β-aminoisobutyric acid protects against vascular inflammation through PGC-1β-induced antioxidative properties

Miho Sawada, Hiroyasu Yamamoto, Ayako Ogasahara, Yuya Tanaka, Shinji Kihara

Biochemical and Biophysical Research Communications　Vol. 516　No. 3　p. 963-968　2019/08/27　Research paper (scientific journal)

Juvenile-onset systemic lupus erythematosus with severe hypertriglyceridemia induced by anti-apolipoprotein C-II antibody.

Inoue M, Kawamura M, Yamamoto H, Takahashi T, Kihara S

Pediatrics International　Vol. 61　No. 2　p. 201-203　2019/02　Research paper (scientific journal)

Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017.

Makoto Kinoshita, Koutaro Yokote, Hidenori Arai, Mami Iida, Yasushi Ishigaki, Shun Ishibashi, Seiji Umemoto, Genshi Egusa, Hirotoshi Ohmura, Tomonori Okamura, Shinji Kihara, Shinji Koba, Isao Saito, Tetsuo Shoji, Hiroyuki Daida, Kazuhisa Tsukamoto, Juno Deguchi, Seitaro Dohi, Kazushige Dobashi, Hirotoshi Hamaguchi, Masumi Hara, Takafumi Hiro, Sadatoshi Biro, Yoshio Fujioka, Chizuko Maruyama, Yoshihiro Miyamoto, Yoshitaka Murakami, Masayuki Yokode, Hiroshi Yoshida, Hiromi Rakugi, Akihiko Wakatsuki, Shizuya Yamashita

Journal of atherosclerosis and thrombosis　Vol. 25　No. 9　p. 846-984　2018/09/01　Research paper (scientific journal)

Mechanistic insight into the suppression of microglial ros production by voltage-gated proton channels (VSOP/Hv1)

Takafumi Kawai, Shoki Tatsumi, Shinji Kihara, Kenji Sakimura, Yasushi Okamura

Channels　Vol. 12　No. 1　p. 1-8　2018/01/01　Research paper (scientific journal)

Effects of a dipeptidyl peptidase 4 inhibitor sitagliptin on glycemic control and lipoprotein metabolism in patients with type 2 diabetes mellitus (GLORIA trial)

Daisaku Masuda, Takuya Kobayashi, Masami Sairyou, Hiroyuki Hanada, Tohru Ohama, Masahiro Koseki, Makoto Nishida, Norikazu Maeda, Shinji Kihara, Tatsuya Minami, Koji Yanagi, Yasushi Sakata, Shizuya Yamashita

Journal of Atherosclerosis and Thrombosis　Vol. 25　No. 6　p. 512-520　2018　Research paper (scientific journal)

Achilles Tendon Ultrasonography for Diagnosis of Familial Hypercholesterolemia Among Japanese Subjects

Masahito Michikura, Masatsune Ogura, Masahiro Yamamoto, Masahiko Sekimoto, Chizuru Fuke, Mika Hori, Koji Arai, Shinji Kihara, Kiminori Hosoda, Koji Yanagi, Mariko Harada-Shiba

CIRCULATION JOURNAL　Vol. 81　No. 12　p. 1879-1885　2017/12　Research paper (scientific journal)

Cystatin C–adiponectin complex in plasma associates with coronary plaque instability

Akane Matsumoto, Hiroyasu Yamamoto, Tetsuro Matsuoka, Kento Kayama, Sumire Onishi, Natsumi Matsuo, Shinji Kihara

Journal of Atherosclerosis and Thrombosis　Vol. 24　No. 9　p. 970-979　2017　Research paper (scientific journal)

Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs.

Mikio Watanabe, Chika Honda, Yoshinori Iwatani, Shiro Yorifuji, Hiroyasu Iso, Kei Kamide, Jun Hatazawa, Shinji Kihara, Norio Sakai, Hiroko Watanabe, Kiyoko Makimoto, Mikio Watanabe, Chika Honda, Yoshinori Iwatani

BMC medical genomics　Vol. 9　No. 1　p. 55-55　2016/08/26　Research paper (scientific journal)

Marked elevation of serum M2BP-adiponectin complex in men with coronary artery disease.

Niinaga R, Yamamoto H, Yoshii M, Uekita H, Yamane N, Kochi I, Matsumoto A, Matsuoka T, Kihara S

Atherosclerosis　2016/08　Research paper (scientific journal)

Omentin attenuates atherosclerotic lesion formation in apolipoprotein E-deficient mice

Mizuho Hiramatsu-Ito, Rei Shibata, Koji Ohashi, Yusuke Uemura, Noriyoshi Kanemura, Takahiro Kambara, Takashi Enomoto, Daisuke Yuasa, Kazuhiro Matsuo, Masanori Ito, Satoko Hayakawa, Hayato Ogawa, Naoya Otaka, Shinji Kihara, Toyoaki Murohara, Noriyuki Ouchi

CARDIOVASCULAR RESEARCH　Vol. 110　No. 1　p. 107-117　2016/05　Research paper (scientific journal)

E-selectin ligand-1 (ESL-1) is a novel adiponectin binding protein on cell adhesion

Hiroyasu Yamamoto, Nana Kuroda, Hiromi Uekita, Ikoi Kochi, Akane Matsumoto, Ryu Niinaga, Tohru Funahashi, Iichiro Shimomura, Shinji Kihara

Biochemical and Biophysical Research Communications　Vol. 470　No. 2　p. 425-430　2016/02/05　Research paper (scientific journal)

Omentin functions to attenuate cardiac hypertrophic response

Kazuhiro Matsuo, Rei Shibata, Koji Ohashi, Takahiro Kambara, Yusuke Uemura, Mizuho Hiramatsu-Ito, Takashi Enomoto, Daisuke Yuasa, Yusuke Joki, Masanori Ito, Satoko Hayakawa, Hayato Ogawa, Shinji Kihara, Toyoaki Murohara, Noriyuki Ouchi

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY　Vol. 79　p. 195-202　2015/02　Research paper (scientific journal)

Adiponectin deficiency exacerbates age-related hearing impairment.

Tanigawa T, Shibata R, Ouchi N, Kondo K, Ishii M, Katahira N, Kambara T, Inoue Y, Takahashi R, Ikeda N, Kihara S, Ueda H, Murohara T

Cell Death Dis.　2014/04　Research paper (scientific journal)

Statements

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote, Japan Atherosclerosis Society Committee for Epidemiology and Clinical Management of Atherosclerosis

Journal of atherosclerosis and thrombosis　Vol. 21　No. 4　p. 299-303　2014　Research paper (scientific journal)

Women

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

Journal of Atherosclerosis and Thrombosis　Vol. 21　No. 4　p. 291-295　2014　Research paper (scientific journal)

Diagnosis of atherosclerosis.

Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K, Japan Atherosclerosis Society Committee for Epidemiology, Clinical Management, of Atherosclerosis

Journal of atherosclerosis and thrombosis　Vol. 21　No. 4　p. 296-298　2014

Chronic kidney disease

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

Journal of Atherosclerosis and Thrombosis　Vol. 21　No. 3　p. 173-174　2014　Research paper (scientific journal)

Diagnosis of Atherosclerosis Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 4　p. 296-303　2014　Research paper (scientific journal)

Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 1　p. 1-5　2014

Diabetes Mellitus

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 2　p. 93-98　2014　Research paper (scientific journal)

Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 3　p. 175-179　2014

Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 3　p. 180-185　2014

Women Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 4　p. 291-295　2014　Research paper (scientific journal)

Familial Hypercholesterolemia Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan 2012 Version (Vol 21, pg 6, 2014)

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 3　p. 289-289　2014

Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 3　p. 173-174　2014

Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote, Mariko Harada-Shiba, Hidenori Arai, Hideaki Bujo, Atsushi Nohara, Takao Ohta, Shinichi Oikawa, Tomoo Okada, Tomonori Okamura, Akihiko Wakatsuki, Koutaro Yokote, Shizuya Yamashita, Mariko Harada-Shiba, Hidenori Arai, Hideaki Bujo, Takao Ohta, Shinichi Oikawa, Shizuya Yamashita, Shun Ishibashi

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 1　p. 6-10　2014

Coronary Artery Disease

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 21　No. 2　p. 86-92　2014　Research paper (scientific journal)

Cerebrovascular diseases

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

Journal of Atherosclerosis and Thrombosis　Vol. 21　No. 3　p. 175-179　2014　Research paper (scientific journal)

Metabolic syndrome.

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

Journal of Atherosclerosis and Thrombosis　Vol. 21　No. 1　p. 1-5　2014　Research paper (scientific journal)

Accumulation of adiponectin in inflamed adipose tissues of obese mice

Hideaki Nakatsuji, Ken Kishida, Ryohei Sekimoto, Noriyuki Komura, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura

Metabolism: Clinical and Experimental　Vol. 63　No. 4　p. 542-553　2014　Research paper (scientific journal)

Fat accumulation and obesity-related cardiovascular risk factors in middle-aged Japanese men and women

Miwa Ryo, Tohru Funahashi, Tadashi Nakamura, Shinji Kihara, Kazuaki Kotani, Katsuto Tokunaga, Yuji Matsuzawa, Iichiro Shimomura

Internal Medicine　Vol. 53　No. 4　p. 299-305　2014　Research paper (scientific journal)

Autoimmune severe hypertriglyceridemia induced by anti-apolipoprotein C-II antibody

Hiroyasu Yamamoto, Minoru Tanaka, Satomi Yoshiga, Tohru Funahashi, Iichiro Shimomura, Shinji Kihara

Journal of Clinical Endocrinology and Metabolism　Vol. 99　No. 5　p. 1525-1530　2014　Research paper (scientific journal)

Adiponectin-Mediated Modulation of Lymphatic Vessel Formation and Lymphedema

Yuuki Shimizu, Rei Shibata, Masakazu Ishii, Koji Ohashi, Takahiro Kambara, Yusuke Uemura, Daisuke Yuasa, Yoshiyuki Kataoka, Shinji Kihara, Toyoaki Murohara, Noriyuki Ouchi

JOURNAL OF THE AMERICAN HEART ASSOCIATION　Vol. 2　No. 5　2013/09　Research paper (scientific journal)

Diagnostic criteria for dyslipidemia.

Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, Egusa G, Hiro T, Hirobe K, Iida M, Kihara S, Kinoshita M, Maruyama C, Ohta T, Okamura T, Yamashita S, Yokode M, Yokote K

Journal of atherosclerosis and thrombosis　Vol. 20　No. 8　p. 655-660　2013/08　Research paper (scientific journal)

Adiponectin Protein Exists in Aortic Endothelial Cells

Noriyuki Komura, Norikazu Maeda, Takuya Mori, Shinji Kihara, Hideaki Nakatsuji, Ayumu Hirata, Yoshihiro Tochino, Tohru Funahashi, Iichiro Shimomura

PLOS ONE　Vol. 8　No. 8　2013/08　Research paper (scientific journal)

Adiponectin Regulates Vascular Endothelial Growth Factor-C Expression in Macrophages via Syk-ERK Pathway

Di Hu, Atsunori Fukuhara, Yugo Miyata, Chieko Yokoyama, Michio Otsuki, Shinji Kihara, Iichiro Shimomura

PLoS ONE　Vol. 8　No. 2　2013/02/12　Research paper (scientific journal)

Adiponectin inhibits macrophage tissue factor, a key trigger of thrombosis in disrupted atherosclerotic plaques

Yoshihisa Okamoto, So Ishii, Kevin Croce, Harumi Katsumata, Makoto Fukushima, Shinji Kihara, Peter Libby, Shiro Minami

ATHEROSCLEROSIS　Vol. 226　No. 2　p. 373-377　2013/02　Research paper (scientific journal)

Comprehensive risk management for the prevention of cardiovascular disease

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

Journal of Atherosclerosis and Thrombosis　Vol. 20　No. 7　p. 603-615　2013

Other High-Risk Conditions Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 20　No. 11　p. 785-789　2013　Research paper (scientific journal)

Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan - 2012 Version

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 20　No. 6　p. 517-523　2013　Research paper (scientific journal)

Cardiovascular Disease Risk Factors Other than Dyslipidemia

Tamio Teramoto, Jun Sasaki, Shun Ishibashi, Sadatoshi Birou, Hiroyuki Daida, Seitaro Dohi, Genshi Egusa, Takafumi Hiro, Kazuhiko Hirobe, Mami Iida, Shinji Kihara, Makoto Kinoshita, Chizuko Maruyama, Takao Ohta, Tomonori Okamura, Shizuya Yamashita, Masayuki Yokode, Koutaro Yokote

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 20　No. 10　p. 733-742　2013　Research paper (scientific journal)

Treatment A) Lifestyle Modification Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 20　No. 12　p. 835-849　2013　Research paper (scientific journal)

Treatment B) Drug Therapy Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan-2012 Version

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 20　No. 12　p. 850-860　2013　Research paper (scientific journal)

Absolute risk of cardiovascular disease and lipid management targets

Teramoto Tamio, Sasaki Jun, Ishibashi Shun, Birou Sadatoshi, Daida Hiroyuki, Dohi Seitaro, Egusa Genshi, Hiro Takafumi, Hirobe Kazuhiko, Iida Mami, Kihara Shinji, Kinoshita Makoto, Maruyama Chizuko, Ohta Takao, Okamura Tomonori, Yamashita Shizuya, Yokode Masayuki, Yokote Koutaro

Journal of Atherosclerosis and Thrombosis　Vol. 20　No. 9　p. 689-697　2013　Research paper (scientific journal)

Novel Combined GPIHBP1 Mutations in a Patient with Hypertriglyceridemia Associated with CAD

Hiroyasu Yamamoto, Misa Onishi, Naoko Miyamoto, Ryosuke Oki, Hiroyasu Ueda, Masato Ishigami, Hisatoyo Hiraoka, Yuji Matsuzawa, Shinji Kihara

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 20　No. 10　p. 777-784　2013　Research paper (scientific journal)

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. 1999.

Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y

Biochemical and biophysical research communications　Vol. 425　No. 3　p. 560-564　2012/08

Omentin as a novel biomarker of metabolic risk factors

Rei Shibata, Noriyuki Ouchi, Ryotaro Takahashi, Yuya Terakura, Koji Ohashi, Nobuo Ikeda, Akiko Higuchi, Hiroko Terasaki, Shinji Kihara, Toyoaki Murohara

DIABETOLOGY & METABOLIC SYNDROME　Vol. 4　No. 1　2012/06　Research paper (scientific journal)

Protective role of adiponectin against ethanol-induced gastric injury in mice.

Shunsuke Yamamoto, Kenji Watabe, Hiroshi Araki, Yoshihiro Kamada, Motohiko Kato, Takashi Kizu, Shinichi Kiso, Shusaku Tsutsui, Masahiko Tsujii, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura, Norio Hayashi, Tetsuo Takehara

Am J Physiol Gastrointest Liver Physiol.　Vol. 302　No. 8　p. G773-G780　2012/04　Research paper (scientific journal)

Fat-derived Factor Omentin Stimulates Endothelial Cell Function and Ischemia-induced Revascularization via Endothelial Nitric Oxide Synthase-dependent Mechanism

Sonomi Maruyama, Rei Shibata, Ryosuke Kikuchi, Yasuhiro Izumiya, Taku Rokutanda, Satoshi Araki, Yoshiyuki Kataoka, Koji Ohashi, Hiroyuki Daida, Shinji Kihara, Hisao Ogawa, Toyoaki Murohara, Noriyuki Ouchi

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 287　No. 1　p. 408-417　2012/01　Research paper (scientific journal)

Circulating omentin is associated with coronary artery disease in men

Rei Shibata, Noriyuki Ouchi, Ryosuke Kikuchi, Ryotaro Takahashi, Kyosuke Takeshita, Yoshiyuki Kataoka, Koji Ohashi, Nobuo Ikeda, Shinji Kihara, Toyoaki Murohara

ATHEROSCLEROSIS　Vol. 219　No. 2　p. 811-814　2011/12　Research paper (scientific journal)

Dynamic Changes of Adiponectin and S100A8 Levels by the Selective Peroxisome Proliferator-Activated Receptor-gamma Agonist Rivoglitazone

Aki Hiuge-Shimizu, Norikazu Maeda, Ayumu Hirata, Hideaki Nakatsuji, Kouichi Nakamura, Akira Okuno, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY　Vol. 31　No. 4　p. 792-799　2011/11　Research paper (scientific journal)

Association of low serum adiponectin levels with erosive esophagitis in men: an analysis of 2405 subjects undergoing physical check-ups

Motohiko Kato, Kenji Watabe, Toshimitsu Hamasaki, Miyuki Umeda, Aiko Furubayashi, Kazuo Kinoshita, Osamu Kishida, Takashi Fujimoto, Akira Yamada, Yoshifumi Tsukamoto, Shunsuke Yamamoto, Yoshihiro Kamada, Yuichi Yoshida, Shinichi Kiso, Shusaku Tsutsui, Shinji Kihara, Norio Hayashi, Yuji Matsuzawa

JOURNAL OF GASTROENTEROLOGY　Vol. 46　No. 12　p. 1361-1367　2011/08　Research paper (scientific journal)

Association of a fat-derived plasma protein omentin with carotid artery intima-media thickness in apparently healthy men

Rei Shibata, Ryotaro Takahashi, Yoshiyuki Kataoka, Koji Ohashi, Nobuo Ikeda, Shinji Kihara, Toyoaki Murohara, Noriyuki Ouchi

HYPERTENSION RESEARCH　Vol. 34　No. 12　p. 1309-1312　2011/08　Research paper (scientific journal)

Lower Serum Level of Adiponectin Is Associated with Increased Risk of Endoscopic Erosive Gastritis

Shunsuke Yamamoto, Kenji Watabe, Shusaku Tsutsui, Shinichi Kiso, Toshimitsu Hamasaki, Motohiko Kato, Yoshihiro Kamada, Yuichi Yoshida, Shinji Kihara, Miyuki Umeda, Aiko Furubayashi, Kazuo Kinoshita, Osamu Kishida, Takashi Fujimoto, Akira Yamada, Yoshifumi Tsukamoto, Norio Hayashi, Yuji Matsuzawa

DIGESTIVE DISEASES AND SCIENCES　Vol. 56　No. 8　p. 2354-2360　2011/08　Research paper (scientific journal)

腎不全におけるアディポネクチン濃度上昇と機能障害機序

小村 徳幸, 木原 進士, 前田 法一, 船橋 徹, 下村 伊一郎

日本内分泌学会雑誌　Vol. 87　No. 1　p. 356-356　2011/04

Nocturnal Falls of Adiponectin Levels in Sleep Apnea with Abdominal Obesity and Impact of Hypoxia-Induced Dysregulated Adiponectin Production in Obese Murine Mesenteric Adipose Tissue

Yasuhiko Nakagawa, Ken Kishida, Shinji Kihara, Ryoko Yoshida, Tohru Funahashi, Iichiro Shimomura

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS　Vol. 18　No. 3　p. 240-247　2011/03　Research paper (scientific journal)

A Case of Adolescent Hyperlipoproteinemia with Xanthoma and Acute Pancreatitis, Associated with Decreased Activities of Lipoprotein Lipase and Hepatic Triglyceride Lipase

Koichi Fujita, Norikazu Maeda, Junji Kozawa, Kakeyoshi Murano, Kohei Okita, Hiromi Iwahashi, Shinji Kihara, Masato Ishigami, Motoko Omura, Tadashi Nakamura, Kohji Shirai, Taku Yamamura, Tohru Funahashi, Iichiro Shimomura

INTERNAL MEDICINE　Vol. 49　No. 22　p. 2467-2472　2010/11　Research paper (scientific journal)

Lack of adiponectin promotes formation of cholesterol gallstones in mice

Hideharu Ogiyama, Yoshihiro Kamada, Shinichi Kiso, Hiroshi Araki, Takuya Yamada, Tamao Nishihara, Kenji Watabe, Yoshihiro Tochino, Shinji Kihara, Tohru Funahashi, Keishi Kanno, Iichiro Shimomura, Shusaku Tsutsui, Susumu Tazuma, Norio Hayashi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 399　No. 3　p. 352-358　2010/08　Research paper (scientific journal)

Adiponectin deficiency enhanced the severity of cerulein-induced chronic pancreatitis in mice.

