,Yoshihiro Akimoto,Ayako Horita,Atsuhiko Sakamoto,Yoshikatsu Kanai,Hiroyuki Sakurai,Mitsutoshi Iwashita, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, LIPPINCOTT WILLIAMS & WILKINS, Vol. 20, No. 3, p. 329-336, 2010/04
  • L-type Amino-acid Transporter 1 Expression Predicts the Response to Preoperative Hyperthermo-chemoradiotherapy for Locally Advanced Rectal Cancer, T. Ebara,K. Kaira,M. Shioya,T. Asao,T. Takahashi,H. Sakurai,Y. Kanai,H. Kuwano,T. Nakano, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ELSEVIER SCIENCE INC, Vol. 78, No. 3, p. S330-S331, 2010
  • A pathogenic C-terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7, Tomohiro Numata,Shigeki Kiyonaka,Yoshikatsu Kanai,Yasuo Mori, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 60, 2010
  • Pathogenic C-terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7, Shigeki Kiyonaka,Kyoko Miyagi,Kazunori Yamada,Takafumi Miki,Emiko Mori,Kenta Kato,Tomohiro Numata,Yuichi Sawaguchi,Toru Kimura,Yoshikatsu Kanai,Yasuo Mori, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 202P-202P, 2010
  • l-Type amino acid transporter 1 inhibitors inhibit tumor cell growth, Koji Oda,Noriko Hosoda,Hiroshi Endo,Kunio Saito,Kenji Tsujihara,Michio Yamamura,Takeshi Sakata,Naohiko Anzai,Michael F. Wempe,Yoshikatsu Kanai,Hitoshi Endou, CANCER SCIENCE, WILEY-BLACKWELL PUBLISHING, INC, Vol. 101, No. 1, p. 173-179, 2010/01
  • CD98 Expression Is Associated with Poor Prognosis in Resected Non-Small-Cell Lung Cancer with Lymph Node Metastases, Kyoichi Kaira,Noboru Oriuchi,Hisao Imai,Kimihiro Shimizu,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Osamu Kawashima,Yosuke Kamide,Tamotsu Ishizuka,Yoshikatsu Kanai,Takashi Nakajima,Masatomo Mori, ANNALS OF SURGICAL ONCOLOGY, SPRINGER, Vol. 16, No. 12, p. 3473-3481, 2009/12
  • A Pathogenic C Terminus-truncated Polycystin-2 Mutant Enhances Receptor-activated Ca2+ Entry via Association with TRPC3 and TRPC7, Kyoko Miyagi,Shigeki Kiyonaka,Kazunori Yamada,Takafumi Miki,Emiko Mori,Kenta Kato,Tomohiro Numata,Yuichi Sawaguchi,Takuro Numaga,Toru Kimura,Yoshikatsu Kanai,Mitsuhiro Kawano,Minoru Wakamori,Hideki Nomura,Ichiro Koni,Masakazu Yamagishi,Yasuo Mori, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 284, No. 49, p. 34400-34412, 2009/12
  • Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4, Yuki Ikebuchi,Tappei Takada,Kousei Ito,Takashi Yoshikado,Naohiko Anzai,Yoshikatsu Kanai,Hiroshi Suzuki, HEPATOLOGY RESEARCH, WILEY-BLACKWELL PUBLISHING, INC, Vol. 39, No. 11, p. 1091-1107, 2009/11
  • F-18-FMT Uptake Seen Within Primary Cancer on PET Helps Predict Outcome of Non-Small Cell Lung Cancer, Kyoichi Kaira,Noboru Oriuchi,Kimihiro Shimizu,Hideyuki Tominaga,Noriko Yanagitani,Noriaki Sunaga,Tamotsu Ishizuka,Yoshikatsu Kanai,Masatomo Mori,Keigo Endo, JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Vol. 50, No. 11, p. 1770-1776, 2009/11
  • Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population, Hirotaka Matsuo,Tappei Takada,Kimiyoshi Ichida,Takahiro Nakamura,Akiyoshi Nakayama,Yuki Ikebuchi,Kousei Ito,Yasuyoshi Kusanagi,Toshinori Chiba,Shin Tadokoro,Yuzo Takada,Yuji Oikawa,Hiroki Inoue,Koji Suzuki,Rieko Okada,Junichiro Nishiyama,Hideharu Domoto,Satoru Watanabe,Masanori Fujita,Yuji Morimoto,Mariko Naito,Kazuko Nishio,Asahi Hishida,Kenji Wakai,Yatami Asai,Kazuki Niwa,Keiko Kamakura,Shigeaki Nonoyama,Yutaka Sakurai,Tatsuo Hosoya,Yoshikatsu Kanai,Hiroshi Suzuki,Nobuyuki Hamajima,Nariyoshi Shinomiya, SCIENCE TRANSLATIONAL MEDICINE, AMER ASSOC ADVANCEMENT SCIENCE, Vol. 1, No. 5, 2009/11
  • Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma, Kyoichi Kaira,Noboru Oriuchi,Hisao Imai,Kimihiro Shimizu,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Tamotsu Ishizuka,Yoshikatsu Kanai,Takashi Nakajima,Masatomo Mori, LUNG CANCER, ELSEVIER IRELAND LTD, Vol. 66, No. 1, p. 120-126, 2009/10
  • Amino acid transporter LAT3 is required for podocyte development and function, Yuji Sekine,Yukino Nishibori,Yoshihiro Akimoto,Akihiko Kudo,Noriko Ito,Daisuke Fukuhara,Ryota Kurayama,Eiji Higashihara,Ellappan Babu,Yoshikatsu Kanai,Katsuhiko Asanuma,Michio Nagata,Årindam Majumdar,Karl Tryggvason,Kunimasa Yan, Journal of the American Society of Nephrology, Vol. 20, No. 7, p. 1586-1596, 2009/07
  • Amino Acid Transporter LAT3 Is Required for Podocyte Development and Function, Yuji Sekine,Yukino Nishibori,Yoshihiro Akimoto,Akihiko Kudo,Noriko Ito,Daisuke Fukuhara,Ryota Kurayama,Eiji Higashihara,Ellappan Babu,Yoshikatsu Kanai,Katsuhiko Asanuma,Michio Nagata,Arindam Majumdar,Karl Tryggvason,Kunimasa Yan, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, AMER SOC NEPHROLOGY, Vol. 20, No. 7, p. 1586-1596, 2009/07
  • L-Type Amino Acid Transporter 1 (LAT1) Is Frequently Expressed in Thymic Carcinomas but Is Absent in Thymomas, Kyoichi Kaira,Noboru Oriuchi,Hisao Imai,Kimihiro Shimizu,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Tamotsu Ishizuka,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Masatomo Mori, JOURNAL OF SURGICAL ONCOLOGY, WILEY-LISS, Vol. 99, No. 7, p. 433-438, 2009/06
  • L-type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non-small cell lung cancer, Hisao Imai,Kyoichi Kaira,Noboru Oriuchi,Noriko Yanagitani,Noriaki Sunaga,Tamotsu Ishizuka,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Masatomo Mori, HISTOPATHOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 54, No. 7, p. 804-813, 2009/06
  • System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line, Kohichi Yamauchi,Hiroyuki Sakurai,Toru Kimura,Pattama Wiriyasermkul,Shushi Nagamori,Yoshikatsu Kanai,Naoyuki Kohno, CANCER LETTERS, ELSEVIER IRELAND LTD, Vol. 276, No. 1, p. 95-101, 2009/04
  • Correlation of angiogenesis with F-18-FMT and F-18-FDG uptake in non-small cell lung cancer, Kyoichi Kaira,Noboru Oriuchi,Kimihiro Shimizu,Tomohiro Ishikita,Tetsuya Higuchi,Hisao Imai,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Tamotsu Ishizuka,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Keigo Endo,Masatomo Mori, CANCER SCIENCE, WILEY-BLACKWELL, Vol. 100, No. 4, p. 753-758, 2009/04
  • Evaluation of thoracic tumors with F-18-FMT and F-18-FDG PET-CT: A clinicopathological study, Kyoichi Kaira,Noboru Oriuchi,Kimihiro Shimizu,Tomohiro Ishikita,Tetsuya Higuchi,Hisao Imai,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Tamotsu Ishizuka,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Keigo Endo,Masatomo Mori, INTERNATIONAL JOURNAL OF CANCER, WILEY-BLACKWELL, Vol. 124, No. 5, p. 1152-1160, 2009/03
  • Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung, Kyoichi Kaira,Noboru Oriuchi,Hisao Imai,Kimihiro Shimizu,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Tamotsu Ishizuka,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Masatomo Mori, CANCER SCIENCE, WILEY-BLACKWELL PUBLISHING, INC, Vol. 100, No. 2, p. 249-254, 2009/02
  • Posttranslational regulation of Abcc2 expression by SUMOylation system, Satoko Minami,Kousei Ito,Masashi Honma,Yuki Ikebuchi,Naohiko Anzai,Yoshikatsu Kanai,Tamotsu Nishida,Sachiko Tsukita,Shuichi Sekine,Toshiharu Horie,Hiroshi Suzuki, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 296, No. 2, p. G406-G413, 2009/02
  • A novel role of the C-terminus of b(0,+)AT in the ER-Golgi trafficking of the rBAT-b(0,+)AT heterodimeric amino acid transporter, Shinichi Sakamoto,Arthit Chairoungdua,Shushi Nagamori,Pattama Wiriyasermkul,Kanyarat Promchan,Hidekazu Tanaka,Toru Kimura,Takeshi Ueda,Masaaki Fujimura,Yasuhiro Shigeta,Yukio Naya,Koichiro Akakura,Haruo Ito,Hitoshi Endou,Tomohiko Ichikawa,Yoshikatsu Kanai, BIOCHEMICAL JOURNAL, PORTLAND PRESS LTD, Vol. 417, No. 2, p. 441-448, 2009/01
  • L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer, Takeshi Sakata,Golam Ferdous,Tomoko Tsuruta,Takefumi Satoh,Shiro Baba,Tomoko Muto,Akinori Ueno,Yoshikatsu Kanai,Hitoshi Endou,Isao Okayasu, PATHOLOGY INTERNATIONAL, WILEY-BLACKWELL PUBLISHING, INC, Vol. 59, No. 1, p. 7-18, 2009/01
  • Significance of System L Amino Acid Transporter 1 (LAT-1) and 4F2 Heavy Chain (4F2hc) Expression in Human Developing Intestines, Chikara Ohno,Yohko Nakanishi,Taku Honma,Akihiro Henmi,Masahiko Sugitani,Yoshikatsu Kanai,Norimichi Nemoto, ACTA HISTOCHEMICA ET CYTOCHEMICA, JAPAN SOC HISTOCHEMISTRY & CYTOCHEMISTRY, Vol. 42, No. 3, p. 73-81, 2009
  • Regulation of placental amino acid transporter activity by mammalian target of rapamycin, S. Roos,Y. Kanai,P. D. Prasad,T. L. Powell,T. Jansson, AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 296, No. 1, p. C142-C150, 2009/01
  • l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms, Kyoichi Kaira,Noboru Oriuchi,Hisao Imai,Kimihiro Shimizu,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Shigebumi Tanaka,Tamotsu Ishizuka,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Masatomo Mori, CANCER SCIENCE, WILEY-BLACKWELL PUBLISHING, INC, Vol. 99, No. 12, p. 2380-2386, 2008/12
  • Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia, Hirotaka Matsuo,Toshinori Chiba,Shushi Nagamori,Akiyoshi Nakayama,Hideharu Domoto,Kanokporn Phetdee,Pattama Wiriyasermkul,Yuichi Kikuchi,Takashi Oda,Junichiro Nishiyama,Takahiro Nakamura,Yuji Morimoto,Keiko Kamakura,Yutaka Sakurai,Shigeaki Nonoyama,Yoshikatsu Kanai,Nariyoshi Shinomiya, AMERICAN JOURNAL OF HUMAN GENETICS, CELL PRESS, Vol. 83, No. 6, p. 744-751, 2008/12
  • Establishment and Characterization of Mammalian Cell Lines Stably Expressing Human L-Type Amino Acid Transporters, Emiko Morimoto,Yoshikatsu Kanai,Do Kyung Kim,Arthit Chairoungdua,Hye Won Choi,Michael F. Wempe,Naohiko Anzai,Hitoshl Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 108, No. 4, p. 505-516, 2008/12
  • L-Glutamate Enhances Methylmercury Toxicity by Synergistically Increasing Oxidative Stress, Sirirat Amonpatumrat,Hiroyuki Sakurai,Pattama Wiriyasermkul,Narakorn Khunweeraphong,Shushi Nagamori,Hidekazu Tanaka,Pawinee Piyachaturawat,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 108, No. 3, p. 280-289, 2008/11
  • Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells, Akimitsu Maeda,Shuichi Tsuruoka,Yoshikatsu Kanai,Hitoshi Endou,Kazuyuki Saito,Etsuko Miyamoto,Akio Fujimura, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 596, No. 1-3, p. 166-172, 2008/10
  • Characterization of Amino Acid Transport System L in HTB-41 Human Salivary Gland Epidermoid Carcinoma Cells, No-Seung Park,Su-Gwan Kim,Hak-Kyun Kim,Seong-Yong Moon,Chun Sung Kim,Seon-Ho Cho,Yoshikatsu Kanai,Hitoshi Endou,Do Kyung Kim, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 28, No. 5A, p. 2649-2655, 2008/09
  • Roles of organic anion transporters in the renal excretion of perfluorooctanoic acid, Hatsuki Nakagawa,Taku Hirata,Tomohiro Terada,Promsuk Jutabha,Daisaku Miura,Kouji H. Harada,Kayoko Inoue,Naohiko Anzai,Hitoshi Endou,Ken-ichi Inui,Yoshikatsu Kanai,Akio Koizumi, BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, WILEY-BLACKWELL, Vol. 103, No. 1, p. 1-8, 2008/07
  • BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells, Chun Sung Kim,Seon-Ho Cho,Hong Sung Chun,Sook-Young Lee,Hitoshi Endou,Yoshikatsu Kanai,Do Kyung Kim, BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, Vol. 31, No. 6, p. 1096-1100, 2008/06
  • [Molecular mechanisms of urate transport in renal tubules: localization and function of urate transporters]., Kanai Y, Nihon rinsho. Japanese journal of clinical medicine, Vol. 66, No. 4, p. 659-666, 2008/04
  • The membrane-spanning domain of CD98 heavy chain promotes α<inf>v</inf>β<inf>3</inf> integrin signals in human extravillous trophoblasts, Maryam Kabir-Salmani,Michiko N. Fukuda,Masami Kanai-Azuma,Nesar Ahmed,Shigetatsu Shiokawa,Yoshihiro Akimoto,Keiji Sakai,Seishi Nagamori,Yoshikatsu Kanai,Kazuhiro Sugihara,Mitsutoshi Iwashita, Molecular Endocrinology, Vol. 22, No. 3, p. 707-715, 2008/03
  • Differential expression of system L amino acid transporters during wound healing process in the skin of young and old rats, Moon-Jin Jeong,Chun Sung Kim,Joo-Cheol Park,Heung-Joong Kim,Yeong Mu Ko,Kyung Jin Park,Soon-Jeong Jeong,Hitoshi Endou,Yoshikatsu Kanai,Do-Seon Lim,Do Kyung Kim, BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, Vol. 31, No. 3, p. 395-399, 2008/03
  • Mouse organic anion transporter 2 (mOat2) mediates the transport of short chain fatty acid propionate, Rafiqul Islam,Naohiko Anzai,Nesar Ahmed,Babu Ellapan,Chun Ji Jin,Sunena Srivastava,Daisaku Miura,Toshiyuki Fukutomi,Yoshikatsu Kanai,Hitoshi Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 106, No. 3, p. 525-528, 2008/03
  • Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells, Keiichi Kobayashi,Akiko Ohnishi,Jutabha Promsuk,Saki Shimizu,Yoshikatsu Kanai,Yoshiaki Shiokawa,Motoo Nagane, NEUROSURGERY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 62, No. 2, p. 493-503, 2008/02
  • Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I-III nonsmall cell lung cancer, K. Kaira,N. Oriuchi,H. Imai,K. Shimizu,N. Yanagitani,N. Sunaga,T. Hisada,S. Tanaka,T. Ishizuka,Y. Kanai,H. Endou,T. Nakajima,M. Mori, BRITISH JOURNAL OF CANCER, NATURE PUBLISHING GROUP, Vol. 98, No. 4, p. 742-748, 2008/02
  • [Topics in renal physiology: transgenic animals and cellular signaling]., Kanai Y, Nihon Jinzo Gakkai shi, Vol. 50, No. 1, p. 1-4, 2008
  • Expression of L-type amino acid transporter 1 (LAT1) in neuroendocrine tumors of the lung, Kyoichi Kaira,Noboru Oriuchi,Hisao Imai,Kimihiro Shimizu,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Osamu Kawashima,Hironobu Iijima,Tamotsu Ishizuka,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Masatomo Mori, PATHOLOGY RESEARCH AND PRACTICE, ELSEVIER GMBH, URBAN & FISCHER VERLAG, Vol. 204, No. 8, p. 553-561, 2008
  • Functional and immunochemical characterization of a novel organic anion transporter oat8 (Slc22a9) in rat renal collecting duct, Hirokazu Yokoyama,Naohiko Anzai,Marija Ljubojevic,Naoko Ohtsu,Takeshi Sakata,Hiroki Miyazaki,Hiroshi Nonoguchi,Rafiqul Islam,Maristella Lika Onozato,Akihiro Tojo,Kimio Tomita,Yoshikatsu Kanai,Takashi Igarashi,Ivan Sabolic,Hitoshi Endou, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, KARGER, Vol. 21, No. 4, p. 269-278, 2008
  • Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: A clinicopathologic study, Kyoichi Kaira,Noboru Oriuchi,Yoshimi Otani,Kimihiro Shimizu,Shigebumi Tanaka,Hisao Imai,Noriko Yanagitani,Noriaki Sunaga,Takeshi Hisada,Tamotsu Ishizuka,Kunio Dobashi,Yoshikatsu Kanai,Hitoshi Endou,Takashi Nakajima,Keigo Endo,Masatomo Mori, CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 13, No. 21, p. 6369-6378, 2007/11
  • Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract, Kuniaki Nakanishi,Sho Ogata,Hirotaka Matsuo,Yoshikatsu Kanai,Hitoshi Endou,Sadayuki Hiroi,Susumu Tominaga,Shinsuke Aida,Hiroyasu Kasamatsu,Toshiaki Kawai, VIRCHOWS ARCHIV, SPRINGER, Vol. 451, No. 3, p. 681-690, 2007/09
  • Spermatogenesis in aged rats after prenatal 3,3',4,4',5-pentachlorobiphenyl exposure, Shin Wakui,Fumio Takagi,Tomoko Muto,Kiyofumi Yokoo,Shyou Hirono,Yasuko Kobayashi,Kinji Shirota,Fumiaki Akahori,Yoshihiko Suzuki,Hiroshi Hano,Hitoshi Endou,Yoshikatsu Kanai, TOXICOLOGY, ELSEVIER IRELAND LTD, Vol. 238, No. 2-3, p. 186-191, 2007/09
  • Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate, Ho Jung Shin,Naohiko Anzai,Atsushi Enomoto,Xin He,Do Kyung Kim,Hitoshi Endou,Yoshikatsu Kanai, HEPATOLOGY, JOHN WILEY & SONS INC, Vol. 45, No. 4, p. 1046-1055, 2007/04
  • Gene expression profiles in T24 human bladder carcinoma cells by inhibiting an L-type amino acid transporter, LAT1, Shadi Baniasadi,Arthit Chairoungdua,Yuji Iribe,Yoshikatsu Kanai,Hitoshi Endou,Ken-ichi Aisaki,Katsuhide Igarashi,Jun Kanno, ARCHIVES OF PHARMACAL RESEARCH, PHARMACEUTICAL SOC KOREA, Vol. 30, No. 4, p. 444-452, 2007/04
  • New insights into renal transport of urate, Naohiko Anzai,Yoshikatsu Kanai,Hitoshi Endou, CURRENT OPINION IN RHEUMATOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 19, No. 2, p. 151-157, 2007/03
  • Protein characterization of Na+-independent system L amino acid transporter 3 in mice - A potential role in supply of branched-chain amino acids under nutrient starvation, Daisuke Fukuhara,Yoshikatsu Kanai,Arthit Chairoungdua,Ellappan Babu,Fumio Bessho,Toshio Kawano,Yoshihiro Akimoto,Hitoshi Endou,Kunimasa Yan, AMERICAN JOURNAL OF PATHOLOGY, AMER SOC INVESTIGATIVE PATHOLOGY, INC, Vol. 170, No. 3, p. 888-898, 2007/03
  • L-type amino acid transporter-1 expressed in human astrocytomas, U343MGa, Shinji Asano,Megumi Kameyama,Ayako Oura,Anna Morisato,Hideki Sakai,Yoshiaki Tabuchi,Arthit Chairoungdua,Hitoshi Endou,Yoshikatsu Kanai, BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, Vol. 30, No. 3, p. 415-422, 2007/03
  • Metabolomic analysis of the knockout mice of a novel organic anion transporter OATN1: evaluation of the function and the potential roles as a therapeutic target, Xin He,Taku Hirata,Babu Ellappan,Naohiko Anzai,Takamasa Ishikawa,Tomoyoshi Soga,Hitoshi Entou,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, No. Supplement 1, p. 51P-51P, 2007
  • Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E-2 transport pathway, Sirinun Nilwarangkoon,Naohiko Anzai,Katsuko Shiraya,Erkang Yu,Rafiqul Islam,Seok Ho Cha,Maristela Lika Onozato,Daisaku Miura,Promsuk Jutabha,Akihiro Tojo,Yoshikatsu Kanai,Hitoshi Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, No. 1, p. 48-55, 2007/01
  • Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis, Shin Wakui,Kiyofumi Yokoo,Tomoko Muto,Yoshihiko Suzuki,Hiroyuki Takahashi,Masakuni Furusato,Hiroshi Hano,Hitoshi Endou,Yoshikatsu Kanai, LABORATORY INVESTIGATION, NATURE PUBLISHING GROUP, Vol. 86, No. 11, p. 1172-1184, 2006/11
  • Expression of amino acid transporter LATI and 4F2hc in the healing process after the implantation of a tooth ash and plaster of Paris mixture, Su-Gwan Kim,Young-Chae Ahn,Jung-Hoon Yoon,Hak-Kyun Kim,Sun-Sik Park,Sang-Gun Ahn,Hitoshi Endou,Yoshikatsu Kanai,Joo-Cheol Park,Do Kyung Kim, IN VIVO, INT INST ANTICANCER RESEARCH, Vol. 20, No. 5, p. 591-597, 2006/09
