Respiratory tract barrier dysfunction in viral-bacterial co-infection cases

Tomoko Sumitomo, Shigetada Kawabata

Japanese Dental Science Review　Vol. 60　p. 44-52　2024/12　Research paper (scientific journal)

Streptococcus pneumoniaeのモジュロン同定とRNA-seq解析への応用

広瀬 雄二郎, 池田 恵莉, 大野 誠之, 山口 雅也, 川端 重忠

Journal of Oral Biosciences Supplement　Vol. 2024　p. [P3-02]　2024/11

Pneumolysin contributes to dysfunction of nasal epithelial barrier for promotion of pneumococcal dissemination into brain tissue

Yuki Takahara, Tomoko Sumitomo, Masamitsu Kono, Moe Takemura, Yukako Akamatsu, Yujiro Hirose, Masaya Yamaguchi, Masanobu Nakata, Muneki Hotomi, Shigetada Kawabata

mSphere　2024/09/30　Research paper (scientific journal)

Aldehyde metabolism ensures mucociliary clearance in oxidative airway injury

Noriko Shinjyo, Haruna Kimura, Tomomi Yoshihara, Jun Suzuki, Masaya Yamaguchi, Shigetada Kawabata, Yasutaka Okabe

2024/09/12

A genome-scale metabolic model of a globally disseminated hyperinvasive M1 strain of Streptococcus pyogenes.

Yujiro Hirose, Daniel C Zielinski, Saugat Poudel, Kevin Rychel, Jonathon L Baker, Yoshihiro Toya, Masaya Yamaguchi, Almut Heinken, Ines Thiele, Shigetada Kawabata, Bernhard O Palsson, Victor Nizet

mSystems　2024/08/19　Research paper (scientific journal)

Identifying Genetic Variations inemm89Streptococcus pyogenesLinked to Severe Invasive Infections

Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, Hitoshi Otsuka, Noriko Nakanishi, Yu Kazawa, Chikara Nakagawa, Ryo Yamaguchi, Hiroo Sakai, Yuko Matsumoto, Tadayoshi Ikebe, Shigetada Kawabata

2024/07/02

Structural analysis of inactive hyaluronidase of Streptococcus pyogenes(タイトル和訳中)

山口 雅也, 東 孝太郎, 武部 克希, 中田 匡宣, 住友 倫子, 川端 重忠

日本細菌学雑誌　Vol. 79　No. 2　p. 268-268　2024/07

Hybrid sequence-based analysis reveals the distribution of bacterial species and genes in the oral microbiome at a high resolution.

Masaya Yamaguchi, Toshihiro Uchihashi, Shigetada Kawabata

Biochemistry and biophysics reports　Vol. 38　p. 101717-101717　2024/07　Research paper (scientific journal)

腸内細菌叢がマウスのデキストラン硫酸ナトリウム誘発性大腸炎の重症度を制御する(Gut microbiota controls the severity of dextran sulfate sodium-induced colitis in mice)

池田 恵莉, 山口 雅也, 川端 重忠

日本細菌学雑誌　Vol. 79　No. 2　p. 84-84　2024/06

トランスクリプトーム解析データを基にした肺炎球菌のモジュロンの同定

広瀬 雄二郎, 田渕 敏生, 池田 恵莉, 大野 誠之, 山口 雅也, 川端 重忠

日本細菌学雑誌　Vol. 79　No. 2　p. 141-141　2024/06

Two-component regulatory system TCS08 of a serotype 4 strain in pneumococcal pneumonia pathogenesis

Dalia Talat, Tomoko Sumitomo, Mariko Honda-Ogawa, Yuki Takahara, Yasushi Mori, Masaya Yamaguchi, Masanobu Nakata, Madiha S. Ibrahim, Shigetada Kawabata

Journal of Oral Biosciences　2024/06　Research paper (scientific journal)

Characteristic craniofacial defects associated with a novel USP9X truncation mutation.

Namiki Nagata, Hiroshi Kurosaka, Kotaro Higashi, Masaya Yamaguchi, Sayuri Yamamoto, Toshihiro Inubushi, Miho Nagata, Yasuki Ishihara, Ayumi Yonei, Yohei Miyashita, Yoshihiro Asano, Norio Sakai, Yasushi Sakata, Shigetada Kawabata, Takashi Yamashiro

Human genome variation　Vol. 11　No. 1　p. 21-21　2024/05/16　Research paper (scientific journal)

A genome-wide association study of emm89 Streptococcus pyogenes identifies genetic variations contributing to severe invasive infections

Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, Hitoshi Otsuka, Noriko Nakanishi, Yu Kazawa, Chikara Nakagawa, Ryo Yamaguchi, Hiroo Sakai, Yuko Matsumoto, Tadayoshi Ikebe, Shigetada Kawabata

2024/03/18

Gut microbiota-mediated alleviation of dextran sulfate sodium-induced colitis in mice.

Eri Ikeda, Masaya Yamaguchi, Shigetada Kawabata

Gastro Hep Advances　2024/02　Research paper (scientific journal)

Streptococcus sanguinisが産生する線毛タンパク質のX線結晶構造解析

武部 克希, 鈴木 守, 東 孝太郎, 山口 雅也, 住友 倫子, 川端 重忠, 中田 匡宣

Journal of Oral Biosciences Supplement　Vol. 2023　p. [P1-25]　2023/09

Elucidation of independently modulated genes in Streptococcus pyogenes reveals carbon sources that control its expression of hemolytic toxins

Yujiro Hirose, Saugat Poudel, Anand V. Sastry, Kevin Rychel, Cameron R. Lamoureux, Richard Szubin, Daniel C. Zielinski, Hyun Gyu Lim, Nitasha D. Menon, Helena Bergsten, Satoshi Uchiyama, Tomoki Hanada, Shigetada Kawabata, Bernhard O. Palsson, Victor Nizet

mSystems　2023/06/06　Research paper (scientific journal)

Involvement of ribonuclease Y in pilus production by M49 Streptococcus pyogenes strain via modulation of messenger RNA level of transcriptional regulator.

Seiko Kubota, Masanobu Nakata, Yujiro Hirose, Masaya Yamaguchi, Bernd Kreikemeyer, Narikazu Uzawa, Tomoko Sumitomo, Shigetada Kawabata

Microbiology and immunology　Vol. 67　No. 7　p. 319-333　2023/05/03　Research paper (scientific journal)

Construction of Human Three-Dimensional Lung Model Using Layer-by-Layer Method

Yukako Akamatsu, Takami Akagi, Tomoko Sumitomo, Yuki Takahara, Shigehisa Akiyama, Shigetada Kawabata, Mitsuru Akashi

Tissue Engineering Part C: Methods　Vol. 29　No. 3　p. 95-102　2023/03/01　Research paper (scientific journal)

肺炎球菌の自己融解酵素LytAによる溶菌過程の高速AFM観察(High-speed AFM observation of the lysis process of bacterial cell by pneumococcal autolysin LytA)

太田 悠夢, 山下 隼人, 東 孝太郎, 山口 雅也, 川端 重忠, 阿部 真之

日本細菌学雑誌　Vol. 78　No. 1　p. 78-78　2023/02

侵襲性に関与するemm89型化膿レンサ球菌の因子の探索と分子生物学的解析

大野 誠之, 山口 雅也, 元岡 大祐, 広瀬 雄二郎, 東 孝太郎, 秋山 徹, 住友 倫子, 池辺 忠義, 奥野 ルミ, 川端 重忠

日本細菌学雑誌　Vol. 78　No. 1　p. 128-128　2023/02

Analysis of FctB3 crystal structure and insight into its structural stabilization and pilin linkage mechanisms.

2023　Research paper (scientific journal)

基礎研究から見た化膿レンサ球菌による病態形成機構と宿主の防御機構

山口雅也, 川端重忠

医学のあゆみ　Vol. in press　2023　Research paper (scientific journal)

Biological Evaluation of the Effect of Root Canal Sealers Using a Rat Model

Motoki Okamoto, Sayako Matsumoto, Kiichi Moriyama, Hailing Huang, Masakatsu Watanabe, Jiro Miura, Keita Sugiyama, Yujiro Hirose, Manabu Mizuhira, Nanako Kuriki, Julian G. Leprince, Yusuke Takahashi, Shigetada Kawabata, Mikako Hayashi

Pharmaceutics　Vol. 14　No. 10　p. 2038-2038　2022/09/24　Research paper (scientific journal)

Oral mitis group streptococci: a silent majority in our oral cavity

Nobuo Okahashi, Masanobu Nakata, Hirotaka Kuwata, Shigetada Kawabata

Microbiology and Immunology　Vol. 66　No. 12　p. 539-551　2022/09/16　Research paper (scientific journal)

The Group A Streptococcus Interleukin-8 Protease SpyCEP Promotes Bacterial Intracellular Survival by Evasion of Autophagy

René Bergmann, Giuseppe Gulotta, Federica Andreoni, Tomoko Sumitomo, Shigetada Kawabata, Annelies S. Zinkernagel, Gursharan S. Chhatwal, Victor Nizet, Manfred Rohde, Satoshi Uchiyama

Infectious Microbes and Diseases　Vol. 4　No. 3　p. 116-123　2022/09　Research paper (scientific journal)

Contribution of Streptococcus pyogenes M87 protein to innate immune resistance and virulence.