Yamada T, Araki H, Watabe K, Kamada Y, Kiso S, Ogiyama H, Nishihara T, Kihara S, Funahashi T, Shimomura I, Tsutsui S, Hayashi N

J Gastroenterol.　Vol. 45　No. 7　p. 742-749　2010/07　Research paper (scientific journal)

Increment and impairment of adiponectin in renal failure

Noriyuki Komura, Shinji Kihara, Mina Sonoda, Norikazu Maeda, Yoshihiro Tochino, Tohru Funahashi, Iichiro Shimomura

CARDIOVASCULAR RESEARCH　Vol. 86　No. 3　p. 471-477　2010/06　Research paper (scientific journal)

Determinants of Adiponectin Levels in Patients With Chronic Systolic Heart Failure

Andreia Biolo, Rei Shibata, Noriyuki Ouchi, Shinji Kihara, Mina Sonoda, Kenneth Walsh, Flora Sam

AMERICAN JOURNAL OF CARDIOLOGY　Vol. 105　No. 8　p. 1147-1152　2010/04　Research paper (scientific journal)

インスリン抵抗性における脂肪組織ミネラルコルチコイド受容体の意義

平田 歩, 前田 法一, 日生下 亜紀, 火伏 俊之, 藤田 幸一, 岡田 拓也, 木原 進士, 船橋 徹, 下村 伊一郎

日本内分泌学会雑誌　Vol. 86　No. 1　p. 139-139　2010/03

Reciprocal regulation of natriuretic peptide receptors by insulin in adipose cells

Hideaki Nakatsuji, Norikazu Maeda, Toshiyuki Hibuse, Aki Hiuge, Ayumu Hirata, Yohei Kuroda, Ken Kishida, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 392　No. 1　p. 100-105　2010/01　Research paper (scientific journal)

Insulin-mediated Regulation of Decidual Protein Induced by Progesterone (DEPP) in Adipose Tissue and Liver

Y. Kuroda, H. Kuriyama, S. Kihara, K. Kishida, N. Maeda, T. Hibuse, H. Nishizawa, M. Matsuda, T. Funahashi, I. Shimomura

HORMONE AND METABOLIC RESEARCH　Vol. 42　No. 3　p. 173-177　2009/11　Research paper (scientific journal)

Characteristics of sleep-disordered breathing in Japanese patients with type 2 diabetes mellitus.

Kashine S, Kishida K, Funahashi T, Nakagawa Y, Otuki M, Okita K, Iwahashi H, Kihara S, Nakamura T, Matsuzawa Y, Shimomura I

Metabolism　Vol. 59　No. 5　p. 690-696　2009/11　Research paper (scientific journal)

Adiponectin Deficiency Increases Allergic Airway Inflammation and Pulmonary Vascular Remodeling

Benjamin D. Medoff, Yoshihisa Okamoto, Patricio Leyton, Meiqian Weng, Barry P. Sandall, Michael J. Raher, Shinji Kihara, Kenneth D. Bloch, Peter Libby, Andrew D. Luster

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY　Vol. 41　No. 4　p. 397-406　2009/10　Research paper (scientific journal)

Adiponectin Inhibits Allograft Rejection in Murine Cardiac Transplantation

Yoshihisa Okamoto, Thomas Christen, Koichi Shimizu, Kenichi Asano, Shinji Kihara, Richard N. Mitchell, Peter Libby

TRANSPLANTATION　Vol. 88　No. 7　p. 879-883　2009/10　Research paper (scientific journal)

Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice

Ayumu Hirata, Norikazu Maeda, Aki Hiuge, Toshiyuki Hibuse, Koichi Fujita, Takuya Okada, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura

CARDIOVASCULAR RESEARCH　Vol. 84　No. 1　p. 164-172　2009/10　Research paper (scientific journal)

ADIPONECTIN PREVENTS PROGRESSION OF NONALCOHOLIC STEATOHEPATITIS IN MICE BY REGULATING OXIDATIVE STRESS AND KUPFFER CELL PHENOTYPE POLARIZATION

Juichi Fukushima, Yoshihiro Kamada, Hitoshi Matsumoto, Yuichi Yoshida, Hisao Ezaki, Takayo Takemura, Mina Hamano, Shinichi Kiso, Norikazu Maeda, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura, Norio Hayashi

HEPATOLOGY　Vol. 50　No. 4　p. 1180A-1180A　2009/10　Research paper (scientific journal)

肥満・インスリン抵抗性における脂肪細胞ミネラルコルチコイド受容体の病態的意義の解明

平田 歩, 前田 法一, 日生下 亜紀, 火伏 俊之, 藤田 幸一, 岡田 拓也, 木原 進士, 船橋 徹, 下村 伊一郎

肥満研究　Vol. 15　No. Suppl.　p. 249-249　2009/09

Periadventitial Adipose Tissue Plays a Critical Role in Vascular Remodeling

Minoru Takaoka, Daisuke Nagata, Shinji Kihara, Iichiro Shimomura, Yu Kimura, Yasuhiko Tabata, Yoshihiko Saito, Ryozo Nagai, Masataka Sata

CIRCULATION RESEARCH　Vol. 105　No. 9　p. 906-U185　2009/09　Research paper (scientific journal)

Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization

Juichi Fukushima, Yoshihiro Kamada, Hitoshi Matsumoto, Yuichi Yoshida, Hisao Ezaki, Takayo Takemura, Yukiko Saji, Takumi Igura, Shusaku Tsutsui, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura, Shinji Tamura, Shinichi Kiso, Norio Hayashi

HEPATOLOGY RESEARCH　Vol. 39　No. 7　p. 724-738　2009/07　Research paper (scientific journal)

Adiponectin Promotes Revascularization of Ischemic Muscle through a Cyclooxygenase 2-Dependent Mechanism

Koji Ohashi, Noriyuki Ouchi, Kaori Sato, Akiko Higuchi, Tomo-o Ishikawa, Harvey R. Herschman, Shinji Kihara, Kenneth Walsh

MOLECULAR AND CELLULAR BIOLOGY　Vol. 29　No. 13　p. 3487-3499　2009/07　Research paper (scientific journal)

Adiponectin Suppresses Pathological Microvessel Formation in Retina Through Modulation of Tumor Necrosis Factor-alpha Expression

Akiko Higuchi, Koji Ohashi, Shinji Kihara, Kenneth Walsh, Noriyuki Ouchi

CIRCULATION RESEARCH　Vol. 104　No. 9　p. 1058-1065　2009/05　Research paper (scientific journal)

心臓におけるグリセロールチャネルの意義

火伏 俊之, 前田 法一, 中辻 秀朗, 藤田 幸一, 日生下 亜紀, 岸田 堅, 木原 進士, 船橋 徹, 下村 伊一郎

日本内分泌学会雑誌　Vol. 85　No. 1　p. 284-284　2009/04

Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling

Yasuhiko Nakagawa, Ken Kishida, Shinji Kihara, Tohru Funahashi, Iichiro Shimomura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 382　No. 1　p. 183-188　2009/04　Research paper (scientific journal)

Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice

Kosuke Ebina, Kazuya Oshima, Morihiro Matsuda, Atsunori Fukuhara, Kazuhisa Maeda, Shinji Kihara, Jun Hashimoto, Takahiro Ochi, Nirmal K. Banda, Hideki Yoshikawa, Iichiro Shimomura

Biochemical and Biophysical Research Communications　Vol. 378　No. 2　p. 186-191　2009/01/09　Research paper (scientific journal)

Human genetic mutations and polymorphisms of adipocytokines relating to obesity

Aki Hiuge, Shinji Kihara

Nippon rinsho. Japanese journal of clinical medicine　Vol. 67　No. 2　p. 266-269　2009　Research paper (scientific journal)

Erratum: Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men (Internal Medicine (2008) vol. 47 (13) 1175-1180))

Sachiko Tamba, Hitoshi Nizhizawa, Tohru Funahashi, Yukiyoshi Okauchi, Tomoko Ogawa, Midori Noguchi, Koichi Fujita, Miwa Ryo, Shinji Kihara, Hiromi Iwahashi, Kazuya Yamagata, Tadashi Nakamura, Iichiro Shimomura, Yuji Matsuzawa

Internal Medicine　Vol. 48　No. 16　2009　Research paper (scientific journal)

Delayed liver regeneration after partial hepatectomy in adiponectin knockout mice

Ezaki H, Yoshida Y, Saji Y, Takemura T, Fukushima J, Matsumoto H, Kamada Y, Wada A, Igura T, Kihara S, Funahashi T, Shimomura I, Tamura S, Kiso S, Hayashi N

Biochemical and Biophysical Research Communications　Vol. 378　No. 1　p. 68-72　2009/01　Research paper (scientific journal)

Adiponectin deficiency enhances colorectal carcinogenesis and liver tumor formation induced by azoxymethane in mice

Tamao Nishihara, Miyako Baba, Morihiro Matsuda, Masahiro Inoue, Yasuko Nishizawa, Atsunori Fukuhara, Hiroshi Araki, Shinji Kihara, Tohru Funahashi, Shinji Tamura, Norio Hayashi, Hiroyasu Iishi, Iichiro Shimomura

WORLD JOURNAL OF GASTROENTEROLOGY　Vol. 14　No. 42　p. 6473-6480　2008/11　Research paper (scientific journal)

Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages

Kazumi Tsubakio-Yamamoto, Fumihiko Matsuura, Masahiro Koseki, Hiroyuki Oku, Jose C. Sandoval, Miwako Inagaki, Kazuhiro Nakatani, Hajime Nakaoka, Ryota Kawase, Miyako Yuasa-Kawase, Daisaku Masuda, Tohru Ohama, Norikazu Maeda, Yumiko Nakagawa-Toyama, Masato Ishigami, Makoto Nishida, Shinji Kihara, Iichiro Shimomura, Shizuya Yamashita

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 375　No. 3　p. 390-394　2008/10　Research paper (scientific journal)

Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet

H. Araki, T. Nishihara, M. Matsuda, A. Fukuhara, S. Kihara, T. Funahashi, T. R. Kataoka, Y. Kamada, T. Kiyohara, S. Tamura, N. Hayashi, I. Shimomura

GUT　Vol. 57　No. 10　p. 1431-1440　2008/10　Research paper (scientific journal)

Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction

Rei Shibata, Yasushi Numaguchi, Kunihiro Matsushita, Takahito Sone, Ryuji Kubota, Taiki Ohashi, Masakazu Ishii, Shinji Kihara, Kenneth Walsh, Noriyuki Ouchi, Toyoaki Murohara

AMERICAN JOURNAL OF CARDIOLOGY　Vol. 101　No. 12　p. 1712-1715　2008/07　Research paper (scientific journal)

Adiponectin promotes endothelial progenitor cell number and function.