  • L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors, H Nawashiro,N Otani,N Shinomiya,S Fukui,H Ooigawa,K Shima,H Matsuo,Y Kanai,H Endou, INTERNATIONAL JOURNAL OF CANCER, WILEY-LISS, Vol. 119, No. 3, p. 484-492, 2006/08
  • Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3, Anabel Brandoni,Naohiko Anzai,Yoshikatsu Kanai,Hitoshi Endou,Adriana Monica Torres, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, ELSEVIER SCIENCE BV, Vol. 1762, No. 7, p. 673-682, 2006/07
  • Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3., Brandoni A,Anzai N,Kanai Y,Endou H,Torres AM, Biochimica et biophysica acta, Vol. 1762, No. 7, p. 673-682, 2006/07
  • The RNA interference of amino acid transporter LAT1 inhibits the growth of KB human oral cancer cells, Chang-Hyun Kim,Kyung Jin Park,Jung Rim Park,Yoshikatsu Kanai,Hitoshi Endou,Joo-Cheol Park,Do Kyung Kim, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 26, No. 4B, p. 2943-2948, 2006/07
  • The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity, R. Noshiro,N. Anzai,T. Sakata,H. Miyazaki,T. Terada,H. J. Shin,X. He,D. Miura,K. Inui,Y. Kanai,H. Endou, KIDNEY INTERNATIONAL, NATURE PUBLISHING GROUP, Vol. 70, No. 2, p. 275-282, 2006/07
  • Differential expression and functional characterization of system L amino acid transporters in human normal osteoblast cells and osteogenic sarcoma cells, SG Kim,HH Kim,HK Kim,CH Kim,HS Chun,Y Kanai,H Endou,DK Kim, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 26, No. 3A, p. 1989-1996, 2006/05
  • A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter, Y Shigeta,Y Kanai,A Chairoungdua,N Ahmed,S Sakamoto,H Matsuo,DK Kim,M Fujimura,N Anzai,K Mizoguchi,T Ueda,K Akakura,T Ichikawa,H Ito,H Endou, KIDNEY INTERNATIONAL, NATURE PUBLISHING GROUP, Vol. 69, No. 7, p. 1198-1206, 2006/04
  • Prenatal 3,3 ',4,4 ',5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1, 1B1, and AhR by 7,12-dimethylbenz[a]anthracene, S Wakui,K Yokoo,H Takahashi,T Muto,Y Suzuki,Y Kanai,H Hano,M Furusato,H Endou, TOXICOLOGY AND APPLIED PHARMACOLOGY, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 210, No. 3, p. 200-211, 2006/02
  • LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung, K Nakanishi,H Matsuo,Y Kanai,H Endou,S Hiroi,S Tominaga,M Mukai,E Ikeda,Y Ozeki,S Aida,T Kawai, VIRCHOWS ARCHIV, SPRINGER, Vol. 448, No. 2, p. 142-150, 2006/02
  • [Molecular mechanism in biological transport in the kidney: Organic cation/anion transporters]., Kanai Y, Nihon rinsho. Japanese journal of clinical medicine, Vol. 64 Suppl 2, p. 169-175, 2006/02
  • Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area, K Tsuji,K Yamauchi,M Yang,P Jiang,M Bouvet,H Endo,Y Kanai,K Yamashita,AR Moossa,RM Hoffman, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 66, No. 1, p. 303-306, 2006/01
  • Organic anion transporter family: Current knowledge, N Anzai,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, No. 5, p. 411-426, 2006
  • Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins, H Miyazaki,N Anzai,S Ekaratanawong,T Sakata,HJ Shin,P Jutabha,T Hirata,He, X,H Nonoguchi,K Tomita,Y Kanai,H Endou, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 16, No. 12, p. 3498-3506, 2005/12
  • High expression of L-type amino acid transporter 1 in infiltrating glioma cells, Hiroshi Nawashiro,Naoki Otani,Youichi Uozumi,Hidetoshi Ooigawa,Terushige Toyooka,Takamoto Suzuki,Hiroshi Katoh,Nobusuke Tsuzuki,Akira Ohnuki,Katsuji Shima,Nariyoshi Shinomiya,Hirotaka Matsuo,Yoshikatsu Kanai, Brain Tumor Pathology, Vol. 22, No. 2, p. 89-91, 2005/12
  • Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules, N Anzai,P Jutabha,A Enomoto,H Yokoyama,H Nonoguchi,T Hirata,K Shiraya,He, X,SH Cha,M Takeda,H Miyazaki,T Sakata,K Tomita,T Igarashi,Y Kanai,N Anzai, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 315, No. 2, p. 534-544, 2005/11
  • Integrated physiology of proximal tubular organic anion transport, N Anzai,P Jutabha,Y Kanai,H Endou, CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 14, No. 5, p. 472-479, 2005/09
  • CYP1 and AhR expression in 7,12-dimethylbenz[a] anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3,4,4 ',5-pentachlorobiphenyl, S Wakui,K Yokoo,H Takahashi,T Muto,Y Suzuki,Y Kanai,H Hano,M Furusato,H Endou, TOXICOLOGY, ELSEVIER IRELAND LTD, Vol. 211, No. 3, p. 231-241, 2005/08
  • Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells, JH Yoon,IJ Kim,F Kim,HJ Kim,MJ Jeong,SG Ahn,SA Kim,CH Lee,BK Choi,JK Kim,KY Jung,S Lee,Y Kanai,H Endou,DK Kim, CANCER LETTERS, ELSEVIER IRELAND LTD, Vol. 222, No. 2, p. 237-245, 2005/05
  • Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule, SY Park,JK Kim,IJ Kim,BK Choi,KY Jung,S Lee,KJ Park,A Chairoungdua,Y Kanai,H Endou,DK Kim, ARCHIVES OF PHARMACAL RESEARCH, PHARMACEUTICAL SOCIETY KOREA, Vol. 28, No. 4, p. 421-432, 2005/04
  • System L-amino acid transporters are differently expressed in rat astrocyte and C6 glioma cells, DK Kim,IJ Kim,S Hwang,JH Kook,MC Lee,BA Shin,CS Bae,JH Yoon,SG Ahn,SA Kim,Y Kanai,H Endou,JK Kim, NEUROSCIENCE RESEARCH, ELSEVIER SCI IRELAND LTD, Vol. 50, No. 4, p. 437-446, 2004/12
  • The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus, N Anzai,H Miyazaki,R Noshiro,S Khamdang,A Chairoungdua,HJ Shin,A Enomoto,S Sakamoto,T Hirata,K Tomita,Y Kanai,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 279, No. 44, p. 45942-45950, 2004/10
  • Mutations in SLC6A19, encoding B(0)AT1, cause Hartnup disorder, R Kleta,E Romeo,Z Ristic,T Ohura,C Stuart,M Arcos-Burgos,MH Dave,CA Wagner,SRM Camargo,S Inoue,N Matsuura,A Helip-Wooley,D Bockenhauer,R Warth,Bernardini, I,G Visser,T Eggermann,P Lee,A Chairoungdua,P Jutabha,E Babu,S Nilwarangkoon,N Anzai,Y Kanai,F Verrey,WA Gahl,A Koizumi, NATURE GENETICS, NATURE PUBLISHING GROUP, Vol. 36, No. 9, p. 999-1002, 2004/09
  • Lysophosphatidylcholine enhances cytokine production of endothelial cells via induction of L-type amino acid transporter 1 and cell surface antigen 4F2, W Takabe,Y Kanai,A Chairoungdua,N Shibata,S Toi,M Kobayashi,T Kodama,N Noguchi, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, No. 9, p. 1640-1645, 2004/09
  • Nicergoline enhances glutamate uptake via glutamate transporters in rat cortical synaptosomes, A Nishida,H Iwata,Y Kudo,T Kobayashi,Y Matsuoka,Y Kanai,H Endou, BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, Vol. 27, No. 6, p. 817-820, 2004/06
  • Measurement of glutamate uptake and reversed transport by rat synaptosome transporters, A Nishida,H Iwata,Y Kudo,T Kobayashi,Y Matsuoka,Y Kanai,H Endou, BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, Vol. 27, No. 6, p. 813-816, 2004/06
  • Expression of L-type amino acid transporter1 (LAT1) and 4F2 heavy chain (4F2hc) in oral squamous cell carcinoma and its precusor lesions, DK Kim,SG Ahn,JC Park,Y Kanai,H Endou,JH Yoon, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 24, No. 3A, p. 1671-1675, 2004/05
  • Preferential expression of L-type amino acid transporter 1 in ameloblasts during rat tooth development, JC Park,YB Kim,JH Yoon,HJ Kim,SM Kim,Y Kanai,H Endou,DK Kim, ANATOMIA HISTOLOGIA EMBRYOLOGIA-JOURNAL OF VETERINARY MEDICINE SERIES C, BLACKWELL VERLAG GMBH, Vol. 33, No. 2, p. 119-124, 2004/04
  • Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules, S Ekaratanawong,N Anzai,P Jutabha,H Miyazaki,R Noshiro,M Takeda,Y Kanai,S Sophasan,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, No. 3, p. 297-304, 2004/03
  • Expression and functional dcharacterization of the system L amino acid transporter in KB human oral epidermoid carcinoma cells, JH Yoon,YB Kim,MS Kim,JC Park,JK Kook,HM Jung,SG Kim,H Yoo,YM Ko,SH Lee,BY Kim,HS Chun,Y Kanai,H Endou,DK Kim, CANCER LETTERS, ELSEVIER IRELAND LTD, Vol. 205, No. 2, p. 215-226, 2004/03
  • High affinity D- and L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices, H Matsuo,Y Kanai,M Tokunaga,T Nakata,A Chairoungdua,H Ishimine,S Tsukada,H Ooigawa,H Nawashiro,Y Kobayashi,J Fukuda,H Endou, NEUROSCIENCE LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 358, No. 2, p. 123-126, 2004/03
  • The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects, Y Kanai,MA Hediger, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, SPRINGER-VERLAG, Vol. 447, No. 5, p. 469-479, 2004/02
  • The ancillary proteins of HATs: SLC3 family of amino acid transporters, M Palacin,Y Kanai, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, SPRINGER-VERLAG, Vol. 447, No. 5, p. 490-494, 2004/02
  • CATs and HATs: the SLC7 family of amino acid transporters, F Verrey,EI Closs,CA Wagner,M Palacin,H Endou,Y Kanai, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, SPRINGER-VERLAG, Vol. 447, No. 5, p. 532-542, 2004/02
  • Urate transporter: its regulation and clinical relevance, Y Kanai,N Anzai,M Hosoyamada,H Endou, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, PHARMACEUTICAL SOC JAPAN, Vol. 124, p. 25-28, 2004
  • Transport of Tc-99m-MAG3 via rat renal organic anion transporter 1, N Shikano,Y Kanai,K Kawai,N Ishikawa,H Endou, JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Vol. 45, No. 1, p. 80-85, 2004/01
  • Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions, T Sakata,N Anzai,HJ Shin,R Noshiro,T Hirata,H Yokoyama,Y Kanai,H Endou, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 313, No. 3, p. 789-793, 2004/01
  • The glutamate and neutral amino acid transporter family: physiological and pharmacological implications, Y Kanai,MA Hediger, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 479, No. 1-3, p. 237-247, 2003/10
  • Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters, E Babu,Y Kanai,A Chairoungdua,DK Kim,Y Iribe,S Tangtrongsup,P Jutabha,YW Li,N Ahmed,S Sakamoto,N Anzai,S Nagamori,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 278, No. 44, p. 43838-43845, 2003/10
  • [Urate transporter and renal hypouricemia]., Enomoto A,Niwa T,Kanai Y,Endou H, Rinsho byori. The Japanese journal of clinical pathology, Vol. 51, No. 9, p. 892-897, 2003/09
  • Sequential increases in 4F2hc expression during DMBA-induced hamster buccal pouch carcinogenesis, JH Yoon,YB Kim,Y Kanai,H Endou,DK Kim, ANTICANCER RESEARCH, INT INST ANTICANCER RESEARCH, Vol. 23, No. 5A, p. 3877-3881, 2003/09
  • Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule, P Jutabha,Y Kanai,M Hosoyamada,A Chairoungdua,DK Kim,Y Iribe,E Babu,JY Kim,N Anzai,Chatsudthipong, V,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 278, No. 30, p. 27930-27938, 2003/07
  • Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity, Yoshikatsu Kanai,Hitoshi Endou, Journal of Toxicological Sciences, Vol. 28, No. 1, p. 1-17, 2003/02
  • Isoform selectivity of 3-I-125-iodo-alpha-methyl-L-tyrosine membrane transport in human L-type amino acid transporters, N Shikano,Y Kanai,K Kawai,J Inatomi,DK Kim,N Ishikawa,H Endou, JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Vol. 44, No. 2, p. 244-246, 2003/02
  • Time Course of Expression of 7,12-Dimethylbenz[a]anthracene-induced CYP1A1 and CYP1B1 mRNA and Protein in Rat Liver, Tomoko Muto,Yoshikatsu Kanai,Hitoshi Endou,Takao Watanabe,Mitsuyoshi Moto,Miwa Okamura,Youko Kashida,Kunitoshi Mitsumori, Journal of Toxicologic Pathology, Vol. 16, No. 4, p. 287-290, 2003
  • Initial changes of hepatic glycogen granules and glycogen phosphorylase a after exposure to 7,12-dimethylbenz[a]anthracene in rats., J. Toxicol. Pathol., Vol. 16, p. 153-160, 2003
  • Characterization of 3-[I-125]iodo-alpha-methyl-L-tyro sine transport via human L-type amino acid transporter 1, N Shikano,Y Kanai,K Kawai,N Ishikawa,H Endou, NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER SCIENCE INC, Vol. 30, No. 1, p. 31-37, 2003/01
  • M6a acts as a nerve growth factor-gated Ca2+ channel in neuronal differentiation, S Mukobata,T Hibino,A Sugiyama,Y Urano,A Inatomi,Y Kanai,H Endo,F Tashiro, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 297, No. 4, p. 722-728, 2002/10
  • Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells, D Kim,Y Kanai,HW Choi,S Tangtrongsup,A Chairoungdua,E Babu,K Tachampa,N Anzai,Y Iribe,H Endou, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ELSEVIER SCIENCE BV, Vol. 1565, No. 1, p. 112-122, 2002/09
  • Molecular identification of a novel carnitine transporter specific to human testis - Insights into the mechanism of carnitine recognition, A Enomoto,MF Wempe,H Tsuchida,HJ Shin,SH Cha,N Anzai,A Goto,A Sakamoto,T Niwa,Y Kanai,MW Anders,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 39, p. 36262-36271, 2002/09
  • [Molecular mechanisms of glucose transport in renal proximal tubules]., Kanai Y, Nihon rinsho. Japanese journal of clinical medicine, Vol. 60 Suppl 7, p. 141-150, 2002/07
  • Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment, KI Hosoya,M Tomi,S Ohtsuki,H Takanaga,S Saeki,Y Kanai,H Endou,M Naito,T Tsuruo,T Terasaki, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 302, No. 1, p. 225-231, 2002/07
  • Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains, H Matsuo,Y Kanai,JY Kim,A Chairoungdua,DK Kim,J Inatomi,Y Shigeta,H Ishimine,S Chaekuntode,K Tachampa,HW Choi,E Babu,J Fukuda,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 23, p. 21017-21026, 2002/06
  • Molecular identification of a renal urate-anion exchanger that regulates blood urate levels, A Enomoto,H Kimura,A Chairoungdua,Y Shigeta,P Jutabha,SH Cha,M Hosoyamada,M Takeda,T Sekine,T Igarashi,H Matsuo,Y Kikuchi,T Oda,K Ichida,T Hosoya,K Shimokata,T Niwa,Y Kanai,H Endou, NATURE, NATURE PUBLISHING GROUP, Vol. 417, No. 6887, p. 447-452, 2002/05
  • Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): Insights into the mechanisms of substrate recognition, H Uchino,Y Kanai,DK Kim,MF Wempe,A Chairoungdua,E Morimoto,MW Anders,H Endou, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 61, No. 4, p. 729-737, 2002/04
  • The role of CD98 in astrocytic neoplasms, Hiroshi Nawashiro,Naoki Otani,Nariyoshi Shinomiya,Shinji Fukui,Namiko Nomura,Akiko Yano,Katsuji Shima,Hirotaka Matsuo,Yoshikatsu Kanai, Human cell: official journal of Human Cell Research Society, Vol. 15, No. 1, p. 25-31, 2002
  • The human T-type amino acid transporter-1: Characterization, gene organization, and chromosomal location, DK Kim,Y Kanai,H Matsuo,JY Kim,A Chairoungdua,Y Kobayashi,A Enomoto,SH Cha,T Goya,H Endou, GENOMICS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 79, No. 1, p. 95-103, 2002/01
  • Heterodimeric amino acid transporters: Molecular biology and pathological and pharmacological relevance, Y Kanai,H Endou, CURRENT DRUG METABOLISM, BENTHAM SCIENCE PUBL LTD, Vol. 2, No. 4, p. 339-354, 2001/12
  • Expression of l-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models, H Ohkame,H Masuda,Y Ishii,Y Kanai, JOURNAL OF SURGICAL ONCOLOGY, WILEY-LISS, Vol. 78, No. 4, p. 265-271, 2001/12
  • Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain, A Chairoungdua,Y Kanai,H Matsuo,J Inatomi,DK Kim,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 276, No. 52, p. 49390-49399, 2001/12
  • Transient upregulation of the glial glutamate transporter GLAST in response to fibroblast growth factor, insulin-like growth factor and epidermal growth factor in cultured astrocytes, K Suzuki,Y Ikegaya,S Matsuura,Y Kanai,H Endou,N Matsuki, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 114, No. 20, p. 3717-3725, 2001/10
  • Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines, O Yanagida,Y Kanai,A Chairoungdua,DK Kim,H Segawa,T Nii,SH Cha,H Matsuo,J Fukushima,Y Fukasawa,Y Tani,Y Taketani,H Uchino,JY Kim,J Inatomi,Okayasu, I,K Miyamoto,E Takeda,T Goya,H Endou, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ELSEVIER SCIENCE BV, Vol. 1514, No. 2, p. 291-302, 2001/10
  • Molecular events involved in up-regulating human Na+-independent neutral amino acid transporter LAT1 during T-cell activation, T Nii,H Segawa,Y Taketani,Y Tani,M Ohkido,S Kishida,M Ito,H Endou,Y Kanai,E Takeda,K Miyamoto, BIOCHEMICAL JOURNAL, PORTLAND PRESS, Vol. 358, No. Pt 3, p. 693-704, 2001/09
  • Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells, JY Kim,Y Kanai,A Chairoungdua,SH Cha,H Matsuo,DK Kim,J Inatomi,H Sawa,Y Ida,H Endou, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ELSEVIER SCIENCE BV, Vol. 1512, No. 2, p. 335-344, 2001/06
  • Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney, SH Cha,T Sekine,J Fukushima,Y Kanai,Y Kobayashi,T Goya,H Endou, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 59, No. 5, p. 1277-1286, 2001/05
  • Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters, DK Kim,Y Kanai,A Chairoungdua,H Matsuo,SH Cha,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 276, No. 20, p. 17221-17228, 2001/05
  • Human cystinuria-related transporter: Localization and functional characterization, K Mizoguchi,SH Cha,A Chairoungdua,DK Kim,Y Shigeta,H Matsuo,J Fukushima,Y Awa,K Akakura,T Goya,H Ito,H Endou,Y Kanai, KIDNEY INTERNATIONAL, BLACKWELL SCIENCE INC, Vol. 59, No. 5, p. 1821-1833, 2001/05
  • A new member of the HCO3- transporter superfamily is an apical anion exchanger of beta-intercalated cells in the kidney, H Tsuganezawa,K Kobayashi,M Iyori,T Araki,A Koizumi,SI Watanabe,A Kaneko,T Fukao,T Monkawa,T Yoshida,DK Kim,Y Kanai,H Endou,M Hayashi,T Saruta, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 276, No. 11, p. 8180-8189, 2001/03
  • Expression of L-type amino acid transporter 1 in a rat model of liver metastasis: Positive correlation with tumor size, S Tamai,H Masuda,Y Ishii,S Suzuki,Y Kanai,H Endou, CANCER DETECTION AND PREVENTION, JONES AND BARTLETT PUBLISHERS, Vol. 25, No. 5, p. 439-445, 2001
  • Expression of a system L neutral amino acid transporter at the blood-brain barrier, Hirotaka Matsuo,Shingo Tsukada,Takahiro Nakata,Arthit Chairoungdua,Do Kyung Kim,Seok Ho Cha,Jun Inatomi,Hiroshi Yorifuji,Jun Fukuda,Hitoshi Endou,Yoshikatsu Kanai, NeuroReport, Lippincott Williams and Wilkins, Vol. 11, No. 16, p. 3507-3511, 2000/11/09
