日本薬理学会評議員
2020/04 - Present
日本薬学会薬理系薬学部会若手世話人
2019/08 - Present
第96回日本薬理学会年会 プログラム委員 Academic society
2022/03 - 2022/12
日本腎臓学会基礎研究推進小委員会委員
2018/04 - 2020/03
大阪大学大学院薬学研究科X線作業主任者
大阪大学大学院薬学研究科放射線取扱主任者
日本薬理学会
日本循環薬理学会
日本腎臓学会
日本薬学会
Life sciences / Nephrology /
日本薬学会薬理系薬学部会 生体機能と創薬シンポジウム2023優秀発表賞
2023/08
令和4年度大阪大学沢井記念薬友会賞研究部門賞
2023/03
優秀演題賞
尾花理徳 第29回日本循環薬理学会第55回高血圧関連疾患モデル学会合同学会 2019/11
Young Investigator Award
尾花理徳 第29回日本循環薬理学会 2019/11
Fatty acid metabolism suppresses neonatal cardiomyocyte proliferation by increasing PDK4 and HMGCS2 expression through PPARδ
Tanaka S., Hirota A., Okada Y., Obana M., Fujio Y.
PLoS One Vol. 20 No. 5 2025/05 Research paper (scientific journal)
Application of one-class classification using deep learning technique improves the classification of subvisible particles
Nakae T., Maruyama S., Ogawa T., Hasegawa S., Obana M., Fujio Y.
Journal of Pharmaceutical Sciences Vol. 114 No. 2 p. 1117-1124 2025/02 Research paper (scientific journal)
Suppression of Dad1 induces cardiomyocyte death by weakening cell adhesion.
Shota Mori, Rumi Kimura, Hirofumi Morihara, Masashi Tomimatsu, Shota Fuchigami, Kotaro Matsumoto, Shota Tanaka, Yoshiaki Okada, Makiko Maeda, Masanori Obana, Yasushi Fujio
American journal of physiology. Cell physiology 2024/11/29 Research paper (scientific journal)
Endothelial ROBO4 suppresses PTGS2/COX-2 expression and inflammatory diseases.
Masato Tanaka, Keisuke Shirakura, Yui Takayama, Miki Μatsui, Yukio Watanabe, Takuya Yamamoto, Junya Takahashi, Shota Tanaka, Nobumasa Hino, Takefumi Doi, Masanori Obana, Yasushi Fujio, Kazuo Takayama, Yoshiaki Okada
Communications biology Vol. 7 No. 1 p. 599-599 2024/05/18 Research paper (scientific journal)
JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice.
Hibiki Sakai, Hiroyasu Kamuro, Nagisa Tokunoh, Takeshi Izawa, Shigeyuki Tamiya, Ayaha Yamamoto, Shota Tanaka, Daisuke Okuzaki, Chikako Ono, Yoshiharu Matsuura, Yoshiaki Okada, Yasuo Yoshioka, Yasushi Fujio, Masanori Obana
American journal of physiology. Renal physiology Vol. 326 No. 6 p. F931-F941 2024/04/18 Research paper (scientific journal)
Cardioprotective effect of Interleukin-11 against warm ischemia-reperfusion injury in a rat heart donor model.
Tomoki Sakata, Hiroki Kohno, Tomohiko Inui, Hiroki Ikeuchi, Yuki Shiko, Yohei Kawasaki, Shota Suzuki, Shota Tanaka, Masanori Obana, Kiyotake Ishikawa, Yasushi Fujio, Goro Matsumiya
European journal of pharmacology Vol. 961 p. 176145-176145 2023/12/15 Research paper (scientific journal)
Runx1 is upregulated by STAT3 and promotes proliferation of neonatal rat cardiomyocytes.
Shota Suzuki, Shota Tanaka, Yusuke Kametani, Ayaka Umeda, Kosuke Nishinaka, Kaho Egawa, Yoshiaki Okada, Masanori Obana, Yasushi Fujio
Physiological reports Vol. 11 No. 23 2023/12 Research paper (scientific journal)
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models.
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada
Proceedings of the National Academy of Sciences of the United States of America Vol. 120 No. 3 2023/01/17 Research paper (scientific journal)
Arid5a/IL-6/PAI-1 Signaling Is Involved in the Pathogenesis of Lipopolysaccharide-Induced Kidney Injury.
Koki Tanaka, Hiroki Harada, Hiroyasu Kamuro, Hibiki Sakai, Ayaha Yamamoto, Masashi Tomimatsu, Akari Ikeda, Renya Chosokabe, Shota Tanaka, Yoshiaki Okada, Yasushi Fujio, Masanori Obana
Biological & pharmaceutical bulletin Vol. 46 No. 12 p. 1753-1760 2023 Research paper (scientific journal)
Myeloid-derived suppressor cells exacerbate poly(I:C)-induced lung inflammation in mice with renal injury and older mice.
Zhiqi Xie, Haoyang Zhou, Masanori Obana, Yasushi Fujio, Naoki Okada, Masashi Tachibana
Frontiers in immunology Vol. 14 p. 1243851-1243851 2023 Research paper (scientific journal)
Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling
Masashi Tomimatsu, Kotaro Matsumoto, Moe Ashizuka, Shohei Kumagai, Shota Tanaka, Takafumi Nakae, Kosei Yokota, Shunsuke Kominami, Ryota Kajiura, Daisuke Okuzaki, Daisuke Motooka, Aki Shiraishi, Takaya Abe, Hideo Matsuda, Yoshiaki Okada, Makiko Maeda, Shigeto Seno, Masanori Obana, Yasushi Fujio
Scientific Reports Vol. 12 No. 1 p. 16656-16656 2022/10/05 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.
Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, Risa Funatsu, Kaori Kosugi, Sayaka Deguchi, Masaki Yamamoto, Yugo Tsunoda, Maaya Morita, Kosuke Muraoka, Masato Tanaka, Tomoaki Kanbara, Shota Tanaka, Shigeyuki Tamiya, Nagisa Tokunoh, Atsushi Kawai, Masahito Ikawa, Chikako Ono, Keisuke Tachibana, Masuo Kondoh, Masanori Obana, Yoshiharu Matsuura, Akihiro Ohsumi, Takeshi Noda, Takuya Yamamoto, Yasuo Yoshioka, Yu-Suke Torisawa, Hiroshi Date, Yasushi Fujio, Miki Nagao, Kazuo Takayama, Yoshiaki Okada
Science advances Vol. 8 No. 38 2022/09/23 Research paper (scientific journal)
Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis
Yoshiaki Miyake, Masanori Obana, Ayaha Yamamoto, Shunsuke Noda, Koki Tanaka, Hibiki Sakai, Narihito Tatsumoto, Chihiro Makino, Soshi Kanemoto, Go Shioi, Shota Tanaka, Makiko Maeda, Yoshiaki Okada, Kazunori Imaizumi, Katsuhiko Asanuma, Yasushi Fujio
Communications Biology Vol. 5 No. 1 p. 734-734 2022/07/22 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
Glycoprotein 130 orchestrates signal transduction network to promote cardiomyocyte proliferation for normal growth
Masanori Obana, Makiko Maeda, Yasushi Fujio
American Journal of Physiology-Heart and Circulatory Physiology Vol. 323 No. 1 p. H125-H127 2022/07/01 Research paper (scientific journal)
Publisher: American Physiological Society
CXCL10 is a novel anti-angiogenic factor downstream of p53 in cardiomyocytes.