Shibata R, Skurk C, Ouchi N, Galasso G, Kondo K, Ohashi T, Shimano M, Kihara S, Murohara T, Walsh K

FEBS Lett.　Vol. 582　No. 11　p. 1607-1612　2008/05　Research paper (scientific journal)

Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha.

Fujita K, Maeda N, Sonoda M, Ohashi K, Hibuse T, Nishizawa H, Nishida M, Hiuge A, Kurata A, Kihara S, Shimomura I, Funahashi T

Arterioscler Thromb Vasc Biol.　Vol. 28　No. 5　p. 863-870　2008/05　Research paper (scientific journal)

Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes.

Ikeda Y, Ohashi K, Shibata R, Pimentel DR, Kihara S, Ouchi N, Walsh K

FEBS Lett.　Vol. 582　No. 7　p. 1147-1150　2008/04　Research paper (scientific journal)

URB is abundantly expressed in adipose tissuenand dysregulated in obesity.

Okada T, Nishizawa H, Kurata A, Tamba S, Sonoda M, Yasui A, Kuroda Y, Hibuse T, Maeda N, Kihara S, Hadama T, Tobita K, Akamatsu S, Maeda K, Shimomura I, Funahashi T

Biochem Biophys Res Commun　Vol. 367　No. 2　p. 370-376　2008/03　Research paper (scientific journal)

Adiponectin inhibits the production of CXC receptor 3 chemokine ligands in macrophages and reduces T-lymphocyte recruitment in atherogenesis

Yoshihisa Okamoto, Eduardo J. Folco, Manabu Minami, A. K. Wara, Mark W. Feinberg, Galina K. Sukhova, Richard A. Colvin, Shinji Kihara, Tohru Funahashi, Andrew D. Luster, Peter Libby

Circulation Research　Vol. 102　No. 2　p. 218-225　2008/02　Research paper (scientific journal)

Association of adiponectin and resistin with cardiovascular events in Korean patients with type 2 diabetes: the Korean atherosclerosis study (KAS): a 42-month prospective study.

Lim S, Koo BK, Cho SW, Kihara S, Funahashi T, Cho YM, Kim SY, Lee HK, Shimomura I, Park KS

Atherosclerosis　Vol. 196　No. 1　p. 398-404　2008/01　Research paper (scientific journal)

Caloric restriction stimulates revascularization in response to ischemia via adiponectin-mediated activation of endothelial nitric-oxide synthase.

Kondo M, Shibata R, Miura R, Shimano M, Kondo K, Li P, Ohashi T, Kihara S, Maeda N, Walsh K, Ouchi N, Murohara T

J Biol Chem.　Vol. 284　No. 3　p. 1718-1724　2008　Research paper (scientific journal)

Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men

Sachiko Tamba, Hitoshi Nishizawa, Tohru Funahashi, Yukiyoshi Okauchi, Tomoko Ogawa, Midori Noguchi, Koichi Fujita, Miwa Ryo, Shinji Kihara, Hiromi Iwahashi, Kazuya Yamagata, Tadashi Nakamura, Iichiro Shimomura, Yuji Matsuzawa

INTERNAL MEDICINE　Vol. 47　No. 13　p. 1175-1180　2008　Research paper (scientific journal)

Nocturnal reduction in circulating adiponectin concentration related to hypoxic stress in severe obstructive sleep apnea hypopnea syndrome.

Nakagawa T, Kishida K, Kihara S, Sonoda M, Hirata A, Yasui A, Nishizawa H, Nakamura T, Yoshida R, Shimomura I, Funahashi T

Am J Physiol Endocrinol Metab　Vol. 294　No. 4　p. E778-E784　2008/01　Research paper (scientific journal)

Clinical Significance of High-Molecular Weight Form of Adiponectin in Male Patients With Coronary Artery Disease.

Komura N, Kihara S, Sonoda M, Kumada M, Fujita K, Hiuge A, Okada T, Nakagawa Y, Tamba S, Kuroda Y, Hayashi N, Sumitsuji S, Kawamoto T, Matsumoto S, Ouchi N, Arita Y, Okamoto Y, Shimomura I, Funahashi T, Matsuzawa Y, for the, Osaka CAD Group

Circ J.　Vol. 72　No. 0　p. 23-28　2008/01　Research paper (scientific journal)

Effect of pravastatin on the development of diabetes and adiponectin production.

Takagi T, Matsuda M, Abe M, Kobayashi H, Fukuhara A, Komuro R, Kihara S, Caslake MJ, McMahon A, Shepherd J, Funahashi T, Shimomura I

Atherosclerosis　Vol. 196　No. 1　p. 114-121　2008/01　Research paper (scientific journal)

Foxol represses expression of musclin, a skeletal muscle-derived secretory factor

Atsutaka Yasui, Hitoshi Nishizawa, Yosuke Okuno, Kentaro Morita, Hironori Kobayashi, Kenichiro Kawai, Morihiro Matsuda, Ken Kishida, Shinji Kihara, Yasutomi Kamei, Yoshihiro Ogawa, Tohru Funahashi, Iichiro Shimomura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 364　No. 2　p. 358-365　2007/12　Research paper (scientific journal)

Erratum (Retracted article): Visfatin: A protein secreted by visceral fat that mimics the effects of insulin (Science))

Atsunori Fukuhara, Morihiro Matsuda, Masako Nishizawa, Katsumori Segawa, Masaki Tanaka, Kae Kishimoto, Yasushi Matsuki, Mirei Murakami, Tomoko Ichisaka, Hiroko Murakami, Eijiro Watanabe, Toshiyuki Takagi, Megumi Akiyoshi, Tsuguteru Ohtsubo, Shinji Kihara, Shizuya Yamashita, Makoto Makishima, Tohru Funahashi, Shinya Yamanaka, Ryuji Hiramatsu, Yuji Matsuzawa, Iichiro Shimomura

Science　Vol. 318　No. 5850　2007/10/26　Research paper (scientific journal)

Adiponectin deficiency suppresses ABCA1 expression and ApoA-I synthesis in the liver.

Oku H, Matsuura F, Koseki M, Sandoval JC, Yuasa-Kawase M, Tsubakio-Yamamoto K, Masuda D, Maeda N, Ohama T, Ishigami M, Nishida M, Hirano K, Kihara S, Hori M, Shimomura I, Yamashita S

FEBS Lett.　Vol. 581　No. 26　p. 5029-5033　2007/10　Research paper (scientific journal)

Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model

Kamada Y, Matsumoto H, Tamura S, Fukushima J, Kiso S, Fukui K, Igura T, Maeda N, Kihara S, Funahashi T, Matsuzawa Y, Shimomura I, Hayashi N

Journal of Hepatology　Vol. 47　No. 4　p. 556-564　2007/10　Research paper (scientific journal)

Reduction of visceral fat is associated with decrease in the number of metabolic risk factors in Japanese men

Yukiyoshi Okauchi, Hitoshi Nishizawa, Tohru Funahashi, Tomoko Ogawa, Midori Noguchi, Miwa Ryo, Shinji Kihara, Hiromi Iwahashi, Kazuya Yamagata, Tadashi Nakamura, Iichiro Shimomura, Yuji Matsuzawa

DIABETES CARE　Vol. 30　No. 9　p. 2392-2394　2007/09　Research paper (scientific journal)

Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice.

Ohashi K, Iwatani H, Kihara S, Nakagawa Y, Komura N, Fujita K, Maeda N, Nishida M, Katsube F, Shimomura I, Ito T, Funahashi T

Arterioscler Thromb Vasc Biol.　Vol. 27　No. 9　p. 1910-1917　2007/09　Research paper (scientific journal)

フィブラートがアディポネクチンに及ぼす影響の分子的解明

日生下 亜紀, 前田 法一, 熊田 全裕, 火伏 俊之, 藤田 幸一, 西澤 均, 木原 進士, 下村 伊一郎, 船橋 徹

日本臨床分子医学会学術総会プログラム・抄録集　Vol. 44回　p. 76-76　2007/07

Adiponectin accelerates reverse cholesterol transport by increasing high density lipoprotein assembly in the liver.

Matsuura F, Oku H, Koseki M, Sandoval JC, Yuasa-Kawase M, Tsubakio-Yamamoto K, Masuda D, Maeda N, Tsujii K, Ishigami M, Nishida M, Hirano K, Kihara S, Hori M, Shimomura I, Yamashita S

Biochem Biophys Res Commun.　Vol. 358　No. 4　p. 1091-1095　2007/07　Research paper (scientific journal)

Adiponectin protects against the development of systolic dysfunction following myocardial infarction.

Shibata R, Izumiya Y, Sato K, Papanicolaou K, Kihara S, Colucci WS, Sam F, Ouchi N, Walsh K

J Mol Cell Cardiol.　Vol. 42　No. 6　p. 1065-1074　2007/06　Research paper (scientific journal)

Adiponectin accumulates in myocardial tissue that has been damaged by ischemia-reperfusion injury via leakage from the vascular compartment.

Shibata R, Sato K, Kumada M, Izumiya Y, Sonoda M, Kihara S, Ouchi N, Walsh K

Cardiovasc Res.　Vol. 74　No. 3　p. 471-479　2007/06　Research paper (scientific journal)

The genes influencing adiponectin levels also influence risk factors for metabolic syndrome and type 2 diabetes

Anthony G. Comuzzie, M. Elizabeth Tejero, Tohru Funahashi, Lisa J. Martin, Ahmed Kissebah, Masahiko Takahashi, Shinji Kihara, Sachiyo Tanaka, David L. Rainwater, Yuji Matsuzawa, Jean W. Maccluer, John Blangero

HUMAN BIOLOGY　Vol. 79　No. 2　p. 191-200　2007/04　Research paper (scientific journal)

Effects of adiponectin on the renal sympathetic nerve activity and blood pressure in rats

Mamoru Tanida, Jiao Shen, Yuko Horii, Morihiro Matsuda, Shinji Kihara, Toru Funahashi, Iichiro Shimomura, Hajime Sawai, Yutaka Fukuda, Yuji Matsuzawa, Katsuya Nagai

EXPERIMENTAL BIOLOGY AND MEDICINE　Vol. 232　No. 3　p. 390-397　2007/03　Research paper (scientific journal)

Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level.

Hiuge A, Tenenbaum A, Maeda N, Benderly M, Kumada M, Fisman EZ, Tanne D, Matas Z, Hibuse T, Fujita K, Nishizawa H, Adler Y, Motro M, Kihara S, Shimomura I, Behar S, Funahashi T

Arterioscler Thromb Vasc Biol.　Vol. 27　No. 3　p. 635-641　2007/03　Research paper (scientific journal)

Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies.

