顔写真

PHOTO

Takao Toshifumi
高尾　敏文
Takao Toshifumi
高尾　敏文
Institute for Protein Research, Specially Appointed Professor

Research History 5

  1. 2024/05 - Present
    Osaka University　Institute for Protein Research　Specially Appointed Professor

  2. 1987 - 1996
    Osaka University　Institute for Protein Research

  3. 1987 - 1996
    Osaka University, Institute for Protein Research, Instructor

  4. 1996 -
    - 大阪大学蛋白質研究所 助教授

  5. 1996 -
    - Osaka University, Institute for Protein Research, Associate Professor

Education 4

  1. Osaka University

    - 1986

  2. Osaka University　Graduate School, Division of Natural Science

    - 1986

  3. Osaka University　School of Science

    - 1981

  4. Osaka University　Faculty of Science

    - 1981

Professional Memberships 5

  1. 日本質量分析学会

  2. 日本ペプチド学会

  3. アメリカ質量分析学会(The American Society for Mass Spectrometry)

  4. 日本生化学会

  5. 日本化学会

Research Areas 1

  1. Life sciences / Structural biochemistry /

Awards 3

  1. Dr. Honoris Causa

    from the University of Havana　2022/11

  2. 日本生化学会奨励賞

    1994

  3. 内藤記念科学奨励金

    1992

Papers 121

  1. Characteristic fragmentation of polyunsaturated fatty acids with allylic vicinal diols in positive-ion LC/ESI-MS/MS.

    Huibin Zhu, Mone Kurokawa, Mengyao Chen, Qiuyi Wang, Masayuki Inoue, Toshifumi Takao

    Journal of lipid research　Vol. 64　No. 6　p. 100384-100384　2023/06　Research paper (scientific journal)

  2. Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K carrier protein from Neisseria meningitidis

    Luis Javier González, Pedro E. Encinosa Guzmán, Wendy Machado, Satomy Pousa, Alejandro Leyva, Ana Laura Cano Arguelles, Gleysin Cabrera, Luis Ariel Espinosa, Rubén Parra, Rachel Hernández, Yamil Bello Soto, Frank L. Ledesma, Marisdania Joglar, Osmany Guirola, Louise Ulrich Kurt, Paulo C. Carvalho, Ania Cabrales, Hilda Garay, Vladimir Besada, Rosario Durán, Toshifumi Takao, Mario Pablo Estrada, Alina Rodríguez-Mallon

    Analytical and Bioanalytical Chemistry　Vol. 413　No. 23　p. 5885-5900　2021/09　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  3. Biological age prediction using a DNN model based on pathways of steroidogenesis

    Qiuyi Wang, Zi Wang, Kenji Mizuguchi, Toshifumi Takao

    Science Advances　Vol. 11　No. 11　2025/03/14　Research paper (scientific journal)

    Publisher: American Association for the Advancement of Science (AAAS)

  4. Resolvin D4 mitigates lipopolysaccharide-induced lung injury in mice

    Rika Inomata, Hironobu Tsubouchi, Toshifumi Takao, Mone Kurokawa, Shigehisa Yanagi, Katsuya Sakai, Taiga Miyazaki

    Prostaglandins, Leukotrienes and Essential Fatty Acids　Vol. Volume 203,　2024/10/04

  5. On the utility of the extracted ion chromatograms for assigning the conjugation sites and side reactions in bioconjugates synthesized by the maleimide-thiol chemistry

    Satomy Pousa a, Pablo E. Ramos-Bermúdez b, Vladimir Besada a, Paulo Carvalho c, Louise Kur, Ulrich c, Michel Batista c, Rodrigo Soares Caldeira Brant c, Olivia Martínez d, Alejandro Leyva e, Rosario Durán e f, Dhayme Murillo g, Abel Fajardo g, Hilda Elisa Garay g, Alina Rodríguez-Mallón h, Toshifumi Takao i, Luis Javier González a

    Microchemical Journal　2024/09

  6. A hydrolyzed N-propionylthiosuccinimide linker is cleaved by metastable fragmentation, increasing reliability of conjugation site identification in conjugate vaccines

    Pablo E. Ramos-Bermúdez, Satomy Pousa, Paulo Carvalho, Rodrigo Soares, Caldeira Bran, Michel Batista, Hironobu Hojo, Hilda E. Garay, Abel Roscoe, Alina Rodríguez Mallón, Vladimir Besada, Toshifumi Takao, Luis Javier González

    Rapid Communications in Mass Spectrometry:　2024/07/21

  7. Identification of a urinary CD276 fragment for detecting resectable pancreatic cancer using a C-terminal proteomics strategy

    Shuichi Mitsunaga, Nobuaki Okumura, Toshiki Takei, Toshifumi Takao, Hironobu Tsubouchi, Kohei Nakata, Masafumi Nakamura, Yuji Kitahata, Hideki Motobayashi, Masafumi Ikeda, Masamitsu Nakazato

    Scientific Reports　Vol. 14　No. 1　2024/06/20　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  8. Profiling of urinary steroids aided by lithium ion adduction-based ultrahigh-performance liquid chromatography–tandem mass spectrometry

    Yue Pan, Qiuyi Wang, Mengyao Chen, Toshifumi Takao

    Rapid Communications in Mass Spectrometry　2024/03/18

  9. Differentiation of isobaric cross‐linked peptides prepared via maleimide chemistry using MALDI‐MS and MS/MS

    Luis Javier González, Satomy Pousa, Hironobu Hojo, Shio Watanabe, Daisuke Higo, Alina Rodriguez Mallon, Toshifumi Takao

    Rapid Communications in Mass Spectrometry　Vol. 38　No. 2　2023/11/22　Research paper (scientific journal)

    Publisher: Wiley

  10. Positive-Ion LC/ESI-MS/MSによるアリルビシナルジオールを含む多価不飽和脂肪酸の定量解析

    黒川 萌音, 坪内 拡伸, 朱 慧彬, 陳 蒙瑶, 井上 将行, 宮崎 泰可, 高尾 敏文

    日本生化学会大会プログラム・講演要旨集　Vol. 96回　p. [1P-086]　2023/10

    Publisher: (公社)日本生化学会

  11. LC-MS/MSを用いた脱髄特異的なニューロステロイド種の同定

    櫻井 航輝, リ・スヤオ, ワン・チウイ, ハン・エツ, 高尾 敏文, 疋田 貴俊

    日本生化学会大会プログラム・講演要旨集　Vol. 96回　p. [2P-569]　2023/10

    Publisher: (公社)日本生化学会

  12. LC-MS/MSによる多発性硬化症モデルマウスにおける脱髄・炎症関連ニューロステロイドの探索

    櫻井 航輝, Li Li, Pan Pan, Wang Qiuyi, 高尾 敏文, 疋田 貴俊

    日本神経精神薬理学会年会プログラム・抄録集　Vol. 53回　p. 153-153　2023/09

    Publisher: (一社)日本神経精神薬理学会

  13. Rapid Chemical Synthesis of Serine Protease Inhibitor Kazal-type 13 (SPINK13) Glycoform by a Combined Method with Glycan Insertion Strategy and Fast-Flow Fmoc SPPS.

    Kota Nomura, Ryo Okamoto, Yuta Maki, Ayumu Hayashibara, Toshifumi Takao, Tomoya Fukuoka, Eiji Miyoshi, Bradley L Pentelute, Yasuhiro Kajihara

    Chemistry (Weinheim an der Bergstrasse, Germany)　Vol. 29　No. 42　2023/07/26　Research paper (scientific journal)

  14. Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via IP3 receptors

    Takuma Kozono, Chifuyu Jogano, Wataru Okumura, Hiroyuki Sato, Hitomi Matsui, Tsubasa Takagi, Nobuaki Okumura, Toshifumi Takao, Takashi Tonozuka, Atsushi Nishikawa

    Journal of Cell Science　Vol. 136　No. 4　2023/02/15　Research paper (scientific journal)

    Publisher: The Company of Biologists

  15. Chemical synthesis of per-selenocysteine human epidermal growth factor.

    Toshiki Takei, Hideaki Tanaka, Nobuaki Okumura, Toshifumi Takao, Luis Moroder, Hironobu Hojo

    Journal of peptide science : an official publication of the European Peptide Society　2022/12/02　Research paper (scientific journal)

  16. Liver-expressed antimicrobial peptide 2 functions independently of growth hormone secretagogue receptor in calorie-restricted mice.

    Md Nurul Islam, Weidong Zhang, Katsuya Sakai, Yuki Nakazato, Ryota Tanida, Hideyuki Sakoda, Toshiki Takei, Toshifumi Takao, Masamitsu Nakazato

    Peptides　Vol. 151　p. 170763-170763　2022/05　Research paper (scientific journal)

    Publisher: Elsevier BV

  17. DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers.

    Mingyue Jin, Sakiko Matsumoto, Takashi Ayaki, Hodaka Yamakado, Tomoyuki Taguchi, Natsuko Togawa, Ayumu Konno, Hirokazu Hirai, Hiroshi Nakajima, Shoji Komai, Ryuichi Ishida, Syuhei Chiba, Ryosuke Takahashi, Toshifumi Takao, Shinji Hirotsune

    Nature communications　Vol. 13　No. 1　p. 6880-6880　2022　Research paper (scientific journal)

  18. Carnosine dipeptidase II (CNDP2) protects cells under cysteine insufficiency by hydrolyzing glutathione-related peptides

    Sho Kobayashi, Takujiro Homma, Nobuaki Okumura, Jia Han, Keita Nagaoka, Hideyo Sato, Hiroyuki Konno, Sohsuke Yamada, Toshifumi Takao, Junichi Fujii

    Free Radical Biology and Medicine　Vol. 174　p. 12-27　2021/07　Research paper (scientific journal)

  19. Total Synthesis and Structural Characterization of Caveolin‐1

    Hironobu Hojo, Toshiki Takei, Yuya Asahina, Nobuaki Okumura, Toshifumi Takao, Masatomo So, Isao Suetake, Takeshi Sato, Akihiro Kawamoto, Yoshio Hirabayashi

    Angewandte Chemie International Edition　Vol. 60　No. 25　p. 13900-13905　2021/06/14　Research paper (scientific journal)

    Publisher: Wiley

  20. Extracellular mRNA transported to the nucleus exerts translation-independent function.

    Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S

    Nat Commun.　Vol. 12　No. 1　2021/06　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  21. Analysis of ADAM12-Mediated Ephrin-A1 Cleavage and Its Biological Functions.

    Ieguchi K, Tomita T, Takao T, Omori T, Mishima T, Shimizu I, Tognolini M, Lodola A, Tsunoda T, Kobayashi S, Wada S, Maru Y

    International Journal of Molecular Sciences　Vol. 22　No. 5　2021/03　Research paper (scientific journal)

  22. Identification of the ternary complex of ribonuclease HI:RNA/DNA hybrid:metal ions by ESI mass spectrometry

    Tomoshige Ando, Nujarin Jongruja, Nobuaki Okumura, Kosuke Morikawa, Shigenori Kanaya, Toshifumi Takao

    Journal of Biological Chemistry　p. 100462-100462　2021/02　Research paper (scientific journal)

  23. Hippocampal 7α-Hydroxylated Neurosteroids Are Raised by Training and Bolster Remote Spatial Memory with Increase of the Spine Densities

    Maehata, K, Shimizu, K, Ikeno, T, Wang, Q, Sakurai, A, Wei, Z, Pan. Y, Takao. T, Fukada, Y

    iScience　Vol. 23　No. 10　p. 101559-101559　2020/10　Research paper (scientific journal)

    Publisher: Elsevier BV

  24. Metastable decomposition at the peptide C-terminus: Possible use in protein identification

    Yang Wang, Etsuko Nakajima, Yoshihito Okamura, Danqing Wang, Nobuaki Okumura, Toshifumi Takao

    Rapid Communications in Mass Spectrometry　Vol. 34　No. 9　2020/05　Research paper (scientific journal)

  25. Lithium ion adduction enables UPLC-MS/MS-based analysis of multi-class 3-hydroxyl group-containing keto-steroids.

    Qiuyi Wang, Kimiko Shimizu, Kanako Maehata, Yue Pan, Koki Sakurai, Takatoshi Hikida, Yoshitaka Fukada, Toshifumi Takao

    Journal of lipid research　Vol. 61　No. 4　p. 570-579　2020/04　Research paper (scientific journal)

  26. Chemical synthesis of ferredoxin with 4 selenocysteine residues using a segment condensation method

    Toshiki Takei, Tomoshige Ando, Toshifumi Takao, Yusuke Ohnishi, Genji Kurisu, Michio Iwaoka, Hironobu Hojo

    Chemical Communications　Vol. 56　No. 91　p. 14239-14242　2020　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)

  27. 新たな早期膵癌診断マーカーとしての尿中キニノーゲン(KNG)断片の可能性

    大野 泉, 光永 修一, 菅 元康, 池田 公史, 坪内 拡伸, 柳 重久, 奥村 宜明, 高尾 敏文, 中里 雅光

    膵臓　Vol. 34　No. 3　p. A260-A261　2019/06

    Publisher: (一社)日本膵臓学会

  28. The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis

    Itai N, Shimazu T, Kimura T, Ibe I, Yamashita R, Kaburagi Y, Dohi T, Tonozuka T, Takao T, Nishikawa A

    PLoS One (2018)　2018/11　Research paper (scientific journal)

  29. 尿中微量蛋白断片解析による新規肺腺癌診断マーカーの探索

    坪内 拡伸, 柳 重久, 松元 信弘, 三浦 綾子, 奥村 宣明, 高尾 敏文, 中里 雅光

    日本臨床分子医学会学術総会プログラム・抄録集　Vol. 55回　p. 50-50　2018/04

    Publisher: 日本臨床分子医学会

  30. The zinc form of carnosine dipeptidase 2 (CN2) has dipeptidase activity but its substrate specificity is different from that of the manganese form.

