JA

Profile

Research

Social

Other

Nakagami Hironori

中神 啓徳

Graduate School of Medicine, Endowed Chair Professor

Research Areas

  • Life sciences, Internal medicine - General

Papers

  • Development of anti-thrombotic vaccine against human S100A9 in rhesus monkey., Munehisa Shimamura,Koichi Kaikita,Hironori Nakagami,Tomohiro Kawano,Nan Ju,Hiroki Hayashi,Ryo Nakamaru,Shota Yoshida,Tsutomu Sasaki,Hideki Mochizuki,Kenichi Tsujita,Ryuichi Morishita, Scientific reports, Vol. 11, No. 1, p. 11472-11472, 2021/06/01
  • SARS-CoV-2-induced humoral immunity through B cell epitope analysis in COVID-19 infected individuals., Shota Yoshida,Chikako Ono,Hiroki Hayashi,Shinya Fukumoto,Satoshi Shiraishi,Kazunori Tomono,Hisashi Arase,Yoshiharu Matsuura,Hironori Nakagami, Scientific reports, NATURE RESEARCH, Vol. 11, No. 1, p. 5934-5934, 2021/03/15
  • Performance Index for Types of Clinical Research Support Service Providers for Academic Research Organizations in Japan: A Cross-Sectional Survey., Keiko Ueda,Naoto Uemura,Kotone Matsuyama,Yuji Nishizaki,Nanae Tanemura,Kento Asano,Yuki Otsuka,Naotake Yanagisawa,Toshiaki Otsuka,Shinji Yasuno,Rieko Ueda,Yumiko Seo,Hironori Nakagami,Shoji Sanada, Clinical and translational science, Vol. 14, No. 2, p. 745-755, 2021/03
  • Management guideline for Werner syndrome 2020. 5. Infection associated with Werner syndrome., Toshibumi Taniguchi,Minoru Takemoto,Yoshitaka Kubota,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 150-152, 2021/02
  • Management guideline for Werner syndrome 2020. 7. Skin ulcer associated with Werner syndrome: Dermatological treatment., Sei-Ichiro Motegi,Minoru Takemoto,Toshibumi Taniguchi,Yoshitaka Kubota,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 160-162, 2021/02
  • Management guideline for Werner syndrome 2020. 4. Osteoporosis associated with Werner syndrome., Seijiro Mori,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 146-149, 2021/02
  • Management guideline for Werner syndrome 2020. 2. Sarcopenia associated with Werner syndrome., Masafumi Kuzuya,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 139-141, 2021/02
  • Management guideline for Werner syndrome 2020. 3. Diabetes associated with Werner syndrome., Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Kazuhisa Tsukamoto,Seijiro Mori,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 142-145, 2021/02
  • Management guideline for Werner syndrome 2020. 6. Skin ulcers associated with Werner syndrome: Prevention and non-surgical and surgical treatment., Yoshitaka Kubota,Minoru Takemoto,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 153-159, 2021/02
  • Management guideline for Werner syndrome 2020 1. Dyslipidemia and fatty liver associated with Werner syndrome., Kazuhisa Tsukamoto,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 133-138, 2021/02
  • Management guideline for Werner syndrome 2020 8. Calcification in tendons associated with Werner syndrome., Akira Taniguchi,Yasuhito Tanaka,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Kazuhisa Tsukamoto,Seijiro Mori,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 163-165, 2021/02
  • A novel angiotensin II peptide vaccine without an adjuvant in mice., Ryo Nakamaru,Hironori Nakagami,Hiroki Hayashi,Jiao Sun,Akiko Tenma,Koichi Yamamoto,Munehisa Shimamura,Ryuichi Morishita,Hiromi Rakugi, Journal of hypertension, Vol. 39, No. 1, p. 181-189, 2021/01
  • Time gap between the onset and diagnosis in Werner syndrome: a nationwide survey and the 2020 registry in Japan., Masaya Koshizaka,Yoshiro Maezawa,Yukari Maeda,Mayumi Shoji,Hisaya Kato,Hiyori Kaneko,Takahiro Ishikawa,Daisuke Kinoshita,Kazuki Kobayashi,Junji Kawashima,Akiko Sekiguchi,Sei-Ichiro Motegi,Hironori Nakagami,Yoshihiko Yamada,Shinji Tsukamoto,Akira Taniguchi,Ken Sugimoto,Yukiko Shoda,Kunihiko Hashimoto,Toru Yoshimura,Daisuke Suzuki,Masafumi Kuzuya,Minoru Takemoto,Koutaro Yokote, Aging, Vol. 12, No. 24, p. 24940-24956, 2020/12/29
  • Prevention of Progression of Aortic Aneurysm by Peptide Vaccine Against Ang II (Angiotensin II) in a Rat Model., Tomohiro Kurashiki,Takashi Miyake,Hironori Nakagami,Motonobu Nishimura,Ryuichi Morishita, Hypertension (Dallas, Tex. : 1979), Vol. 76, No. 6, p. 1879-1888, 2020/12
  • Future Directions of Therapeutic Vaccines for Chronic Diseases., Ryo Nakamaru,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, Circulation journal : official journal of the Japanese Circulation Society, Vol. 84, No. 11, p. 1895-1902, 2020/10/23
  • Progress of Gene Therapy in Cardiovascular Disease., Munehisa Shimamura,Hironori Nakagami,Fumihiro Sanada,Ryuichi Morishita, Hypertension (Dallas, Tex. : 1979), Vol. 76, No. 4, p. 1038-1044, 2020/10
  • Antiproliferative Effects of Monoclonal Antibodies against (Pro)Renin Receptor in Pancreatic Ductal Adenocarcinoma., Asadur Rahman,Makoto Matsuyama,Akio Ebihara,Yuki Shibayama,Arif Ul Hasan,Hironori Nakagami,Fumiaki Suzuki,Jiao Sun,Tomoe Kobayashi,Hiroki Hayashi,Daisuke Nakano,Hideki Kobara,Tsutomu Masaki,Akira Nishiyama, Molecular cancer therapeutics, American Association for Cancer Research (AACR), Vol. 19, No. 9, p. 1844-1855, 2020/09
  • The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice., Shota Yoshida,Hironori Nakagami,Hiroki Hayashi,Yuka Ikeda,Jiao Sun,Akiko Tenma,Hideki Tomioka,Tomohiro Kawano,Munehisa Shimamura,Ryuichi Morishita,Hiromi Rakugi, Nature communications, Springer Science and Business Media LLC, Vol. 11, No. 1, p. 2482-2482, 2020/05/18
  • [Current status and perspectives in the development of therapeutic agents targeting post-ischemic inflammation in the acute stage of stroke]., Munehisa Shimamura,Hironori Nakagami,Tsutomu Sasaki,Ryuichi Morishita,Hideki Mochizuki, Rinsho shinkeigaku = Clinical neurology, 2020/03/31
  • Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice., Hiroshi Koriyama,Yuka Ikeda,Hironori Nakagami,Munehisa Shimamura,Shota Yoshida,Hiromi Rakugi,Ryuichi Morishita, Vaccines, Vol. 8, No. 1, 2020/02/12
  • Combined Analysis of Clinical Data on HGF Gene Therapy to Treat Critical Limb Ischemia in Japan., Ryuichi Morishita,Munehisa Shimamura,Yasushi Takeya,Hironori Nakagami,Mitsuaki Chujo,Tetsuya Ishihama,Ei Yamada,Hiromi Rakugi, Current gene therapy, BENTHAM SCIENCE PUBL LTD, Vol. 20, No. 1, p. 25-35, 2020
  • Novel properties of myoferlin in glucose metabolism via pathways involving modulation of adipose functions., Nozato Y,Takami Y,Yamamoto K,Nagasawa M,Nozato S,Imaizumi Y,Takeshita H,Cheng W,Ito Y,Takeda S,Takeya Y,Sugimoto K,Nakagami H,Hanayama R,Rakugi H, FASEB J., Vol. 34, p. 2792-2811, 2020/01
  • AJP001, a novel helper T-cell epitope, induces a humoral immune response with activation of innate immunity when included in a peptide vaccine., Akiko Tenma,Hironori Nakagami,Hideki Tomioka,Makoto Sakaguchi,Ryoko Ide,Hiroshi Koriyama,Hiroki Hayashi,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, FASEB bioAdvances, Vol. 1, No. 12, p. 760-772, 2019/12
  • Investigator-initiated clinical study of a functional peptide, SR-0379, for limb ulcers of patients with Werner syndrome as a pilot study., Hironori Nakagami,Ken Sugimoto,Takahiro Ishikawa,Masaya Koshizaka,Taku Fujimoto,Eiji Kiyohara,Misa Hayashi,Yukinobu Nakagawa,Hiroshi Ando,Yuta Terabe,Yoichi Takami,Koichi Yamamoto,Yasushi Takeya,Minoru Takemoto,Tamotsu Ebihara,Ayumi Nakamura,Mitsunori Nishikawa,Xiang Jing Yao,Hideki Hanaoka,Koutaro Yokote,Hiromi Rakugi, Geriatrics & gerontology international, Vol. 19, No. 11, p. 1118-1123, 2019/11
  • Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis., Nan Ju,Munehisa Shimamura,Hiroki Hayashi,Yuka Ikeda,Shota Yoshida,Ayumi Nakamura,Ryuichi Morishita,Hiromi Rakugi,Hironori Nakagami, Scientific reports, Vol. 9, No. 1, p. 15434-15434, 2019/10/28
  • Serum albumin/globulin ratio is associated with cognitive function in community-dwelling older people: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study., Maeda S,Takeya Y,Oguro R,Akasaka H,Ryuno H,Kabayama M,Yokoyama S,Nagasawa M,Fujimoto T,Takeda M,Onishi-Takeya M,Itoh N,Takami Y,Yamamoto K,Sugimoto K,Inagaki H,Ogawa M,Nakagawa T,Yasumoto S,Masui Y,Arai Y,Ishizaki T,Ikebe K,Gondo Y,Kamide K,Rakugi H, Geriatrics & gerontology international, Vol. 19, No. 10, p. 967-971, 2019/10
  • A vaccine targeting blood clot formation: what is the potential?, Shimamura M,Nakagami H, Expert review of vaccines, Vol. 18, No. 5, p. 419-421, 2019/05
  • Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity., Yohko Yoshida,Ippei Shimizu,Yuka Hayashi,Ryutaro Ikegami,Masayoshi Suda,Goro Katsuumi,Takayuki Wakasugi,Masaaki Nakao,Hironori Nakagami,Ryuichi Morishita,Tohru Minamino, Scientific reports, Vol. 9, No. 1, p. 3858-3858, 2019/03/07
  • Temporal and spatial profile of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in ischemic stroke in mice., Kawano T,Shimamura M,Nakagami H,Kanki H,Sasaki T,Mochizuki H, PloS one, Vol. 14, No. 5, 2019
  • Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis., Imaizumi Y,Takami Y,Yamamoto K,Nagasawa M,Nozato Y,Nozato S,Takeshita H,Wang C,Yokoyama S,Hayashi H,Hongyo K,Akasaka H,Takeya Y,Sugimoto K,Nakagami H,Rakugi H, Biochemical and biophysical research communications, Vol. 508, No. 4, p. 1168-1174, 2019/01
  • Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke., Shimamura M,Nakagami H,Shimizu H,Mukai H,Watanabe R,Okuzono T,Kawano T,Ikeda Y,Hayashi H,Yoshida S,Ju N,Mochizuki H,Morishita R, Scientific reports, Vol. 8, No. 1, 2018/12
  • Therapeutic Vaccine Against S100A9 (S100 Calcium-Binding Protein A9) Inhibits Thrombosis Without Increasing the Risk of Bleeding in Ischemic Stroke in Mice., Kawano T,Shimamura M,Nakagami H,Iso T,Koriyama H,Takeda S,Baba K,Sasaki T,Sakaguchi M,Morishita R,Mochizuki H, Hypertension (Dallas, Tex. : 1979), Vol. 72, No. 6, p. 1355-1364, 2018/12
  • Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice., Hikari Takeshita,Koichi Yamamoto,Satoko Nozato,Masao Takeda,So-Ichiro Fukada,Tadakatsu Inagaki,Hirotsugu Tsuchimochi,Mikiyasu Shirai,Yoichi Nozato,Taku Fujimoto,Yuki Imaizumi,Serina Yokoyama,Motonori Nagasawa,Go Hamano,Kazuhiro Hongyo,Tatsuo Kawai,Hiroko Hanasaki-Yamamoto,Shuko Takeda,Toshimasa Takahashi,Hiroshi Akasaka,Norihisa Itoh,Yoichi Takami,Yasushi Takeya,Ken Sugimoto,Hironori Nakagami,Hiromi Rakugi, Journal of cachexia, sarcopenia and muscle, Vol. 9, No. 5, p. 975-986, 2018/10
  • Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice., Shimamura M,Nakagami H,Shimizu H,Wakayama K,Kawano T,Ikeda Y,Hayashi H,Yoshida S,Mochizuki H,Morishita R, BioMed research international, Vol. 2018, 2018
  • Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice., Ryo Kawakami,Yoichi Nozato,Hironori Nakagami,Yuka Ikeda,Munehisa Shimamura,Shota Yoshida,Jiao Sun,Tomohiro Kawano,Yoichi Takami,Takahisa Noma,Hiromi Rakugi,Tetsuo Minamino,Ryuichi Morishita, PloS one, Vol. 13, No. 2, 2018
  • Physician-initiated clinical study of limb ulcers treated with a functional peptide, SR-0379: from discovery to a randomized, double-blind, placebo-controlled trial., Hironori Nakagami,Ken Sugimoto,Takahiro Ishikawa,Taku Fujimoto,Toshifumi Yamaoka,Misa Hayashi,Eiji Kiyohara,Hiroshi Ando,Yuta Terabe,Yoichi Takami,Koichi Yamamoto,Yasushi Takeya,Minoru Takemoto,Masaya Koshizaka,Tamotsu Ebihara,Ayumi Nakamura,Mitsunori Nishikawa,Xiang Jing Yao,Hideki Hanaoka,Ichiro Katayama,Koutaro Yokote,Hiromi Rakugi, NPJ aging and mechanisms of disease, Vol. 4, p. 2-2, 2018
  • Association between renin-angiotensin-aldosterone system blockade and future osteoporotic fracture risk in hypertensive population A population-based cohort study in Taiwan, Chang-I. Chen,Jong-Shiuan Yeh,Nai-Wen Tsao,Fen-Yen Lin,Chun-Ming Shih,Kuang-Hsing Chiang,Yung-Ta Kao,Yu-Ann Fang,Lung-Wen Tsai,Wen-Chi Liu,Hironori Nakagami,Ryuichi Morishita,Yi-Jie Kuo,Chun-Yao Huang, MEDICINE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 96, No. 46, 2017/11
  • Physician-initiated first-in-human clinical study using a novel angiogenic peptide, AG30/5C, for patients with severe limb ulcers, Hironori Nakagami,Toshifumi Yamaoka,Misa Hayashi,Atsushi Tanemura,Yasushi Takeya,Hitomi Kurinami,Ken Sugimoto,Ayumi Nakamura,Kazunori Tomono,Katsuto Tamai,Ichiro Katayama,Hiromi Rakugi,Yasufumi Kaneda, GERIATRICS & GERONTOLOGY INTERNATIONAL, WILEY, Vol. 17, No. 11, p. 2150-2156, 2017/11
  • Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes, Zhengda Pang,Akifumi Kushiyama,Jiao Sun,Takako Kikuchi,Hiroki Yamazaki,Yasuhiko Iwamoto,Hiroshi Koriyama,Shota Yoshida,Munehisa Shimamura,Masayoshi Higuchi,Tomohiro Kawano,Yoichi Takami,Hiromi Rakugi,Ryuichi Morishita,Hironori Nakagami, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 31, No. 9, p. 4053-4063, 2017/09
  • Design of therapeutic vaccines as a novel antibody therapy for cardiovascular diseases, Hironori Nakagami, JOURNAL OF CARDIOLOGY, ELSEVIER SCIENCE BV, Vol. 70, No. 3-4, p. 201-205, 2017/09
  • Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress, Kouji Wakayama,Munehisa Shimamura,Jun-ichi Suzuki,Ryo Watanabe,Hiroshi Koriyama,Hiroshi Akazawa,Hironori Nakagami,Hideki Mochizuki,Mitsuaki Isobe,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 5, p. 1362-+, 2017/05
  • A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction, Ryo Watanabe,Jun-ichi Suzuki,Kouji Wakayama,Yasuhiro Maejima,Munehisa Shimamura,Hiroshi Koriyama,Hironori Nakagami,Hidetoshi Kumagai,Yuichi Ikeda,Hiroshi Akazawa,Ryuichi Morishita,Issei Komuro,Mitsuaki Isobe, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 7, 2017/03
  • A novel lipoprotein (A) lowering drug, D-47, decreases neointima thickening after vascular injury, Yutaka Nakaya,Daiju Fukuda,Takashi Oyamada,Kazuo Ogawa,Nagakatsu Harada,Hironori Nakagami,Ryuichi Morishita,Masataka Sata,Hiroshi Sakaue, Journal of Medical Investigation, University of Tokushima, Vol. 64, No. 1-2, p. 64-67, 2017
  • Evaluating the potential of the GFAP-KLH immune-tolerizing vaccine for type 1 diabetes in mice, Zhengda Pang,Masayoshi Higuchi,Hiroshi Koriyama,Shota Yoshida,Hitomi Kurinami,Munehisa Shimamura,Yoichi Takami,Hiromi Rakugi,Ryuichi Morishita,Hironori Nakagami, FEBS LETTERS, WILEY-BLACKWELL, Vol. 591, No. 1, p. 129-136, 2017/01
  • A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke, Hitomi Kurinami,Munehisa Shimamura,Hironori Nakagami,Hideo Shimizu,Hiroshi Koriyama,Tomohiro Kawano,Kouji Wakayama,Hideki Mochizuki,Hiromi Rakugi,Ryuichi Morishita, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 6, 2016/11
  • Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor, Koichi Yamamoto,Akemi Kakino,Hikari Takeshita,Norihiro Hayashi,Lei Li,Atsushi Nakano,Hiroko Hanasaki-Yamamoto,Yoshiko Fujita,Yuki Imaizumi,Serina Toyama-Yokoyama,Chikako Nakama,Tatsuo Kawai,Masao Takeda,Kazuhiro Hongyo,Ryosuke Oguro,Yoshihiro Maekawa,Norihisa Itoh,Yoichi Takami,Miyuki Onishi,Yasushi Takeya,Ken Sugimoto,Kei Kamide,Hironori Nakagami,Mitsuru Ohishi,Theodore W. Kurtz,Tatsuya Sawamura,Hiromi Rakugi, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 29, No. 8, p. 3342-3356, 2015/08
  • Effect of angiotensinII receptor blocker, olmesartan, on turnover of bone metabolism in bedridden elderly hypertensive women with disuse syndrome, Motokuni Aoki,Hirohisa Kawahata,Daisuke Sotobayashi,Hisahiro Yu,Atsushi Moriguchi,Hironori Nakagami,Toshio Ogihara,Ryuichi Morishita, GERIATRICS & GERONTOLOGY INTERNATIONAL, WILEY-BLACKWELL, Vol. 15, No. 8, p. 1064-1072, 2015/08
  • Low alpha-synuclein levels in the blood are associated with insulin resistance, Gerardo Rodriguez-Araujo,Hironori Nakagami,Yoichi Takami,Tomohiro Katsuya,Hiroshi Akasaka,Shigeyuki Saitoh,Kazuaki Shimamoto,Ryuichi Morishita,Hiromi Rakugi,Yasufumi Kaneda, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 5, 2015/07
  • Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats, Hiroshi Koriyama,Hironori Nakagami,Futoshi Nakagami,Mariana Kiomy Osako,Mariko Kyutoku,Munehisa Shimamura,Hitomi Kurinami,Tomohiro Katsuya,Hiromi Rakugi,Ryuichi Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 66, No. 1, p. 167-174, 2015/07
  • Disease-associated polymorphisms in 9p21 are not associated with extreme longevity., Congrains A,Kamide K,Hirose N,Arai Y,Oguro R,Nakama C,Imaizumi Y,Kawai T,Kusunoki H,Yamamoto H,Onishi-Takeya M,Takeya Y,Yamamoto K,Sugimoto K,Akasaka H,Saitoh S,Miura T,Awata N,Kato N,Katsuya T,Ikebe K,Gondo Y,Rakugi H, Geriatrics & gerontology international, Vol. 15, No. 6, p. 797-803, 2015/06
  • Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse, Hirohisa Kawahata,Daisuke Sotobayashi,Motokuni Aoki,Hideo Shimizu,Hironori Nakagami,Toshio Ogihara,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 38, No. 6, p. 382-393, 2015/06
  • The Biphasic Effects of Oxidized-Low Density Lipoprotein on the Vasculogenic Function of Endothelial Progenitor Cells, Feng-Yen Lin,Nai-Wen Tsao,Chun-Ming Shih,Yi-Wen Lin,Jong-Shiua Yeh,Jaw-Wen Chen,Hironori Nakagami,Ryuichi Morishita,Tatsuya Sawamura,Chun-Yao Huang, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 10, No. 5, 2015/05
  • Evaluation of the Genetic Risk of Hypertension-Related Diseases, Hironori Nakagami, CIRCULATION JOURNAL, JAPANESE CIRCULATION SOC, Vol. 79, No. 4, p. 756-757, 2015/04
  • Development of DNA vaccines as an anti-hypertensive therapy or for anti-angiogenesis, Hironori Nakagami,Ryuichi Morishita, EXPERT OPINION ON BIOLOGICAL THERAPY, TAYLOR & FRANCIS LTD, Vol. 15, No. 3, p. 431-436, 2015/03
  • Teneligliptin: expectations for its pleiotropic action, Ryuichi Morishita,Hironori Nakagami, EXPERT OPINION ON PHARMACOTHERAPY, INFORMA HEALTHCARE, Vol. 16, No. 3, p. 417-426, 2015/02
  • Prevention of Neointimal Formation After Angioplasty Using Nuclear Factor-kappa B Decoy Oligodeoxynucleotide-Coated Balloon Catheter in Rabbit Model, Takashi Miyake,Shinya Ihara,Tetsuo Miyake,Yusuke Tsukada,Hajime Watanabe,Hiroaki Matsuda,Hideki Kiguchi,Hiroyuki Tsujimoto,Hironori Nakagami,Ryuichi Morishita, CIRCULATION-CARDIOVASCULAR INTERVENTIONS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 7, No. 6, p. 787-796, 2014/12
  • Peptide vaccines for hypertension and diabetes mellitus, Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, Vaccines, MDPI AG, Vol. 2, No. 4, p. 832-840, 2014/11/26
  • Gene therapy for peripheral arterial disease, Munehisa Shimamura,Hironori Nakagami,Yoshiaki Taniyama,Ryuichi Morishita, EXPERT OPINION ON BIOLOGICAL THERAPY, INFORMA HEALTHCARE, Vol. 14, No. 8, p. 1175-1184, 2014/08
  • [Bone metabolism and cardiovascular function update. Cross link of hypertension, bone loss and vascular calcification - common back grounds in renin angiotensin system with anti-aging aspect -]., Shimizu H,Nakagami H,Morishita R,Clinical calcium, Vol. 24, No. 7, p. 53-62, 2014/07
  • The dipeptidyl peptidase-4 inhibitor teneligliptin improved endothelial dysfunction and insulin resistance in the SHR/NDmcr-cp rat model of metabolic syndrome, Hironori Nakagami,Zhengda Pang,Takashi Shimosato,Toshinori Moritani,Hitomi Kurinami,Hiroshi Koriyama,Akiko Tenma,Munehisa Shimamura,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 37, No. 7, p. 629-635, 2014/07
  • OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice, Munehisa Shimamura,Hironori Nakagami,Mariana K. Osako,Hitomi Kurinami,Hiroshi Koriyama,Pang Zhengda,Hideki Tomioka,Akiko Tenma,Kouji Wakayama,Ryuichi Morishita, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 111, No. 22, p. 8191-8196, 2014/06
  • Long-term expression of periostin during the chronic stage of ischemic stroke in mice, Munehisa Shimamura,Yoshiaki Taniyama,Hironori Nakagami,Naruto Katsuragi,Kouji Wakayama,Hiroshi Koriyama,Hitomi Kurinami,Akiko Tenma,Hideki Tomioka,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 37, No. 6, p. 494-499, 2014/06
  • Therapeutic vaccine against DPP4 improves glucose metabolism in mice, Zhengda Pang,Hironori Nakagami,Mariana K. Osako,Hiroshi Koriyama,Futoshi Nakagami,Hideki Tomioka,Munehisa Shimamura,Hitomi Kurinami,Yoichi Takami,Ryuichi Morishita,Hiromi Rakugi, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 111, No. 13, p. E1256-E1263, 2014/04
  • Therapeutic Vaccines for Hypertension and Dyslipidemia, Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, INTERNATIONAL HEART JOURNAL, INT HEART JOURNAL ASSOC, Vol. 55, No. 2, p. 96-100, 2014/03
  • Novel Anti-Microbial Peptide SR-0379 Accelerates Wound Healing via the PI3 Kinase/Akt/mTOR Pathway, Hideki Tomioka,Hironori Nakagami,Akiko Tenma,Yoshimi Saito,Toshihiro Kaga,Toshihide Kanamori,Nao Tamura,Kazunori Tomono,Yasufumi Kaneda,Ryuichi Morishita, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 9, No. 3, 2014/03
  • Development of LC-MS/MS quantification of the novel antimicrobial peptide, SR-0379, and its pharmacokinetics in rats, Hideki Tomioka,Hironori Nakagami,Tomokazu Sano,Kazuaki Takafuji,Seiji Takashima,Yasufumi Kaneda,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Bentham Science Publishers B.V., Vol. 14, No. 1, p. 26-31, 2014
  • GEANE study group; HOMED-BP study group. Genome-wide response to antihypertensive medication using home blood pressure measurements: a pilot study nested within the HOMED-BP study., Kamide K,Asayama K,Katsuya T,Ohkubo T,Hirose T,Inoue R,Metoki H,Kikuya M,Obara T,Hanada H,Thijs L,Kuznetsova T,Noguchi Y,Sugimoto K,Ohishi M,Morimoto S,Nakahashi T,Takiuchi S,Ishimitsu T,Tsuchihashi T,Soma M,Higaki J,Matsuura H,Shinagawa T,Sasaguri T,Miki T,Takeda K,Shimamoto K,Ueno M,Hosomi N,Kato J,Komai N,Kojima S,Sase K,Miyata T,Tomoike H,Kawano Y,Ogihara T,Rakugi H,Staessen JA,Imai Y, Pharmacogenomics, 2013/11
  • Development of novel DNA vaccine for VEGF in murine cancer model, Mariko Kyutoku,Hironori Nakagami,Hiroshi Koriyama,Hideki Tomioka,Futoshi Nakagami,Munehisa Shimamura,Hitomi Kurinami,Pang Zhengda,Dong Hyun Jo,Jeong Hun Kim,Nobuyuki Takakura,Ryuichi Morishita, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 3, 2013/11
  • Unique remodeling processes after vascular injury in intracranial arteries: analysis using a novel mouse model, Munehisa Shimamura,Hironori Nakagami,Masataka Sata,Minoru Takaoka,Junya Azuma,Mariana Kiomy Osako,Hiroshi Koriyama,Hitomi Kurinami,Kouji Wakayama,Takashi Miyake,Ryuichi Morishita, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, NATURE PUBLISHING GROUP, Vol. 33, No. 8, p. 1153-1159, 2013/08
  • Do Angiotensin Receptor Blockers Protect Against Alzheimer's Disease?, Hitomi Kurinami,Munehisa Shimamura,Naoyuki Sato,Hironori Nakagami,Ryuichi Morishita, DRUGS & AGING, ADIS INT LTD, Vol. 30, No. 6, p. 367-372, 2013/06
  • Cross-Talk of Receptor Activator of Nuclear Factor-kappa B Ligand Signaling With Renin-Angiotensin System in Vascular Calcification, Mariana Kiomy Osako,Hironori Nakagami,Munehisa Shimamura,Hiroshi Koriyama,Futoshi Nakagami,Hideo Shimizu,Takashi Miyake,Masao Yoshizumi,Hiromi Rakugi,Ryuichi Morishita, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 33, No. 6, p. 1287-+, 2013/06
  • Potential Effect of Angiotensin II Receptor Blockade in Adipose Tissue and Bone, Hironori Nakagami,Mariana Kiomy Osako,Ryuichi Morishita, CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBL LTD, Vol. 19, No. 17, p. 3049-3053, 2013/05
  • Inhibition of Neointima Formation through DNA Vaccination for Apolipoprotein(a): A New Therapeutic Strategy for Lipoprotein(a), Mariko Kyutoku,Hironori Nakagami,Hiroshi Koriyama,Futoshi Nakagami,Munehisa Shimamura,Hitomi Kurinami,Hideki Tomioka,Takashi Miyake,Tomohiro Katsuya,Ryuichi Morishita, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 3, 2013/04
  • [Hypertension and osteoporosis]., Nakagami H,Morishita R,Clinical calcium, Vol. 23, No. 4, p. 497-503, 2013/04
  • The mechanism of white and brown adipocyte differentiation, Hironori Nakagami, Diabetes and Metabolism Journal, Vol. 37, No. 2, p. 85-90, 2013/04
  • Human gene therapy in cardiovascular diseases, Mariana Kiomy Osako,Hironori Nakagami,Ryuichi Morishita, Gene Therapy: Technologies and Applications, Future Medicine Ltd., p. 85-93, 2013/03/01
  • Decrease in Blood Pressure and Regression of Cardiovascular Complications by Angiotensin II Vaccine in Mice, Futoshi Nakagami,Hiroshi Koriyama,Hironori Nakagami,Mariana Kiomy Osako,Munehisa Shimamura,Mariko Kyutoku,Takashi Miyake,Tomohiro Katsuya,Hiromi Rakugi,Ryuichi Morishita, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 8, No. 3, 2013/03
  • Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway, Gerardo Rodriguez-Araujo,Hironori Nakagami,Hiroki Hayashi,Masaki Mori,Tetsuya Shiuchi,Yasuhiko Minokoshi,Yoshikazu Nakaoka,Yoichi Takami,Issei Komuro,Ryuichi Morishita,Yasufumi Kaneda, Cellular and Molecular Life Sciences, Vol. 70, No. 6, p. 1123-1133, 2013/03