  • The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier, T Kageyama,M Nakamura,A Matsuo,Y Yamasaki,Y Takakura,M Hashida,Y Kanai,M Naito,T Tsuruo,N Minato,S Shimohama, BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 879, No. 1-2, p. 115-121, 2000/10
  • Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs, S Wada,M Tsuda,T Sekine,SH Cha,M Kimura,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 294, No. 3, p. 844-849, 2000/09
  • Transport properties of a system y(+)L neutral and basic amino acid transporter - Insights into the mechanisms of substrate recognition, Y Kanai,Y Fukasawa,SH Cha,H Segawa,A Chairoungdua,DK Kim,H Matsuo,JY Kim,K Miyamoto,E Takeda,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 275, No. 27, p. 20787-20793, 2000/07
  • Involvement of rBAT in Na+-dependent and -independent transport of the neurotransmitter candidate L-DOPA in Xenopus laevis oocytes injected with rabbit small intestinal epithelium poly A(+) RNA, H Ishii,Y Sasaki,Y Goshima,Y Kanai,H Endou,D Ayusawa,H Ono,T Miyamae,Y Misu, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ELSEVIER SCIENCE BV, Vol. 1466, No. 1-2, p. 61-70, 2000/06
  • Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports D-serine with high affinity, J Nakauchi,H Matsuo,DK Kim,A Goto,A Chairoungdua,SH Cha,J Inatomi,Y Shiokawa,K Yamaguchi,Saito, I,H Endou,Y Kanai, NEUROSCIENCE LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 287, No. 3, p. 231-235, 2000/06
  • Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney, N Nakajima,T Sekine,SH Cha,A Tojo,M Hosoyamada,Y Kanai,K Yan,S Awa,H Endou, KIDNEY INTERNATIONAL, BLACKWELL SCIENCE INC, Vol. 57, No. 4, p. 1608-1616, 2000/04
  • Identification and characterization of a Na+-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids, Y Fukasawa,H Segawa,JY Kim,A Chairoungdua,DK Kim,H Matsuo,SH Cha,H Endou,Y Kanai, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 275, No. 13, p. 9690-9698, 2000/03
  • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta, SH Cha,T Sekine,H Kusuhara,E Yu,JY Kim,DK Kim,Y Sugiyama,Y Kanai,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 275, No. 6, p. 4507-4512, 2000/02
  • Identification and characterization of the high-affinity choline transporter, T Okuda,T Haga,Y Kanai,H Endou,T Ishihara,Katsura, I, NATURE NEUROSCIENCE, NATURE PUBLISHING GROUP, Vol. 3, No. 2, p. 120-125, 2000/02
  • Molecular cloning and characterization of multispecific organic anion transporter 4,OAT4., SH Cha,T Sekine,H Kusuhara,Y Sugiyama,Y Kanai,H Endou, CONTROL AND DISEASES OF SODIUM DEPENDENT TRANSPORT PROTEINS AND ION CHANNELS, ELSEVIER SCIENCE BV, Vol. 1208, p. 331-334, 2000
  • The family of amino acid transporters associated with type II membrane glycoproteins: the roles in epithelial transport and cellular nutrition., Y Kanai,H Segawa,A Chairoungdua,JY Kim,DK Kim,H Endou, CONTROL AND DISEASES OF SODIUM DEPENDENT TRANSPORT PROTEINS AND ION CHANNELS, ELSEVIER SCIENCE BV, Vol. 1208, p. 311-314, 2000
  • Amino acid transporters: molecular structure and physiological roles, Y Kanai,H Segawa,A Chairoungdua,JY Kim,DK Kim,H Matsuo,SH Cha,H Endou, NEPHROLOGY DIALYSIS TRANSPLANTATION, OXFORD UNIV PRESS, Vol. 15, No. Suppl 6, p. 9-10, 2000
  • Mouse Asc-1 (asc-type amino acid transporter 1) maps to chromosome 7, region B1-B5, H Matsuo,A Chairoungdua,DK Kim,SH Cha,J Fukuda,H Endou,Y Kanai, CHROMOSOME RESEARCH, KLUWER ACADEMIC PUBL, Vol. 8, No. 5, p. 456-456, 2000
  • Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity, M Takeda,A Tojo,T Sekine,R Hosoyamada,Y Kanai,H Endou, KIDNEY INTERNATIONAL, BLACKWELL SCIENCE INC, Vol. 56, No. 6, p. 2128-2136, 1999/12
  • Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities, T Igarashi,J Inatomi,T Sekine,SH Cha,Y Kanai,M Kunimi,K Tsukamoto,H Satoh,M Shimadzu,F Tozawa,T Mori,M Shiobara,G Seki,H Endou, NATURE GENETICS, NATURE AMERICA INC, Vol. 23, No. 3, p. 264-266, 1999/11
  • Identification of an amino acid transporter associated with the cystinuria-related type II membrane glycoprotein, A Chairoungdua,H Segawa,JY Kim,K Miyamoto,H Haga,Y Fukui,K Mizoguchi,H Ito,E Takeda,H Endou,Y Kanai, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 274, No. 41, p. 28845-28848, 1999/10
  • T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes, A Oku,K Ueta,K Arakawa,T Ishihara,M Nawano,Y Kuronuma,M Matsumoto,A Saito,K Tsujihara,M Anai,T Asano,Y Kanai,H Endou, DIABETES, AMER DIABETES ASSOC, Vol. 48, No. 9, p. 1794-1800, 1999/09
  • The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1, S Jariyawat,T Sekine,M Takeda,N Apiwattanakul,Y Kanai,S Sophasan,H Endou, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 290, No. 2, p. 672-677, 1999/08
  • Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity, H Segawa,Y Fukasawa,K Miyamoto,E Takeda,H Endou,Y Kanai, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 274, No. 28, p. 19745-19751, 1999/07
  • Transport of ochratoxin A by renal multispecific organic anion transporter 1, M Tsuda,T Sekine,M Takeda,SH Cha,Y Kanai,M Kimura,H Endou, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 289, No. 3, p. 1301-1305, 1999/06
  • Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes, N Apiwattanakul,T Sekine,A Chairoungdua,Y Kanai,N Nakajima,S Sophasan,H Endou, MOLECULAR PHARMACOLOGY, AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, Vol. 55, No. 5, p. 847-854, 1999/05
  • Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain, H Kusuhara,T Sekine,N Utsunomiya-Tate,M Tsuda,R Kojima,SH Cha,Y Sugiyama,Y Kanai,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 274, No. 19, p. 13675-13680, 1999/05
  • Immunohistochemical localization of multispecific renal organic anion transporter 1 in rat kidney, A Tojo,T Sekine,N Nakajima,M Hosoyamada,Y Kanai,K Kimura,H Endou, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 10, No. 3, p. 464-471, 1999/03
  • Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney, Makoto Hosoyamada,Takashi Sekine,Yoshikatsu Kanai,Hitoshi Endou, American Journal of Physiology - Renal Physiology, Vol. 276, No. 1, p. F122-F128, 1999/01
  • Amino acid transporter molecule as a drug target, Hitoshi Endou,Yoshikatsu Kanai, Folia Pharmacologica Japonica, Vol. 114, No. 1, 1999
  • Molecular biology of multispecific organic anion transporter family (OAT family), Takashi Sekine,Seok Ho Cha,Yoshikatsu Kanai,Hitoshi Endou, Clinical and Experimental Nephrology, Springer Japan, Vol. 3, No. 4, p. 237-243, 1999
  • Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney, M Hosoyamada,T Sekine,Y Kanai,H Endou, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 276, No. 1, p. F122-F128, 1999/01
  • Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine, T Sekine,H Kusuhara,N Utsunomiya-Tate,M Tsuda,Y Sugiyama,Y Kanai,H Endou, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 251, No. 2, p. 586-591, 1998/10
  • Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98), Y Kanai,H Segawa,K Miyamoto,H Uchino,E Takeda,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 273, No. 37, p. 23629-23632, 1998/09
  • Cloning, functional characterization, and localization of a rat renal Na(+)-dicarboxylate transporter, T Sekine,SH Cha,M Hosoyamada,Y Kanai,N Watanabe,Y Furuta,K Fukuda,T Igarashi,H Endou, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 275, No. 2, p. F298-F305, 1998/08
  • Identification of multispecific organic anion transporter 2 expressed predominantly in the liver, T Sekine,SH Cha,M Tsuda,N Apiwattanakul,N Nakajima,Y Kanai,H Endou, FEBS LETTERS, ELSEVIER SCIENCE BV, Vol. 429, No. 2, p. 179-182, 1998/06
  • Expression cloning using Xenopus laevis clocytes, Michael F. Romero,Yoshikatsu Kanai,Hironh Gunshin,Matthias A. Hediger, NEUROTRANSMITTER TRANSPORTERS, ELSEVIER ACADEMIC PRESS INC, Vol. 296, p. 17-52, 1998
  • A novel renal multispecific organic anion transporter(PAH transporter) : its structure and functional characteristics., Nova Acta Leopldina, Vol. 306, p. 119-126, 1998
  • Localization of the high-affinity glutamate transporter EAAC1 in rat kidney, Chairat Shayakul,Yoshikatsu Kanai,Wen-Sen Lee,Dennis Brown,Jeffrey D. Rothstein,Matthias A. Hediger, American Journal of Physiology - Renal Physiology, Vol. 273, No. 6, p. F1023-F1029, 1997/12
  • Localization of the high-affinity glutamate transporter EAAC1 in rat kidney, C Shayakul,Y Kanai,WS Lee,D Brown,JD Rothstein,MA Hediger, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 273, No. 6, p. F1023-F1029, 1997/12
  • Tissue specific variants of glutamate transporter GLT-1, N UtsunomiyaTate,H Endou,Y Kanai, FEBS LETTERS, ELSEVIER SCIENCE BV, Vol. 416, No. 3, p. 312-316, 1997/10
  • Family of neutral and acidic amino acid transporters: molecular biology, physiology and medical implications, Y Kanai, CURRENT OPINION IN CELL BIOLOGY, CURRENT BIOLOGY LTD, Vol. 9, No. 4, p. 565-572, 1997/08
  • Expression cloning and characterization of a novel multispecific organic anion transporter, T Sekine,N Watanabe,M Hosoyamada,Y Kanai,H Endou, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 272, No. 30, p. 18526-18529, 1997/07
  • A novel Na+-dependent amino acid transporter with a high affinity to glutamine, H Endou,Y Kanai,N UtsunomiyaTate,M Hosoyamada, NUTRITIONAL AND ACID-BASE ASPECTS OF AMINO ACID METABOLISM, KARGER, Vol. 121, p. 31-36, 1997
  • Substrate binding sites of glutamate transporters and structurally related neutral amino acid transporters, Yoshikatsu Kanai, Japanese Journal of Physiology, Vol. 47, No. 1, p. S55-S56, 1997
  • Structure, regulation and physiological roles of urea transporters, MA Hediger,CP Smith,GF You,WS Lee,Y Kanai,C Shayakul, KIDNEY INTERNATIONAL, BLACKWELL SCIENCE INC, Vol. 49, No. 6, p. 1615-1623, 1996/06
  • Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter, N UtsunomiyaTate,H Endou,Y Kanai, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 271, No. 25, p. 14883-14890, 1996/06
  • Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate, JD Rothstein,M DykesHoberg,CA Pardo,LA Bristol,L Jin,RW Kuncl,Y Kanai,MA Hediger,YF Wang,JP Schielke,DF Welty, NEURON, CELL PRESS, Vol. 16, No. 3, p. 675-686, 1996/03
  • MOLECULAR CHARACTERISTICS OF NA+-COUPLED GLUCOSE TRANSPORTERS IN ADULT AND EMBRYONIC RAT-KIDNEY, GF YOU,WS LEE,EJG BARROS,Y KANAI,TL HUO,S KHAWAJA,RG WELLS,SK NIGAM,MA HEDIGER, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 270, No. 49, p. 29365-29371, 1995/12
  • Neuronal high-affinity glutamate transport in the rat central nervous system, Y Kanai,PG Bhide,M DiFiglia,MA Hediger, NEUROREPORT, RAPID SCIENCE PUBLISHERS, Vol. 6, No. 17, p. 2357-2362, 1995/11
  • ELECTROGENIC PROPERTIES OF THE EPITHELIAL AND NEURONAL HIGH-AFFINITY GLUTAMATE TRANSPORTER, Y KANAI,S NUSSBERGER,MF ROMERO,WF BORON,SC HEBERT,MA HEDIGER, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 270, No. 28, p. 16561-16568, 1995/07
  • MAMMALIAN ION-COUPLED SOLUTE TRANSPORTERS, MA HEDIGER,Y KANAI,GF YON,S NUSSBERGER, JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, Vol. 482P, p. S7-S17, 1995/01
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  • THE NEURONAL AND EPITHELIAL HUMAN HIGH-AFFINITY GLUTAMATE TRANSPORTER - INSIGHTS INTO STRUCTURE AND MECHANISM OF TRANSPORT, Y KANAI,M STELZNER,S NUSSBERGER,S KHAWAJA,SC HEBERT,CP SMITH,MA HEDIGER, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 269, No. 32, p. 20599-20606, 1994/08
  • EXPRESSION OF A RABBIT RENAL ASCORBIC-ACID TRANSPORTER IN XENOPUS-LAEVIS OOCYTES, DL DYER,Y KANAI,MA HEDIGER,SA RUBIN,HM SAID, AMERICAN JOURNAL OF PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 267, No. 1, p. C301-C306, 1994/07
  • EXPRESSION CLONING AND CHARACTERIZATION OF THE GLUTAMATE TRANSPORTER IN NEURONS, MA HEDIGER,Y KANAI, RENAL PHYSIOLOGY AND BIOCHEMISTRY, KARGER, Vol. 17, No. 3-4, p. 161-164, 1994/05
  • EXPRESSION CLONING OF A MAMMALIAN PROTON-COUPLED OLIGOPEPTIDE TRANSPORTER, YJ FEI,Y KANAI,S NUSSBERGER,GANAPATHY, V,FH LEIBACH,MF ROMERO,SK SINGH,WF BORON,MA HEDIGER, NATURE, MACMILLAN MAGAZINES LTD, Vol. 368, No. 6471, p. 563-566, 1994/04
  • THE HIGH-AFFINITY NA+/GLUCOSE COTRANSPORTER - REEVALUATION OF FUNCTION AND DISTRIBUTION OF EXPRESSION, WS LEE,Y KANAI,RG WELLS,MA HEDIGER, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 269, No. 16, p. 12032-12039, 1994/04
  • ASSIGNMENT OF THE GENE CODING FOR THE HUMAN HIGH-AFFINITY GLUTAMATE TRANSPORTER EAAC1 TO 9P24 - POTENTIAL ROLE IN DICARBOXYLIC AMINOACIDURIA AND NEURODEGENERATIVE DISORDERS, CP SMITH,S WEREMOWICZ,Y KANAI,M STELZNER,CC MORTON,MA HEDIGER, GENOMICS, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 20, No. 2, p. 335-336, 1994/03
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  • A NEW FAMILY OF NEUROTRANSMITTER TRANSPORTERS - THE HIGH-AFFINITY GLUTAMATE TRANSPORTERS, Y KANAI,CP SMITH,MA HEDIGER, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 7, No. 15, p. 1450-1459, 1993/12
  • CLONING AND CHARACTERIZATION OF THE VASOPRESSIN-REGULATED UREA TRANSPORTER, GF YOU,CP SMITH,Y KANAI,WS LEE,M STELZNER,MA HEDIGER, NATURE, MACMILLAN MAGAZINES LTD, Vol. 365, No. 6449, p. 844-847, 1993/10
  • THE ELUSIVE TRANSPORTERS WITH A HIGH-AFFINITY FOR GLUTAMATE, Y KANAI,CP SMITH,MA HEDIGER, TRENDS IN NEUROSCIENCES, ELSEVIER SCI LTD, Vol. 16, No. 9, p. 365-370, 1993/09
  • IDENTIFICATION OF A NEW FAMILY OF PROTEINS INVOLVED IN AMINO-ACID-TRANSPORT, MA HEDIGER,Y KANAI,WS LEE,RG WELLS, MOLECULAR BIOLOGY AND FUNCTION OF CARRIER PROTEINS, ROCKEFELLER UNIV PRESS, Vol. 48, p. 301-314, 1993
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  • CLONING OF A HUMAN KIDNEY CDNA WITH SIMILARITY TO THE SODIUM-GLUCOSE COTRANSPORTER, RG WELLS,AM PAJOR,Y KANAI,E TURK,EM WRIGHT,MA HEDIGER, AMERICAN JOURNAL OF PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 263, No. 3, p. F459-F465, 1992/09
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  • SIMULTANEOUS DETERMINATION OF AMINO-ALPHA-CARBOLINES AND AMINO-GAMMA-CARBOLINES IN CIGARETTE-SMOKE CONDENSATE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, S MANABE,O WADA,Y KANAI, JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, ELSEVIER SCIENCE BV, Vol. 529, No. 1, p. 125-133, 1990/07
  • DETECTION OF CARCINOGENIC GLUTAMIC-ACID PYROLYSIS PRODUCTS IN CIGARETTE-SMOKE CONDENSATE, Y KANAI,O WADA,S MANABE, CARCINOGENESIS, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 11, No. 6, p. 1001-1003, 1990/06
  • ANTAGONISM OF GAMMA-AMINOBUTYRIC ACIDA RECEPTOR-MEDIATED RESPONSES BY AMINO-GAMMA-CARBOLINES, Y KANAI,O WADA,S MANABE, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, WILLIAMS & WILKINS, Vol. 252, No. 3, p. 1269-1276, 1990/03
  • SUPPRESSION OF GABA-INDUCED CHLORIDE CURRENT BY 3-AMINO-1-METHYL-5H-PYRIDO[4,3-B]INDOLE (TRP-P-2), Y KANAI,T AOSAKI,O WADA,S MANABE, EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, Vol. 166, No. 3, p. 553-556, 1989/08
  • EXPOSURE LEVEL MONITOR OF 3-AMINO-1,4-DIMETHYL-5H-PYRIDO[4,3-B]INDOLE, A DIETARY CARCINOGEN, IN RABBITS, S MANABE,Y KANAI,O WADA, ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, WILEY-LISS, Vol. 14, No. 1, p. 34-41, 1989
  • INVITRO AND INVIVO N-ACETYLATION OF CARCINOGENIC GLUTAMIC-ACID PYROLYSIS PRODUCTS IN HUMANS, Y KANAI,S MANABE,O WADA, CARCINOGENESIS, OXFORD UNIV PRESS UNITED KINGDOM, Vol. 9, No. 12, p. 2179-2184, 1988/12
  • CARCINOGENIC GLUTAMIC-ACID PYROLYSIS PRODUCT IN THE DIALYSATE OF UREMIC PATIENTS TREATED BY CONTINUOUS AMBULATORY PERITONEAL-DIALYSIS, H YANAGISAWA,S MANABE,Y KANAI,O WADA, CLINICAL NEPHROLOGY, DUSTRI-VERLAG DR KARL FEISTLE, Vol. 30, No. 2, p. 73-78, 1988/08
  • CARCINOGENIC TRYPTOPHAN PYROLYSIS PRODUCTS POTENT INHIBITORS OF TYPE-A MONOAMINE-OXIDASE AND THE PLATELET RESPONSE TO 5-HYDROXYTRYPTAMINE, S MANABE,Y KANAI,S ISHIKAWA,O WADA, JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY, WALTER DE GRUYTER & CO, Vol. 26, No. 5, p. 265-270, 1988/05
  • DETECTION OF N-ACETYL DERIVATIVE OF 2-AMINO-6-METHYLDIPYRIDO[1,2-A-3',2'-D]IMIDAZOLE (GLU-P-1) IN GLU-P-1-INJECTED RATS, Y KANAI,S MANABE,O WADA, MUTATION RESEARCH, ELSEVIER SCIENCE BV, Vol. 207, No. 2, p. 63-67, 1988/02
  • Carcinogenic Tryptophan Pyrolysis Products Potent Inhibitors of Type A Monoamine Oxidase and the Platelet Response to 5-Hydroxytryptamine, Shigeo Manabe,Yoshikatsu Kanai,Shinsuke Ishikawa,Osamu Wada, Clinical Chemistry and Laboratory Medicine, Vol. 26, No. 5, p. 265-270, 1988
  • Detection of N-acetyl derivative of 2-amino-6-methyldipyrido[1,2-α: 3′,2′-d]imidazole (Glu-P-1) in Glu-P-1-injected rats, Yoshikatsu Kanai,Shigeo Manabe,Osamu Wada, Mutation Research Letters, Vol. 207, No. 2, p. 63-67, 1988
  • PRESENCE OF CARCINOGENIC GLUTAMIC-ACID PYROLYSIS PRODUCTS IN HUMAN CATARACTOUS LENS, S MANABE,H YANAGISAWA,Y KANAI,O WADA, OPHTHALMIC RESEARCH, KARGER, Vol. 20, No. 1, p. 20-26, 1988/01
  • DETECTION OF CARCINOGENIC GLUTAMIC-ACID PYROLYSIS PRODUCTS IN WORCESTERSHIRE SAUCE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, S MANABE,Y KANAI,H YANAGISAWA,K TOHYAMA,S ISHIKAWA,Y KITAGAWA,O WADA, ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, WILEY-LISS, Vol. 11, No. 3, p. 379-388, 1988
  • ACCUMULATION OF 2-AMINO-6-METHYLDIPYRIDO[1,2-A-3',2'-D]IMIDAZOLE AND 2-AMINODIPYRIDO[1,2-A-3',2'-D]IMIDAZOLE, CARCINOGENIC GLUTAMIC-ACID PYROLYSIS PRODUCTS, IN PLASMA OF PATIENTS WITH UREMIA, S MANABE,H YANAGISAWA,S ISHIKAWA,Y KITAGAWA,Y KANAI,O WADA, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 47, No. 22, p. 6150-6155, 1987/11
  • INHIBITORY EFFECTS OF TRYPTOPHAN PYROLYSIS PRODUCTS ON HUMAN-PLATELET AGGREGATION THROUGH INHIBITION OF PROSTAGLANDIN ENDOPEROXIDE SYNTHETASE, S ISHIKAWA,S MANABE,H YANAGISAWA,Y KITAGAWA,Y KANAI,O WADA, FOOD AND CHEMICAL TOXICOLOGY, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 25, No. 11, p. 829-&, 1987/11
  • LONG-TERM EFFECTS OF 3-ACETYLPYRIDINE-INDUCED DESTRUCTION OF CEREBELLAR CLIMBING FIBERS ON PURKINJE-CELL INHIBITION OF VESTIBULOSPINAL TRACT CELLS OF THE RAT, L KARACHOT,M ITO,Y KANAI, EXPERIMENTAL BRAIN RESEARCH, SPRINGER VERLAG, Vol. 66, No. 2, p. 229-246, 1987

Misc.