Tri Wahyuni, Shota Tanaka, Ryuta Igarashi, Yoshiaki Miyake, Ayaha Yamamoto, Shota Mori, Yusuke Kametani, Masashi Tomimatsu, Shota Suzuki, Kosei Yokota, Yoshiaki Okada, Makiko Maeda, Masanori Obana, Yasushi Fujio
Physiological reports Vol. 10 No. 9 2022/05 Research paper (scientific journal)
Yes‐associated protein activation potentiates glycogen synthase kinase‐3 inhibitor‐induced proliferation of neonatal cardiomyocytes and iPS cell‐derived cardiomyocytes
Yusuke Kametani, Shota Tanaka, Yuriko Wada, Shota Suzuki, Ayaka Umeda, Kosuke Nishinaka, Yoshiaki Okada, Makiko Maeda, Shigeru Miyagawa, Yoshiki Sawa, Masanori Obana, Yasushi Fujio
Journal of Cellular Physiology 2022/03/21 Research paper (scientific journal)
Publisher: Wiley
Identification of biomarkers of chronic kidney disease among kidney-derived proteins
Kazuma Higashisaka, Sonoko Takeya, Haruhiko Kamada, Masanori Obana, Makiko Maeda, Mai Kabayama, Koichi Yamamoto, Nanan Ishida, Ryo Isaka, Hirofumi Tsujino, Kazuya Nagano, Noriyuki Tomiyama, Hiromi Rakugi, Yasushi Fujio, Kei Kamide, Yasuo Tsutsumi
Clinical Proteomics Vol. 19 No. 1 2022/01 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
PKNOX2 regulates myofibroblast functions and tubular cell survival during kidney fibrosis
Yoshiaki Miyake, Masanori Obana, Takafumi Nakae, Ayaha Yamamoto, Shota Tanaka, Makiko Maeda, Yoshiaki Okada, Yasushi Fujio
Biochemical and Biophysical Research Communications Vol. 571 p. 88-95 2021/09 Research paper (scientific journal)
Publisher: Elsevier BV
Title: Gene transfer by pyro-drive jet injector is a novel therapeutic approach for muscle diseases
Takafumi Nakae, Masanori Obana, Takahiro Maeda, Akari Ikeda, Hiroshi Miyazaki, Shota Tanaka, Makiko Maeda, Kunihiko Yamashita, Kazuhiro Terai, Satoshi Obika, Yasushi Fujio
Gene Vol. 788 p. 145664-145664 2021/07 Research paper (scientific journal)
Publisher: Elsevier BV
Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway
Tri Wahyuni, Arisa Kobayashi, Shota Tanaka, Yoshiaki Miyake, Ayaha Yamamoto, Anton Bahtiar, Shota Mori, Yusuke Kametani, Masashi Tomimatsu, Kotaro Matsumoto, Makiko Maeda, Masanori Obana, Yasushi Fujio
American Journal of Physiology-Cell Physiology Vol. 321 No. 1 2021/05/26 Research paper (scientific journal)
Publisher: American Physiological Society
Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis.
Ayaha Yamamoto, Hitomi Morioki, Takafumi Nakae, Yoshiaki Miyake, Takeo Harada, Shunsuke Noda, Sayuri Mitsuoka, Kotaro Matsumoto, Masashi Tomimatsu, Soshi Kanemoto, Shota Tanaka, Makiko Maeda, Simon J Conway, Kazunori Imaizumi, Yasushi Fujio, Masanori Obana
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Vol. 35 No. 2 2021/02 Research paper (scientific journal)
Activation of YAP is essential for the myocardial recovery from myocarditis
Fukuyama Shoki, Kametani Yusuke, Wada Yuriko, Suzuki Shota, Umeda Ayaka, Maeda Makiko, Tanaka Shota, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 94 2021
Publisher: Japanese Pharmacological Society
Acute kidney injury-induced ZBTB38 contributes to tubular cell loss.
Harada Takeo, Obana Masanori, Miyake Yosiaki, Yamamoto Ayaha, Kamuro Hiroyasu, Tanaka Syota, Maeda Makiko, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 94 2021
Publisher: Japanese Pharmacological Society
Establishment of a novel experimental autoimmune vasculitis model
Seo Takafumi, Tanaka Shota, Maeda Makiko, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 94 2021
Publisher: Japanese Pharmacological Society
Cardioprotective roles of novel cell death inhibitor, defender against cell death 1 (Dad1)
Mori Shota, Tanaka Shota, Maeda Makiko, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 94 2021
Publisher: Japanese Pharmacological Society
β2-adrenergic stimulation induces interleukin-6 by increasing Arid5a, a stabilizer of mRNA, through cAMP/PKA/CREB pathway in cardiac fibroblasts.
Tanaka S, Imaeda A, Matsumoto K, Maeda M, Obana M, Fujio Y.
Pharmacology Research and Perspectives Vol. 8 No. 2 2020/04 Research paper (scientific journal)
Inhibition of transcription factor OASIS attenuated kidney fibrosis
Yamamoto Ayaha, Obana Masanori, Nakae Takafumi, Miyake Yoshiaki, Mitsuoka Sayuri, Maeda Makiko, Imaizumi Kazunori, Matsumoto Kotaro, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 93 2020
Publisher: Japanese Pharmacological Society
Development of a screening system for the compounds that induce the cell cycle activity in mammalian cardiomyocytes
Matsui Risa, Fukuyama Shoki, Kametani Yusuke, Wada Yuriko, Matsumoto Kotaro, Maeda Makiko, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 93 2020
Publisher: Japanese Pharmacological Society
Dad1 inhibits cardiomyocyte death by promoting cell adhesion
Shota Mori, Kimura Rumi, Fuchigami Shota, Matsumoto Kotaro, Maeda Makiko, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 93 2020
Publisher: Japanese Pharmacological Society
β2 adrenergic signaling of cardiac fibroblasts induces cardiac hypertrophy through paracrine system
Imaeda Atsuki, Tanaka Shota, Matsumoto Kotaro, Maeda Makiko, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 93 2020
Publisher: Japanese Pharmacological Society
β2-adrenergic stimulation induces Arid5a through cAMP/PKA/CREB axis to promote IL-6 upregulation
Tanaka Shota, Imaeda Atsuki, Matsumoto Kotaro, Maeda Makiko, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 93 2020
Publisher: Japanese Pharmacological Society
Blockade of NKG2D/NKG2D ligand interaction attenuated cardiac remodelling after myocardial infarction.
Kotaro Matsumoto, Masanori Obana, Arisa Kobayashi, Miho Kihara, Go Shioi, Shigeru Miyagawa, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yoshiki Sawa, Yasushi Fujio
Cardiovascular research Vol. 115 No. 4 p. 765-775 2019/03 Research paper (scientific journal)
Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice.
Atsuki Imaeda, Shota Tanaka, Kota Tonegawa, Shota Fuchigami, Masanori Obana, Makiko Maeda, Miho Kihara, Hiroshi Kiyonari, Simon J Conway, Yasushi Fujio, Hiroyuki Nakayama
Biochemical and biophysical research communications Vol. 510 No. 1 p. 149-155 2019/02 Research paper (scientific journal)
Inhibition of OASIS in podocytes suppressed diabetes-induced kidney dysfunction
Miyake Yoshiaki, Obana Masanori, Yamamoto Ayaha, Noda Shunsuke, Kanemoto Soshi, Maeda Makiko, Asanuma Katsuhiko, Imaizumi Kazunori, Nakayama Hiroyuki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 92 2019
Publisher: Japanese Pharmacological Society
Characterization of mononuclear cardiomyocytes in adult murine hearts
Nakayasu Yusuke, Matsui Risa, Fukuyama Shoki, Kametani Yusuke, Wada Yuriko, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 92 2019
Publisher: Japanese Pharmacological Society
Suppression of Defender against cell death 1 leads to cardiomyocyte death
Fuchigami Shota, Kimura Rumi, Matumoto Kotaro, Morihara Hirofumi, Mori Shota, Obana Masonori, Maeda Makiko, Fujio Yasushi, Nakayama Hiroyuki
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 92 2019
Publisher: Japanese Pharmacological Society
Comprehensive search for cardiomyocyte death-related genes using forward genetic screening
Nakayama Nami, Seo Takafumi, Obana Masanori, Maeda Makiko, Fujio Yasushi, Nakayama Hiroyuki
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 92 2019
Publisher: Japanese Pharmacological Society
The overexpression of CGRRF1 induces hypertrophy in cultured cardiomyocytes
Kinoshita Maki, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 92 2019
Publisher: Japanese Pharmacological Society
Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer.