  • The Transcription Factors Tbx18 and Wt1 Control the Epicardial Epithelial-Mesenchymal Transition through Bi-Directional Regulation of Slug in Murine Primary Epicardial Cells, Makiko Takeichi,Keisuke Nimura,Masaki Mori,Hironori Nakagami,Yasufumi Kaneda, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 8, No. 2, 2013/02
  • Olmesartan reduces pentosidine production and ameliorates fragility of bone in ovariectomized fructose-fed rats, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Osako Kiomy Mariana,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 13, No. 2, p. 150-158, 2013
  • Lymphedema and Therapeutic Lymphangiogenesis, Yukihiro Saito,Hironori Nakagami,Yasufumi Kaneda,Ryuichi Morishita, BIOMED RESEARCH INTERNATIONAL, HINDAWI PUBLISHING CORPORATION, Vol. 2013, 2013
  • Gene Therapy and Cell-Based Therapies for Therapeutic Angiogenesis in Peripheral Artery Disease, Munehisa Shimamura,Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, BIOMED RESEARCH INTERNATIONAL, HINDAWI PUBLISHING CORPORATION, Vol. 2013, 2013
  • Therapeutic Effect of Ribbon-Type Nuclear Factor-kappa B Decoy Oligonucleotides in a Rat Model of Inflammatory Bowel Disease, Kazunari Ozaki,Hirofumi Makino,Motokuni Aoki,Takashi Miyake,Natsuki Yasumasa,Mariana Kiomy Osako,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, CURRENT GENE THERAPY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 6, p. 484-492, 2012/12
  • Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells, Chun-Yao Huang,Chun-Ming Shih,Nai-Wen Tsao,Yi-Wen Lin,Po-Hsun Huang,Shinn-Chih Wu,Ai-Wei Lee,Yung-Ta Kao,Nen-Chung Chang,Hironori Nakagami,Ryuichi Morishita,Keng-Liang Ou,Wen-Chi Hou,Cheng-Yen Lin,Kuo-Gi Shyu,Feng-Yen Lin, BRITISH JOURNAL OF PHARMACOLOGY, WILEY, Vol. 167, No. 7, p. 1506-1519, 2012/12
  • Moderate to High Concentrations of High-Density Lipoprotein From Healthy Subjects Paradoxically Impair Human Endothelial Progenitor Cells and Related Angiogenesis by Activating Rho-Associated Kinase Pathways, Chun-Yao Huang,Feng-Yen Lin,Chun-Ming Shih,Heng-Kien Au,Yu-Jia Chang,Hironori Nakagami,Ryuichi Morishita,Nen-Chung Chang,Kou-Gi Shyu,Jaw-Wen Chen, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 32, No. 10, p. 2405-2417, 2012/10
  • [Activation of osteoclasts by RAAS and strategy of target therapy on bone metabolic diseases]., Shimizu H,Nakagami H,Morishita R,Nihon rinsho,Japanese journal of clinical medicine, Vol. 70, No. 9, p. 1524-1529, 2012/09
  • Nucleic Acid Drugs for Preventing Restenosis after Coronary Revascularization, Takashi Miyake,Hironori Nakagami,Ryuichi Morishita, CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 15, p. 1613-1620, 2012/08
  • Modification of Decoy Oligodeoxynucleotides to Achieve the Stability and Therapeutic Efficacy, Mariana Kiomy Osako,Hironori Nakagami,Ryuichi Morishita, CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 15, p. 1603-1607, 2012/08
  • Development of Nucleic Acid Drugs for Neurological Disorders, Munehisa Shimamura,Naoyuki Sato,Hironori Nakagami,Yoshiaki Taniyama,Ryuichi Morishita, CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 15, p. 1621-1629, 2012/08
  • Modification of a novel angiogenic peptide, AG30, for the development of novel therapeutic agents, Hironori Nakagami,Tomoyuki Nishikawa,Nao Tamura,Akito Maeda,Hajime Hibino,Masayoshi Mochizuki,Takashi Shimosato,Toshinori Moriya,Ryuichi Morishita,Katsuto Tamai,Kazunori Tomono,Yasufumi Kaneda, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, WILEY-BLACKWELL, Vol. 16, No. 7, p. 1629-1639, 2012/07
  • HIG1, a novel regulator of mitochondrial gamma-secretase, maintains normal mitochondrial function, Hiroki Hayashi,Hironori Nakagami,Makiko Takeichi,Munehisa Shimamura,Nobutaka Koibuchi,Eiji Oiki,Naoyuki Sato,Hiroshi Koriyama,Masaki Mori,Rodriguez Gerardo Araujo,Akito Maeda,Ryuichi Morishita,Katsuto Tamai,Yasufumi Kaneda, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 26, No. 6, p. 2306-2317, 2012/06
  • Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells, Masaki Mori,Hironori Nakagami,Gerardo Rodriguez-Araujo,Keisuke Nimura,Yasufumi Kaneda, PLOS BIOLOGY, PUBLIC LIBRARY SCIENCE, Vol. 10, No. 4, 2012/04
  • Role of Central Nervous System Periostin in Cerebral Ischemia, Munehisa Shimamura,Yoshiaki Taniyama,Naruto Katsuragi,Nobutaka Koibuchi,Mariko Kyutoku,Naoyuki Sato,Mohammad Allahtavakoli,Kouji Wakayama,Hironori Nakagami,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 4, p. 1108-U341, 2012/04
  • Development and Modification of Decoy Oligodeoxynucleotides for Clinical Application, Mariana Kiomy Osako,Hironori Nakagami,Ryuichi Morishita, NUCLEIC ACID DRUGS, SPRINGER-VERLAG BERLIN, Vol. 249, p. 49-59, 2012
  • Links Between Hypertension and Osteoporosis: Benidipine Ameliorates Osteoporosis in Ovariectomized Hypertensive Rats Through Promotion of Osteoblast Proliferation and Inhibition of Osteoclast Differentiation, Shimizu H,Nakagami H,Yasumasa N,Mariana O.K,Kyutoku M,Koriyama H,Nakagami F,Shimamura M,Rakugi H,Morishita R, Current Cardiovascular Risk Reports, Vol. 6, No. 4, p. 274-280, 2012
  • Nifedipine prevents hepatic fibrosis in a non-alcoholic steatohepatitis model induced by an L-methionine-and choline-deficient diet, Hironori Nakagami,Munehisa Shimamura,Takashi Miyake,Takashi Shimosato,Noriko Minobe,Toshinori Moritani,Mariana Kiomy Osako,Futoshi Nakagami,Hiroshi Koriyama,Mariko Kyutoku,Hideo Shimizu,Tomohiro Katsuya,Ryuichi Morishita, MOLECULAR MEDICINE REPORTS, SPANDIDOS PUBL LTD, Vol. 5, No. 1, p. 37-40, 2012/01
  • Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Osako Kiomy Mariana,Mariko Kyutoku,Hiroshi Koriyama,Futoshi Nakagami,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 35, No. 1, p. 77-81, 2012/01
  • Salt-inducible kinase 1 influences Na(+),K(+)-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure., Popov S,Silveira A,Wågsäter D,Takemori H,Oguro R,Matsumoto S,Sugimoto K,Kamide K,Hirose T,Satoh M,Metoki H,Kikuya M,Ohkubo T,Katsuya T,Rakugi H,Imai Y,Sanchez F,Leosdottir M,Syvänen AC,Hamsten A,Melander O,Bertorello AM, Journal of hypertension, 12, Vol. 29, No. 12, p. 2395-2403, 2011/12
  • Critical Roles of Cold Shock Domain Protein A as an Endogenous Angiogenesis Inhibitor in Skeletal Muscle, Yukihiro Saito,Hironori Nakagami,Nobuyoshi Azuma,Satoshi Hirata,Fumihiro Sanada,Yoshiaki Taniyama,Ryuichi Morishita,Yasufumi Kaneda,Tadahiro Sasajima, ANTIOXIDANTS & REDOX SIGNALING, MARY ANN LIEBERT INC, Vol. 15, No. 8, p. 2109-2120, 2011/10
  • Irbesartan improves endothelial dysfunction, abnormal lipid profile, proteinuria and liver dysfunction in Zucker diabetic fatty rats independent of glucose and insulin levels, Munehisa Shimamura,Hironori Nakagami,Takashi Shimosato,Toshinori Moritani,Futoshi Nakagami,Mariana Kiomy Osako,Takashi Miyake,Hiroshi Koriyama,Hideo Shimizu,Ryuichi Morishita, EXPERIMENTAL AND THERAPEUTIC MEDICINE, SPANDIDOS PUBL LTD, Vol. 2, No. 5, p. 957-961, 2011/09
  • Can Forkhead Box P1 be a novel therapeutic target for atherosclerosis?, Hironori Nakagami,Ryuichi Morishita, ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Vol. 218, No. 1, p. 26-27, 2011/09
  • [The cutting-edge of medicine; anti-aging and cardiovascular diseases]., Nakagami H,Morishita R,Nihon Naika,Gakkai,zasshi. The Journal of,the,Japanese,Society of Internal,Medicine, Vol. 100, No. 6, p. 1677-1682, 2011/06
  • [Hypertension, CKD and bone metabolism]., Nakagami H,Morishita R,Clinical calcium, Vol. 21, No. 5, p. 685-689, 2011/05
  • Association of (pro)renin receptor gene polymorphisms with lacunar infarction and left ventricular hypertrophy in Japanese women: the Ohasama study., Hirose T,Hashimoto M,Totsune K,Metoki H,Hara A,Satoh M,Kikuya M,Ohkubo T,Asayama K,Kondo T,Kamide K,Katsuya T,Ogihara T,Izumi S,Rakugi H,Takahashi K,Imai Y, Hypertension research : official journal of the Japanese Society of Hypertension, 4, Vol. 34, p. 530-535, 2011/04
  • Obesity and Gastrointestinal Hormones-Dual Effect of Angiotensin II Receptor Blockade and a Partial Agonist of PPAR-gamma, Hironori Nakagami,Ryuichi Morishita, CURRENT VASCULAR PHARMACOLOGY, BENTHAM SCIENCE PUBL LTD, Vol. 9, No. 2, p. 162-166, 2011/03
  • [Common molecular mechanism of osteoporosis and vascular diseases]., Hironori Nakagami,Mariana Kiomy Osako,Hideo Shimizu,Hiromi Rakugi,Ryuichi Morishita, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, Vol. 48, No. 2, p. 146-8, 2011
  • Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor kappa B and Ets Prevents Abdominal Aortic Aneurysm in Rat Model, Takashi Miyake,Motokuni Aoki,Mariana K. Osako,Munehisa Shimamura,Hironori Nakagami,Ryuichi Morishita, MOLECULAR THERAPY, NATURE PUBLISHING GROUP, Vol. 19, No. 1, p. 181-187, 2011/01
  • New Concept of Vascular Calcification and Metabolism, Hironori Nakagami,Mariana K. Osako,Ryuichi Morishita, CURRENT VASCULAR PHARMACOLOGY, BENTHAM SCIENCE PUBL LTD, Vol. 9, No. 1, p. 124-127, 2011/01
  • Cold shock domain protein A (CSDA) overexpression inhibits tumor growth and lymph node metastasis in a mouse model of squamous cell carcinoma, Goichi Matsumoto,Nobuyuki Yajima,Hiroyuki Saito,Hironori Nakagami,Yasushi Omi,Ushaku Lee,Yasufumi Kaneda, CLINICAL & EXPERIMENTAL METASTASIS, SPRINGER, Vol. 27, No. 7, p. 539-547, 2010/10
  • Prevention and regression of non-alcoholic steatohepatitis (NASH) in a rat model by metabosartan, telmisartan, Hironori Nakagami,Mariana Kiomy Osako,Futoshi Nakagami,Takashi Shimosato,Noriko Minobe,Toshinori Moritani,Munehisa Shimamura,Takashi Miyake,Hideo Shimizu,Yasushi Takeya,Ryuichi Morishita, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS PUBL LTD, Vol. 26, No. 4, p. 477-481, 2010/10
  • Estrogen Inhibits Vascular Calcification via Vascular RANKL System Common Mechanism of Osteoporosis and Vascular Calcification, Mariana Kiomy Osako,Hironori Nakagami,Nobutaka Koibuchi,Hideo Shimizu,Futoshi Nakagami,Hiroshi Koriyama,Munehisa Shimamura,Takashi Miyake,Hiromi Rakugi,Ryuichi Morishita, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 107, No. 4, p. 466-U57, 2010/08
  • Inorganic polyphosphate differentiates human mesenchymal stem cells into osteoblastic cells, Daiki Morimoto,Tetsuya Tomita,Shoko Kuroda,Chikahisa Higuchi,Shinichi Kato,Toshikazu Shiba,Hironori Nakagami,Ryuichi Morishita,Hideki Yoshikawa, JOURNAL OF BONE AND MINERAL METABOLISM, SPRINGER TOKYO, Vol. 28, No. 4, p. 418-423, 2010/07
  • Estrogen attenuates vascular remodeling in Lp(a) transgenic mice, Futoshi Nakagami,Hironori Nakagami,Mariana Kiomy Osako,Masaaki Iwabayashi,Yoshiaki Taniyama,Takefumi Doi,Hideo Shimizu,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Vol. 211, No. 1, p. 41-47, 2010/07
  • Variation in OSBPL10 is associated with dyslipidemia, Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Hiroshi Akasaka,Shigeyuki Saitoh,Kazuaki Shimamoto,Toshio Ogihara,Yasufumi Kaneda,Ryuichi Morishita,Hiromi Rakugi, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 33, No. 5, p. 511-514, 2010/05
  • Effect of an Antimicrobial Agent on Atherosclerotic Plaques Assessment of Metalloproteinase Activity by Molecular Imaging, Satoru Ohshima,Shinichiro Fujimoto,Artiom Petrov,Hironori Nakagami,Nezam Haider,Jun Zhou,Nobuhiro Tahara,Mariana Kiomy Osako,Ai Fujimoto,Jie Zhu,Toyoaki Murohara,D. Scott Edwards,Navneet Narula,Nathan D. Wong,Y. Chandrashekhar,Ryuichi Morishita,Jagat Narula, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, Vol. 55, No. 12, p. 1240-1249, 2010/03
  • Accumulation of common polymorphisms is associated with development of hypertension:a 12-year follow-up from the Ohasama study., Watanabe Y,Metoki H,Ohkubo T,Katsuya T,Tabara Y,Kikuya M,Hirose T,Sugimoto K,Asayama K,Inoue R,Hara A,Obara T,Nakura J,Kohara K,Totsune K,Ogihara T,Rakugi H,Miki T,Imai Y, Hypertension Research, Vol. 33, No. 2, p. 129-134, 2010/02
  • Gene Therapy Toward Clinical Application in the Cardiovascular Field, Hironori Nakagami,Mariana Kiomy Osako,Ryuichi Morishita, Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging, Oxford University Press, 2010/01/01
  • Anti-Aging Medicine in Cardiovascular Disease, Morishita Ryuichi,Komuro Issei,Horiuchi Masatsugu,Nakagami Hironori,Minamino Toru,Higashi Yukihito, Anti-Aging Med, Japanese Society of Anti-Aging Medicine, Vol. 7, No. 5, p. 45-49, 2010
  • Identification of Evidence Suggestive of an Association with Peripheral Arterial Disease at the OSBPL10 Locus by Genome-Wide Investigation in the Japanese Population, Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Ken Sugimoto,Hidetoshi Yamashita,Yoichi Takami,Shiro Maeda,Michiaki Kubo,Atsushi Takahashi,Yusuke Nakamura,Toshio Ogihara,Hiromi Rakugi,Yasufumi Kaneda,Ryuichi Morishita, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, JAPAN ATHEROSCLEROSIS SOC, Vol. 17, No. 10, p. 1054-1062, 2010