Takemura Y, Ouchi N, Shibata R, Aprahamian T, Kirber MT, Summer RS, Kihara S, Walsh K

J Clin Invest.　Vol. 117　No. 2　p. 375-386　2007/02　Research paper (scientific journal)

Adiponectin and renal function, and risk of cardiovascular disease

Yoshio Iwashima, Takeshi Horio, Yoshihiko Suzuki, Shinji Kihara, Hiromi Rakugi, Yuhei Kawano, Tohru Funahashi, Toshio Ogihara

JOURNAL OF HYPERTENSION　Vol. 24　p. 354-355　2006/12

Adiponectin and renal function, and implication as a risk of cardiovascular disease.

Iwashima Y, Horio T, Kumada M, Suzuki Y, Kihara S, Rakugi H, Kawano Y, Funahashi T, Ogihara T

Am J Cardiol.　Vol. 98　No. 12　p. 1603-8　2006/12　Research paper (scientific journal)

Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation.

Kurata A, Nishizawa H, Kihara S, Maeda N, Sonoda M, Okada T, Ohashi K, Hibuse T, Fujita K, Yasui A, Hiuge A, Kumada M, Kuriyama H, Shimomura I, Funahashi T

Kidney Int.　Vol. 70　No. 10　p. 1717-1724　2006/11　Research paper (scientific journal)

Adiponectin and inflammatory markers in peripheral arterial occlusive disease.

Iwashima Y, Horio T, Suzuki Y, Kihara S, Rakugi H, Kangawa K, Funahashi T, Ogihara T, Kawano Y

Atherosclerosis　Vol. 188　No. 2　p. 384-390　2006/10　Research paper (scientific journal)

Effect of adiponectin on murine colitis induced by dextran sulfate sodium.

Nishihara T, Matsuda M, Araki H, Oshima K, Kihara S, Funahashi T, Shimomura I

Gastroenterology　Vol. 131　No. 3　p. 853-861　2006/09　Research paper (scientific journal)

Adiponectin deficiency exacerbates lipopolysaccharide/D-galactosamine-induced liver injury in mice

Hitoshi Matsumoto, Shinji Tamura, Yoshihiro Kamada, Shinichi Kiso, Juichi Fukushima, Akira Wada, Norikazu Maeda, Shinji Kihara, Tohru Funahashi, Yuji Matsuzawa, Iichiro Shimomura, Norio Hayashi

World Journal of Gastroenterology　Vol. 12　No. 21　p. 3352-3358　2006/06/07　Research paper (scientific journal)

Adiponectin replenishment ameliorates obesity-related hypertension.

Ohashi K, Kihara S, Ouchi N, Kumada M, Fujita K, Hiuge A, Hibuse T, Ryo M, Nishizawa H, Maeda N, Maeda K, Shibata R, Walsh K, Funahashi T, Shimomura I

Hypertension　Vol. 47　No. 6　p. 1108-1116　2006/06　Research paper (scientific journal)

Identification of amino-terminal region of adiponectin as a physiologically functional domain.

Ujiie H, Oritani K, Kato H, Yokota T, Takahashi I, Maeda T, Masaie H, Ichii M, Kamada Y, Tamura S, Kihara S, Funahashi T, Tomiyama Y, Kanakura Y

J Cell Biochem.　Vol. 98　No. 1　p. 194-207　2006/05　Research paper (scientific journal)

アディポネクチンの肝線維化に対する抑制作用

鎌田佳宏, 田村信司, 松本 仁, 佐治雪子, 木曽真一, 福井浩司, 前田法一, 木原進士

2006/04　Research paper (other academic)

Adiponectin and renal function, and implication as a risk of cardiovascular disease.

Iwashima Y, Horio T, Suzuki Y, Kihara S, Rakugi H, Kangawa K, Funahashi T, Ogihara T, Kawano Y

Atherosclerosis　Vol. 188　p. 384-390　2006　Research paper (scientific journal)

Adiponectin inhibits endothelial synthesis of interleukin-8.

Kobashi C, Urakaze M, Kishida M, Kibayashi E, Kobayashi H, Kihara S, Funahashi T, Takata M, Temaru R, Sato A, Yamazaki K, Nakamura N, Kobayashi M

Circ Res.　Vol. 97　No. 12　p. 1245-1252　2005/12　Research paper (scientific journal)

Lack of adiponectin, an adipocytokine, enhanced the progression of non-alcoholic steatohepatitis (NASH).

Yoshihiro Kamada, Shinji Tamura, Hitoshi Matsumoto, Juichi Fukushima, Shinichi Kiso, Koji Fukui, Norikazu Maeda, Hitoshi Nishizawa, Shinji Kihara, Tohru Funahashi, Yuji Matsuzawa, Iichiro Shimomura, Norio Hayashi

2005/11　Research paper (international conference proceedings)

酸化ストレスによるNASHからの発癌に対するアディポネクチンの作用

松本 仁, 田村信司, 鎌田佳宏, 福島寿一, 佐治雪子, 木曽真一, 福井浩司, 前田法一, 木原進士, 篠村恭久, 船橋 徹, 松澤佑次, 下村伊一郎

2005/10　Research paper (other academic)

Adiponectin protects against myocardial ischemia-reperfusion injury through Ampk- and Cox-2-dependent mechanisms

R Shibata, N Ouchi, K Sato, DR Pimentel, K Walsh

CIRCULATION　Vol. 112　No. 17　p. U26-U27　2005/10　Research paper (scientific journal)

アクアポリンアディポースの生体内における機能解析

火伏 俊之, 前田 法一, 船橋 徹, 長澤 安曇, 岸田 堅, 栗山 洋, 中村 正, 木原 進士, 松澤 佑次, 下村 伊一郎

肥満研究　Vol. 11　No. Suppl.　p. 154-154　2005/09

Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase

T Hibuse, N Maeda, T Funahashi, K Yamamoto, A Nagasawa, W Mizunoya, K Kishida, K Inoue, H Kuriyama, T Nakamura, T Fushiki, S Kihara, L Shimomura

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 102　No. 31　p. 10993-10998　2005/08　Research paper (scientific journal)

Pioglitazone improves left ventricular diastolic function in patients with essential hypertension.

Horio T, Suzuki M, Suzuki K, Takamisawa I, Hiuge A, Kamide K, Takiuchi S, Iwashima Y, Kihara S, Funahashi T, Yoshimasa Y, Kawano Y

Am J Hypertens.　Vol. 18　No. 7　p. 949-957　2005/07　Research paper (scientific journal)

Non-alcoholic steatohepatitis (NASH)におけるアディポネクチンの意義について

鎌田佳宏, 田村信司, 松本 仁, 福島寿一, 佐治雪子, 木曽真一, 福井浩司, 前田法一, 木原進士, 宮川潤一郎, 篠村恭久, 船橋 徹, 松澤佑次, 下村伊一郎

2005/06　Research paper (other academic)

アディポネクチンのマクロファージにおけるIL-10・TIMP-1発現増加作用の解明

熊田 全裕, 木原 進士, 大内 乗有, 岡本 芳久, 大橋 浩二, 前田 法一, 前田 和久, 船橋 徹, 下村 伊一郎, 松澤 佑次

日本臨床分子医学会記録　Vol. 41　p. 31-31　2005/05

低アディポネクチン血症と高血圧との関係

大橋 浩二, 木原 進士, 岩嶋 義雄, 船橋 徹, 荻原 俊男, 下村 伊一郎, 松澤 佑次

日本内科学会雑誌　Vol. 94　No. Suppl.　p. 235-235　2005/02

脂肪組織由来血漿蛋白アディポネクチンによる血管障害抑制機序の解明及び血管病の進展抑制に関する研究

木原 進士, 熊田 全裕, 大内 乗有, 岡本 芳久, 流谷 裕幸, 前田 法一, 船橋 徹, 松澤 佑次

代謝異常治療研究基金研究業績集　Vol. 32　p. 41-47　2005/01

Association of hypoadiponectinemia with smoking habit in men.

Iwashima Y, Katsuya T, Ishikawa K, Kida I, Ohishi M, Horio T, Ouchi N, Ohashi K, Kihara S, Funahashi T, Rakugi H, Ogihara T

Hypertension　Vol. 70　No. 0　p. 1094-1100　2005/01　Research paper (scientific journal)

Adiponectin-mediated modulation of hypertrophic signals in the heart

Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K

Nat Med.　Vol. 10　No. 12　p. 1384-1389　2004/12　Research paper (scientific journal)

Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue

Maeda N, Funahashi T, Hibuse T, Nagasawa A, Kishida K, Kuriyama H, Nakamura T, Kihara S, Shimomura I, Matsuzawa Y

Proc Natl Acad Sci U S A　Vol. 101　No. 51　p. 17801-17806　2004/12　Research paper (scientific journal)

Adiponectin as a biomarker of the metabolic syndrome

Miwa Ryo, Tadashi Nakamura, Shinji Kihara, Masahiro Kumada, Satomi Shibazaki, Mihoko Takahashi, Masaki Nagai, Yuji Matsuzawa, Tohru Funahashi

Circulation Journal　Vol. 68　No. 11　p. 975-981　2004/11　Research paper (scientific journal)

アディポネクチンの血管新生作用に及ぼすメカニズム

熊田 全裕, 大内 乗有, 木原 進士, 小林 英毅, Walsh Kenneth, 下村 伊一郎, 船橋 徹

肥満研究　Vol. 10　No. Suppl.　p. 196-196　2004/09

アディポネクチン多量体の血管内皮細胞に対する抗アポトーシス作用

熊田 全裕, 小林 英毅, 木原 進士, 大内 乗有, Walsh Kenneth, 下村 伊一郎, 船橋 徹

肥満研究　Vol. 10　No. Suppl.　p. 197-197　2004/09

アディポネクチンのマクロファージにおけるIL-10・TIMP-1発現増加作用の解明

熊田 全裕, 木原 進士, 大内 乗有, 岡本 芳久, 大橋 浩二, 前田 法一, 前田 和久, 船橋 徹, 下村 伊一郎, 松澤 佑次

日本臨床分子医学会学術総会プログラム・抄録集　Vol. 41回　p. 39-39　2004/07

アディポネクチンのマクロファージにおける抗炎症機序

熊田 全裕, 木原 進士, 大内 乗有, 大橋 浩二, 前田 法一, 流谷 裕幸, 火伏 俊之, 前田 和久, 船橋 徹, 松澤 佑次

日本動脈硬化学会総会プログラム・抄録集　Vol. 36回　p. 221-221　2004/07

Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling.