Takuya Shintani, Kazuma Higashisaka, Makiko Maeda, Masaya Hamada, Ryosuke Tsuji, Koudai Kurihara, Yuri Kashiwagi, Atsuhiro Sato, Masanori Obana, Ayaha Yamamoto, Keisuke Kawasaki, Ying Lin, Takashi Kijima, Yuhei Kinehara, Yoshihiro Miwa, Shinichiro Maeda, Eiichi Morii, Atsushi Kumanogoh, Yasuo Tsutsumi, Izumi Nagatomo, Yasushi Fujio
Oncotarget Vol. 9 No. 101 p. 37520-37533 2018/12/25 Research paper (scientific journal)
Sustained Activation of Guanylate Cyclase-A with TDT, a Natriuretic Peptide Derivative, Exhibits Cardiorenal Protection in Dahl Salt-Sensitive Hypertensive Rats
Shohei Oishi, Naoko Suzuki, Yuri Hasui, Tsuyoshi Homma, Masanori Obana, Takahiro Nagayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Vol. 363 No. 3 p. 402-410 2017/12 Research paper (scientific journal)
2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice
Hirofumi Morihara, Masanori Obana, Shota Tanaka, Ikki Kawakatsu, Daisuke Tsuchiyama, Shota Mori, Hiroshi Suizu, Akiko Ishida, Rumi Kimura, Izuru Tsuchimochi, Makiko Maeda, Takehiko Yoshimitsu, Yasushi Fujio, Hiroyuki Nakayama
PLoS ONE Vol. 12 No. 12 2017/12/01 Research paper (scientific journal)
Publisher: Public Library of Science
RORγt-expressing cells attenuate cardiac remodeling after myocardial infarction
Daichi Enomoto, Kotaro Matsumoto, Tomomi Yamashita, Arisa Kobayashi, Makiko Maeda, Hiroyuki Nakayama, Masanori Obana, Yasushi Fujio
PLOS ONE Vol. 12 No. 8 p. e0183584-e0183584 2017/08/21 Research paper (scientific journal)
Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis
Akimitsu Miyawaki, Masanori Obana, Yusuke Mitsuhara, Aya Orimoto, Yusuke Nakayasu, Tomomi Yamashita, So-ichiro Fukada, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
SCIENTIFIC REPORTS Vol. 7 2017/05 Research paper (scientific journal)
Mouse model of Epstein-Barr virus LMP1-and LMP2A-driven germinal center B-cell lymphoproliferative disease
Takeharu Minamitani, Yijie Ma, Hufeng Zhou, Hiroshi Kida, Chao-Yuan Tsai, Masanori Obana, Daisuke Okuzaki, Yasushi Fujio, Atsushi Kumanogoh, Bo Zhao, Hitoshi Kikutani, Elliott Kieff, Benjamin E. Gewurz, Teruhito Yasui
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 114 No. 18 p. 4751-4756 2017/05 Research paper (scientific journal)
Phospholamban Inhibition by a Single Dose of Locked Nucleic Acid Antisense Oligonucleotide Improves Cardiac Contractility in Pressure Overload-Induced Systolic Dysfunction in Mice
Hirofumi Morihara, Tsuyoshi Yamamoto, Harunori Oiwa, Kota Tonegawa, Daisuke Tsuchiyama, Ikki Kawakatsu, Masanori Obana, Makiko Maeda, Tomomi Mohri, Satoshi Obika, Yasushi Fujio, Hiroyuki Nakayama
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS Vol. 22 No. 3 p. 273-282 2017/05 Research paper (scientific journal)
Caveolae-specific activation loop between CaMKII and L-type Ca2+ channel aggravates cardiac hypertrophy in alpha(1)-adrenergic stimulation
Kota Tonegawa, Wataru Otsuka, Shohei Kumagai, Sachi Matsunami, Nao Hayamizu, Shota Tanaka, Kazumasa Moriwaki, Masanori Obana, Makiko Maeda, Michio Asahi, Hiroshi Kiyonari, Yasushi Fujio, Hiroyuki Nakayama
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY Vol. 312 No. 3 p. H501-H514 2017/03 Research paper (scientific journal)
Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates cytoskeletal reorganization with protrusion formation
Akimitsu Miyawaki, Yusuke Mitsuhara, Aya Orimoto, Yusuke Nakayasu, Shin-ichi Tsunoda, Masanori Obana, Makiko Maeda, Hiroyuki Nakayama, Yasuo Yoshioka, Yasuo Tsutsumi, Yasushi Fujio
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY Vol. 311 No. 2 p. H476-H486 2016/08 Research paper (scientific journal)
Myeloid cell-derived LRG attenuates adverse cardiac remodelling after myocardial infarction
Shohei Kumagai, Hiroyuki Nakayama, Minoru Fujimoto, Hiromi Honda, Satoshi Serada, Hatsue Ishibashi-Ueda, Atsushi Kasai, Masanori Obana, Yasushi Sakata, Yoshiki Sawa, Yasushi Fujio, Tetsuji Naka
CARDIOVASCULAR RESEARCH Vol. 109 No. 2 p. 272-282 2016/02 Research paper (scientific journal)
Interleukin-27 induces the endothelial differentiation in Sca-1+cardiac resident stem cells
Tomohiro Tanaka, Masanori Obana, Tomomi Mohri, Masaki Ebara, Yuta Otani, Makiko Maeda, Yasushi Fujio
CYTOKINE Vol. 75 No. 2 p. 365-372 2015/10 Research paper (scientific journal)
Cardiac-specific ablation of the STAT3 gene in the subacute phase of myocardial infarction exacerbated cardiac remodeling
Daichi Enomoto, Masanori Obana, Akimitsu Miyawaki, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY Vol. 309 No. 3 p. H471-H480 2015/08 Research paper (scientific journal)
Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart
Masanori Obana, Kaori Miyamoto, Shiho Murasawa, Tomohiko Iwakura, Akiko Hayama, Tomomi Yamashita, Momoko Shiragaki, Shohei Kumagai, Akimitsu Miyawaki, Kana Takewaki, Goro Matsumiya, Makiko Maeda, Minoru Yoshiyama, Hiroyuki Nakayama, Yasushi Fujio
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY Vol. 303 No. 5 p. H569-H577 2012/09 Research paper (scientific journal)
Glycoprotein 130 Cytokine Signal as a Therapeutic Target Against Cardiovascular Diseases
Yasushi Fujio, Makiko Maeda, Tomomi Mohri, Masanori Obana, Tomohiko Iwakura, Akiko Hayama, Tomomi Yamashita, Hiroyuki Nakayama, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 117 No. 4 p. 213-222 2011/12
IL-6-mediated Th17 differentiation through ROR gamma t is essential for the initiation of experimental autoimmune myocarditis
Tomomi Yamashita, Tomohiko Iwakura, Kazuki Matsui, Haruyo Kawaguchi, Masanori Obana, Akiko Hayama, Makiko Maeda, Yasukatsu Izumi, Issei Komuro, Yoshiyuki Ohsugi, Minoru Fujimoto, Tetsuji Naka, Tadamitsu Kishimoto, Hiroyuki Nakayama, Yasushi Fujio
CARDIOVASCULAR RESEARCH Vol. 91 No. 4 p. 640-648 2011/09 Research paper (scientific journal)
STAT3/Pim-1 signaling pathway plays a crucial role in endothelial differentiation of cardiac resident Sca-1+cells both in vitro and in vivo
Tomohiko Iwakura, Tomomi Mohri, Tatsuto Hamatani, Masanori Obana, Tomomi Yamashita, Makiko Maeda, Naoto Katakami, Hideaki Kaneto, Toru Oka, Issei Komuro, Junichi Azuma, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 51 No. 2 p. 207-214 2011/08 Research paper (scientific journal)
Therapeutic Activation of Signal Transducer and Activator of Transcription 3 by Interleukin-11 Ameliorates Cardiac Fibrosis After Myocardial Infarction
Masanori Obana, Makiko Maeda, Koji Takeda, Akiko Hayama, Tomomi Mohri, Tomomi Yamashita, Yoshikazu Nakaoka, Issei Komuro, Kiyoshi Takeda, Goro Matsumiya, Junichi Azuma, Yasushi Fujio
CIRCULATION Vol. 121 No. 5 p. 684-U121 2010/02 Research paper (scientific journal)
Signals Through Glycoprotein 130 Regulate the Endothelial Differentiation of Cardiac Stem Cells
Tomomi Mohri, Yasushi Fujio, Masanori Obana, Tomohiko Iwakura, Koichi Matsuda, Makiko Maeda, Junichi Azuma