  • Priming With Angiopoietin-1 Augments the Vasculogenic Potential of the Peripheral Blood Stem Cells Mobilized With Granulocyte Colony-Stimulating Factor Through a Novel Tie2/Ets-1 Pathway, Min-Seok Kim,Choon-Soo Lee,Jin Hur,Hyun-Jai Cho,Soo-In Jun,Tae-Youn Kim,Sae-Won Lee,Jung-Won Suh,Kyung-Woo Park,Hae-Young Lee,Hyun-Jae Kang,Dong-Soo Lee,Gou-Young Koh,Hironori Nakagami,Ryuichi Morishita,Young-Bae Park,Hyo-Soo Kim, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 120, No. 22, p. 2240-U150, 2009/12
  • Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive rats, Hideo Shimizu,Hironori Nakagami,Mariana Kiomy Osako,Futoshi Nakagami,Yasuo Kunugiza,Tetsuya Tomita,Hideki Yoshikawa,Hiromi Rakugi,Toshio Ogihara,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 32, No. 9, p. 786-790, 2009/09
  • New Treatment of Periodontal Diseases by Using NF-kappa B Decoy Oligodeoxynucleotides via Prevention of Bone Resorption and Promotion of Wound Healing, Hideo Shimizu,Hironori Nakagami,Shosuke Morita,Ikuyo Tsukamoto,Mariana Kiomy Osako,Futoshi Nakagami,Takashi Shimosato,Noriko Minobe,Ryuichi Morishita, ANTIOXIDANTS & REDOX SIGNALING, MARY ANN LIEBERT, INC, Vol. 11, No. 9, p. 2065-2075, 2009/09
  • [Hormones and osteoporosis update. Effect of angiotensin II on bone metabolism]., Nakagami H,Morishita R,Clinical calcium, Vol. 19, No. 7, p. 997-1002, 2009/07
  • [Gene therapy for anti-aging medicine]., Nakagami H,Morishita R,Nihon rinsho,Japanese journal of clinical medicine, Vol. 67, No. 7, p. 1407-1411, 2009/07
  • Zyxin Mediates Actin Fiber Reorganization in Epithelial-Mesenchymal Transition and Contributes to Endocardial Morphogenesis, Masaki Mori,Hironori Nakagami,Nobutaka Koibuchi,Koichi Miura,Yoichi Takami,Hiroshi Koriyama,Hiroki Hayashi,Hisataka Sabe,Naoki Mochizuki,Ryuichi Morishita,Yasufumi Kaneda, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 20, No. 13, p. 3115-3124, 2009/07
  • FHL-2 Suppresses VEGF-Induced Phosphatidylinositol 3-Kinase/Akt Activation via Interaction With Sphingosine Kinase-1, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Hiroshi Koriyama,Masaki Mori,Katsuto Tamai,Jianxin Sun,Kaori Nagao,Ryuichi Morishita,Yasufumi Kaneda, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 29, No. 6, p. 909-U331, 2009/06
  • Fluvastatin improves osteoporosis in fructose-fed insulin resistant model rats through blockade of the classical mevalonate pathway and antioxidant action, Rie Hanayam,Hideo Shimizu,Hironori Nakagami,Mariana Kiomy Osako,Hirofumi Makino,Yasuo Kunugiza,Tetsuya Tomita,Ikuyo Tsukamoto,Hideki Yoshikawa,Hiromi Rakugi,Ryuchi Morishita, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS PUBL LTD, Vol. 23, No. 5, p. 581-588, 2009/05
  • Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study., Hirose T,Hashimoto M,Totsune K,Metoki H,Asayama K,Kikuya M,Sugimoto K,Katsuya T,Ohkubo T,Hashimoto J,Rakugi H,Takahashi K,Imai Y, American journal of hypertension, 3, Vol. 22, p. 294-299, 2009/03
  • Vascular protective effects of ezetimibe in ApoE-deficient mice, Hironori Nakagami,Mariana Kiomy Osako,Yoichi Takami,Rie Hanayama,Hiroshi Koriyama,Masaki Mori,Hiroki Hayashi,Hideo Shimizu,Ryuichi Morishita, ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Vol. 203, No. 1, p. 51-58, 2009/03
  • Development of a novel antimicrobial peptide, AG-30, with angiogenic properties, Tomoyuki Nishikawa,Hironori Nakagami,Akito Maeda,Ryuichi Morishita,Nobuhiko Miyazaki,Toshihiro Ogawa,Yasuhiko Tabata,Yasushi Kikuchi,Hiroki Hayashi,Yoshiro Tatsu,Noboru Yumoto,Katsuto Tamai,Kazunori Tomono,Yasufumi Kaneda, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, WILEY-BLACKWELL PUBLISHING, INC, Vol. 13, No. 3, p. 535-546, 2009/03
  • PITAVASTATIN SUPPRESSES FORMATION AND PROGRESSION OF CEREBRAL ANEURYSMS THROUGH INHIBITION OF THE NUCLEAR FACTOR kappa B PATHWAY, Tomohiro Aoki,Hiroharu Kataoka,Ryota Ishibashi,Hironori Nakagami,Kazuhiko Nozaki,Ryuuichi Morishita,Nobuo Hashimoto, NEUROSURGERY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 64, No. 2, p. 357-365, 2009/02
  • Cold shock domain protein A, novel endogenous regulator of angiogenesis in heart, Yukihiro Saito,Hironori Nakagami,Nobuyoshi Azuma,Ryuichi Morishita,Yasufumi Kaneda,Tadahiro Sasajima, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 45, No. 4, p. S7-S8, 2008/10
  • Differential response of vascular hepatocyte growth factor concentration and lipid accumulation between telmisartan and losartan in ApoE-deficient mice, Hironori Nakagami,Mariana Kiomy Osako,Yoichi Takami,Rie Hanayama,Hiroshi Koriyama,Masaki Mori,Hiroki Hayashi,Hideo Shimizu,Ryuichi Morishita, MOLECULAR MEDICINE REPORTS, SPANDIDOS PUBL LTD, Vol. 1, No. 5, p. 657-661, 2008/09
  • Angiotensin II accelerates osteoporosis by activating osteoclasts, Hideo Shimizu,Hironori Nakagami,Mariana Kiomy Osako,Rie Hanayama,Yasuo Kunugiza,Takuji Kizawa,Tetsuya Tomita,Hideki Yoshikawa,Toshio Ogihara,Ryuichi Morishita, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 22, No. 7, p. 2465-2475, 2008/07
  • Pleiotropic effect of statins as antioxidants on cardiac hypertrophy, Hironori Nakagami,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 8, No. 2, p. 167-171, 2008/06
  • Identification of angiogenic and antimicrobial factor, AG-30, and analysis of its De Novo engineered variants, Tomoyuki Nishikawa,Hironori Nakagami,Akito Maeda,Nobuhiko Miyazaki,Yasuhiko Tabata,Ryuichi Morishita,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 10, No. 4, p. 473-473, 2008/04
  • Potential role of CYLD (cylindromatosis) as a deubiquitinating enzyme in vascular cells, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Hiroki Hayashi,Masaki Mori,Hiroshi Koriyama,Yoshichika Baba,Osamu Yasuda,Hiromi Rakugi,Toshio Ogihara,Yasufumi Kaneda, AMERICAN JOURNAL OF PATHOLOGY, AMER SOC INVESTIGATIVE PATHOLOGY, INC, Vol. 172, No. 3, p. 818-829, 2008/03
  • Cold shock domain protein A represses angiogenesis and lymphangiogenesis via inhibition of serum response element, Y. Saito,H. Nakagami,M. Kurooka,Y. Takami,Y. Kikuchi,H. Hayashi,T. Nishikawa,K. Tamai,R. Morishita,N. Azuma,T. Sasajima,Y. Kaneda, ONCOGENE, NATURE PUBLISHING GROUP, Vol. 27, No. 13, p. 1821-1833, 2008/03
  • NFκB decoy oligodeoxynucleotide-based therapy in cardiovascular diseases, H. Nakagami,M. K. Osako,N. Tomita,R. Morishita, RNA Technologies in Cardiovascular Medicine and Research, Springer-Verlag Berlin Heidelberg, p. 299-309, 2008
  • NF-kappa B is a key mediator of cerebral aneurysm formation, Tomohiro Aoki,Hiroharu Kataoka,Munehisa Shimamura,Hironori Nakagami,Kouji Wakayama,Takuya Moriwaki,Ryota Ishibashi,Kazuhiko Nozaki,Ryuichi Morishita,Nobuo Hashimoto, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 116, No. 24, p. 2830-2840, 2007/12
  • Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension, Hironori Nakagami,Yasushi Kikuchi,Tomohiro Katsuya,Ryuichi Morishita,Hiroshi Akasaka,Shigeyuki Saitoh,Hiromi Rakugi,Yasufumi Kaneda,Kazuaki Shimamoto,Toshio Ogihara, HYPERTENSION RESEARCH, JAPANESE SOC HYPERTENSION CENT ACADEMIC SOC, PUBL OFFICE, Vol. 30, No. 12, p. 1239-1246, 2007/12
  • Involvement of gamma-secretase in postnatal angiogenesis, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Naoyuki Sato,Yukihiro Saito,Tomoyuki Nishikawa,Masaki Mori,Hiroshi Koriyama,Katsuto Tamai,Ryuichi Morishita,Yasufumi Kaneda, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 363, No. 3, p. 584-590, 2007/11
  • Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappa B activation, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Tai-Xing Cui,Tomonaga Ichikawa,Yukihiro Saito,Hiroki Hayashi,Yasushi Kikuchi,Tomoyuki Nishikawa,Yoshichika Baba,Osamu Yasuda,Hiromi Rakugi,Toshio Ogihara,Yasufumi Kaneda, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 27, No. 10, p. 2184-2190, 2007/10
  • Recent progress in therapeutic angiogenesis., Nakagami H,Morishita R,International journal of,biomedical science,IJBS, v, Vol. 3, No. 3, p. 153-158, 2007/09
  • Increase in nuclease resistance and incorporation of NF-kappa B decoy oligodeoxynucteotides by modification of the 3 '-terminus, Mariana Kiomy Osako,Naruya Abstract Tomita,Hironori Nakagami,Yasuo Kunugiza,Masafumi Yoshino,Kazuhiko Yuyama,Tetsuya Tomita,Hideki Be Specific To The Target Transcription Fac,Toshio Ogihara,Ryuichi Morishita, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 9, No. 9, p. 812-819, 2007/09
  • Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis, Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Yoichi Takami,Yasushi Kikuchi,Hiroki Hayashi,Tomoyuki Nishikawa,Katsuto Tamai,Nobuyoshi Azuma,Tadahiro Sasajima,Yasufumi Kaneda, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 114, No. 11, p. 1177-1184, 2006/09
  • Novel drug delivery system by surface modified magnetic nanoparticles, Shin-ichi Takeda,Bungo Terazono,Fumihito Mishima,Hironori Nakagami,Shigehiro Nishijima,Yasufumi Kaneda, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, AMER SCIENTIFIC PUBLISHERS, Vol. 6, No. 9-10, p. 3269-3276, 2006/09
  • [Endothelial cell growth inhibitory gene]., Nakagami H,Kaneda T,Nihon rinsho,Japanese journal of clinical medicine,Suppl, Vol. 64 Suppl 5, p. 428-431, 2006/07
  • Model of vasculogenesis from embryonic stem cells for vascular research and regenerative medicine, Hironori Nakagami,Namika Nakagawa,Yasushi Takeya,Katsunobu Kashiwagi,Chisato Ishida,Shin-ichiro Hayashi,Motokuni Aoki,Kunio Matsumoto,Toshikazu Nakamura,Toshio Ogihara,Ryuichi Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 1, p. 112-119, 2006/07
  • NF kappa B decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts, H Shimizu,H Nakagami,Tsukamoto, I,S Morita,Y Kunugiza,T Tomita,H Yoshikawa,Y Kaneda,T Ogihara,R Morishita, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 13, No. 12, p. 933-941, 2006/06
  • Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4, F Xiang,Y Sakata,L Cui,JM Youngblood,H Nakagami,JK Liao,RL Liao,MT Chin, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 290, No. 5, p. H1997-H2006, 2006/05
  • Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector, T Nishikawa,H Nakagami,A Matsuki,A Maeda,CY Yo,T Harada,R Morishita,K Tamai,Y Kaneda, HUMAN GENE THERAPY, MARY ANN LIEBERT INC, Vol. 17, No. 4, p. 470-475, 2006/04
  • Anti-oxidant gene therapy by NF kappa B decoy oligodeoxynucleotide, Hironori Nakagami,Naruya Tomita,Yasufumi Kaneda,Toshio Ogihara,Ryuichi Morishita, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, BENTHAM SCIENCE PUBL LTD, Vol. 7, No. 2, p. 95-100, 2006/04
  • Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy, H Nakagami,R Morishita,K Maeda,Y Kikuchi,T Ogihara,Y Kaneda, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, JAPAN ATHEROSCLEROSIS SOC, Vol. 13, No. 2, p. 77-81, 2006/04
  • Application of NFkB decoy oligonucleotides to bone metabolic diseases - in vitro and in vivo studies, H. Shimizu,H. Nakagami,S. Morita,N. Yasumasa,R. Hanayama,T. Ogihara,R. Morishita, PROCEEDINGS OF THE XVIII CONGRESS OF THE EUROPEAN ASSOCIATION FOR CRANIO-MAXILLO FACIAL SURGERY, MEDIMOND S R L, p. 165-+, 2006
  • Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells, H Nakagami,K Maeda,R Morishita,S Iguchi,T Nishikawa,Y Takami,Y Kikuchi,Y Saito,K Tamai,T Ogihara,Y Kaneda, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 25, No. 12, p. 2542-2547, 2005/12
  • Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector, N Morishita,H Nakagami,R Morishita,S Takeda,F Mishima,B Terazono,S Nishijima,Y Kaneda,N Tanaka, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 334, No. 4, p. 1121-1126, 2005/09
  • Hepatocyte growth factor as potential cardiovascular therapy, Hironori Nakagami,Yasufumi Kaneda,Toshio Ogihara,Ryuichi Morishita, Expert Review of Cardiovascular Therapy, Vol. 3, No. 3, p. 513-519, 2005/05
  • Fundamental Study on Gene Therapy Utilizing Ferromagnetic Nanoparticles, Yoko Akiyama,Bungo Terazono,Fumihito Mishima,Shin-ichi Takeda,Yoshinobu Izumi,Kimiko Ema,Hironori Nakagami,Yasushi Kaneda,Shigehiro Nishijima, Abstract Book of 3rd International Symposium of 21stCentury COE "Towards Creating New Industries Based on Inter-Nanoscience"2005,p.107-108., 2005/03
  • Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis., Nakagami H,Kaneda Y,Ogihara T,Morishita R,Current diabetes reviews, Vol. 1, No. 1, p. 59-63, 2005/02
  • Hypoxia-induced renal epithelial cell death through caspase-dependent pathway: Role of Bcl-2, Bcl-xL and Bax in tubular injury, K Yamamoto,N Tomita,S Yoshimura,H Nakagami,Y Taniyama,K Yamasaki,T Ogihara,R Morishita, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS PUBL LTD, Vol. 14, No. 4, p. 633-640, 2004/10
  • Statins and myocardial hypertrophy, H Nakagami,JK Liao, CORONARY ARTERY DISEASE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 15, No. 5, p. 247-250, 2004/08
  • Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells, H Nakagami,R Morishita,T Nishikawa,H Shimizu,S Iguchi,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, HYPERTENSION RESEARCH, JAPANESE SOC HYPERTENSION CENT ACADEMIC SOC, PUBL OFFICE, Vol. 27, No. 5, p. 359-365, 2004/05
  • No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice, A Matsuki,S Yamamoto,H Nakagami,M Aoki,K Tamai,K Matsumoto,T Nakamura,T Ogihara,Y Kaneda,R Morishita, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 315, No. 1, p. 59-65, 2004/02
  • NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy, H Nakagami,M Takemoto,JK Liao, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 35, No. 7, p. 851-859, 2003/07
  • A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterol-independent mechanisms, H Nakagami,KS Jensen,JK Liao, ANNALS OF MEDICINE, ROYAL SOC MEDICINE PRESS LTD, Vol. 35, No. 6, p. 398-403, 2003
  • HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model, M Nakabayashi,R Morishita,H Nakagami,K Kuba,K Matsumoto,T Nakamura,Y Tano,Y Kaneda, DIABETOLOGIA, SPRINGER-VERLAG, Vol. 46, No. 1, p. 115-123, 2003/01
  • Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation, M Horiuchi,TX Cui,Z Li,JM Li,H Nakagami,M Iwai, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 107, No. 1, p. 106-112, 2003/01
  • Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2, Y Sakata,CN Kamei,H Nakagami,R Bronson,JK Liao,MT Chin, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 99, No. 25, p. 16197-16202, 2002/12
  • Angiotensin II subtype 2 receptor activation inhibits insulin-induced phosphoinositide 3-kinase and Akt and induces apoptosis in PC12W cells, TX Cui,H Nakagami,C Nahmias,T Shiuchi,Y Takeda-Matsubara,JM Li,L Wu,M Iwai,M Horiuchi, MOLECULAR ENDOCRINOLOGY, ENDOCRINE SOC, Vol. 16, No. 9, p. 2113-2123, 2002/09
  • ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO, T Shiuchi,TX Cui,L Wu,H Nakagami,Y Takeda-Matsubara,M Iwai,M Horiuchi, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 40, No. 3, p. 329-334, 2002/09
  • Role of angiotensin II-regulated apoptosis through distinct AT(1) and AT(2) receptors in neointimal formation, J Suzuki,M Iwai,H Nakagami,L Wu,R Chen,T Sugaya,M Hamada,K Hiwada,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 7, p. 847-853, 2002/08
  • Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,K Yamasaki,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, DIABETES, AMER DIABETES ASSOC, Vol. 51, No. 8, p. 2604-2611, 2002/08
  • N141I mutant Presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression, M Mori,H Nakagami,R Morishita,N Mitsuda,K Yamamoto,S Yoshimura,N Ohkubo,N Sato,T Ogihara,Y Kaneda, LIFE SCIENCES, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 70, No. 21, p. 2567-2580, 2002/04
  • Tumor necrosis factor-alpha inhibits growth factor-mediated cell proliferation through SHP-1 activation in endothelial cells, H Nakagami,TX Cui,M Iwai,T Shiuchi,Y Takeda-Matsubara,L Wu,M Horiuchi, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 22, No. 2, p. 238-242, 2002/02
  • Estrogen activates phosphatases and antagonizes growth-promoting effect of angiotensin II, Y Takeda-Matsubara,H Nakagami,M Iwai,TX Cui,T Shiuchi,M Akishita,C Nahmias,M Ito,M Horiuchi, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, No. 1, p. 41-45, 2002/01
  • Effect of angiotensin II type 1 receptor blockade on cardiac remodeling in angiotensin II type 2 receptor null mice, L Wu,M Iwai,H Nakagami,R Chen,J Suzuki,M Akishita,M de Gasparo,M Horiuchi, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 22, No. 1, p. 49-54, 2002/01
  • Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model - Molecular mechanisms of delayed angiogenesis in diabetes, Y Taniyama,R Morishita,K Hiraoka,M Aoki,H Nakagami,K Yamasaki,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 19, p. 2344-2350, 2001/11
  • Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy, M Takemoto,K Node,H Nakagami,YL Liao,M Grimm,Y Takemoto,M Kitakaze,JK Liao, JOURNAL OF CLINICAL INVESTIGATION, AMER SOC CLINICAL INVESTIGATION INC, Vol. 108, No. 10, p. 1429-1437, 2001/11
  • Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury, L Wu,M Iwai,H Nakagami,Z Li,R Chen,J Suzuki,M Akishita,M de Gasparo,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 22, p. 2716-2721, 2001/11
  • Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element "decoy' of nuclear factor-kB binding site as a novel molecular strategy, S Yoshimura,R Morishita,K Hayashi,K Yamamoto,H Nakagami,Y Kaneda,N Sakai,T Ogihara, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 8, No. 21, p. 1635-1642, 2001/11
  • Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons, K Hayashi,R Morishita,H Nakagami,S Yoshimura,A Hara,K Matsumoto,T Nakamura,T Ogihara,Y Kaneda,N Sakai, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 8, No. 15, p. 1167-1173, 2001/08
  • Endothelial apoptosis induced by oxidative stress through activation of NF-kappa B - Antiapoptotic effect of antioxidant agents on endothelial cells, M Aoki,T Nata,R Morishita,H Matsushita,H Nakagami,K Yamamoto,K Yamazaki,M Nakabayashi,T Ogihara,Y Kaneda, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 38, No. 1, p. 48-55, 2001/07
  • Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells, H Nakagami,R Morishita,K Yamamoto,S Yoshimura,Y Taniyama,M Aoki,H Matsubara,S Kim,Y Kaneda,T Ogihara, DIABETES, AMER DIABETES ASSOC, Vol. 50, No. 6, p. 1472-1481, 2001/06
  • Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells, K Yamamoto,R Morishita,S Hayashi,H Matsushita,H Nakagami,A Moriguchi,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 37, No. 5, p. 1341-1348, 2001/05
  • Pivotal role of tyrosine phosphatase SHP-1 in AT2 receptor-mediated apoptosis in rat fetal vascular smooth muscle cell, TX Cui,H Nakagami,M Iwai,Y Takeda,T Shiuchi,L Daviet,C Nahmias,M Horiuchi, CARDIOVASCULAR RESEARCH, ELSEVIER SCIENCE BV, Vol. 49, No. 4, p. 863-871, 2001/03
  • Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease, Y Taniyama,R Morishita,M Aoki,H Nakagami,K Yamamoto,K Yamazaki,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 8, No. 3, p. 181-189, 2001/02
  • Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and Akt in endothelial cells, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,K Matsumoto,T Nakamura,Y Kaneda,M Horiuchi,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 37, No. 2, p. 581-586, 2001/02
  • Involvement of bradykinin and nitric oxide in leptin-mediated glucose uptake in skeletal muscle, T Shiuchi,H Nakagami,M Iwai,Y Takeda,TX Cui,R Chen,Y Minokoshi,M Horiuchi, ENDOCRINOLOGY, ENDOCRINE SOC, Vol. 142, No. 2, p. 608-612, 2001/02
  • ATRAP, novel AT1 receptor associated protein, enhances internalization of AT1 receptor and inhibits vascular smooth muscle cell growth, TX Cui,H Nakagami,M Iwai,Y Takeda,T Shiuchi,K Tamura,L Daviet,M Horiuchi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 279, No. 3, p. 938-941, 2000/12
  • Anti-apoptotic action of hepatocyte growth factor through mitogen-activated protein kinase on human aortic endothelial cells, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,S Kim,K Matsumoto,T Nakamura,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, No. 10, p. 1411-1420, 2000/10
  • Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model - Potential application of ribozyme strategy to treat cardiovascular disease, K Yamamoto,R Morishita,N Tomita,T Shimozato,H Nakagami,A Kikuchi,M Aoki,J Higaki,Y Kaneda,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 11, p. 1308-1314, 2000/09
  • Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters, Y Taniyama,R Morishita,H Nakagami,A Moriguchi,H Sakonjo,Shokei-Kim,K Matsumoto,T Nakamura,J Higaki,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 2, p. 246-+, 2000/07
  • Hypoxia-induced endothelial apoptosis through nuclear factor-kappa B (NF-kappa B)-mediated bcl-2 suppression - In vivo evidence of the importance of NF-kappa B in endothelial cell regulation, H Matsushita,R Morishita,T Nata,M Aoki,H Nakagami,Y Taniyama,K Yamamoto,J Higaki,K Yasufumi,T Ogihara, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 86, No. 9, p. 974-981, 2000/05
  • Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells, H Matsushita,R Morishita,M Aoki,N Tomita,Y Taniyama,H Nakagami,T Shimozato,J Higaki,Y Kaneda,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 101, No. 12, p. 1447-1452, 2000/03
  • Contribution of cardiovascular hypersensitivity to orthostatic hypertension and the extreme dipper phenomenon, A Moriguchi,H Nakagami,N Kotani,J Higaki,T Ogihara, HYPERTENSION RESEARCH, JAPANESE SOC HYPERTENSION CENT ACADEMIC SOC, PUBL OFFICE, Vol. 23, No. 2, p. 119-123, 2000/03
  • Gene therapy for myocardial infarction: A real medicine in the next millenium?, R Morishita,M Aoki,H Nakagami,Y Taniyama,K Yamamoto,H Matsushita,K Matsumoto,J Higaki,Y Kaneda,T Ogihara, HEART FAILURE, SPRINGER-VERLAG TOKYO, p. 219-226, 2000
  • Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21, S Hayashi,R Morishita,H Matsushita,H Nakagami,Y Taniyama,T Nakamura,M Aoki,K Yamamoto,J Higaki,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 35, No. 1, p. 237-243, 2000/01
  • Isolation and characterization of the E2F-like gene in plants, M Sekine,M Ito,K Uemukai,Y Maeda,H Nakagami,A Shinmyo, FEBS LETTERS, ELSEVIER SCIENCE BV, Vol. 460, No. 1, p. 117-122, 1999/10
  • Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms, H Nakagami,U Ikeda,Y Maeda,K Yamamoto,Y Hojo,K Kario,S Kuroki,K Shimada, JOURNAL OF THROMBOSIS AND THROMBOLYSIS, KLUWER ACADEMIC PUBL, Vol. 8, No. 3, p. 191-195, 1999/10
  • Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells - Potential role of p53 in regulation of vascular smooth muscle cell growth, M Aoki,R Morishita,H Matsushita,S Hayashi,H Nakagami,K Yamamoto,A Moriguchi,Y Kaneda,J Higaki,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 34, No. 2, p. 192-200, 1999/08
  • Relative localization of angiotensin-converting enzyme, chymase and angiotensin II in human coronary atherosclerotic lesions, OHISHI M,UEDA M,RAKUGI H,NARUKO T,KOJIMA A,OKAMURA A,HIGAKI J,OGIHARA T, Journal of Hypertension, Vol. 17, No. 4, p. 547-553, 1999
  • Recurrent arterial thrombotic disease on young onset and protein S deficiency, H Nakagami,K Kario,T Mitsuhashi,H Fujikawa,U Ikeda,K Shimada, BLOOD COAGULATION & FIBRINOLYSIS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 9, No. 7, p. 667-668, 1998/10
  • Mitral regurgitation reduces the risk of stroke in patients with nonrheumatic atrial fibrillation, H Nakagami,K Yamamoto,U Ikeda,T Mitsuhashi,T Goto,K Shimada, AMERICAN HEART JOURNAL, MOSBY-YEAR BOOK INC, Vol. 136, No. 3, p. 528-532, 1998/09
  • Oligonucleotide-based gene therapy for cardiovascular disease, R Morishita,H Nakagami,Y Taniyama,H Matsushita,K Yamamoto,N Tomita,A Moriguchi,K Matsumoto,J Higaki,T Ogihara, CLINICAL CHEMISTRY AND LABORATORY MEDICINE, WALTER DE GRUYTER & CO, Vol. 36, No. 8, p. 529-534, 1998/08
  • Angiotensin converting enzyme gene polymorphism in essential hypertension based on ambulatory blood pressure monitoring, Y Maeda,U Ikeda,H Ebata,Y Hojo,Y Seino,H Nakagami,K Shimada, AMERICAN JOURNAL OF HYPERTENSION, ELSEVIER SCIENCE INC, Vol. 10, No. 7, p. 786-789, 1997/07
  • Diurnal blood pressure rhythm in hypertensives with parental history of stroke, Y Maeda,U Ikeda,H Ebata,Y Hojo,H Nakagami,K Shimada, AMERICAN JOURNAL OF HYPERTENSION, ELSEVIER SCIENCE INC, Vol. 10, No. 5, p. 562-564, 1997/05
  • Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans, OHISHI M,UEDA M,RAKUGI H,NARUKO T,KOJIMA A,OKAMURA A,HIGAKI J,OGIHARA T, Journal of Hypertension, Vol. 15, No. 11, p. 1295-1302, 1997

