Researcher Directory - Osaka University

Nakagami Hironori

中神　啓徳

Graduate School of Medicine, Endowed Chair Professor

Research Areas

Life sciences, Internal medicine - General

Papers

Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine, Hirotaka Fukami,Jun Morinaga,Hironori Nakagami,Hiroki Hayashi,Yusuke Okadome,Eiji Matsunaga,Tsuyoshi Kadomatsu,Haruki Horiguchi,Michio Sato,Taichi Sugizaki,Keishi Miyata,Daisuke Torigoe,Masashi Mukoyama,Ryuichi Morishita,Yuichi Oike, npj Vaccines, Springer Science and Business Media LLC, Vol. 8, No. 1, 2023/11/01
Intradermal administration of DNA vaccine targeting Omicron SARS-CoV-2 via pyro-drive jet injector provides the prolonged neutralizing antibody production via germinal center reaction, Hiroki Hayashi,Jiao Sun,Yuka Yanagida,Takako Otera,Jiayu A. Tai,Tomoyuki Nishikawa,Kunihiko Yamashita,Naoki Sakaguchi,Shota Yoshida,Satoshi Baba,Chin Yang Chang,Munehisa Shimamura,Sachiko Okamoto,Yasunori Amaishi,Hideto Chono,Junichi Mineno,Hiromi Rakugi,Ryuichi Morishita,Hironori Nakagami, Scientific Reports, Springer Science and Business Media LLC, Vol. 13, No. 1, 2023/08/10
Impact of insufficient recovery of cerebral blood flow due to partial reperfusion on the pathophysiology of ischemic stroke in mice, Munehisa Shimamura,Chin yang Chang,Hiroki Hayashi,Satoshi Baba,Shota Yoshida,Hironori Nakagami, Neuroscience Letters, Elsevier BV, Vol. 810, p. 137370-137370, 2023/07
R-spondin 3/LGR4 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 4) Axis Is a Novel Inflammatory and Neurite Outgrowth Signaling System in the Ischemic Brain in Mice., Munehisa Shimamura,Hiroki Hayashi,Nan Ju,Shota Yoshida,Satoshi Baba,Tsutomu Sasaki,Hideki Mochizuki,Ryuichi Morishita,Hironori Nakagami, Stroke, Vol. 54, No. 6, p. 1606-1615, 2023/06
Renal dysfunction, malignant neoplasms, atherosclerotic cardiovascular diseases, and sarcopenia as key outcomes observed in a three-year follow-up study using the Werner Syndrome Registry., Yukari Maeda,Masaya Koshizaka,Mayumi Shoji,Hiyori Kaneko,Hisaya Kato,Yoshiro Maezawa,Junji Kawashima,Kayo Yoshinaga,Mai Ishikawa,Akiko Sekiguchi,Sei-Ichiro Motegi,Hironori Nakagami,Yoshihiko Yamada,Shinji Tsukamoto,Akira Taniguchi,Ken Sugimoto,Yoichi Takami,Yukiko Shoda,Kunihiko Hashimoto,Toru Yoshimura,Asako Kogure,Daisuke Suzuki,Naoki Okubo,Takashi Yoshida,Kazuhisa Watanabe,Masafumi Kuzuya,Minoru Takemoto,Junko Oshima,Koutaro Yokote, Aging, Vol. 15, No. 9, p. 3273-3294, 2023/05/01
Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats, Hiroki Hayashi,Jiao Sun,Yuka Yanagida,Shota Yoshida,Satoshi Baba,Akiko Tenma,Masayoshi Toyoura,Sotaro Kawabata,Takako Ehara,Ryoko Asaki,Makoto Sakaguchi,Hideki Tomioka,Munehisa Shimamura,Ryuichi Morishita,Hiromi Rakugi,Tetsuya Tomita,Hironori Nakagami, RMD Open, BMJ, Vol. 9, No. 1, p. e002851-e002851, 2023/02
High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer’s Disease Via a Specific Tau Phosphorylation Pattern, Y. Ito,S. Takeda,T. Nakajima,A. Oyama,H. Takeshita,K. Miki,Y. Takami,Y. Takeya,M. Shimamura,H. Rakugi,R. Morishita, The Journal Of Prevention of Alzheimer's Disease, SERDI, 2023
Effects of nicotinamide mononucleotide on older patients with diabetes and impaired physical performance: A prospective, placebo-controlled, double-blind study., Hiroshi Akasaka,Hironori Nakagami,Ken Sugimoto,Yukiko Yasunobe,Tomohiro Minami,Taku Fujimoto,Koichi Yamamoto,Chikako Hara,Akihiko Shiraki,Kohji Nishida,Kento Asano,Masanobu Kanou,Kei Yamana,Shin-Ichiro Imai,Hiromi Rakugi, Geriatrics & Gerontology International, Vol. 23, No. 1, p. 38-43, 2023/01
Modified DNA vaccine confers improved humoral immune response and effective virus protection against SARS-CoV-2 delta variant, Hiroki Hayashi,Jiao Sun,Yuka Yanagida,Takako Otera,Miwa Sasai,Chin Yang Chang,Jiayu A. Tai,Tomoyuki Nishikawa,Kunihiko Yamashita,Naoki Sakaguchi,Shota Yoshida,Satoshi Baba,Munehisa Shimamura,Sachiko Okamoto,Yasunori Amaishi,Hideto Chono,Junichi Mineno,Hiromi Rakugi,Ryuichi Morishita,Masahiro Yamamoto,Hironori Nakagami, Scientific Reports, Springer Science and Business Media LLC, Vol. 12, No. 1, 2022/12/03
Prevention of bleomycin-induced pulmonary fibrosis by a RANKL peptide in mice, Nan Ju,Hiroki Hayashi,Munehisa Shimamura,Satoshi Baba,Shota Yoshida,Ryuichi Morishita,Hiromi Rakugi,Hironori Nakagami, Scientific Reports, Springer Science and Business Media LLC, Vol. 12, No. 1, p. 12474-12474, 2022/12
Morning surge in sympathetic nervous activity in the indoor environment during the cold winter season., Hironori Nakagami,Hitoshi Akiyama,Hiroki Otsuka,Sho Adnas Takahashi,Katsutoshi Sawada,Nobutoshi Kobayashi,Atsushi Iwamae,Hidekazu Yamada, Hypertension research : official journal of the Japanese Society of Hypertension, 2022/10/13
New wave of digital hypertension management for clinical applications., Hironori Nakagami, Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 45, No. 10, p. 1549-1551, 2022/10
Novel pathophysiological roles of α‐synuclein in age‐related vascular endothelial dysfunction, Yoichi Takami,Cheng Wang,Hironori Nakagami,Koichi Yamamoto,Yoichi Nozato,Yuki Imaizumi,Motonori Nagasawa,Hikari Takeshita,Tsuneo Nakajima,Shuko Takeda,Yasushi Takeya,Yasufumi Kaneda,Hiromi Rakugi, The FASEB Journal, Wiley, Vol. 36, No. 10, 2022/10
Preclinical study of a DNA vaccine targeting SARS-CoV-2, Hiroki Hayashi,Jiao Sun,Yuka Yanagida,Takako Otera,Ritsuko Kubota-Koketsu,Tatsuo Shioda,Chikako Ono,Yoshiharu Matsuura,Hisashi Arase,Shota Yoshida,Ryo Nakamaru,Nan Ju,Ryoko Ide,Akiko Tenma,Sotaro Kawabata,Takako Ehara,Makoto Sakaguchi,Hideki Tomioka,Munehisa Shimamura,Sachiko Okamoto,Yasunori Amaishi,Hideto Chono,Junichi Mineno,Takao Komatsuno,Yoshimi Saito,Hiromi Rakugi,Ryuichi Morishita,Hironori Nakagami, Current Research in Translational Medicine, Vol. 70, No. 4, p. 103348-103348, 2022/09
Phase I Study to Assess the Safety and Immunogenicity of an Intradermal COVID-19 DNA Vaccine Administered Using a Pyro-Drive Jet Injector in Healthy Adults., Hironori Nakagami,Hiroki Hayashi,Jiao Sun,Yuka Yanagida,Takako Otera,Futoshi Nakagami,Shigeto Hamaguchi,Hisao Yoshida,Hideo Okuno,Shota Yoshida,Ryo Nakamaru,Serina Yokoyama,Taku Fujimoto,Kazuhiro Hongyo,Yukihiro Akeda,Ryuichi Morishita,Kazunori Tomono,Hiromi Rakugi, Vaccines, Vol. 10, No. 9, 2022/08/30
Immune response induced in rodents by anti-CoVid19 plasmid DNA vaccine via pyro-drive jet injector inoculation., Tomoyuki Nishikawa,Chin Yang Chang,Jiayu A Tai,Hiroki Hayashi,Jiao Sun,Shiho Torii,Chikako Ono,Yoshiharu Matsuura,Ryoko Ide,Junichi Mineno,Miwa Sasai,Masahiro Yamamoto,Hironori Nakagami,Kunihiko Yamashita, Immunological medicine, Vol. 45, No. 4, p. 1-14, 2022/08/24
脳梗塞急性期治療のパラダイムシフト炎症制御をターゲットにした急性期脳梗塞の創薬研究, 島村宗尚,中神啓徳,佐々木勉,望月秀樹, 神経治療学, (一社)日本神経治療学会, Vol. 39, No. 4, p. 517-521, 2022/07
Blood pressure fluctuations and the indoor environment in a highly insulated and airtight model house during the cold winter season., Hironori Nakagami,Hiroshi Akiyama,Hiroki Otsuka,Atsushi Iwamae,Hidekazu Yamada, Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 45, No. 7, p. 1217-1219, 2022/07
Author Correction: A novel soluble epoxide hydrolase vaccine protects murine cardiac muscle against myocardial infarction., Takahiro Kitsuka,Aya Shiraki,Jun-Ichi Oyama,Hironori Nakagami,Atsushi Tanaka,Koichi Node, Scientific reports, Vol. 12, No. 1, p. 7737-7737, 2022/05/11
A novel soluble epoxide hydrolase vaccine protects murine cardiac muscle against myocardial infarction., Takahiro Kitsuka,Aya Shiraki,Jun-Ichi Oyama,Hironori Nakagami,Atsushi Tanaka,Koichi Node, Scientific reports, Vol. 12, No. 1, p. 6923-6923, 2022/04/28
プロレニンペプチドワクチンの血清、房水中の抗体価, 横田陽匡,林宏樹,高瀬公陽,花栗潤哉,渡部昌久,大野皓,小熊英隆,丸山高史,阿部雅紀,櫛山暁史,中神啓徳,山上聡,長岡泰司, 日本眼科学会雑誌, (公財)日本眼科学会, Vol. 126, No. 臨増, p. 169-169, 2022/03
眼科検査・治療の低侵襲化糖尿病網膜症診療の低侵襲化への挑戦, 長岡泰司,横田陽匡,花栗潤哉,渡部昌久,朝生浩,花崎浩継,秋山彩香,大野皓,高瀬公陽,山上聡,櫛山暁史,櫛山櫻,長井紀章,中神啓徳,林宏樹,相原一,本庄恵,蔵野信,矢冨裕,五十嵐浩二, 日本眼科学会雑誌, (公財)日本眼科学会, Vol. 126, No. 3, p. 358-387, 2022/03
RANKL Impairs the TLR4 Pathway by Increasing TRAF6 and RANK Interaction in Macrophages., Ryerson Fonseca Mota,Paulo Henrique Cavalcanti de Araújo,Maria Eduarda Ramos Cezine,Flávia Sayuri Matsuo,Rodrigo Jair Morandi Metzner,Carlos Alberto Oliveira de Biagi Junior,Kamila Chagas Peronni,Hiroki Hayashi,Munehisa Shimamura,Hironori Nakagami,Mariana Kiomy Osako, BioMed research international, Vol. 2022, p. 7740079-7740079, 2022
Immunogenicity of SARS-CoV-2 vaccination in adolescents with cardiac disease., Hiroki Hayashi,Jun Narita,Ryo Ishii,Masaki Hirose,Kazuhisa Hashimoto,Yoshiaki Yamagishi,Keiichi Ozono,Hironori Nakagami,Hidekazu Ishida, Pediatrics international : official journal of the Japan Pediatric Society, Vol. 64, No. 1, 2022/01
Brief report on a phase I/IIa study to assess the safety, tolerability, and immune response of AGMG0201 in patients with essential hypertension., Hironori Nakagami,Tetsuya Ishihama,Yuichi Daikyoji,Chieka Sasakura,Ei Yamada,Ryuichi Morishita, Hypertension research : official journal of the Japanese Society of Hypertension, SPRINGERNATURE, Vol. 45, No. 1, p. 61-65, 2022/01
Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes., Harumasa Yokota,Hiroki Hayashi,Junya Hanaguri,Satoru Yamagami,Akifumi Kushiyama,Hironori Nakagami,Taiji Nagaoka, PloS one, Vol. 17, No. 1, 2022
Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients., Xiuyuan Lu,Yuki Hosono,Masamichi Nagae,Shigenari Ishizuka,Eri Ishikawa,Daisuke Motooka,Yuki Ozaki,Nicolas Sax,Yuichi Maeda,Yasuhiro Kato,Takayoshi Morita,Ryo Shinnakasu,Takeshi Inoue,Taishi Onodera,Takayuki Matsumura,Masaharu Shinkai,Takashi Sato,Shota Nakamura,Shunsuke Mori,Teru Kanda,Emi E Nakayama,Tatsuo Shioda,Tomohiro Kurosaki,Kiyoshi Takeda,Atsushi Kumanogoh,Hisashi Arase,Hironori Nakagami,Kazuo Yamashita,Yoshimasa Takahashi,Sho Yamasaki, The Journal of experimental medicine, ROCKEFELLER UNIV PRESS, Vol. 218, No. 12, 2021/12/06
Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice, Masayoshi Suda,Ippei Shimizu,Goro Katsuumi,Yohko Yoshida,Yuka Hayashi,Ryutaro Ikegami,Naomi Matsumoto,Yutaka Yoshida,Ryuta Mikawa,Akihiro Katayama,Jun Wada,Masahide Seki,Yutaka Suzuki,Atsushi Iwama,Hironori Nakagami,Ayako Nagasawa,Ryuichi Morishita,Masataka Sugimoto,Shujiro Okuda,Masanori Tsuchida,Kazuyuki Ozaki,Mayumi Nakanishi-Matsui,Tohru Minamino, Nature Aging, Springer Science and Business Media LLC, Vol. 1, No. 12, p. 1117-1126, 2021/12
Prevention of vascular dementia via immunotherapeutic blockade of renin-angiotensin system in a rat model., Kouji Wakayama,Munehisa Shimamura,Shota Yoshida,Hiroki Hayashi,Nan Ju,Hironori Nakagami,Ryuichi Morishita, Brain research, ELSEVIER, Vol. 1772, p. 147667-147667, 2021/12/01
Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia., Hirotaka Fukami,Jun Morinaga,Hironori Nakagami,Hiroki Hayashi,Yusuke Okadome,Eiji Matsunaga,Tsuyoshi Kadomatsu,Haruki Horiguchi,Michio Sato,Taichi Sugizaki,Takashige Kuwabara,Keishi Miyata,Masashi Mukoyama,Ryuichi Morishita,Yuichi Oike, Cell reports. Medicine, Vol. 2, No. 11, p. 100446-100446, 2021/11/16
Development of COVID-19 vaccines utilizing gene therapy technology., Hironori Nakagami, International immunology, OXFORD UNIV PRESS, Vol. 33, No. 10, p. 521-527, 2021/09/25
Therapeutic vaccine for chronic diseases after the COVID-19 Era., Hironori Nakagami,Hiroki Hayashi,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, Hypertension research : official journal of the Japanese Society of Hypertension, SPRINGERNATURE, Vol. 44, No. 9, p. 1047-1053, 2021/09
The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines, Yafei Liu,Noriko Arase,Jun-ichi Kishikawa,Mika Hirose,Songling Li,Asa Tada,Sumiko Matsuoka,Akemi Arakawa,Kanako Akamatsu,Chikako Ono,Hui Jin,Kazuki Kishida,Wataru Nakai,Masako Kohyama,Atsushi Nakagawa,Yoshiaki Yamagishi,Hironori Nakagami,Atsushi Kumanogoh,Yoshiharu Matsuura,Daron M. Standley,Takayuki Kato,Masato Okada,Manabu Fujimoto,Hisashi Arase, Cold Spring Harbor Laboratory, 2021/08/23
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies., Yafei Liu,Wai Tuck Soh,Jun-Ichi Kishikawa,Mika Hirose,Emi E Nakayama,Songling Li,Miwa Sasai,Tatsuya Suzuki,Asa Tada,Akemi Arakawa,Sumiko Matsuoka,Kanako Akamatsu,Makoto Matsuda,Chikako Ono,Shiho Torii,Kazuki Kishida,Hui Jin,Wataru Nakai,Noriko Arase,Atsushi Nakagawa,Maki Matsumoto,Yukoh Nakazaki,Yasuhiro Shindo,Masako Kohyama,Keisuke Tomii,Koichiro Ohmura,Shiro Ohshima,Toru Okamoto,Masahiro Yamamoto,Hironori Nakagami,Yoshiharu Matsuura,Atsushi Nakagawa,Takayuki Kato,Masato Okada,Daron M Standley,Tatsuo Shioda,Hisashi Arase, Cell, CELL PRESS, Vol. 184, No. 13, p. 3452-3466, 2021/06/24
Prevention of Acute Lung Injury by a Novel CD14-Inhibitory Receptor Activator of the NF-κB Ligand Peptide in Mice, Nan Ju,Hiroki Hayashi,Munehisa Shimamura,Shota Yoshida,Ryo Nakamaru,Hironori Nakagami,Ryuichi Morishita,Hiromi Rakugi, ImmunoHorizons, The American Association of Immunologists, Vol. 5, No. 6, p. 438-447, 2021/06/15
Effect of prorenin peptide vaccine on an early phase of diabetic retinopathy in murine model of type 2 diabetes mellitu, Harumasa Yokota,Hiroki Hayashi,Junya Hanaguri,Satoru Yamagami,Fumiaki Kushiyama,Hironori Nakagami,Taiji Nagaoka, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Vol. 62, No. 8, 2021/06
Development of anti-thrombotic vaccine against human S100A9 in rhesus monkey., Munehisa Shimamura,Koichi Kaikita,Hironori Nakagami,Tomohiro Kawano,Nan Ju,Hiroki Hayashi,Ryo Nakamaru,Shota Yoshida,Tsutomu Sasaki,Hideki Mochizuki,Kenichi Tsujita,Ryuichi Morishita, Scientific reports, NATURE RESEARCH, Vol. 11, No. 1, p. 11472-11472, 2021/06/01
CD153 VACCINE IS A NOVEL SENOTHERAPEUTIC OPTION FOR REMOVING SENESCENCE-ASSOCIATED T CELLS, Hironori Nakagami,Shota Yoshida,Ryuichi Morishita,Hiromi Rakugi, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, p. E286-E286, 2021/04
NOVEL PATHOPHYSIOLOGICAL ROLES OF ALPHA-SYNUCLEIN (SNCA) IN AGE-RELATED VASCULAR ENDOTHELIAL DYSFUNCTION, Yoichi Takami,Hironori Nakagami,Koichi Yamamoto,Yasushi Takeya,Ryuichi Morishita,Shuko Takeda,Yasufumi Kaneda,Hiromi Rakugi, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, p. E179-E179, 2021/04
SARS-CoV-2-induced humoral immunity through B cell epitope analysis in COVID-19 infected individuals., Shota Yoshida,Chikako Ono,Hiroki Hayashi,Shinya Fukumoto,Satoshi Shiraishi,Kazunori Tomono,Hisashi Arase,Yoshiharu Matsuura,Hironori Nakagami, Scientific reports, NATURE RESEARCH, Vol. 11, No. 1, p. 5934-5934, 2021/03/15
Performance Index for Types of Clinical Research Support Service Providers for Academic Research Organizations in Japan: A Cross-Sectional Survey., Keiko Ueda,Naoto Uemura,Kotone Matsuyama,Yuji Nishizaki,Nanae Tanemura,Kento Asano,Yuki Otsuka,Naotake Yanagisawa,Toshiaki Otsuka,Shinji Yasuno,Rieko Ueda,Yumiko Seo,Hironori Nakagami,Shoji Sanada, Clinical and translational science, WILEY, Vol. 14, No. 2, p. 745-755, 2021/03
Management guideline for Werner syndrome 2020. 5. Infection associated with Werner syndrome., Toshibumi Taniguchi,Minoru Takemoto,Yoshitaka Kubota,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, WILEY, Vol. 21, No. 2, p. 150-152, 2021/02
Management guideline for Werner syndrome 2020. 7. Skin ulcer associated with Werner syndrome: Dermatological treatment., Sei-Ichiro Motegi,Minoru Takemoto,Toshibumi Taniguchi,Yoshitaka Kubota,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, WILEY, Vol. 21, No. 2, p. 160-162, 2021/02
Management guideline for Werner syndrome 2020. 4. Osteoporosis associated with Werner syndrome., Seijiro Mori,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, WILEY, Vol. 21, No. 2, p. 146-149, 2021/02
Management guideline for Werner syndrome 2020. 2. Sarcopenia associated with Werner syndrome., Masafumi Kuzuya,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Koutaro Yokote, Geriatrics & gerontology international, WILEY, Vol. 21, No. 2, p. 139-141, 2021/02
Management guideline for Werner syndrome 2020. 3. Diabetes associated with Werner syndrome., Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Kazuhisa Tsukamoto,Seijiro Mori,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, WILEY, Vol. 21, No. 2, p. 142-145, 2021/02
Management guideline for Werner syndrome 2020. 6. Skin ulcers associated with Werner syndrome: Prevention and non-surgical and surgical treatment., Yoshitaka Kubota,Minoru Takemoto,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Kazuhisa Tsukamoto,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, Vol. 21, No. 2, p. 153-159, 2021/02
Management guideline for Werner syndrome 2020 1. Dyslipidemia and fatty liver associated with Werner syndrome., Kazuhisa Tsukamoto,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Akira Taniguchi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Seijiro Mori,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, WILEY, Vol. 21, No. 2, p. 133-138, 2021/02
Management guideline for Werner syndrome 2020 8. Calcification in tendons associated with Werner syndrome., Akira Taniguchi,Yasuhito Tanaka,Minoru Takemoto,Yoshitaka Kubota,Toshibumi Taniguchi,Sei-Ichiro Motegi,Hironori Nakagami,Yoshiro Maezawa,Masaya Koshizaka,Hisaya Kato,Kazuhisa Tsukamoto,Seijiro Mori,Masafumi Kuzuya,Koutaro Yokote, Geriatrics & gerontology international, WILEY, Vol. 21, No. 2, p. 163-165, 2021/02
Anti-CoVid19 plasmid DNA vaccine induces a potent immune response in rodents by Pyro-drive Jet Injector intradermal inoculation, Tomoyuki Nishikawa,Chin Yang Chang,Jiayu A Tai,Hiroki Hayashi,Jiao Sun,Shiho Torii,Chikako Ono,Yoshiharu Matsuura,Ryoko Ide,Junichi Mineno,Miwa Sasai,Masahiro Yamamoto,Hironori Nakagami,Kunihiko Yamashita, Cold Spring Harbor Laboratory, 2021/01/14
A novel angiotensin II peptide vaccine without an adjuvant in mice., Ryo Nakamaru,Hironori Nakagami,Hiroki Hayashi,Jiao Sun,Akiko Tenma,Koichi Yamamoto,Munehisa Shimamura,Ryuichi Morishita,Hiromi Rakugi, Journal of hypertension, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, No. 1, p. 181-189, 2021/01
Time gap between the onset and diagnosis in Werner syndrome: a nationwide survey and the 2020 registry in Japan., Masaya Koshizaka,Yoshiro Maezawa,Yukari Maeda,Mayumi Shoji,Hisaya Kato,Hiyori Kaneko,Takahiro Ishikawa,Daisuke Kinoshita,Kazuki Kobayashi,Junji Kawashima,Akiko Sekiguchi,Sei-Ichiro Motegi,Hironori Nakagami,Yoshihiko Yamada,Shinji Tsukamoto,Akira Taniguchi,Ken Sugimoto,Yukiko Shoda,Kunihiko Hashimoto,Toru Yoshimura,Daisuke Suzuki,Masafumi Kuzuya,Minoru Takemoto,Koutaro Yokote, Aging, Vol. 12, No. 24, p. 24940-24956, 2020/12/29
Prevention of Progression of Aortic Aneurysm by Peptide Vaccine Against Ang II (Angiotensin II) in a Rat Model., Tomohiro Kurashiki,Takashi Miyake,Hironori Nakagami,Motonobu Nishimura,Ryuichi Morishita, Hypertension (Dallas, Tex. : 1979), Vol. 76, No. 6, p. 1879-1888, 2020/12
Future Directions of Therapeutic Vaccines for Chronic Diseases., Ryo Nakamaru,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, Circulation journal : official journal of the Japanese Circulation Society, JAPANESE CIRCULATION SOC, Vol. 84, No. 11, p. 1895-1902, 2020/10/23
Progress of Gene Therapy in Cardiovascular Disease., Munehisa Shimamura,Hironori Nakagami,Fumihiro Sanada,Ryuichi Morishita, Hypertension (Dallas, Tex. : 1979), LIPPINCOTT WILLIAMS & WILKINS, Vol. 76, No. 4, p. 1038-1044, 2020/10
脊椎関節炎をターゲットとしたIL17Aワクチンの薬効の検討, 林宏樹,孫嬌,柳田結花,冨田哲也,森下竜一,中神啓徳, 日本抗加齢医学会総会プログラム・抄録集, (一社)日本抗加齢医学会, Vol. 20回, p. 240-240, 2020/09
Antiproliferative Effects of Monoclonal Antibodies against (Pro)Renin Receptor in Pancreatic Ductal Adenocarcinoma., Asadur Rahman,Makoto Matsuyama,Akio Ebihara,Yuki Shibayama,Arif Ul Hasan,Hironori Nakagami,Fumiaki Suzuki,Jiao Sun,Tomoe Kobayashi,Hiroki Hayashi,Daisuke Nakano,Hideki Kobara,Tsutomu Masaki,Akira Nishiyama, Molecular cancer therapeutics, American Association for Cancer Research (AACR), Vol. 19, No. 9, p. 1844-1855, 2020/09
The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice., Shota Yoshida,Hironori Nakagami,Hiroki Hayashi,Yuka Ikeda,Jiao Sun,Akiko Tenma,Hideki Tomioka,Tomohiro Kawano,Munehisa Shimamura,Ryuichi Morishita,Hiromi Rakugi, Nature communications, Springer Science and Business Media LLC, Vol. 11, No. 1, p. 2482-2482, 2020/05/18
Further Development and Intra-Laboratory Validation of a Novel Pyro-Drive Jet Injector (PJI), Kunihiko Yamashita,Chinyang Chang,Jiayu A. Tai,Jiao Sun,Hiroki Hayashi,Hiroshi Miyazaki,Hironori Nakagami,Yasufumi Kaneda, MOLECULAR THERAPY, CELL PRESS, Vol. 28, No. 4, p. 294-294, 2020/04
[Current status and perspectives in the development of therapeutic agents targeting post-ischemic inflammation in the acute stage of stroke]., Munehisa Shimamura,Hironori Nakagami,Tsutomu Sasaki,Ryuichi Morishita,Hideki Mochizuki, Rinsho shinkeigaku = Clinical neurology, Vol. 60, No. 4, p. 253-259, 2020/03/31
Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice., Hiroshi Koriyama,Yuka Ikeda,Hironori Nakagami,Munehisa Shimamura,Shota Yoshida,Hiromi Rakugi,Ryuichi Morishita, Vaccines, Vol. 8, No. 1, 2020/02/12
The Efficacy of Angiotensin II Peptide Vaccination Against White Matter Lesions of Vascular Dementia in Rats, Kouji Wakayama,Munehisa Shimamura,Hironori Nakagami,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 51, 2020/02