    Nobuaki Okumura, Toshifumi Takao

    Biochemical and biophysical research communications　Vol. 494　No. 3-4　p. 484-490　2017/12/16　Research paper (scientific journal)

  31. One-Pot Four-Segment Ligation Using Seleno- and Thioesters: Synthesis of Superoxide Dismutase

    Toshiki Takei, Tomoshige Andoh, Toshifumi Takao, Hironobu Hojo

    Angewandte Chemie - International Edition　Vol. 56　No. 49　p. 15708-15711　2017/12/04　Research paper (scientific journal)

    Publisher: Wiley-VCH Verlag

  32. Design of Tail-Clamp Peptide Nucleic Acid Tethered with Azobenzene Linker for Sequence-Specific Detection of Homopurine DNA

    Shinjiro Sawada, Toshifumi Takao, Nobuo Kato, Kunihiro Kaihatsu

    MOLECULES　Vol. 22　No. 11　2017/11　Research paper (scientific journal)

  33. Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice

    Sho Kobayashi, Jaeyong Lee, Toshifumi Takao, Junichi Fujii

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 491　No. 3　p. 649-655　2017/09　Research paper (scientific journal)

  34. Wnt5b-associated exosomes promote cancer cell migration and proliferation.

    Takeshi Harada, Hideki Yamamoto, Shosei Kishida, Michiko Kishida, Chihiro Awada, Toshifumi Takao, Akira Kikuchi

    Cancer science　Vol. 108　No. 1　p. 42-52　2017/01　Research paper (scientific journal)

  35. Involvement of Brain-Enriched guanylate Kinase-Associated protein (BEGAIN) in chronic pain after peripheral nerve injury

    Tayo Katano, Masafumi Fukuda, Hidemasa Furue, Maya Yamazaki, Manabu Abe, Masahiko Watanabe, Kazuhiko Nishida, Ikuko Yao, Akihiro Yamada, Yutaka Hata, Nobuaki Okumura, Takanobu Nakazawa, Tadashi Yamamoto, Kenji Sakimura, Toshifumi Takao, Seiji Ito

    eNeuro　Vol. 3　No. 5　2016/09/01　Research paper (scientific journal)

    Publisher: Society for Neuroscience

  36. Histone H4 lysine 20 acetylation is associated with gene repression in human cells

    Jun-Ya Kaimori, Kazumitsu Maehara, Yoko Hayashi-Takanaka, Akihito Harada, Masafumi Fukuda, Satoko Yamamoto, Naotsugu Ichimaru, Takashi Umehara, Shigeyuki Yokoyama, Ryo Matsuda, Tsuyoshi Ikura, Koji Nagao, Chikashi Obuse, Naohito Nozaki, Shiro Takahara, Toshifumi Takao, Yasuyuki Ohkawa, Hiroshi Kimura, Yoshitaka Isaka

    SCIENTIFIC REPORTS　Vol. 6　2016/04　Research paper (scientific journal)

  37. Evidence for an essential role of intradimer interaction in catalytic function of carnosine dipeptidase II using electrospray-ionization mass spectrometry.

    Nobuaki Okumura, Jun Tamura, Toshifumi Takao

    Protein science : a publication of the Protein Society　Vol. 25　No. 2　p. 511-22　2016/02　Research paper (scientific journal)

  38. Free Thiol of Transthyretin in Human Plasma Most Accessible to Modification/Oxidation

    Caroline Donzeli Pereira, Naoto Minamino, Toshifumi Takao

    ANALYTICAL CHEMISTRY　Vol. 87　No. 21　p. 10785-10791　2015/11　Research paper (scientific journal)

  39. Phospholipid methylation controls Atg32-mediated mitophagy and Atg8 recycling

    Kaori Sakakibara, Akinori Eiyama, Sho W. Suzuki, Machiko Sakoh-Nakatogawa, Nobuaki Okumura, Motohiro Tani, Ayako Hashimoto, Sachiyo Nagumo, Noriko Kondo-Okamoto, Chika Kondo-Kakuta, Eri Asai, Hiromi Kirisako, Hitoshi Nakatogawa, Osamu Kuge, Toshifumi Takao, Yoshinori Ohsumi, Koji Okamoto

    EMBO JOURNAL　Vol. 34　No. 21　p. 2703-2719　2015/11　Research paper (scientific journal)

  40. Chemical Synthesis of O-Glycosylated Human Interleukin-2 by the Reverse Polarity Protection Strategy

    Yuya Asahina, Shinobu Komiya, Ami Ohagi, Rina Fujimoto, Hiroko Tamagaki, Katsuhiro Nakagawa, Takashi Sato, Shizuo Akira, Toshifumi Takao, Akira Ishii, Yoshiaki Nakahara, Hironobu Hojo

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 54　No. 28　p. 8226-8230　2015/07　Research paper (scientific journal)

  41. Basolateral secretion of Wnt5a in polarized epithelial cells is required for apical lumen formation

    Hideki Yamamoto, Chihiro Awada, Shinji Matsumoto, Tomoyuki Kaneiwa, Takayuki Sugimoto, Toshifumi Takao, Akira Kikuchi

    JOURNAL OF CELL SCIENCE　Vol. 128　No. 5　p. 1051-1063　2015/03　Research paper (scientific journal)

  42. Greeting from the Chair of Journal Committee

    TAKAO Toshifumi

    J. Mass Spectrom. Soc. Jpn.　Vol. 63　No. 5　p. 104-104　2015

    Publisher: The Mass Spectrometry Society of Japan

  43. Purification, crystallization and preliminary X-ray analysis of an HA17-HA70 (HA2-HA3) complex from Clostridium botulinum type C progenitor toxin

    Chikako Iwasa, Takashi Tonozuka, Masaya Shinoda, Yoshimasa Sagane, Koichi Niwa, Toshihiro Watanabe, Hiromi Yoshida, Shigehiro Kamitori, Toshifumi Takao, Keiji Oguma, Atsushi Nishikawa

    ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS　Vol. 70　No. 1　p. 64-67　2014/01　Research paper (scientific journal)

  44. Affinity-trap polyacrylamide gel electrophoresis: A novel method of capturing specific proteins by electro-transfer

    Awada Chihiro, Takao Toshifumi

    SEIBUTSU BUTSURI KAGAKU　Vol. 58　No. 2　p. 30-32　2014

    Publisher: Japanese Electrophoresis Society

  45. Chemoenzymatic synthesis of the immunoglobulin domain of tim-3 carrying a complex-type N-glycan by using a one-pot ligation

    Yuya Asahina, Shigehiro Kamitori, Toshifumi Takao, Nozomu Nishi, Hironobu Hojo

    Angewandte Chemie - International Edition　Vol. 52　No. 37　p. 9733-9737　2013/09/09　Research paper (scientific journal)

    Publisher: Wiley

  46. Identification of Cargo Proteins Specific for Importin-beta with Importin-alpha Applying a Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based in Vitro Transport System

    Makoto Kimura, Nobuaki Okumura, Shingo Kose, Toshifumi Takao, Naoko Imamoto

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 288　No. 34　p. 24540-24549　2013/08　Research paper (scientific journal)

  47. The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by different mechanisms

    Hideki Yamamoto, Chihiro Awada, Hideaki Hanaki, Hiroshi Sakane, Ikuko Tsujimoto, Yuko Takahashi, Toshifumi Takao, Akira Kikuchi

    JOURNAL OF CELL SCIENCE　Vol. 126　No. 13　p. 2931-2943　2013/07　Research paper (scientific journal)

  48. Diversity in protein profiles of individual calcium oxalate kidney stones.

    Nobuaki Okumura, Masao Tsujihata, Chikahiro Momohara, Iwao Yoshioka, Kouzou Suto, Norio Nonomura, Akihiko Okuyama, Toshifumi Takao

    PloS one　Vol. 8　No. 7　2013　Research paper (scientific journal)

  49. Identification of Cargo Proteins Specific for the Nucleocytoplasmic Transport Carrier Transportin by Combination of an in Vitro Transport System and Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Quantitative Proteomics

    Makoto Kimura, Shingo Kose, Nobuaki Okumura, Kenichiro Imai, Maiko Furuta, Noriyuki Sakiyama, Kentaro Tomii, Paul Horton, Toshifumi Takao, Naoko Imamoto

    MOLECULAR & CELLULAR PROTEOMICS　Vol. 12　No. 1　p. 145-157　2013/01　Research paper (scientific journal)

  50. Quantitative Analysis of Deamidation and Isomerization in beta(2)-Microglobulin by O-18 Labeling

    Masafumi Fukuda, Toshifumi Takao

    ANALYTICAL CHEMISTRY　Vol. 84　No. 23　p. 10388-10394　2012/12　Research paper (scientific journal)

  51. Significance of alanine aminopeptidase N (APN) in bile in the diagnosis of acute cellular rejection after liver transplantation

    Chiwan Kim, Shintaro Aono, Shigeru Marubashi, Hiroshi Wada, Shogo Kobayashi, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Nobuaki Okumura, Toshifumi Takao, Yuichiro Doki, Masaki Mori, Hiroaki Nagano

    Journal of Surgical Research　Vol. 175　No. 1　p. 138-148　2012/06/01　Research paper (scientific journal)

  52. Association of aureolic acid antibiotic, chromomycin A3 with Cu 2+ and its negative effect upon DNA binding property of the antibiotic

    Shibojyoti Lahiri, Toshifumi Takao, Pukhrambam Grihanjali Devi, Saptaparni Ghosh, Ayanjeet Ghosh, Amrita Dasgupta, Dipak Dasgupta

    BioMetals　Vol. 25　No. 2　p. 435-450　2012/04　Research paper (scientific journal)

  53. Increasing effect of an oral intake of L-hydroxyproline on the soluble collagen content of skin and collagen fragments in rat serum

    Mami Aoki, Kouzou Suto, Miho Komatsu, Ayako Kamimura, Koji Morishita, Motoo Yamasaki, Toshifumi Takao

    Bioscience, Biotechnology and Biochemistry　Vol. 76　No. 6　p. 1242-1244　2012　Research paper (scientific journal)

  54. Charge state-selective separation of peptides by reversible modification of amino groups and strong cation-exchange chromatography: Evaluation in proteomic studies using peptide-centric database searches

    Lazaro H. Betancourt, Aniel Sanchez, Yasset Perez, Jorge Fernandez de Cossio, Jeovanis Gil, Patricia Toledo, Seiji Iguchi, Saburo Aimoto, Luis J. Gonzalez, Gabriel Padron, Toshifumi Takao, Vladimir Besada

    JOURNAL OF PROTEOMICS　Vol. 74　No. 10　p. 2210-2213　2011/09　Research paper (scientific journal)

  55. Distribution of neuroendocrine regulatory peptide-1 and-2, and proteolytic processing of their precursor VGF protein in the rat

    Emi Mishiro-Sato, Kazuki Sasaki, Takashi Matsuo, Haruaki Kageyama, Hideki Yamaguchi, Yukari Date, Masako Matsubara, Takehiro Ishizu, Kumiko Yoshizawa-Kumagaye, Yoshinori Satomi, Toshifumi Takao, Seiji Shioda, Masamitsu Nakazato, Naoto Minamino

    JOURNAL OF NEUROCHEMISTRY　Vol. 114　No. 4　p. 1097-1106　2010/08　Research paper (scientific journal)

  56. Affinity-Trap Polyacrylamide Gel Electrophoresis Using Phos-tag for Phosphoprotein Profiling

    Abstracts for Annual Meeting of Japanese Proteomics Society　Vol. 2010　p. 86-86　2010

    Publisher: Japanese Proteomics Society (Japan Human Proteome Organisation)

  57. [Urinary peptidomics].

    Nobuaki Okumura, Kozo Sudo, Toshifumi Takao

    Nihon Jinzo Gakkai shi　Vol. 52　No. 4　p. 485-8　2010　Research paper (scientific journal)

  58. Expression of C4.4A at the invasive front is a novel prognostic marker for disease recurrence of colorectal cancer

    Ken Konishi, Hirofumi Yamamoto, Koshi Mimori, Ichiro Takemasa, Tsunekazu Mizushima, Masataka Ikeda, Mitsugu Sekimoto, Nariaki Matsuura, Toshifumi Takao, Yuichiro Doki, Masaki Mori

    Cancer Science　Vol. 101　No. 10　p. 2269-2277　2010　Research paper (scientific journal)

    Publisher: Blackwell Publishing Ltd

  59. Mitocryptide-2: Purification, identification, and characterization of a novel cryptide that activates neutrophils

    Hidehito Mukai, Tetsuo Seki, Hiroko Nakano, Yoshinori Hokari, Toshifumi Takao, Masanori Kawanami, Hiroyuki Tsukagoshi, Hirokazu Kimura, Yoshiaki Kiso, Yasutsugu Shimonishi, Yoshisuke Nishi, Eisuke Munekata

    Journal of Immunology　Vol. 182　No. 8　p. 5072-5080　2009/04/15　Research paper (scientific journal)

  60. The amino-terminal region of Atg3 is essential for association with phosphatidylethanolamine in Atg8 lipidation

    Takao Hanada, Yoshinori Satomi, Toshifumi Takao, Yoshinori Ohsumi

    FEBS LETTERS　Vol. 583　No. 7　p. 1078-1083　2009/04　Research paper (scientific journal)

  61. Discovery of mitocryptide-1, a neutrophil-activating cryptide from healthy porcine heart

    Hidehito Mukai, Yoshinori Hokari, Tetsuo Seki, Toshifumi Takao, Makoto Kubota, Yuko Matsuo, Hiroyuki Tsukagoshi, Masahiko Kato, Hirokazu Kimura, Yasutsugu Shimonishi, Yoshiaki Kiso, Yoshisuke Nishi, Kaori Wakamatsu, Eisuke Munekata

    Journal of Biological Chemistry　Vol. 283　No. 45　p. 30596-30605　2008/11/07　Research paper (scientific journal)

  62. Evidence for phosphorylation of rat liver glucose-regulated protein 58, GRP58/ERp57/ER-60, induced by fasting and leptin.