  • 浸潤性乳癌におけるL型アミノ酸輸送体1(LAT1)の臨床病理学的および予後的意義(Clinicopathological and prognostic significance of L-type amino acid transporter 1(LAT1) in invasive breast cancer), 黒住 献,解良 恭一,松本 広志,横堀 武彦,金井 好克,黒住 昌史,古谷 未央,小山 徹也,藤井 孝明,調 憲, 日本癌治療学会学術集会抄録集, (一社)日本癌治療学会, Vol. 57回, p. IO5-4, 2019/10
  • がん細胞のアミノ酸トランスポーターを標的としたがん診断と治療の開発, Vol. 271, No. 1, p. 71-77, 2019/10
  • がん研究における女性研究者(第6回) がん細胞型アミノ酸トランスポーターを標的とした短寿命アルファ線核医学治療薬の開発(Women scientists in cancer research Investigation of novel drug for alpha-emitting nuclear medicine targeting to cancer specific amino acid transporter), 兼田 加珠子,真鍋 良幸,下山 敦史,樺山 一哉,金井 好克,豊嶋 厚史,深瀬 浩一,篠原 厚, 日本癌学会総会記事, 日本癌学会, Vol. 78回, p. SS-3, 2019/09
  • PEG結合リン脂質の細胞外表層pHイメージングへの応用 細胞膜アンカー型プローブ骨格としての可能性, Vol. 153, No. 6, p. 254-260, 2019/06
  • アミノ酸シグナルの解明からがん治療へ アミノ酸トランスポーター阻害によるがん代謝制御, Vol. 37, No. 4, p. 508-513, 2019/03
  • Establishment of novel targeted alpha-radionuclide medicine, Kaneda Kazuko,Fukuda Mitsuhiro,Kanai Yoshikatsu,Hatazawaj Jun,Nakano Takashi,Fukase Koichi,Shinohara Atsushi,Zhang Zijian,Shirakami Norifumi,Watabe Tadashi,Shimoyama Atsushi,Manabey Yoshiyuki,Kabayama Kazuya,Toyoshima Atsushi,Yoshimura Takashi, Proceedings for Annual Meeting of The Japanese Pharmacological Society, Japanese Pharmacological Society, Vol. 92, No. 0, p. 3-P-109, 2019
  • がん細胞型アミノ酸トランスポーターを標的とした新規核医学治療薬の開発(Investigation of novel drug for nuclear medicine targeting to cancer specific amino acid transporter, LAT1), 兼田 加珠子,張 子見,真鍋 良幸,下山 敦史,樺山 一哉,金井 好克,深瀬 浩一, 日本癌学会総会記事, 日本癌学会, Vol. 77回, p. 865-865, 2018/09
  • アミノ酸トランスポーターLAT1を標的とするα線がんミサイル療法の開発, Vol. 91回, p. [2P-272], 2018/09
  • LAT1阻害剤JPH203は、IGFBP-5を介して、膀胱癌細胞の増殖、浸潤、遊走能を阻害す(LAT1 inhibitor JPH203 inhibit cell proliferation, invasion, and migration through IGFBP-5), Vol. 77回, p. 1280-1280, 2018/09
  • SGLT2阻害薬の薬理作用, Vol. 46, No. 4, p. 297-304, 2018/04
  • DAMPsとしての尿酸, Vol. 264, No. 12, p. 1036-1040, 2018/03
  • Amino acid transporter chaperons its fusogenic partner: an essential role in placenta, and its implications for physiological and pathological cell fusion, Ryuichi Ohgaki,Yoshikatsu Kanai, Atlas of Science (http://atlasofscience.org/), 2018/01
  • 短寿命α線核種を用いた新規抗がん薬開発の検討, Vol. 2017年度, p. [2PT26-0899)], 2017/12
  • SGLT2の機能とSGLT2阻害薬の作用機序, No. 4860, p. 28-34, 2017/06
  • 胃癌におけるCD98発現の臨床病理学的な意義についての検討, 佐藤 泰輔,解良 恭一,高橋 研吾,高橋 憲史,金井 好克,浅尾 高行,堀口 淳,小山 徹也, 日本外科学会定期学術集会抄録集, (一社)日本外科学会, Vol. 117回, p. PS-172, 2017/04
  • Diagnostic usefulness of F-18-FAMT PET and L-type amino acid transporter 1 (LAT1) expression in oral squamous cell carcinoma, Nobusawa, Aiko,Kim, Mai,Kaira, Kyoichi,Miyashita, Go,Negishi, Akihide,Oriuchi, Noboru,Higuchi, Tetsuya,Tsushima, Yoshito,Kanai, Yoshikatsu,Yokoo, Satoshi,Oyama, Tetsunari, EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Vol. 40, No. 11, p. 1692-1700, 2017
  • Na+依存性糖トランスポーターSGLT群の概要と糖輸送メカニズム, Vol. 3, No. 1, p. 6-10, 2017/01
  • 総論 SGLT2阻害薬の作用メカニズムと多面的な薬理作用, Vol. 31, No. 12, p. 1232-1233, 2016/11
  • Na+/グルコーストランスポーターSGLT2, Vol. 4, No. 5, p. 411-419, 2016/11
  • トランスポーター阻害に基づく糖尿病創薬 SGLT2阻害薬, Vol. 31, No. 5, p. 450-461, 2016/11
  • 肥満脂肪組織におけるグルタミン酸上昇とその病態学的意義~in vivo代謝動態解析を用いて~, 長尾博文,西澤均,馬場健史,中山泰宗,永森收志,金井好克,喜多俊文,喜多俊文,田中紀實,福田士郎,前田法一,前田法一,船橋徹,船橋徹,福崎英一郎,下村伊一郎, 肥満研究, Vol. 22, No. Suppl., p. 227-227, 2016/09
  • SGLT2阻害薬 基礎的な立場からの有用性, Vol. 59, No. 9, p. 628-631, 2016/09
  • SGLT2阻害薬の尿酸低下作用, Vol. 43, No. 1, p. 66-72, 2016/07
  • Inhibition Kinetics, Sidedness of Action, and Transporter-mediated Uptake of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin: Implications for Its Pharmacodynamic and Pharmacokinetic Features, Ryuichi Ohgaki,Ling Wei,Kazunori Yamada,Taiki Hara,Chiaki Kuriyama,Suguru Okuda,Kiichiro Ueta,Laurent Leclercq,Rao Nvs Mamidi,Masaharu Shiotani,Shushi Nagamori,Yoshikatsu Kanai, DIABETES, AMER DIABETES ASSOC, Vol. 65, p. A299-A299, 2016/06
  • 肥満脂肪組織におけるin vivo代謝動態解析:グルタミン酸上昇とその病態学的意義, 長尾博文,西澤均,馬場健史,中山泰宗,永森收志,金井好克,喜多俊文,喜多俊文,田中紀實,前田法一,船橋徹,船橋徹,福崎英一郎,下村伊一郎, 日本内分泌学会雑誌, Vol. 92, No. 1, p. 201-201, 2016/04
  • トランスポーターSGLT2の同定とSGLT2阻害薬創製への道のり, Vol. 2, No. 2, p. 103-106, 2016/04
  • SGLT2阻害薬の特徴 基礎研究の観点から, Vol. 36, No. 2, p. 183-188, 2016/02
  • 肥満脂肪組織におけるin vivoメタボロミクス動態解析:グルタミン酸上昇とその病態学的意義, 長尾博文,西澤均,馬場健史,中山泰宗,永森收志,金井好克,喜多俊文,喜多俊文,田中紀實,福田士郎,前田法一,船橋徹,船橋徹,福崎英一郎,下村伊一郎, 糖尿病(Web), Vol. 59, No. Suppl, 2016
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Other ion channels, Stephen P. H. Alexander,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 5942-5955, 2015/12
  • THE CONCISE GUIDE TO PHARMACOLOGY 2015/16: Voltage-gated ion channels, Stephen P. H. Alexander,William A. Catterall,Eamonn Kelly,Neil Marrion,John A. Peters,Helen E. Benson,Elena Faccenda,Adam J. Pawson,Joanna L. Sharman,Christopher Southan,Jamie A. Davies,R. Aldrich,B. Attali,M. Back,N. M. Barnes,R. Bathgate,P. M. Beart,E. Becirovic,M. Biel,N. J. Birdsall,D. Boison,H. Brauner-Osborne,S. Broeer,C. Bryant,G. Burnstock,T. Burris,D. Cain,G. Calo,S. L. Chan,K. G. Chandy,N. Chiang,S. Christakos,A. Christopoulos,J. J. Chun,J. -J. Chung,D. E. Clapham,M. A. Connor,L. Coons,H. M. Cox,F. M. Dautzenberg,G. Dent,S. D. Douglas,M. L. Dubocovich,D. P. Edwards,R. Farndale,T. M. Fong,D. Forrest,C. J. Fowler,P. Fuller,R. R. Gainetdinov,M. A. Gershengorn,A. Goldin,S. A. N. Goldstein,S. L. Grimm,S. Grissmer,A. L. Gundlach,B. Hagenbuch,J. R. Hammond,J. C. Hancox,S. Hartig,R. L. Hauger,D. L. Hay,T. Hebert,A. N. Hollenberg,N. D. Holliday,D. Hoyer,A. P. Ijzerman,K. I. Inui,S. Ishii,K. A. Jacobson,L. Y. Jan,G. E. Jarvis,R. Jensen,A. Jetten,R. Jockers,L. K. Kaczmarek,Y. Kanai,H. S. Kang,S. Karnik,I. D. Kerr,K. S. Korach,C. A. Lange,D. Larhammar,F. Leeb-Lundberg,R. Leurs,S. J. Lolait,D. Macewan,J. J. Maguire,J. M. May,J. Mazella,C. A. McArdle,D. P. McDonnell,M. C. Michel,L. J. Miller,V. Mitolo,T. Monie,P. N. Monk,B. Mouillac,P. M. Murphy,J. -L. Nahon,J. Nerbonne,C. G. Nichols,X. Norel,R. Oakley,S. Offermanns,L. G. Palmer,M. A. Panaro,E. Perez-Reyes,R. G. Pertwee,J. W. Pike,J. P. Pin,S. Pintor,L. D. Plant,D. R. Poyner,E. R. Prossnitz,S. Pyne,D. Ren,J. K. Richer,P. Rondard,R. A. Ross,H. Sackin,R. Safi,M. C. Sanguinetti,C. A. Sartorius,D. L. Segaloff,F. M. Sladek,G. Stewart,L. A. Stoddart,J. Striessnig,R. J. Summers,Y. Takeda,M. Tetel,L. Toll,J. S. Trimmer,M. -J. Tsai,S. Y. Tsai,S. Tucker,T. B. Usdin,J. -P. Vilargada,M. Vore,D. T. Ward,S. G. Waxman,P. Webb,A. D. Wei,N. Weigel,G. B. Willars,C. Winrow,S. S. Wong,H. Wulff,R. D. Ye,M. Young,J. -M. Zajac, BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, Vol. 172, No. 24, p. 5904-5941, 2015/12
  • 疾患起因性変異ノックインマウスを用いた日本人型シスチン尿症変異の特性解析, Vol. 14, No. 2, p. 151-153, 2015/11
  • 肥満脂肪組織におけるグルタミン酸上昇とその病態学的意義~メタボロミクス解析より~, 長尾博文,西澤均,馬場健史,中山泰宗,永森收志,金井好克,喜多俊文,田中紀實,福田士郎,前田法一,船橋徹,福崎英一郎,下村伊一郎, 肥満研究, Vol. 21, No. Suppl., p. 153-153, 2015/09
  • 内耳の特殊体液の恒常性が立脚する膜輸送系の網羅的タンパク質解析, 上塚学,上塚学,緒方元気,永森收志,五十棲規嘉,吉田崇正,吉田崇正,任書晃,吉川欣晃,猪原秀典,金井好克,日比野浩, 応用薬理, 応用薬理研究会, Vol. 89, No. 1-2, p. 54-54, 2015/08/17
  • Evaluation of the amino acid transporter: comparison study between FBPA and BPA in vitro., Hayato Ikeda,Tadashi Watabe,Shushi Nagamori,Yoko Tanaka,Pattama Wiriyasermkul,Yasukazu Kanai,Sadahiro Naka,Eku Shimosegawa,Yoshikatsu Kanai,Jun Hatazawa, JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Vol. 56, No. 3, 2015/05
  • F-18-FBPA and F-18-FAMT dynamic PET profile: evaluation of usefulness in differentiating malignant tumors from inflammatory lesions., Masanao Aoki,Tadashi Watabe,Shushi Nagamori,Hayato Ikeda,Sadahiro Naka,Yasukazu Kanai,Kohei Hanaoka,Eku Shimosegawa,Yoshikatsu Kanai,Jun Hatazawa, JOURNAL OF NUCLEAR MEDICINE, SOC NUCLEAR MEDICINE INC, Vol. 56, No. 3, 2015/05
  • Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in tongue cancer., Kyoichi Kaira,Minoru Toyoda,Yasuhiro Ohshima,Noboru Oriuchi,Yoshikatsu Kanai,Tetsunari Oyama,Masanobu Yamada,Takayuki Asao,Kazuaki Chikamatsu, JOURNAL OF CLINICAL ONCOLOGY, AMER SOC CLINICAL ONCOLOGY, Vol. 33, No. 15, 2015/05
  • Proteomic analysis of the epithelial tissue that drives membrane transport systems in the cochlea of the inner ear, UETSUKA SATORU,UETSUKA SATORU,OGATA GENKI,NAGAMORI SYUSHI,IGARASHI NORIYOSHI,YOSHIDA TAKAMASA,YOSHIDA TAKAMASA,NIN FUMIAKI,KITAHARA TADASHI,KIKKAWA YOSHIAKI,INOHARA HIDENORI,KANAI YOSHIKATSU,HIBINO HIROSHI, J Physiol Sci, Vol. 65, No. Supplement 1, 2015
  • プロテオミクスを用いたトランスポーターの網羅的発現, Vol. 69, No. 1, p. 47-51, 2015/01
  • 糖輸送体, Vol. 33, No. 1, p. 8-14, 2015/01
  • SGLTの基礎と創薬展開, Vol. 2015, p. 26-34, 2015/01
  • 芳香族アミン誘導体の抗腫瘍効果の確立と非臨床POCの取得, Vol. 42, No. Suppl.XXXIII, p. 93-96, 2014/12
  • SGLT2阻害薬 薬理学の視点から, Vol. 42, No. 4, p. 138-146, 2014/12
  • 糖尿病のここがわからない!?(第15回) 尿糖排泄の分子メカニズムのここがわからない!?, Vol. 4, No. 4, p. 148-156, 2014/11
  • 新規糖尿病治療薬開発の現状 SGLT2阻害薬の基礎 作用機序を中心に, Vol. 6, No. 9, p. 27-33, 2014/10
  • 内耳の特殊体液の恒常性が立脚する上皮イオン輸送の分子構築の解析, 上塚学,緒方元気,永森收志,吉田崇正,任書晃,北原糺,猪原秀典,金井好克,日比野浩, Otol Jpn, Vol. 24, No. 4, 2014/09/16
  • SGLT2阻害薬 SGLTの基礎, Vol. 13, No. 2, p. 26-33, 2014/08
  • SGLT2阻害薬の開発の経緯、および作用機序, Vol. 1, No. 2, p. 6-11, 2014/08
  • SGLTの役割とSGLT2阻害薬のメカニズム, No. 97, p. 13-14, 2014/07
  • がんとアミノ酸トランスポーター, Vol. 86, No. 3, p. 338-343, 2014/06
  • 糖尿病の最新治療, KANAI Yoshikatsu, Vol. 5, No. 3, p. 118-124, 2014/05
  • Tissue microarrayを利用した乳癌のstem cell marker及びアミノ酸トランスポーター発現の検討, Vol. 22, 2014/04
  • 糖尿病治療に新しい発展をもたらしたSGLT2の発見, Vol. 10, No. 2, p. 16-18, 2014/04
  • 新たなSGLT2阻害薬に期待される作用とその効果 SGLT2阻害薬の基礎, Vol. 34, No. 4, p. 653-657, 2014/04
  • 腎臓をターゲットとした薬物治療トピックス SGLT2阻害薬, Vol. 3, No. 2, p. 79-86, 2014/04
  • Molecular identification of transporters and their application to molecular target drug discovery, Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 14P-14P, 2014
  • Effects of substrate elasticity on contractile properties of human induced pluripotent stem cell-derived cardiomyocytes, Miki Fujizuka,Junko Kurokawa,Hatsume Uno,Yuji Nakai,Shushi Nagamori,Yoshikatsu Kanai,Yasunari Kanda,Eriko Matsui,Tetsushi Furukawa, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 157P-157P, 2014
  • Functional Coupling of a Urate-Anion Exchanger URAT1 and Sodium-Dependent Anion Transporter SMCT2 on a PDZK1 Scaffold; Proposal of "Transportsome" for Urate-Transport, Shushi Nagamori,Pattama Wiriyasermkul,Yasuhiro Umemura,Noriyoshi Isozumi,Yumiko Nishinaka,Yoshikatsu Kanai, BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 106, No. 2, p. 368A-368A, 2014/01
  • Mechanisms of tumor cell uptake of 4-borono-phenylalanine, a B-10 carrier of boron neutron capture therapy, mediated by system L amino acid transporters, Printip Wongthai,Kohei Hagiwara,Yurika Miyoshi,Pattama Wiriyasermkul,Pornparn Kongpracha,Noriyoshi Isozumi,Ryuichi Ohgaki,Kenjiro Tadagaki,Kenji Hamase,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 97P-97P, 2014
  • Evaluation of amino acid transporter LAT1 as a molecular target of anti-tumor therapy by means of the combination of comprehensive proteomics and transport assay, Shushi Nagamori,Pattama Wiriyasermkul,Noriyoshi Isozumi,Pornparn Kongpracha,Ryuichi Ohgaki,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 130P-130P, 2014
  • Expression analysis of amino acid transporter LAT1 in mouse development, Tomohisa Katada,Masami Kanai-Azuma,Yoshikatsu Kanai,Hitoshi Endou,Hiroyuki Sakurai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 145P-145P, 2014
  • Development of PET diagnosis and therapeutic drugs for malignant tumors targeting amino acid transporters, Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 124, p. 30P-30P, 2014
  • 内耳の特殊体液の恒常性が立脚する上皮イオン輸送の分子構築の解析, 上塚学,緒方元気,永森收志,五十棲規嘉,吉田崇正,任書晃,北原糺,猪原秀典,金井好克,日比野浩, 日本薬理学会北部会プログラム・抄録集, Vol. 65th, 2014
  • 新たな作用機序の糖尿病治療薬としてのSGLT2阻害薬, Vol. 45, No. 1, p. 33-34, 2014/01
  • SGLT・レッスン SGLT2発見の歴史・経緯と腎臓の糖再吸収機構, Vol. 2, No. 3, p. 186-193, 2013/07
  • アミノ酸トランスポーターと疾患 シスチン尿症と悪性腫瘍を中心に, Vol. 245, No. 1, p. 43-49, 2013/04
  • 腎特異プロスタグランジン輸送体OAT‐PGノックアウトマウスの食塩応答性血圧変動の機序の解明, 金井好克,永森收志,大垣隆一,中込咲綾,PATTAMA Wiriyasermkul,西山俊, ソルト・サイエンス研究財団助成研究報告集 2 医学 食品科学編, Vol. 2011, p. 83-91, 2013/03
  • Na+依存性グルコーストランスポーター 基礎研究から次世代抗糖尿病薬開発まで, Vol. 74, No. 2, p. 300-306, 2013/02
  • BORONOPHENYLALANINE, A RATIONAL CARRIER FOR B-10 FOR BORON NEUTRON CAPTIVE THERAPY, IS TRANSPORTED BY BOTH LAT1 AND LAT2, Printip Wongthai,Pattama Wiriyasermkul,Yumiko Nishinaka,Ryuichi Ohgaki,Kenjiro Tadagaki,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 121, p. 69P-69P, 2013
  • Kinetic analysis of 3F-L-alpha-amethyltyrosine (FAMT) transport by L-type amino acid transporter 1, Ling Wei,Hideyuki Tominaga,Pattama Wiriyasermkul,Yumiko Nishinaka,Ryuichi Ohgaki,Kenjiro Tadagaki,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 121, p. 125P-125P, 2013
  • Cellular responses to LAT1-mediated leucine uptake are revealed by using an LAT1 inhibitor and comprehensive phosphoproteomics, Shushi Nagamori,Pattama Wiriyasermkul,Satoshi Serada,Masaki Matsumoto,Kenichi Nakayama,Tetsuji Naka,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 121, p. 119P-119P, 2013
  • トランスポートソーム その生理的意義と疾患, Vol. 2013, p. 17-24, 2013/01
  • 【先天代謝異常症候群(第2版)(下)-病因・病態研究、診断・治療の進歩-】膜輸送系の異常 膜輸送系の異常 概論, Vol. 別冊先天代謝異常症候群(下), p. 759-766, 2012/12
  • アミノ酸トランスポーターを標的とした癌デリバリー, Vol. 27, No. 5, p. 342-349, 2012/11
  • がん代謝と創薬研究 アミノ酸トランスポーターとがん代謝, Vol. 30, No. 15, p. 2494-2500, 2012/09
  • 悪性腫瘍の診断と治療の分子標的としてのトランスポーター, Vol. 31, No. 5, p. 567-571, 2012/04
  • アミノ酸トランスポーターと疾患 シスチン尿症と悪性腫瘍を中心に, Vol. 10, No. 2, p. 1-15, 2012/02
  • 日本人シスチン尿症解析 新規シスチン尿症分類の必要性について, Vol. 10, No. 2, p. 146-153, 2012/02
  • A C-terminus mutation of SLC7A9 amino acid transporter frequent in Japanese cystinuria patients retains substrate binding but diminishes the transport activity., Y. Kawamoto,S. Nagamori,P. Wiriyasermkul,Y. Kanai, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 23, 2012