Misc.

  • 炎症制御をターゲットにした脳梗塞急性期治療薬開発の現状と展望, 島村 宗尚,中神 啓徳,佐々木 勉,森下 竜一,望月 秀樹, 臨床神経学, Vol. 60, p. 253-259, 2020
  • Therapeutic Vaccines for Hypertension: a New Option for Clinical Practice, Hironori Nakagami,Ryuichi Morishita, Current Hypertension Reports, Current Medicine Group LLC 1, Vol. 20, No. 3, 2018/03/01
  • S100A9タンパク質を標的とした新規抗血栓ワクチンによる脳梗塞予防法の開発, 河野友裕,河野友裕,島村宗尚,島村宗尚,中神啓徳,佐々木勉,森下竜一,望月秀樹, 日本心血管内分泌代謝学会学術総会プログラム及び抄録集, (株)メディカルレビュー社, Vol. 21st, No. 2, p. 110-104, 2017/12
  • 肥満に伴う脂肪炎症におけるマクロファージのリソソーム開口放出制御因子Myoferlinの機能解明, 野里 陽一,鷹見 洋一,中神 啓徳,山本 浩一,華山 力成,楽木 宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 4, p. 1379-1379, 2017/12
  • HVJ-Eベクターを用いた遺伝子機能スクリーニング法による血管内皮由来の新規酸化ストレス調節因子の探索, 永澤 元規,鷹見 洋一,中神 啓徳,山本 浩一,金田 安史,楽木 宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 4, p. 1388-1388, 2017/12
  • 難治性皮膚潰瘍治療薬開発を目指した新規機能性ペプチドの実用化, 中神 啓徳,楽木 宏実, 日本老年医学会雑誌, (一社)日本老年医学会, Vol. 54, No. 4, p. 621-622, 2017/10
  • 肥満に伴う脂肪炎症におけるマクロファージのリソソーム開口放出制御因子Myoferlinの機能解明, 野里 陽一,鷹見 洋一,中神 啓徳,山本 浩一,華山 力成,楽木 宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 40回, p. 342-342, 2017/10
  • PCSK9ワクチンの開発, 野里 陽一,中神 啓徳,鷹見 洋一,山本 浩一,森下 竜一,楽木 宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 40回, p. 356-356, 2017/10
  • HVJ-Eベクターを用いた遺伝子機能スクリーニング法による血管内皮由来の新規酸化ストレス調節因子の探索, 永澤 元規,鷹見 洋一,中神 啓徳,山本 浩一,金田 安史,楽木 宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 40回, p. 428-428, 2017/10
  • 【高血圧の個別化医療】 高齢者高血圧の個別化医療 フレイルからワクチンまで, 勝谷 友宏,中神 啓徳,楽木 宏実,森下 竜一, 血圧, (株)先端医学社, Vol. 24, No. 9, p. 627-632, 2017/09
  • 【循環器疾患のprecision medicine】 血圧コントロールのprecision medicine, 中神 啓徳,楽木 宏実, 循環器内科, (有)科学評論社, Vol. 82, No. 1, p. 49-54, 2017/07
  • 新規の降圧治療法開発への期待 臨床試験に向けたアンジオテンシンIIワクチンの開発, 中神 啓徳,郡山 弘,楽木 宏実,森下 竜一, 日本高血圧学会臨床高血圧フォーラムプログラム・抄録集, (NPO)日本高血圧学会, Vol. 6回, p. 105-105, 2017/05
  • S100A9タンパク質を標的とした新規抗血栓ワクチンによる脳梗塞予防法の開発, 河野友裕,島村宗尚,島村宗尚,中神啓徳,郡山弘,佐々木勉,坂口学,楽木宏実,望月秀樹, 日本心血管脳卒中学会学術集会プログラム・抄録集, Vol. 4th, 2017/04/24
  • パーキンソン病原因分子αシヌクレインの加齢性血管内皮機能障害における新規病態生理機能, 鷹見 洋一,中神 啓徳,山本 浩一,森下 竜一,金田 安史,楽木 宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 92, No. 3, p. 893-893, 2017/01
  • 高血圧の先進治療 アンジオテンシンIIを標的とした高血圧・心不全ワクチンの開発, 中神 啓徳,郡山 宏,楽木 宏実,森下 竜一, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 39回, p. 265-265, 2016/09
  • 高血圧症に対するアンジオテンシンIIワクチンによる新規治療法の開発, 郡山 弘,中神 啓徳,勝谷 友宏,森下 竜一,楽木 宏実, 日本抗加齢医学会総会プログラム・抄録集, (一社)日本抗加齢医学会, Vol. 16回, p. 80-80, 2016/06
  • Therapeutic Application of an Angiotensin II Peptide Vaccine in a Middle Cerebral Artery Occlusion Model in Rats, Kouji Wakayama,Munehisa Shimamura,Jun-ichi Suzuki,Mitsuaki Isobe,Hironori Nakagami,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 47, 2016/02
  • Development of a Novel Anti-inflammatory and Anti-osteoplastic Peptide Based on De-loop and Ef-loop in Rankl for Treatment of Ischemic Stroke, Hitomi Kurinami,Munehisa Shimamura,Hironori Nakagami,Hideo Shimizu,Hiroshi Koriyama,Tomohiro Kawano,Hideki Mochizuki,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 47, 2016/02
  • A model of stroke and vascular injury in the brain, Munehisa Shimamura,Hironori Nakagami,Masataka Sata,Hitomi Kurinami,Kouji Wakayama,Hideki Mochizuki,Ryuichi Morishita, Mouse Models of Vascular Diseases, Springer Japan, p. 263-274, 2016/01/01
  • 血管病としての認知症~予防はどこまで可能か?~脳血管のアンチエイジングと認知症予防, 島村宗尚,島村宗尚,中神啓徳,里直行,望月秀樹,森下竜一, 分子脳血管病, Vol. 15, No. 1, 2016/01/01
  • 老化を科学する 糖尿病・脂質異常症と認知症, 島村宗尚,島村宗尚,里直行,里直行,中神啓徳,望月秀樹,森下竜一, 最新精神医学, Vol. 20, No. 6, 2015/11/25
  • Translational Research of Novel Angiogenic Peptide for Wound Healing Drug; From Discovery to Clinical Trial, Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 132, 2015/11
  • アンジオテンシンIIワクチンによる高血圧症の新規治療法の開発, 郡山 弘,中神 啓徳,勝谷 友宏,楽木 宏実,森下 竜一, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 38回, p. 362-362, 2015/10
  • 加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(Cylindromatosis)の病態生理学的役割の検討, 今泉 友希,鷹見 洋一,中神 啓徳,山本 浩一,楽木 宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 38回, p. 364-364, 2015/10
  • Impact of surface coated magnetite used in magnetic drug delivery system on immune response, Yoshihiro Oaku,Junya Tamada,Fumihito Mishima,Yoko Akiyama,Mariana Kiomy Osako,Hiroshi Koriyama,Hironori Nakagami,Shigehiro Nishijima, Journal of Applied Physics, Vol. 117, 2015/05/07
  • 各国の治療ガイドラインからみたRAS抑制薬の位置づけ 高齢者(認知症を含む)におけるRAS抑制薬の位置づけ, 島村宗尚,里直行,中神啓徳,森下竜一, Angiotensin Research, Vol. 12, No. 1, p. 43-49, 2015/01/01
  • Development of Therapeutic Vaccine for Angiotensin II, Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, JOURNAL OF CARDIAC FAILURE, CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, Vol. 20, No. 10, p. S151-S151, 2014/10
  • DEVELOPMENT OF DNA VACCINE FOR HIGH BLOOD PRESSURE - IMMUNOTHERPY FOR ANGIOTENSIN II., Hironori Nakagami,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, WILEY-BLACKWELL, Vol. 16, No. 7-8, p. 255-255, 2014/07
  • Research for Localized High-Efficient Gene Transfer by the Magnetic Force Control Using High Temperature Superconducting Bulk Magnet, Junya Tamada,Yoshihiro Oaku,Fumihito Mishima,Yoko Akiyama,Mariana KiomyOsako,Munehisa Shimamura,Hironori Nakagami,Shigehiro Nishijima, IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, Vol. 24, No. 3, 2014/06
  • 脳血管性認知症 2.脳のアンチエイジング, 島村宗尚,中神啓徳,里直行,森下竜一, Anti Aging Sci, Vol. 5, No. 2, p. 82-88, 2013/06/25
  • Rosuvastatin ameliorates obesity and proteinuria in zucker diabetic fatty rats, Hironori Nakagami,Takashi Shimosato,Munehisa Shimamura,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 13, p. 144-149, 2013/06/11
  • Study on magnetic gene transfer using HTS bulk magnet, Kota Nakagawa,Yoshihiro Ohaku,Junya Tamada,Fumihito Mishima,Yoko Akiyama,Mariana Kiomy Osako,Hironori Nakagami,Shigehiro Nishijima, Physica C: Superconductivity and its Applications, Vol. 494, p. 262-264, 2013/05/20
  • Chronic deposition of Aβ influences microcirculation in the chronic stage of cerebral Ischemia, Munehisa Shimamura,Naoyuki Sato,Hironori Nakagami,Mariana Kiomy Osako,Mariko Kyutoku,Kouji Wakayama,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 13, p. 77-80, 2013/04/30
  • Foreword: Gene therapy: Technologies and applications, Hironori Nakagami,Ryuichi Morishita, Gene Therapy: Technologies and Applications, Future Medicine Ltd., p. 3-4, 2013/03/01
  • Gene therapy: Technologies and applications, Ryuichi Morishita,Hironori Nakagami, Gene Therapy: Technologies and Applications, Future Medicine Ltd., p. 1-107, 2013/03/01
  • Plasmid DNA-based gene therapy in neurological disorders, Munehisa Shimamura,Hironori Nakagami,Hitomi Kurinami,Naoyuki Sato,Ryuichi Morishita, Gene Therapy: Technologies and Applications, p. 47-56, 2013/03/01
  • Prevention of Abdominal Aortic Aneurysms by Inhibition of Renin Activity in a Rabbit Model, Takashi Miyake,Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 126, No. 21, 2012/11
  • Potential Contribution of RANKL System in Adipose Tissue Inflammation and Insulin Resistance, Mariana K. Osako,Futoshi Nakagami,Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 126, No. 21, 2012/11
  • Ultrasound microbubbles and needleless jet injector for gene transfer of naked plasmid dna, Munehisa Shimamura,Hironori Nakagami,Naoyuki Sato,Yoshiaki Taniyama,Yasuo Kunigiza,Ryuichi Morishita, Plasmids: Genetics, Applications and Health, p. 137-147, 2012/08/01
  • Pitavastatin improves endothelial function and glucose metabolism in ovariectomized mice, Hironori Nakagami,Mariana Kiomy Osako,Natsuki Yasumasa,Munehisa Shimamura,Mariko Kyutoku,Futoshi Nakagami,Hiroshi Koriyama,Hideki Tomioka,Tomohiro Katsuya,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 12, p. 29-33, 2012/01/01
  • Lipoprotein(a) is a therapeutic target for cardiovascular disease, Mariko Kyutoku,Hironori Nakagami,Futoshi Nakagami,Hiroshi Koriyama,Mariana Kiomy Osako,Munehisa Shimamura,Takashi Miyake,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 12, p. 118-121, 2012/01/01
  • Screening of antihypertensive drugs for osteoclastic acid secretion and bone resorption by acridine orange, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Osako Kiomy Mariana,Mariko Kyutoku,Hiroshi Koriyama,Futoshi Nakagami,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 12, p. 161-167, 2012/01/01
  • Impact of Angiotensin II DNA Vaccine Treatment on Blood Pressure Reduction and Its Maintenance in Spontaneously Hypertensive Rats, Hiroshi Koriyama,Hironori Nakagami,Futoshi Nakagami,Tomohiro Katsuya,Ryuichi Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 58, No. 5, p. E160-E160, 2011/11
  • Cross-Talk of RANKL Signaling with Renin-Angiotensin II System in Vascular Calcification and Remodeling, Mariana K. Osako,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 124, No. 21, 2011/11
  • Prevention of Neointimal Hyperplasia After Angioplasty Using NF-kappaB Decoy Oligodeoxynucleotides-Coated Balloon Catheter in Rabbit Restenosis Model, Takashi Miyake,Munehisa Shimamura,Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 124, No. 21, 2011/11
  • Key Role Of Periostin In Cerebral Ischemia, Munehisa Shimamura,Yoshiaki Taniyama,Hironori Nakagami,Naoyuki Sato,Nobutaka Koibuchi,Mohammad Allahtavakoli,Kouji Wakayama,Takashi Miyake,Hideo Shimizu,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 42, No. 3, p. E67-E67, 2011/03
  • 糖尿病とアルツハイマー病の相互的病態修飾機序の解明, 武田朱公,里直行,内尾(山田)こずえ,湯久浩,守口篤,楽木宏実,中神啓徳,森下竜一, 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, Vol. 21st-41st, 2011
  • ENDOTHELIAL FHL-2 SUPPRESSES VEGF-INDUCED PI3K/AKT PATHWAY THROUGH INTERACTION WITH SPHINGOSINE KINASE-1, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Hiroshi Koriyama,Masaki Mori,Katsuto Tamai,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1026-1026, 2010/12
  • ZYXIN MEDIATES ACTIN FIBER REORGANIZATION IN EPITHELIAL-MESENCHYMAL TRANSITION AND CONTRIBUTES TO ENDOCARDIAL MORPHOGENESIS, Masaki Mori,Hironori Nakagami,Nobutaka Koibuchi,Koichi Miura,Yoichi Takami,Hiroshi Koriyama,Hiroki Hayashi,Hisataka Sabe,Naoki Mochizuki,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1050-1050, 2010/12