    Kanako Kita, Nobuaki Okumura, Toshifumi Takao, Makoto Watanabe, Toshiya Matsubara, Osamu Nishimura, Katsuya Nagai

    FEBS letters　Vol. 580　No. 1　p. 199-205　2006/01/09　Research paper (scientific journal)

  63. 'Information-based-acquisition' (IBA) technique with an ion-trap/time-of-flight mass spectrometer for high-throughput and reliable protein profiling

    Toshiyuki Yokosuka, Kiyomi Yoshinari, Kinya Kobayashi, Atsushi Ohtake, Atsumu Hirabayashi, Yuichiro Hashimoto, Izumi Waki, Toshifumi Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 20　No. 17　p. 2589-2595　2006　Research paper (scientific journal)

  64. Three maize leaf ferredoxin:NADPH oxidoreductases vary in subchloroplast location, expression, and interaction with ferredoxin.

    Okutani S, Hanke GT, Satomi Y, Takao T, Kurisu G, Suzuki A, Hase T

    Plant physiology　Vol. 139　No. 3　p. 1451-1459　2005/11

  65. Identification of a novel p300-specific-associating protein, PRS1 (phosphoribosylpyrophosphate synthetase subunit 1).

    Atsushi Kaida, Yasuo Ariumi, Keiko Baba, Masami Matsubae, Toshifumi Takao, Kunitada Shimotohno

    The Biochemical journal　Vol. 391　No. Pt 2　p. 239-47　2005/10/15　Research paper (scientific journal)

  66. Multiple iso-proteins of FNR in Arabidopsis: evidence for different contributions to chloroplast function and nitrogen assimilation

    GT Hanke, S Okutani, Y Satomi, T Takao, A Suzuki, T Hase

    PLANT CELL AND ENVIRONMENT　Vol. 28　No. 9　p. 1146-1157　2005/09　Research paper (scientific journal)

  67. Farnesylation of retinal transducin underlies its translocation during light adaptation

    H. Kassai, A. Aiba, K. Nakao, K. Nakamura, M. Katsuki, W.-H. Xiong, K.-W. Yau, H. Imai, Y. Shichida, Y. Satomi, T. Takao, T. Okano, Y. Fukada

    Neuron　Vol. 47　No. 4　p. 529-539　2005/08/18

  68. Erratum: Isolation and characterization of four VIP-related peptides from red-bellied newt, Cynops pyrrhogaster (Regulatory Peptides (2004) 123 (173-179) PII: S0167011504001648 and DOI: 10.1016/j.regpep.2004.04.024)

    Hitoshi Teranishi, Yojiro Muneoka, Toshifumi Takao, Yasutsugu Shimonishi, Masayasu Kojima

    Regulatory Peptides　Vol. 129　No. 1-3　2005/07/15　Research paper (scientific journal)

  69. Proteomic analysis of slow- and fast-twitch skeletal muscles.

    Nobuaki Okumura, Akiko Hashida-Okumura, Kanako Kita, Masami Matsubae, Toshiya Matsubara, Toshifumi Takao, Katsuya Nagai

    Proteomics　Vol. 5　No. 11　p. 2896-906　2005/07　Research paper (scientific journal)

  70. Placental and intestinal alkaline phosphatases are receptors for Aeromonas sobria hemolysin.

    Akihiro Wada, Ai-Ping Wang, Hajime Isomoto, Yoshinori Satomi, Toshifumi Takao, Akira Takahashi, Shizuka Awata, Tomohiko Nomura, Yoshio Fujii, Shigeru Kohno, Keinosuke Okamoto, Joel Moss, José Luis Millán, Toshiya Hirayama

    International journal of medical microbiology : IJMM　Vol. 294　No. 7　p. 427-35　2005/01　Research paper (scientific journal)

  71. Accurate mass measurement in nano-electrospray ionization mass spectrometry by alternate switching of high voltage between sample and reference sprayers

    Y Satomi, Y Kudo, K Sasaki, T Hase, T Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 19　No. 4　p. 540-546　2005　Research paper (scientific journal)

  72. Isolation and characterization of four VIP-related peptides from red-bellied newt, Cynops pyrrhogaster

    H Teranishi, Y Muneoka, T Takao, Y Shimonishi, M Kojima

    REGULATORY PEPTIDES　Vol. 123　No. 1-3　p. 173-179　2004/12　Research paper (scientific journal)

  73. N-glycosylation at Asn(491) in the Asn-Xaa-Cys motif of human transferrin

    Y Satomi, Y Shimonishi, T Takao

    FEBS LETTERS　Vol. 576　No. 1-2　p. 51-56　2004/10　Research paper (scientific journal)

  74. Role of KaiC phosphorylation in the circadian clock system of Synechococcus elongatus PCC 7942

    T Nishiwaki, Y Satomi, M Nakajima, C Lee, R Kiyohara, H Kageyama, Y Kitayama, M Temamoto, A Yamaguchi, A Hijikata, M Go, H Iwasaki, T Takao, T Kondo

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 101　No. 38　p. 13927-13932　2004/09　Research paper (scientific journal)

  75. Site-specific carbohydrate profiling of human transferrin by nano-flow liquid chromatography/electrospray ionization mass spectrometry

    Y Satomi, Y Shimonishi, T Hase, T Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 18　No. 24　p. 2983-2988　2004　Research paper (scientific journal)

  76. Automated interpretation of mass spectra of complex mixtures by matching of isotope peak distributions

    J Fernandez-De-Cossio, LJ Gonzalez, Y Satomi, L Betancourt, Y Ramos, Huerta, V, Besada, V, G Padron, N Minamino, T Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 18　No. 20　p. 2465-2472　2004　Research paper (scientific journal)

  77. Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks

    A Konishi, S Shimizu, J Hirota, T Takao, YH Fan, Y Matsuoka, LL Zhang, Y Yoneda, Y Fujii, AI Skouitchi, Y Tsujimoto

    CELL　Vol. 114　No. 6　p. 673-688　2003/09　Research paper (scientific journal)

  78. Determination of endogenous peptides in the porcine brain: possible construction of Peptidome, a fact database for endogenous peptides

    N Minamino, J Tanaka, H Kuwahara, T Kihara, Y Satomi, M Matsubae, T Takao

    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES　Vol. 792　No. 1　p. 33-48　2003/07　Research paper (scientific journal)

  79. Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate.

    Mizushima N, Kuma A, Kobayashi Y, Yamamoto A, Matsubae M, Takao T, Natsume T, Ohsumi Y, Yoshimori T

    Journal of cell science　Vol. 116　No. Pt 9　p. 1679-1688　2003/05

  80. Molecular cloning and characterization of TPP36 and its isoform TPP32, novel substrates of Abl tyrosine kinase.

    Kiichiro Tsuchiya, Youhei Kawano, Toshiyuki Kojima, Kisaburo Nagata, Toshifumi Takao, Masato Okada, Hisaaki Shinohara, Kazushige Maki, Noriko Toyama-Sorimachi, Nobuyuki Miyasaka, Mamoru Watanabe, Hajime Karasuyama

    FEBS Lett.　Vol. 537　No. 1-3　p. 203-209　2003/02　Research paper (scientific journal)

  81. Peptidome, the fact-database for endogenous peptides: Its construction and application

    Minamino N., Tanaka J., Kuwahara H., Matsubae M., Takao T., Isoyama M.

    Abstracts for Annual Meeting of Japanese Proteomics Society　Vol. 2003　p. 26-26　2003

    Publisher: Japanese Proteomics Society (Japan Human Proteome Organisation)

  82. Mass Spectrometry and Proteomics Research

    Takao Toshifumi

    tits　Vol. 8　No. 2　p. 60-61　2003

    Publisher: Japan Science Support Foundation

  83. epsilon-N,N,N-Trimethyllysine-specific ions in matrix-assisted laser desorption/ionization-tandem mass spectrometry

    J Hirota, Y Satomi, K Yoshikawa, T Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 17　No. 5　p. 371-376　2003　Research paper (scientific journal)

  84. Preparation and Characterization of Monoclonal Antibodies Specific for Lauroylated Isoform of Bovine Transducin α-Subunit: Immunohistochemical Analysis of Bovine Retinas

    Osamu Shouno, Koichi Kokame, Masasuke Araki, Toshifumi Takao, Yasutsugu Shimonishi, Masayuki Murata, Tôru Yoshizawa, Yoshitaka Fukada

    Journal of Neurochemistry　Vol. 66　No. 5　p. 2188-2196　2002/11/23　Research paper (scientific journal)

    Publisher: Wiley

  85. Association of Pasteurella multocidatoxin with vimentin.

    Shime Hiroaki, Ohnishi Takahiro, Nagao Kaori, Oka Kiyomasa, Takao Toshifumi, Horiguchi Yasuhiko

    Infection and immunity　Vol. 70　No. 11　p. 6460-6463　2002/11　Research paper (scientific journal)

  86. Interaction of the SH2 Domain of Fyn with a Cytoskeletal Protein, β-Adducin

    Takaki Shima, Nobuaki Okumura, Toshifumi Takao, Yoshinori Satomi, Takeshi Yagi, Masato Okada, Katsuya Nagai

    Journal of Biological Chemistry　Vol. 276　No. 45　p. 42233-42240　2001/11/09　Research paper (scientific journal)

  87. Erratum: Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by toll-like receptor 2: Role of N-terminal hydrophobic portion in its multiple functions (The Journal of Immunology (2001) 166 (2610-2616))

    M. Nishiguchi, M. Matsumoto, T. Takao, M. Hoshino, Y. Shimonishi, S. Tsuji, N. A. Begum, O. Takeuchi, S. Akira, Y. Nishizawa, K. Toyoshima, T. Seya

    Journal of Immunology　Vol. 167　No. 6　2001/09/15　Research paper (scientific journal)

  88. O-Glycosylation of G-protein-coupled receptor, octopus rhodopsin - Direct analysis by FAB mass spectrometry

    M Nakagawa, T Miyamoto, R Kusakabe, S Takasaki, T Takao, Y Shichida, M Tsuda

    FEBS LETTERS　Vol. 496　No. 1　p. 19-24　2001/05　Research paper (scientific journal)

  89. Selective isolation and identification of N-terminal blocked peptides from tryptic protein digests

    L Betancourt, Besada, V, LJ Gonzalez, Morera, V, G Padron, T Takao, Y Shimonishi

    JOURNAL OF PEPTIDE RESEARCH　Vol. 57　No. 5　p. 345-353　2001/05　Research paper (scientific journal)

  90. Accurate peptide sequencing by mass spectrometry

    T Takao, W Mo, J Fernandez-de-Cossio, J Gonzalez, Besada, V, G Padron, Y Shimonishi

    PEPTIDE SCIENCE - PRESENT AND FUTURE　p. 146-151　1999　Research paper (international conference proceedings)

  91. Amino acid sequence of a peptide that inhibits human lymphocyte proliferation induced by the superantigen Yersinia pseudotuberculosis-derived mitogen

    Ken Ichi Yoshino, Toshifumi Takao, Makiko Ishibashi, Yuji Samejima, Yasutsugu Shimonishi, Tae Takeda

    Japanese Journal of Medical Science and Biology　Vol. 49　No. 5-6　p. 256-257　1996/10　Research paper (international conference proceedings)

  92. Bioactive peptides isolated from an African ancient-type fish, Polypterus senegalus

    S Kinjo, H Teranishi, M Ohtani, T Takahashi, Y Muneoka, T Takao, Y Shimonishi

    PEPTIDE CHEMISTRY 1995　p. 189-192　1996　Research paper (international conference proceedings)

  93. KERAMAMIDES E, G, H, AND J, NEW CYCLIC PEPTIDES CONTAINING ON OXAZOLE OR A THIAZOLE RING FROM A THEONELLA SPONGE

    H SHIGEMORI, F ITAGAKI, T TAKAO, Y SHIMONISHI, J KOBAYASHI

    PEPTIDE CHEMISTRY 1994　p. 17-20　1995　Research paper (international conference proceedings)

  94. Amino acid sequence of a novel heat-stable enterotoxin produced by a yst gene-negative strain of Yersinia enterocolitica

    Ken ichi Yoshino, Huang Xiaozhe, Miki Miyachi, Yeong Man Hong, Toshifumi Takao, Hiroshi Nakao, Tae Takeda, Yasutsugu Shimonishi

    Letters in Peptide Science　Vol. 1　No. 2　p. 95-105　1994/10　Research paper (scientific journal)

  95. Purification and protein chemical characterization of a novel superantigen produced by a Yersinia pseudotuberculosis strain

    I. Yoshino, J. Abe, H. Murata, T. Takao, T. Kohsaka, Y. Shimonishi, T. Takeda

    Japanese Journal of Medical Science and Biology　Vol. 47　No. 5-6　p. 298-299　1994　Research paper (international conference proceedings)

  96. AN INVERTEBRATE-TYPE TACHYKININ ISOLATED FROM THE FRESH-WATER BIVALVE MOLLUSK, ANODONTA-CYGNEA

    Y FUJISAWA, Y MUNEOKA, T TAKAHASHI, T TAKAO, Y SHIMONISHI, KUBOTA, I, T IKEDA, H MINAKATA, K NOMOTO, T KISS, L HIRIPI

    PEPTIDE CHEMISTRY 1993　p. 161-164　1994　Research paper (international conference proceedings)

  97. Structural elucidation of aibellin, a new peptide antibiotic with efficiency enhancing activity on rumen fermentation.