Shibata R, Ouchi N, Kihara S, Sato K, Funahashi T, Walsh K

J Biol Chem.　Vol. 279　No. 27　p. 28670-28674　2004/06　Research paper (scientific journal)

Hypoadiponectinemia is an independent risk factor for hypertension

Iwashima Y, Katsuya T, Ishikawa K, Ouchi N, Ohishi M, Sugimoto K, Fu Y, Motone M, Yamamoto K, Matsuo A, Ohashi K, Kihara S, Funahashi T, Rakugi H, Matsuzawa Y, Ogihara T

Hypertension　Vol. 43　No. 6　p. 1318-1323　2004/06　Research paper (scientific journal)

Adiponectin as a potential key player in metabolic syndrome: Insights into atherosclerosis, diabetes and cancer

Tohru Funahashi, Yuji Matsuzawa, Shinji Kihara

International Congress Series　Vol. 1262　No. C　p. 368-371　2004/05/01　Research paper (scientific journal)

メタボリックシンドロームを伴うアディポネクチン遺伝子変異の解析

火伏 俊之, 大橋 浩二, 熊田 全裕, 前田 法一, 流谷 裕幸, 近藤 秀彦, 長澤 安曇, 小林 英毅, 西澤 均, 岸田 堅, 前田 和久, 下村 伊一郎, 木原 進士, 船橋 徹, 松澤 佑次

日本内分泌学会雑誌　Vol. 80　No. 1　p. 115-115　2004/04

Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin.

Kobayashi H, Ouchi N, Kihara S, Walsh K, Kumada M, Abe Y, Funahashi T, Matsuzawa Y

Circ Res.　Vol. 94　No. 4　p. E27-E31　2004/03　Research paper (scientific journal)

Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis.

Brakenhielm E, Veitonmaki N, Cao R, Kihara S, Matsuzawa Y, Zhivotovsky B, Funahashi T, Cao Y

Proc Natl Acad Sci U S A.　Vol. 101　No. 8　p. 2476-2481　2004/02　Research paper (scientific journal)

脂肪組織由来血漿蛋白アディポネクチンによる血管障害抑制機序の解明及び血管病の進展抑制に関する研究

木原 進士, 大内 乗有, 有田 幸生, 岡本 芳久, 流谷 裕幸, 前田 法一, 船橋 徹, 松澤 佑次

代謝異常治療研究基金研究業績集　Vol. 31　p. 31-38　2004/01

Effect of Moderate Alcohol Consumption on Adiponectin, Tumor Necrosis Factor-α, and Insulin Sensitivity

Aafje Sierksma, Hamina Patel, Noriyuki Ouchi, Shinji Kihara, Tohru Funahashi, Robert J. Heine, Diederick E. Grobbee, Cornelis Kluft, Henk F.J. Hendriks

Diabetes Care　Vol. 27　No. 1　p. 184-189　2004/01　Research paper (scientific journal)

Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells

N Ouchi, H Kobayashi, S Kihara, M Kumada, K Sato, T Inoue, T Funahashi, K Walsh

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 279　No. 2　p. 1304-1309　2004/01　Research paper (scientific journal)

Obesity, adiponectin and vascular inflammatory disease

Noriyuki Ouchi, Shinji Kihara, Tohru Funahashi, Yuji Matsuzawa, Kenneth Walsh

Current Opinion in Lipidology　Vol. 14　No. 6　p. 561-566　2003/12

Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin

Kamada Y, Tamura S, Kiso S, Matsumoto H, Saji Y, Yoshida Y, Fukui K, Maeda N, Nishizawa H, Nagaretani H, Okamoto Y, Kihara S, Miyagawa J, Shinomura Y, Funahashi T, Matsuzawa Y

Gastroenterology　Vol. 125　No. 6　p. 1796-1807　2003/12　Research paper (scientific journal)

Adiponectin, an adipocytokine, attenuates carbon-tetrachloride induced liver fibrosis in mice.

Yoshihiro Kamada, Shinji Tamura, Shinichi Kiso, Hitoshi Matsumoto, Yukiko Saji, Yuichi Yoshida, Koji Fukui, Norikazu Maeda, Hitoshi Nishizawa, Hiroyuki Nagaretani, Yoshihisa Okamoto, Shinji Kihara, Jun-ichiro Miyagawa, Tohru Funahashi, Yasuhisa Shinomura, Yuji Matsuzawa

2003/11　Research paper (international conference proceedings)

Divergent effects of soy protein diet on the expression of adipocytokines.

Nagasawa A, Fukui K, Kojima M, Kishida K, Maeda N, Nagaretani H, Hibuse T, Nishizawa H, Kihara S, Waki M, Takamatsu K, Funahashi T, Matsuzawa Y

Biochem Biophys Res Commun.　Vol. 311　No. 4　p. 909-914　2003/11　Research paper (scientific journal)

Association of serum adiponectin levels with breast cancer risk.

Miyoshi Y, Funahashi T, Kihara S, Taguchi T, Tamaki Y, Matsuzawa Y, Noguchi S

Clin Cancer Res.　Vol. 9　No. 15　p. 5699-5704　2003/11　Research paper (scientific journal)

脂肪蓄積に関わる遺伝子解析の新展開 メタボリックシンドロームを伴うアディポネクチン遺伝子変異の分子解析

火伏 俊之, 岸田 堅, 流谷 裕幸, 近藤 秀彦, 小林 英毅, 前田 法一, 長澤 安曇, 大橋 浩二, 熊田 全裕, 西澤 均, 前田 和久, 下村 伊一郎, 木原 進士, 船橋 徹, 松澤 佑次

肥満研究　Vol. 9　No. Suppl.　p. 82-82　2003/10

肝臓におけるアディポネクチンの作用について

鎌田佳宏, 田村信司, 松本 仁, 佐治雪子, 木曽真一, 吉田雄一, 福井浩司, 前田法一, 木原進士, 宮川潤一郎, 船橋 徹, 篠村恭久, 松澤佑次

2003/10　Research paper (other academic)

Association of hypoadiponectinemia with impaired vasoreactivity.

Ouchi N, Ohishi M, Kihara S, Funahashi T, Nakamura T, Nagaretani H, Kumada M, Ohashi K, Okamoto Y, Nishizawa H, Kishida K, Maeda N, Nagasawa A, Kobayashi H, Hiraoka H, Komai N, Kaibe M, Rakugi H, Ogihara T, Matsuzawa Y

Hypertension　Vol. 42　No. 3　p. 231-234　2003/09　Research paper (scientific journal)

Measurement of fasting serum apoB-48 levels in normolipidemic and hyperlipidemic subjects by ELISA.

Sakai N, Uchida Y, Ohashi K, Hibuse T, Saika Y, Tomari Y, Kihara S, Hiraoka H, Nakamura T, Ito S, Yamashita S, Matsuzawa Y

J Lipid Res.　Vol. 44　No. 6　p. 1256-1262　2003/06　Research paper (scientific journal)

The variation of plasma concentrations of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction.

Kojima S, Funahashi T, Sakamoto T, Miyamoto S, Soejima H, Hokamaki J, Kajiwara I, Sugiyama S, Yoshimura M, Fujimoto K, Miyao Y, Suefuji H, Kitagawa A, Ouchi N, Kihara S, Matsuzawa Y, Ogawa H

Heart　Vol. 89　No. 6　p. 667-668　2003/06　Research paper (scientific journal)

Disturbed secretion of mutant adiponectin associated with the metabolic syndrome.

Kishida K, Nagaretani H, Kondo H, Kobayashi H, Tanaka S, Maeda N, Nagasawa A, Hibuse T, Ohashi K, Kumada M, Nishizawa H, Okamoto Y, Ouchi N, Maeda K, Kihara S, Funahashi T, Matsuzawa Y

Biochem Biophys Res Commun.　Vol. 306　No. 1　p. 286-292　2003/06　Research paper (scientific journal)

Adiponectin is markedly increased in patients with nephrotic syndrome and is related to metabolic risk factors.

Zoccali C, Mallamaci F, Panuccio V, Tripepi G, Cutrupi S, Parlongo S, Catalano F, Tanaka S, Ouchi N, Kihara S, Funahashi T, Matsuzawa Y

Kidney Int Suppl.　Vol. 63　p. S98-S102　2003/05　Research paper (scientific journal)

Novel LPL mutation (L303F) found in a patient associated with coronary artery disease and severe systemic atherosclerosis.

Saika Y, Sakai N, Takahashi M, Maruyama T, Kihara S, Ouchi N, Ishigami M, Hiraoka H, Nakamura T, Yamashita S, Matsuzawa Y

Eur J Clin Invest.　Vol. 33　No. 3　p. 216-222　2003/03　Research paper (scientific journal)

Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue

N Ouchi, S Kihara, T Funahashi, T Nakamura, M Nishida, M Kumada, Y Okamoto, K Ohashi, H Nagaretani, K Kishida, H Nishizawa, N Maeda, H Kobayashi, H Hiraoka, Y Matsuzawa

CIRCULATION　Vol. 107　No. 5　p. 671-674　2003/02　Research paper (scientific journal)

Importance of adipocytokines in obesity-related diseases

Yuji Matsuzawa, Iichiro Shimomura, Shinji Kihara, Tohru Funahashi

Hormone Research　Vol. 60　No. 3　p. 56-59　2003　Research paper (international conference proceedings)

Association of hypoadiponectinemia with coronary artery disease in men

M Kumada, S Kihara, S Sumitsuji, T Kawamoto, S Matsumoto, N Ouchi, Y Arita, Y Okamoto, Shimomura, I, H Hiraoka, T Nakamura, T Funahashi, Y Matsuzawa

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY　Vol. 23　No. 1　p. 85-89　2003/01　Research paper (scientific journal)

Adiponectin, an adipocyte-derived hormone, suppressed the proliferation, migration, and expression of genes involved in the hepatic fibrosis of hepatic stellate cells.

Yoshihiro Kamada, Shinji Tamura, Shinichi Kiso, Yuichi Yoshida, Koji Fukui, Norikazu Maeda, Hitoshi Nshizawa, Hiroyuki Nagaretani, yoshihisa Okamoto, Shinji Kihara, Tohru Funahashi, Yuji Matauzawa

2002/11　Research paper (international conference proceedings)

Effects of soy protein diet on the expression of adipose genes and plasma adiponectin.