  • MODIFICATION OF NOVEL ANGIOGENIC PEPTIDE, AG-30, TOWARD CLINICAL APPLICATION, Hironori Nakagami,Tomoyuki Nishikawa,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1022-1022, 2010/12
  • ANALYSIS ON SIGNAL PATHWAY OF AN ANTIMICROBIAL AND ANIGOGENIC PEPTIDE, AG-30, STIMULATED ENDOTHELIAL CELLS, Tomoyuki Nishikawa,Hironori Nakagami,Ryuichi Morishita,Akito Maeda,Katsuto Tamai,Yasu-fumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1027-1027, 2010/12
  • GENOME-WIDE ASSOCIATION STUDY IN JAPANESE POPULATION IDENTIFIES SUSCEPTIBLE LOCI FOR PERIPHERAL ARTERIAL DISEASE., Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Ken Sugimoto,Hiroshi Akasaka,Shigeyuki Saitoh,Shiro Maeda,Yusuke Nakamura,Yasufumi Kaneda,Hiromi Rakugi,Ryuichi Morishita,Kazuaki Shimamoto,Toshio Ogihara, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1046-1046, 2010/12
  • A NOVEL STRATEGY OF THE GENE THERAPY FOR PAD USING SMALL RNA INTERFERENCE OF COLD SHOCK DOMAIN PROTEIN A, Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Nobuyoshi Azuma,Tadahiro Sasajima,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1036-1036, 2010/12
  • "Estrogen Prevents Aortic Calcification by inducing MGP Expression and Inhibiting BMP Expression in an Estrogen Receptor alpha Dependent Way, Mariana K. Osako,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 122, No. 21, 2010/11
  • 細胞運動・ECM・細胞接着 Zyxinは上皮間葉転換においてアクチン線維再編成に関与し心内膜床の形態形成に寄与する(Cell motility, ECM and cell adhesion Zyxin Mediates Actin Fiber Reorganization in Epithelial-Mesenchymal Transition and Contributes to Endocardial Morphogenesis), 森 雅樹,中神 啓徳,鯉渕 信孝,三浦 浩一,佐邊 壽孝,望月 直樹,金田 安史, 日本細胞生物学会大会講演要旨集, (一社)日本細胞生物学会, Vol. 62回, p. 120-120, 2010/05
  • RANKL System contributes the process of vascular calcification as well as osteoporosis, Mariana Osako,Hironori Nakagami,Ryuichi Morishita, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOC, Vol. 57, p. S339-S339, 2010/03
  • Combination of thiazide diuretics and angiotensin receptor blockers attenuates osteoporosis in hypertensive rats, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Mariana Kiomy Osako,Munehisa Shimamura,Takeshi Miyake,Futoshi Nakagami,Hiroshi Koriyama,Hiromi Rakugi,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 10, p. 115-122, 2010/01/01
  • MICRORNA TRANSFERRED TO HUMAN ADIPOSE TISSUE-DERIVED STEM CELLS BY LENTIVIRUS VECTOR ENHANCED ADIPOGENESIS THROUGH DOWNREGULATION OF HOMEOBOX C8, Masaki Mori,Hironori Nakagami,Hiroki Hayashi,Hiroshi Koriyama,Yoichi Takami,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1167-1167, 2009/12
  • IDENTIFICATION OF ENDOGENOUS ANGIOGENIC REPRESSOR, FHL-2, VIA DIRECT INTERACTION WITH SPHINGOSINE KINASE-1 IN ENDOTHELIAL CELLS, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Hiroshi Koriyama,Masaki Mori,Katsuto Tamai,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1152-1153, 2009/12
  • COLD SHOCK DOMAIN PROTEIN A, NOVEL REPRESSOR OF TUMOR-ANGIOGENESIS AND - LYMPHANGIOGENESIS FOR CANCER GENE THERAPY, Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Nobuyoshi Azuma,Tadahiro Sasajima,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1152-1152, 2009/12
  • ANALYSIS OF DE NOVO ENGINEERED VARIANTS OF AG-30 FOR THE TREATMENT OF ISCHEMIC DISEASES AND INFECTIOUS DISEASES, Tomoyuki Nishikawa,Hironori Nakagami,Ryuichi Morishita,Akito Maeda,Katsuto Tamai,Kazunori Tomono,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1166-1167, 2009/12
  • Identification of Novel Therapeutic Targets for Metabolic Syndrome by Functional Gene Screening, H. Nakagami,T. Katsuya,Y. Takami,H. Rakugi,R. Morishita,Y. Kaneda, CLINICAL AND EXPERIMENTAL HYPERTENSION, TAYLOR & FRANCIS INC, Vol. 31, No. 6, p. 486-486, 2009
  • Modulation of Atherosclerotic Plaque Characteristics by Minocycline: An Evaluation by Molecular Imaging of Matrix Metalloprotainase (MMP) Expression, Satoru Ohshima,Shinichiro Fujimoto,Hironori Nakagami,Nezarn Haider,Jun Zhou,Mariana K. Osako,Ai Fujimoto,Jie Zhu,Navneet Narula,Toyoaki Murohara,Artiom Petrov,Ryuichiro Morishita,Jagat Narula, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 118, No. 18, p. S645-S645, 2008/10
  • OSBPL10 is Identified as a Novel Susceptible Gene for Peripheral Arterial Disease by Genome-Wide Association Study in Japan, Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Ken Sugimoto,Hidetoshi Yamashita,Yoichi Takami,Hiroshi Akasaka,Shigeyuki Saitoh,Shiro Maeda,Yusuke Nakamura,Yasufumi Kaneda,Hiromi Rakugi,Kazuaki Shimamoto,Ryuichi Morishita,Toshio Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 118, No. 18, p. S1144-S1144, 2008/10
  • Genom-wide association study identifies susceptible loci for atherosclesosis obliterance, H. Koriyama,H. Nakagami,T. Katsuya,K. Sugimoto,H. Yamashita,Y. Takami,M. Mori,H. Hayashi,H. Rakugi,R. Morishita,S. Maeda,Y. Nakamura,Y. Kaneda,T. Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 26, p. S139-S139, 2008/06
  • Pivotal roles of CYLD (cylindromatosis) as a deubiquitinating enzyme in vascular remodeling, Y. Takami,H. Nakagami,R. Morishita,T. Katsuya,H. Rakugi,Y. Kaneda,T. Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 26, p. S310-S310, 2008/06
  • Therapeutic potential of ribbon type oligodeoxynucleotide decoy NF-kappa B in cardiovascular diseases, Mariana K. Osako,Naruya Tomita,Hironori Nakagami,Ryuichi Morishita, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 44, No. 2, p. 443-443, 2008/02
  • Anti-inflammatory and anti-proliferative action of cylindromatosis (CYLD) in atherosclerosis as a deubiquitinating enzyme, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 116, No. 16, p. 108-108, 2007/10
  • Potential contribution of action of renin angiotensin system to bone metabolism, Hironori Nakagami,Mariana Kiomy Osaka,Hideo Shimizu,Rie Hanayama,Ryuichi Morishita, Current Hypertension Reviews, Vol. 3, No. 2, p. 129-132, 2007/05
  • Favorable effects of statins beyond lipid lowering, Hironori Nakagami,Yasufumi Kaneda,Tosbio Ogihara,Ryuichi Morishita, FUTURE LIPIDOLOGY, FUTURE MEDICINE LTD, Vol. 1, No. 1, p. 75-80, 2007/02
  • Development of high throughput functional screening of cardiovascular therapeutic genes using the HVJ-E vector: Analysis of a novel angiogenic peptide, AG-30, Tomoyuki Nishikawa,Hironori Nakagami,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 8, No. 12, p. 1443-1444, 2006/12
  • Novel high through-put functinal screening by HVJ-E - targetting of antivascular remodeling factors in hypertension, Yoichi Takami,Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 237-237, 2006/12
  • HMG-CoA reductase inhibitor (fluvastatin) ameliorates the activation of osteoclast as an antioxidant, Rie Hanayama,Hironori Nakagami,Hideo Shimuzu,Natsuki Yasumasa,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 398-398, 2006/12
  • Angiotensin converting enzyme inhibitors (imidapril) ameliorates the osteoporosis in rat ovariectomized model, Natsuki Yasumasa,Hironori Nakagami,Hideo Shimizu,Rie Hanayama,Toshio Ogihara,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 257-257, 2006/12
  • Association of a gene polymorphism of novel Z-disc protein, myospryn, and left ventricular diastolic dysfunction, Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Yoichi Takami,Hiroshi Akasaka,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 381-381, 2006/12
  • Hepatocyte growth factor ameliorates secondary lymphedema via promotion of lymphangiogenesis., Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Yoichi Takami,Katsuto Tamai,Yasuhumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 408-408, 2006/12
  • Angiotensin II receptor blockade (RNH-6270) ameliorates osteoporosis, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Rie Hanayama,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 100-100, 2006/12
  • Ubiquitincarboxyl-terminalesterase L1, causative gene of Parkinson's disease, has anti-inflammatory action in vascular cells, Yoichi Takami,Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 54-55, 2006/12
  • gamma-secretase is new therapeutic target for anti-angiogenic therapy, Hiroki Hayashi,Hironori Nakagami,Yukihiro Saito,Yoichi Talkami,Tomoyuki Nishikawa,Naoyuki Sato,Ryuichi Morishita,Yasufumi Kaneda, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 4, p. E94-E94, 2006/10
  • Ubiquitin carboxyl-terminal esterase L1, causative gene of Parkinson's disease, modulates anti-inflammatory-mediated vascular remodeling, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 114, No. 18, p. 257-257, 2006/10
  • Gene polymorphism of novel Z-disc protein, myospryn, is associated with left ventricular hypertrophy and diastolic dysfunction, Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Yasushi Kikuchi,Hiroshi Akasaka,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 4, p. E78-E78, 2006/10
  • Development of High Throughput Functional Screening of Cardiovascular Therapeutic Genes Using the HVJ-E Vector, Tomoyuki Nishikawa,Hironori Nakagami,Atsuhi Matsuki,Yukihiro Saito,Ryuichi Morishita,Katsuto Tamai,Yasufumi Kaneda, MOLECULAR THERAPY, NATURE PUBLISHING GROUP, Vol. 13, p. S336-S336, 2006/05
  • NFkB Decoy Oligodeoxynucleotides Inhibit Osteoclast Differentiation and Activation In Vitro and Improve Osteoporosis of Ovariectomized and Vitamin C Difficient Rat Models, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Rie Hanayama,Toshio Ogihara,Ryuichi Morishita, MOLECULAR THERAPY, NATURE PUBLISHING GROUP, Vol. 13, p. S275-S275, 2006/05
  • Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells, H Nakagami,K Maeda,Y Kaneda,T Ogihara,R Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 46, No. 4, p. 867-867, 2005/10
  • Identification of novel angiogenic peptide, Ag-30, H Nakagami,T Nishikawa,R Morishita,Y Kaneda, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 112, No. 17, p. U256-U256, 2005/10
  • Development of HVJ-E high throughput gene function screening system: Screening of endothelial cell growth factors, T Nishikawa,H Nakagami,CY Yo,Y Kaneda, MOLECULAR THERAPY, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 9, p. S113-S114, 2004/05