Cellular senescence and senescence-associated T cells as a potential therapeutic target., Hironori Nakagami, Geriatrics & gerontology international, WILEY, Vol. 20, No. 2, p. 97-100, 2020/02
Combined Analysis of Clinical Data on HGF Gene Therapy to Treat Critical Limb Ischemia in Japan., Ryuichi Morishita,Munehisa Shimamura,Yasushi Takeya,Hironori Nakagami,Mitsuaki Chujo,Tetsuya Ishihama,Ei Yamada,Hiromi Rakugi, Current gene therapy, BENTHAM SCIENCE PUBL LTD, Vol. 20, No. 1, p. 25-35, 2020
Novel properties of myoferlin in glucose metabolism via pathways involving modulation of adipose functions., Nozato Y,Takami Y,Yamamoto K,Nagasawa M,Nozato S,Imaizumi Y,Takeshita H,Cheng W,Ito Y,Takeda S,Takeya Y,Sugimoto K,Nakagami H,Hanayama R,Rakugi H, FASEB J., WILEY, Vol. 34, No. 2, p. 2792-2811, 2020/01
Stable Immune Response Induced by Intradermal DNA Vaccination by a Novel Needleless Pyro-Drive Jet Injector., Chinyang Chang,Jiao Sun,Hiroki Hayashi,Ayano Suzuki,Yuko Sakaguchi,Hiroshi Miyazaki,Tomoyuki Nishikawa,Hironori Nakagami,Kunihiko Yamashita,Yasufumi Kaneda, AAPS PharmSciTech, Vol. 21, No. 1, p. 19-19, 2019/12/09
AJP001, a novel helper T-cell epitope, induces a humoral immune response with activation of innate immunity when included in a peptide vaccine., Akiko Tenma,Hironori Nakagami,Hideki Tomioka,Makoto Sakaguchi,Ryoko Ide,Hiroshi Koriyama,Hiroki Hayashi,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, FASEB bioAdvances, Vol. 1, No. 12, p. 760-772, 2019/12
Investigator-initiated clinical study of a functional peptide, SR-0379, for limb ulcers of patients with Werner syndrome as a pilot study., Hironori Nakagami,Ken Sugimoto,Takahiro Ishikawa,Masaya Koshizaka,Taku Fujimoto,Eiji Kiyohara,Misa Hayashi,Yukinobu Nakagawa,Hiroshi Ando,Yuta Terabe,Yoichi Takami,Koichi Yamamoto,Yasushi Takeya,Minoru Takemoto,Tamotsu Ebihara,Ayumi Nakamura,Mitsunori Nishikawa,Xiang Jing Yao,Hideki Hanaoka,Koutaro Yokote,Hiromi Rakugi, Geriatrics & gerontology international, WILEY, Vol. 19, No. 11, p. 1118-1123, 2019/11
Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis., Nan Ju,Munehisa Shimamura,Hiroki Hayashi,Yuka Ikeda,Shota Yoshida,Ayumi Nakamura,Ryuichi Morishita,Hiromi Rakugi,Hironori Nakagami, Scientific reports, Vol. 9, No. 1, p. 15434-15434, 2019/10/28
Serum albumin/globulin ratio is associated with cognitive function in community-dwelling older people: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study., Maeda S,Takeya Y,Oguro R,Akasaka H,Ryuno H,Kabayama M,Yokoyama S,Nagasawa M,Fujimoto T,Takeda M,Onishi-Takeya M,Itoh N,Takami Y,Yamamoto K,Sugimoto K,Inagaki H,Ogawa M,Nakagawa T,Yasumoto S,Masui Y,Arai Y,Ishizaki T,Ikebe K,Gondo Y,Kamide K,Rakugi H, Geriatrics & gerontology international, Vol. 19, No. 10, p. 967-971, 2019/10
A vaccine targeting blood clot formation: what is the potential?, Shimamura M,Nakagami H, Expert review of vaccines, TAYLOR & FRANCIS LTD, Vol. 18, No. 5, p. 419-421, 2019/05
Peptide vaccine for semaphorin3E ameliorates systemic glucose intolerance in mice with dietary obesity., Yohko Yoshida,Ippei Shimizu,Yuka Hayashi,Ryutaro Ikegami,Masayoshi Suda,Goro Katsuumi,Takayuki Wakasugi,Masaaki Nakao,Hironori Nakagami,Ryuichi Morishita,Tohru Minamino, Scientific reports, NATURE PUBLISHING GROUP, Vol. 9, No. 1, p. 3858-3858, 2019/03/07
Association between long-term care and chronic and lifestyle-related disease modified by social profiles in community-dwelling people aged 80 and 90; SONIC study., Kiyoshige E,Kabayama M,Gondo Y,Masui Y,Ryuno H,Sawayama Y,Inoue T,Akagi Y,Sekiguchi T,Tanaka K,Nakagawa T,Yasumoto S,Ogawa M,Inagaki H,Oguro R,Sugimoto K,Akasaka H,Yamamoto K,Takeya Y,Takami Y,Itoh N,Takeda M,Nagasawa M,Yokoyama S,Maeda S,Ikebe K,Arai Y,Ishizaki T,Rakugi H,Kamide K, Archives of gerontology and geriatrics, Vol. 81, p. 176-181, 2019/03
Dysfunctional high density lipoprotein failed to rescue the function of oxidized low density lipoprotein-treated endothelial progenitor cells: a novel index for the prediction of HDL functionality., Chun-Ming Shih,Feng-Yen Lin,Jong-Shiuan Yeh,Yi-Wen Lin,Shih-Hurng Loh,Nai-Wen Tsao,Hironori Nakagami,Ryuichi Morishita,Tatsuya Sawamura,Chi-Yuan Li,Cheng-Yen Lin,Chun-Yao Huang, Translational research : the journal of laboratory and clinical medicine, ELSEVIER SCIENCE INC, Vol. 205, p. 17-32, 2019/03
[Development of therapeutic vaccine for life style-related diseases]., Hironori Nakagami, Nihon yakurigaku zasshi. Folia pharmacologica Japonica, Vol. 154, No. 5, p. 270-274, 2019
Temporal and spatial profile of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in ischemic stroke in mice., Kawano T,Shimamura M,Nakagami H,Kanki H,Sasaki T,Mochizuki H, PloS one, Vol. 14, No. 5, 2019
Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis., Imaizumi Y,Takami Y,Yamamoto K,Nagasawa M,Nozato Y,Nozato S,Takeshita H,Wang C,Yokoyama S,Hayashi H,Hongyo K,Akasaka H,Takeya Y,Sugimoto K,Nakagami H,Rakugi H, Biochemical and biophysical research communications, Vol. 508, No. 4, p. 1168-1174, 2019/01
新規機能性ペプチドを用いた皮膚潰瘍治療薬の臨床開発, 中神啓徳,杉本研,鷹見洋一,藤本拓,樂木宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 94, No. 4, p. 1560-1560, 2018/12
Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke., Shimamura M,Nakagami H,Shimizu H,Mukai H,Watanabe R,Okuzono T,Kawano T,Ikeda Y,Hayashi H,Yoshida S,Ju N,Mochizuki H,Morishita R, Scientific reports, NATURE PUBLISHING GROUP, Vol. 8, No. 1, p. 17770-17770, 2018/12
Therapeutic Vaccine Against S100A9 (S100 Calcium-Binding Protein A9) Inhibits Thrombosis Without Increasing the Risk of Bleeding in Ischemic Stroke in Mice., Kawano T,Shimamura M,Nakagami H,Iso T,Koriyama H,Takeda S,Baba K,Sasaki T,Sakaguchi M,Morishita R,Mochizuki H, Hypertension (Dallas, Tex. : 1979), Vol. 72, No. 6, p. 1355-1364, 2018/12
Recent Advances in Therapeutic Vaccines to Treat Hypertension., Hironori Nakagami,Ryuichi Morishita, Hypertension (Dallas, Tex. : 1979), LIPPINCOTT WILLIAMS & WILKINS, Vol. 72, No. 5, p. 1031-1036, 2018/11
MYOFERLIN-MEDIATED LYSOSOMAL EXOCYTOSIS OF MACROPHAGE REGULATES OBESITY-INDUCED ADIPOSE INFLAMMATION, Yoichi Nozato,Yoichi Takami,Hironori Nakagami,Koichi Yamamoto,Rikinari Hanayama, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 36, p. E80-E80, 2018/10
Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice., Hikari Takeshita,Koichi Yamamoto,Satoko Nozato,Masao Takeda,So-Ichiro Fukada,Tadakatsu Inagaki,Hirotsugu Tsuchimochi,Mikiyasu Shirai,Yoichi Nozato,Taku Fujimoto,Yuki Imaizumi,Serina Yokoyama,Motonori Nagasawa,Go Hamano,Kazuhiro Hongyo,Tatsuo Kawai,Hiroko Hanasaki-Yamamoto,Shuko Takeda,Toshimasa Takahashi,Hiroshi Akasaka,Norihisa Itoh,Yoichi Takami,Yasushi Takeya,Ken Sugimoto,Hironori Nakagami,Hiromi Rakugi, Journal of cachexia, sarcopenia and muscle, WILEY, Vol. 9, No. 5, p. 975-986, 2018/10
プロレニンを標的とした治療ワクチンの2型糖尿病モデルでの基礎的検討, 横田陽匡,林宏樹,長岡泰司,吉田晃敏,中神啓徳, 日本眼科学会雑誌, (公財)日本眼科学会, Vol. 122, No. 臨増, p. 237-237, 2018/03
Pathophysiology of cardiovascular disease in diabetes mellitus., Gerardo Rodriguez-Araujo,Hironori Nakagami, Cardiovascular endocrinology & metabolism, LIPPINCOTT WILLIAMS & WILKINS, Vol. 7, No. 1, p. 4-9, 2018/03
Development of a novel and feasible antibody therapy targeting vasohibin-2, EunSeo Lee,Yasuhiro Suzuki,Hironori Nakagami,Hideki Tomioka,Yasufumi Sato, CANCER SCIENCE, WILEY, Vol. 109, p. 286-286, 2018/01
Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice., Shimamura M,Nakagami H,Shimizu H,Wakayama K,Kawano T,Ikeda Y,Hayashi H,Yoshida S,Mochizuki H,Morishita R, BioMed research international, HINDAWI LTD, Vol. 2018, p. 4637084-4637084, 2018
Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice., Ryo Kawakami,Yoichi Nozato,Hironori Nakagami,Yuka Ikeda,Munehisa Shimamura,Shota Yoshida,Jiao Sun,Tomohiro Kawano,Yoichi Takami,Takahisa Noma,Hiromi Rakugi,Tetsuo Minamino,Ryuichi Morishita, PloS one, Vol. 13, No. 2, 2018
Physician-initiated clinical study of limb ulcers treated with a functional peptide, SR-0379: from discovery to a randomized, double-blind, placebo-controlled trial., Hironori Nakagami,Ken Sugimoto,Takahiro Ishikawa,Taku Fujimoto,Toshifumi Yamaoka,Misa Hayashi,Eiji Kiyohara,Hiroshi Ando,Yuta Terabe,Yoichi Takami,Koichi Yamamoto,Yasushi Takeya,Minoru Takemoto,Masaya Koshizaka,Tamotsu Ebihara,Ayumi Nakamura,Mitsunori Nishikawa,Xiang Jing Yao,Hideki Hanaoka,Ichiro Katayama,Koutaro Yokote,Hiromi Rakugi, NPJ aging and mechanisms of disease, NATURE RESEARCH, Vol. 4, p. 2-2, 2018
Association between renin-angiotensin-aldosterone system blockade and future osteoporotic fracture risk in hypertensive population A population-based cohort study in Taiwan, Chang-I. Chen,Jong-Shiuan Yeh,Nai-Wen Tsao,Fen-Yen Lin,Chun-Ming Shih,Kuang-Hsing Chiang,Yung-Ta Kao,Yu-Ann Fang,Lung-Wen Tsai,Wen-Chi Liu,Hironori Nakagami,Ryuichi Morishita,Yi-Jie Kuo,Chun-Yao Huang, MEDICINE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 96, No. 46, 2017/11
Physician-initiated first-in-human clinical study using a novel angiogenic peptide, AG30/5C, for patients with severe limb ulcers, Hironori Nakagami,Toshifumi Yamaoka,Misa Hayashi,Atsushi Tanemura,Yasushi Takeya,Hitomi Kurinami,Ken Sugimoto,Ayumi Nakamura,Kazunori Tomono,Katsuto Tamai,Ichiro Katayama,Hiromi Rakugi,Yasufumi Kaneda, GERIATRICS & GERONTOLOGY INTERNATIONAL, WILEY, Vol. 17, No. 11, p. 2150-2156, 2017/11
糖尿病の新規バイオマーカーとしてのGFAPの解析(Glial Fibrillary Acidic Protein(GFAP) is a Novel Biomarker for Autoimmune Diabetes), 中神啓徳,楽木宏実,鷹見洋一,森下竜一, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 40回, p. 365-365, 2017/10
Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes, Zhengda Pang,Akifumi Kushiyama,Jiao Sun,Takako Kikuchi,Hiroki Yamazaki,Yasuhiko Iwamoto,Hiroshi Koriyama,Shota Yoshida,Munehisa Shimamura,Masayoshi Higuchi,Tomohiro Kawano,Yoichi Takami,Hiromi Rakugi,Ryuichi Morishita,Hironori Nakagami, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 31, No. 9, p. 4053-4063, 2017/09
Design of therapeutic vaccines as a novel antibody therapy for cardiovascular diseases, Hironori Nakagami, JOURNAL OF CARDIOLOGY, ELSEVIER SCIENCE BV, Vol. 70, No. 3-4, p. 201-205, 2017/09
Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress, Kouji Wakayama,Munehisa Shimamura,Jun-ichi Suzuki,Ryo Watanabe,Hiroshi Koriyama,Hiroshi Akazawa,Hironori Nakagami,Hideki Mochizuki,Mitsuaki Isobe,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 5, p. 1362-+, 2017/05