Nagasawa A, Fukui K, Funahashi T, Maeda N, Shimomura I, Kihara S, Waki M, Takamatsu K, Matsuzawa Y

Horm Metab Res.　Vol. 34　No. 11-12　p. 635-639　2002/11　Research paper (scientific journal)

Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice.

Okamoto Y, Kihara S, Ouchi N, Nishida M, Arita Y, Kumada M, Ohashi K, Sakai N, Shimomura I, Kobayashi H, Terasaka N, Inaba T, Funahashi T, Matsuzawa Y

Circulation　Vol. 106　No. 22　p. 2767-2770　2002/11　Research paper (scientific journal)

Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9

H Kuriyama, Shimomura, I, K Kishida, H Kondo, N Furuyama, H Nishizawa, N Maeda, M Matsuda, H Nagaretani, S Kihara, T Nakamura, Y Tochino, T Funahashi, Y Matsuzawa

DIABETES　Vol. 51　No. 10　p. 2915-2921　2002/10　Research paper (scientific journal)

Role of adiponectin in preventing vascular stenosis - The missing link of adipo-vascular axis

M Matsuda, Shimomura, I, M Sata, Y Arita, M Nishida, N Maeda, M Kumada, Y Okamoto, H Nagaretani, H Nishizawa, K Kishida, R Komuro, N Ouchi, S Kihara, R Nagai, T Funahashi, Y Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 277　No. 40　p. 37487-37491　2002/10　Research paper (scientific journal)

Adiponectin in essential hypertension

F Mallamaci, C Zoccali, F Cuzzola, G Tripepi, S Cutrupi, S Parlongo, S Tanaka, N Ouchi, S Kihara, T Funahashi, Y Matsuzawa

JOURNAL OF NEPHROLOGY　Vol. 15　No. 5　p. 507-511　2002/09　Research paper (scientific journal)

Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein

H Nishizawa, H Shimomura, K Kishida, N Maeda, H Kuriyama, H Nagaretani, M Matsuda, H Kondo, N Furuyama, S Kihara, T Nakamura, Y Tochino, T Funahashi, Y Matsuzawa

DIABETES　Vol. 51　No. 9　p. 2734-2741　2002/09　Research paper (scientific journal)

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

N Maeda, Shimomura, I, K Kishida, H Nishizawa, M Matsuda, H Nagaretani, N Furuyama, H Kondo, M Takahashi, Y Arita, R Komuro, N Ouchi, S Kihara, Y Tochino, K Okutomi, M Horie, S Takeda, T Aoyama, T Funahashi, Y Matsuzawa

NATURE MEDICINE　Vol. 8　No. 7　p. 731-737　2002/07　Research paper (scientific journal)

Association of adiponectin mutation with type 2 diabetes - A candidate gene for the insulin resistance syndrome

H Kondo, Shimomura, I, Y Matsukawa, M Kumada, M Takahashi, M Matsuda, N Ouchi, S Kihara, T Kawamoto, S Sumitsuji, T Funahashi, Y Matsuzawa

DIABETES　Vol. 51　No. 7　p. 2325-2328　2002/07　Research paper (scientific journal)

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell

Y Arita, S Kihara, N Ouchi, K Maeda, H Kuriyama, Y Okamoto, M Kumada, K Hotta, M Nishida, M Takahashi, T Nakamura, Shimomura, I, M Muraguchi, Y Ohmoto, T Funahashi, Y Matsuzawa

CIRCULATION　Vol. 105　No. 24　p. 2893-2898　2002/06　Research paper (scientific journal)

Human aquaporin adipose (AQPap) gene - Genomic structure, promoter analysis and functional mutation

H Kondo, Shimomura, I, K Kishida, H Kuriyama, Y Makino, H Nishizawa, M Matsuda, N Maeda, H Nagaretani, S Kihara, Y Kurachi, T Nakamura, T Funahashi, Y Matsuzawa

EUROPEAN JOURNAL OF BIOCHEMISTRY　Vol. 269　No. 7　p. 1814-1826　2002/04　Research paper (scientific journal)

Increased plasma HB-EGF associated with obesity and coronary artery disease

S Matsumoto, K Kishida, Shimomura, I, N Maeda, H Nagaretani, M Matsuda, H Nishizawa, S Kihara, T Funahashi, Y Matsuzawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 292　No. 3　p. 781-786　2002/04　Research paper (scientific journal)

Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease

C Zoccali, F Mallamaci, G Tripepi, FA Benedetto, S Cutrupi, S Parlongo, LS Malatino, G Bonanno, G Seminara, F Rapisarda, P Fatuzzo, M Buemi, G Nicocia, S Tanaka, N Ouchi, S Kihara, T Funahashi, Y Matsuzawa

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY　Vol. 13　No. 1　p. 134-141　2002/01　Research paper (scientific journal)

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

H Nishizawa, K Yamagata, L Shimomura, M Takahashi, H Kuriyama, K Kishida, K Hotta, H Nagaretani, N Maeda, M Matsuda, S Kihara, T Nakamura, H Nishigori, H Tomura, DD Moore, J Takeda, T Funahashi, Y Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 277　No. 2　p. 1586-1592　2002/01　Research paper (scientific journal)

Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation - double-blind placebo-controlled trial

T Nakamura, T Funahashi, S Yamashita, M Nishida, Y Nishida, M Takahashi, K Hotta, H Kuriyama, S Kihara, N Ohuchi, T Nishimura, B Kishino, K Ishikawa, T Kawamoto, K Tokunaga, C Nakagawa, Mineo, I, F Watanabe, S Tarui, Y Matsuzawa

DIABETES RESEARCH AND CLINICAL PRACTICE　Vol. 54　No. 3　p. 181-190　2001/12　Research paper (scientific journal)

Enhancement of the aquaporin adipose gene expression by a peroxisome proliferator-activated receptor g

Kishida K, Shimomura I, Nishizawa H, Maeda N, Kuriyama H, Kondo H, Matsuda M, Nagaretani H, Ouchi N, Hotta K, Kihara S, Kadowaki T, Funahashi T, Matsuzawa Y

Journal of Biological Chemistry　Vol. 276　p. 48572-48579　2001/10　Research paper (scientific journal)

The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome

AG Comuzzie, T Funahashi, G Sonnenberg, LJ Martin, HJ Jacob, AEK Black, D Maas, M Takahashi, S Kihara, S Tanaka, Y Matsuzawa, J Blangero, D Cohen, A Kissebah

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM　Vol. 86　No. 9　p. 4321-4325　2001/09　Research paper (scientific journal)

Galectin-12, an adipose-expressed galectin-like molecule possessing apoptosis-inducing activity

K Hotta, T Funahashi, Y Matsukawa, M Takahashi, H Nishizawa, K Kishida, M Matsuda, H Kuriyama, S Kihara, T Nakamura, Y Tochino, NL Bodkin, BC Hansen, Y Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 276　No. 36　p. 34089-34097　2001/09　Research paper (scientific journal)

PPAR gamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

N Maeda, M Takahashi, T Funahashi, S Kihara, H Nishizawa, K Kishida, H Nagaretani, M Matsuda, R Komuro, N Ouchi, H Kuriyama, K Hotta, T Nakamura, Shimomura, I, Y Matsuzawa

DIABETES　Vol. 50　No. 9　p. 2094-2099　2001/09　Research paper (scientific journal)

Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel

K Kishida, Shimomura, I, H Kondo, H Kuriyama, Y Makino, H Nishizawa, N Maeda, M Matsuda, N Ouchi, S Kihara, Y Kurachi, T Funahashi, Y Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 276　No. 39　p. 36251-36260　2001/09　Research paper (scientific journal)

The expression of SPARC in adipose tissue and its increased plasma concentration in patients with coronary artery disease

M Takahashi, H Nagaretani, T Funahashi, H Nishizawa, N Maeda, K Kishida, H Kuriyama, Shimomura, I, K Maeda, K Hotta, N Ouchi, S Kihara, T Nakamura, S Yamashita, Y Matsuzawa

OBESITY RESEARCH　Vol. 9　No. 7　p. 388-393　2001/07　Research paper (scientific journal)

Immunohistochemical localization of Betacellulin, a member of epidermal growth factor family, in atherosclerotic plaques of human aorta

R Tamura, J Miyagawa, M Nishida, S Kihara, R Sasada, K Igarashi, A Nakata, K Yamamori, K Kameda-Takemura, S Yamashita, Y Matsuzawa

ATHEROSCLEROSIS　Vol. 155　No. 2　p. 413-423　2001/04　Research paper (scientific journal)

Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages

N Ouchi, S Kihara, Y Arita, M Nishida, A Matsuyama, Y Okamoto, M Ishigami, H Kuriyama, K Kishida, H Nishizawa, K Hotta, M Muraguchi, Y Ohmoto, S Yamashita, T Funahashi, Y Matsuzawa

CIRCULATION　Vol. 103　No. 8　p. 1057-1063　2001/02　Research paper (scientific journal)

Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappa B signaling through a cAMP-dependent pathway

N Ouchi, S Kihara, Y Arita, Y Okamoto, K Maeda, H Kuriyama, K Hotta, M Nishida, M Takahashi, M Muraguchi, Y Ohmoto, T Nakamura, S Yamashita, T Funahashi, Y Matsuzawa

CIRCULATION　Vol. 102　No. 11　p. 1296-1301　2000/09　Research paper (scientific journal)

Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

T Yokota, K Oritani, Takahashi, I, J Ishikawa, A Matsuyama, N Ouchi, S Kihara, T Funahashi, AJ Tenner, Y Tomiyama, Y Matsuzawa

BLOOD　Vol. 96　No. 5　p. 1723-1732　2000/09　Research paper (scientific journal)

Aquaporin adipose, a putative glycerol channel in adipocytes

K Kishida, H Kuriyama, T Funahashi, Shimomura, I, S Kihara, N Ouchi, M Nishida, H Nishizawa, M Matsuda, M Takahashi, K Hotta, T Nakamura, S Yamashita, Y Tochino, Y Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 275　No. 27　p. 20896-20902　2000/07　Research paper (scientific journal)

Genomic structure and mutations in adipose-specific gene, adiponectin

M Takahashi, Y Arita, K Yamagata, Y Matsukawa, K Okutomi, M Horie, Shimomura, I, K Hotta, H Kuriyama, S Kihara, T Nakamura, S Yamashita, T Funahashi, Y Matsuzawa