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 29 No. 5 p. 754-760 2009/05 Research paper (scientific journal)
Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes
Yasuhiro Yamamoto, Yuki Hoshino, Takashi Ito, Tetsuro Nariai, Tomomi Mohri, Masanori Obana, Nozomi Hayata, Yoriko Uozumi, Makiko Maeda, Yasushi Fujio, Junichi Azuma
CARDIOVASCULAR RESEARCH Vol. 79 No. 1 p. 89-96 2008/07 Research paper (scientific journal)
Connective tissue growth factor induces cardiac hypertrophy through Akt signaling
Nozomi Hayata, Yasushi Fujio, Yasuhiro Yamamoto, Tomohiko Iwakura, Masanori Obana, Mika Takai, Tomomi Mohri, Shinpei Nonen, Makiko Maeda, Junichi Azuma
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 370 No. 2 p. 274-278 2008/05 Research paper (scientific journal)
Identification of cardiac myocytes as the target of interleukin 11, a cardioprotective cytokine
Ryusuke Kimura, Makiko Maeda, Atsushi Arita, Yuichi Oshima, Masanori Obana, Takashi Ito, Yasuhiro Yamamoto, Tomorm Mohri, Tadamitsu Kishimoto, Ichiro Kawase, Yasushi Fujio, Junichi Azuma
CYTOKINE Vol. 38 No. 2 p. 107-115 2007/05 Research paper (scientific journal)
SARS-CoV-2感染初期におけるJAK阻害はマウスにおいて内因性抗ウイルス活性の低下とともに腎障害を悪化させる(JAK inhibition in the early phase of SARS-CoV-2 infection exacerbates kidney injury along with decreased endogenous antiviral activity in mice)
尾花 理徳, 坂井 響, 禿 宏保, 徳納 渚沙, 山本 彩葉, 岡田 欣晃, 吉岡 靖雄, 藤尾 慈
日本腎臓学会誌 Vol. 66 No. 4 p. 610-610 2024/06
Publisher: (一社)日本腎臓学会SARS-CoV-2感染初期におけるJAK阻害剤投与は腎障害を悪化させる
坂井響, 尾花理徳, 禿宏保, 徳納渚沙, 山本彩葉, 岡田欣晃, 吉岡靖雄, 藤尾慈
次世代を担う若手のための創薬・医療薬理シンポジウムプログラム・要旨集 Vol. 2023 2023
液体クロマトグラフィータンデム質量分析法による梗塞後心筋組織における脂質メディエーターの発現の検討
米田直万, 田中翔大, 尾花理徳, 尾花理徳, 岡田欣晃, 藤尾慈, 藤尾慈
日本薬理学雑誌 Vol. 158 No. Supplement 2023
成体マウス心臓において,YAPの活性化は,心筋炎による組織傷害からの修復に必須である
梅田綾香, 亀谷祐介, 鈴木翔大, 西中康介, 江川果穂, 田中翔大, 岡田欣晃, 尾花理徳, 尾花理徳, 藤尾慈, 藤尾慈
日本臨床薬理学会学術総会抄録集(Web) Vol. 44th 2023
抗IL-6受容体抗体およびJAK阻害剤がSARS-CoV-2感染後腎障害に与える影響解明-非臨床モデルを用いた解析-
禿宏保, 尾花理徳, 坂井響, 徳納渚沙, 山本彩葉, 田中翔大, 岡田欣晃, 吉岡靖雄, 藤尾慈
日本臨床薬理学会学術総会抄録集(Web) Vol. 44th 2023
YAPシグナルは,GSK3-βcateninシグナルによる心筋細胞増殖誘導を増強する
亀谷祐介, 鈴木翔大, 梅田綾香, 西中康介, 田中翔大, 岡田欣晃, 尾花理徳, 藤尾慈
次世代を担う若手のための創薬・医療薬理シンポジウムプログラム・要旨集 Vol. 2022 2022
Exhaustive exploration of novel factors related to cardiomyocyte proliferation using the cell cycle-sensitive protein FUCCI
Wada Yuriko, Kametani Yusuke, Suzuki Shota, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 95 2022
Publisher: Japanese Pharmacological Society
Endogenous YAP activity potentiates GSK3 inhibitors-induced proliferation of cardiomyocytes.
Kametani Yusuke, Suzuki Shota, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 95 2022
Publisher: Japanese Pharmacological Society
Increased OASIS in podocytes contributes to the disruption of kidney homeostasis
Miyake Yoshiaki, Obana Masanori, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Imaizumi Kazunori, Asanuma Katsuhiko, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 95 2022
Publisher: Japanese Pharmacological Society
IL-6 family cytokines, STAT3 activators, exhibit differential effects in a ligand-specific manner in podocytes
Sayuri Mitsuoka, Obana Masanori, Miyake Yoshiaki, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 95 2022
Publisher: Japanese Pharmacological Society
TGFβ3 exacerbates myocardial remodeling after myocardial infarction.
Tomimatsu Masashi, Yokota Kosei, Kominami Shunsuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 95 2022
Publisher: Japanese Pharmacological Society
Leupaxin is upregulated in fibrotic kidneys and contributes to the proliferation of kidney fibroblasts
Noda Shunsuke, Obana Masanori, Miyake Yoshiaki, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 95 2022
Publisher: Japanese Pharmacological Society
Establishment of a novel method for analysis of biological functions of myeloid cell subpopulation in cardiovascular diseases using TRECK system.
Yokota Kosei, Tomimatsu Masashi, Kominami Shunsuke, Kajiura Ryota, Tanaka Shota, Obana Masanori, Okada Yoshiaki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 96 2022
Publisher: Japanese Pharmacological Society
Runx1 is upregulated by STAT3 and promotes cell proliferation in neonatal rat cardiomyocytes.
Shota Suzuki, Kametani Yusuke, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Obana Masanori, Okada Yoshiaki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 96 2022
Publisher: Japanese Pharmacological Society
PAI-1 induction is a critical event for the onset of lipopolysaccharide-induced acute kidney injury.
Koki Tanaka, Obana Masanori, Sakai Hibiki, Kamuro Hiroyasu, Yamamoto Ayaha, Tanaka Syota, Okada Yoshiaki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 96 2022
Publisher: Japanese Pharmacological Society
ポドサイトの転写因子OASISは腎病態進展に寄与する
三宅 芳明, 尾花 理徳, 山本 彩葉, 田中 翔大, 前田 真貴子, 今泉 和則, 淺沼 克彦, 藤尾 慈
日本腎臓学会誌 Vol. 63 No. 4 p. 499-499 2021/06
Publisher: (一社)日本腎臓学会ポドサイトの転写因子OASISは腎病態進展に寄与する
三宅芳明, 尾花理徳, 山本彩葉, 田中翔大, 前田真貴子, 今泉和則, 淺沼克彦, 藤尾慈
日本腎臓学会誌(Web) Vol. 63 No. 4 2021
ポドサイトにおける転写因子OASISの発現上昇は,ネフローゼ様症状を引き起こし腎臓の恒常性破綻に繋がる
尾花理徳, 尾花理徳, 尾花理徳, 尾花理徳, 三宅芳明, 山本彩葉, 田中翔大, 前田真貴子, 岡田欣晃, 今泉和則, 淺沼克彦, 藤尾慈, 藤尾慈
日本循環薬理学会口演要旨集 Vol. 31st 2021
Maresin-1 induces hypertrophy through IGF-1 paracrine system in cultured cardiomyocytes
WAHYUNI Tri, 田中翔大, 小林亜里沙, 三宅芳明, 山本彩葉, BAHTIAR Anton, 松本浩太朗, 前田真貴子, 尾花理徳, 藤尾慈
日本薬理学雑誌 Vol. 156 No. Supplement 2021
ポドサイトにおける転写因子Old Astrocyte Specifically Induced Substance（OASIS）の欠損は、Protein Kinase C Iotaを介してLPSによる尿細管傷害を抑制する
尾花理徳, 三宅芳明, 山本彩葉, 田中翔大, 前田真貴子, 今泉和則, 淺沼克彦, 藤尾慈
第30回日本循環薬理学会 2020/11 Research paper, summary (national, other academic conference)
β2-adrenergic signaling promotes IL-6 production from cardiac fibroblasts through CREB/Arid5a pathway and induces cardiac hypertorphy via paracrine system
Shota Tanaka, Atsuki Imaeda, Makiko Maeda, Masanori Obana, Yasushi Fujio
American Heart Association Scientific Sessions 2020 2020/11 Research paper, summary (international conference)
Maresin-1 Induces Cardiomyocyte Hypertrophy through RORα/IGFR1/PI3K/AKT pathway
Tri Wahyuni, Arisa Kobayashi, Shota Tanaka, Yoshiaki Miyake, Ayaha Yamamoto, Anton Bahtiar, Kotaro Matsumoto, Makiko Maeda, Masanori Obana, Yasushi Fujio
American Heart Association Scientific Sessions 2020 2020/11 Research paper, summary (international conference)
OASIS in podocytes promoted tubular injury by suppressing PRKCI expression
Yoshiaki Miyake, Masanori Obana, Ayaha Yamamoto, Takeo Harada, Takafumi Nakae, Shunsuke Noda, Sayuri Mitsuoka, Koki Tanaka, Shota Tanaka, Makiko Maeda, Kazunori Imaizumi, Katsuhiko Asanuma, Yasushi Fujio
ASN Kidney Week 2020 Annual Meeting 2020/10 Research paper, summary (international conference)
Cell death-induced myocardial inflammation and repair: Toward a novel therapy against heart failure
藤尾慈, 宮脇昭光, 尾花理徳, 松本浩太朗, 前田真貴子
日本薬学会年会要旨集(Web) Vol. 140th 2020
Suppression of transcription factor OASIS ameliorated kidney fibrosis.