Fundamental study on gene transfer utilizing magnetic force and jet injector, T. Hasegawa,H. Nakagami,Y. Akiyama,S. Nishijima, Progress in Superconductivity and Cryogenics (PSAC), Vol. 19, No. 1, p. 9-12, 2017/03
A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction, Ryo Watanabe,Jun-ichi Suzuki,Kouji Wakayama,Yasuhiro Maejima,Munehisa Shimamura,Hiroshi Koriyama,Hironori Nakagami,Hidetoshi Kumagai,Yuichi Ikeda,Hiroshi Akazawa,Ryuichi Morishita,Issei Komuro,Mitsuaki Isobe, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 7, p. 43920-43920, 2017/03
New treatment, Munehisa Shimamura,Hironori Nakagami,Kouji Wakayama,Tomohiro Kawano,Hideki Mochizuki,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, 2017/02
A novel lipoprotein (A) lowering drug, D-47, decreases neointima thickening after vascular injury, Yutaka Nakaya,Daiju Fukuda,Takashi Oyamada,Kazuo Ogawa,Nagakatsu Harada,Hironori Nakagami,Ryuichi Morishita,Masataka Sata,Hiroshi Sakaue, Journal of Medical Investigation, University of Tokushima, Vol. 64, No. 1-2, p. 64-67, 2017
Evaluating the potential of the GFAP-KLH immune-tolerizing vaccine for type 1 diabetes in mice, Zhengda Pang,Masayoshi Higuchi,Hiroshi Koriyama,Shota Yoshida,Hitomi Kurinami,Munehisa Shimamura,Yoichi Takami,Hiromi Rakugi,Ryuichi Morishita,Hironori Nakagami, FEBS LETTERS, WILEY-BLACKWELL, Vol. 591, No. 1, p. 129-136, 2017/01
A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke, Hitomi Kurinami,Munehisa Shimamura,Hironori Nakagami,Hideo Shimizu,Hiroshi Koriyama,Tomohiro Kawano,Kouji Wakayama,Hideki Mochizuki,Hiromi Rakugi,Ryuichi Morishita, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 6, p. 38062-38062, 2016/11
DEVELOP A THERAPEUTIC VACCINE FOR ANGIOTENSIN II, Hironori Nakagami,Hiroshi Koriyama,Tomohiro Katsuya,Hiromi Rakugi,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 34, p. E222-E222, 2016/09
NOVEL THERAPEUTIC APPROACH FOR CEREBRAL ISCHEMIA IN RATS WITH ANGIOTENSIN II PEPTIDE VACCINE, Hironori Nakagami,Kouji Wakayama,Munehisa Shimamura,Jun-ichi Suzuki,Ryo Watanabe,Hiroshi Koriyama,Mitsuaki Isobe,Hiromi Rakugi,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 34, p. E408-E408, 2016/09
RANKL system in vascular and valve calcification with aging., Ryo Kawakami,Hironori Nakagami,Takahisa Noma,Koji Ohmori,Masakazu Kohno,Ryuichi Morishita, Inflammation and regeneration, Vol. 36, p. 10-10, 2016
加齢に伴う動脈硬化形成過程における脱ユビキチン化酵素CYLD(cylindromatosis)のマクロファージの泡沫化への影響, 今泉友希,鷹見洋一,中神啓徳,山本浩一,樂木宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 91, No. 2, p. 637-637, 2015/09
Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor, Koichi Yamamoto,Akemi Kakino,Hikari Takeshita,Norihiro Hayashi,Lei Li,Atsushi Nakano,Hiroko Hanasaki-Yamamoto,Yoshiko Fujita,Yuki Imaizumi,Serina Toyama-Yokoyama,Chikako Nakama,Tatsuo Kawai,Masao Takeda,Kazuhiro Hongyo,Ryosuke Oguro,Yoshihiro Maekawa,Norihisa Itoh,Yoichi Takami,Miyuki Onishi,Yasushi Takeya,Ken Sugimoto,Kei Kamide,Hironori Nakagami,Mitsuru Ohishi,Theodore W. Kurtz,Tatsuya Sawamura,Hiromi Rakugi, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 29, No. 8, p. 3342-3356, 2015/08
Effect of angiotensinII receptor blocker, olmesartan, on turnover of bone metabolism in bedridden elderly hypertensive women with disuse syndrome, Motokuni Aoki,Hirohisa Kawahata,Daisuke Sotobayashi,Hisahiro Yu,Atsushi Moriguchi,Hironori Nakagami,Toshio Ogihara,Ryuichi Morishita, GERIATRICS & GERONTOLOGY INTERNATIONAL, WILEY-BLACKWELL, Vol. 15, No. 8, p. 1064-1072, 2015/08
From discovery of novel antimicrobial peptide to clinical trial for drug development in wound repair, Hironori Nakagami, JOURNAL OF PHARMACOLOGICAL SCIENCES, JAPANESE PHARMACOLOGICAL SOC, Vol. 128, No. 3, p. S114-S114, 2015/07
Low alpha-synuclein levels in the blood are associated with insulin resistance, Gerardo Rodriguez-Araujo,Hironori Nakagami,Yoichi Takami,Tomohiro Katsuya,Hiroshi Akasaka,Shigeyuki Saitoh,Kazuaki Shimamoto,Ryuichi Morishita,Hiromi Rakugi,Yasufumi Kaneda, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 5, p. 12081-12081, 2015/07
Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats, Hiroshi Koriyama,Hironori Nakagami,Futoshi Nakagami,Mariana Kiomy Osako,Mariko Kyutoku,Munehisa Shimamura,Hitomi Kurinami,Tomohiro Katsuya,Hiromi Rakugi,Ryuichi Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 66, No. 1, p. 167-174, 2015/07
Disease-associated polymorphisms in 9p21 are not associated with extreme longevity., Congrains A,Kamide K,Hirose N,Arai Y,Oguro R,Nakama C,Imaizumi Y,Kawai T,Kusunoki H,Yamamoto H,Onishi-Takeya M,Takeya Y,Yamamoto K,Sugimoto K,Akasaka H,Saitoh S,Miura T,Awata N,Kato N,Katsuya T,Ikebe K,Gondo Y,Rakugi H, Geriatrics & gerontology international, Vol. 15, No. 6, p. 797-803, 2015/06
Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse, Hirohisa Kawahata,Daisuke Sotobayashi,Motokuni Aoki,Hideo Shimizu,Hironori Nakagami,Toshio Ogihara,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 38, No. 6, p. 382-393, 2015/06
The Biphasic Effects of Oxidized-Low Density Lipoprotein on the Vasculogenic Function of Endothelial Progenitor Cells, Feng-Yen Lin,Nai-Wen Tsao,Chun-Ming Shih,Yi-Wen Lin,Jong-Shiua Yeh,Jaw-Wen Chen,Hironori Nakagami,Ryuichi Morishita,Tatsuya Sawamura,Chun-Yao Huang, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 10, No. 5, 2015/05
Evaluation of the Genetic Risk of Hypertension-Related Diseases, Hironori Nakagami, CIRCULATION JOURNAL, JAPANESE CIRCULATION SOC, Vol. 79, No. 4, p. 756-757, 2015/04
Development of DNA vaccines as an anti-hypertensive therapy or for anti-angiogenesis, Hironori Nakagami,Ryuichi Morishita, EXPERT OPINION ON BIOLOGICAL THERAPY, TAYLOR & FRANCIS LTD, Vol. 15, No. 3, p. 431-436, 2015/03
Teneligliptin: expectations for its pleiotropic action, Ryuichi Morishita,Hironori Nakagami, EXPERT OPINION ON PHARMACOTHERAPY, INFORMA HEALTHCARE, Vol. 16, No. 3, p. 417-426, 2015/02
Molecular mechanism of vascular calcification with aging, NAKAGAMI Hironori, Blood & Vessel, The Japanese Society on Thrombosis and Hemostasis, Vol. 26, No. 3, p. 284-289, 2015
Prevention of Neointimal Formation After Angioplasty Using Nuclear Factor-kappa B Decoy Oligodeoxynucleotide-Coated Balloon Catheter in Rabbit Model, Takashi Miyake,Shinya Ihara,Tetsuo Miyake,Yusuke Tsukada,Hajime Watanabe,Hiroaki Matsuda,Hideki Kiguchi,Hiroyuki Tsujimoto,Hironori Nakagami,Ryuichi Morishita, CIRCULATION-CARDIOVASCULAR INTERVENTIONS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 7, No. 6, p. 787-796, 2014/12
Peptide vaccines for hypertension and diabetes mellitus, Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, Vaccines, MDPI AG, Vol. 2, No. 4, p. 832-840, 2014/11/26
Gene therapy for peripheral arterial disease, Munehisa Shimamura,Hironori Nakagami,Yoshiaki Taniyama,Ryuichi Morishita, EXPERT OPINION ON BIOLOGICAL THERAPY, INFORMA HEALTHCARE, Vol. 14, No. 8, p. 1175-1184, 2014/08
[Bone metabolism and cardiovascular function update. Cross link of hypertension, bone loss and vascular calcification - common back grounds in renin angiotensin system with anti-aging aspect -]., Shimizu H,Nakagami H,Morishita R,Clinical calcium, Clinical calcium, Vol. 24, No. 7, p. 53-62, 2014/07
The dipeptidyl peptidase-4 inhibitor teneligliptin improved endothelial dysfunction and insulin resistance in the SHR/NDmcr-cp rat model of metabolic syndrome, Hironori Nakagami,Zhengda Pang,Takashi Shimosato,Toshinori Moritani,Hitomi Kurinami,Hiroshi Koriyama,Akiko Tenma,Munehisa Shimamura,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 37, No. 7, p. 629-635, 2014/07
禿頭自然発症ラットをもちいた禿頭遺伝子解析へのアプローチ, 志水秀郎,中神啓徳,山田秀和,勝谷友宏,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, (一社)日本抗加齢医学会, Vol. 14回, p. 348-348, 2014/06
OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice, Munehisa Shimamura,Hironori Nakagami,Mariana K. Osako,Hitomi Kurinami,Hiroshi Koriyama,Pang Zhengda,Hideki Tomioka,Akiko Tenma,Kouji Wakayama,Ryuichi Morishita, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 111, No. 22, p. 8191-8196, 2014/06
Long-term expression of periostin during the chronic stage of ischemic stroke in mice, Munehisa Shimamura,Yoshiaki Taniyama,Hironori Nakagami,Naruto Katsuragi,Kouji Wakayama,Hiroshi Koriyama,Hitomi Kurinami,Akiko Tenma,Hideki Tomioka,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 37, No. 6, p. 494-499, 2014/06
Therapeutic vaccine against DPP4 improves glucose metabolism in mice, Zhengda Pang,Hironori Nakagami,Mariana K. Osako,Hiroshi Koriyama,Futoshi Nakagami,Hideki Tomioka,Munehisa Shimamura,Hitomi Kurinami,Yoichi Takami,Ryuichi Morishita,Hiromi Rakugi, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 111, No. 13, p. E1256-E1263, 2014/04
Therapeutic Vaccines for Hypertension and Dyslipidemia, Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, INTERNATIONAL HEART JOURNAL, INT HEART JOURNAL ASSOC, Vol. 55, No. 2, p. 96-100, 2014/03
Novel Anti-Microbial Peptide SR-0379 Accelerates Wound Healing via the PI3 Kinase/Akt/mTOR Pathway, Hideki Tomioka,Hironori Nakagami,Akiko Tenma,Yoshimi Saito,Toshihiro Kaga,Toshihide Kanamori,Nao Tamura,Kazunori Tomono,Yasufumi Kaneda,Ryuichi Morishita, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 9, No. 3, 2014/03
Development of LC-MS/MS quantification of the novel antimicrobial peptide, SR-0379, and its pharmacokinetics in rats, Hideki Tomioka,Hironori Nakagami,Tomokazu Sano,Kazuaki Takafuji,Seiji Takashima,Yasufumi Kaneda,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Bentham Science Publishers B.V., Vol. 14, No. 1, p. 26-31, 2014
糖代謝におけるレニン・アンジオテンシン系の役割, 志水秀郎,中神啓徳,森下竜一, Anti-aging Science, (株)メディカルレビュー社, Vol. 5, No. 3, p. 231-231, 2013/12
GEANE study group; HOMED-BP study group. Genome-wide response to antihypertensive medication using home blood pressure measurements: a pilot study nested within the HOMED-BP study., Kamide K,Asayama K,Katsuya T,Ohkubo T,Hirose T,Inoue R,Metoki H,Kikuya M,Obara T,Hanada H,Thijs L,Kuznetsova T,Noguchi Y,Sugimoto K,Ohishi M,Morimoto S,Nakahashi T,Takiuchi S,Ishimitsu T,Tsuchihashi T,Soma M,Higaki J,Matsuura H,Shinagawa T,Sasaguri T,Miki T,Takeda K,Shimamoto K,Ueno M,Hosomi N,Kato J,Komai N,Kojima S,Sase K,Miyata T,Tomoike H,Kawano Y,Ogihara T,Rakugi H,Staessen JA,Imai Y, Pharmacogenomics, FUTURE MEDICINE LTD, Vol. 14, No. 14, p. 1709-1721, 2013/11
Development of novel DNA vaccine for VEGF in murine cancer model, Mariko Kyutoku,Hironori Nakagami,Hiroshi Koriyama,Hideki Tomioka,Futoshi Nakagami,Munehisa Shimamura,Hitomi Kurinami,Pang Zhengda,Dong Hyun Jo,Jeong Hun Kim,Nobuyuki Takakura,Ryuichi Morishita, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 3, 2013/11