INTERNATIONAL JOURNAL OF OBESITY　Vol. 24　No. 7　p. 861-868　2000/07　Research paper (scientific journal)

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients

K Hotta, T Funahashi, Y Arita, M Takahashi, M Matsuda, Y Okamoto, H Iwahashi, H Kuriyama, N Ouchi, K Maeda, M Nishida, S Kihara, N Sakai, T Nakajima, K Hasegawa, M Muraguchi, Y Ohmoto, T Nakamura, S Yamashita, T Hanafusa, Y Matsuzawa

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY　Vol. 20　No. 6　p. 1595-1599　2000/06　Research paper (scientific journal)

Identification of a GPI-anchored type HDL-binding protein on human macrophages

A Matsuyama, S Yamashita, N Sakai, T Maruyama, E Okuda, K Hirano, S Kihara, H Hiraoka, Y Matsuzawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 272　No. 3　p. 864-871　2000/06　Research paper (scientific journal)

Localization of CD9, an enhancer protein for proheparin-binding epidermal growth factor-like growth factor, in human atherosclerotic plaques - Possible involvement of juxtacrine growth mechanism on smooth muscle cell proliferation

M Nishida, J Miyagawa, S Yamashita, S Higashiyama, A Nakata, N Ouchi, R Tamura, K Yamamori, S Kihara, N Taniguchi, Y Matsuzawa

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY　Vol. 20　No. 5　p. 1236-1243　2000/05　Research paper (scientific journal)

An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls

Y Okamoto, Y Arita, M Nishida, M Muraguchi, N Ouchi, M Takahashi, T Igura, Y Inui, S Kihara, T Nakamura, S Yamashita, J Miyagawa, T Funahashi, Y Matsuzawa

HORMONE AND METABOLIC RESEARCH　Vol. 32　No. 2　p. 47-50　2000/02　Research paper (scientific journal)

Novel modulator for endothelial adhesion molecules - Adipocyte-derived plasma protein adiponectin

N Ouchi, S Kihara, Y Arita, K Maeda, H Kuriyama, Y Okamoto, K Hotta, M Nishida, M Takahashi, T Nakamura, S Yamashita, T Funahashi, Y Matsuzawa

CIRCULATION　Vol. 100　No. 25　p. 2473-2476　1999/12　Research paper (scientific journal)

脂肪細胞由来血漿蛋白アディポネクチンの抗動脈硬化作用

大内 乗有, 松山 晃文, 有田 幸生, 岡本 芳久, 高橋 雅彦, 木原 進士, 船橋 徹, 山下 静也, 松澤 佑次

動脈硬化　Vol. 27　No. Suppl.1　p. 106-106　1999/11

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

Y Arita, S Kihara, N Ouchi, M Takahashi, K Maeda, J Miyagawa, K Hotta, Shimomura, I, T Nakamura, K Miyaoka, H Kuriyama, M Nishida, S Yamashita, K Okubo, K Matsubara, M Muraguchi, Y Ohmoto, T Funahashi, Y Matsuzawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 257　No. 1　p. 79-83　1999/04　Research paper (scientific journal)

High concentration of glucose induces the expression of intercellular adhesion molecule-1 in human umbilical vein endothelial cells

S Takami, S Yamashita, S Kihara, K Kameda-Takemura, Y Matsuzawa

ATHEROSCLEROSIS　Vol. 138　No. 1　p. 35-41　1998/05　Research paper (scientific journal)

Lipoprotein(a) enhances the expression of intercellular adhesion molecule-1 in cultured human umbilical vein endothelial cells

S Takami, S Yamashita, S Kihara, M Ishigami, K Takemura, N Kume, T Kita, Y Matsuzawa

CIRCULATION　Vol. 97　No. 8　p. 721-728　1998/03　Research paper (scientific journal)

Troglitazone suppresses intimal formation following balloon injury in insulin-resistant Zucker fatty rats

E Shinohara, S Kihara, N Ouchi, T Funahashi, T Nakamura, S Yamashita, K Kameda-Takemura, Y Matsuzawa

ATHEROSCLEROSIS　Vol. 136　No. 2　p. 275-279　1998/02　Research paper (scientific journal)

Troglitazone enhances glucose uptake and inhibits mitogen-activated protein kinase in human aortic smooth muscle cells

S Kihara, N Ouchi, T Funahashi, E Shinohara, R Tamura, S Yamashita, Y Matsuzawa

ATHEROSCLEROSIS　Vol. 136　No. 1　p. 163-168　1998/01　Research paper (scientific journal)

Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophages

N Ouchi, SJ Kihara, S Yamashita, S Higashiyama, T Nakagawa, Shimomura, I, T Funahashi, K Kameda-Takemura, S Kawata, N Taniguchi, Y Matsuzawa

BIOCHEMICAL JOURNAL　Vol. 328　p. 923-928　1997/12　Research paper (scientific journal)

Importance of intra-abdominal visceral fat accumulation to coronary atherosclerosis in heterozygous familial hypercholesterolaemia

T Nakamura, H Kobayashi, K Yanagi, T Nakagawa, M Nishida, S Kihara, H Hiraoka, S Nozaki, T Funahashi, S Yamashita, K KamedaTakemura, Y Matsuzawa

INTERNATIONAL JOURNAL OF OBESITY　Vol. 21　No. 7　p. 580-586　1997/07　Research paper (scientific journal)

Characteristics of coronary artery disease and lipoprotein abnormalities in patients with heterozygous familial hypercholesterolemia associated with diabetes mellitus or impaired glucose tolerance

K Yanagi, S Yamashita, S Kihara, T Nakamura, S Nozaki, Y Nagai, T Funahashi, K KamedaTakemura, Y Ueyama, S Jiao, M Kubo, K Tokunaga, Y Matsuzawa

ATHEROSCLEROSIS　Vol. 132　No. 1　p. 43-51　1997/07　Research paper (scientific journal)

Interferon alpha induces disorder of lipid metabolism by lowering postheparin lipases and cholesteryl ester transfer protein activities in patients with chronic hepatitis C

E Shinohara, S Yamashita, S Kihara, K Hirano, M Ishigami, T Arai, S Nozaki, K KamedaTakemura, S Kawata, Y Matsuzawa

HEPATOLOGY　Vol. 25　No. 6　p. 1502-1506　1997/06　Research paper (scientific journal)

Increased serum remnant lipoproteins in patients with apolipoprotein E7 (apo E-Suita)

K Yanagi, S Yamashita, H Hiraoka, M Ishigami, S Kihara, K Hirano, N Sakai, S Nozaki, T Funahashi, K KamedaTakemura, M Kubo, K Tokunaga, Y Matsuzawa

ATHEROSCLEROSIS　Vol. 131　No. 1　p. 49-58　1997/05　Research paper (scientific journal)

Visceral fat accumulation as an important risk factor for obstructive sleep apnoea syndrome in obese subjects

E Shinohara, S Kihara, S Yamashita, M Yamane, M Nishida, T Arai, K Kotani, T Nakamura, K Takemura, Y Matsuzawa

JOURNAL OF INTERNAL MEDICINE　Vol. 241　No. 1　p. 11-18　1997/01　Research paper (scientific journal)

INCREASED PROPORTION OF PLASMA APO-B-48 TO APO-B-100 IN NON-INSULIN-DEPENDENT DIABETIC RATS - CONTRIBUTION OF ENHANCED APO-B MESSENGER-RNA EDITING IN THE LIVER

M YAMANE, S JIAO, S KIHARA, SHIMOMURA, I, K YANAGI, K TOKUNAGA, S KAWATA, H ODAKA, H IKEDA, S YAMASHITA, K KAMEDATAKEMURA, Y MATSUZAWA

JOURNAL OF LIPID RESEARCH　Vol. 36　No. 8　p. 1676-1685　1995/08　Research paper (scientific journal)

REGULATION OF HEPATIC TRIGLYCERIDE LIPASE BY THYROID-HORMONE IN HEPG2 CELLS

S KIHARA, J WOLLE, C EHNHOLM, L CHAN, K OKA

JOURNAL OF LIPID RESEARCH　Vol. 34　No. 6　p. 961-970　1993/06　Research paper (scientific journal)

A MISSENSE MUTATION (TRP86-]ARG) IN EXON-3 OF THE LIPOPROTEIN-LIPASE GENE - A CAUSE OF FAMILIAL CHYLOMICRONEMIA

K ISHIMURAOKA, F FAUSTINELLA, S KIHARA, LC SMITH, K OKA, L CHAN

AMERICAN JOURNAL OF HUMAN GENETICS　Vol. 50　No. 6　p. 1275-1280　1992/06　Research paper (scientific journal)

AUTOIMMUNE HYPERCHYLOMICRONEMIA

S KIHARA, Y MATSUZAWA, M KUBO, S NOZAKI, T FUNAHASHI, S YAMASHITA, N SHO, S TARUI

NEW ENGLAND JOURNAL OF MEDICINE　Vol. 320　No. 19　p. 1255-1259　1989/05　Research paper (scientific journal)

INHIBITION OF PURIFIED HUMAN POSTHEPARIN LIPOPROTEIN-LIPASE BY BETA-ADRENERGIC BLOCKERS INVITRO

S KIHARA, M KUBO, N IKEDA, S YOKOYAMA, Y MATSUZAWA, S TARUI, A YAMAMOTO, KY HOSTETLER

BIOCHEMICAL PHARMACOLOGY　Vol. 38　No. 3　p. 407-411　1989/02　Research paper (scientific journal)

Studies on the two families of hyperalphalipoproteinemia caused by complete deficiency of cholesteryl ester transfer activity - Existence of small polydisperse LDL and markedly large HDL

S. Yamashita, Y. Ueyama, S. Kihara, T. Kawamoto, T. Nakamura, M. Kubo, Y. Matsuzawa, S. Tarui, H. Kako, G. Mizuno, T. Yasugi, H. Akioka, K. Hirano, M. Okazaki

Journal of Japan Atherosclerosis Society　Vol. 17　No. 2　p. 371-379　1989　Research paper (scientific journal)

The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.

Hibuse T, Maeda N, Nakatsuji H, Tochino Y, Fujita K, Kihara S, Funahashi T, Shimomura I

Cardiovasc Res.　Vol. 83　p. 34-41　Research paper (scientific journal)