Masanori Obana, Ayaha Yamamoto, Takafumi Nakae, Yoshiaki Miyake, Takeo Harada, Sayuri Mitsuoka, Shunsuke Noda, Makiko Maeda, Kazunori Imaizumi, Kotaro Matsumoto, Yasushi Fujio
ASN Kidney Week 2019 Annual Meeting 2019/11 Research paper, summary (international conference)
転写因子Old Astrocyte Specifically Induced Substance（OASIS）は新規腎線維化制御因子である.
尾花理徳, 山本彩葉, 中江崇文, 三宅芳明, 原田雄生, 光岡小百合, 前田真貴子, 今泉和則, 松本浩太朗, 藤尾慈
第29回日本循環薬理学会第55回高血圧関連疾患モデル学会合同学会 2019/11 Research paper, summary (national, other academic conference)
Runx2-expressing myeloid cells ameliorate post-infarct cardiac remodeling as a novel cardioprotective subset
Matsumoto Kotaro, Ashizuka Moe, Kumagai Shohei, Okuzaki Daisuke, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
Proceedings for Annual Meeting of The Japanese Pharmacological Society Vol. 92 p. 2-YIA-10 2019
Publisher: Japanese Pharmacological Society
Blockade of NKG2D / NKG2D Ligand Interaction Attenuated Post-Infarct Myocardial Injury.
Kotaro Matsumoto, Masanori Obana, Arisa Kobayashi, Miho Kihara, Go Shioi, Shigeru Miyagawa, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yoshiki Sawa, Yasushi Fujio
CIRCULATION Vol. 138 2018/11 Research paper, summary (international conference)
転写因子を標的とした慢性腎臓病治療法の開発を目指して.
尾花 理徳
第 11 回北陸合同バイオシンポジウム 2018/10 Research paper, summary (national, other academic conference)
転写因子OASISは筋線維芽細胞の増殖,遊走を介して腎線維化に関与する
尾花理徳, 守沖瞳, 山本彩葉, 金本聡自, 前田真貴子, 今泉和則, 中山博之, 藤尾慈
日本腎臓学会誌 Vol. 60 No. 3 p. 434-434 2018/04/30
Publisher: (一社)日本腎臓学会
慢性腎臓病に対する診断バイオマーカーの確立に向けた腎分泌蛋白質の有用性評価
石田 菜南, 東阪 和馬, 竹谷 苑子, 井阪 亮, 尾花 理徳, 鎌田 春彦, 前田 真貴子, 長野 一也, 藤尾 慈, 神出 計, 堤 康央
日本薬学会年会要旨集 Vol. 138年会 No. 4 p. 188-188 2018/03
Publisher: (公社)日本薬学会心分泌蛋白質に着目した心不全に対する新規バイオマーカー探索
東阪和馬, 東阪和馬, 大須賀絵理, 笠原淳平, 豊田麻人, 尾花理徳, 鎌田春彦, 前田真貴子, 長野一也, 藤尾慈, 藤尾慈, 藤尾慈, 坂田泰史, 坂田泰史, 堤康央, 堤康央
日本薬学会年会要旨集(CD-ROM) Vol. 138th No. 4 p. ROMBUNNO.27G‐pm06-61 2018/03
Publisher: (公社)日本薬学会
慢性腎臓病に対する診断バイオマーカーの確立に向けた腎分泌蛋白質の有用性評価
石田菜南, 東阪和馬, 東阪和馬, 竹谷苑子, 井阪亮, 尾花理徳, 鎌田春彦, 前田真貴子, 長野一也, 藤尾慈, 藤尾慈, 藤尾慈, 神出計, 神出計, 堤康央, 堤康央
日本薬学会年会要旨集(CD-ROM) Vol. 138th No. 4 p. ROMBUNNO.28PA‐pm318-188 2018/03
Publisher: (公社)日本薬学会
Podocyteにおける転写因子OASISは糖尿病性腎症進展に寄与する
三宅芳明, 尾花理徳, 山本彩葉, 中江崇文, 原田雄生, 金本聡自, 前田真貴子, 淺沼克彦, 今泉和則, 中山博之, 藤尾慈, 藤尾慈
日本薬理学会近畿部会プログラム・要旨集 Vol. 133rd 2018
Myofibroblast-Specific Deletion of Runx2 Improves Systolic Function and Survival in Late Phase of Cardiac Remodeling After Myocardial Infarction
Tanaka Shota, Enomoto Daichi, Yanase Emiko, Kumagai Shohei, Obana Masanori, Maeda Makiko, Fujio Yasushi, Nakayama Hiroyuki
CIRCULATION Vol. 136 2017/11/14
ROR gamma t heterozygous deficiency aggravates cardiac remodeling after myocardial infarction
Enomoto Daichi, Obana Masanori, Matsumoto Kotaro, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 133 No. 3 2017/03
Fibroblast-specific PKA activation induces cardiac hypertrophy
Takahashi Misato, Tonegawa Kota, Fuchigami Shota, Tanaka Shota, Obana Masanori, Maeda Makiko, Fujio Yasushi, Nakayama Hiroyuki
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 133 No. 3 2017/03
Elucidation of underlying mechanism of dynasore against ROS-induced CM death
Kawakatsu Ikki, Morihara Hirofumi, Kimura Rumi, Kubo Mikiko, Tsuchiyama Daisuke, Obana Masanori, Maeda Makiko, Fujio Yasushi, Nakayama Hiroyuki
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 133 No. 3 2017/03
The deletion of Runx2 in fibroblasts has a protective role after MI
Yanase Emiko, Tanaka Shouta, Kumagai Shouhei, Enomoto Daichi, Nakayama Nami, Obana Masanori, Maeda Makiko, Fujio Yasushi, Nakayama Hiroyuki
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 133 No. 3 2017/03
Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates tissue restoration with protrusion formation
Mitsuhara Yusuke, Miyawaki Akimitsu, Orimoto Aya, Nakayasu Yusuke, Tsunoda Shin-ichi, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Yoshioka Yasuo, Tsutsumi Yasuo, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 133 No. 3 2017/03
eIF4B is a cytoprotective molecule downstream of Pim-1 kinase in cardiomyocytes
Yokoyama Yukari, Matsumoto Kotaro, Kinoshita Maki, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 133 No. 3 2017/03
慢性腎臓病の早期診断に向けた新規バイオマーカーの探索
竹谷 苑子, 東阪 和馬, 井阪 亮, 石田 菜南, 鎌田 春彦, 尾花 理徳, 前田 真貴子, 長野 一也, 楽木 宏実, 藤尾 慈, 神出 計, 堤 康央
日本薬学会年会要旨集 Vol. 137年会 No. 4 p. 112-112 2017/03
Publisher: (公社)日本薬学会腎線維化病態における転写因子OASISの役割
守沖瞳, 尾花理徳, 山本彩葉, 金本聡自, 前田真貴子, 今泉和則, 中山博之, 藤尾慈, 藤尾慈
日本薬理学会近畿部会プログラム・要旨集 Vol. 132nd 2017
心筋細胞におけるR‐spondin1の形態学的機能
関谷有紀子, 尾花理徳, 宮脇昭光, 松本浩太郎, 榎本大智, 前田真貴子, 中山博之, 藤尾慈, 藤尾慈
日本薬理学会近畿部会プログラム・要旨集 Vol. 132nd 2017
細胞死抑制因子Dad1の心筋細胞における意義
木村瑠美, 松本浩太朗, 森原啓文, 尾花理徳, 前田真貴子, 藤尾慈, 藤尾慈, 中山博之
日本薬理学会近畿部会プログラム・要旨集 Vol. 132nd 2017
心筋炎回復過程における心筋細胞の内因性増殖機構の解析
折本彩, 中安佑介, 松井理紗, 宮脇昭光, 尾花理徳, 前田真貴子, 中山博之, 藤尾慈, 藤尾慈
日本薬理学会近畿部会プログラム・要旨集 Vol. 132nd 2017
Myeloid Cell-Specific Runx2 Deficiency Exacerbates Adverse Cardiac Remodeling After Myocardial Infarction
Moe Ashizuka, Shouhei Kumagai, Emiko Yanase, Masanori Obana, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 134 2016/11 Research paper, summary (international conference)
Heterozygous Ablation of ROR gamma t Gene Deteriorates Adverse Cardiac Remodeling After Myocardial Infarction
Daichi Enomoto, Masanori Obana, Kotaro Matsumoto, Yasushi Sakata, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 134 2016/11 Research paper, summary (international conference)
Adult Mammalian Hearts Restore Intrinsic Regenerative Capacity Through Signal Transducer and Activation of Transcription 3 in the Resolution Phase of Myocarditis
Akimitsu Miyawaki, Masanori Obana, Yusuke Mitsuhara, Aya Orimoto, Yusuke Nakayasu, Tomomi Yamashita, So-ichiro Fukada, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 134 2016/11 Research paper, summary (international conference)
Myeloid Cell-Specific Runx2 Deficiency Exacerbates Adverse Cardiac Remodeling After Myocardial Infarction
Moe Ashizuka, Shouhei Kumagai, Emiko Yanase, Masanori Obana, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 134 2016/11 Research paper, summary (international conference)
Heterozygous Ablation of ROR gamma t Gene Deteriorates Adverse Cardiac Remodeling After Myocardial Infarction
Daichi Enomoto, Masanori Obana, Kotaro Matsumoto, Yasushi Sakata, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 134 2016/11 Research paper, summary (international conference)