Yujiro Hirose, Piotr Kolesinski, Masanobu Hiraoka, Satoshi Uchiyama, Raymond H Zurich, Monika Kumaraswamy, Elisabet Bjanes, Partho Ghosh, Shigetada Kawabata, Victor Nizet

Microbial pathogenesis　Vol. 169　p. 105636-105636　2022/06/17　Research paper (scientific journal)

肺炎球菌の種の壁を超える進化機構 肺炎球菌は口腔レンサ球菌の遺伝子を取り込んで耐性化する

山口 雅也, 川端重忠

日本歯科医師会雑誌　Vol. 75　No. 3　p. 185-193　2022/06　Research paper (other academic)

Secondary streptococcal infection following influenza

Nobuo Okahashi, Tomoko Sumitomo, Masanobu Nakata, Shigetada Kawabata

Microbiology and Immunology　Vol. 66　No. 6　p. 253-263　2022/06　Research paper (scientific journal)

インフルエンザに合併する細菌性肺炎の重要性

住友 倫子, 川端, 重忠

歯界月報　No. 848　p. 30-35　2022/03

Oral mitis group streptococci reduce infectivity of influenza A virus via acidification and H2O2 production.

Nobuo Okahashi, Tomoko Sumitomo, Masanobu Nakata, Hirotaka Kuwata, Shigetada Kawabata

PloS one　Vol. 17　No. 11　2022　Research paper (scientific journal)

Pneumococcal BgaA Promotes Host Organ Bleeding and Coagulation in a Mouse Sepsis Model.

Moe Takemura, Masaya Yamaguchi, Momoko Kobayashi, Tomoko Sumitomo, Yujiro Hirose, Daisuke Okuzaki, Masayuki Ono, Daisuke Motooka, Kana Goto, Masanobu Nakata, Narikazu Uzawa, Shigetada Kawabata

Frontiers in cellular and infection microbiology　Vol. 12　p. 844000-844000　2022　Research paper (scientific journal)

Unique virulence role of post-translocational chaperone PrsA in shaping Streptococcus pyogenes secretome

Zhao-Yi Wu, Anaamika Campeau, Chao-Hsien Liu, David J. Gonzalez, Masaya Yamaguchi, Shigetada Kawabata, Chieh-Hsien Lu, Chian-Yu Lai, Hao-Chieh Chiu, Yung-Chi Chang

Virulence　Vol. 12　No. 1　p. 2633-2647　2021/12　Research paper (scientific journal)

化膿レンサ球菌の不活性型ヒアルロン酸分解酵素の結晶構造解析と活性型変異体の構造予測(Structural analysis of Streptococcus pyogenes hyaluronidase and in silico analysis based on structural models)

東 孝太郎, 山口 雅也, 中田 匡宣, 武部 克希, 住友 倫子, 鈴木 守, 川端 重忠

Journal of Oral Biosciences Supplement　Vol. 2021　p. 181-181　2021/10

GP96 drives exacerbation of secondary bacterial pneumonia following influenza A virus infection

Sumitomo T, Nakata M, Nagase S, Takahara Y, Honda-Ogawa M, Mori Y, Akamatsu Y, Yamaguchi M, Okamoto S, Kawabata S

mBIO　Vol. 12　No. 3　2021/06　Research paper (scientific journal)

Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface.

Yujiro Hirose, Masaya Yamaguchi, Tomoko Sumitomo, Masanobu Nakata, Tomoki Hanada, Daisuke Okuzaki, Daisuke Motooka, Yasushi Mori, Hiroshi Kawasaki, Alison Coady, Satoshi Uchiyama, Masanobu Hiraoka, Raymond H Zurich, Masayuki Amagai, Victor Nizet, Shigetada Kawabata

Cell reports　Vol. 34　No. 13　p. 108924-108924　2021/03　Research paper (scientific journal)

微生物の分子論(遺伝子・タンパク質・情報伝達・代謝・各種オミクス等) 結晶構造解析に基づく化膿レンサ球菌におけるヒアルロン酸分解酵素の分子機構解明

東 孝太郎, 山口 雅也, 中田 匡宣, 武部 克希, 住友 倫子, 鈴木 守, 川端 重忠

日本細菌学雑誌　Vol. 76　No. 1　p. 53-53　2021/02

病原因子と生態防御(感染モデル・寄生・免疫・ワクチン)/病原体と感染症 emm 89型化膿レンサ球菌による侵襲性感染症の発症因子の遺伝統計学的探索

大野 誠之, 山口 雅也, 広瀬 雄二郎, 東 孝太郎, 竹本 訓彦, 秋山 徹, 住友 倫子, 池辺 忠義, 川端 重忠

日本細菌学雑誌　Vol. 76　No. 1　p. 59-59　2021/02

ミャンマーで分離された肺炎球菌のシーケンス情報を用いた遺伝子プロファイリングとパンゲノム解析

山口 雅也, Hpoo Pwint Myo Win, 大野 誠之, 東 孝太郎, 広瀬 雄二郎, Mya Mya Aye, Moh Moh Htun, Hlaing Myat Thu, 川端 重忠

日本細菌学雑誌　Vol. 76　No. 1　p. 91-91　2021/02

Respiratory FimA-specific secretory IgA antibodies upregulated by DC-targeting nasal double DNA adjuvant are essential for elimination of Porphyromonas gingivalis.

Kataoka K, Kawabata S, Koyanagi K, Hashimoto Y, Miyake T, Fujihashi K

Frontiers in Immunology　Vol. 12　p. 634923-634923　2021/02　Research paper (scientific journal)

Epidemiological Analysis of Pneumococcal Strains Isolated at Yangon Children's Hospital in Myanmar via Whole-genome Sequencing-based Methods.

Yamaguchi M, Myo Win H. P, Higashi K, Ono M, Hirose Y, Motooka D, Okuzaki D, Aye M. M, Htun M. M, Thu H. M, Kawabata S

Microbial Genomics　Vol. 7　No. 2　2021/02　Research paper (scientific journal)

Role of BgaA as a pneumococcal virulence factor elucidated by molecular evolutionary analysis.

Masaya Yamaguchi, Moe Takemura, Kotaro Higashi, Kana Goto, Yujiro Hirose, Tomoko Sumitomo, Masanobu Nakata, Narikazu Uzawa, Shigetada Kawabata

Frontiers in Microbiology　Vol. 11　2020/09/24　Research paper (scientific journal)

Detection of Fibronectin-Binding Proteins of Streptococcus pyogenes Using Ligand Blot Analysis

Masanobu Nakata, Shigetada Kawabata

Methods in Molecular Biology　p. 181-190　2020/05/20　Part of collection (book)

Evaluation of decontamination methods of oral biofilms formed on screw-shaped, rough and machined surface implants: an ex vivo study.

Motohiro Otsuki, Masahiro Wada, Masaya Yamaguchi, Shigetada Kawabata, Yoshinobu Maeda, Kazunori Ikebe

International journal of implant dentistry　Vol. 6　No. 1　p. 18-18　2020/04/22　Research paper (scientific journal)

Streptococcal H2O2 inhibits IgE-triggered degranulation of RBL-2H3 mast cell/basophil cell line by inducing cell death

Nobuo Okahashi, Masanobu Nakata, Yujiro Hirose, Hirobumi Morisaki, Hideo Kataoka, Hirotaka Kuwata, Shigetada Kawabata

PLOS ONE　Vol. 15　No. 4　p. e0231101-e0231101　2020/04/17　Research paper (scientific journal)

Performance of a biodegradable composite with hydroxyapatite as a scaffold in pulp tissue repair

Motoki Okamoto, Sayako Matsumoto, Ayato Sugiyama, Kei Kanie, Masakatsu Watanabe, Hailing Huang, Manahil Ali, Yuki Ito, Jiro Miura, Yujiro Hirose, Koichiro Uto, Mitsuhiro Ebara, Ryuji Kato, Aika Yamawaki-Ogata, Yuji Narita, Shigetada Kawabata, Yusuke Takahashi, Mikako Hayashi

Polymers　Vol. 12　No. 4　p. 937-937　2020/04/17　Research paper (scientific journal)

Genetic characterization of Streptococcus pyogenes emm89 strains isolated in Japan from 2011 to 2019.

Hirose Y., Yamaguchi M., Takemoto N., Miyoshi-Akiyama T., Sumitomo T., Nakata M., Ikebe T., Hanada T., Yamaguchi T., Kawahara R., Okuno R., Otsuka H., Matsumoto Y., Terashima Y., Kazawa Y., Nakanishi N., Uchida K., Akiyama Y., Iwabuchi K., Nakagawa C., Yamamoto K., Nizet V., Kawabata S.

Infectious Microbes & Diseases　Vol. 2　No. 4　p. 160-166　2020　Research paper (scientific journal)

Thermosensitive pilus production by FCT type 3 Streptococcus pyogenes controlled by Nra regulator translational efficiency.

Nakata M, Sumitomo T, Patenge N, Kreikemeyer B, Kawabata S

Molecular Microbiology　2019/12　Research paper (scientific journal)

Streptococcus pneumoniaeのコリン結合タンパク質が感染成立に果たす役割

後藤花奈, 山口雅也, 川端重忠

大阪大学歯学雑誌　2019/12　Research paper (scientific journal)

Streptococcus pyogenes transcriptome changes in the inflammatory environment of necrotizing fasciitis

Yujiro Hirose, Masaya Yamaguchi, Daisuke Okuzaki, Daisuke Motooka, Hiroshi Hamamoto, Tomoki Hanada, Tomoko Sumitomo, Masanobu Nakata, Shigetada Kawabata

Applied and Environmental Microbiology　Vol. 85　No. 21　2019/11/01　Research paper (scientific journal)

Streptococcus pneumoniae surface adhesin PfbA exhibits host specificity by binding to human serum albumin but not bovine, rabbit and porcine serum albumins.

Sankar S, Yamaguchi M, Kawabata S, Ponnuraj K

The Protein journal　2019/11　Research paper (scientific journal)

Restration of intact nra transcriptional regulator into serotype M18 Streptococcs pyogenes induced thermosensitive pilus production

Li Y, Nakata M, Sumitomo T, Hirose Y, Takemura M, Yamaguchi M, Okahashi N, Kawabata S

2019/10　Research paper (other academic)

Surface Pre-Reacted Glass Filler Contributes to Tertiary Dentin Formation through a Mechanism Different Than That of Hydraulic Calcium-Silicate Cement.