    KUMAZAWA SHIGENORI, KANDA MINA, AOYAMA HIDEYUKI, UTAGAWA MASAMI, KONDO JUN, SAKAMOTO SEIKO, OHTANI HIROYUKI, MIKAWA TAKASHI, CHIGA ISAO, HAYASE TETSUO, HINO TSUNEO, TAKAO TOSHIFUMI, SHIMONISHI YASUTSUGU

    The Japanese Journal of Antibiotics　Vol. 47　No. 10　p. 1136-1144　1994

    Publisher: JAPAN ANTIBIOTICS RESEARCH ASSOCIATION

  98. SYNTHESIS AND MASS-SPECTROMETRIC ANALYSIS OF PNA OLIGOMERS

    H FUKUDA, T TAKAO, J COULL, Y SHIMONISHI

    PEPTIDE CHEMISTRY 1993　p. 45-48　1994　Research paper (international conference proceedings)

  99. DETERMINATION OF POSTTRANSLATIONAL MODIFICATIONS BY MASS-SPECTROMETRY

    T TAKAO, Y SHIMONISHI

    METHODS IN PROTEIN SEQUENCE ANALYSIS　p. 157-164　1993　Research paper (international conference proceedings)

  100. A new type of mitogenic factor produced by Streptococcus pyogenes

    Takashi Yutsudo, Hitoshi Murai, Javier Gonzalez, Toshifumi Takao, Yasutsugu Shimonishi, Yoshifumi Takeda, Hisanaga Igarashi, Yorio Hinuma

    FEBS Letters　Vol. 308　No. 1　p. 30-34　1992/08/10　Research paper (scientific journal)

  101. Sperm-activating peptide type-V (SAP-V), a fifth member of the sperm-activating peptide family, purified from the egg-conditioned media of the heart urchin Brissus agassizii

    Ken ichi Yoshino, Toshifumi Takao, Yasutsugu Shimonishi, Norio Suzuki

    Comparative Biochemistry and Physiology -- Part B: Biochemistry and　Vol. 102　No. 4　p. 691-700　1992/08　Research paper (scientific journal)

  102. Determination of posttranslational modifications by mass spectrometry

    Toshifumi Takao, Yasutsugu Shimonishi

    Journal of Protein Chemistry　Vol. 11　No. 4　p. 374-375　1992/08　Research paper (scientific journal)

    Publisher: Kluwer Academic Publishers-Plenum Publishers

  103. Rapid identification of N-glycosylation sites in a glycoprotein by collision-induced dissociation mass spectrometry

    Javier Gonzalez, Toshifumi Takao, Vladimir Besada, Rolando Rodriguez, Gabriel Padron, Yasutsugu Shimonishi

    Journal of Protein Chemistry　Vol. 11　No. 4　p. 375-376　1992/08　Research paper (scientific journal)

    Publisher: Kluwer Academic Publishers-Plenum Publishers

  104. A METHOD FOR DETERMINATION OF N-GLYCOSYLATION SITES IN GLYCOPROTEINS BY COLLISION-INDUCED DISSOCIATION ANALYSIS IN FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY - IDENTIFICATION OF THE POSITIONS OF CARBOHYDRATE-LINKED ASPARAGINE IN RECOMBINANT ALPHA-AMYLASE BY TREATMENT WITH PEPTIDE-N-GLYCOSIDASE-F IN O-18-LABELED WATER

    J GONZALEZ, T TAKAO, H HORI, BESADA, V, R RODRIGUEZ, G PADRON, Y SHIMONISHI

    ANALYTICAL BIOCHEMISTRY　Vol. 205　No. 1　p. 151-158　1992/08　Research paper (scientific journal)

  105. SYNTHESIS AND BIOLOGICAL FUNCTION OF THE C-TERMINAL FARNESYLATED PEPTIDE OF THE GAMMA-SUBUNIT OF PHOTORECEPTOR GTP-BINDING PROTEIN

    M FUKUDA, T TAKAO, Y HIDAKA, T MATSUDA, Y FUKADA, T AKINO, T YOSHIZAWA, Y SHIMONISHI

    PEPTIDE CHEMISTRY 1991　p. 259-264　1992　Research paper (international conference proceedings)

  106. DETERMINATION OF THE AMINO-ACID-SEQUENCE OF AN INTRAMOLECULAR DISULFIDE LINKAGE-CONTAINING SPERM-ACTIVATING PEPTIDE BY TANDEM MASS-SPECTROMETRY

    K YOSHINO, T TAKAO, Y SHIMONISHI, N SUZUKI

    FEBS LETTERS　Vol. 294　No. 3　p. 179-182　1991/12　Research paper (scientific journal)

  107. DETERMINATION OF POSTTRANSLATIONALLY MODIFIED STRUCTURES IN PROTEINS BY ACCURATE MASS MEASUREMENT IN FAB MASS-SPECTROMETRY

    T TAKAO, Y FUKADA, H OHGURO, T YOSHIZAWA, T AKINO, Y SHIMONISHI

    PEPTIDE CHEMISTRY 1990　p. 165-170　1991　Research paper (international conference proceedings)

  108. Analysis of post‐translational modifications of proteins by accurate mass measurement in fast atom bombardment mass spectrometry

    Toshifumi Takao, Ken‐ichi ‐i Yoshino, Norio Suzuki, Yasutsugu Shimonishi

    Biological Mass Spectrometry　Vol. 19　No. 11　p. 705-712　1990/11　Research paper (scientific journal)

  109. The NH2-terminal residues of rat liver proteasome (multicatalytic proteinase complex) subunits, C2, C3 and C8, are Nα-acetylated

    Fuminori Tokunaga, Rie Aruga, Sadaaki Iwanaga, Keiji Tanaka, Akira Ichihara, Toshifumi Takao, Yasutsugu Shimonishi

    FEBS Letters　Vol. 263　No. 2　p. 373-375　1990/04/24　Research paper (scientific journal)

  110. Occurrence of S‐(1,2‐dicarboxyethyl)‐cysteine at position 77 in mutant human lysozyme secreted by Saccharomyces cerevisiae

    Masakazu KIKUCHI, Yoshio TANIYAMA, Shigenori KANAYA, Toshifumi TAKAO, Yasutsugu SHIMONISHI

    European Journal of Biochemistry　Vol. 187　No. 2　p. 315-320　1990　Research paper (scientific journal)

  111. A species-specific sperm-activating peptide from the egg jelly of the sea urchin Diadema setosum

    Ken Ichi Yoshino, Masanori Kurita, Masaaki Yamaguchi, Kohji Nomura, Toshifumi Takao, Yasutsugu Shimonishi, Norio Suzuki

    Comparative Biochemistry and Physiology -- Part B: Biochemistry and　Vol. 95　No. 2　p. 423-429　1990　Research paper (scientific journal)

  112. Derivatives of sperm-activating peptide III (SAP-III) associated with eggs of sand dollars, Clypeaster japonicus and Astriclypeus manni

    Ken ichi Yoshino, Toshifumi Takao, Masaaki Yamaguchi, Yasutsugu Shimonishi, Norio Suzuki

    Comparative Biochemistry and Physiology -- Part B: Biochemistry and　Vol. 97　No. 4　p. 679-685　1990　Research paper (scientific journal)

  113. Antimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: Chemical structures and biological activity

    Toshiyuki Miyata, Fuminori Tokunaga, Takashi Yoneya, Katsuhiro Yoshikawa, Sadaaki Iwanaga, Makoto Niwa, Toshifumi Takao, Yasutsugu Shimonishi

    Journal of Biochemistry　Vol. 106　No. 4　p. 663-668　1989　Research paper (scientific journal)

    Publisher: Oxford University Press

  114. A halogenated amino acid-containing sperm activating peptide and its related peptides isolated from the egg jelly of sea urchins, Tripneustes gratilla, Pseudoboletia maculata, Strongylocentrotus nudus, Echinometra mathaei and Heterocentrotus mammillatus

    Ken Ichi Yoshino, Hiroko Kajiura, Kohji Nomura, Toshifumi Takao, Yasutsugu Shimonishi, Masanori Kurita, Masaaki Yamaguchi, Norio Suzuki

    Comparative Biochemistry and Physiology -- Part B: Biochemistry and　Vol. 94　No. 4　p. 739-751　1989　Research paper (scientific journal)

  115. BOVINE FACTOR-VII - ITS PURIFICATION AND COMPLETE AMINO-ACID SEQUENCE

    H TAKEYA, S KAWABATA, K NAKAGAWA, Y YAMAMICHI, T MIYATA, S IWANAGA, T TAKAO, Y SHIMONISHI

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 263　No. 29　p. 14868-14877　1988/10　Research paper (scientific journal)

  116. Amino acid sequence of heat-stable enterotoxin produced by Vibrio cholerae non-01

    Toshifumi Takao, Yasutsugu Shimonishi, Makoto Kobayashi, Osamu Nishimura, Michiko Arita, Tae Takeda, Takeshi Honda, Toshio Miwatani

    FEBS Letters　Vol. 193　No. 2　p. 250-254　1985/12/02　Research paper (scientific journal)

  117. Application of S-1-adamantylcysteine to the synthesis of a 37-residue peptide amide corresponding to human calcitonin gene-related peptide (hCGRP)

    Nobutaka Fujii, Haruaki Yajima, Akira Otaka, Susumu Funakoshi, Motoyoshi Nomizu, Kenichi Akaji, Itsuo Yamamoto, Kanji Torizuka, Kouki Kitagawa, Tadashi Akita, Kenshi Ando, Tatsuhiko Kawamoto, Yasutsugu Shimonishi, Toshifumi Takao

    Journal of the Chemical Society, Chemical Communications　No. 9　p. 602-603　1985　Research paper (scientific journal)

  118. AMINO-ACID SEQUENCES OF ALLOPHYCOCYANIN ALPHA-SUBUNITS AND BETA-SUBUNITS ISOLATED FROM ANABAENA-CYLINDRICA - PRESENCE OF AN UNKNOWN DERIVATIVE OF ASPARTIC-ACID IN THE BETA-SUBUNIT

    Y MINAMI, F YAMADA, T HASE, H MATSUBARA, A MURAKAMI, Y FUJITA, T TAKAO, Y SHIMONISHI

    FEBS LETTERS　Vol. 191　No. 2　p. 216-220　1985　Research paper (scientific journal)

  119. Fast atom bombardment (FAB) mass spectra of protein digests: Hen and duck egg‐white lysozymes

    Toshifumi Takao, Masakuni Yoshida, Yeong‐Man Hong, Saburo Aimoto, Yasutsugu Shimonishi

    Biological Mass Spectrometry　Vol. 11　No. 11　p. 549-556　1984　Research paper (scientific journal)

  120. SIMULTANEOUS ANALYSIS OF C-TERMINAL AMINO-ACID-RESIDUES OF PEPTIDE MIXTURES BY COMBINATION OF FIELD DESORPTION MASS-SPECTROMETRY AND CARBOXYPEPTIDASE DIGESTION

    Y HONG, T TAKAO, S AIMOTO, Y SHIMONISHI

    BIOMEDICAL MASS SPECTROMETRY　Vol. 10　No. 8　p. 450-457　1983　Research paper (scientific journal)

  121. A New Method for CarboxyLTerminal Sequence Analysis of a Peptide Using Carboxypeptidases and Field'desorption Mass Spectrometry

    Yasutsugu Shimonishi, Yeong-Man Hong, Toshifumi Takao, Saburo Aimoto, Yoshiharu Izumi, Yasutsugu Shimonishi, Hisashi Matsuda

    Proceedings of the Japan Academy Series B: Physical and Biological Sciences　Vol. 57　No. 8　p. 304-308　1981　Research paper (scientific journal)

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    ペプチド討論会講演要旨集　Vol. 57th　2020

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    N. Itai, R. Okabe, T. Shimazu, T. Takao, Y. Kaburagi, T. Dohi, T. Tonozuka, A. Nishikawa

    MOLECULAR BIOLOGY OF THE CELL　Vol. 26　2015　Research paper, summary (international conference)

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    貝森 淳哉, 前原 一満, 畑中 雅喜, 小尾 佳嗣, 津田 秀年, 山本 聡子, 市丸 直嗣, 楽木 宏実, 高原 史郎, 大川 恭行, 高尾 敏文, 木村 宏, 猪阪 善隆

    日本腎臓学会誌　Vol. 56　No. 3　p. 415-415　2014/05

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    WAKABAYASHI Masaki, SASAKI Kazuki, OSAKI Tsukasa, SATOMI Yoshinori, TAKAO Toshifumi, MINAMINO Naoto

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    Vol. 2010　p. 105-105　2011/03/01

  8. A screen for potential ferredoxin electron transfer partners uncovers new, redox dependent interactions

    G. T. Hanke, Y. Satomi, K. Shinmura, T. Takao, T. Hase

    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS　Vol. 1814　No. 2　p. 366-374　2011/02

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    山本英樹, 粟田ちひろ, 高尾敏文, 岸田昭世, 岸田想子, 菊池章

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    Emi Mishiro, Kazuki Sasaki, Hideki Yamaguchi, Masamitsu Nakazato, Yoshinori Satomi, Toshifumi Takao, Naoto Minamino

    ENDOCRINE JOURNAL　Vol. 57　p. S441-S442　2010/03　Research paper, summary (international conference)

  11. Peptide profiling of human urine for biomarker discovery

    Toshifumi Takao

    Seikagaku　Vol. 82　No. 6　p. 533-540　2010　Book review, literature introduction, etc.