  • Statins attenuate cardiac hypertrophy through inhibition of NOX2-containing NADPH oxidase, H Nakagami,R Morishita,Y Kaneda,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 22, p. S115-S115, 2004/02
  • Statins attenuate angiotensin II-Induced cardiac hypertrophy through inhibition of gp91PHOX-Containing NADPH oxidase, H Nakagami,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 108, No. 17, p. 45-45, 2003/10
  • Inhibition of angiotensin II-induced cardiac hypertrophy by antioxidants, M Takemoto,H Nakagami,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 107, No. 19, p. E183-E183, 2003/05
  • Ventricular septal defects, cardiomyopathy, and vascular smooth muscle dysfunction in mice lacking the transcription factor CHF1/Hey2, MT Chin,Y Sakata,Y Kiriyama,CN Kamei,H Nakagami,ZP Chen,DI Simon,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 19, p. I-I, 2002/11
  • Ventricular septal defects, cardiomyopathy and vascular smooth muscle dysfunction in mice lacking the transcription factor CHF1/Hey2, MT Chen,Y Sakata,Y Kiriyama,CN Kamei,H Nakagami,ZP Chen,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 19, p. 229-229, 2002/11
  • Role of the expression of distinct AT(1) receptor and AT(2) receptor in pregnancy-induced hypertension, Y Takeda-Matsubara,H Nakagami,M Iwai,TX Cui,T Shiuchi,L Wu,LJ Ming,M Ito,M Horiuchi, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 20, p. S36-S36, 2002/06
  • Possible roles of interaction of AT1 and AT2 receptors in preeclampsia: Study using AT1 receptor null mice and AT2 receptor null mice, Y Takeda-Matsubara,H Nakagami,M Iwai,TX Cui,T Shiuchi,L Wu,LJ Ming,M Ito,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 17, p. 277-277, 2001/10
  • Effects of ACE inhibitor, imidapril, on vascular remodeling after cuff placement in AT1A receptor null mouse: Involvement of nitric oxide in the action of ACE inhibitor, R Chen,M Iwai,L Wu,H Nakagami,Z Li,M Hamai,J Suzuki,Y Takeda-Matsubara,T Shiuchi,T Sugaya,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 17, p. 90-91, 2001/10
  • Role of angiotensin II receptor subtypes in the regulation of apoptosis in vascular remodeling in vivo., J Suzuki,M Iwai,W Lan,H Nakagami,T Sugaya,T Seiyaku,M Hamada,K Hiwada,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 17, p. 296-296, 2001/10
  • At1 receptor blocker improves pressure-overload induced cardiac remodeling via AT1 receptor inhibition and AT2 receptor stimulation: Study using AT2 receptor null mice, L Wu,M Iwai,M Akishita,H Nakagami,M De Gasparo,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 72-72, 2000/10
  • Improvement of inflammatory vascular injury by AT(1) receptor blocker depends on AT(1) receptor blockade and AT(2) receptor stimulation: Evaluation of the role of AT(2) receptor using AT(2) receptor null mice, L Wu,M Iwai,H Nakagami,R Chen,M Akishita,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 275-275, 2000/10
  • Estrogen activates tyrosine and serine/threonine phosphatases and antagonizes the growth promoting effect of angiotensin II AT1 receptor in vascular smooth muscle cells, Y Takeda,H Nakagami,M Iwai,M Akishita,TX Cui,M Ito,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 180-180, 2000/10
  • Novel therapeutic strategy for restenosis using ribozyme oligonucleotides against transforming growth factor-beta, K Yamamoto,R Morishita,N Tomita,H Nakagami,M Aoki,J Higaki,Y Kaneda,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 36, No. 4, p. 728-729, 2000/10
  • Signaling of AT2 receptor-mediated cell death in fetal vascular smooth muscle cells pivotal role of SHP-1 via inhibition of ERK and AKT, TX Cui,H Nakagami,M Iwai,C Nahmias,T Shiuchi,K Toku,Y Kondo,Y Takeda,L Daviet,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 52-52, 2000/10
  • Hgf/NK4 as potential antagonist for diabetic retinopathy: Inhibition of VEGF-induced angiogenesis by HGF/NK4., M Nakabayashi,H Nakagami,K Yamamoto,M Aoki,Y Kaneda,R Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 249-249, 2000/10
  • Hypoxia induced renal epithelial cell death through caspase-dependent pathway: Role of bcl-2, bcl-xL and bax in tubular injury, K Yamamoto,R Morishita,N Tomita,Y Taniyama,M Aoki,H Nakagami, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 517-517, 2000/10
  • Mitogenic and anti-apoptotic actions of hepatocyte growth factor through ERK, STAT3 and AKT in human aortic endothelial cells, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,Y Kaneda,M Horiuchi,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 36, No. 4, p. 708-708, 2000/10
  • Molecular mechanism of cell death pathway induced by high D-glucose in human endothelial cell, H Nakagami,R Morishita,K Yamamoto,M Horiuchi,Y Kaneda,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S199-S199, 2000
  • Pre-clinical studies of therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hind limb ischemia models, Y Taniyama,R Morishita,M Aoki,H Nakagami,K Yamamoto,K Yamasaki,Y Kaneda,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S182-S182, 2000
  • Induction of transcription factor ETS-1 in endothelial cells by hepatocyte growth factor (HGF), N Tomita,R Morishita,H Nakagami,Y Taniyama,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S181-S181, 2000
  • Hypoxia induced renal epithelial cell death through caspase-dependent pathway: Role of bcl-2, Bcl-x/L and Bax in tubular injury, K Yamamoto,R Morishita,N Tomita,H Nakagami,Y Taniyama,M Aoki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S99-S99, 2000
  • Phosphrylation of p38 MAP kinase in the gown-stream of Bax-caspase 3 pathway leads to apoptosis induced by high D-glucose in human endothelial cells: Cross-talk between p38MAPK and caspase proteases, H Nakagami,K Yamamoto,S Yoshimura,R Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 64-64, 1999/11
  • Hypoxia induced apoptosis through oxidative stress-NF kappa B-mediated Bax translocation in human aortic endothelial cells, T Nata,H Matsushita,H Nakagami,M Aoki, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 267-267, 1999/11
  • Endothelial apoptosis induced by high D-glucose was prevented by hepatocyte growth factor through up-regulation of Bcl-2 and inhibition of translocation of Bax, H Nakagami,K Yamamoto,S Yoshimura, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 267-267, 1999/11
  • Reduced risk for thromboembolism in atrial fibrillation and mitral regurgitation - Reply, K Yamamoto,H Nakagami,U Ikeda,K Shimada, AMERICAN HEART JOURNAL, MOSBY-YEAR BOOK INC, Vol. 138, No. 5, p. 998-999, 1999/11
  • Cardio-protective effects of hepatocyte growth factor (HGF) gene transfer into the myocardium of cardiomyopathic hamster (Bio 14.6): novel gene therapy strategy for cardiomyopathy, Y Taniyama,M Aoki,T Nata,H Nakagami,R Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 47-48, 1999/11
  • Accumulation of cyclic AMP inhibited growth of human aortic vascular smooth muscle cells, accompanied by induction of anti-oncogenes, p53 and p21, and an endothelium-specific growth factor, hepatocyte growth factor, S Hayashi,H Nakagami,R Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 34, No. 2, p. 343-343, 1999/08
  • Importance of transcriptional factor NFkB, in hypoxia-induced death and apoptosis in human aortic endothelial cells., H Matsushita,R Morishita,H Nakagami,Y Taniyama,J Higaki, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 98, No. 17, p. 38-38, 1998/10
  • Anti-fibrotic action of hepatocyte growth factor by up-regulation of matrix metalloprotease-1 and urokinase-type plasminogen activator (uPA) in human fibroblasts and vascular smooth muscle cells (VSMC)., Y Taniyama,K Matsumoto,H Nakagami, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 98, No. 17, p. 810-810, 1998/10
  • Beneficial angiogenesis induced by over-expresssion of human hepatocyte growth factor (HGF) in non-infarcted and infarcted myocardium: Potential gene therapy for myocardial infarction, M Aoki,R Morishita,H Matsushita,S Hayashi,Y Taniyama,H Nakagami,T Nakamura,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 98, No. 17, p. 321-321, 1998/10
  • Molecular mechanisms of high D-glucose induced apoptosis in human endothelial-cells (EC): Contribution of mitogen-activated protein kinase (MAPK) cascade and apoptosis related genes, bax and bcl-2, H Nakagami,R Morishita,H Matsushita,S Hayashi,N Tomita,Y Taniyama,K Yamamoto,A Moriguchi,J Higaki,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 32, No. 3, p. 620-620, 1998/09
  • Role of hepatocyte growth factor (HGF) on endothelial cell damage in diabetes mellitus (DM) through its anti-apoptotic action, H Nakagami,R Morishita,H Matsushita,S Hayashi,K Moriguchi,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 16, p. S58-S58, 1998/06
  • Prevention of hypoxia-induced endothelial cell death by hepatocyte growth factor (HGF) through anti-apoptotic action, S Hayashi,R Morishita,H Matsushita,H Nakagami,A Moriguchi,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 16, p. S66-S66, 1998/06
  • Importance of transcriptional factor NF kappa B in hypoxia-induced death and apoptosis of human aortic endothelial cells, H Matsushita,R Morishita,S Hayashi,Y Taniyama,N Tomita,H Nakagami,K Yamamoto,A Moriguchi,Y Kaneda,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 16, p. S64-S64, 1998/06

Industrial Property Rights

  • 炎症性皮膚疾患の予防又は治療剤, 島村 宗尚,中神 啓徳,池田 裕香,森下 竜一,郡山 弘, 特許第6710416号, WO2018-084311, JP2017040115, 出願日:2017/11/07, 登録日:2020/05/29
  • ワクチン組成物, 佐藤 靖史,中神 啓徳,冨岡 英樹, WO2019-045025, JP2018032276, 出願日:2018/08/30
  • S100A9を標的とする免疫原性組成物, 島村 宗尚,河野 友裕,中神 啓徳,森下 竜一,望月 秀樹,天満 昭子,江原 貴子, WO2018-155457, JP2018006082, 出願日:2018/02/20
  • 疾患の要因となる生体内タンパク質を標的とするコンジュゲートワクチン, 中神 啓徳,森下 竜一,天満 昭子, WO2017-164409, JP2017012187, 出願日:2017/03/24
  • ペプチドワクチン及び当該ペプチドに対する特異抗体を有効成分とする医薬, 横田 陽匡,中神 啓徳,吉田 晃敏, 特願2017-051014, 出願日:2017/03/16