  • Nicotine induces dendritic spine remodeling in cultured hippocampal neurons, Akira Oda,Kanato Yamagata,Ryuichi Ohgaki,Shushi Nagamori,Yoshikatsu Kanai,Hidekazu Tanaka, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 118P-118P, 2012
  • Establishment of a human-disease model mouse for Japanese-type cystinuria, Yasuharu Kawamoto,Shushi Nagamori,Pattama Wiriyasermkul,Kenichiro Iio,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 72P-72P, 2012
  • Comprehensive and comparative quantification of epithelial cell membrane transporters between wild type and diabetic model mice, Shushi Nagamori,Kazuaki Takafuji,Takashi Nishiyama,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 118, p. 253P-253P, 2012
  • 尿酸降下薬の分子標的 新規ヒト尿酸/有機酸トランスポーターURAT2の同定, Vol. 35, No. 1, p. 57-57, 2011/07
  • 痛風の主要病因遺伝子ABCG2の臨床遺伝学的解析, Vol. 35, No. 1, p. 96-96, 2011/07
  • 生体膜トランスポーター研究の現状と展望, Vol. 36, No. 4, p. 128-138, 2011/07
  • System L amino-acid transporter: a new target for anti-cancer treatments in human cholangiocarcinoma, Arthit Chairoungdua,Narumol Bhummaphan,Yoshikatsu Kanai, DRUG METABOLISM REVIEWS, INFORMA HEALTHCARE, Vol. 43, p. 88-89, 2011/05
  • 新規ヒト尿酸/有機酸トランスポーターURAT2の分子同定, Vol. 53, No. 3, p. 366-366, 2011/05
  • 開発中の次世代の治療薬 SGLT阻害薬, Vol. 28, No. 4, p. 111-117, 2011/04
  • L-型アミノ酸トランスポーター1(LAT1)による輸送と哺乳類ラパマイシン標的タンパク質(mTOR)活性化のためのロイシン誘導体の構造的必要性(The structural requirements of leucine derivatives to be transported by L-type amino acid transporter 1(LAT1) and to activate mammalian target of rapamycin(mTOR)), Wiriyasermkul Pattama,永森 收志,木村 徹,大垣 隆一,金井 好克, 日本薬理学雑誌, (公社)日本薬理学会, Vol. 137, No. 3, p. 31P-31P, 2011/03
  • トランスポーターとトランスポートソーム, No. 19, p. 23-34, 2011/03
  • メタボロミクスによるトランスポーター機能へのアプローチ メタボローム解析によるオーファントランスポーターの機能の探索, No. 19, p. 71-76, 2011/03
  • トランスポートソーム トランスポートソームの実体とその機能的意義, No. 19, p. 202-209, 2011/03
  • 尿酸降下薬の分子標的 新規ヒト尿酸/有機酸トランスポーターURAT2の同定, Vol. 44回, p. 52-52, 2011/02
  • 痛風の主要病因遺伝子ABCG2の臨床遺伝学的解析, Vol. 44回, p. 89-89, 2011/02
  • A novel human urate/anion exchanger URAT2 identified as a novel target of uricosuric agents, Promsuk Jutabha,Naohiko Anzai,Kenichiro Kitamura,Kimiyoshi Ichida,Ichiro Hisatome,Toru Kimura,Seiji Ueno,Yoshikatsu Kanai,Hitoshi Endou,Hiroyuki Sakurai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 90P-90P, 2011
  • Critical structural property of leucine to activate amino acid signaling via transporters, Pattama Wiriyasermkul,Shushi Nagamori,Toru Kimura,Ryuichi Ohgaki,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 68P-68P, 2011
  • Establishment of procedure for comprehensive mass spectrometric analysis of epithelial cell membrane transporters, Shushi Nagamori,Kazuaki Takafuji,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 115, p. 82P-82P, 2011
  • 痛風の主要病因遺伝子の探索と同定, Vol. 83回・33回, p. 4P-1131, 2010/12
  • 癌のアミノ酸トランスポーターと代謝制御, Vol. 30, No. 1, p. 41-46, 2010/12
  • 薬理学からみた脳卒中, Vol. 9, No. 4, p. 422-429, 2010/10
  • 痛風の主要病因遺伝子ABCG2の同定, Vol. 34, No. 1, p. 59-60, 2010/07
  • 尿酸トランスポーターUrat1セミノックインマウスにおける尿酸の体内動態, Vol. 34, No. 1, p. 68-68, 2010/07
  • 新たなNa調節系, Vol. 33, No. 1, p. 6-11, 2010/06
  • 尿酸輸送体過剰発現マウスを用いた尿酸輸送の解析, Vol. 52, No. 3, p. 293-293, 2010/05
  • ヒト有機アニオントランスポーター3発現細胞とラットを用いたセレコキシブ-メトトレキサート間相互作用, 前田 章光,鶴岡 秀一,牛島 健太郎,金井 好克,遠藤 仁,藤村 昭夫, 日本腎臓学会誌, (一社)日本腎臓学会, Vol. 52, No. 3, p. 341-341, 2010/05
  • 痛風の主要病因遺伝子ABCG2の同定, Vol. 43回, p. 80-80, 2010/02
  • 尿酸トランスポーターUrat1セミノックインマウスにおける尿酸の体内動態, Vol. 43回, p. 88-88, 2010/02
  • Transport kinetics of the amino acid PET ligand L-[3-F]-alpha-methyltyrosine, FAMT, by a cancer specific amino acid transporter, LAT1, Shushi Nagamori,Pattama Wiriyasermkul,Hideyuki Tominaga,Noboru Oriuchi,Kyoichi Kaira,Hidekazu Nakao,Takeru Kitashoji,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 120P-120P, 2010
  • The role of a novel kidney-specific prostaglandin transporter in the local prostaglandin clearance in renal cortex, Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 23P-23P, 2010
  • Dynamic roles of proteins in synaptic adherens junction, Hidekazu Tanaka,Kazuaki Takafuji,Hong Shi,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 238P-238P, 2010
  • The roles of a novel PG transporter in the local clearance and metabolism of PGE2 in renal cortex, Ryo Hatano,Mitsunobu Matsubara,Shushi Nagamori,Kazuaki Takafuji,Promchan Kanyarat,Wiryasermkul Pattama,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 66P-66P, 2010
  • Phenotypic analysis of LAT1 knockout mice, Ryuichi Ohgaki,Yuewei Li,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 147P-147P, 2010
  • Elucidation of urate transport mechanism by analysis of renal urate transporters transgenic mice, Toru Kimura,Ai Tsukada,Sirirat Amonpatumrat,Toshiyuki Fukutomi,Promsuk Jutabha,Kimiyoshi Ichida,Katsumasa Kawahara,Yoshikatsu Kanai,Naohiko Anzai,Hiroyuki Sakurai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 112, p. 66P-66P, 2010
  • 尿酸トランスポーターURAT1セミノックインマウスの生化学的解析, Vol. 135, No. 1, p. 13P-13P, 2010/01
  • ヒト有機アニオントランスポーター3(hOAT3)発現細胞及びラットを用いた、セレコキシブとメトトレキサート(MTX)との相互作用の検討, 前田 章光,鶴岡 秀一,牛島 健太郎,長谷川 豪紀,金井 好克,遠藤 仁,藤村 昭夫, 臨床薬理, (一社)日本臨床薬理学会, Vol. 40, No. Suppl., p. S231-S231, 2009/11
  • 調節蛋白の異常による腎疾患 上皮体制と病態, Vol. 32, No. 2, p. 139-146, 2009/10
  • 尿酸トランスポーターURAT1セミノックインマウスの解析, Vol. 82回, p. 3P-185, 2009/09
  • 栄養による個体機能制御と疾患 アミノ酸トランスポーターと癌, Vol. 28, No. 8, p. 789-793, 2009/07
  • Enhancement of cisplatin effect by the inhibitor of system L amino acid transporter 1, Kohichi Yamauchi,Hiroyuki Sakurai,Toru Kimura,Pattama Wiriyasermkul,Shushi Nagamori,Yasunao Kogashiwa,Yoshikatsu Kanai,Naoyuki Kohno, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 69, 2009/05
  • RACK1による抗癌剤排出輸送体BCRP/ABCG2の発現制御, 池淵 祐樹,伊藤 晃成,高田 龍平,安西 尚彦,金井 好克,鈴木 洋史, 薬剤学: 生命とくすり, (公社)日本薬剤学会, Vol. 69, No. Suppl., p. 114-114, 2009/04
  • 【小児の症候群】代謝 Fanconi-Bickel症候群, Vol. 72, No. 増刊, p. 348-348, 2009/04
  • 【尿酸排泄異常の成因】尿酸トランスポーター, Vol. 17, No. 1, p. 21-27, 2009/03
  • 調節蛋白の異常による腎疾患 輸送蛋白の細胞膜局在を制御する因子, Vol. 31, No. 3, p. 234-240, 2009/03
  • トランスポートソームの概念 トランスポートソーム その概念と生体膜輸送における重要性, No. 12, p. 68-75, 2009/02
  • DYNAMIC ROLES OF PROTEINS IN SYNAPTIC ADHERENS JUNCTION, Hidekazu Tanaka,Kazuaki Takafuji,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 137-137, 2009
  • THE PATHOPHYSIOLOGIC MECHANISM OF BAT1 P482L MUTATION, SPECIFIC IN JAPANESE CYSTINURIA CASES, Kenichiro Iio,Shushi Nagamori,Kazuaki Takafuji,Toru Kimura,Yoshikatsu Kanai, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 493-493, 2009
  • GLUCOSE TRANSPORTER 9 (GLUT9) AS A SERUM URATE REGULATOR AND CAUSATIVE GENE FOR RENAL HYPOURICEMIA, Shin Tadokoro,Hirotaka Matsuo,Toshinori Chiba,Shushi Nagamori,Akiyoshi Nakayama,Yousuke Kitamura,Hideharu Domoto,Kanokporn Phetdee,Pattama Wiriyasermkul,Junichiro Nishiyama,Yuji Morimoto,Yoshikatsu Kanai,Nariyoshi Shinomiya, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 495-495, 2009
  • COMPREHENSIVE ANALYSIS OF LEUCINE-STIMULATION DEPENDENT PHOSPHORYLATED PROTEINS, Kazuaki Takafuji,Pattama Wiriyasermkul,Kanyarat Promchan,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 213-213, 2009
  • CHARACTERIZATION OF SUBSTRATE RECOGNITION SITE IN L-TYPE AMINO ACID TRANSPORTER 1 (LAT1), Pattama Wiriyasermkul,Shushi Nagamori,Toru Kimura,Yoshikatsu Kanai, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 493-493, 2009
  • Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12) by yeast two-hybrid assay, Sunena Srivastava,Naohiko Anzai,Seiji Miyauchi,Daisaku Miura,Toshiyuki Fukutomi,Yoshikatsu Kanai,Vadivel Ganapathy,Hiroyuki Sakurai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 109, p. 68P-68P, 2009
  • CHARACTERIZATION OF AN ORPHAN TRANSPORTER IN SLC 7 FAMILY, Shushi Nagamori,Ryo Hatano,Hidekazu Tanaka,Yoshikatsu Kanai, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 493-493, 2009
  • Approaches to in vivo functions of transporters: Metabolomics and PET imaging, Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 109, p. 34P-34P, 2009
  • ANNEXIN A2-P11 COMPLEX INTERACTS WITH CD98HC, Kanyarat Promchan,Kazuaki Takafuji,Toru Kimura,Shushi Nagamori,Yoshikatsu Kanai, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 494-494, 2009
  • IDENTIFICATION OF USP14 AS A REGULATORY FACTOR OF BILE SALT EXPORT PUMP, Kousei Ito,Hiroko Yamaji,Tappei Takada,Naohiko Anzai,Yoshikatsu Kanai,Hiroshi Suzuki, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 347-347, 2009
  • STIMULATION OF AMINO ACIDS TO GROWTH SIGNAL IN HEK293T, Ryuichi Ohgaki,Narakorn Khunweeraphong,Yoshikatsu Kanai,Shushi Nagamori,Taku Hirata, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 213-213, 2009
  • A PROTEIN-PROTEIN INTERACTION IN C. ELEGANS; AMINO ACID TRANSPORTER-6 REQUIRES THE INTERACTION WITH GLYCOPROTEIN FOR FUNCTIONAL EXPRESSION, Kanokporn Phetdee,Shushi Nagamori,Taku Hirata,Kohei Hagiwara,Kazuya Nomura,Shohei Milani,Yoshikatsu Kanai, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 493-493, 2009
  • アミノ酸トランスポーターCAT5の機能解析, 木村 徹,Li Yuewei,金井 正美,安西 尚彦,川上 速人,櫻井 裕之,金井 好克, 日本薬理学雑誌, (公社)日本薬理学会, Vol. 133, No. 1, p. 17P-17P, 2009/01
  • 調節蛋白の異常による腎疾患 細胞膜輸送を調節する細胞内シグナル機構とその異常による疾患, Vol. 31, No. 2, p. 175-180, 2009/01
  • 薬効標的のトランスポーター, No. 12, p. 29-34, 2009/01
  • 薬効標的としてのトランスポーター アミノ酸トランスポーター 悪性腫瘍の診断と治療の分子標的としての可能性, No. 12, p. 218-224, 2009/01
  • 腎尿細管におけるMg2+輸送, Vol. 2009, p. 35-42, 2009/01
  • アミノ酸 その多様性とタンパク質創成技術 アミノ酸輸送と細胞機能, Vol. 2, No. 2, p. 109-120, 2009/01
  • Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia (vol 83, pg 744, 2008), Hirotaka Matsuo,Toshinori Chiba,Shushi Nagamori,Akiyoshi Nakayama,Hideharu Domoto,Kanokporn Phetdee,Pattama Wiriyasermkul,Yuichi Kikuchi,Takashi Oda,Junichiro Nishiyama,Takahiro Nakamura,Yuji Morimoto,Keiko Kamakura,Yutaka Sakurai,Shigeaki Nonoyama,Yoshikatsu Kanai,Nariyoshi Shinomiya, AMERICAN JOURNAL OF HUMAN GENETICS, CELL PRESS, Vol. 83, No. 6, p. 795-795, 2008/12
  • わが国の小児科医・研究者によって新たに提唱・発見された疾患、疾患概念、原因の究明された疾患 Hartnup病, Vol. 40, No. 12, p. 1979-1984, 2008/12
  • メトトレキサート(MTX)と相互作用が少ないNSAIDの探索 ヒトOAT3発現細胞を用いた検討, 前田 章光,鶴岡 秀一,牛島 健太郎,長谷川 豪紀,金井 好克,遠藤 仁,斉藤 和幸,藤村 昭夫, 臨床薬理, (一社)日本臨床薬理学会, Vol. 39, No. Suppl., p. S182-S182, 2008/11
  • 近位尿細管におけるアミノ酸輸送と代謝, Vol. 65, No. 5, p. 681-685, 2008/11
  • トランスポーター異常症と尿路結石, Vol. 31, No. 1, p. 13-19, 2008/06
  • 調節蛋白の異常による腎疾患 腎性低尿酸血症の遺伝子解析から明らかになった足場蛋白の重要性, Vol. 31, No. 1, p. 67-74, 2008/06
  • 腫瘍細胞のアミノ酸トランスポーターの発現とそれを標的とした診断と治療への応用の可能性, Vol. 33, No. 3, p. 108-117, 2008/05
  • L-type amino acid transporter 1 expression in prostate cancer: Association with cancer progression and high-grade malignancy, Takefumi Satoh,Takeshi Sakata,Isao Okayasu,Golam Ferdous,Tomoko Tsuruta,Tomoko Muto,Akinori Ueno,Yoshikatsu Kanai,Hitoshi Endou,Shiro Baba, JOURNAL OF UROLOGY, ELSEVIER SCIENCE INC, Vol. 179, No. 4, p. 105-105, 2008/04
  • 脱ユビキチン化酵素USP14によるBSEPの翻訳後調節機構の解析, Vol. 68, No. Suppl., p. 183-183, 2008/04
  • MDR3/ABCB4の共役因子RACK1による発現制御, 池淵 祐樹,高田 龍平,伊藤 晃成,吉門 崇,安西 尚彦,金井 好克,鈴木 洋史, 薬剤学: 生命とくすり, (公社)日本薬剤学会, Vol. 68, No. Suppl., p. 181-181, 2008/04
  • メトトレキサート(MTX)と相互作用が少ないNSAIDの探索 ヒトOAT3発現細胞を用いた検討, 前田 章光,鶴岡 秀一,金井 好克,遠藤 仁,斉藤 和幸,藤村 昭夫, 日本腎臓学会誌, (一社)日本腎臓学会, Vol. 50, No. 3, p. 291-291, 2008/04
  • 【高尿酸血症・痛風Update】基礎研究の進歩 腎尿細管における尿酸輸送の分子メカニズム 尿酸トランスポーターの局在と機能, Vol. 66, No. 4, p. 659-666, 2008/04
  • Characterization of short chain fatty acid butyrate transport by novel liver-specific organic anion transporter OAT7, Naohiko Anzai,Xin He,Takeshi Ueno,Ho Jung Shin,Kazuhiro Miyao,Ai Yamanishi,Hitoshi Endou,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 106, p. 257P-257P, 2008
  • Search for the novel transporters involved in energy metabolism using DNA microarray, Taku Hirata,Tomoko Muto,Babu Ellappan,Chunji Jing,Naohiko Anzai,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 106, p. 109P-109P, 2008
  • Human organic cation transporter OCT3 (SLC22A3) SNPs and their transport activities of histamine, Naohiko Anzai,Takeshi Sakata,Shinichi Narikawa,Michio Takeda,Daisaku Miura,Toru Kimura,Toshiyuki Fukutomi,Yoshikatsu Kanai,Hitoshi Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 106, p. 152P-152P, 2008
  • メタボロミクスによるトランスポーター研究の新展開, Vol. 26, No. 1, p. 18-23, 2008/01
  • 【腎臓学 この一年の進歩】腎生理のトピックス 特に遺伝子改変動物とシグナル系に関して, Vol. 50, No. 1, p. 1-4, 2008/01
  • Testicular toxicology of pubescent and adult rats prenatally exposure to 3,3′,4,4′,5-pentachlorobiphenyl, Shin Wakui,Yousuke Akagi,Tomoko Muto,Kiyofumi Yokoo,Shyou Hirono,Yasuko Kobayashi,Yousuke Kamei,Kinji Shirota,Fumiaki Akahori,Yoshihiko Suzuki,Hiroshi Hano,Hitoshi Endou,Yoshikatsu Kanai, Journal of Toxicologic Pathology, Vol. 20, No. 3, p. 133-140, 2007/10/09
  • 【これだけは知っておきたい分子腎臓学2007】Organic anion transporters, Vol. 63, No. 4, p. 470-473, 2007/10
  • 【利尿薬の最新知識と使い方】利尿作用の分子機序, Vol. 37, No. 8, p. 883-888, 2007/08
  • Tissue distribution and intrarenal localization of IKEPP/NHERF4 of a member of the NHERF family, Xin He,Naohiko Anzai,Taku Hirata,Yoshikatsu Kanai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 21, No. 5, p. A544-A544, 2007/04
  • Human urate transporter URAT1 mediates the transport of salicylate., Naohiko Arizai,Sirinun Nilwarangkoon,Daisaku Miura,Rie Kofuji,Yoshikatsu Kanai,Hiroshi Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, p. 148P-148P, 2007
  • Renal urate transportsome: Toward the understanding of pathogenetic role of renal urate handling for serum urate disorders, Naohiko Anzai,Yoshikatsu Kanai,Hitoshi Endou, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, PHARMACEUTICAL SOC JAPAN, Vol. 127, p. 21-22, 2007