Motoki Okamoto, Manahil Ali, Shungo Komichi, Masakatsu Watanabe, Hailing Huang, Yuki Ito, Jiro Miura, Yujiro Hirose, Manabu Mizuhira, Yusuke Takahashi, Daisuke Okuzaki, Shigetada Kawabata, Satoshi Imazato, Mikako Hayashi

Journal of clinical medicine　Vol. 8　No. 9　p. 1440-1440　2019/09/11　Research paper (scientific journal)

Streptococcus pneumoniae evades host cell phagocytosis and limits host mortality through its cell wall anchoring protein PfbA

Yamaguchi M, Hirose Y, Takemura M, Ono M, Sumitomo T, Nakata M, Terao Y, Kawabata S

Frontiers in Cellular and Infection Microbiology　Vol. 9　2019/08　Research paper (scientific journal)

Antibacterial activity of hinokitiol against both antibiotic‐resistant and ‐susceptible pathogenic bacteria that predominate in the oral cavity and upper airways

Hisanori Domon, Takumi Hiyoshi, Tomoki Maekawa, Daisuke Yonezawa, Hikaru Tamura, Shigetada Kawabata, Katsunori Yanagihara, Osamu Kimura, Eiji Kunitomo, Yutaka Terao

Microbiology and Immunology　Vol. 63　No. 6　p. 213-222　2019/06　Research paper (scientific journal)

Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae.

Yamaguchi M, Goto K, Hirose Y, Yamaguchi Y, Sumitomo T, Nakata M, Nakano K, Kawabata S

Commun Biol　Vol. 2　2019/03

Streptococcus pneumoniae surface adhesin PfbA and its interaction with erythrocytes and hemoglobin.

Radhakrishnan D, Yamaguchi M, Kawabata S, Ponnuraj K

International Journal of Biological Macromolecules　Vol. 120　p. 135-143　2018/12　Research paper (scientific journal)

Streptococcus pyogenes CAMP factor promotes calcium ion uptake in RAW264.7 cells.

Kurosawa M, Oda M, Domon H, Isono T, Nakamura Y, Saitoh I, Hayasaki H, Yamaguchi M, Kawabata S, Terao Y

Microbiology and Immunology　Vol. 62　No. 10　p. 617-623　2018/10　Research paper (scientific journal)

化膿レンサ球菌におけるヒアルロン酸分解酵素の分子系統解析およびタンパク質構造解析

東 孝太郎, 武部 克希, 山口 雅也, 住友 倫子, 中田 匡宣, 鈴木 守, 川端 重忠

Journal of Oral Biosciences Supplement　Vol. 2018　p. 351-351　2018/09

Streptococcus sanguinis が産生する細胞壁架橋型線毛の構成因子

李怡萱, 中田匡宣, 岡橋暢夫, 山口雅也, 住友倫子, 川端重忠

2018/09　Research paper (other academic)

Streptococcal H2O2 inhibits IgE-triggered degranulation by damaging on mast cells

Okahashi N, Nakata M, HIrose Y, Kuwata H, Kawabata S

2018/09　Research paper (other academic)

Competence-induced protein Ccs4 facilitates pneumococcal invasion into brain tissue and virulence in meningitis

Hirose Y, Yamaguchi M, Goto K, Sumitomo T, Nakata M, Kawabata S

Virulence　Vol. 9　p. 1576-1587　2018/09　Research paper (scientific journal)

Comparison of trophic factors secreted from human adipose-derived stromal vascular fraction with those from adipose-derived stromal/stem cells in the same individuals

Yujiro Hirose, Yasuhito Funahashi, Yoshihisa Matsukawa, Tsuyoshi Majima, Masaya Yamaguchi, Shigetada Kawabata, Momokazu Gotoh, Tokunori Yamamoto

Cytotherapy　Vol. 20　No. 4　p. 589-591　2018/04/01　Research paper (scientific journal)

Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4.

Kosuke Nagai, Hisanori Domon, Tomoki Maekawa, Masataka Oda, Takumi Hiyoshi, Hikaru Tamura, Daisuke Yonezawa, Yoshiaki Arai, Mai Yokoji, Koichi Tabeta, Rie Habuka, Akihiko Saitoh, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao

Cellular immunology　Vol. 325　p. 14-22　2018/03　Research paper (scientific journal)

Role of streptococcal polysaccharide capsules and glycosidases in the pathogenesis

Vol. 90　No. 1　p. 80-83　2018/02

Streptococcal cysteine protease-mediated cleavage of desmogleins is involved in the pathogenesis of cutaneous infection

Tomoko Sumitomo, Yasushi Mori, Yuumi Nakamura, Mariko Honda-Ogawa, Seitaro Nakagawa, Masaya Yamaguchi, Hiroyuki Matsue, Yutaka Terao, Masanobu Nakata, Shigetada Kawabata

Frontiers in Cellular and Infection Microbiology　Vol. 8　No. 8　2018/01/24　Research paper (scientific journal)

Erratum to "Characterizations of oral microbiota in elderly nursing home residents with diabetes".

Ogawa T, Honda-Ogawa M, Ikebe K, Notomi Y, Iwamoto Y, Shirobayashi I, Hata S, Kibi M, Masayasu S, Sasaki S, Kawabata S, Maeda Y

Journal of oral science　Vol. 60　No. 1　2018

Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4.

Nagai K, Domon H, Maekawa T, Oda M, Hiyoshi T, Tamura H, Yonezawa D, Arai Y, Yokoji M, Tabeta K, Habuka R, Saitoh A, Yamaguchi M, Kawabata S, Terao Y

Cellular Immunology　Vol. 325　p. 14-22　2018/01　Research paper (scientific journal)

Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia.

Hisanori Domon, Kosuke Nagai, Tomoki Maekawa, Masataka Oda, Daisuke Yonezawa, Wataru Takeda, Takumi Hiyoshi, Hikaru Tamura, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao

Frontiers in immunology　Vol. 9　p. 732-732　2018　Research paper (scientific journal)

Composition of salivary microbiota in elderly subjects

Ogawa T, Hirose Y, Honda-Ogawa M, Sugimoto M, Sasaki S, Kibi M, Kawabata S, Ikebe K, Maeda Y

Scientific reports　Vol. 8　No. 1　2018/01　Research paper (scientific journal)

Streptococcus pyogenes CAMP factor promotes bacterial adhesion and invasion in pharyngeal epithelial cells without serum via PI3K/Akt signaling pathway.

Mie Kurosawa, Masataka Oda, Hisanori Domon, Toshihito Isono, Yuki Nakamura, Issei Saitoh, Haruaki Hayasaki, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao

Microbes and infection　Vol. 20　No. 1　p. 9-18　2018/01　Research paper (scientific journal)

Comparison of antimicrobial spectrum and mechanisms of organic virgin coconut oil and lauric acid against bacteria.

Nagase S, Matsue M, Mori Y, Honda-Ogawa M, Sugitani K, Sumitomo T, Nakata M, Kawabata S, Okamoto S

Journal of Wellness and Health Care　Vol. 41　No. 1　p. 87-95　2017/11　Research paper (scientific journal)

Streptococcus pneumoniae surface protein PfbA is a versatile multidomain and multiligand-binding adhesin employing different binding mechanisms

Darwin Selvi Jemima Beulin, Deepthi Radhakrishnan, Sharanya C. Suresh, Chittalakottu Sadasivan, Masaya Yamaguchi, Shigetada Kawabata, Karthe Ponnuraj

FEBS JOURNAL　Vol. 284　No. 20　p. 3404-3421　2017/10　Research paper (scientific journal)

Microbiological assessment of effects of clinical mouth rinses on common oral microbes

Taiji Ogawa, Mariko Honda-Ogawa, Kazunori Ikebe, Shigetada Kawabata, Yoshinobu Maeda

JOURNAL OF ORAL SCIENCE　Vol. 59　No. 3　p. 391-395　2017/09　Research paper (scientific journal)

Streptococcus pyogenes Phospholipase A(2) Induces the Expression of Adhesion Molecules on Human Umbilical Vein Endothelial Cells and Aorta of Mice

Masataka Oda, Hisanori Domon, Mie Kurosawa, Toshihito Isono, Tomoki Maekawa, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY　Vol. 7　No. 7　2017/06　Research paper (scientific journal)

Streptococcus pyogenes Endopeptidase O Contributes to Evasion from Complement-mediated Bacteriolysis via Binding to Human Complement Factor C1q

Mariko Honda-Ogawa, Tomoko Sumitomo, Yasushi Mori, Dalia Talat Hamd, Taiji Ogawa, Masaya Yamaguchi, Masanobu Nakata, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 292　No. 10　p. 4244-4254　2017/03　Research paper (scientific journal)

Streptococcus sanguinis induces neutrophil cell death by production of hydrogen peroxide

Ryuichi Sumioka, Masanobu Nakata, Nobuo Okahashi, Yixuan Li, Satoshi Wada, Masaya Yamaguchi, Tomoko Sumitomo, Mikako Hayashi, Shigetada Kawabata

PLOS ONE　Vol. 12　No. 2　2017/02　Research paper (scientific journal)

Hydrogen peroxide produced by oral streptococci induces macrophage cell death

Okahashi, N, Nakata, M, Kuwata, H, Kawabata, S

2017/01　Research paper (bulletin of university, research institution)

Characterizations of oral microbiota in elderly nursing home residents with diabetes

Taiji Ogawa, Mariko Honda-Ogawa, Kazunori Ikebe, Yumiko Notomi, Yoshiko Iwamoto, Itsuki Shirobayashi, Seiko Hata, Masahito Kibi, Shizuko Masayasu, Satoshi Sasaki, Shigetada Kawabata, Yoshinobu Maeda