マウスのDPP4に対する治療用ワクチンの有効性と安全性(Effectiveness and safety of a therapeutic vaccine against DPP4 in mice), Pang Zhengda,中神啓徳,Osako Mariana Kiomy,郡山弘,鷹見洋一,樂木宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 89, No. 2, p. 756-756, 2013/09
Unique remodeling processes after vascular injury in intracranial arteries: analysis using a novel mouse model, Munehisa Shimamura,Hironori Nakagami,Masataka Sata,Minoru Takaoka,Junya Azuma,Mariana Kiomy Osako,Hiroshi Koriyama,Hitomi Kurinami,Kouji Wakayama,Takashi Miyake,Ryuichi Morishita, JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, NATURE PUBLISHING GROUP, Vol. 33, No. 8, p. 1153-1159, 2013/08
アクリジン・オレンジを用いた破骨細胞酸産生能評価による各種降圧剤のスクリーニング, 志水秀郎,中神啓徳,尾崎和成,楠博,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, (一社)日本抗加齢医学会, Vol. 13回, p. 239-239, 2013/06
Do Angiotensin Receptor Blockers Protect Against Alzheimer's Disease?, Hitomi Kurinami,Munehisa Shimamura,Naoyuki Sato,Hironori Nakagami,Ryuichi Morishita, DRUGS & AGING, ADIS INT LTD, Vol. 30, No. 6, p. 367-372, 2013/06
Cross-Talk of Receptor Activator of Nuclear Factor-kappa B Ligand Signaling With Renin-Angiotensin System in Vascular Calcification, Mariana Kiomy Osako,Hironori Nakagami,Munehisa Shimamura,Hiroshi Koriyama,Futoshi Nakagami,Hideo Shimizu,Takashi Miyake,Masao Yoshizumi,Hiromi Rakugi,Ryuichi Morishita, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 33, No. 6, p. 1287-+, 2013/06
Potential Effect of Angiotensin II Receptor Blockade in Adipose Tissue and Bone, Hironori Nakagami,Mariana Kiomy Osako,Ryuichi Morishita, CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBL LTD, Vol. 19, No. 17, p. 3049-3053, 2013/05
Inhibition of Neointima Formation through DNA Vaccination for Apolipoprotein(a): A New Therapeutic Strategy for Lipoprotein(a), Mariko Kyutoku,Hironori Nakagami,Hiroshi Koriyama,Futoshi Nakagami,Munehisa Shimamura,Hitomi Kurinami,Hideki Tomioka,Takashi Miyake,Tomohiro Katsuya,Ryuichi Morishita, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 3, 2013/04
[Hypertension and osteoporosis]., Nakagami H,Morishita R,Clinical calcium, Vol. 23, No. 4, p. 497-503, 2013/04
The mechanism of white and brown adipocyte differentiation, Hironori Nakagami, Diabetes and Metabolism Journal, KOREAN DIABETES ASSOC, Vol. 37, No. 2, p. 85-90, 2013/04
Human gene therapy in cardiovascular diseases, Mariana Kiomy Osako,Hironori Nakagami,Ryuichi Morishita, Gene Therapy: Technologies and Applications, Future Medicine Ltd., p. 85-93, 2013/03/01
Decrease in Blood Pressure and Regression of Cardiovascular Complications by Angiotensin II Vaccine in Mice, Futoshi Nakagami,Hiroshi Koriyama,Hironori Nakagami,Mariana Kiomy Osako,Munehisa Shimamura,Mariko Kyutoku,Takashi Miyake,Tomohiro Katsuya,Hiromi Rakugi,Ryuichi Morishita, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 8, No. 3, 2013/03
Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway, Gerardo Rodriguez-Araujo,Hironori Nakagami,Hiroki Hayashi,Masaki Mori,Tetsuya Shiuchi,Yasuhiko Minokoshi,Yoshikazu Nakaoka,Yoichi Takami,Issei Komuro,Ryuichi Morishita,Yasufumi Kaneda, Cellular and Molecular Life Sciences, SPRINGER BASEL AG, Vol. 70, No. 6, p. 1123-1133, 2013/03
The Transcription Factors Tbx18 and Wt1 Control the Epicardial Epithelial-Mesenchymal Transition through Bi-Directional Regulation of Slug in Murine Primary Epicardial Cells, Makiko Takeichi,Keisuke Nimura,Masaki Mori,Hironori Nakagami,Yasufumi Kaneda, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 8, No. 2, 2013/02
Olmesartan reduces pentosidine production and ameliorates fragility of bone in ovariectomized fructose-fed rats, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Osako Kiomy Mariana,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 13, No. 2, p. 150-158, 2013
Lymphedema and Therapeutic Lymphangiogenesis, Yukihiro Saito,Hironori Nakagami,Yasufumi Kaneda,Ryuichi Morishita, BIOMED RESEARCH INTERNATIONAL, HINDAWI PUBLISHING CORPORATION, Vol. 2013, 2013
Gene Therapy and Cell-Based Therapies for Therapeutic Angiogenesis in Peripheral Artery Disease, Munehisa Shimamura,Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, BIOMED RESEARCH INTERNATIONAL, HINDAWI PUBLISHING CORPORATION, Vol. 2013, 2013
Therapeutic Effect of Ribbon-Type Nuclear Factor-kappa B Decoy Oligonucleotides in a Rat Model of Inflammatory Bowel Disease, Kazunari Ozaki,Hirofumi Makino,Motokuni Aoki,Takashi Miyake,Natsuki Yasumasa,Mariana Kiomy Osako,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, CURRENT GENE THERAPY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 6, p. 484-492, 2012/12
Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells, Chun-Yao Huang,Chun-Ming Shih,Nai-Wen Tsao,Yi-Wen Lin,Po-Hsun Huang,Shinn-Chih Wu,Ai-Wei Lee,Yung-Ta Kao,Nen-Chung Chang,Hironori Nakagami,Ryuichi Morishita,Keng-Liang Ou,Wen-Chi Hou,Cheng-Yen Lin,Kuo-Gi Shyu,Feng-Yen Lin, BRITISH JOURNAL OF PHARMACOLOGY, WILEY, Vol. 167, No. 7, p. 1506-1519, 2012/12
Moderate to High Concentrations of High-Density Lipoprotein From Healthy Subjects Paradoxically Impair Human Endothelial Progenitor Cells and Related Angiogenesis by Activating Rho-Associated Kinase Pathways, Chun-Yao Huang,Feng-Yen Lin,Chun-Ming Shih,Heng-Kien Au,Yu-Jia Chang,Hironori Nakagami,Ryuichi Morishita,Nen-Chung Chang,Kou-Gi Shyu,Jaw-Wen Chen, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 32, No. 10, p. 2405-2417, 2012/10
[Activation of osteoclasts by RAAS and strategy of target therapy on bone metabolic diseases]., Shimizu H,Nakagami H,Morishita R,Nihon rinsho,Japanese journal of clinical medicine, Vol. 70, No. 9, p. 1524-1529, 2012/09
Nucleic Acid Drugs for Preventing Restenosis after Coronary Revascularization, Takashi Miyake,Hironori Nakagami,Ryuichi Morishita, CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 15, p. 1613-1620, 2012/08
Modification of Decoy Oligodeoxynucleotides to Achieve the Stability and Therapeutic Efficacy, Mariana Kiomy Osako,Hironori Nakagami,Ryuichi Morishita, CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 15, p. 1603-1607, 2012/08
Development of Nucleic Acid Drugs for Neurological Disorders, Munehisa Shimamura,Naoyuki Sato,Hironori Nakagami,Yoshiaki Taniyama,Ryuichi Morishita, CURRENT TOPICS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBL LTD, Vol. 12, No. 15, p. 1621-1629, 2012/08
Modification of a novel angiogenic peptide, AG30, for the development of novel therapeutic agents, Hironori Nakagami,Tomoyuki Nishikawa,Nao Tamura,Akito Maeda,Hajime Hibino,Masayoshi Mochizuki,Takashi Shimosato,Toshinori Moriya,Ryuichi Morishita,Katsuto Tamai,Kazunori Tomono,Yasufumi Kaneda, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, WILEY-BLACKWELL, Vol. 16, No. 7, p. 1629-1639, 2012/07
HIG1, a novel regulator of mitochondrial gamma-secretase, maintains normal mitochondrial function, Hiroki Hayashi,Hironori Nakagami,Makiko Takeichi,Munehisa Shimamura,Nobutaka Koibuchi,Eiji Oiki,Naoyuki Sato,Hiroshi Koriyama,Masaki Mori,Rodriguez Gerardo Araujo,Akito Maeda,Ryuichi Morishita,Katsuto Tamai,Yasufumi Kaneda, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 26, No. 6, p. 2306-2317, 2012/06
パーキンソン病関連分子αシヌクレインの老化関連疾患における新規機能メタボリック症候群及び血管内皮機能への関与, 鷹見洋一,大石充,中神啓徳,神出計,山本浩一,金田安史,楽木宏実, 日本高血圧学会臨床高血圧フォーラムプログラム・抄録集, (NPO)日本高血圧学会, Vol. 1回, p. 139-139, 2012/04
Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells, Masaki Mori,Hironori Nakagami,Gerardo Rodriguez-Araujo,Keisuke Nimura,Yasufumi Kaneda, PLOS BIOLOGY, PUBLIC LIBRARY SCIENCE, Vol. 10, No. 4, 2012/04
Role of Central Nervous System Periostin in Cerebral Ischemia, Munehisa Shimamura,Yoshiaki Taniyama,Naruto Katsuragi,Nobutaka Koibuchi,Mariko Kyutoku,Naoyuki Sato,Mohammad Allahtavakoli,Kouji Wakayama,Hironori Nakagami,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 43, No. 4, p. 1108-U341, 2012/04
Development and Modification of Decoy Oligodeoxynucleotides for Clinical Application, Mariana Kiomy Osako,Hironori Nakagami,Ryuichi Morishita, NUCLEIC ACID DRUGS, SPRINGER-VERLAG BERLIN, Vol. 249, p. 49-59, 2012
Links Between Hypertension and Osteoporosis: Benidipine Ameliorates Osteoporosis in Ovariectomized Hypertensive Rats Through Promotion of Osteoblast Proliferation and Inhibition of Osteoclast Differentiation, Shimizu H,Nakagami H,Yasumasa N,Mariana O.K,Kyutoku M,Koriyama H,Nakagami F,Shimamura M,Rakugi H,Morishita R, Current Cardiovascular Risk Reports, SPRINGER, Vol. 6, No. 4, p. 274-280, 2012
Nifedipine prevents hepatic fibrosis in a non-alcoholic steatohepatitis model induced by an L-methionine-and choline-deficient diet, Hironori Nakagami,Munehisa Shimamura,Takashi Miyake,Takashi Shimosato,Noriko Minobe,Toshinori Moritani,Mariana Kiomy Osako,Futoshi Nakagami,Hiroshi Koriyama,Mariko Kyutoku,Hideo Shimizu,Tomohiro Katsuya,Ryuichi Morishita, MOLECULAR MEDICINE REPORTS, SPANDIDOS PUBL LTD, Vol. 5, No. 1, p. 37-40, 2012/01
Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Osako Kiomy Mariana,Mariko Kyutoku,Hiroshi Koriyama,Futoshi Nakagami,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 35, No. 1, p. 77-81, 2012/01
Salt-inducible kinase 1 influences Na(+),K(+)-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure., Popov S,Silveira A,Wågsäter D,Takemori H,Oguro R,Matsumoto S,Sugimoto K,Kamide K,Hirose T,Satoh M,Metoki H,Kikuya M,Ohkubo T,Katsuya T,Rakugi H,Imai Y,Sanchez F,Leosdottir M,Syvänen AC,Hamsten A,Melander O,Bertorello AM, Journal of hypertension, 12, Vol. 29, No. 12, p. 2395-2403, 2011/12
Critical Roles of Cold Shock Domain Protein A as an Endogenous Angiogenesis Inhibitor in Skeletal Muscle, Yukihiro Saito,Hironori Nakagami,Nobuyoshi Azuma,Satoshi Hirata,Fumihiro Sanada,Yoshiaki Taniyama,Ryuichi Morishita,Yasufumi Kaneda,Tadahiro Sasajima, ANTIOXIDANTS & REDOX SIGNALING, MARY ANN LIEBERT INC, Vol. 15, No. 8, p. 2109-2120, 2011/10
Irbesartan improves endothelial dysfunction, abnormal lipid profile, proteinuria and liver dysfunction in Zucker diabetic fatty rats independent of glucose and insulin levels, Munehisa Shimamura,Hironori Nakagami,Takashi Shimosato,Toshinori Moritani,Futoshi Nakagami,Mariana Kiomy Osako,Takashi Miyake,Hiroshi Koriyama,Hideo Shimizu,Ryuichi Morishita, EXPERIMENTAL AND THERAPEUTIC MEDICINE, SPANDIDOS PUBL LTD, Vol. 2, No. 5, p. 957-961, 2011/09
Can Forkhead Box P1 be a novel therapeutic target for atherosclerosis?, Hironori Nakagami,Ryuichi Morishita, ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Vol. 218, No. 1, p. 26-27, 2011/09
[The cutting-edge of medicine; anti-aging and cardiovascular diseases]., Nakagami H,Morishita R,Nihon Naika,Gakkai,zasshi. The Journal of,the,Japanese,Society of Internal,Medicine, Nihon Naika Gakkai Kaishi, The Japanese Society of Internal Medicine, Vol. 100, No. 6, p. 1677-1682, 2011/06