  • Identification of the binding protein for a neutral amino acid transporter B(0)AT1 related to Hartnup disorder that controls its apical sorting., Naohiko Anzai,Taku Hirata,Akio Koizumi,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, p. 90P-90P, 2007
  • Functional characterization of a novel prostaglandin-specific organic anion transporter (OAT-PG), Taku Hirata,Katsuko Shiraya,Naohiko Anzai,Ryo Hatano,Satoshi Sanada,Mitsunobu Matsubara,Shigeaki Muto,Hitoshi Endou,Yoshikatsu Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 103, p. 218P-218P, 2007
  • 腎におけるプロスタグランジンシグナリングの新展開, Vol. 2007, p. 42-49, 2007/01
  • 遺伝性低リン血症性くる病原因遺伝子type IIc Na/PiのPTHによる調節機構, 瀬川博子,伊藤美紀子,安西尚彦,金井好克,宮本賢一, 日本腎臓学会誌, (一社)日本腎臓学会, Vol. 48, No. 3, p. 261-261, 2006/04/25
  • Identification and functional characterization of a novel cationic amino acid transporter CAT5 specifically expressed in placenta, YW Li,M Kanai-Azuma,T Hirata,N Anzai,H Kawakami,H Endou,Y Kanai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 20, No. 5, p. A840-A841, 2006/03
  • Role of intracellular C-terminal domain of the catalytic subunit of system b(0,+) for its trafficking and the RACK1 binding., N Anzai,S Sakamoto,A Crairoungdua,T Ichikawa,H Endou,Y Kanai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 20, No. 5, p. A1236-A1236, 2006/03
  • The voltage-driven organic anion transport of type I sodium-phosphate cotransporter and OATv1, P Jutabha,A Chairoungdua,N Anzai,Y Kanai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 20, No. 5, p. A1235-A1235, 2006/03
  • Transport of nicotinate by human organic anion transporters of SLC22 family, He, X,N Anzai,M Ljubojevic,T Ueno,T Fukutomi,T Sakata,Sabolic, I,T Hirata,H Endou,Y Kanai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 20, No. 5, p. A1143-A1144, 2006/03
  • Functional characterization and tissue localization of a novel liver-specific organic anion transporter OAT7, HJ Shin,N Anzai,He, X,Y Kanai,H Endou, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 20, No. 5, p. A840-A840, 2006/03
  • Molecular identification of a novel prostaglandin-specific organic anion transporter (OAT-PG) that is colocalized with prostaglandin producing enzyme Cox-2 in the distal tubular cells., T Hirata,K Shiraya,P Jutabha,T Muto,N Anzai,R Hatano,S Sanada,M Matsubara,S Muto,H Endou,Y Kanai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 20, No. 5, p. A1226-A1226, 2006/03
  • Expression of LAT1 predicts progression of transitional cell carcinoma of the upper urinary tract, K Nakanishi,H Matsuo,Y Kanai,H Endou,S Hiroi,S Tominaga,S Aida,H Kasamatsu,S Matsuyama,T Kawai, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 20, No. 4, p. A223-A223, 2006/03
  • 【水・電解質異常の新展開】アミノ酸輸送体と疾患, Vol. 216, No. 9, p. 692-698, 2006/03
  • アミノ酸トランスポーター, Vol. 25, No. 3, p. 280-286, 2006/02
  • 【分子腎臓病学 分子生物学的アプローチと分子病態生理学】基礎編 腎臓の構造と機能 腎臓における物質輸送の分子機構 有機カチオン/アニオントランスポーター, Vol. 64, No. 増刊2 分子腎臓病学, p. 169-175, 2006/02
  • Identification and characterization of a novel renal prostaglandin-specific organic anion transporter (OAT-PG) structurally distinct from PGT, N Anzai,K Shiraya,T Hirata,P Jutabha,R Hatano,S Sanada,M Matsubara,S Muto,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 111P-111P, 2006
  • Recent advances in SLC22 organic anion transporters, Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 22P-22P, 2006
  • Substrate recognition mechanisms of a novel cationic amino acid transporter CAT5, YW Li,M Kanai,T Hirata,N Anzai,H Kawakami,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 218P-218P, 2006
  • The suppression of mTOR signaling pathway underlies the anti-tumor effects of LAT1 inhibitors, A Chairoungdua,P Kongsuphol,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 183P-183P, 2006
  • Structural determinants in the heavy chain subunits of heterodimeric amino acid transporters for recognition of light chains, A Nesar,P Sangwoung,A Chairoungdua,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 187P-187P, 2006
  • Transport of methylmercury through the epithelial type amino acid transport system B-0, Rafiqul, I,P Jutabha,T Hirata,N Anzai,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 187P-187P, 2006
  • Role of intracellular C-terminal domain of the catalytic subunit of system B-0,B-+ for its trafficking and the protein-protein interaction, N Anzai,S Sakamoto,A Chairoungdua,T Ichikawa,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 126P-126P, 2006
  • Molecular identification and functional characterization of a novel Organic Anion Transporter OAT9 that is expressed in brain and kidney, T Hirata,B Ellappan,N Anzai,H Xin,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 98P-98P, 2006
  • Transport of nicotinate by human organic anion transporter hOAT2 and its possible interaction with transport of salicylate, He, X,N Anzai,T Ueo,T Fukutomi,T Sakata,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 126P-126P, 2006
  • Localization of serine transporters Asc-1 and SNAT2 in the rat brain, Motohide Tokunaga,H. Matsuo,H. Ishimine,S. Tsukada,T. Kazama,Y. Kanai,Y. Kobayashi,J. Fukuda, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 55, p. S83-S83, 2006
  • Transporter-mediated toxicity of cephaloridine and ochratoxin A assessed by DNA microarray analysis, P Jutabha,T Muto,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 100, p. 215P-215P, 2006
  • 腎尿酸輸送機構 最近の話題, Vol. 2008, p. 91-99, 2006/01
  • 腎尿細管のトランスポーター 疾患から機能へのアプローチ, Vol. 4, No. 2, p. 1-17, 2005/11
  • 注目される腎関連蛋白 Glucose transporter 2(GLUT2), Vol. 59, No. 4, p. 582-584, 2005/10
  • 注目される腎関連蛋白 Urate transporter 1(URAT1), Vol. 59, No. 4, p. 586-588, 2005/10
  • シスチン尿症の遺伝子診断およびその臨床応用, Vol. 18, No. 7, p. 810-816, 2005/07
  • グリア細胞のシスチン-グルタミン酸交換輸送機構と酸化ストレス, Vol. 23, No. 2, p. 219-222, 2005/02
  • 尿細管異常症 近位尿細管輸送機能異常 基礎医学的観点から, Vol. 58, No. 2, p. 185-189, 2005/02
  • Cross-linking CD98-mediates integrin signaling and tumorigenesis, A Chairoungdua,G Ferdous,M Takahashi,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 140P-140P, 2005
  • Reconstitution into liposome of organic anion transporters, P Jutabha,N Anzai,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 280P-280P, 2005
  • Amino acid transporter inhibitors: Their therapeutic potential, Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 24P-24P, 2005
  • Identification and functional characterization of a novel organic anion transporter OAT9, H Hasannejad,T Hirata,E Babu,H Yokoyama,N Anzai,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 256P-256P, 2005
  • Functional characterization and tissue localization of SLC22 organic anion transporter OAT7, HJ Shin,N Anzai,A Enomoto,DK Kim,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 201P-201P, 2005
  • Overexpression of LAT1 and 4F2hc in clear cell RCCs and clinicopathological relevance LAT1, A Nesar,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 258P-258P, 2005
  • Cadherin expression in human liver cell line with 3D radial-flow culture system, Y Iribe,S Aoshima,K Miki,S Nagamori,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 141P-141P, 2005
  • Regulation of renal urate transporter URAT1 transport function by PDZ domain protein PDZK1, N Anzai,H Miyazaki,T Hirata,He, X,A Toki,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 120P-120P, 2005
  • Identification of a novel organic anion transporter OAT6 mediating carnitine transport in mouse liver and kidney, N Anzai,H Tsuchida,HJ Shin,E Babu,P Jutabha,K Sakama,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 281P-281P, 2005
  • Identification and characterization of a novel mouse organic anion transporter (OAT10), K Shiraya,T Hirata,N Anzai,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 120P-120P, 2005
  • Functional characterization of a novel cationic amino acid transporter (CAT5), YW Li,T Hirata,N Anzai,Y Iribe,M Hosoyamada,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 280P-280P, 2005
  • Identification of CD98 binding proteins and elucidate its physiological role in vivo, G Ferdous,A Chairoungdua,M Takahashi,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 140P-140P, 2005
  • Mechanism of substrate selectivity of human organic anion transporter 1, S Nimitvilai,P Jutabha,S Sophasan,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 282P-282P, 2005
  • Identification of a novel SLC7 family member Asc-2-like transporter in kidney, S Nilwarangkoon,T Hirata,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 281P-281P, 2005
  • Real-time dual-color imaging of trafficking, cellular dynamics, and viability of breast cancer cells in the portal vein., K Tsuji,K Yamauchi,M Yang,P Jiang,M Bouvet,M Al-Zaid,H Endo,Y Kanai,K Yamashita,AR Moossa,RM Hoffman, BREAST CANCER RESEARCH AND TREATMENT, SPRINGER, Vol. 94, p. S28-S28, 2005
  • Identification of a novel brain-type organic anion transporter 1 (BOAT1), T Hirata,E Babu,K Shiraya,N Anzai,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 283P-283P, 2005
  • Reduction of mTOR activity by inhibited LAT1, the neutral amino acid transporter, P Kongsuphol,A Chairoungdua,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 141P-141P, 2005
  • Identification of the intracellular binding protein with proton-coupled oligopeptide transporter PEPT2 using yeast two-hybrid assay, T Sakata,N Anzai,R Noshiro,H Miyazaki,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 257P-257P, 2005
  • Identification of a testis-type organic anion transporter 1 (TOAT1), E Babu,T Hirata,N Anzai,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 281P-281P, 2005
  • Role of C-terminus of the heterodimeric amino acid transporter family (SLC7) in membrane targeting, P Sangwoung,A Chairoungdua,P Jutabha,M Fujimura,H Endou,Y Kanai, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 97, p. 141P-141P, 2005
  • Functional Characterization and Immunohistochemical Localization of Organic Anion Transporter 1 (S1c22a6) from Mouse Kidney, KOJIMA Shiho,ENOMOT0 Atsushi,TSUCHIDA Hiroki,HOSOYAMADA Makoto,KANAI Yoshikatsu,HASEGAWA Makoto,ENDOU Hitoshi, Journal of the Kyorin Medical Society, The Kyorin Medical Society, Vol. 35, No. 4, p. 400-406, 2004/12/30
  • 尿酸トランスポーターの機能制御と疾患 (第26回 生体膜と薬物の相互作用シンポジウム 講演要旨集) -- (特別企画2:トランスポーターの機能制御;疾患との関連を中心に), Vol. 124, No. 0, p. 25-28, 2004/11/25
  • 尿酸トランスポーターの機能制御と疾患, 金井好克,安西尚彦,細山田真,遠藤仁, 生体膜と薬物の相互作用シンポジウム講演要旨集, Vol. 26th, p. 25-28, 2004/11/01
  • 尿素トランスポーターの分子実体と尿濃縮における役割, Vol. 57, No. 4, p. 478-482, 2004/10
  • 尿酸トランスポーターの分子実体, Vol. 28, No. 1, p. 1-5, 2004/07
  • Molecular identification of a novel renal apical organic anion transporter OAT5 that transports the mycotoxin ochratoxin A, T Sakata,N Anzai,P Jutabha,A Enomoto,T Hirata,H Yokoyama,SH Cha,H Miyazaki,Y Kanai,H Endou, TOXICOLOGY AND APPLIED PHARMACOLOGY, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 197, No. 3, p. 297-298, 2004/06
  • Variation of gene expression profile by the inhibition of single molecular target LAT1, system L amino acid transporter in laryngeal squamous-cell-carcinoma cells, T Hirata,Y Kanai,A Matsuda,Y Iribe,DK Kim,R Islam,T Muto,A Chairoungdua,N Kohno,M Hasegawa,H Endou, TOXICOLOGY AND APPLIED PHARMACOLOGY, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 197, No. 3, p. 218-218, 2004/06
  • Establishment of the N-ethylmaleimide sensitive system L2 amino acid transporters family, SLC43, A Chairoungdua,Y Kanai,E Babu,H Endou, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 18, No. 8, p. C280-C280, 2004/05
  • A new classification of phenotype-genotype of cystinuria patients in Japan, T Ueda,Y Shigeta,S Sakamoto,M Fujimura,Y Awa,Y Naya,K Akakura,T Ichikawa,T Igarashi,Y Kanai,H Endou,H Ito, JOURNAL OF UROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 171, No. 4, p. 297-297, 2004/04
  • Identification of a novel missense mutation of SLC7A9 frequent in Japanese cystinuria population that cause membrane targeting defect of the transporter protein by introducing a bulky side chain on its C-terminus, S Sakamoto,Y Shigeta,T Ueda,A Chairoungdua,M Fujimura,Y Awa,Y Naya,K Akakura,T Ichikawa,T Igarashi,Y Kanai,H Endou,H Ito, JOURNAL OF UROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 171, No. 4, p. 296-297, 2004/04
  • Characterization of a novel rat organic anion transporter OAT5 as an organic anion/dicarboxylate exchanger at the apical membrane of renal proximal tubules, T Hirata,P Jutabha,N Anzai,Y Kanai,H Endou, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 18, No. 5, p. A1250-A1250, 2004/03
  • Identification of the intracellular binding protein with proton-coupled oligopeptide transporter PEPT2 using yeast two-hybrid assay, N Anzai,R Noshiro,H Miyazaki,P Jutabha,Y Kanai,H Endou, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 18, No. 4, p. A695-A695, 2004/03
  • The multivalent PDZ domain protein PDZK1 upregulates the transport activity of renal urate-anion exchanger URAT1 via its C-terminal, N Anzai,H Miyazaki,T Hirata,P Jutabha,Y Kanai,H Endou, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 18, No. 4, p. A320-A321, 2004/03
  • Functional characterization of a voltage-driven organic anion transporter OAT(V)1: the exit path of organic anion at the apical membrane of renal proximal tubule, P Jutabha,Y Kanai,M Hosoyamada,A Chairoundua,Y Iribe,H Endou, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 18, No. 4, p. A707-A707, 2004/03
  • Study of protein-protein interactions of LAT1 in cell membrane of cancer cell lines, M Javan,Y Kanai,A Chairoungdua,S Sakamoto,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 138P-138P, 2004