Journal of Oral Science　Vol. 59　No. 4　p. 549-555　2017　Research paper (scientific journal)

Zinc metalloproteinase ZmpC suppresses experimental pneumococcal meningitis by inhibiting bacterial invasion of central nervous systems

Masaya Yamaguchi, Masanobu Nakata, Ryuichi Sumioka, Yujiro Hirose, Satoshi Wada, Yukihiro Akeda, Tomoko Sumitomo, Shigetada Kawabata

VIRULENCE　Vol. 8　No. 8　p. 1516-1524　2017　Research paper (scientific journal)

Degradation of bradykinin by a metalloendopeptidase from Streptococcus pyogenes

Yoichi Miyamoto, Takaaki Akaike, Shigetada Kawabata, Teruo Akuta, Chiho Taruki, Jun Yoshitake, Shigeyuki Hamada, Fusao Ota, Hideo Igarashi, Kentaro Yoshimura, Ryutaro Kamijo, Hiroshi Maeda

Journal of Oral Biosciences　Vol. 58　No. 4　p. 167-172　2016/11/01　Research paper (scientific journal)

Streptococcal Enolase and Immune Evasion

Masaya Yamaguchi, Shigetada Kawabata

Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections　p. 269-289　2016/10/03　Part of collection (book)

Lysine and Threonine Biosynthesis from Aspartate Contributes to Staphylococcus aureus Growth in Calf Serum

Yuichi Oogai, Masaya Yamaguchi, Miki Kawada-Matsuo, Tomoko Sumitomo, Shigetada Kawabata, Hitoshi Komatsuzawa

APPLIED AND ENVIRONMENTAL MICROBIOLOGY　Vol. 82　No. 20　p. 6150-6157　2016/10　Research paper (scientific journal)

Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen Peroxide

Nobuo Okahashi, Masanobu Nakata, Hirotaka Kuwata, Shigetada Kawabata

INFECTION AND IMMUNITY　Vol. 84　No. 7　p. 2042-2050　2016/07　Research paper (scientific journal)

Evolutionary inactivation of a sialidase in group B Streptococcus

Masaya Yamaguchi, Yujiro Hirose, Masanobu Nakata, Satoshi Uchiyama, Yuka Yamaguchi, Kana Goto, Tomoko Sumitomo, Amanda L. Lewis, Shigetada Kawabata, Victor Nizet

SCIENTIFIC REPORTS　Vol. 6　2016/06　Research paper (scientific journal)

Effects of Extracellular pH on Dental Pulp Cells In Vitro

Yujiro Hirose, Masaya Yamaguchi, Shigetada Kawabata, Masashi Murakami, Misako Nakashima, Momokazu Gotoh, Tokunori Yamamoto

JOURNAL OF ENDODONTICS　Vol. 42　No. 5　p. 735-741　2016/05　Research paper (scientific journal)

Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions

Tomoko Sumitomo, Masanobu Nakata, Miharu Higashino, Masaya Yamaguchi, Shigetada Kawabata

SCIENTIFIC REPORTS　Vol. 6　2016/01　Research paper (scientific journal)

Injection of Dental Pulp Stem Cells Promotes Healing of Damaged Bladder Tissue in a Rat Model of Chemically Induced Cystitis

Yujiro Hirose, Tokunori Yamamoto, Misako Nakashima, Yasuhito Funahashi, Yoshihisa Matsukawa, Masaya Yamaguehi, Shigetada Kawabata, Momokazu Gotoh

CELL TRANSPLANTATION　Vol. 25　No. 3　p. 425-436　2016　Research paper (scientific journal)

Molecular and genomic characterization of pathogenic traits of group A Streptococcus pyogenes.

Hamada S, Kawabata S, d. Nakagawa I

Proceedings of the Japan Academy　Vol. 91　No. 10　p. 539-559　2015/10

Role of Streptococcus sanguinis cell wall-anchored nuclease

Morita C, Nakata M, Sumioka R, Okahashi N, Hamada S, Sumitomo T, Kawabata S

2014/11　Research paper (other academic)

Type 2 pili of oral streptococci

N. Okahashi, M. Nakata, S. Kawabata

2014/09　Research paper (other academic)

Hydrogen peroxide produced by Streptococcus sanguinis induces NETs

R. Sumioka, M. Nakata, C. Morita, K, Wada, N. Okahashi, T. Sumitomo, M. Yamaguchi, M. Hayashi, S. Kawabata

58th Annual Meeting of The Japanese Association for Oral Biology (Sapporo)　2014/09　Research paper (other academic)

Cell wall associated nuclease of Streptococcus sanguinis

C. Morita, R. Sumioka, M. Nakata, K. Wada, N. Okahashi, T. Sumitomo, M. Yamaguchi, T. Yamashiro, S. Kawabata

2014/09　Research paper (other academic)

Cell Wall-Anchored Nuclease of Streptococcus sanguinis Contributes to Escape from Neutrophil Extracellular Trap-Mediated Bacteriocidal Activity

Chisato Morita, Ryuichi Sumioka, Masanobu Nakata, Nobuo Okahashi, Satoshi Wada, Takashi Yamashiro, Mikako Hayashi, Shigeyuki Hamada, Tomoko Sumitomo, Shigetada Kawabata

PLOS ONE　Vol. 9　No. 8　2014/08　Research paper (scientific journal)

Cell wall-anchored nucelase of Streptococcus sanguinis contributes to evasion of innate immunity

Morita, C, Sumioka, R, Nakata, M, Sumitomo, T, Okahashi, N, Hamada, S, Kawabata, S

2014/03　Research paper (other academic)

Crystal structure of PfbA, a surface adhesin of Streptococcus pneumoniae, provides hints into its interaction with fibronectin

D. S. Jemima Beulin, Masaya Yamaguchi, Shigetada Kawabata, Karthe Ponnuraj

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES　Vol. 64　p. 168-173　2014/03　Research paper (scientific journal)

Erratum: Streptococcus pneumoniae Invades Erythrocytes and Utilizes Them to Evade Human Innate Immunity (PLoS ONE (2014) 9:1 (10.1371/annotation/de14e562- d899-48da-b677-ca61cca2cf5b))

Masaya Yamaguchi, Yutaka Terao, Yuka Mori-Yamaguchi, Hisanori Domon, Yuuki Sakaue, Tetsuya Yagi, Kunihiko Nishino, Akihito Yamaguchi, Victor Nizet, Shigetada Kawabata

PLoS ONE　Vol. 9　No. 1　2014/01/15　Research paper (scientific journal)

Hydrogen Peroxide Contributes to the Epithelial Cell Death Induced by the Oral Mitis Group of Streptococci

Nobuo Okahashi, Tomoko Sumitomo, Masanobu Nakata, Atsuo Sakurai, Hirotaka Kuwata, Shigetada Kawabata

PLOS ONE　Vol. 9　No. 1　2014/01　Research paper (scientific journal)

Cell binding nuclease of Streptococcus sanguinis contributes to an evasion from host innate immunity

Sumioka R, Morita T, Nakata M, Okahashi N, Sumitomo T, kawabata S

2013/09　Research paper (other academic)

Hydrogen peroxide is unrecognized virulent factor of oral streptococci

Okahashi N, Okinaga T, Sakurai A, Terao Y, Nakata M, Kawabata S, Nishihara T

2013/09　Research paper (other academic)

Group A streptococcal cysteine protease cleaves epithelial junctions and contributes to bacterial translocation

Tomoko Sumitomo, Masanobu Nakata, Miharu Higashino, Yutaka Terao, Shigetada Kawabata

Journal of Biological Chemistry　Vol. 288　No. 19　p. 13317-13324　2013/05/10　Research paper (scientific journal)

Cysteine Proteinase from Streptococcus pyogenes Enables Evasion of Innate Immunity via Degradation of Complement Factors

Mariko Honda-Ogawa, Taiji Ogawa, Yutaka Terao, Tomoko Sumitomo, Masanobu Nakata, Kazunori Ikebe, Yoshinobu Maeda, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 288　No. 22　p. 15854-15864　2013/05　Research paper (scientific journal)

Hydrogen Peroxide Produced by Oral Streptococci Induces Macrophage Cell Death

Nobuo Okahashi, Masanobu Nakata, Tomoko Sumitomo, Yutaka Terao, Shigetada Kawabata

PLOS ONE　Vol. 8　No. 5　2013/05　Research paper (scientific journal)

Pleiotropic virulence factor - Streptococcus pyogenes fibronectin-binding proteins

Masaya Yamaguchi, Yutaka Terao, Shigetada Kawabata

Cellular Microbiology　Vol. 15　No. 4　p. 503-511　2013/04　Research paper (scientific journal)

MicroRNA fragments derived from Streptococcus pyogenes enable activation of neutrophil phagocytosis: In vitro study

Taiji Ogawa, Yutaka Terao, Mariko Honda-Ogawa, Sakae Hashimoto, Kazunori Ikebe, Yoshinobu Maeda, Shigetada Kawabata

Microbes and Infection　Vol. 15　No. 3　p. 212-218　2013/03　Research paper (scientific journal)

Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity.