Fibroblast-specific Beta-adrenergic Receptor Signaling Regulates Cardiac Hypertrophy in Mice
Kota Tonegawa, Shota Tanaka, Misato Takahashi, Shota Fuchigami, Masanori Obana, Makiko Maeda, Yasushi Sakata, Yasushi Fujio, Hiroyuki Nakayama
CIRCULATION Vol. 134 2016/11 Research paper, summary (international conference)
Adult Mammalian Hearts Restore Intrinsic Regenerative Capacity Through Signal Transducer and Activation of Transcription 3 in the Resolution Phase of Myocarditis
Akimitsu Miyawaki, Masanori Obana, Yusuke Mitsuhara, Aya Orimoto, Yusuke Nakayasu, Tomomi Yamashita, So-ichiro Fukada, Makiko Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 134 2016/11 Research paper, summary (international conference)
心筋炎病態においてSca‐1陽性心筋組織幹細胞は心保護的性質へと変化する
榎原正貴, 松原由実, 宮脇昭光, 関谷有紀子, 尾花理徳, 前田真貴子, 中山博之, 藤尾慈
日本薬学会年会要旨集(CD-ROM) Vol. 136th No. 3 p. ROMBUNNO.27O‐AM03-63 2016/03
Publisher: (公社)日本薬学会
Pim‐1を介したSTAT3による新規細胞保護機構の解明
大谷勇太, 横山由加里, 尾花理徳, 前田真貴子, 中山博之, 藤尾慈
日本薬学会年会要旨集(CD-ROM) Vol. 136th No. 3 p. ROMBUNNO.27O‐AM04-63 2016/03
Publisher: (公社)日本薬学会
心筋炎病態下におけるSTAT3を介した成体心筋細胞増殖
高家圭紀, 宮脇昭光, 密原佑介, 尾花理徳, 前田真貴子, 中山博之, 藤尾慈
日本薬学会年会要旨集(CD-ROM) Vol. 136th No. 3 p. ROMBUNNO.27O‐AM05-63 2016/03
Publisher: (公社)日本薬学会
活性酸素種を標的とした2‐Aminoethyl diphenyl borinateの心虚血再灌流に対する傷害抑制効果
森原啓文, 尾花理徳, 川勝一輝, 土山大介, 石田瑛子, 前田真貴子, 藤尾慈, 中山博之
日本薬学会年会要旨集(CD-ROM) Vol. 136th No. 3 p. ROMBUNNO.27O‐AM06S-64 2016/03
Publisher: (公社)日本薬学会
Adult cardiomyocytes restore intrinsic regenerative capacity through STAT3 activation in the inflamed murine heart
Miyawaki Akimitsu, Takaya Tamaki, Mitsuhara Yusuke, Yamashita Tomomi, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 130 No. 3 2016/03
Elucidation of underlying mechanism of 2-APB against ROS-induced CM death
Ishida Akiko, Morihara Hirofumi, Kawakatsu Ikki, Tsuchiyama Daisuke, Kubo Mikiko, Obana Masanori, Maeda Makiko, Fujio Yasushi, Nakayama Hiroyuki
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 130 No. 3 2016/03
Myeloid Cell Derived Leucine Rich alpha 2 Glycoprotein Attenuates Adverse Cardiac Remodeling After Myocardial Infarction
Shohei Kumagai, Hiroyuki Nakayama, Minoru Fujimoto, Hiromi Honda, Satoshi Serada, Atsushi Kasai, Masanori Obana, Yasushi Sakata, Yoshiki Sawa, Tetsuji Naka, Yasushi Fujio
CIRCULATION Vol. 132 2015/11 Research paper, summary (international conference)
Cardiac STAT3 Activation in Subacute Phase of Myocardial Infarction was Required for the Suppression of Adverse Cardiac Remodeling
Daichi Enomoto, Masanori Obana, Akimitsu Miyawaki, Tomomi Mohri, Makio Maeda, Yasushi Sakata, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 132 2015/11 Research paper, summary (international conference)
Adrenergic Receptors beta 2 and beta 3 Transduce Differential Signals in Cardiac Fibroblasts
Kota Tonegawa, Hiroyuki Nakayama, Hiromi Igarashi, Sachi Matsunami, Nao Hayamizu, Masanori Obana, Makiko Maeda, Yasushi Fujio
CIRCULATION Vol. 132 2015/11 Research paper, summary (international conference)
Elucidation of molecular mechanism of cardiomyocyte necrosis induced by reactive oxygen species
Tsuchiyama Daisuke, Nakayama Hiroyuki, Morihara Hirofumi, Ishida Akiko, Obana Masanori, Maeda Makiko, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 128 No. 3 2015/07
Interleukin 27 induces endothelial differentiation in murine cardiac stem cells
Tanaka Tomohiro, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 128 No. 3 2015/07
IL-27 negatively regulates murine experimental autoimmune myocarditis (EAM)
Furutani Chika, Miyawaki Akimitsu, Otani Yuta, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 128 No. 3 2015/07
The properties of cardiac Sca-1+resident stem cells are altered in response to myocardial inflammation
Matsuhara Yumi, Miyawaki Akimitsu, Ebara Masaki, Obana Masanori, Maeda Makiko, Nakayama Hiroyuki, Fujio Yasushi
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 128 No. 3 2015/07
炎症関連タンパク質Leucine Rich α2 Glycoprotein(LRG)は,心筋梗塞後リモデリングを抑制する
中山博之, 熊谷渉平, 藤本穣, 本田宏美, 世良田聡, 笠井淳司, 尾花理徳, 仲哲治, 藤尾慈
日本薬理学会西南部会プログラム/抄録集 Vol. 68th 2015
骨髄由来のLeucine Rich α2 Glycoprotein(LRG)は,心筋梗塞後リモデリングを抑制する
中山博之, 熊谷渉平, 尾花理徳, 藤本穣, 本田宏美, 世良田聡, 笠井淳司, 仲哲治, 藤尾慈
日本循環薬理学会口演要旨集 Vol. 25th 2015
心筋梗塞慢性期における心筋特異的STAT3の欠損は心筋リモデリングを悪化させる
榎本大智, 尾花理徳, 宮脇昭光, 毛利友美, 前田真貴子, 中山博之, 藤尾慈
生体機能と創薬シンポジウム要旨集 Vol. 2014 2014
The ablation of ROR gamma t gene results in advanced cardiac fibrosis after Myocardial Infarction
Tomomi Yamashita, Masanori Obana, Akiko Hayama, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 118 p. 76P-76P 2012 Research paper, summary (international conference)
Interleukin-11 Exhibits the Post-conditioning Effects against Ischemia Reperfusion injury via Cardiac Signal Transducer and Activator of Transcription 3
Kaori Miyamoto, Masanori Obana, Makiko Maeda, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 118 p. 86P-86P 2012 Research paper, summary (international conference)
Th17 Cells Exhibit Protective Effects Against Cardiac Fibrosis After Myocardial Infarction
Tomomi Yamashita, Masanori Obana, Akiko Hayama, Tomohiko Iwakura, Issei Komuro, Hiroyuki Nakayama, Yasushi Fujio
CIRCULATION Vol. 124 No. 21 2011/11 Research paper, summary (international conference)
Disruption of leptin signal exacerbates myocardial injury by enhancing ER stress after myocardial infarction
Momoko Shiragaki, Masanori Obana, Shiho Murasawa, Kaori Miyamoto, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 115 p. 111P-111P 2011 Research paper, summary (international conference)
PTP1B negatively regulates JAK/STAT cardioprotective signaling in cardiomyocytes
Shiho Murasawa, Masanori Obana, Tomohiko Iwakura, Kazuki Matsui, Momoko Shiragaki, Kohei Katayama, Kaori Miyamoto, Junichi Azuma, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 115 p. 89P-89P 2011 Research paper, summary (international conference)
Interleukin-11 exhibits the post-conditioning effects against ischemia reperfusion injury through cardiac STAT3 activation
Masanori Obana, Kaori Miyamoto, Tomohiko Iwakura, Akiko Hayama, Tomomi Yamashita, Shiho Murasawa, Momoko Shiragaki, Makiko Maeda, Junichi Azuma, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 115 p. 110P-110P 2011 Research paper, summary (international conference)