  • Characterization of a voltage-driven organic anion transporter OAT(V)1: the exit path of organic anion at the apical membrane of renal proximal tubule, P Jutabha,Y Kanai,M Hosoyamada,Y Iribe,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 262P-262P, 2004
  • Cloning and characterization of a novel rat organic anion transporter (OAT5) at the apical side of renal proximal tubules, T Hirata,N Anzai,P Jutabha,H Yokoyama,T Sakata,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 262P-262P, 2004
  • Characterization of FLC4 human hepatocarcinoma cells as a model cell line for system L amino acid transporter LAT3, E Babu,A Chairoungdua,R Islam,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 127P-127P, 2004
  • The role of CD98 in cell adhesion and cancer, Y Iribe,A Chairoungdua,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 127P-127P, 2004
  • Neutral amino acid transporter LATs as targets for anti-cancer therapy, Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 40P-40P, 2004
  • Identification of a novel system y(+) cationic amino acid transporter expressed in placenta, YW Li,Y Kanai,Y Iribe,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 242P-242P, 2004
  • Transport mechanisms of a renal apical drug transporter, organic anion transporter 4, H Miyazaki,N Anzai,P Jutabha,S Ekaratanawong,R Noshiro,HJ Shin,T Sakata,T Hirata,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 112P-112P, 2004
  • Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions, T Sakata,N Anzai,HJ Shin,R Noshiro,T Hirata,H Yokoyama,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 244P-244P, 2004
  • Identification of a neutral amino acid transporter corresponding to system L2, A Chairoungdua,Y Kanai,B Ellappan,Y Iribe,M Takahashi,K Sakama,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 94, p. 242P-242P, 2004
  • The molecular mechanisms of absorption, permeation of blood-tissue barriers and cytotoxicity of methylmercury mediated by amino acid transporters., KANAI YOSHIKATSU,ENDO HITOSHI,HOSOYAMADA MAKOTO,KIM DO KYUNG,ANZAI NAOHIKO,IRIBE YUJI,TERADO YUICHI, 水俣病に関する総合的研究 平成15年度, p. 117-129, 2004
  • Interaction of the PDZ domain protein PDZK1 with urate/anion exchanger URAT1, H Miyazaki,N Anzai,T Hirata,Y Iribe,H Nonoguchi,Y Kanai,K Tomita,H Endou, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 14, p. 307A-307A, 2003/11
  • Cloning and characterization of a novel organic anion transporter (OAT5): Apical isoform of the proximal tubules in rat kidney., T Hirata,N Anzai,P Jutabha,A Enomoto,H Miyazaki,T Sakata,H Nonoguchi,Y Kanai,K Tomita,H Endou, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 14, p. 57A-57A, 2003/11
  • Interaction of the PDZ domain proteins with organic anion transporter 4 (OAT4), H Miyazaki,N Anzai,T Hirata,Y Iribe,H Nonoguchi,Y Kanai,K Tomita,H Endou, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 14, p. 307A-307A, 2003/11
  • A novel voltage-driven organic anion transporter at apical membrane of renal proximal tubule: The exit path of organic anions in kidney, P Jutabha,Y Kanai,M Hosoyamada,A Chairoungdua,Y Iribe,H Miyazaki,T Hirata,K Tomita,H Endou, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 14, p. 305A-306A, 2003/11
  • 【浸潤性膵管癌の診療をどうするか】膵癌に対する遺伝子治療の現況, Vol. 58, No. 12, p. 1509-1513, 2003/11
  • 臨床検査医学の進歩 尿酸トランスポーターと腎性低尿酸血症, Vol. 51, No. 9, p. 892-897, 2003/09
  • 【チャネル・トランスポーターの分子医学2003】アミノ酸輸送体の多様性 アミノ酸代謝異常症の分子基盤, Vol. 40, No. 7, p. 782-790, 2003/06
  • シスチン尿症の病態解析, Vol. 94, No. 2, 2003/02/15
  • Expression cloning of a novel branched-chain amino acid transporter., E Babu,A Chairoungdua,N Ahmed,N Matsumoto,T Kuroda,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 225P-225P, 2003
  • Molecular cloning and characterization of a novel apical organic anion transporter in pig kidney., P Jutabha,Y Kanai,M Hosoyamada,A Chairoungdua,Y Iribe,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 226P-226P, 2003
  • The involvement of mTOR signaling pathway in CD98-mediated cellular responses., A Chairoungdua,Y Kanai,S Sakamoto,S Tangtrongsup,M Takahashi,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 125P-125P, 2003
  • Investigation of effect of LAT1 inhibitors on gene expression profile in T24 cell., S Baniasadi,Y Iribe,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 228P-228P, 2003
  • Characterization of newly identified system L-like amino acid transporter., Y Iribe,S Baniasadi,YW Li,Y Kanai,H Endou, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 91, p. 226P-226P, 2003
  • メチル水銀の吸収,変換,生体内動態,排せつの分子機構等に関する研究―アミノ酸輸送体を介するメチル水銀の吸収及び血液・組織関門透過と細胞毒性発現の分子機構―, 金井好克,遠藤仁,細山田真,安西尚彦,入部雄司,寺戸雄一, 水俣病に関する総合的研究 平成14年度, p. 47-53, 2003
  • 【ヒト培養肝細胞の機能 その各種機能発現】ヒト培養細胞の肝機能発現とその利用法 バイオ人工肝の多角的な応用をめざして, Vol. 34, No. 13, p. 516-523, 2002/11
  • 【ヒト培養肝細胞の機能 その各種機能発現】肝細胞のトランスポーター, Vol. 34, No. 13, p. 541-544, 2002/11
  • アミノ酸トランスポーターの構造機能と栄養学的重要性, No. 165, p. 13-19, 2002/11
  • Identification of a human epithelial aromatic amino acid transporter (TAT1) and its localization in the basolateral membrane of proximal tubules., H Miyazaki,DK Kim,A Chairoungdua,N Anzai,Y Iribe,Y Kanai,K Tomita,H Endou, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 13, p. 64A-65A, 2002/09
  • 細胞医学への回帰 蛋白質の動的表現 アミノ酸トランスポーターと細胞機能 タンパク質間相互作用を介した機能連関, Vol. 114, No. 1, p. 34-37, 2002/08
  • 【新時代の糖尿病学 病因・診断・治療研究の進歩】糖尿病基礎研究の進歩 糖代謝概論 腎尿細管における糖輸送の分子機構, Vol. 60, No. 増刊7 新時代の糖尿病学(1), p. 141-150, 2002/07
  • 【神経伝達物質のトランスポーター】多選択性中性アミノ酸トランスポーターLAT1の中枢神経における役割, Vol. 24, No. 4, p. 367-377, 2002/04
  • ヘテロ二量体型アミノ酸トランスポーターファミリーの基質認識の機序, No. 36, p. 9-18, 2002/02
  • Role of amino acid transporters in malignant tumors: the anti-tumor effect of amino acid transporter inhibition and its potentiality for clinical application, Y Kanai,H Endou, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 37P-37P, 2002
  • Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters LAT1 and LAT2, E Morimoto,M Takahashi,A Matsuda,E Babu,Y Kanai,H Endou, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 223P-223P, 2002
  • CDNA cloning of a human cystine/glutamate transporter and the examination of its regulation by oxidative stress in glioma cells, JY Kim,Y Shigeta,HW Choi,H Teraoka,Y Kanai,H Endou, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 223P-223P, 2002
  • Identification and characterization of multispecific organic anion transporter 7 expressed in human liver, HJ Shin,A Enomoto,HW Choi,DK Kim,A Toki,Y Kanai,H Endou, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 222P-222P, 2002
  • Identification and characterization of a novel epithelial aromatic amino acid transporter TAT1, DK Kim,Y Kanai,A Chairoungdua,A Enomoto,J Inatomi,N Anzai,M Alebouyeh,H Endou, JAPANESE JOURNAL OF PHARMACOLOGY, JAPANESE PHARMACOLOGICAL SOC, Vol. 88, p. 223P-223P, 2002
  • Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells, Vol. 1565, No. 1, p. 112-122, 2002
  • 【トランスポーターと機能】小腸及び腎におけるアミノ酸吸収を担うトランスポーター, Vol. 199, No. 3, p. 207-211, 2001/10
  • CD98を介するアミノ酸輸送と感受システムの誘導機序, 新居智子,瀬川博子,伊藤美紀子,竹谷豊,武田英二,金井好克,遠藤仁,宮本賢一, 日本栄養・食糧学会総会講演要旨集, (公社)日本栄養・食糧学会, Vol. 55th, p. 206-206, 2001/04/01
  • 【薬物トランスポーター 多選択的基質認識の分子基盤】多選択性アミノ酸トランスポーターファミリー LATファミリー, Vol. 46, No. 5, p. 629-637, 2001/04
  • II型膜糖蛋白を必要とするアミノ酸輸送担体ファミリーの同定とその遺伝子異常症の解析, 瀬川博子,新居智子,武田英二,金井好克,遠藤仁,宮本賢一, 生化学, (公社)日本生化学会, Vol. 73, No. 2, p. 141-141, 2001/02/25
  • アミノ酸トランスポーターの構造機能と栄養学的重要性, Vol. 2001, p. 13-20, 2001/02
  • Individual difference and gene polymorphism of drug excretion activity liver and remnal in Japanese( human science promotion foundation S )., ENDO HITOSHI,KANAI YOSHIKATSU,TAKEDA MASAO,HOSOYAMADA MAKOTO,SHA SEKIKO,INATOMI JUN,KIN TOKEI,MIYANOSHITA AKIHIKO, 創薬等ヒューマンサイエンス研究重点研究報告書 平成12年度 第7分野 ヒト組織を用いた薬物の有効性、安全性に関する研究, p. 14-20, 2001
  • 日本人の肝及び腎の薬物排せつ能の個人差と遺伝子多型 (ヒューマンサイエンス振興財団S), 遠藤仁,金井好克,武田理夫,細山田真,車碩こう,稲富淳,金徒慶,宮ノ下昭彦, 創薬等ヒューマンサイエンス研究総合研究報告書 平成11‐12年度 第7分野 ヒト組織を用いた薬物の有効性、安全性に関する研究, p. 11-16, 2001
  • Comparison of Japanese Europe person of the drug transporter gene ( human science promotion foundation S )., ENDO HITOSHI,KANAI YOSHIKATSU,TAKEDA MASAO,HOSOYAMADA MAKOTO,KURUMA SEKIKO,INATOMI ATSUSHI,KIN TOKEI,KEPPLER D,KOENIG J, 創薬等ヒューマンサイエンス研究 平成12年度 国際共同研究事業研究報告書, p. 123-129, 2001
  • 脳の機能とアミノ酸栄養 アミノ酸の細胞膜輸送機序(, No. 159, p. 11-16, 2000/12
  • シスチン尿症の原因遺伝子の同定と機能解析, 瀬川博子,宮本賢一,金井好克,遠藤仁,武田英二, 四国医学雑誌, 徳島医学会, Vol. 56, No. 5, p. 196-196, 2000/10/25
  • II型膜糖蛋白質rBATにより活性化されるトランスポーター(BAT1)のcDNAクローニング, 瀬川博子,ARCHIT C,武田英二,遠藤仁,宮本賢一,金井好克, 生化学, (公社)日本生化学会, Vol. 72, No. 8, p. 992-992, 2000/08/25
  • 【グルタミン酸 毒性からトランスポーターまで】グルタミン酸トランスポーター分子の機能特性, Vol. 12, No. 2, p. 161-168, 2000/06
  • II型膜糖蛋白質rBATにより活性化されるアミノ酸トランスポーターのクローニング, 瀬川博子,CHAIROUNGDUA A,武田英二,遠藤仁,宮本賢一,金井好克, 日本栄養・食糧学会総会講演要旨集, (公社)日本栄養・食糧学会, Vol. 54th, p. 190-190, 2000/04/01
  • 甲状腺腫瘍におけるアミノ酸トランスポーターLAT1,LAT2の発現, 後藤 明輝,金井 好克,遠藤 仁,坂本 穆彦, 日本病理学会会誌, (一社)日本病理学会, Vol. 89, No. 1, p. 296-296, 2000/03
  • 日本人の肝及び腎の薬物排せつ能の個人差と遺伝子多型 (ヒューマンサイエンス振興財団S), 遠藤仁,金井好克,武田理夫,細山田真,車碩こう,稲富淳,金徒慶,宮ノ下昭彦, 創薬等ヒューマンサイエンス総合研究事業重点研究報告 平成11年度 第7分野 ヒト組織を用いた薬物の有効性、安全性に関する研究, p. 13-17, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(3)」血液・脳関門トランスポーター, Vol. 18, p. 368-369, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(2)」モノアミントランスポーター, Vol. 18, p. 246-247, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(1)」グルタミン酸トランスポーター, Vol. 18, p. 124-125, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(3)」血液・脳関門トランスポーター, Vol. 18, p. 368-369, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(2)」モノアミントランスポーター, Vol. 18, p. 246-247, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(1)」グルタミン酸トランスポーター, Vol. 18, p. 124-125, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(3)」血液・脳関門トランスポーター, Vol. 18, p. 368-369, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(2)」モノアミントランスポーター, Vol. 18, p. 246-247, 2000
  • 連載・臨床に必要な神経薬理「脳のトランスポーターと薬理(1)」グルタミン酸トランスポーター, Vol. 18, p. 124-125, 2000
  • Amino acid transporters: molecular structure and physiological roles, Y Kanai,H Segawa,A Chairoungdua,JY Kim,DK Kim,H Matsuo,SH Cha,H Endou, NEPHROLOGY DIALYSIS TRANSPLANTATION, OXFORD UNIV PRESS, Vol. 15, p. 9-10, 2000
  • Ishii,H, Sasaki,Y, Goshima,Y, Kanai,Y, Endou,H, Ayusawa,D, Ono,H, Miyamae,T, Misu,Y: Involvement of rBAT in Na+ -dependent and -independent transport of the neurotransmitter candidate L-DOPA in Xenopus laevis oocytes injected with rabbit small intestin・・・, Biochim. Biophys. Acta, Vol. 1466: 61-70, 2000
  • System Lアミノ酸トランスポーターの第二のアイソフォームのクローニングとその基質選択性及び機能特性の検討, 金 徒慶,瀬川 博子,深沢 芳樹,金 珠英,于 爾康,Chairoungdua Arthit,金井 好克,遠藤 仁, 日本薬理学雑誌, (公社)日本薬理学会, Vol. 114, No. 4, p. 54P-54P, 1999/10
  • リジン尿性蛋白不耐症原因遺伝子y+LAT1の機能解析, 新居 智子,瀬川 博子,金井 好克,遠藤 仁,岸田 祐枝,大城戸 真喜子,宮本 賢一,武田 英二,青木 美奈子,深尾 敏幸, 日本先天代謝異常学会雑誌, 日本先天代謝異常学会, Vol. 15, No. 2, p. 148-148, 1999/10
  • アミノ酸輸送系Lの第二のアイソフォームのcDNAクローニング, 瀬川 博子,深沢 芳樹,宮本 賢一,武田 英二,遠藤 仁,金井 好克, 生化学, (公社)日本生化学会, Vol. 71, No. 8, p. 933-933, 1999/08
  • Cloning and gene expression mechanism of neutral amino acid transport system L., 宮本賢一,金井好克,瀬川博子,新居智子,竹谷豊,谷佳子,大城戸真喜子,遠藤仁,武田英二, 日本栄養・食糧学会総会講演要旨集, (公社)日本栄養・食糧学会, Vol. 53rd, p. 219-219, 1999/04/20
  • C-19 ラットおよびヒト多選択性有機アニオントランスポーターによる抗腫瘍薬の基質認識(一般口演,第27回杏林医学会総会), Vol. 30, No. 1, 1999/03/31
  • System Lアミノ酸トランスポーターの基質選択性と輸送特性の検討, 深沢 芳樹,瀬川 博子,内野 裕史,金井 好克,遠藤 仁, 日本薬理学雑誌, (公社)日本薬理学会, Vol. 113, No. 2, p. 35P-35P, 1999/02
  • Na<sup>+</sup>依存性アミノ酸トランスポーター, Vol. 50, p. 291-297, 1999
  • アミノ酸輸送体:アミノ酸尿症, Vol. 14, p. 879-883, 1999
  • Na<sup>+</sup>依存性アミノ酸トランスポーター, Vol. 50, p. 291-297, 1999
  • アミノ酸輸送体:アミノ酸尿症, Vol. 14, p. 879-883, 1999
  • Na<sup>+</sup>依存性アミノ酸トランスポーター, 生体の科学, Vol. 50, p. 291-297, 1999
  • アミノ酸輸送体:アミノ酸尿症, Vol. 14, p. 879-883, 1999
  • 4F2抗原heavy chainにより活性化されるアミノ酸トランスポーターの同定, 瀬川博子,宮本賢一,武田英二,遠藤仁,金井好克, 日本分子生物学会年会プログラム・講演要旨集, Vol. 21st, 1998/11
  • II型膜糖タンパク質4F2hc(CD98)により活性化されるアミノ酸トランスポーターの発現クローニング, 瀬川 博子,宮本 賢一,武田 英二,遠藤 仁,金井 好克, 生化学, (公社)日本生化学会, Vol. 70, No. 8, p. 889-889, 1998/08
  • Improvement of hyperglycemia by a novel orally active inhibitor of Na-glucose cotransporter, A Oku,K Ueta,K Arakawa,M Matsumoto,A Saito,K Ikezawa,K Tsujihara,M Anai,T Asano,Y Kanai,H Endo, DIABETES, AMER DIABETES ASSOC, Vol. 47, p. A420-A420, 1998/05
  • C-23 マウス腎有機アニオントランスポーター(mOAT1)のクローニングとその解析(一般口演,第26回杏林医学会総会), Vol. 29, No. 1, 1998/03/31
  • C-25 有機アニオン輸送体(OAT1)安定発現マウス近位直尿細管終末部(S_3)由来細胞株を用いたセファロリジン(CER)腎障害発症機構の解明(一般口演,第26回杏林医学会総会), Vol. 29, No. 1, 1998/03/31
  • In vitro血液脳関門輸送実験系を用いたL-cystine輸送機構, Vol. 58, 1998/03/05
  • アミノ酸トランスポーターの構造・機能とその病態, Vol. 15: 105-112, 1998
  • Na<sup>+</sup>/グルコース共輸送体, No. 臨時増刊, p. 232-237, 1998
  • 機能を手がかりにしたクローニング, No. 臨時増刊, p. 66-70, 1998
  • トランスポーターの薬理, Vol. 42, p. 887-894, 1998
  • アミノ酸トランスポーターの構造・機能とその病態, Vol. 15, p. 105-112, 1998
  • アミノ酸交換輸送体, Vol. 44, p. 215-220, 1998
  • アミノ酸トランスポーターの構造・機能とその病態, Vol. 15: 105-112, 1998
  • Na<sup>+</sup>/グルコース共輸送体, No. 臨時増刊, p. 232-237, 1998
  • 機能を手がかりにしたクローニング, No. 臨時増刊, p. 66-70, 1998
  • トランスポーターの薬理, Vol. 42, p. 887-894, 1998
  • アミノ酸トランスポーターの構造・機能とその病態, Vol. 15, p. 105-112, 1998
  • アミノ酸交換輸送体, Vol. 44, p. 215-220, 1998
  • アミノ酸トランスポーターの構造・機能とその病態, Mebio, Vol. 15: 105-112, 1998
  • Na<sup>+</sup>/グルコース共輸送体, 腎と透析、1998臨時増刊号『分子腎臓病学』, No. 臨時増刊, p. 232-237, 1998
  • 機能を手がかりにしたクローニング, 腎と透析、1998臨時増刊号『分子腎臓病学』, No. 臨時増刊, p. 66-70, 1998
  • トランスポーターの薬理, 神経研究の進歩, Vol. 42, p. 887-894, 1998
  • アミノ酸トランスポーターの構造・機能とその病態, Vol. 15, p. 105-112, 1998
  • アミノ酸交換輸送体, 腎と透析, Vol. 44, p. 215-220, 1998
  • 有機アニオントランスポーター (OAT-1) のクローニング, Vol. 12, p. 291-291, 1997/10/09
  • Expression cloning from the rat kidney of multispecific organic anion transporter(PAH transporter) and the functional analysis., SEKINE TAKASHI,APIWATTANAKUL N,WATANABE NOBUAKI,HOSOYAMADA MAKOTO,KANAI YOSHIKATSU,ENDO HITOSHI, 生体膜と薬物の相互作用シンポジウム講演要旨集, Vol. 19th, p. 140-143, 1997/09