Masaya Yamaguchi, Yutaka Terao, Yuka Mori-Yamaguchi, Hisanori Domon, Yuuki Sakaue, Tetsuya Yagi, Kunihiko Nishino, Akihito Yamaguchi, Victor Nizet, Shigetada Kawabata

PloS one　Vol. 8　No. 10　2013　Research paper (scientific journal)

Identification and characterization of a collagen-binding protein, Cbm, in Streptococcus mutans

R. Nomura, K. Nakano, S. Naka, H. Nemoto, K. Masuda, J. Lapirattanakul, S. Alaluusua, M. Matsumoto, S. Kawabata, T. Ooshima

MOLECULAR ORAL MICROBIOLOGY　Vol. 27　No. 4　p. 308-323　2012/08　Research paper (scientific journal)

Evolution of Cariogenic Character in Streptococcus mutans: Horizontal Transmission of Glycosyl Hydrolase Family 70 Genes

Tomonori Hoshino, Taku Fujiwara, Shigetada Kawabata

Scientific Reports　Vol. 2　2012/07/18　Research paper (scientific journal)

Group A Streptococcus Adheres to Pharyngeal Epithelial Cells with Salivary Proline-rich Proteins via GrpE Chaperone Protein

Jumpei Murakami, Yutaka Terao, Ichijiro Morisaki, Shigeyuki Hamada, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 287　No. 26　p. 22266-22275　2012/06　Research paper (scientific journal)

alpha-Enolase of Streptococcus pneumoniae Induces Formation of Neutrophil Extracellular Traps

Yuka Mori, Masaya Yamaguchi, Yutaka Terao, Shigeyuki Hamada, Takashi Ooshima, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 287　No. 13　p. 10472-10481　2012/03　Research paper (scientific journal)

Long-term survival of salivary streptococci on dental devices made of ethylene vinyl acetate

Taiji Ogawa, Sayaka Yamasaki, Mariko Honda, Yutaka Terao, Shigetada Kawabata, Yoshinobu Maeda

INTERNATIONAL JOURNAL OF ORAL SCIENCE　Vol. 4　No. 1　p. 14-18　2012/03　Research paper (scientific journal)

Involvement of T6 Pili in Biofilm Formation by Serotype M6 Streptococcus pyogenes

Keiji Richard Kimura, Masanobu Nakata, Tomoko Sumitomo, Bernd Kreikemeyer, Andreas Podbielski, Yutaka Terao, Shigetada Kawabata

JOURNAL OF BACTERIOLOGY　Vol. 194　No. 4　p. 804-812　2012/02　Research paper (scientific journal)

S-Carboxymethylcysteine inhibits adherence of Streptococcus pneumoniae to human alveolar epithelial cells

Tomoko Sumitomo, Masanobu Nakata, Masaya Yamaguchi, Yutaka Terao, Shigetada Kawabata

JOURNAL OF MEDICAL MICROBIOLOGY　Vol. 61　No. 1　p. 101-108　2012/01　Research paper (scientific journal)

Streptococcus sanguinis induces foam cell formation and cell death of macrophages in association with production of reactive oxygen species

Nobuo Okahashi, Toshinori Okinaga, Atsuo Sakurai, Yutaka Terao, Masanobu Nakata, Keisuke Nakashima, Seikou Shintani, Shigetada Kawabata, Takashi Ooshima, Tatsuji Nishihara

FEMS MICROBIOLOGY LETTERS　Vol. 323　No. 2　p. 164-170　2011/10　Research paper (scientific journal)

Assembly Mechanism of FCT Region Type 1 Pili in Serotype M6 Streptococcus pyogenes

Masanobu Nakata, Keiji Richard Kimura, Tomoko Sumitomo, Satoshi Wada, Akinari Sugauchi, Eiji Oiki, Miharu Higashino, Bernd Kreikemeyer, Andreas Podbielski, Nobuo Okahashi, Shigeyuki Hamada, Ryutaro Isoda, Yutaka Terao, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 286　No. 43　p. 37566-37577　2011/10　Research paper (scientific journal)

Oral-Nasopharyngeal Dendritic Cells Mediate T Cell-Independent IgA Class Switching on B-1 B Cells

Kosuke Kataoka, Keiko Fujihashi, Yutaka Terao, Rebekah S. Gilbert, Shinichi Sekine, Ryoki Kobayashi, Yoshiko Fukuyama, Shigetada Kawabata, Kohtaro Fujihashi

PLOS ONE　Vol. 6　No. 9　2011/09　Research paper (scientific journal)

Novel Epitopic Region of Glucosyltransferase B from Streptococcus mutans

Hoshino T, Kondo Y, Saito K, Terao Y, Okahashi N, Kawabata S, Fujiwara T

Clinical and Vaccine Immunology　Vol. 18　No. 9　p. 1552-61　2011/09　Research paper (scientific journal)

Mucosal immune features to phosphorylcholine by nasal Flt3 ligand cDNA-based vaccination

Tselmeg Baatarjav, Kosuke Kataoka, Rebekah S. Gilbert, Yutaka Terao, Makoto Fukui, Masaki Goto, Shigetada Kawabata, Masafumi Yamamoto, Kohtaro Fujihashi, Hiro-O Ito

VACCINE　Vol. 29　No. 34　p. 5747-5757　2011/08　Research paper (scientific journal)

The Nasal Dendritic Cell-Targeting Flt3 Ligand as a Safe Adjuvant Elicits Effective Protection against Fatal Pneumococcal Pneumonia

Kosuke Kataoka, Kohtaro Fujihashi, Keita Oma, Yoshiko Fukuyama, Susan K. Hollingshead, Shinichi Sekine, Shigetada Kawabata, Hiro-O Ito, David E. Briles, Kazunori Oishi

INFECTION AND IMMUNITY　Vol. 79　No. 7　p. 2819-2828　2011/07　Research paper (scientific journal)

Biofilm formation or internalization into epithelial cells enable Streptococcus pyogenes to evade antibiotic eradication in patients with pharyngitis

Taiji Ogawa, Yutaka Terao, Hisashi Okuni, Keiko Ninomiya, Hiroshi Sakata, Kazunori Ikebe, Yoshinobu Maeda, Shigetada Kawabata

MICROBIAL PATHOGENESIS　Vol. 51　No. 1-2　p. 58-68　2011/07　Research paper (scientific journal)

Epidemiological characterization of Streptococcus pyogenes isolated from patients with multiple onsets of pharyngitis

Taiji Ogawa, Yutaka Terao, Hiroshi Sakata, Hisashi Okuni, Keiko Ninomiya, Kazunori Ikebe, Yoshinobu Maeda, Shigetada Kawabata

FEMS MICROBIOLOGY LETTERS　Vol. 318　No. 2　p. 143-151　2011/05　Research paper (scientific journal)

Pili of oral Streptococcus sanguinis bind to salivary amylase and promote the biofilm formation

Nobuo Okahashi, Masanobu Nakata, Yutaka Terao, Ryutaro Isoda, Atsuo Sakurai, Tomoko Sumitomo, Masaya Yamaguchi, Richard K. Kimura, Eiji Oiki, Shigetada Kawabata, Takashi Ooshima

MICROBIAL PATHOGENESIS　Vol. 50　No. 3-4　p. 148-154　2011/03　Research paper (scientific journal)

Inhibitory Effects of Oenothera biennis (Evening Primrose) Seed Extract on Streptococcus mutans and S. mutans-Induced Dental Caries in Rats

M. Matsumoto-Nakano, K. Nagayama, H. Kitagori, K. Fujita, S. Inagaki, Y. Takashima, M. Tamesada, S. Kawabata, T. Ooshima

CARIES RESEARCH　Vol. 45　No. 1　p. 56-63　2011　Research paper (scientific journal)

Streptolysin S Contributes to Group A Streptococcal Translocation across an Epithelial Barrier

Tomoko Sumitomo, Masanobu Nakata, Miharu Higashino, Yingji Jin, Yutaka Terao, Yukako Fujinaga, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 286　No. 4　p. 2750-2761　2011/01　Research paper (scientific journal)

歯科用インプラントと感染症

山口 雅也, 寺尾 豊, 川端 重忠

歯界展望　2010/12

肺炎レンサ球菌 最新の知見

山口 雅也, 寺尾 豊, 川端 重忠

大阪大学歯学雑誌　2010/04

Characterization of pili from oral Streptococcus sanguinis

Okahashi, N, Nakata, M, Sakurai, A, Terao, Y, Yamaguchi, M, Hoshino, T, Kawabata, S, Ooshima, T

2010/03　Research paper (other academic)

Streptococcus pneumoniae Evades Neutrophil phagocytosis Through its Surface Protein PfbA

M. Yamaguchi, Y. Terao, K. Nishino, A. Yamaguchi, S. Hamada, S. Kawabata

2010/03　Research paper (international conference proceedings)

Fusobacterium nucleatum Envelope Protein FomA Is Immunogenic and Binds to the Salivary Statherin-Derived Peptide

Hidetaka Nakagaki, Shinichi Sekine, Yutaka Terao, Masahiro Toe, Muneo Tanaka, Hiro-O Ito, Shigetada Kawabata, Satoshi Shizukuishi, Kohtaro Fujihashi, Kosuke Kataoka

INFECTION AND IMMUNITY　Vol. 78　No. 3　p. 1185-1192　2010/03　Research paper (scientific journal)

Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion

Nobuo Okahashi, Masanobu Nakata, Atsuo Sakurai, Yutaka Terao, Tomonori Hoshino, Masaya Yamaguchi, Ryutaro Isoda, Tomoko Sumitomo, Kazuhiko Nakano, Shigetada Kawabata, Takashi Ooshima

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 391　No. 2　p. 1192-1196　2010/01　Research paper (scientific journal)

Nrc of Streptococcus pneumoniae suppresses capsule expression and enhances anti-phagocytosis

Masaya Yamaguchi, Yuki Minamide, Yutaka Terao, Ryutaro Isoda, Taiji Ogawa, Shin-ichi Yokota, Shigeyuki Hamada, Shigetada Kawabata

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 390　No. 1　p. 155-160　2009/12　Research paper (scientific journal)

Invasion and adherence of oral streptococcus to oral epithelial cells

Sakurai, A, Okahashi, N, Nakata, M, Terao, Y, Maruyama, F, Kawabata, S, Ooshima, T

2009/09　Research paper (other academic)

Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific content

Fumito Maruyama, Mitsuhiko Kobata, Ken Kurokawa, Keishin Nishida, Atsuo Sakurai, Kazuhiko Nakano, Ryota Nomura, Shigetada Kawabata, Takashi Ooshima, Kenta Nakai, Masahira Hattori, Shigeyuki Hamada, Ichiro Nakagawa

BMC GENOMICS　Vol. 10　2009/08　Research paper (scientific journal)

Mechanisms of immune evasion by Streptococcus pyogenes.