  12. Affinity-Trap Polyacrylamide Gel Electrophoresis: A Novel Method of Capturing Specific Proteins by Electro-Transfer

    Chihiro Awada, Takashi Sato, Toshifumi Takao

    ANALYTICAL CHEMISTRY　Vol. 82　No. 2　p. 755-761　2010/01

  13. 新規生理活性ペプチドNERPsのラットにおける内在性と前駆体VGFのプロセッシングの全体像

    三城 恵美, 佐々木 一樹, 松尾 崇, 山口 秀樹, 中里 雅光, 影山 晴秋, 塩田 清二, 里見 佳典, 高尾 敏文, 南野 直人

    日本生化学会大会プログラム・講演要旨集　Vol. 82回　p. 2T4a-1　2009/09

    Publisher: (公社)日本生化学会

  14. 概日時計の異なる段階におけるCLOCKとBMAL1の周期的リン酸化(Rhythmic phosphorylation of CLOCK and BMAL1 at different phases of circadian clock)

    吉種 光, 高尾 敏文, ズ・ゴク・ヒエン, 岡野 俊行, 深田 吉孝

    日本生化学会大会プログラム・講演要旨集　Vol. 82回　p. 4P-461　2009/09

    Publisher: (公社)日本生化学会

  15. CKI epsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

    Yasushi Isojima, Masato Nakajima, Hideki Ukai, Hiroshi Fujishima, Rikuhiro G. Yamada, Koh-hei Masumoto, Reiko Kiuchi, Mayumi Ishida, Maki Ukai-Tadenuma, Yoichi Minami, Ryotaku Kito, Kazuki Nakao, Wataru Kishimoto, Seung-Hee Yoo, Kazuhiro Shimomura, Toshifumi Takao, Atsuko Takano, Toshio Kojima, Katsuya Nagai, Yoshiyuki Sakaki, Joseph S. Takahashi, Hiroki R. Ueda

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 106　No. 37　p. 15744-15749　2009/09

  16. Snapshot Peptidomics of the Regulated Secretory Pathway

    Kazuki Sasaki, Yoshinori Satomi, Toshifumi Takao, Naoto Minamino

    MOLECULAR & CELLULAR PROTEOMICS　Vol. 8　No. 7　p. 1638-1647　2009/07

  17. Utilization of Fluorescent Labeled Analogs Designed based on "Camouflaging Substitution" for SAR of Phenoloxidase Inhibitor, POI

    YOSHIDA Rinako, AWADA Chihiro, TAKAO Toshifumi, SATO Takashi

    Vol. 2008　p. 37-40　2009/03/01

  18. Involvement of linear polyubiquitylation of NEMO in NF-kappa B activation

    Fuminori Tokunaga, Shin-ichi Sakata, Yasushi Saeki, Yoshinori Satomi, Takayoshi Kirisako, Kiyoko Kamei, Tomoko Nakagawa, Michiko Kato, Shigeo Murata, Shoji Yamaoka, Masahiro Yamamoto, Shizuo Akira, Toshifumi Takao, Keiji Tanaka, Kazuhiro Iwai

    NATURE CELL BIOLOGY　Vol. 11　No. 2　p. 123-U40　2009/02

  19. Ser38/Ser42 phosphorylation of CLOCK critical for its DNA-binding and suppression of E-box-dependent transcription

    吉種光, 高尾敏文, 里見佳典, ズ ゴク‐ヒエン, 岡野俊行, 深田吉孝

    Program Abstr 6th Congr Asian Sleep Res Soc 34th Annu Meet Jpn Soc Sleep Res 16th Annu Meet Jpn Soc Chronobiol Jt Congr 2009　2009

  20. Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription.

    Hikari Yoshitane, Toshifumi Takao, Yoshinori Satomi, Ngoc-Hien Du, Toshiyuki Okano, Yoshitaka Fukada

    Mol. Cell. Biol.　Vol. 29　No. 13　p. 3675-3686　2009

  21. Metalation States versus Enzyme Activities of Cu, Zn-Superoxide Dismutase Probed by Electrospray Ionization Mass Spectrometry

    Yuzo Yamazaki, Toshifumi Takao

    ANALYTICAL CHEMISTRY　Vol. 80　No. 21　p. 8246-8252　2008/11

  22. CKIεによるPERIOD2リン酸化反応の温度依存性

    中嶋正人, 礒島康史, 石田真弓, 鵜飼(蓼沼)磨貴, 鵜飼英樹, 高尾敏文, 高野敦子, 永井克也, 上田泰己

    時間生物学　Vol. 14　No. 2　2008/10/20

  23. 視床下部・下垂体調節機構の新展開 新規生理活性ペプチドNERPの発見と機能解析

    南野 直人, 佐々木 一樹, 山口 秀樹, 里見 佳典, 三城 恵美, 高尾 敏文, 中里 雅光

    日本内分泌学会雑誌　Vol. 84　No. 2　p. 504-504　2008/09

    Publisher: (一社)日本内分泌学会

  24. Analysis of POI-PO interaction using fluorescent labeled analogs designed based on gCamouflaging substitution h

    Rinako Yoshida, Chihiro Awada, Toshifumi Takao, Takashi Sato

    JOURNAL OF PEPTIDE SCIENCE　Vol. 14　No. 8　p. 124-124　2008/08　Research paper, summary (international conference)

  25. 新規生理活性ペプチドNERPの機能解析

    山口 秀樹, 佐々木 一樹, 里見 佳典, 影山 晴秋, 伊達 紫, 十枝内 厚次, Mondal Muhtashan S, 新原 琢也, 松尾 崇, 塩田 清二, 高尾 敏文, 南野 直人, 中里 雅光

    日本内分泌学会雑誌　Vol. 84　No. 1　p. 216-216　2008/04

    Publisher: (一社)日本内分泌学会

  26. Identification of Novel Neuroendocrine Regulatory Peptide 1 and 2 by Peptidome Analysis Strategy

    MINAMINO Naoto, SASAKI Kazuki, SATOMI Yoshinori, YAMAGUCHI Hideki, TAKAO Toshifumi, NAKAZATO Masamitsu

    Vol. 2007　p. 9-12　2008/03/01

  27. 新規生理活性ペプチドNERPのラットにおける生体内分布と内在性分子型

    三城恵美, 佐々木一樹, 山口秀樹, 里見佳典, 石津雄大, 熊谷久美子, 高尾敏文, 中里雅光, 南野直人

    日本内分泌学会雑誌　Vol. 84　No. 1　2008

  28. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

    Takao Hanada, Nobuo N. Noda, Yoshinori Satomi, Yoshinobu Ichimura, Yuko Fujioka, Toshifumi Takao, Fuyuhiko Inagaki, Yoshinori Ohsumi

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 282　No. 52　p. 37298-37302　2007/12

  29. Selective isolation of N-blocked peptides by isocyanate-coupled resin

    Toshiyuki Mikami, Toshifumi Takao

    ANALYTICAL CHEMISTRY　Vol. 79　No. 20　p. 7910-7915　2007/10

  30. 新規水・電解質代謝調節ペプチドNERPの発見と機能解析

    新原 琢也, 山口 秀樹, 佐々木 一樹, 里見 佳典, 影山 晴秋, 塩田 清二, 高尾 敏文, 南野 直人, 中里 雅光

    日本内分泌学会雑誌　Vol. 83　No. 2　p. 587-587　2007/09

    Publisher: (一社)日本内分泌学会

  31. A sequential program of dual phosphorylation of KaiC as a basis for circadian rhythm in cyanobacteria

    Taeko Nishiwaki, Yoshinori Satomi, Yohko Kitayama, Kazuki Terauchi, Reiko Kiyohara, Toshifumi Takao, Takao Kondo

    EMBO JOURNAL　Vol. 26　No. 17　p. 4029-4037　2007/09

  32. Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and-2

    Hideki Yamaguchi, Kazuki Sasaki, Yoshinori Satomi, Takuya Shimbara, Haruaki Kageyama, Muhtashan S. Mondal, Koji Toshinai, Yukari Date, Luis J. Gonzalez, Seiji Shioda, Toshifumi Takao, Masamitsu Nakazato, Naoto Minamino

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 282　No. 36　p. 26354-26360　2007/09

  33. DNA binding and partial nucleoid localization of the chloroplast stromal enzyme ferredoxin : sulfite reductase

    Kohsuke Sekine, Makoto Fujiwara, Masato Nakayama, Toshifumi Takao, Toshiharu Hase, Naoki Sato

    FEBS JOURNAL　Vol. 274　No. 8　p. 2054-2069　2007/04

  34. PEPTIDOME Database and Identification of New Bioactive Peptides

    MINAMINO Naoto, KUWAHARA Hiromiki, SASAKI Kazuki, OSAKI Tsukasa, KIHARA Takahiro, ISOYAMA TANAKA Junko, KATAFUCHI Takeshi, TAKAO Toshifumi, ISOYAMA Masaharu

    Vol. 2006　p. 318-318　2007/03/01

  35. Monounsaturated fatty acid modification of Wnt protein: Its role in Wnt secretion

    Ritsuko Takada, Yoshinori Satomi, Tomoko Kurata, Naoto Ueno, Shigemi Norioka, Hisato Kondoh, Toshifumi Takao, Shinji Takada

    DEVELOPMENTAL CELL　Vol. 11　No. 6　p. 791-801　2006/12

  36. 質量分析法による翻訳後修飾の精密解析〜光シグナル伝達系でのファルネシル化の役割〜

    葛西秀俊, 高尾敏文, 深田吉孝

    細胞工学 特集『プロテオミクスの細胞機能解析への挑戦』秀潤社　Vol. 25　No. 6　p. 608-612　2006

    Publisher: 秀潤社

  37. 質量分析の可能性--未知生体分子の探索ツールとして (特集・構造生物学の現在と今後の展開)

    高尾 敏文

    生体の科学　Vol. 56　No. 6　p. 621-625,図巻頭8　2005/11

    Publisher: 金原一郎記念医学医療振興財団

  38. Corrigendum to "Isolation and characterization of four VIP-related peptides from red-bellied newt, Cynops pyrrhogaster" (vol 123, pg 173, 2004)

    H Teranishi, Y Muneoka, T Takao, Y Shimonishi, M Kojima

    REGULATORY PEPTIDES　Vol. 129　No. 1-3　p. 245-245　2005/07　Other

  39. Frontiers of Proteomics : Aims and Perspectives

    Vol. 77　No. 3　p. 282-288　2005/03/25

    Publisher: 日本生化学会

  40. Identification of ferredoxin binding proteins in Arabidopsis

    G Hanke, Y Satomi, T Takao, T Hase

    PLANT AND CELL PHYSIOLOGY　Vol. 46　p. S69-S69　2005　Research paper, summary (international conference)

  41. Top-Down Analysis of Protein Isoprenylation by Electrospray Ionization Hybrid Quadrupole-TOF Tandem Mass Spectrometry; the Mouse Tgamma Protein.

    Hidetoshi Kassai, Yoshinori Satomi, Yoshitaka Fukada, Toshifumi Takao

    Rapid Commun. Mass Spectrom.　Vol. 19　No. 2　p. 269-274　2005

  42. 蛋白質解析装置 蛋白質の質量分析 (バイオ高性能機器・新技術利用マニュアル) -- (各種解析装置の原理と使用例)

    高尾 敏文

    蛋白質核酸酵素　Vol. 49　No. 11　p. 1541-1545　2004/08

    Publisher: 共立出版

  43. Isotopica: a tool for the calculation and viewing of complex isotopic envelopes (vol 32, pg 2674, 2004)

    J Fernandez-De-Cossio, LJ Gonzalez, Y Satomi, L Betancourt, Y Ramos, Huerta, V, A Amaro, Besada, V, G Padron, N Minamino, T Takao

    NUCLEIC ACIDS RESEARCH　Vol. 32　No. 12　p. 3779-3779　2004/07　Other

  44. Isotopica: a tool for the calculation and viewing of complex isotopic envelopes

    J Fernandez-de-Cossio, LJ Gonzalez, Y Satomi, L Betancourt, Y Ramos, Huerta, V, A Amaro, Besada, V, G Padron, N Minamino, T Takao

    NUCLEIC ACIDS RESEARCH　Vol. 32　p. W674-W678　2004/07

  45. Efficient Data Acquisition System for Peptidome Database

    KUWAHARA Hiromiki, TANAKA(ISOYAMA) Junko, KIHARA Takahiro, MATSUBAE Masami, MATSUI Yasuko, TAKAO Toshifumi, ISOYAMA Masaharu, MINAMINO Naoto

    Vol. 2003　p. 465-466　2004/03/01

  46. Mass Spectrometric Survey of Biological Peptides(Multidisciplinary Search for the Secrets of Eleven-Headed Kannon-Like Biological Functions of Peptide,Symposium,PROCEEDING OF THE 75^<TH> ANNUAL MEETING OF THE ZOOLOGICAL SOCIETY OF JAPAN) :

    Takao Toshifumi, Satomi Yoshinori, Suto Kouzou

    Zoological science　Vol. 21　No. 12　p. 1250-1251　2004

    Publisher: Zoological Society of Japan

  47. Investigation for the role of KaiC phosphorylation in circadian clock system of Synechococcus elongatus PCC7942

    R Kiyohara, T Nishiwaki, C Lee, Y Satomi, H Kageyama, M Nakajima, M Temamoto, H Iwasaki, T Takao, T Kondo

    PLANT AND CELL PHYSIOLOGY　Vol. 45　p. S219-S219　2004　Research paper, summary (international conference)

  48. 2SC04 Regulation of Light Signaling in Rod Cells by G-protein βγ Complex

    Kassai H, Aiba A, Nakao K, Nakamuta K, Katsuki M, Xiong Wei-Hone, Yau Kine-Wai, Imai H, Shichida Y, Takao T, Okano T, Fukada Y