Interleukin-6 family cytokines induce endothelial cell differentiation of cardiac Sca-1+cells via STAT3/Pim-1 signaling pathway
Tomohiko Iwakura, Tomomi Mohri, Tatsuto Hamatani, Tomomi Yamashita, Masanori Obana, Akiko Hayama, Kazuki Matsui, Makiko Maeda, Junichi Azuma, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 115 p. 96P-96P 2011 Research paper, summary (international conference)
Cathelicidin antimicrobial peptide (CAMP) is induced in autoimmune myocarditis and reduces the motility of cardiac fibroblasts
Kazuki Matsui, Tomomi Yamashita, Haruyo Kawaguchi, Tomohiko Iwakura, Masanori Obana, Akiko Hayama, Shiho Murasawa, Kohei Katayama, Momoko Shiragaki, Makiko Maeda, Junichi Azuma, Hiroyuki Nakayama, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 115 p. 110P-110P 2011 Research paper, summary (international conference)
Pim-1 Kinase is Required for Endothelial Differentiation of Cardiac Stem Cells via STAT3 Signaling Pathway
Tomohiko Iwakura, Tomomi Mohri, Tatsuto Hamatani, Tomomi Yamashita, Masanori Obana, Akiko Hayama, Makiko Maeda, Hiroyuki Nakayama, Issei Komuro, Junichi Azuma, Yasushi Fujio
CIRCULATION Vol. 122 No. 21 2010/11 Research paper, summary (international conference)
心臓血管の発生,疾患に関与する新しい注目すべき分子 IL‐11の心血管系における作用
尾花理徳, 前田真貴子, 藤尾慈
循環器内科 Vol. 67 No. 2 p. 156-162 2010/02/28
Publisher: (有)科学評論社
Interleukin-11 ameliorates cardiac remodeling after myocardial infarction through STAT3
Masanori Obana, Makiko Maeda, Junichi Azuma, Yasushi Fujio
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 112 p. 74P-74P 2010 Research paper, summary (international conference)
虚血再灌流傷害におけるIL‐11のpost‐conditioning効果について
宮本香織, 尾花理徳, 前田真貴子, 東純一, 中山博之, 藤尾慈
日本薬理学会近畿部会プログラム・要旨集 Vol. 118th 2010
Analyses on the in vivo transdifferentiation of cardiac stem cells into endothelial cell lineage in post-infarct myocardium
Koichi Matsuda, Yasushi Fujio, Tomomi Mohri, Masanori Obana, Tomohiko Iwakura, Tomomi Yamashita, Akiko Hayama, Makiko Maeda, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 109 p. 118P-118P 2009 Research paper, summary (international conference)
Th17 cells are induced in chronic inflammation after myocardial infarction
Akiko Hayama, Yasushi Fujio, Masanori Obana, Tomomi Mohri, Tomomi Yamashita, Tomohiko Iwakura, Makiko Maeda, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 109 p. 118P-118P 2009 Research paper, summary (international conference)
IL-6 family cytokines induce IL-10 in cardiac myocytes via STAT3 and ERK1/2 signaling pathway
Tomohiko Iwakura, Yasushi Fujio, Makiko Maeda, Tomomi Mohri, Masanori Obana, Koichi Matsuda, Tomomi Yamashita, Akiko Hayama, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 109 p. 62P-62P 2009 Research paper, summary (international conference)
The infiltration of Th17 cells into myocardium is associated with severity of the inflammation in experimental autoimmune myocarditis (EAM)
Tomomi Yamashita, Yasushi Fujio, Akiko Hayama, Kouichi Matsuda, Masanori Obana, Tomohiko Iwakura, Tornomi Mohri, Makiko Maeda, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 109 p. 117P-117P 2009 Research paper, summary (international conference)
Signals through gp130 mediate the endothelial differentiation in cardiac Sca-1+stem cells
Tomomi Mohri, Yasushi Fujio, Tomohiko Iwakura, Masanori Obana, Koichi Matsuda, Makiko Maeda, Takashi Ito, Yasuhiro Yamamoto, Nozomi Hayata, Akiko Hayama, Tomomi Yamashita, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 106 p. 58P-58P 2008 Research paper, summary (international conference)
Skeletal muscle-derived Sca-1+stem cells are differentiated into endothelial cells by Leukemia inhibitory factor
Tomohiko Iwakura, Yasushi Fujio, Makiko Maeda, Tomomi Mohri, Koichi Matsuda, Tomomi Yamashita, Takashi Ito, Yasuhiro Yamamoto, Masanori Obana, Nozomi Hayata, Mika Takai, Akiko Hayama, Yukako Ueno, Haruaki Nobori, Kouhei Yamashita, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 106 p. 99P-99P 2008 Research paper, summary (international conference)
Interleukin (IL)-11 ameliorates cardiac remodeling with angiogenic and anti-inflammatory effects in murine myocardial infarction model
Masanori Obana, Makiko Maeda, Yasubito Yamamoto, Takashi Ito, Tomomi Mohri, Tomohiko Iwakura, Nozomi Hayata, Mika Takai, Akiko Hayama, Koichi Matsuda, Kouhei Yamashita, Yasushi Fujio, Juriichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 106 p. 112P-112P 2008 Research paper, summary (international conference)
Connective tissue growth factor mediates hypertrophic signals through its C-terminal domain in cultured cardiac myocytes
Nozomi Hayata, Yasushi Fujio, Takashi Ito, Tomomi Mohri, Yasuhiro Yamamoto, Masanori Obana, Tomohiko Iwakura, Mika Takai, Koichi Matsuda, Yukako Ueno, Makiko Maeda, Shinpei Nonen, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 106 p. 120P-120P 2008 Research paper, summary (international conference)
血小板減少症治療薬インターロイキン(IL)‐11を用いた心不全に対するサイトカイン療法II―慢性モデルを用いた検討―
藤尾慈, 尾花理徳, 有田惇之, 山本泰弘, 毛利朋美, 岩倉智彦, 早田望, 端山明子, 松田浩一, 前田真貴子, 東純一
臨床薬理 Vol. 38 No. Supplement p. S206-S206 2007/11/15
Publisher: (一社)日本臨床薬理学会
血小板減少症治療薬インターロイキン(IL)‐11を用いた心不全に対するサイトカイン療法I―急性モデルを用いた検討―
前田真貴子, 有田惇之, 尾花理徳, 山本泰弘, 毛利朋美, 岩倉智彦, 早田望, 端山明子, 松田浩一, 藤尾慈, 東純一
臨床薬理 Vol. 38 No. Supplement p. S205-S205 2007/11/15
Publisher: (一社)日本臨床薬理学会
Interleukin-11 prevents cardiac remodeling after myocardial infarction with Neovascularization in murine model
Masanori Obana, Makiko Maeda, Yasuhiro Yamamoto, Takashi Ito, Tomomi Mohn, Tomohiko Iwakura, Nozomi Hayata, Mika Takai, Akiko Hayama, Koichi Matsuda, Kouhei Yamashita, Yasushi Fujio, Junichi Azuma
CIRCULATION Vol. 116 No. 16 p. 262-262 2007/10 Research paper, summary (international conference)
Signals through glycoprotein 130 promote the endothelial differentiation of cardiac Sca(-1)+ cells
Tomomi Mohri, Yasushi Fujio, Tomohiko Iwakura, Masanori Obana, Koichi Matsuda, Makiko Maeda, Takashi Ito, Yasuhiro Yamamoto, Nozomi Hayata, Junichi Azuma
CIRCULATION Vol. 116 No. 16 p. 48-48 2007/10 Research paper, summary (international conference)
血小板減少症治療薬インターロイキン11(IL‐11)の心不全発症予防薬としての可能性と研究意義
前田真貴子, 有田敦之, 尾花理徳, 山本泰弘, 毛利友美, 岩倉智彦, 松田浩一, 端山明子, 山下朋美, 藤尾慈, 東純一
医療薬学フォーラム講演要旨集 Vol. 15th 2007/07
Interleukin (IL)-11 prevents ischemia/reperfusion (I/R) injury in hearts as a novel card ioprotective cytokine.