Terao Y, Kawabata S

Tanpakushitsu Kakusan Koso. Protein, Nucleic acid, Enzyme　Vol. 54　No. 8 Suppl　p. 982-987　2009/06

Molecular and biological characterization of gtf regulation-associated genes in Streptococcus mutans

Y. Terao, R. Isoda, J. Murakami, S. Hamada, S. Kawabata

ORAL MICROBIOLOGY AND IMMUNOLOGY　Vol. 24　No. 3　p. 211-217　2009/06　Research paper (scientific journal)

肺炎レンサ球菌の新規ワクチン抗原の検索

山口 雅也, 寺尾 豊, 川端 重忠

大阪大学歯学雑誌　Vol. 53　No. 2　p. 61-65　2009/04

Dendritic cell-targeting DNA-based mucosal adjuvants for the development of mucosal vaccines.

Kataoka K, Fujihashi K. Oma K, Fukuyama Y, Hollingshead S. K, Sekine S, Kawabata S, Ito H.-O, Briles D. E, Oishi K

Expert Reviews of Vaccines　Vol. 8　No. 9　p. 1183-1193　2009　Research paper (scientific journal)

Mode of Expression and Functional Characterization of FCT-3 Pilus Region-Encoded Proteins in Streptococcus pyogenes Serotype M49

Masanobu Nakata, Thomas Koeller, Karin Moritz, Deborah Ribardo, Ludwig Jonas, Kevin S. McIver, Tomoko Sumitomo, Yutaka Terao, Shigetada Kawabata, Andreas Podbielski, Bernd Kreikemeyer

INFECTION AND IMMUNITY　Vol. 77　No. 1　p. 32-44　2009/01　Research paper (scientific journal)

PfbA, a Novel Plasmin- and Fibronectin-binding Protein of Streptococcus pneumoniae, Contributes to Fibronectin-dependent Adhesion and Antiphagocytosis

Masaya Yamaguchi, Yutaka Terao, Yuka Mori, Shigeyuki Hamada, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 283　No. 52　p. 36272-36279　2008/12　Research paper (scientific journal)

A novel streptococcal leucine zipper protein (Lzp) binds to human immunoglobulins

Shigefumi Okamoto, Yutaka Terao, Kohei Hasuike, Shigeyuki Hamada, Shigetada Kawabata

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 377　No. 4　p. 1128-1134　2008/12　Research paper (scientific journal)

PfbA, a Novel Plasmin- and Fibronectin-binding Protein of Streptococcus pneumoniae, Contributes to Fibronectin-dependent Adhesion and Antiphagocytosis

Masaya Yamaguchi, Yutaka Terao, Yuka Mori, Shigeyuki Hamada, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 283　No. 52　p. 36272-36279　2008/12　Research paper (scientific journal)

Molecular cloning of novel Monad binding protein containing tetratricopeptide repeat domains

Yuki Itsuki, Makio Saeki, Hirokazu Nakahara, Hiroshi Egusa, Yasuyuki Irie, Yutaka Terao, Shigetada Kawabata, Hirofumi Yatani, Yoshinori Kamisaki

FEBS Letters　Vol. 582　No. 16　p. 2365-2370　2008/07/09　Research paper (scientific journal)

Streptococcal immunoglobulin-binding protein Sib35 exerts stimulatory and mitogenic effects toward mouse B lymphocytes

Shigefumi Okamoto, Yutaka Terao, Yasuharu Tamura, Shigeyuki Hamada, Shigetada Kawabata

FEMS MICROBIOLOGY LETTERS　Vol. 281　No. 1　p. 73-80　2008/04　Research paper (scientific journal)

Molecular and biological characterization of histidine triad protein in group A streptococci

Eiji Kunitomo, Yutaka Terao, Shigefumi Okamoto, Tetsuya Rikimaru, Shigeyuki Hamada, Shigetada Kawabata

MICROBES AND INFECTION　Vol. 10　No. 4　p. 414-423　2008/04　Research paper (scientific journal)

Group A streptococcal cysteine protease degrades C3 (C3b) and contributes to evasion of innate immunity

Yutaka Terao, Yuka Mori, Masaya Yamaguchi, Yoshikata Shimizu, Kenji Ooe, Shigeyuki Hamada, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 283　No. 10　p. 6253-6260　2008/03　Research paper (scientific journal)

The Streptococcus pyogenes serotype m49 nra-ralp3 transcriptional regulatory network and its control of virulence factor expression from the novel eno ralp3 epf sagA pathogenicity region

Bernd Kreikemeyer, Masanobu Nakata, Thomas Koller, Hendrikje Hildisch, Vassilios Kourakos, Kerstin Standar, Shigetada Kawabata, Michael O. Glocker, Andreas Podbielski

INFECTION AND IMMUNITY　Vol. 75　No. 12　p. 5698-5710　2007/12　Research paper (scientific journal)

A群レンサ球菌感染症のメカニズム

川端 重忠, 山口 雅也

医学のあゆみ　2007/11

Calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation

Makio Saeki, Yasuyuki Irie, Lin Ni, Yuki Itsuki, Yutaka Terao, Shigetada Kawabata, Yoshinori Kamisaki

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 282　No. 16　p. 11786-11794　2007/04　Research paper (scientific journal)

Inflammatory immune responses by Water-insoluble alpha-glucans

S. Okamoto, Y. Terao, H. Kaminishi, S. Hamada, S. Kawabata

JOURNAL OF DENTAL RESEARCH　Vol. 86　No. 3　p. 242-248　2007/03　Research paper (scientific journal)

Role of Streptococcus sanguinis sortase A in bacterial colonization

Masaya Yamaguchi, Yutaka Terao, Taiji Ogawa, Toshihito Takahashi, Shigeyuki Hamada, Shigetada Kawabata

Microbes and Infection　Vol. 8　No. 12-13　p. 2791-2796　2006/10　Research paper (scientific journal)

Multifunctional glyceraldehyde-3-phosphate dehydrogenase of Streptococcus pyogenes is essential for evasion from neutrophils

Yutaka Terao, Masaya Yamaguchi, Shigeyuki Hamada, Shigetada Kawabata

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 281　No. 20　p. 14215-14223　2006/05　Research paper (scientific journal)

Protective immunity against Streptococcus pyogenes challenge in mice after immunization with fibronectin-binding protein

Y Terao, S Okamoto, K Kataoka, S Hamada, S Kawabata

JOURNAL OF INFECTIOUS DISEASES　Vol. 192　No. 12　p. 2081-2091　2005/12　Research paper (scientific journal)

Systemic immunization with streptococcal immunoglobulin-binding protein Sib35 induces protective immunity against group A Streptococcus challenge in mice

S Okamoto, Y Tamura, Y Terao, S Hamada, S Kawabata

VACCINE　Vol. 23　No. 40　p. 4852-4859　2005/09　Research paper (scientific journal)

Silkworm-Pathogenic Bacteria Infection Model for Identification of Novel Virulence Genes

Kaito C, Kurokawa K, Matsumoto Y, Terao Y, Kawabata S, Hamada S, Sekimizu K

Molecular Microbiology　Vol. 56　No. 4　p. 934-44　2005/05　Research paper (scientific journal)

Genetic analysis and virulence factors of group A streptococci that cause severe invasive infectious diseases.

Hamada S, Nakagawa I, Kawabata S

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 50　No. 3　p. 253-261　2005/03

Search for calcineurin B binding proteins by yeast two-hybrid system.

Yoshida M, Saeki M, Itsuki Y, Irie Y, Terao Y, Kawabata S, Hamada S, Niwa H, Kamisaki Y

Journal of Pharmaceutical Sciences　Vol. 97　p. 217-217　2005

Synergistic effects of streptococcal glucosyltransferases on adhesive biofilm formation

M Tamesada, S Kawabata, T Fujiwara, S Hamada

JOURNAL OF DENTAL RESEARCH　Vol. 83　No. 11　p. 874-879　2004/11　Research paper (scientific journal)

The Streptococcus pyogenes Capsule Is Required for Adhesion of Bacteria to Virus-Infected Alveolar Epithelia Cells and Lethal Bacterial-Viral Superinfection

Okamoto S, Kawabata S, Terao Y, Fujitaka H, Okuno Y, Hamada S

Infection and Immunity　2004/10　Research paper (scientific journal)

Transcriptome analysis and gene expression profiles of early apoptosis-related genes in Streptococcus pyogenes-infected epithelial cells

Nakagawa, I, M Nakata, S Kawabata, S Hamada

CELLULAR MICROBIOLOGY　Vol. 6　No. 10　p. 939-952　2004/10　Research paper (scientific journal)

Proapoptotic effect of proteolytic activation of matrix metalloproteinases by Streptococcus pyogenes thiol proteinase (Streptococcus pyrogenic exotoxin B)

F Tamura, R Nakagawa, T Akuta, S Okamoto, S Hamada, H Maeda, S Kawabata, T Akaike

INFECTION AND IMMUNITY　Vol. 72　No. 8　p. 4836-4847　2004/08　Research paper (scientific journal)

Vaccination with formalin-inactivated influenza vaccine protects mice against lethal influenza Streptococcus pyogenes superinfection

S Okamoto, S Kawabata, H Fujitaka, T Uehira, Y Okuno, S Hamada

VACCINE　Vol. 22　No. 21-22　p. 2887-2893　2004/07　Research paper (scientific journal)