    Seibutsu Butsuri　Vol. 44　No. 0　2004

    Publisher: The Biophysical Society of Japan General Incorporated Association

  49. ゲノミクス・プロテオミクスの新展開

    NTS　2004

  50. Construction of Peptidome Database for Endogenous Peptides in Mouse Brain

    KUWAHARA Hiromiki, TANAKA Junko, KIHARA Takahiro, MATSUBAE Masami, MATSUI Yasuko, TAKAO Toshifumi, ISOYAMA Masaharu, MINAMINO Naoto

    Vol. 2002　p. 427-428　2003/02/01

  51. Proteomics Research by Matrix-Assisted Laser Desorption / Ionization Mass Spectrometry

    TAKAO Toshifumi

    The Review of laser engineering　Vol. 31　No. 1　p. 13-15　2003/01/15

    Publisher: レ-ザ-学会

  52. プロテオミクスにおける質量分析の現状 (〔2002年8月〕第1土曜特集 プロテオミクス研究の新しい展開) -- (解析法の現状)

    高尾 敏文

    医学のあゆみ　Vol. 202　No. 5　p. 291-294　2002/08/03

    Publisher: 医歯薬出版

  53. Peptidome Project : Its Purpose And Methods

    KUWAHARA Hiromiki, TANAKA Junko, KIHARA Takahiro, MATSUBAE Masami, TAKAO Toshifumi, MINAMINO Naoto

    Vol. 2001　p. 369-370　2002/03/01

  54. A Proteomic Analysis of Leaf Sheaths from Rice.

    Shen Shihua, Matsubae Masami, Takao Toshifumi, Tanaka Naoki, Komatsu Setsuko

    J Biochem (Tokyo)　Vol. 132　No. 4　p. 613-620　2002

    Publisher: The Japanese Biochemical Society

  55. Structural Studies by stepwise Enzymatic Degradation of the Main Backbone of Soybean Soluble Polysaccharides Consisting of Galacturonan and Rhamnogalacturonan

    Akihiro NAKAMURA, Hitoshi FURUTA, Hirokazu MAEDA, Toshifumi TAKAO, Yasunori NAGAMATSU

    Biosci. Biotechnol. Biochem.　Vol. 66　No. 6　p. 1301-1313　2002

    Publisher: Japan Society for Bioscience, Biotechnology, and Agrochemistry

  56. Analysis of the Molecular Construction of Xylogalacturonan isolated from soluble Soybean polysaccharides

    Akihiro NAKAMURA, Hitoshi FURUTA, Hirokazu MAEDA, Toshifumi TAKAO, Yasunori NAGAMATSU

    Biosci. Biotechnol. Biochem.　Vol. 66　No. 5　p. 1155-1158　2002

    Publisher: Japan Society for Bioscience, Biotechnology, and Agrochemistry

  57. プロテオーム:分析法 (新世紀における蛋白質科学の進展) -- (第1部 蛋白質研究方法の進展)

    高尾 敏文, 松八重 雅美, 奥村 宣明

    蛋白質核酸酵素　Vol. 46　No. 11　p. 1422,1504-1509　2001/08

    Publisher: 共立出版

  58. A ubiquitin-like system mediates protein lipidation

    Y Ichimura, T Kirisako, T Takao, Y Satomi, Y Shimonishi, N Ishihara, N Mizushima, Tanida, I, E Kominami, M Ohsumi, T Noda, Y Ohsumi

    NATURE　Vol. 408　No. 6811　p. 488-492　2000/11

  59. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

    T Kirisako, Y Ichimura, H Okada, Y Kabeya, N Mizushima, T Yoshimori, M Ohsumi, T Takao, T Noda, Y Ohsumi

    JOURNAL OF CELL BIOLOGY　Vol. 151　No. 2　p. 263-275　2000/10

  60. Automated interpretation of low-energy collision-induced dissociation spectra by SeqMS, a software aid for de novo sequencing by tandem mass spectrometry

    J Fernandez-de-Cossio, J Gonzalez, Y Satomi, T Shima, N Okumura, Besada, V, L Betancourt, G Padron, Y Shimonishi, T Takao

    ELECTROPHORESIS　Vol. 21　No. 9　p. 1694-1699　2000/05

  61. Chemical structure of nuclear proteins which are phosphorylated during meiotic maturation of starfish oocytes

    K Matoba, Y Matsumoto, T Hongo, Y Nagamatsu, H Sugino, T Shimizu, T Takao, Y Shimonishi, S Ikegami

    BIOCHEMISTRY　Vol. 39　No. 21　p. 6390-6400　2000/05

  62. 新実験講座 蛋白質の質量分析(1)磁場型質量分析装置とその応用

    高尾 敏文

    蛋白質核酸酵素　Vol. 45　No. 5　p. 735-740　2000/04

    Publisher: 共立出版

  63. Novel rearranged ions observed for protonated peptides via metastable decomposition in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

    SP Fang, T Takao, Y Satomi, WJ Mo, Y Shimonishi

    JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY　Vol. 11　No. 4　p. 345-351　2000/04

  64. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

    M Kawabuchi, Y Satomi, T Takao, Y Shimonishi, S Nada, K Nagai, A Tarakhovsky, M Okada

    NATURE　Vol. 404　No. 6781　p. 999-1003　2000/04

  65. Activation of Rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin

    M Masuda, L Betancourt, T Matsuzawa, T Kashimoto, T Takao, Y Shimonishi, Y Horiguchi

    EMBO JOURNAL　Vol. 19　No. 4　p. 521-530　2000/02

  66. Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2 : Role of N-terminal hydrophobic portion in its multiple functions(共著)

    J. Immunology　Vol. 166　p. 2610-2616　2000

  67. Differentiating alpha- and beta-aspartic acids by electrospray ionization and low-energy tandem mass spectrometry

    LJ Gonzalez, T Shimizu, Y Satomi, L Betancourt, Besada, V, G Padron, R Orlando, T Shirasawa, Y Shimonishi, T Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 14　No. 22　p. 2092-2102　2000

  68. Sequencing of oxidized methionine-containing peptides for protein identification

    WJ Mo, YL Ma, T Takao, TA Neubert

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 14　No. 21　p. 2080-2081　2000　Rapid communication, short report, research note, etc. (scientific journal)

  69. Keramamides M and N, two new cyclic peptides with a sulfate ester from Theonella sponge

    M Tsuda, H Ishiyama, K Masuko, T Takao, Y Shimonishi, J Kobayashi

    TETRAHEDRON　Vol. 55　No. 43　p. 12543-12548　1999/10

  70. Structural characterization of chemically derivatized oligosaccharides by nanoflow electrospray ionization mass spectrometry

    WJ Mo, H Sakamoto, A Nishikawa, N Kagi, JI Langridge, Y Shimonishi, T Takao

    ANALYTICAL CHEMISTRY　Vol. 71　No. 18　p. 4100-4106　1999/09

  71. 沖縄産海綿Theonella sp.より単離した新規環状ペプチドKeramamide Lの構造

    植本 裕, 津田 正史, 繁森 英幸, 小林 淳一, 高尾 敏文, 下西 康嗣

    日本薬学会年会要旨集　Vol. 119年会　No. 2　p. 128-128　1999/03

    Publisher: (公社)日本薬学会

  72. Chloroplast Cpn20 forms a tetrameric structure in Arabidopsis thaliana

    Y Koumoto, T Shimada, M Kondo, T Takao, Y Shimonishi, Hara-Nishimura, I, M Nishimura

    PLANT JOURNAL　Vol. 17　No. 5　p. 467-477　1999/03

  73. Structural characterization Acetobacter diazotropicus levansucrase by matrix-assisted laser desorption/ionization mass spectrometry: Identification of an N-terminal blocking group and a free-thiol cysteine residue

    L Betancourt, T Takao, L Hernandez, G Padron, Y Shimonishi

    JOURNAL OF MASS SPECTROMETRY　Vol. 34　No. 3　p. 169-174　1999/03

  74. Complementary DNA cloning and characterization of ferredoxin localized in bundle-sheath cells of maize leaves

    T Matsumura, Y Kimata-Ariga, H Sakakibara, T Sugiyama, H Murata, T Takao, Y Shimonishi, T Hase

    PLANT PHYSIOLOGY　Vol. 119　No. 2　p. 481-488　1999/02

  75. A novel endogenous inhibitor of phenoloxidase from Musca domestica has a cystine motif commonly found in snail and spider toxins

    AC Daquinag, T Sato, H Koda, T Takao, M Fukuda, Y Shimonishi, T Tsukamoto

    BIOCHEMISTRY　Vol. 38　No. 7　p. 2179-2188　1999/02

  76. Automated interpretation of high-energy collision-induced dissociation spectra of singly protonated peptides by 'SeqMS', a software aid for de novo sequencing by tandem mass spectrometry (vol 12, pg 1867, 1998)

    J Fernandez-de-Cossio, J Gonzalez, L Betancourt, Besada, V, G Padron, Y Shimonishi, T Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 13　No. 2　p. 138-138　1999　Other

  77. The metastable decomposition of a peptide containing oxidized methionine(s) in matrix-assisted laser desorption ionization time-of-flight mass spectrometry

    L Betancourt, T Takao, J Gonzalez, O Reyes, Besada, V, G Padron, Y Shimonishi

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 13　No. 11　p. 1075-1076　1999　Rapid communication, short report, research note, etc. (scientific journal)

  78. Bordetella dermonecrocitizing toxin is a transglutaminase specific to Rho proteins

    MASUDA Minako, BETANCOURT Lazaro, KASHIMOTO Takashige, TAKAO Toshifumi, SHIMONISHI Yasutsugu, HORIGUCHI Yasuhiko

    Vol. 21　p. 563-563　1998/12/01

  79. Structural analysis of oligosaccharides derivatized with 4-aminobenzoic acid 2-(diethylamino)ethyl ester by matrix-assisted laser desorption/ionization mass spectrometry

    WJ Mo, T Takao, H Sakamoto, Y Shimonishi

    ANALYTICAL CHEMISTRY　Vol. 70　No. 21　p. 4520-4526　1998/11

  80. Specific isoprenyl group linked to transducin gamma-subunit is a determinant of its unique signaling properties among G-proteins

    T Matsuda, Y Hashimoto, H Ueda, T Asano, Y Matsuura, T Doi, T Takao, Y Shimonishi, Y Fukada

    BIOCHEMISTRY　Vol. 37　No. 27　p. 9843-9850　1998/07

  81. Keramamides K and L, new cyclic peptides containing unusual tryptophan residue from Theonella sponge

    H Uemoto, Y Yahiro, H Shigemori, M Tsuda, T Takao, Y Shimonishi, J Kobayashi

    TETRAHEDRON　Vol. 54　No. 24　p. 6719-6724　1998/06

  82. Automated interpretation of high-energy collision-induced dissociation spectra of singly protonated peptides by 'SeqMS', a software aid for De Novo sequencing by tandem mass spectrometry

    J Fernandez-de-Cossio, J Gonzalez, L Betancourt, Besada, V, G Padron, Y Shimonishi, T Takao

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 12　No. 23　p. 1867-1878　1998

  83. A novel modification of the lysine residue at position 12 of histone H4 in starfish sperm

    K Nunomura, T Shimizu, K Hozumi, T Takao, Y Shimonishi, S Ikegami

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY　Vol. 61　No. 12　p. 2151-2152　1997/12

  84. Structure of a covalently cross-linked form of core histones present in the starfish sperm

    T Shimizu, T Takao, K Hozumi, K Nunomura, S Ohta, Y Shimonishi, S Ikegami

    BIOCHEMISTRY　Vol. 36　No. 40　p. 12071-12079　1997/10

  85. The oxidation of selenocysteine is involved in the inactivation of glutathione peroxidase by nitric oxide donor

    M Asahi, J Fujii, T Takao, T Kuzuya, M Hori, Y Shimonishi, N Taniguchi

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 272　No. 31　p. 19152-19157　1997/08

  86. A novel histone heterodimer that appears at a specific stage of embryonic development.

    S Ikegami, T Shimizu, K Hozumi, K Nunomura, T Takao, Y Shimonishi

    FASEB JOURNAL　Vol. 11　No. 9　p. A1109-A1109　1997/07　Research paper, summary (international conference)

  87. Isolation of bioactive compounds from Helix aspersa nerve tissue and the effect of pQPPLPRYamide on heart, esophagus and central neurons of H-aspersa and rectum of Anodonta woodiana

    M Ohtani, Y Muneoka, O Matsushima, T Takao, Y Shimonishi, AR White, S Pedder, R Sharma, MA Lennon, S Katugampola, RJ Walker

    GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM　Vol. 29　No. 1　p. 103-111　1997/07

  88. High-sensitivity mass spectrometry for analysis of posttranslational modifications

    T Takao, T Shimizu, S Ikegami, Y Shimonishi

    JOURNAL OF PROTEIN CHEMISTRY　Vol. 16　No. 5　p. 409-413　1997/07

  89. Spermatozoa and dimer histone of embryo of sea star can be formed in birds’ erythrocyte nucleosome.

    清水孝彦, 穂積啓子, 布村一人, 寺川雄大, 高尾敏文, 下西康嗣, 池上晋

    日本発生生物学会大会発表要旨集　Vol. 30th　1997

  90. The Use of Capillary Liquid Chromatograph/Electrospray Mass Spectrometry to Identify a Specific Cysteine Residue Susceptible to S-Thiolation in Recombinant Human Cu, Zn Superoxide Dismutase

    Res. Commun. Biochem. Cell & Mol. Biol.　Vol. 1　p. 205-217　1997

  91. Accurate peptide sequencing by post-source decay matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

    WJ Mo, T Takao, Y Shimonishi

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 11　No. 17　p. 1829-1834　1997

  92. Arachidonate 12-lipoxygenases - Catalytic properties and regulation of the enzyme gene

    S Yamamoto, K Kishimoto, T Arakawa, H Suzuki, M Nakamura, T Yoshimoto, T Takao, Y Shimonishi, T Tanabe

    EICOSANOIDS AND OTHER BIOACTIVE LIPIDS IN CANCER, INFLAMMATION, AND RADIATION INJURY 3　Vol. 407　p. 191-196　1997

  93. Identification of two palmitoyl groups in octopus rhodopsin

    Masashi Nakagawa, Tatsuo Iwasa, Satoshi Kikkawa, Toshifumi Takao, Yasutsugu Shimonishi, Motoyuki Tsuda

    Photochemistry and Photobiology　Vol. 65　No. 1　p. 187-191　1997

    Publisher: Blackwell Publishing Inc.