Makiko Maeda, Ryusuke Kimura, Atsushi Arita, Masanori Obana, Yasuhiro Yamamoto, Tomomi Mohri, Tomohiko Iwakura, Koichi Mastuda, Takashi Ito, Yasushi Kimura, Yuichi Oshima, Yasushi Fujio, Junichi Azuma
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 103 p. 117P-117P 2007 Research paper, summary (international conference)
Atrogin-1 ubiquitin ligase is upregulated by doxorubicin, leading to muscle atrophy in cardiac myocytes
Yasushi Fujio, Yuki Hoshino-Nariai, Yasuhiro Yamamoto, Takashi Ito, Yoriko Uozumi, Tomomi Mohri, Masanori Obana, Tetsurou Nariai, Yasushi Kimura, Makiko Maeda, Junichi Azuma
CIRCULATION Vol. 114 No. 18 p. 332-332 2006/10 Research paper, summary (international conference)
腎疾患病態形成における内在性レトロウイルスの役割
尾花理徳
ファルマシア 2023/10
ベーシック薬学教科書シリーズ19 薬物治療学（第2版)
平井みどり, 三木知博
化学同人 2019/04 Textbook, survey, introduction
ISBN: 9784759816297
循環器内科
尾花理徳, 前田真貴子, 藤尾慈
科学評論社 2010/02 Scholarly book
ミエロイド細胞に着目した心腎病態共通分子基盤の探索
尾花理徳, 坂井響, 冨松聖史, 藤尾慈
生体機能と創薬シンポジウム2024京都 2024/08/29
JAK inhibition in the early phase of SARS-CoV-2 infection exacerbates kidney injury along with decreased endogenous antiviral activity in mice
Masanori Obana, Hibiki Sakai, Hiroyasu Kamuro, Nagisa Tokunoh, Ayaha Yamamoto, Yoshiaki Okada, Yasuo Yoshioka, Yasushi Fujio
第67回日本腎臓学会学術総会 2024/06/29
慢性腎臓病治療薬開発に資する、新規腎病態制御分子の探索
尾花理徳
第33回日本循環薬理学会 2024/01/27
Exploration of novel regulators of kidney fibrosis
2023/12/16
Unveiling novel podocyte-expressed molecules in kidney disease progression
2023/12/16
新規無針デバイスを用いた遺伝子導入による、心疾患治療法開発のための取り組み
尾花理徳
第44回日本臨床薬理学会学術総会 ランチョンセミナー 2023/12/14
腎疾患治療法開発を目指した新たな病態制御分子の役割解明
尾花理徳
生体機能と創薬シンポジウム2023 2023/08/25
ポドサイトの転写因子OASIS―腎炎をはじめとした腎疾患の新たな分子病態の解明へー
尾花理徳
第66回日本腎臓学会学術総会 2023/06/10
心筋梗塞で動員される新規ミエロイド細胞サブセットが慢性腎臓病病態形成に与える影響
尾花理徳
第70回日本心臓病学会学術集会 公益財団法人循環器病研究振興財団 バイエル循環器病研究助成研究発表会 2022/09/25
構造分子薬理学的研究から解き明かす新たな炎症制御機構
尾花理徳, 福田庸太
先導的学際研究機構 生命医科学融合フロンティア研究部門 第4回研究報告会 2022/09/22
ポドサイトにおける転写因子OASISの発現上昇は、ネフローゼ様症状を引き起こし腎臓の恒常性破綻に繋がる
尾花理徳, 三宅芳明, 山本彩葉, 田中翔大, 前田真貴子, 岡田欣晃, 今泉和則, 淺沼克彦, 藤尾慈
第31回日本循環薬理学会 2021/12/03
ポドサイトにおける転写因子Old Astrocyte Specifically Induced Substance（OASIS）の欠損は、Protein Kinase C Iotaを介してLPSによる尿細管傷害を抑制する
尾花理徳
第30回循環薬理学会 2020/11/27
転写因子Old Astrocyte Specifically Induced Substance（OASIS）は新規腎線維化制御因子である.
尾花理徳
第29回日本循環薬理学会第55回高血圧関連疾患モデル学会合同学会 2019/11
Suppression of transcription factor OASIS ameliorated kidney fibrosis.
Masanori Obana
ASN Kidney Week 2019 Annual Meeting 2019/11
転写因子を標的とした慢性腎臓病治療法の開発を目指して.
尾花理徳
第 11 回北陸合同バイオシンポジウム 2018/10
転写因子OASISは筋線維芽細胞の増殖,遊走を介して腎線維化に関与する
尾花理徳
日本腎臓学会学術集会 2018/06
インターロイキン１１の心疾患治療薬としての利用
東純一, 藤尾慈, 木村竜介, 前田真貴子, 有田惇之, 尾花理徳, 伊藤崇志, 福田剛史
特許第5191393号
出願日:2007/10/24
登録日:2013/02/08
血管内皮バリア破綻の阻害剤、呼吸器感染症治療用医薬組成物及び血管内皮バリア破綻の阻害剤のスクリーニング方法
高山和雄, 橋本里奈, 岡田欣晃, 藤尾慈, 尾花理徳, 高橋潤也, 吉岡靖雄
出願日:2022/04/08
Use of interleukin-11 as therapeutic agent for heart disease
東純一, 藤尾慈, 木村竜介, 前田真貴子, 有田惇之, 尾花理徳, 伊藤崇志, 福田剛史
特許8,361,966
Metabolite phosphatase from anhydrobiotic tardigrades
Kato Subaru, Deguchi Koki, Obana Masanori, Fujio Yasushi, Fukuda Yohta, Inoue Tsuyoshi
FEBS Journal Vol. 291 No. 23 p. 5195-5213 2024/10/17
Endothelial ROBO4 suppresses PTGS2/COX-2 expression and inflammatory diseases
Tanaka Masato, Shirakura Keisuke, Takayama Yui, Μatsui Miki, Watanabe Yukio, Yamamoto Takuya, Takahashi Junya, Tanaka Shota, Hino Nobumasa, Doi Takefumi, Obana Masanori, Fujio Yasushi, Takayama Kazuo, Okada Yoshiaki
Communications Biology Vol. 7 2024/05/18