Streptococcus pyogenes infection induces septic arthritis with increased production of the receptor activator of the NF-kappa B ligand

A Sakurai, N Okahashi, Nakagawa, I, S Kawabata, A Amano, T Ooshima, S Hamada

INFECTION AND IMMUNITY　Vol. 71　No. 10　p. 6019-6026　2003/10　Research paper (scientific journal)

Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution

Nakagawa, I, K Kurokawa, A Yamashita, M Nakata, Y Tomiyasu, N Okahashi, S Kawabata, K Yamazaki, T Shiba, T Yasunaga, H Hayashi, M Hattori, S Hamada

GENOME RESEARCH　Vol. 13　No. 6　p. 1042-1055　2003/06　Research paper (scientific journal)

Influenza A virus-infected hosts boost an invasive type of Streptococcus pyogenes infection in mice

S Okamoto, S Kawabata, Nakagawa, I, Y Okuno, T Goto, K Sano, S Hamada

JOURNAL OF VIROLOGY　Vol. 77　No. 7　p. 4104-4112　2003/04　Research paper (scientific journal)

Infection by Streptococcus pyogenes Induces the Receptor Activator of NF-kappaB Ligand Expression in Mouse Osteoblastic Cells

Okahashi N, Sakurai A, Nakagawa I, Fujiwara T, Kawabata S, Amano A, Hamada S

Infection and immunity　Vol. 71　No. 2　p. 948-55　2003/02　Research paper (scientific journal)

Identification of a new variant of fimA gene of Porphyromonas gingivalis and its distribution in adults and disabled populations with periodontitis

Nakagawa, I, A Amano, Y Ohara-Nemoto, N Endoh, Morisaki, I, S Kimura, S Kawabata, S Hamada

JOURNAL OF PERIODONTAL RESEARCH　Vol. 37　No. 6　p. 425-432　2002/12　Research paper (scientific journal)

Molecular characterization of a novel fibronectin-binding protein of Streptococcus pyogenes strains isolated from toxic shock-like syndrome patients

Y Terao, S Kawabata, M Nakata, Nakagawa, I, S Hamada

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 277　No. 49　p. 47428-47435　2002/12　Research paper (scientific journal)

A novel, anchorless streptococcal surface protein that binds to human immunoglobulins

S Kawabata, Y Tamura, J Murakami, Y Terao, Nakagawa, I, S Hamada

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 296　No. 5　p. 1329-1333　2002/09　Research paper (scientific journal)

Infection and pathogenesis of a murine strain of Escherichia coli with genetically introduced Shiga toxin type I operon in conventional mice

Nakagawa, I, M Nakata, T Yamamura, S Wakisaka, S Kawabata, S Hamada

MICROBIAL PATHOGENESIS　Vol. 33　No. 2　p. 63-72　2002/08　Research paper (scientific journal)

Distribution of emm genotypes and superantigen genes of Streptococcus pyogenes isolated in Japan, 1994-9

J Murakami, S Kawabata, Y Terao, K Kikuchi, K Totsuka, A Tamaru, C Katsukawa, K Moriya, Nakagawa, I, Morisaki, I, S Hamada

EPIDEMIOLOGY AND INFECTION　Vol. 128　No. 3　p. 397-404　2002/06　Research paper (scientific journal)

Induction of septic arthritis by group A streptococcus

A. Sakurai, N. Okahashi, I. Nakagawa, S. Kawabata, T. Ooshima, S. Hamada

Jpn. J. Bacteriol. 57:　2002/04　Research paper (other academic)

RANKL expression on osteoblasts infected with group A strepcotoccus

N. Okahashi, A. Sakurai, I. Nakagawa, T. Fujiwara, S. Kawabata, A. Amano, S. Hamada

Jpn. J. Bacteriol. 57:　2002/03　Research paper (other academic)

Novel laminin-binding protein of Streptococcus pyogenes, Lbp, is involved in adhesion to epithelial cells

Y Terao, S Kawabata, E Kunitomo, Nakagawa, I, S Hamada

INFECTION AND IMMUNITY　Vol. 70　No. 2　p. 993-997　2002/02　Research paper (scientific journal)

Functional differences among FimA variants of Porphyromonas gingivalis and their effects on adhesion to and invasion of human epithelial cells

Nakagawa, I, A Amano, M Kuboniwa, T Nakamura, S Kawabata, S Hamada

INFECTION AND IMMUNITY　Vol. 70　No. 1　p. 277-285　2002/01　Research paper (scientific journal)

Administration of superantigens protects mice from lethal Listeria monocytogenes infection by enhancing cytotoxic T cells

S Okamoto, S Kawabata, Nakagawa, I, S Hamada

INFECTION AND IMMUNITY　Vol. 69　No. 11　p. 6633-6642　2001/11　Research paper (scientific journal)

Biochemical and genetic properties of Streptococcus mutans isolated from patients with bacteremia

Fujiwara T, Nakano K, Kawaguchi M, Kawabata S, Ooshima T, Sobue S, Hamada S

European Journal of Oral Sciences　2001/10　Research paper (scientific journal)

Biochemical and genetic characterization of serologically untypable Streptococcus mutans strains isolated from patients with bacteremia

T Fujiwara, K Nakano, M Kawaguchi, T Ooshima, S Sobue, S Kawabata, Nakagawa, I, S Hamada

EUROPEAN JOURNAL OF ORAL SCIENCES　Vol. 109　No. 5　p. 330-334　2001/10　Research paper (scientific journal)

Fba, a novel fibronectin-binding protein from Streptococcus pyogenes, promotes bacterial entry into epithelial cells, and the fba gene is positively transcribed under the Mga regulator

Y Terao, S Kawabata, E Kunitomo, J Murakami, Nakagawa, I, S Hamada

MOLECULAR MICROBIOLOGY　Vol. 42　No. 1　p. 75-86　2001/10　Research paper (scientific journal)

Cytochrome c-mediated caspase-9 activation triggers apoptosis in Streptococcus pyogenes-infected epithelial cells

Nakagawa, I, M Nakata, S Kawabata, S Hamada

CELLULAR MICROBIOLOGY　Vol. 3　No. 6　p. 395-405　2001/06　Research paper (scientific journal)

Systemic and mucosal immunizations with fibronectin-binding protein FBP54 induce protective immune responses against Streptococcus pyogenes challenge in mice

S Kawabata, E Kunitomo, Y Terao, Nakagawa, I, K Kikuchi, KI Totsuka, S Hamada

INFECTION AND IMMUNITY　Vol. 69　No. 2　p. 924-930　2001/02　Research paper (scientific journal)

Distribution and Molecular Characterization of Porphyromonas gingivalis Carrying a New Type of fimA Gene

Nakagawa I, Amano A, Kimura RK, Nakamura T, Kawabata S, Hamada S

Journal of Clinical Microbiology　Vol. 43　No. 3　p. 247-256　2000/05　Research paper (scientific journal)

Streptococcus pyogenesのHEp-2細胞への付着・侵入における唾液タンパクの影響

村上旬平, 川端重忠, 天野敦雄, 浜田茂幸

日本細菌学雑誌　2000/04　Research paper (other academic)

Molecular cloning, sequence and characterization of a novel streptococcal phosphoglycerate dehydrogenase gene

S Kawabata, Y Terao, S Hamada

ORAL MICROBIOLOGY AND IMMUNOLOGY　Vol. 15　No. 1　p. 58-62　2000/02　Research paper (scientific journal)

Human interleukin-12 enhances interferon-gamma-producing influenza-specific memory CD8(+) cytotoxic T lymphocytes

IN Mbawuike, K Fujihashi, S DiFabio, S Kawabata, McGhee, JR, RB Couch, H Kiyono

JOURNAL OF INFECTIOUS DISEASES　Vol. 180　No. 5　p. 1477-1486　1999/11　Research paper (scientific journal)

Targeted salivary gland immunization with plasmid DNA elicits specific salivary immunoglobulin A and G antibodies and serum immunoglobulin G antibodies in mice

S Kawabata, Y Terao, T Fujiwara, Nakagawa, I, S Hamada

INFECTION AND IMMUNITY　Vol. 67　No. 11　p. 5863-5868　1999/11　Research paper (scientific journal)

Secretion of Functional Salivary Peptide by Streptococcus gordonii which Inhibits Fimbriae-Mediated Adhesion of Porphyromonas gingivalis

Kataoka K, Amano A, Kawabata S, Nagata H, Hamada S, Shizukuishi S

Infect Immun　Vol. 67　p. 3780-3785　1999/09　Research paper (scientific journal)

Inhibitory effects of protamines on proteolytic and adhesive activities of Porphyromonas gingivalis

M Kontani, A Amano, T Nakamura, Nakagawa, I, S Kawabata, S Hamada

INFECTION AND IMMUNITY　Vol. 67　No. 9　p. 4917-4920　1999/09　Research paper (scientific journal)

Capsular hyaluronic acid of Group A Streptococci hampers their invasion into human pharyngeal epithelial cells

S Kawabata, H Kuwata, Nakagawa, I, S Morimatsu, K Sano, S Hamada

MICROBIAL PATHOGENESIS　Vol. 27　No. 2　p. 71-80　1999/08　Research paper (scientific journal)

Regulated Expression of the Shiga Toxin B Gene Induces Apoptosis in Mammalian Fibroblastic Cells

Nakagawa I, Nakata M, Kawabata S, Hamada S

Molecular Microbiology　1999/06　Research paper (scientific journal)

Mucosal Th1- versus Th2-type responses for antibody- or cell-mediated immunity to simian immunodeficiency virus in rhesus macaques

McGhee, JR, H Kiyono, M Kubota, S Kawabata, CJ Miller, T Lehner, K Imaoka, K Fujihashi

JOURNAL OF INFECTIOUS DISEASES　Vol. 179　p. S480-S484　1999/05　Research paper (scientific journal)