  • D-10 ラット腎ジカルボン酸トランスポーターのcDNAクローニング(一般口演,第25回杏林医学会総会), Vol. 28, No. 1, p. 127-128, 1997/03/31
  • 腎尿細管における糖輸送, No. 55増刊, p. 59-64, 1997
  • 腎尿細管における糖輸送, No. 55増刊, p. 59-64, 1997
  • 腎尿細管における糖輸送, 日本臨床『糖尿病(1)』, No. 55増刊, p. 59-64, 1997
  • Localization of the high affinity glutamate transporter EAAC1 in rat kidney, C Shayakul,Y Kanai,WS Lee,D Brown,JD Rothstein,MA Hediger, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, WILLIAMS & WILKINS, Vol. 7, No. 9, p. A0293-A0293, 1996/09
  • Structure, regulation and physiological roles of urea transporters, MA Hediger,CP Smith,GF You,WS Lee,Y Kanai,C Shayakul, KIDNEY INTERNATIONAL, BLACKWELL SCIENCE INC, Vol. 49, No. 6, p. 1615-1623, 1996/06
  • グルタミン酸トランスポーターの中枢神経系における機能的役割, Vol. 18, p. 435-441, 1996
  • Na<sup>+</sup>/アミノ酸共輸送蛋白, Vol. 54, p. 638-645, 1996
  • グルタミン酸トランスポータと筋萎縮性側索硬化症, Vol. 51, p. 64-70, 1996
  • グルタミン酸トランスポーターの中枢神経系における機能的役割, Vol. 18, p. 435-441, 1996
  • Na<sup>+</sup>/アミノ酸共輸送蛋白, Vol. 54, p. 638-645, 1996
  • グルタミン酸トランスポータと筋萎縮性側索硬化症, Vol. 51, p. 64-70, 1996
  • グルタミン酸トランスポーターの中枢神経系における機能的役割, 神経精神薬理, Vol. 18, p. 435-441, 1996
  • Na<sup>+</sup>/アミノ酸共輸送蛋白, 日本臨床, Vol. 54, p. 638-645, 1996
  • グルタミン酸トランスポータと筋萎縮性側索硬化症, 最新医学, Vol. 51, p. 64-70, 1996
  • D-28 神経細胞型およびグリア細胞型グルタミン酸トランスポーターのマウス脳からのcDNAクローニング(一般口演,第23回杏林医学会総会), Vol. 26, No. 1, 1995/03/31
  • アミノ酸、尿素トランスポータ, Vol. 50, p. 1997-2004, 1995
  • 尿素トランスポーター, Vol. 76, p. 347-352, 1995
  • ナトリウム共役トランスポーター, Vol. 32, p. 14-23, 1995
  • アミノ酸、尿素トランスポータ, Vol. 50, p. 1997-2004, 1995
  • 尿素トランスポーター, Vol. 76, p. 347-352, 1995
  • ナトリウム共役トランスポーター, Vol. 32, p. 14-23, 1995
  • アミノ酸、尿素トランスポータ, 最新医学, Vol. 50, p. 1997-2004, 1995
  • 尿素トランスポーター, 内科, Vol. 76, p. 347-352, 1995
  • ナトリウム共役トランスポーター, Vol. 32, p. 14-23, 1995
  • H+ COTRANSPORT IS COUPLED THE ELECTROGENIC OLIGOPEPTIDE TRANSPORTER, PEPT1, MF ROMERO,S NUSSBERGER,Y KANAI,MA HEDIGER,WF BORON, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 8, No. 4, p. A561-A561, 1994/03
  • 尿濃縮系-特に尿素輸送担体を中心に, Vol. 37, p. 25-30, 1994
  • グルタミン酸トランスポーター-その構造と機能, Vol. 12, p. 1465-1470, 1994
  • 尿濃縮系-特に尿素輸送担体を中心に, Vol. 37, p. 25-30, 1994
  • グルタミン酸トランスポーター-その構造と機能, Vol. 12, p. 1465-1470, 1994
  • 尿濃縮系-特に尿素輸送担体を中心に, 腎と透析, Vol. 37, p. 25-30, 1994
  • グルタミン酸トランスポーター-その構造と機能, 実験医学, Vol. 12, p. 1465-1470, 1994
  • CLONING AND CHARACTERIZATION OF HUMAN HIGH-AFFINITY GLUTAMATE TRANSPORTER CDNAS, M STELZNER,CP SMITH,Y KANAI,S KHAWAJA,PM BOUTIN,MA HEDIGER, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 7, No. 4, p. A575-A575, 1993/02
  • PRIMARY STRUCTURE AND FUNCTIONAL-CHARACTERIZATION OF A PUTATIVE NEURONAL HIGH-AFFINITY GLUTAMATE TRANSPORTER, Y KANAI,MA HEDIGER, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 7, No. 4, p. A636-A636, 1993/02
  • グルタミン酸トランスポーター-新しい神経伝達物質トランスポーターファミリーの確立, Vol. 11, p. 1748-1751, 1993
  • グルタミン酸トランスポーター-新しい神経伝達物質トランスポーターファミリーの確立, Vol. 11, p. 1748-1751, 1993
  • グルタミン酸トランスポーター-新しい神経伝達物質トランスポーターファミリーの確立, 実験医学, Vol. 11, p. 1748-1751, 1993
  • Mutations in SLC6A19 (hB0AT1) are Associated with the Hartnup disorder., Nature Genet, Vol. in press

Publications

  • プログレッシブ生命科学, 南山堂, ISBN:9784525134310, 2014
  • トランスポートソームの世界 : 膜輸送研究の源流から未来へ, 京都廣川書店, ISBN:9784901789660, 2011
  • 生体膜トランスポートソームの分子構築と生理機能, [金井好克], 2011
  • 神経伝達物質トランスポーター, 、Annual Review 神経 2000、後藤文男、高倉公朋、木下真男、柳澤信夫、清水輝夫編、中外医学社, 2000
  • アミノ酸トランスポーター:基質認識の多様性を生みだす分子基盤, シリーズ・ニューバイオフィジックス(]G0002[):「ポンプとトランスポーター」、共立出版, 2000
  • 神経伝達物質トランスポーター, Annual Review神経2000、中外医学社, 2000
  • 神経伝達物質トランスポーター, 、Annual Review 神経 2000、後藤文男、高倉公朋、木下真男、柳澤信夫、清水輝夫編、中外医学社, 2000
  • アミノ酸トランスポーター:基質認識の多様性を生みだす分子基盤, シリーズ・ニューバイオフィジックス(]G0002[):「ポンプとトランスポーター」、共立出版, 2000
  • 神経伝達物質トランスポーター, Annual Review神経2000、中外医学社, 2000
  • 神経伝達物質トランスポーター, 、Annual Review 神経 2000、後藤文男、高倉公朋、木下真男、柳澤信夫、清水輝夫編、中外医学社, 2000
  • アミノ酸トランスポーター:基質認識の多様性を生みだす分子基盤, シリーズ・ニューバイオフィジックス(]G0002[):「ポンプとトランスポーター」、共立出版, 2000
  • 神経伝達物質トランスポーター, Annual Review神経2000、中外医学社, 2000
  • グルタミン酸トランスポーター分子の機能と病態, グルタミン酸最新の話題、第2回神経伝達物質研究会記録集、金澤一郎編、 Excerpta Medica, 1999
  • グルタミン酸トランスポーター分子の機能と病態, グルタミン酸最新の話題、第2回神経伝達物質研究会話録集, 1999
  • グルタミン酸トランスポーター分子の機能と病態, グルタミン酸最新の話題、第2回神経伝達物質研究会記録集、金澤一郎編、 Excerpta Medica, 1999
  • グルタミン酸トランスポーター分子の機能と病態, グルタミン酸最新の話題、第2回神経伝達物質研究会話録集, 1999
  • グルタミン酸トランスポーター分子の機能と病態, グルタミン酸最新の話題、第2回神経伝達物質研究会記録集、金澤一郎編、 Excerpta Medica, 1999
  • グルタミン酸トランスポーター分子の機能と病態, グルタミン酸最新の話題、第2回神経伝達物質研究会話録集, 1999
  • アミノ酸トランスポーター, 最新内科学大系、プログレス10、腎・泌尿器科疾患、富田公夫編 中山書店, 1997
  • トランスポーター, 医系薬理学、遠藤仁、橋本敬太郎、後藤勝利編 中外医学社, 1997
  • 金井好克:アミノ酸トランスポータとその異常による疾患, 分子医科学で病気を識るシリーズ5:チャネルとトランスポータ-その働きと病気、岡田泰伸、清野進編 メジカルビュー社, 1997
  • グルタミン酸トランスポーター, BioScience 用語ライブラリー『脳神経』 御子柴克彦編 羊土社, 1997
  • アミノ酸トランスポーター, 最新内科学大系、プログレス10、腎・泌尿器科疾患、中山書店, 1997
  • トランスポーター, 医系薬理学、中外医学社, 1997
  • アミノ酸トランスポータとその異常による疾患, 分子医科学で病気を識るシリーズ5:チャネルとトランスポータ-その働きと病気、メジカルビュー社, 1997
  • グルタミン酸トランスポーター, Bio Science用語ライブラリー『脳神経』 羊土社, 1997
  • The high-affinity glutamate transporter family. In"Neurotransmitter transporters: Structure, function and regulation", M.E.A.Reith, Ed., Humana Press, Totowa,, 1997
  • The high-affinity glutamate trasporter family., In"Neurotransmitter transporters : Structure, function and regulation", Humana Press, Totowa, N. J., 1997
  • アミノ酸トランスポーター, 最新内科学大系、プログレス10、腎・泌尿器科疾患、富田公夫編 中山書店, 1997
  • トランスポーター, 医系薬理学、遠藤仁、橋本敬太郎、後藤勝利編 中外医学社, 1997
  • 金井好克:アミノ酸トランスポータとその異常による疾患, 分子医科学で病気を識るシリーズ5:チャネルとトランスポータ-その働きと病気、岡田泰伸、清野進編 メジカルビュー社, 1997
  • グルタミン酸トランスポーター, BioScience 用語ライブラリー『脳神経』 御子柴克彦編 羊土社, 1997
  • アミノ酸トランスポーター, 最新内科学大系、プログレス10、腎・泌尿器科疾患、中山書店, 1997
  • トランスポーター, 医系薬理学、中外医学社, 1997
  • アミノ酸トランスポータとその異常による疾患, 分子医科学で病気を識るシリーズ5:チャネルとトランスポータ-その働きと病気、メジカルビュー社, 1997
  • グルタミン酸トランスポーター, Bio Science用語ライブラリー『脳神経』 羊土社, 1997
  • アミノ酸トランスポーター, 最新内科学大系、プログレス10、腎・泌尿器科疾患、富田公夫編 中山書店, 1997
  • トランスポーター, 医系薬理学、遠藤仁、橋本敬太郎、後藤勝利編 中外医学社, 1997
  • 金井好克:アミノ酸トランスポータとその異常による疾患, 分子医科学で病気を識るシリーズ5:チャネルとトランスポータ-その働きと病気、岡田泰伸、清野進編 メジカルビュー社, 1997
  • グルタミン酸トランスポーター, BioScience 用語ライブラリー『脳神経』 御子柴克彦編 羊土社, 1997
  • アミノ酸トランスポーター, 最新内科学大系、プログレス10、腎・泌尿器科疾患、中山書店, 1997
  • トランスポーター, 医系薬理学、中外医学社, 1997
  • アミノ酸トランスポータとその異常による疾患, 分子医科学で病気を識るシリーズ5:チャネルとトランスポータ-その働きと病気、メジカルビュー社, 1997
  • グルタミン酸トランスポーター, Bio Science用語ライブラリー『脳神経』 羊土社, 1997
  • The high-affinity glutamate transporter family. In"Neurotransmitter transporters: Structure, function and regulation", M.E.A.Reith, Ed., Humana Press, Totowa,, 1997
  • The high-affinity glutamate trasporter family., In"Neurotransmitter transporters : Structure, function and regulation", Humana Press, Totowa, N. J., 1997
  • High-affinity glutamate trasporters : Physiological and pathological relevance in the the central nervous system., In"Excitatory amino acids : Their role in neuroendocrine function", CRC Press, Boca Raton, 1996
  • High-affinity glutamate trasporters : Physiological and pathological relevance in the the central nervous system., In"Excitatory amino acids : Their role in neuroendocrine function", CRC Press, Boca Raton, 1996
  • 腎特異有機溶質トランスポーターの構造と機能, Annual Review 腎臓, 中外医学社, 1995
  • 腎特異有機溶質トランスポーターの構造と機能, 腎臓1995,中外医学社, 1995
  • 腎特異有機溶質トランスポーターの構造と機能, Annual Review 腎臓, 中外医学社, 1995
  • 腎特異有機溶質トランスポーターの構造と機能, 腎臓1995,中外医学社, 1995
  • 腎特異有機溶質トランスポーターの構造と機能, Annual Review 腎臓, 中外医学社, 1995
  • 腎特異有機溶質トランスポーターの構造と機能, 腎臓1995,中外医学社, 1995
  • Identification of a new family of proteins involved in amino acid trasport., In : Molecular Biology and Function of Carrier Proteins. The Rockefeller University Press, New York, 1993
  • Identification of a new family of proteins involved in amino acid trasport., In : Molecular Biology and Function of Carrier Proteins. The Rockefeller University Press, New York, 1993

Industrial Property Rights

  • 芳香族アミノ酸誘導体およびそれを用いるPETプローブ, JP2014053100, 出願日:2014/02/10
  • フェノキシアルキルアミン化合物, JP2014051144, 出願日:2014/01/21
  • 膜貫通型タンパク質の質量分析方法および比較定量解析方法, 特願2012-037919, 出願日:2012/02/23
  • 膜貫通型タンパク質の質量分析方法および比較定量解析方法, 特許第5988238号, 特願2012-037919, 出願日:2012/02/23
  • 肝特異的有機アニオントランスポーターとその遺伝子, 特願2012-055037, 出願日:2012/03/12
  • アミノ酸輸送蛋白及びその遺伝子, 特願2010-264656, 出願日:2010/11/29
  • アミノ酸輸送蛋白及びその遺伝子, 特願2010-264655, 出願日:2010/11/29
  • アミノ酸輸送蛋白及びその遺伝子, 特許第5205440号, 特願2010-264656, 出願日:2010/11/29
  • アミノ酸輸送蛋白及びその遺伝子, 特許第4750222号, 特願2010-264655, 出願日:2010/11/29
  • 単一分子で機能する分枝鎖中性アミノ酸トランスポーター, 特願2010-117983, 出願日:2010/05/24
  • 単一分子で機能する分枝鎖中性アミノ酸トランスポーター, 特許第5281039号, 特願2010-117983, 出願日:2010/05/24
  • 新規抗CD98抗体, 特願2009-135435, 出願日:2009/06/04
  • 新規抗CD98抗体, 特許第5160501号, 特願2009-135435, 出願日:2009/06/04
  • 硫酸抱合体を選択的に輸送するトランスポーター及びその遺伝子, 特願2008-153720, 出願日:2008/06/12
  • LAT1阻害活性を有する芳香族アミノ酸誘導体、それを含有するLAT1阻害活性剤及びその製造方法, JP2006326233, 出願日:2006/12/28
  • 腎臓特異性を有する新規な有機イオントランスポーター, JP2006324117, 出願日:2006/12/01
  • 新規抗CD98抗体, JP2007057680, 出願日:2007/04/05
  • 中性アミノ酸トランスポーターによる癌の検出法、及びそのためのキット, 特願2004-076282, 出願日:2004/03/17
  • 中性アミノ酸トランスポーターによる癌の検出法、及びそのためのキット, 特許第4560314号, 特願2004-076282, 出願日:2004/03/17
  • 血管障害や高血圧症の治療・予防剤、及びそのスクリーニング方法, JP2004016761, 出願日:2004/11/11
  • 単一分子で機能する分枝鎖中性アミノ酸トランスポーター, JP2004002905, 出願日:2004/03/05
  • 硫酸抱合体を選択的に輸送するトランスポーター及びその遺伝子, 特願2002-070985, 出願日:2002/03/14
  • 酸性アミノ酸を輸送するナトリウム非依存性トランスポーター及びその遺伝子, 特願2002-040608, 出願日:2002/02/18
  • 酸性アミノ酸を輸送するナトリウム非依存性トランスポーター及びその遺伝子, 特許第4278906号, 特願2002-040608, 出願日:2002/02/18
  • 芳香族アミノ酸誘導体及び医薬組成物, JP2003001081, 出願日:2003/02/03
  • 小型中性アミノ酸を輸送するナトリウム非依存性トランスポーター及びその遺伝子、及びその機能特定を可能にした融合タンパク質作製によるトランスポーターの機能解析法, JP2002010143, 出願日:2002/09/30
  • 腎臓及び胎盤型尿酸トランスポーターとその遺伝子, 特願2001-290291, 出願日:2001/09/21
  • 腎臓及び胎盤型尿酸トランスポーターとその遺伝子, 特許第3824899号, 特願2001-290291, 出願日:2001/09/21
  • 精巣型カルニチントランスポーターとその遺伝子, JP2002005095, 出願日:2002/05/27
  • L−体及びD−体アミノ酸を輸送するナトリウム非依存性小型中性アミノ酸トランスポーター及びその遺伝子, 特願2000-028822, 出願日:2000/02/07
  • シスチン、塩基性アミノ酸及び中性アミノ酸を基質とするトランスポーター及びその遺伝子, 特願平11-223019, 出願日:1999/08/05
  • シスチン、塩基性アミノ酸及び中性アミノ酸を基質とするトランスポーター及びその遺伝子, 特許第4592131号, 特願平11-223019, 出願日:1999/08/05
  • 広い基質選択性を有する中性アミノ酸トランスポーター及びその遺伝子, 特願平11-158571, 出願日:1999/06/04
  • 広い基質選択性を有する中性アミノ酸トランスポーター及びその遺伝子, 特許第4326626号, 特願平11-158571, 出願日:1999/06/04
  • アミノ酸輸送蛋白及びその遺伝子, 特願平11-248546, 出願日:1999/09/02
  • アミノ酸輸送蛋白及びその遺伝子, 特許第4689781号, 特願平11-248546, 出願日:1999/09/02
  • 肝特異的有機アニオントランスポーターとその遺伝子, 特願平10-169174, 出願日:1998/06/03
  • 中性アミノ酸トランスポーター及びその遺伝子, 特願平10-126648, 出願日:1998/04/22
  • 中性アミノ酸トランスポーター及びその遺伝子, 特許第4157192号, 特願平10-126648, 出願日:1998/04/22
  • 有機陰イオントランスポーター及びその遺伝子, 特願平10-139411, 出願日:1998/05/21
  • 有機陰イオントランスポーター及びその遺伝子, 特許第4678899号, 特願平10-139411, 出願日:1998/05/21
  • フェノキシアルキルアミン化合物, 特許第6229896号, 特願2014-557541, 出願日:2014/01/21
  • 新規抗CD98抗体, 特許第4324637号, 特願2008-508722, 出願日:2007/04/05
  • 血管障害や高血圧症の治療・予防剤、及びそのスクリーニング方法, 特許第4660376号, 特願2005-515447, 出願日:2004/11/11
  • 単一分子で機能する分枝鎖中性アミノ酸トランスポーター, 特許第4660375号, 特願2005-503151, 出願日:2004/03/05
  • 芳香族アミノ酸誘導体及び医薬組成物, 特許第4705756号, 特願2003-565949, 出願日:2003/02/03
  • 小型中性アミノ酸を輸送するナトリウム非依存性トランスポーター及びその遺伝子、及びその機能特定を可能にした融合タンパク質作製によるトランスポーターの機能解析法, 特許第4161103号, 特願2003-532680, 出願日:2002/09/30
  • 精巣型カルニチントランスポーターとその遺伝子, 特許第4231778号, 特願2003-500253, 出願日:2002/05/27
  • 特許「中性アミノ酸トランスポーターによる癌の検出法、及びそのためのキット 」
  • 特許「血管障害や高血圧の治療・予防剤、及びそのスクリーニング法」
  • 特許「単一分子で機能する分枝鎖中性アミノ酸トランスポーター」
  • 特許「硫酸抱合体を選択的に輸送するトランスポーター及びその遺伝子」
  • 特許「芳香族L型アミノ酸誘導体及びL型アミノ酸トランスポーター阻害剤」
  • 特許「酸性アミノ酸を輸送するナトリウム非依存性トランスポーター及びその遺伝子」
  • 特許「腎臓特異尿酸トランスポーターとその遺伝子」
  • 特許「腎臓及び胎盤型尿酸トランスポーターとその遺伝子」
  • 特許「精巣型カルニチントランスポーターとその遺伝子」
  • 特許「小型中性アミノ酸と輸送するナトリウム非依存性トランスポーター及びその遺伝子、及びその機能特定を可能にした融合タンパク質作製によるトランスポーターの機能解析法」
  • 特許「脳型有機アニオントランスポーターとその遺伝子」
  • 特許「アミノ酸輸送蛋白及びその遺伝子」
  • 特許「肝特異的有機アニオントランスポーターとその遺伝子」
  • 特許「有機イオントランスポーター及びその遺伝子」
  • 特許「L-体及びD-体アミノ酸を輸送するナトリウム非依存性小型中性アミノ酸トランスポーター及びその遺伝子」
  • 特許「シスチン、塩基性アミノ酸及び中性アミノ酸を基質とするトランスポーター及びその遺伝子」
  • 特許「広い基質選択性を有する中性アミノ酸トランスポーター及びその遺伝子」
  • 特許「アミノ酸輸送蛋白及びその遺伝子」
  • 特許「中性アミノ酸トランスポーター及びその遺伝子」
  • 特許「有機陰イオントランスポーター及びその遺伝子」

Awards

  • Highly Cited Researcher-2020, 2020/11
  • 第3回 日本医療研究開発大賞 内閣総理大臣賞, 2020/01
  • 第3回 大阪大学総長顕彰, 2014
  • 第2回 大阪大学総長顕彰, 2013
  • 第7回 江橋節郎賞, 2013
  • 分子腎臓研究会最優秀研究奨励賞, 2000
  • 分子腎臓研究会優秀研究奨励賞, 1998
  • 日本薬物動態学会ベストポスター賞, 1997
  • 研究奨励賞(持田医学薬学振興財団), 1996
  • 平成7年度最優秀研究(文部科学省重点領域研究「チャネルとトランスポーターの構造・機能協関, 1996
  • 分子腎臓研究会最優秀研究奨励賞, 1995
  • Award from International Academy for Biomedical and Drug Research in 1994: Special Recognition of Excellence., 1994

Presentations

  • 特別講演「アミノ酸トランスポーターLAT1を標的とした創薬」, 2019/11/14
  • Renal cystine transporters and epithelial transport disorders, KANAI Yoshikatsu, 11th BioMedical Transporters Conference, 2019/08/07
  • 特別講演「アミノ酸輸送系を利用したがん特異的化合物送達-LAT1, LAT2によるPETプローブとBNCTホウ素化合物の評価-」, 2019/06/27
  • Special Lecture "Development of anti-tumor drugs targeting amino acid transporters in cancers", KANAI Yoshikatsu, 22nd Japan-Korea Joint Seminar on Pharmacology, 2019/03/16
  • 腫瘍細胞型アミノ酸トランスポーターリガンドの構造活性相関から見えてくる創薬標的としての意義, 2017/03/16
  • SGLT2阻害薬の作用メカニズムと多面的な作用, 2017/03/09
  • SGLT2阻害薬:新たな糖尿病治療薬として作用とメカニズム, 2017/03/05
  • Amino acid transporter LAT1 as a novel molecular target for cancer diagnosis and therapeutics, 2017/02/24
  • Pharmacology to innovative drug development: cancer therapeutics and diagnosis targeting amino acid transporters, 2017/02/16
  • がん細胞型アミノ酸トランスポーターを標的とした新規作用機序の抗悪性腫瘍薬と汎用性の高いがん特異的PETプロープの開発, 2017/02/13
  • SGLT2と腎グルコース再吸収の基礎, 2016/11/09
  • SGLT2阻害薬の基礎, 2016/10/07
  • 特別講演「がん細胞アミノ酸トランスポーターを標的としたがんの検出と細胞活性制御」, 2016/09/16
  • SGLT2のスクリーニングからSGLT2阻害薬の創薬・臨床, 2016/09/05
  • Special Lecture “Amino acid transporters as targets for cancer-selective drug delivery and anti-cancer therapeutics”, KANAI Yoshikatsu, 2nd Drug Transporters Forum, 2016/07/23
  • Special Lecture "Transporter and urolithiasis", 2016/07/20
  • トランスポーターを標的とした創薬, 2016/07/06
  • 特別講演「栄養素トランスポーターを標的とした病態代謝制御:SGLT2阻害薬の最近の知見とアミノ酸・有機酸トランスポーターの創薬標的としての可能性」, 2016/07/02