[Hypertension, CKD and bone metabolism]., Nakagami H,Morishita R,Clinical calcium, Vol. 21, No. 5, p. 685-689, 2011/05
低用量の利尿剤とARB併用によるRAS活性の抑制と骨代謝改善効果, 志水秀郎,安政奈都記,島村宗尚,楠博,中神啓徳,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, (一社)日本抗加齢医学会, Vol. 11回, p. 317-317, 2011/04
Association of (pro)renin receptor gene polymorphisms with lacunar infarction and left ventricular hypertrophy in Japanese women: the Ohasama study., Hirose T,Hashimoto M,Totsune K,Metoki H,Hara A,Satoh M,Kikuya M,Ohkubo T,Asayama K,Kondo T,Kamide K,Katsuya T,Ogihara T,Izumi S,Rakugi H,Takahashi K,Imai Y, Hypertension research : official journal of the Japanese Society of Hypertension, 4, Vol. 34, No. 4, p. 530-535, 2011/04
Obesity and Gastrointestinal Hormones-Dual Effect of Angiotensin II Receptor Blockade and a Partial Agonist of PPAR-gamma, Hironori Nakagami,Ryuichi Morishita, CURRENT VASCULAR PHARMACOLOGY, BENTHAM SCIENCE PUBL LTD, Vol. 9, No. 2, p. 162-166, 2011/03
[Common molecular mechanism of osteoporosis and vascular diseases]., Hironori Nakagami,Mariana Kiomy Osako,Hideo Shimizu,Hiromi Rakugi,Ryuichi Morishita, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, Vol. 48, No. 2, p. 146-8, 2011
Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor kappa B and Ets Prevents Abdominal Aortic Aneurysm in Rat Model, Takashi Miyake,Motokuni Aoki,Mariana K. Osako,Munehisa Shimamura,Hironori Nakagami,Ryuichi Morishita, MOLECULAR THERAPY, NATURE PUBLISHING GROUP, Vol. 19, No. 1, p. 181-187, 2011/01
New Concept of Vascular Calcification and Metabolism, Hironori Nakagami,Mariana K. Osako,Ryuichi Morishita, CURRENT VASCULAR PHARMACOLOGY, BENTHAM SCIENCE PUBL LTD, Vol. 9, No. 1, p. 124-127, 2011/01
Cold shock domain protein A (CSDA) overexpression inhibits tumor growth and lymph node metastasis in a mouse model of squamous cell carcinoma, Goichi Matsumoto,Nobuyuki Yajima,Hiroyuki Saito,Hironori Nakagami,Yasushi Omi,Ushaku Lee,Yasufumi Kaneda, CLINICAL & EXPERIMENTAL METASTASIS, SPRINGER, Vol. 27, No. 7, p. 539-547, 2010/10
Prevention and regression of non-alcoholic steatohepatitis (NASH) in a rat model by metabosartan, telmisartan, Hironori Nakagami,Mariana Kiomy Osako,Futoshi Nakagami,Takashi Shimosato,Noriko Minobe,Toshinori Moritani,Munehisa Shimamura,Takashi Miyake,Hideo Shimizu,Yasushi Takeya,Ryuichi Morishita, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS PUBL LTD, Vol. 26, No. 4, p. 477-481, 2010/10
Estrogen Inhibits Vascular Calcification via Vascular RANKL System Common Mechanism of Osteoporosis and Vascular Calcification, Mariana Kiomy Osako,Hironori Nakagami,Nobutaka Koibuchi,Hideo Shimizu,Futoshi Nakagami,Hiroshi Koriyama,Munehisa Shimamura,Takashi Miyake,Hiromi Rakugi,Ryuichi Morishita, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 107, No. 4, p. 466-U57, 2010/08
Inorganic polyphosphate differentiates human mesenchymal stem cells into osteoblastic cells, Daiki Morimoto,Tetsuya Tomita,Shoko Kuroda,Chikahisa Higuchi,Shinichi Kato,Toshikazu Shiba,Hironori Nakagami,Ryuichi Morishita,Hideki Yoshikawa, JOURNAL OF BONE AND MINERAL METABOLISM, SPRINGER TOKYO, Vol. 28, No. 4, p. 418-423, 2010/07
Estrogen attenuates vascular remodeling in Lp(a) transgenic mice, Futoshi Nakagami,Hironori Nakagami,Mariana Kiomy Osako,Masaaki Iwabayashi,Yoshiaki Taniyama,Takefumi Doi,Hideo Shimizu,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Vol. 211, No. 1, p. 41-47, 2010/07
Variation in OSBPL10 is associated with dyslipidemia, Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Hiroshi Akasaka,Shigeyuki Saitoh,Kazuaki Shimamoto,Toshio Ogihara,Yasufumi Kaneda,Ryuichi Morishita,Hiromi Rakugi, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 33, No. 5, p. 511-514, 2010/05
Effect of an Antimicrobial Agent on Atherosclerotic Plaques Assessment of Metalloproteinase Activity by Molecular Imaging, Satoru Ohshima,Shinichiro Fujimoto,Artiom Petrov,Hironori Nakagami,Nezam Haider,Jun Zhou,Nobuhiro Tahara,Mariana Kiomy Osako,Ai Fujimoto,Jie Zhu,Toyoaki Murohara,D. Scott Edwards,Navneet Narula,Nathan D. Wong,Y. Chandrashekhar,Ryuichi Morishita,Jagat Narula, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, Vol. 55, No. 12, p. 1240-1249, 2010/03
Accumulation of common polymorphisms is associated with development of hypertension:a 12-year follow-up from the Ohasama study., Watanabe Y,Metoki H,Ohkubo T,Katsuya T,Tabara Y,Kikuya M,Hirose T,Sugimoto K,Asayama K,Inoue R,Hara A,Obara T,Nakura J,Kohara K,Totsune K,Ogihara T,Rakugi H,Miki T,Imai Y, Hypertension Research, Vol. 33, No. 2, p. 129-134, 2010/02
Gene Therapy Toward Clinical Application in the Cardiovascular Field, Hironori Nakagami,Mariana Kiomy Osako,Ryuichi Morishita, Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging, Oxford University Press, 2010/01/01
Anti-Aging Medicine in Cardiovascular Disease, Morishita Ryuichi,Komuro Issei,Horiuchi Masatsugu,Nakagami Hironori,Minamino Toru,Higashi Yukihito, Anti-Aging Med, Japanese Society of Anti-Aging Medicine, Vol. 7, No. 5, p. 45-49, 2010
Identification of Evidence Suggestive of an Association with Peripheral Arterial Disease at the OSBPL10 Locus by Genome-Wide Investigation in the Japanese Population, Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Ken Sugimoto,Hidetoshi Yamashita,Yoichi Takami,Shiro Maeda,Michiaki Kubo,Atsushi Takahashi,Yusuke Nakamura,Toshio Ogihara,Hiromi Rakugi,Yasufumi Kaneda,Ryuichi Morishita, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, JAPAN ATHEROSCLEROSIS SOC, Vol. 17, No. 10, p. 1054-1062, 2010
Priming With Angiopoietin-1 Augments the Vasculogenic Potential of the Peripheral Blood Stem Cells Mobilized With Granulocyte Colony-Stimulating Factor Through a Novel Tie2/Ets-1 Pathway, Min-Seok Kim,Choon-Soo Lee,Jin Hur,Hyun-Jai Cho,Soo-In Jun,Tae-Youn Kim,Sae-Won Lee,Jung-Won Suh,Kyung-Woo Park,Hae-Young Lee,Hyun-Jae Kang,Dong-Soo Lee,Gou-Young Koh,Hironori Nakagami,Ryuichi Morishita,Young-Bae Park,Hyo-Soo Kim, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 120, No. 22, p. 2240-U150, 2009/12
Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive rats, Hideo Shimizu,Hironori Nakagami,Mariana Kiomy Osako,Futoshi Nakagami,Yasuo Kunugiza,Tetsuya Tomita,Hideki Yoshikawa,Hiromi Rakugi,Toshio Ogihara,Ryuichi Morishita, HYPERTENSION RESEARCH, NATURE PUBLISHING GROUP, Vol. 32, No. 9, p. 786-790, 2009/09
New Treatment of Periodontal Diseases by Using NF-kappa B Decoy Oligodeoxynucleotides via Prevention of Bone Resorption and Promotion of Wound Healing, Hideo Shimizu,Hironori Nakagami,Shosuke Morita,Ikuyo Tsukamoto,Mariana Kiomy Osako,Futoshi Nakagami,Takashi Shimosato,Noriko Minobe,Ryuichi Morishita, ANTIOXIDANTS & REDOX SIGNALING, MARY ANN LIEBERT, INC, Vol. 11, No. 9, p. 2065-2075, 2009/09
[Hormones and osteoporosis update. Effect of angiotensin II on bone metabolism]., Nakagami H,Morishita R,Clinical calcium, Vol. 19, No. 7, p. 997-1002, 2009/07
[Gene therapy for anti-aging medicine]., Nakagami H,Morishita R,Nihon rinsho,Japanese journal of clinical medicine, Vol. 67, No. 7, p. 1407-1411, 2009/07
Zyxin Mediates Actin Fiber Reorganization in Epithelial-Mesenchymal Transition and Contributes to Endocardial Morphogenesis, Masaki Mori,Hironori Nakagami,Nobutaka Koibuchi,Koichi Miura,Yoichi Takami,Hiroshi Koriyama,Hiroki Hayashi,Hisataka Sabe,Naoki Mochizuki,Ryuichi Morishita,Yasufumi Kaneda, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 20, No. 13, p. 3115-3124, 2009/07
FHL-2 Suppresses VEGF-Induced Phosphatidylinositol 3-Kinase/Akt Activation via Interaction With Sphingosine Kinase-1, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Hiroshi Koriyama,Masaki Mori,Katsuto Tamai,Jianxin Sun,Kaori Nagao,Ryuichi Morishita,Yasufumi Kaneda, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 29, No. 6, p. 909-U331, 2009/06
Fluvastatin improves osteoporosis in fructose-fed insulin resistant model rats through blockade of the classical mevalonate pathway and antioxidant action, Rie Hanayam,Hideo Shimizu,Hironori Nakagami,Mariana Kiomy Osako,Hirofumi Makino,Yasuo Kunugiza,Tetsuya Tomita,Ikuyo Tsukamoto,Hideki Yoshikawa,Hiromi Rakugi,Ryuchi Morishita, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS PUBL LTD, Vol. 23, No. 5, p. 581-588, 2009/05
Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study., Hirose T,Hashimoto M,Totsune K,Metoki H,Asayama K,Kikuya M,Sugimoto K,Katsuya T,Ohkubo T,Hashimoto J,Rakugi H,Takahashi K,Imai Y, American journal of hypertension, 3, Vol. 22, p. 294-299, 2009/03
Vascular protective effects of ezetimibe in ApoE-deficient mice, Hironori Nakagami,Mariana Kiomy Osako,Yoichi Takami,Rie Hanayama,Hiroshi Koriyama,Masaki Mori,Hiroki Hayashi,Hideo Shimizu,Ryuichi Morishita, ATHEROSCLEROSIS, ELSEVIER IRELAND LTD, Vol. 203, No. 1, p. 51-58, 2009/03
Development of a novel antimicrobial peptide, AG-30, with angiogenic properties, Tomoyuki Nishikawa,Hironori Nakagami,Akito Maeda,Ryuichi Morishita,Nobuhiko Miyazaki,Toshihiro Ogawa,Yasuhiko Tabata,Yasushi Kikuchi,Hiroki Hayashi,Yoshiro Tatsu,Noboru Yumoto,Katsuto Tamai,Kazunori Tomono,Yasufumi Kaneda, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, WILEY-BLACKWELL PUBLISHING, INC, Vol. 13, No. 3, p. 535-546, 2009/03
PITAVASTATIN SUPPRESSES FORMATION AND PROGRESSION OF CEREBRAL ANEURYSMS THROUGH INHIBITION OF THE NUCLEAR FACTOR kappa B PATHWAY, Tomohiro Aoki,Hiroharu Kataoka,Ryota Ishibashi,Hironori Nakagami,Kazuhiko Nozaki,Ryuuichi Morishita,Nobuo Hashimoto, NEUROSURGERY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 64, No. 2, p. 357-365, 2009/02
ゲノムワイド関連解析による閉塞性動脈硬化症感受性遺伝子座の同定, 郡山弘,中神啓徳,勝谷友宏,杉本研,山下英俊,鷹見洋一,赤坂憲,斎藤重幸,前田士朗,中村裕輔,金田安史,樂木宏実,森下竜一,島本和明,荻原俊男, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 31回, p. 170-170, 2008/10
テルミサルタンの抗動脈硬化作用の検討, 中神啓徳,鷹見洋一,郡山弘,勝谷友宏,樂木宏実,森下竜一, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 31回, p. 175-175, 2008/10
Cold shock domain protein A, novel endogenous regulator of angiogenesis in heart, Yukihiro Saito,Hironori Nakagami,Nobuyoshi Azuma,Ryuichi Morishita,Yasufumi Kaneda,Tadahiro Sasajima, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 45, No. 4, p. S7-S8, 2008/10
Differential response of vascular hepatocyte growth factor concentration and lipid accumulation between telmisartan and losartan in ApoE-deficient mice, Hironori Nakagami,Mariana Kiomy Osako,Yoichi Takami,Rie Hanayama,Hiroshi Koriyama,Masaki Mori,Hiroki Hayashi,Hideo Shimizu,Ryuichi Morishita, MOLECULAR MEDICINE REPORTS, SPANDIDOS PUBL LTD, Vol. 1, No. 5, p. 657-661, 2008/09