Molecular interactions of Porphyromonas gingivalis fimbriae with host proteins: Kinetic analyses based on surface plasmon resonance

A Amano, T Nakamura, S Kimura, Morisaki, I, Nakagawa, I, S Kawabata, S Hamada

INFECTION AND IMMUNITY　Vol. 67　No. 5　p. 2399-2405　1999/05　Research paper (scientific journal)

Molecular Biology of Cariogenic Bcateria Molecular Analysis of Virulence Traits of Mutans Streptococci and Suppression of Their Pathogenic Activites

HAMADA Shigeyuki, KAWABATA Shigetada, FUJIWARA Taku, OOSHIMA Takashi

Vol. 18　No. 1　p. 108-111　1999　Research paper (scientific journal)

Studying biofilm formation of mutans streptococci

S Kawabata, S Hamada

BIOFILMS　Vol. 310　p. 513-523　1999

う蝕病原菌の分子生物学

浜田茂幸, 川端重忠, 藤原卓, 大嶋隆

日本歯科医学会誌　1999/01　Research paper (scientific journal)

Recombinant Helicobacter pylori urease activates primary mucosal macrophages

PR Harris, PB Ernst, S Kawabata, H Kiyono, MF Graham, PD Smith

JOURNAL OF INFECTIOUS DISEASES　Vol. 178　No. 5　p. 1516-1520　1998/11　Research paper (scientific journal)

Intraepithelial lymphocytes from villus tip and crypt portions of the murine small intestine show distinct characteristics

S Kawabata, PN Boyaka, M Coste, K Fujihashi, M Yamamoto, McGhee, JR, H Kiyono

GASTROENTEROLOGY　Vol. 115　No. 4　p. 866-873　1998/10　Research paper (scientific journal)

The importance of fimbriae in the virulence and ecology of some oral bacteria

S Hamada, A Amano, S Kimura, Nakagawa, I, S Kawabata, Morisaki, I

ORAL MICROBIOLOGY AND IMMUNOLOGY　Vol. 13　No. 3　p. 129-138　1998/06

Molecular analyses of glucosyltransferase genes among strains of Streptococcus mutans

T Fujiwara, Y Terao, T Hoshino, S Kawabata, T Ooshima, S Sobue, S Kimura, S Hamada

FEMS MICROBIOLOGY LETTERS　Vol. 161　No. 2　p. 331-336　1998/04　Research paper (scientific journal)

歯科における感染症の未来像

川端重忠, 浜田茂幸

歯界展望　Vol. 91　No. 3　p. 734-743　1998/03

Targeted lymph-node immunization with whole inactivated simian immunodeficiency virus (SIV) or envelope and core subunit antigen vaccines does not reliably protect rhesus macaques from vaginal challenge with SIV(mac251)

XS Lu, H Kiyono, D Lu, S Kawabata, J Torten, S Srinivasan, PJ Dailey, McGhee, JR, T Lehner, CJ Miller

AIDS　Vol. 12　No. 1　p. 1-10　1998/01　Research paper (scientific journal)

Induction of Th2 cytokine expression for p27-specific IgA B cell responses after targeted lymph node immunization with simian immunodeficiency virus antigens in rhesus macaques

S Kawabata, CJ Miller, T Lehner, K Fujihashi, M Kubota, McGhee, JR, K Imaoka, T Hiroi, H Kiyono

JOURNAL OF INFECTIOUS DISEASES　Vol. 177　No. 1　p. 26-33　1998/01　Research paper (scientific journal)

High mucosal levels of tumor necrosis factor alpha messenger RNA in AIDS-associated cytomegalovirus-induced esophagitis

CM Wilcox, PR Harris, TK Redman, S Kawabata, T Hiroi, H Kiyono, PD Smith

GASTROENTEROLOGY　Vol. 114　No. 1　p. 77-82　1998/01　Research paper (scientific journal)

A novel alkaline phosphatase-based isolation method allows characterization of intraepithelial lymphocytes from villi tip and crypt regions of murine small intestine

S Kawabata, PN Boyaka, M Coste, K Fujihashi, S Hamada, McGhee, JR, H Kiyono

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 241　No. 3　p. 797-802　1997/12　Research paper (scientific journal)

Nucleotide sequence and molecular characterization of a gene encoding GTP-binding protein from Streptococcus gordonii

S Kawabata, Y Terao, T Andoh, S Hamada

FEMS MICROBIOLOGY LETTERS　Vol. 156　No. 2　p. 211-216　1997/11　Research paper (scientific journal)

Oral immunization with simian immunodeficiency virus p55(gag) and cholera toxin elicits both mucosal IgA and systemic IgG immune responses in nonhuman primates

M Kubota, CJ Miller, K Imaoka, S Kawabata, K Fujihashi, McGhee, JR, H Kiyono

JOURNAL OF IMMUNOLOGY　Vol. 158　No. 11　p. 5321-5329　1997/06　Research paper (scientific journal)

Helicobacter pylori 感染症

川端重忠

歯界展望　1997/03

Modification of sucrose dependent cell adherence by deletion and reintroduction of the gtf genes in Streptococcus mutans

M Tamesada, S Kawabata, Z Bian, T Fujiwara, S Kimura, S Hamada

STREPTOCOCCI AND THE HOST　Vol. 418　p. 665-668　1997　Research paper (scientific journal)

Functional gamma delta T-lymphocyte defect associated with human immunodeficiency virus infections

M Wallace, AM Scharko, CD Pauza, P Fisch, K Imaoka, S Kawabata, K Fujihashi, H Kiyono, Y Tanaka, BR Bloom, M Malkovsky

MOLECULAR MEDICINE　Vol. 3　No. 1　p. 60-71　1997/01　Research paper (scientific journal)

Protective and Pathogenic Role of Mouse Mucosal T Cells

Takahashi I, Kawabata S, Hamada S, Kiyono H

1996/05

Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor-positive intraepithelial lymphocytes

K Fujihashi, S Kawabata, T Hiroi, M Yamamoto, McGhee, JR, SI Nishikawa, H Kiyono

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 93　No. 8　p. 3613-3618　1996/04　Research paper (scientific journal)

Deletion and reintroduction of glucosyltransferase genes of Streptococcus mutans and role of their gene products in sucrose dependent cellular adherence

T Fujiwara, M Tamesada, ZA Bian, S Kawabata, S Kimura, S Hamada

MICROBIAL PATHOGENESIS　Vol. 20　No. 4　p. 225-233　1996/04　Research paper (scientific journal)

Intraepithelial gamma delta T cell and epithelial cell interactions in the mucosal immune system

H Kiyono, K Fujihashi, M Yamamoto, T Hiroi, M Coste, S Kawabata, P Boyaka, McGhee, JR

ESSENTIALS OF MUCOSAL IMMUNOLOGY　p. 195-204　1996　Research paper (international conference proceedings)

The common mucosal immune system for the reproductive tract: Basic principles applied toward an AIDS vaccine

H Kiyono, CJ Miller, YC Lu, T Lehner, M Cranage, YT Huang, S Kawabata, M Marthas, B Roberts, JG Nedrud, ME Lamm, L Bergmeier, R Brookes, L Tao, McGhee, JR

ADVANCED DRUG DELIVERY REVIEWS　Vol. 18　No. 1　p. 23-52　1995/12

Molecular and cellular regulation of intestinal immune responses

Kawabata S, Kiyono H

1995/03

INHIBITORY EFFECT OF OOLONG TEA POLYPHENOLS ON GLUCOSYLTRANSFERASES OF MUTANS STREPTOCOCCI

K NAKAHARA, S KAWABATA, H ONO, K OGURA, T TANAKA, T OOSHIMA, S HAMADA

APPLIED AND ENVIRONMENTAL MICROBIOLOGY　Vol. 59　No. 4　p. 968-973　1993/04　Research paper (scientific journal)

Oolong tea polyphenols inhibit experimental dental caries in spf rats infected with mutans streptococci

T. Ooshima, T. Minami, W. Aono, A. Izumitani, S. Sobue, T. Fujiwara, S. Kawabata, S. Hamada

Caries Research　Vol. 27　No. 2　p. 124-129　1993　Research paper (scientific journal)

EFFECTS OF SELECTED SURFACTANTS ON PURIFIED GLUCOSYLTRANSFERASES FROM MUTANS STREPTOCOCCI AND CELLULAR ADHERENCE TO SMOOTH SURFACES

S KAWABATA, M TORII, T MINAMI, T FUJIWARA, S HAMADA

JOURNAL OF MEDICAL MICROBIOLOGY　Vol. 38　No. 1　p. 54-60　1993/01　Research paper (scientific journal)

MOLECULAR CHARACTERIZATION AND EXPRESSION OF THE CELL-ASSOCIATED GLUCOSYLTRANSFERASE GENE FROM STREPTOCOCCUS-MUTANS

T FUJIWARA, S KAWABATA, S HAMADA

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 187　No. 3　p. 1432-1438　1992/09　Research paper (scientific journal)

ORAL PASSIVE-IMMUNIZATION AGAINST DENTAL-CARIES IN RATS BY USE OF HEN EGG-YOLK ANTIBODIES SPECIFIC FOR CELL-ASSOCIATED GLUCOSYLTRANSFERASE OF STREPTOCOCCUS-MUTANS

S HAMADA, T HORIKOSHI, T MINAMI, S KAWABATA, J HIRAOKA, T FUJIWARA, T OOSHIMA

INFECTION AND IMMUNITY　Vol. 59　No. 11　p. 4161-4167　1991/11　Research paper (scientific journal)

イソマルトオリゴ糖のう蝕誘発能

南貴洋, 三木忠浩, 藤原卓, 川端重忠, 泉谷明, 大嶋隆, 祖父江鎮雄, 浜田茂幸

小児歯科学雑誌　1989/04　Research paper (scientific journal)