  94. Molecular identification and characterization of cytosolic isoforms of glutamine synthetase in maize roots

    H Sakakibara, H Shimizu, T Hase, Y Yamazaki, T Takao, Y Shimonishi, T Sugiyama

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 271　No. 47　p. 29561-29568　1996/11

  95. 核膜孔ターゲティング複合体94kDa構成因子, 低分子量GTP結合蛋白質Ran, 及びRan結合蛋白質RanBP1で構成される3者複合体の機能解析

    今本 尚子, 立花 太郎, 小瀬 真吾, 高尾 敏文, 下西 康嗣, 米田 悦啓

    日本分子生物学会年会プログラム・講演要旨集　Vol. 19　p. 288-288　1996/08/01

  96. ゲラニルゲラニル化トランスデューシンβγの作成と機能解析

    橋本 祐一, 松田 孝彦, 深田 吉孝, 松浦 善治, 土井 知子, 高尾 敏文, 下西 康嗣

    日本分子生物学会年会プログラム・講演要旨集　Vol. 19　p. 322-322　1996/08/01

  97. 一酸化炭素(NO)及びペルオキシ亜硝酸(ONOO)によるグルタチオンペルオキシダーゼ(GPx)の阻害機構

    朝日 通雄, 高尾 敏文, 藤井 順逸, 鈴木 敬一郎, 下西 康嗣, 谷口 直之

    日本分子生物学会年会プログラム・講演要旨集　Vol. 19　p. 497-497　1996/08/01

  98. Identification of the functional region on the superantigen Yersinia pseudotuberculosis-derived mitogen responsible for induction of lymphocyte proliferation by using synthetic peptides

    K Yoshino, T Takao, M Ishibashi, Y Samejima, Y Shimonishi, T Takeda

    FEBS LETTERS　Vol. 390　No. 2　p. 196-198　1996/07

  99. Preparation and characterization of monoclonal antibodies specific for lauroylated isoform of bovine transducin alpha-subunit: Immunohistochemical analysis of bovine retinas

    O Shouno, K Kokame, M Araki, T Takao, Y Shimonishi, M Murata, T Yoshizawa, Y Fukada

    JOURNAL OF NEUROCHEMISTRY　Vol. 66　No. 5　p. 2188-2196　1996/05

  100. イエバエフェノールオキシダーゼインヒビターの分子内ジスルフィド結合架橋様式 : 有機化学・天然物化学

    佐藤 孝, 江田 春樹, 高尾 敏文, 下西 康嗣, 塚本 卓治

    日本農藝化學會誌　Vol. 70　p. 62-62　1996/03/05

    Publisher: 社団法人日本農芸化学会

  101. Suicide inactivation of porcine leukocyte 12-lipoxygenase associated with its incorporation of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid derivative

    K Kishimoto, M Nakamura, H Suzuki, T Yoshimoto, S Yamamoto, T Takao, Y Shimonishi, T Tanabe

    BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM　Vol. 1300　No. 1　p. 56-62　1996/03

  102. A covalently crosslinked histone

    T Shimizu, K Hozumi, S Horiike, K Nunomura, S Ikegami, T Takao, Y Shimonishi

    NATURE　Vol. 380　No. 6569　p. 32-32　1996/03　Rapid communication, short report, research note, etc. (scientific journal)

  103. Effect of the position of a basic amino acid on C-terminal rearrangement of protonated peptides upon collision-induced dissociation

    J Gonzalez, Besada, V, H Garay, O Reyes, G Padron, Y Tambara, T Takao, Y Shimonishi

    JOURNAL OF MASS SPECTROMETRY　Vol. 31　No. 2　p. 150-158　1996/02

  104. Fluctuation in and chemical structure of dimer histone in process of development of embryo.

    清水孝彦, 穂積啓子, 布村一人, 池上晋, 高尾敏文, 下西康嗣

    日本分子生物学会年会プログラム・講演要旨集　Vol. 19th　1996

  105. Sensitive analysis of oligosaccharides derivatized with 4-aminobenzoic acid 2-(diethylamino)ethyl ester by matrix-assisted laser desorption ionization mass spectrometry (vol 10, pg 637, 1996)

    T Takao, Y Tambara, A Nakamura, K Yoshino, H Fukuda, M Fukuda, Y Shimonishi

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 10　No. 9　p. 1163-1163　1996　Other

  106. 質量分析による蛋白質の構造解析

    生化学　Vol. 68　p. 1-13　1996

  107. 磁場型質量分析計を用いた蛋白質のキャピラリーHPLC/ エレクトロスプレーイオン化質量分析

    日本医用マススペクトル学会サーキュラー　No. 36　p. 1-6　1996

  108. Analysis of protein primary structures by mass spectrometry

    T Takao

    SEIKAGAKU　Vol. 68　No. 1　p. 1-13　1996/01　Book review, literature introduction, etc.

  109. Capillary Liquid Chromatography/Electrospray Mass Spectrometry with a Magnetic Sector Instrument for Accurate Mass Measurement of Proteins

    No. 36　p. 1-6　1996

  110. Sensitive analysis of oligosaccharides derivatized with 4-aminobenzoic acid 2-(diethylamino)ethyl ester by matrix-assisted laser desorption/ionization mass spectrometry

    T Takao, Y Tambara, A Nakamura, K Yoshino, H Fukuda, M Fukuda, Y Shimonishi

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 10　No. 6　p. 637-640　1996

  111. USE OF THE DERIVATIZING AGENT 4-AMINOBENZOIC ACID 2-(DIETHYLAMINO)ETHYL ESTER FOR HIGH-SENSITIVITY DETECTION OF OLIGOSACCHARIDES BY ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY

    K YOSHINO, T TAKAO, H MURATA, Y SHIMONISHI

    ANALYTICAL CHEMISTRY　Vol. 67　No. 21　p. 4028-4031　1995/11　Article, review, commentary, editorial, etc. (scientific journal)

  112. Structure and Action of Bioactive Peptides Isolated from the Newt, Cynops pyrrhogaster : I. A. C-type Natriuretic Peptide (CNP)

    TERANISHI Hitoshi, MUNEOKA Yojiro, UESAKA Toshihiro, ANDO Masaaki, CHIBA Chikafumi, SAITO Takehiko, TAKAO Toshifumi, SHIMONISHI Yasutsugu, MINAKATA Hiroyuki, NOMOTO Kyosuke

    Vol. 1995　p. 173-176　1995/10/01

  113. Structure and Action of Bioactive Peptides Isolated from the Newt, Cynops pyrrhogaster : II. Four VIP-Related Peptides and Two Neurotensin-Related Peptides

    TERANISHI Hitoshi, TAKAHASHI Toshio, OHTANI Masahiro, ANDO Masaaki, MUNEOKA Yojiro, CHIBA Chikafumi, SAITO Takehiko, TAKAO Toshifumi, SHIMONISHI Yasutsugu

    Vol. 1995　p. 177-180　1995/10/01

  114. IN-VIVO EVIDENCE FOR INVOLVEMENT OF A 58 KDA COMPONENT OF NUCLEAR PORE-TARGETING COMPLEX IN NUCLEAR-PROTEIN IMPORT

    N IMAMOTO, T SHIMAMOTO, T TAKAO, T TACHIBANA, S KOSE, M MATSUBAE, T SEKIMOTO, Y SHIMONISHI, Y YONEDA

    EMBO JOURNAL　Vol. 14　No. 15　p. 3617-3626　1995/08

  115. THE NUCLEAR PORE-TARGETING COMPLEX BINDS TO NUCLEAR-PORES AFTER ASSOCIATION WITH A KARYOPHILE

    N IMAMOTO, T SHIMAMOTO, S KOSE, T TAKAO, T TACHIBANA, M MATSUBAE, T SEKIMOTO, Y SHIMONISHI, Y YONEDA

    FEBS LETTERS　Vol. 368　No. 3　p. 415-419　1995/07

  116. ROLE OF HETEROGENEOUS N-TERMINAL ACYLATION OF RECOVERIN IN RHODOPSIN PHOSPHORYLATION

    K SANADA, K KOKAME, T YOSHIZAWA, T TAKAO, Y SHIMONISHI, Y FUKADA

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 270　No. 26　p. 15459-15462　1995/06　Article, review, commentary, editorial, etc. (scientific journal)

  117. O-GLYCOSYLATION OF THE THR70 RESIDUE OF CELL-ADHESIVE LYSOZYME IN YEAST

    T YAMADA, A UYEDA, T TAKAO, Y SHIMONISHI, M MATSUSHIMA, M KIKUCHI

    EUROPEAN JOURNAL OF BIOCHEMISTRY　Vol. 230　No. 3　p. 965-970　1995/06

  118. CHARACTERIZATION OF A HIGHLY TOXIC, LARGE MOLECULAR-SIZE HEAT-STABLE ENTEROTOXIN PRODUCED BY A CLINICAL ISOLATE OF YERSINIA-ENTEROCOLITICA

    K YOSHINO, T TAKAO, XZ HUANG, H MURATA, H NAKAO, T TAKEDA, Y SHIMONISHI

    FEBS LETTERS　Vol. 362　No. 3　p. 319-322　1995/04

  119. PRIMARY STRUCTURE OF A POTENT ENDOGENOUS DOPA-CONTAINING INHIBITOR OF PHENOL OXIDASE FROM MUSCA-DOMESTICA

    AC DAQUINAG, S NAKAMURA, T TAKAO, Y SHIMONISHI, T TSUKAMOTO

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 92　No. 7　p. 2964-2968　1995/03

  120. KERAMAMIDE-E, KERAMAMIDE-G, KERAMAMIDE-H AND KERAMAMIDE-J, NEW CYCLIC-PEPTIDES CONTAINING AN OXAZOLE OR A THIAZOLE RING FROM A THEONELLA SPONGE

    J KOBAYASHI, F ITAGAKI, H SHIGEMORI, T TAKAO, Y SHIMONISHI

    TETRAHEDRON　Vol. 51　No. 9　p. 2525-2532　1995/02

  121. PURIFICATION AND CHARACTERIZATION OF A NOVEL SUPERANTIGEN PRODUCED BY A CLINICAL ISOLATE OF YERSINIA-PSEUDOTUBERCULOSIS

    K YOSHINO, J ABE, H MURATA, T TAKAO, T KOHSAKA, Y SHIMONISHI, T TAKEDA

    FEBS LETTERS　Vol. 356　No. 1　p. 141-144　1994/12

  122. POSITIVE-ION FAST-ATOM-BOMBARDMENT TANDEM MASS-SPECTROMETRY OF PEPTIDE NUCLEIC-ACIDS

    T TAKAO, H FUKUDA, J COULL, Y SHIMONISHI

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 8　No. 12　p. 925-928　1994/12

  123. CHARACTERIZATION OF INTERACTIONS BETWEEN TRANSDUCIN ALPHA/BETA-GAMMA-SUBUNITS AND LIPID-MEMBRANES

    T MATSUDA, T TAKAO, Y SHIMONISHI, M MURATA, T ASANO, T YOSHIZAWA, Y FUKADA

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 269　No. 48　p. 30358-30363　1994/12

  124. ACTIVATION PEPTIDE OF HUMAN FACTOR-IX HAS OLIGOSACCHARIDES O-GLYCOSIDICALLY LINKED TO THREONINE RESIDUES AT 159 AND 169

    KL AGARWALA, S KAWABATA, T TAKAO, H MURATA, Y SHIMONISHI, H NISHIMURA, S IWANAGA

    BIOCHEMISTRY　Vol. 33　No. 17　p. 5167-5171　1994/05

  125. VASOACTIVE-INTESTINAL-PEPTIDE INDUCES DIFFERENTIATION AND MAP KINASE ACTIVATION IN PC12H CELLS

    N OKUMURA, Y MIYATAKE, T TAKAO, T TAMARU, K NAGAI, M OKADA, H NAKAGAWA

    JOURNAL OF BIOCHEMISTRY　Vol. 115　No. 2　p. 304-308　1994/02

  126. OPTIMIZATION OF SKIMMER VOLTAGES OF AN ELECTROSPRAY ION-SOURCE COUPLED WITH A MAGNETIC-SECTOR INSTRUMENT

    H MURATA, T TAKAO, Y SHIMONISHI

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 8　No. 2　p. 205-210　1994/02

  127. EFFECTS OF CARBOXYL METHYLATION OF PHOTORECEPTOR G-PROTEIN GAMMA-SUBUNIT IN VISUAL TRANSDUCTION

    Y FUKADA, T MATSUDA, K KOKAME, T TAKAO, Y SHIMONISHI, T AKINO, T YOSHIZAWA

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 269　No. 7　p. 5163-5170　1994/02

  128. A NEW LIPOPEPTIDE BIOSURFACTANT PRODUCED BY ARTHROBACTER SP STRAIN MIS38

    M MORIKAWA, H DAIDO, T TAKAO, S MURATA, Y SHIMONISHI, T IMANAKA

    JOURNAL OF BACTERIOLOGY　Vol. 175　No. 20　p. 6459-6466　1993/10

  129. AUTOMATIC PRECURSOR-ION SWITCHING IN A 4-SECTOR TANDEM MASS-SPECTROMETER AND ITS APPLICATION TO ACQUISITION OF THE MS/MS PRODUCT IONS DERIVED FROM A PARTIALLY O-18-LABELED PEPTIDE FOR THEIR FACILE ASSIGNMENTS

    T TAKAO, J GONZALEZ, K YOSHIDOME, K SATO, T ASADA, Y KAMMEI, Y SHIMONISHI

    ANALYTICAL CHEMISTRY　Vol. 65　No. 17　p. 2394-2399　1993/09

  130. PURIFICATION AND SEQUENCE DETERMINATION OF HEAT-STABLE ENTEROTOXIN ELABORATED BY A CHOLERA TOXIN-PRODUCING STRAIN OF VIBRIO-CHOLERAE O1

    K YOSHINO, M MIYACHI, T TAKAO, PK BAG, H XIAOZHE, GB NAIR, T TAKEDA, Y SHIMONISHI

    FEBS LETTERS　Vol. 326　No. 1-3　p. 83-86　1993/07

  131. PRIMARY STRUCTURE OF MICROBIAL TRANSGLUTAMINASE FROM STREPTOVERTICILLIUM SP STRAIN-S-8112

    T KANAJI, H OZAKI, T TAKAO, H KAWAJIRI, H IDE, M MOTOKI, Y SHIMONISHI

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 268　No. 16　p. 11565-11572　1993/06

  132. ONLINE MEMBRANE BLOTTING OF PEPTIDES AND PROTEINS FROM A CAPILLARY COLUMN

    H MURATA, T TAKAO, S ANAHARA, Y SHIMONISHI

    ANALYTICAL BIOCHEMISTRY　Vol. 210　No. 1　p. 206-208　1993/04　Article, review, commentary, editorial, etc. (scientific journal)

  133. ASSEMBLY REGULATORY DOMAIN OF GLIAL FIBRILLARY ACIDIC PROTEIN - A SINGLE PHOSPHORYLATION DIMINISHES ITS ASSEMBLY-ACCELERATING PROPERTY

    Y NAKAMURA, M TAKEDA, S AIMOTO, H HOJO, T TAKAO, Y SHIMONISHI, S HARIGUCHI, T NISHIMURA

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 267　No. 32　p. 23269-23274　1992/11

  134. LIPID MODIFICATION AT THE N-TERMINUS OF PHOTORECEPTOR G-PROTEIN ALPHA-SUBUNIT

    K KOKAME, Y FUKADA, T YOSHIZAWA, T TAKAO, Y SHIMONISHI

    NATURE　Vol. 359　No. 6397　p. 749-752　1992/10

  135. HUMAN FACTOR-IX HAS A TETRASACCHARIDE O-GLYCOSIDICALLY LINKED TO SERINE-61 THROUGH THE FUCOSE RESIDUE

    H NISHIMURA, T TAKAO, S HASE, Y SHIMONISHI, S IWANAGA

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 267　No. 25　p. 17520-17525　1992/09

  136. A method for determination of N-glycosylation sites in glycoproteins by collision-induced dissociation analysis in fast atom bombardment mass spectrometry: Identification of the positions of carbohydrate-linked asparagine in recombinant α-amylase by treatment with peptide-N-glycosidase F in 18O-labeled water

    Javier Gonzalez, Toshifumi Takao, Hideaki Hori, Vladimir Besada, Rolando Rodriguez, Gabriel Padron, Yasutsugu Shimonishi

    Analytical Biochemistry　Vol. 205　No. 1　p. 151-158　1992/08/15

  137. Analysis of the primary structures of proteins by mass spectrometry

    Y. Shimonishi, T. Takao, H. Hori

    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 37　No. 3　p. 627-640　1992　Book review, literature introduction, etc.

  138. Application of fast atom bombardment mass spectrometry to analysis of protein primary structures.

    TAKAO Toshifumi, SHIMONISHI Yasutsugu

    Seibutsu Butsuri　Vol. 32　No. 179　p. 41-45　1992

    Publisher: The Biophysical Society of Japan General Incorporated Association

  139. Application of Fast Atom Bombardment Mass Spectrometry to Analysis of Protein Primary Structures

    Biophysics　Vol. 32　No. 179　1992

  140. CARBOXYL METHYLATION AND FARNESYLATION OF TRANSDUCIN GAMMA-SUBUNIT SYNERGISTICALLY ENHANCE ITS COUPLING WITH METARHODOPSIN-II

    H OHGURO, Y FUKADA, T TAKAO, Y SHIMONISHI, T YOSHIZAWA, T AKINO

    EMBO JOURNAL　Vol. 10　No. 12　p. 3669-3674　1991/12

  141. FACILE ASSIGNMENT OF SEQUENCE IONS OF A PEPTIDE LABELED WITH O-18 AT THE CARBOXYL TERMINUS

    T TAKAO, H HORI, K OKAMOTO, A HARADA, M KAMACHI, Y SHIMONISHI

    RAPID COMMUNICATIONS IN MASS SPECTROMETRY　Vol. 5　No. 7　p. 312-315　1991/07

  142. IDENTIFICATION OF A NOVEL AMINO-ACID, ORTHO-BROMO-L-PHENYLALANINE, IN EGG-ASSOCIATED PEPTIDES THAT ACTIVATE SPERMATOZOA

    K YOSHINO, T TAKAO, M SUHARA, T KITAI, H HORI, K NOMURA, M YAMAGUCHI, Y SHIMONISHI, N SUZUKI

    BIOCHEMISTRY　Vol. 30　No. 25　p. 6203-6209　1991/06

  143. ANALYSIS OF POSTTRANSLATIONAL MODIFICATIONS OF PROTEINS BY ACCURATE MASS MEASUREMENT IN FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY

    T TAKAO, K YOSHINO, N SUZUKI, Y SHIMONISHI

    BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY　Vol. 19　No. 11　p. 705-712　1990/11

  144. FARNESYLATED GAMMA-SUBUNIT OF PHOTORECEPTOR G-PROTEIN INDISPENSABLE FOR GTP-BINDING

    Y FUKADA, T TAKAO, H OHGURO, T YOSHIZAWA, T AKINO, Y SHIMONISHI

    NATURE　Vol. 346　No. 6285　p. 658-660　1990/08

  145. IDENTIFICATION OF A DISACCHARIDE (XYL-GLC) AND A TRISACCHARIDE (XYL2-GLC) O-GLYCOSIDICALLY LINKED TO A SERINE RESIDUE IN THE 1ST EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HUMAN FACTOR-VII AND FACTOR-IX AND PROTEIN-Z AND BOVINE PROTEIN-Z

    H NISHIMURA, S KAWABATA, W KISIEL, S HASE, T IKENAKA, T TAKAO, Y SHIMONISHI, S IWANAGA

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 264　No. 34　p. 20320-20325　1989/12

  146. A NEW SUGAR CHAIN LINKED TO A SERINE RESIDUE IN THE 1ST EGF-LIKE DOMAIN OF HUMAN AND BOVINE CLOTTING FACTOR-VII, FACTOR-IX AND PROTEIN-Z

    H NISHIMURA, S KAWABATA, S HASE, T IKENAKA, T TAKAO, Y SHIMONISHI, W KISIEL, S IWANAGA

    THROMBOSIS AND HAEMOSTASIS　Vol. 62　No. 1　p. 17-17　1989/08　Research paper, summary (international conference)

  147. A NEW TRISACCHARIDE SUGAR CHAIN LINKED TO A SERINE RESIDUE IN BOVINE BLOOD-COAGULATION FACTOR-VII AND FACTOR-IX

    S HASE, S KAWABATA, H NISHIMURA, H TAKEYA, T SUEYOSHI, T MIYATA, S IWANAGA, T TAKAO, Y SHIMONISHI, T IKENAKA

    JOURNAL OF BIOCHEMISTRY　Vol. 104　No. 6　p. 867-868　1988/12　Article, review, commentary, editorial, etc. (scientific journal)

  148. TACHYPLESIN, A CLASS OF ANTIMICROBIAL PEPTIDE FROM THE HEMOCYTES OF THE HORSESHOE-CRAB (TACHYPLEUS-TRIDENTATUS) - ISOLATION AND CHEMICAL-STRUCTURE

    T NAKAMURA, H FURUNAKA, T MIYATA, F TOKUNAGA, T MUTA, S IWANAGA, M NIWA, T TAKAO, Y SHIMONISHI

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 263　No. 32　p. 16709-16713　1988/11　Article, review, commentary, editorial, etc. (scientific journal)

  149. 質量分析によるタンパク質の一次構造解析

    化学と工業　Vol. 41　1988

  150. Analysis of Protein Primary Structure by Mass Spectrometry

    Chemistry and Chemical Industry　Vol. 41　1988

  151. CHEMICAL CHARACTERIZATION OF RECOMBINANT HUMAN-LEUKOCYTE INTERFERON-A USING FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY

    T TAKAO, M KOBAYASHI, O NISHIMURA, Y SHIMONISHI

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 262　No. 8　p. 3541-3547　1987/03

  152. Studies on Peptides. CXXXVI. : Solution-Phase Synthesis of a 37-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Human Calcitonin Gene-Related Peptide (hCGRP)

    FUJII NOBUTAKA, OTAKA AKIRA, FUNAKOSHI SUSUMU, NOMIZU MOTOYOSHI, AKAJI KENICHI, YAJIMA HARUAKI, YAMAMOTO ITSUO, TORIZUKA KANJI, KITAGAWA KOUKI, AKITA TADASHI, ANDO KENSHI, KAWAMOTO TATSUHIKO, SHIMONISHI YASUTSUGU, TAKAO TOSHIFUMI

    Chemical & pharmaceutical bulletin　Vol. 34　No. 2　p. 613-620　1986/02/25

    Publisher: The Pharmaceutical Society of Japan

  153. Subtilosin A, a new antibiotic peptide produced by Bacillus subtilis 168: Isolation, structural analysis, and biogenesis.

    BABASAKI Katsuhiko, TAKAO Toshifumi, SHIMONISHI Yasutsugu, KURAHASHI Kiyoshi

    J Biochem (Tokyo)　Vol. 98　No. 3　p. 585-603　1985

    Publisher: The Japanese Biochemical Society

  154. VERIFICATION BY MASS-SPECTROMETRY OF THE PRIMARY STRUCTURE OF HUMAN INTERLEUKIN-2

    K FUKUHARA, T TSUJI, K TOI, T TAKAO, Y SHIMONISHI

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 260　No. 19　p. 487-494　1985

  155. VERIFICATION OF PROTEIN-SEQUENCE BY FAST ATOM BOMBARDMENT MASS-SPECTROMETRY - AMINO-ACID-SEQUENCE OF PROTEIN-S, A DEVELOPMENT-SPECIFIC PROTEIN OF MYXOCOCCUS-XANTHUS

    T TAKAO, T HITOUJI, Y SHIMONISHI, T TANABE, S INOUYE, M INOUYE

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 259　No. 10　p. 6105-6109　1984

Publications 15

  1. 蛋白質・核酸・酵素"蛋白質の質量分析(1)磁場型質量分析装置とその応用"

    共立出版　2000

  2. プロテオーム解析法(実験医学別冊)"De novo sequencingのための解析ソフトウェア"

    羊土社　2000

  3. Mass spectrometry of a protein(1) : Magnetic sector mass spectrometer and its application

    2000

  4. Software aid for de novo sequencing

    2000

  5. 質量分析計による分子量の精密測定。

    秀潤社　1998

  6. Accurate measurement of molecular weight by mass spectrometer

    1998

  7. Accurate Peptide Sequencing by Mass Spectrometry.(共著)

    Kluwer Academic Publishers　1998

  8. バイオロジカルマススペクトロメトリー(現代化学・増刊31) "修飾タンパク質"

    東京化学同人　1997

  9. Mass Spectrometric Analysis of Post-Translational Modification of a Protein(共著)

    1997

  10. Capillary Liquied Chromatography/Electrospray Mass Spectrometry with a Magnetic Sector Instrument for Accurate Mass Measurement of Peptide and Protein Mixtures(共著)

    Humana　1995

  11. Determination of Posttranslational Modifications by Mass Spectrometry in Methods in Protein Sequence Analysis. (共著)

    Plenum　1993

  12. Analysis of Post-translational Modifications of Proteins by Mass Spectrometry in The Post-Translational Modifications of Proteins. (共著)

    Japan Scientific Societies Press and CRC Press　1992

  13. 新生化学実験講座タンパク質II(一次構造)"質量分析による構造決定"

    東京化学同人　1990

  14. Methods for Determination of Protein Sequences by Fast Atom Bombardment Mass Spectrometry in Laboratory Methodology in Biochemistry

    CRC Press　1990

  15. Determination of Protein Primary Structure by Mass Spectrometry

    1990

Presentations 1

  1. Active ternary complex of ribonuclease HI: RNA/DNA hybrid: metal ions probed by ESI mass

    2022/09/29

Works 5

  1. 植物細胞エネルギー・代謝ネットワークを制御する分子マシナリー

    2004 -

  2. 質量分析法によるイネ組織・時期特異的超微量タンパク質の解析及び翻訳後修飾情報(糖タンパク質)の構造解析

    2000 -

  3. Proteomic analysis of rice proteins and their post-translational modifications(such as glycosylation)in different tissues or under different conditions by mass spectrometry

    2000 -

  4. 質量分析法による生体内ペプチドの超微量構造解析に関する研究

    1999 -

  5. Research on structural analysis of biological peptides by mass spectrometry

    1999 -