Angiotensin II accelerates osteoporosis by activating osteoclasts, Hideo Shimizu,Hironori Nakagami,Mariana Kiomy Osako,Rie Hanayama,Yasuo Kunugiza,Takuji Kizawa,Tetsuya Tomita,Hideki Yoshikawa,Toshio Ogihara,Ryuichi Morishita, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 22, No. 7, p. 2465-2475, 2008/07
Pleiotropic effect of statins as antioxidants on cardiac hypertrophy, Hironori Nakagami,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 8, No. 2, p. 167-171, 2008/06
Identification of angiogenic and antimicrobial factor, AG-30, and analysis of its De Novo engineered variants, Tomoyuki Nishikawa,Hironori Nakagami,Akito Maeda,Nobuhiko Miyazaki,Yasuhiko Tabata,Ryuichi Morishita,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 10, No. 4, p. 473-473, 2008/04
Potential role of CYLD (cylindromatosis) as a deubiquitinating enzyme in vascular cells, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Hiroki Hayashi,Masaki Mori,Hiroshi Koriyama,Yoshichika Baba,Osamu Yasuda,Hiromi Rakugi,Toshio Ogihara,Yasufumi Kaneda, AMERICAN JOURNAL OF PATHOLOGY, AMER SOC INVESTIGATIVE PATHOLOGY, INC, Vol. 172, No. 3, p. 818-829, 2008/03
Cold shock domain protein A represses angiogenesis and lymphangiogenesis via inhibition of serum response element, Y. Saito,H. Nakagami,M. Kurooka,Y. Takami,Y. Kikuchi,H. Hayashi,T. Nishikawa,K. Tamai,R. Morishita,N. Azuma,T. Sasajima,Y. Kaneda, ONCOGENE, NATURE PUBLISHING GROUP, Vol. 27, No. 13, p. 1821-1833, 2008/03
Polymorphism of myospryn is associated with left ventricular diastolic dysfunction, Kikuchi Yasushi,Nakagami Hironori,Katsuya Tomohiro,Morishita Ryuichi,Horio Takeshi,Kamide Kei,Miyata Toshiyuki,Kawano Yuhei,Takami Yoichi,Rakugi Hiromi,Kaneda Yasufumi,Ogihara Toshio, Anti-Aging Med, Japanese Society of Anti-Aging Medicine, Vol. 5, No. 4, p. 49-52, 2008
Aging of Blood Vessels, Nakagami Hironori,Morishita Ryuichi, Anti-Aging Med, Japanese Society of Anti-Aging Medicine, Vol. 5, No. 7, p. 73-77, 2008
NFκB decoy oligodeoxynucleotide-based therapy in cardiovascular diseases, H. Nakagami,M. K. Osako,N. Tomita,R. Morishita, RNA Technologies in Cardiovascular Medicine and Research, Springer-Verlag Berlin Heidelberg, p. 299-309, 2008
NF-kappa B is a key mediator of cerebral aneurysm formation, Tomohiro Aoki,Hiroharu Kataoka,Munehisa Shimamura,Hironori Nakagami,Kouji Wakayama,Takuya Moriwaki,Ryota Ishibashi,Kazuhiko Nozaki,Ryuichi Morishita,Nobuo Hashimoto, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 116, No. 24, p. 2830-2840, 2007/12
Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension, Hironori Nakagami,Yasushi Kikuchi,Tomohiro Katsuya,Ryuichi Morishita,Hiroshi Akasaka,Shigeyuki Saitoh,Hiromi Rakugi,Yasufumi Kaneda,Kazuaki Shimamoto,Toshio Ogihara, HYPERTENSION RESEARCH, JAPANESE SOC HYPERTENSION CENT ACADEMIC SOC, PUBL OFFICE, Vol. 30, No. 12, p. 1239-1246, 2007/12
Involvement of gamma-secretase in postnatal angiogenesis, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Naoyuki Sato,Yukihiro Saito,Tomoyuki Nishikawa,Masaki Mori,Hiroshi Koriyama,Katsuto Tamai,Ryuichi Morishita,Yasufumi Kaneda, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 363, No. 3, p. 584-590, 2007/11
脱ユビキチン化酵素CYLD(cylindromatosis)の血管における機能, 鷹見洋一,中神啓徳,森下竜一,勝谷友宏,楽木宏実,金田安史,荻原俊男, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 30回, p. 160-160, 2007/10
Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappa B activation, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Tai-Xing Cui,Tomonaga Ichikawa,Yukihiro Saito,Hiroki Hayashi,Yasushi Kikuchi,Tomoyuki Nishikawa,Yoshichika Baba,Osamu Yasuda,Hiromi Rakugi,Toshio Ogihara,Yasufumi Kaneda, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 27, No. 10, p. 2184-2190, 2007/10
Recent progress in therapeutic angiogenesis., Nakagami H,Morishita R,International journal of,biomedical science,IJBS, v, Vol. 3, No. 3, p. 153-158, 2007/09
Increase in nuclease resistance and incorporation of NF-kappa B decoy oligodeoxynucteotides by modification of the 3 '-terminus, Mariana Kiomy Osako,Naruya Abstract Tomita,Hironori Nakagami,Yasuo Kunugiza,Masafumi Yoshino,Kazuhiko Yuyama,Tetsuya Tomita,Hideki Be Specific To The Target Transcription Fac,Toshio Ogihara,Ryuichi Morishita, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 9, No. 9, p. 812-819, 2007/09
Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis, Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Yoichi Takami,Yasushi Kikuchi,Hiroki Hayashi,Tomoyuki Nishikawa,Katsuto Tamai,Nobuyoshi Azuma,Tadahiro Sasajima,Yasufumi Kaneda, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 114, No. 11, p. 1177-1184, 2006/09
Novel drug delivery system by surface modified magnetic nanoparticles, Shin-ichi Takeda,Bungo Terazono,Fumihito Mishima,Hironori Nakagami,Shigehiro Nishijima,Yasufumi Kaneda, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, AMER SCIENTIFIC PUBLISHERS, Vol. 6, No. 9-10, p. 3269-3276, 2006/09
[Endothelial cell growth inhibitory gene]., Nakagami H,Kaneda T,Nihon rinsho,Japanese journal of clinical medicine,Suppl, Vol. 64 Suppl 5, p. 428-431, 2006/07
Model of vasculogenesis from embryonic stem cells for vascular research and regenerative medicine, Hironori Nakagami,Namika Nakagawa,Yasushi Takeya,Katsunobu Kashiwagi,Chisato Ishida,Shin-ichiro Hayashi,Motokuni Aoki,Kunio Matsumoto,Toshikazu Nakamura,Toshio Ogihara,Ryuichi Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 1, p. 112-119, 2006/07
NF kappa B decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts, H Shimizu,H Nakagami,Tsukamoto, I,S Morita,Y Kunugiza,T Tomita,H Yoshikawa,Y Kaneda,T Ogihara,R Morishita, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 13, No. 12, p. 933-941, 2006/06
Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4, F Xiang,Y Sakata,L Cui,JM Youngblood,H Nakagami,JK Liao,RL Liao,MT Chin, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, Vol. 290, No. 5, p. H1997-H2006, 2006/05
Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector, T Nishikawa,H Nakagami,A Matsuki,A Maeda,CY Yo,T Harada,R Morishita,K Tamai,Y Kaneda, HUMAN GENE THERAPY, MARY ANN LIEBERT INC, Vol. 17, No. 4, p. 470-475, 2006/04
Anti-oxidant gene therapy by NF kappa B decoy oligodeoxynucleotide, Hironori Nakagami,Naruya Tomita,Yasufumi Kaneda,Toshio Ogihara,Ryuichi Morishita, CURRENT PHARMACEUTICAL BIOTECHNOLOGY, BENTHAM SCIENCE PUBL LTD, Vol. 7, No. 2, p. 95-100, 2006/04
Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy, H Nakagami,R Morishita,K Maeda,Y Kikuchi,T Ogihara,Y Kaneda, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, JAPAN ATHEROSCLEROSIS SOC, Vol. 13, No. 2, p. 77-81, 2006/04
Application of NFkB decoy oligonucleotides to bone metabolic diseases - in vitro and in vivo studies, H. Shimizu,H. Nakagami,S. Morita,N. Yasumasa,R. Hanayama,T. Ogihara,R. Morishita, PROCEEDINGS OF THE XVIII CONGRESS OF THE EUROPEAN ASSOCIATION FOR CRANIO-MAXILLO FACIAL SURGERY, MEDIMOND S R L, p. 165-+, 2006
Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells, H Nakagami,K Maeda,R Morishita,S Iguchi,T Nishikawa,Y Takami,Y Kikuchi,Y Saito,K Tamai,T Ogihara,Y Kaneda, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 25, No. 12, p. 2542-2547, 2005/12
HVJ-Eベクターを用いたHigh Throughput Screeningによる新規遺伝子機能スクリーニング血管リモデリング抑制遺伝子の検索, 鷹見洋一,中神啓徳,勝谷友宏,楽木宏実,森下竜一,金田安史,荻原俊男, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 28回, p. 84-84, 2005/09
Hepatocyte growth factor(HGF)によるリンパ管新生作用, 斉藤幸裕,中神啓徳,鷹見洋一,森下竜一,金田安史,東信良,笹嶋唯博, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 28回, p. 87-87, 2005/09
Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector, N Morishita,H Nakagami,R Morishita,S Takeda,F Mishima,B Terazono,S Nishijima,Y Kaneda,N Tanaka, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 334, No. 4, p. 1121-1126, 2005/09
Hepatocyte growth factor as potential cardiovascular therapy, Hironori Nakagami,Yasufumi Kaneda,Toshio Ogihara,Ryuichi Morishita, Expert Review of Cardiovascular Therapy, TAYLOR & FRANCIS INC, Vol. 3, No. 3, p. 513-519, 2005/05
Fundamental Study on Gene Therapy Utilizing Ferromagnetic Nanoparticles, Yoko Akiyama,Bungo Terazono,Fumihito Mishima,Shin-ichi Takeda,Yoshinobu Izumi,Kimiko Ema,Hironori Nakagami,Yasushi Kaneda,Shigehiro Nishijima, Abstract Book of 3rd International Symposium of 21stCentury COE "Towards Creating New Industries Based on Inter-Nanoscience"2005,p.107-108., 2005/03
Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis., Nakagami H,Kaneda Y,Ogihara T,Morishita R,Current diabetes reviews, CURRENT DIABETES REVIEWS, BENTHAM SCIENCE PUBL LTD, Vol. 1, No. 1, p. 59-63, 2005/02
Hypoxia-induced renal epithelial cell death through caspase-dependent pathway: Role of Bcl-2, Bcl-xL and Bax in tubular injury, K Yamamoto,N Tomita,S Yoshimura,H Nakagami,Y Taniyama,K Yamasaki,T Ogihara,R Morishita, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS PUBL LTD, Vol. 14, No. 4, p. 633-640, 2004/10
Statins and myocardial hypertrophy, H Nakagami,JK Liao, CORONARY ARTERY DISEASE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 15, No. 5, p. 247-250, 2004/08
Pharmacogenomics and Translational Research, NAKAGAMI Hironori, Jpn. J. Clin. Pharmacol. Ther., The Japanese Society of Clinical Pharmacology and Therapeutics, Vol. 35, No. 3, p. 124-128, 2004/05/31
Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells, H Nakagami,R Morishita,T Nishikawa,H Shimizu,S Iguchi,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, HYPERTENSION RESEARCH, JAPANESE SOC HYPERTENSION CENT ACADEMIC SOC, PUBL OFFICE, Vol. 27, No. 5, p. 359-365, 2004/05
No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice, A Matsuki,S Yamamoto,H Nakagami,M Aoki,K Tamai,K Matsumoto,T Nakamura,T Ogihara,Y Kaneda,R Morishita, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 315, No. 1, p. 59-65, 2004/02
NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy, H Nakagami,M Takemoto,JK Liao, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 35, No. 7, p. 851-859, 2003/07
A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterol-independent mechanisms, H Nakagami,KS Jensen,JK Liao, ANNALS OF MEDICINE, ROYAL SOC MEDICINE PRESS LTD, Vol. 35, No. 6, p. 398-403, 2003
HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model, M Nakabayashi,R Morishita,H Nakagami,K Kuba,K Matsumoto,T Nakamura,Y Tano,Y Kaneda, DIABETOLOGIA, SPRINGER-VERLAG, Vol. 46, No. 1, p. 115-123, 2003/01
Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation, M Horiuchi,TX Cui,Z Li,JM Li,H Nakagami,M Iwai, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 107, No. 1, p. 106-112, 2003/01
Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2, Y Sakata,CN Kamei,H Nakagami,R Bronson,JK Liao,MT Chin, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 99, No. 25, p. 16197-16202, 2002/12
Angiotensin II subtype 2 receptor activation inhibits insulin-induced phosphoinositide 3-kinase and Akt and induces apoptosis in PC12W cells, TX Cui,H Nakagami,C Nahmias,T Shiuchi,Y Takeda-Matsubara,JM Li,L Wu,M Iwai,M Horiuchi, MOLECULAR ENDOCRINOLOGY, ENDOCRINE SOC, Vol. 16, No. 9, p. 2113-2123, 2002/09
ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO, T Shiuchi,TX Cui,L Wu,H Nakagami,Y Takeda-Matsubara,M Iwai,M Horiuchi, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 40, No. 3, p. 329-334, 2002/09
Role of angiotensin II-regulated apoptosis through distinct AT(1) and AT(2) receptors in neointimal formation, J Suzuki,M Iwai,H Nakagami,L Wu,R Chen,T Sugaya,M Hamada,K Hiwada,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 7, p. 847-853, 2002/08
Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,K Yamasaki,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, DIABETES, AMER DIABETES ASSOC, Vol. 51, No. 8, p. 2604-2611, 2002/08
N141I mutant Presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression, M Mori,H Nakagami,R Morishita,N Mitsuda,K Yamamoto,S Yoshimura,N Ohkubo,N Sato,T Ogihara,Y Kaneda, LIFE SCIENCES, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 70, No. 21, p. 2567-2580, 2002/04
Tumor necrosis factor-alpha inhibits growth factor-mediated cell proliferation through SHP-1 activation in endothelial cells, H Nakagami,TX Cui,M Iwai,T Shiuchi,Y Takeda-Matsubara,L Wu,M Horiuchi, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 22, No. 2, p. 238-242, 2002/02
Estrogen activates phosphatases and antagonizes growth-promoting effect of angiotensin II, Y Takeda-Matsubara,H Nakagami,M Iwai,TX Cui,T Shiuchi,M Akishita,C Nahmias,M Ito,M Horiuchi, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, No. 1, p. 41-45, 2002/01
Effect of angiotensin II type 1 receptor blockade on cardiac remodeling in angiotensin II type 2 receptor null mice, L Wu,M Iwai,H Nakagami,R Chen,J Suzuki,M Akishita,M de Gasparo,M Horiuchi, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 22, No. 1, p. 49-54, 2002/01
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model - Molecular mechanisms of delayed angiogenesis in diabetes, Y Taniyama,R Morishita,K Hiraoka,M Aoki,H Nakagami,K Yamasaki,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 19, p. 2344-2350, 2001/11
Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy, M Takemoto,K Node,H Nakagami,YL Liao,M Grimm,Y Takemoto,M Kitakaze,JK Liao, JOURNAL OF CLINICAL INVESTIGATION, AMER SOC CLINICAL INVESTIGATION INC, Vol. 108, No. 10, p. 1429-1437, 2001/11
Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury, L Wu,M Iwai,H Nakagami,Z Li,R Chen,J Suzuki,M Akishita,M de Gasparo,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 22, p. 2716-2721, 2001/11
Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element "decoy' of nuclear factor-kB binding site as a novel molecular strategy, S Yoshimura,R Morishita,K Hayashi,K Yamamoto,H Nakagami,Y Kaneda,N Sakai,T Ogihara, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 8, No. 21, p. 1635-1642, 2001/11
Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons, K Hayashi,R Morishita,H Nakagami,S Yoshimura,A Hara,K Matsumoto,T Nakamura,T Ogihara,Y Kaneda,N Sakai, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 8, No. 15, p. 1167-1173, 2001/08
Endothelial apoptosis induced by oxidative stress through activation of NF-kappa B - Antiapoptotic effect of antioxidant agents on endothelial cells, M Aoki,T Nata,R Morishita,H Matsushita,H Nakagami,K Yamamoto,K Yamazaki,M Nakabayashi,T Ogihara,Y Kaneda, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 38, No. 1, p. 48-55, 2001/07
Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells, H Nakagami,R Morishita,K Yamamoto,S Yoshimura,Y Taniyama,M Aoki,H Matsubara,S Kim,Y Kaneda,T Ogihara, DIABETES, AMER DIABETES ASSOC, Vol. 50, No. 6, p. 1472-1481, 2001/06
Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells, K Yamamoto,R Morishita,S Hayashi,H Matsushita,H Nakagami,A Moriguchi,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 37, No. 5, p. 1341-1348, 2001/05
Pivotal role of tyrosine phosphatase SHP-1 in AT2 receptor-mediated apoptosis in rat fetal vascular smooth muscle cell, TX Cui,H Nakagami,M Iwai,Y Takeda,T Shiuchi,L Daviet,C Nahmias,M Horiuchi, CARDIOVASCULAR RESEARCH, ELSEVIER SCIENCE BV, Vol. 49, No. 4, p. 863-871, 2001/03
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease, Y Taniyama,R Morishita,M Aoki,H Nakagami,K Yamamoto,K Yamazaki,K Matsumoto,T Nakamura,Y Kaneda,T Ogihara, GENE THERAPY, NATURE PUBLISHING GROUP, Vol. 8, No. 3, p. 181-189, 2001/02
Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and Akt in endothelial cells, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,K Matsumoto,T Nakamura,Y Kaneda,M Horiuchi,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 37, No. 2, p. 581-586, 2001/02
Involvement of bradykinin and nitric oxide in leptin-mediated glucose uptake in skeletal muscle, T Shiuchi,H Nakagami,M Iwai,Y Takeda,TX Cui,R Chen,Y Minokoshi,M Horiuchi, ENDOCRINOLOGY, ENDOCRINE SOC, Vol. 142, No. 2, p. 608-612, 2001/02
ATRAP, novel AT1 receptor associated protein, enhances internalization of AT1 receptor and inhibits vascular smooth muscle cell growth, TX Cui,H Nakagami,M Iwai,Y Takeda,T Shiuchi,K Tamura,L Daviet,M Horiuchi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 279, No. 3, p. 938-941, 2000/12
Anti-apoptotic action of hepatocyte growth factor through mitogen-activated protein kinase on human aortic endothelial cells, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,S Kim,K Matsumoto,T Nakamura,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, No. 10, p. 1411-1420, 2000/10
Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model - Potential application of ribozyme strategy to treat cardiovascular disease, K Yamamoto,R Morishita,N Tomita,T Shimozato,H Nakagami,A Kikuchi,M Aoki,J Higaki,Y Kaneda,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 11, p. 1308-1314, 2000/09
Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters, Y Taniyama,R Morishita,H Nakagami,A Moriguchi,H Sakonjo,Shokei-Kim,K Matsumoto,T Nakamura,J Higaki,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 2, p. 246-+, 2000/07
Hypoxia-induced endothelial apoptosis through nuclear factor-kappa B (NF-kappa B)-mediated bcl-2 suppression - In vivo evidence of the importance of NF-kappa B in endothelial cell regulation, H Matsushita,R Morishita,T Nata,M Aoki,H Nakagami,Y Taniyama,K Yamamoto,J Higaki,K Yasufumi,T Ogihara, CIRCULATION RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, Vol. 86, No. 9, p. 974-981, 2000/05
Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells, H Matsushita,R Morishita,M Aoki,N Tomita,Y Taniyama,H Nakagami,T Shimozato,J Higaki,Y Kaneda,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 101, No. 12, p. 1447-1452, 2000/03
Contribution of cardiovascular hypersensitivity to orthostatic hypertension and the extreme dipper phenomenon, A Moriguchi,H Nakagami,N Kotani,J Higaki,T Ogihara, HYPERTENSION RESEARCH, JAPANESE SOC HYPERTENSION CENT ACADEMIC SOC, PUBL OFFICE, Vol. 23, No. 2, p. 119-123, 2000/03
Gene therapy for myocardial infarction: A real medicine in the next millenium?, R Morishita,M Aoki,H Nakagami,Y Taniyama,K Yamamoto,H Matsushita,K Matsumoto,J Higaki,Y Kaneda,T Ogihara, HEART FAILURE, SPRINGER-VERLAG TOKYO, p. 219-226, 2000
Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21, S Hayashi,R Morishita,H Matsushita,H Nakagami,Y Taniyama,T Nakamura,M Aoki,K Yamamoto,J Higaki,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 35, No. 1, p. 237-243, 2000/01
Isolation and characterization of the E2F-like gene in plants, M Sekine,M Ito,K Uemukai,Y Maeda,H Nakagami,A Shinmyo, FEBS LETTERS, ELSEVIER SCIENCE BV, Vol. 460, No. 1, p. 117-122, 1999/10
Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms, H Nakagami,U Ikeda,Y Maeda,K Yamamoto,Y Hojo,K Kario,S Kuroki,K Shimada, JOURNAL OF THROMBOSIS AND THROMBOLYSIS, KLUWER ACADEMIC PUBL, Vol. 8, No. 3, p. 191-195, 1999/10
Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells - Potential role of p53 in regulation of vascular smooth muscle cell growth, M Aoki,R Morishita,H Matsushita,S Hayashi,H Nakagami,K Yamamoto,A Moriguchi,Y Kaneda,J Higaki,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 34, No. 2, p. 192-200, 1999/08
Relative localization of angiotensin-converting enzyme, chymase and angiotensin II in human coronary atherosclerotic lesions, OHISHI M,UEDA M,RAKUGI H,NARUKO T,KOJIMA A,OKAMURA A,HIGAKI J,OGIHARA T, Journal of Hypertension, Vol. 17, No. 4, p. 547-553, 1999
血管内皮細胞における肝細胞増殖因子(HGF)の役割, 中神啓徳,森下竜一,林真一郎,松下英嗣,山本圭,冨田奈留也,守口篤,檜垣実男,荻原俊男, 動脈硬化, (一社)日本動脈硬化学会, Vol. 26, No. Suppl.1, p. 139-139, 1998/11
Recurrent arterial thrombotic disease on young onset and protein S deficiency, H Nakagami,K Kario,T Mitsuhashi,H Fujikawa,U Ikeda,K Shimada, BLOOD COAGULATION & FIBRINOLYSIS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 9, No. 7, p. 667-668, 1998/10
Mitral regurgitation reduces the risk of stroke in patients with nonrheumatic atrial fibrillation, H Nakagami,K Yamamoto,U Ikeda,T Mitsuhashi,T Goto,K Shimada, AMERICAN HEART JOURNAL, MOSBY-YEAR BOOK INC, Vol. 136, No. 3, p. 528-532, 1998/09
Oligonucleotide-based gene therapy for cardiovascular disease, R Morishita,H Nakagami,Y Taniyama,H Matsushita,K Yamamoto,N Tomita,A Moriguchi,K Matsumoto,J Higaki,T Ogihara, CLINICAL CHEMISTRY AND LABORATORY MEDICINE, WALTER DE GRUYTER & CO, Vol. 36, No. 8, p. 529-534, 1998/08
Angiotensin converting enzyme gene polymorphism in essential hypertension based on ambulatory blood pressure monitoring, Y Maeda,U Ikeda,H Ebata,Y Hojo,Y Seino,H Nakagami,K Shimada, AMERICAN JOURNAL OF HYPERTENSION, ELSEVIER SCIENCE INC, Vol. 10, No. 7, p. 786-789, 1997/07
Diurnal blood pressure rhythm in hypertensives with parental history of stroke, Y Maeda,U Ikeda,H Ebata,Y Hojo,H Nakagami,K Shimada, AMERICAN JOURNAL OF HYPERTENSION, ELSEVIER SCIENCE INC, Vol. 10, No. 5, p. 562-564, 1997/05
Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans, OHISHI M,UEDA M,RAKUGI H,NARUKO T,KOJIMA A,OKAMURA A,HIGAKI J,OGIHARA T, Journal of Hypertension, Vol. 15, No. 11, p. 1295-1302, 1997

Misc.

Development of vaccine for SARS-CoV-2., 中神啓徳,森下竜一, 月刊老年内科, Vol. 3, No. 1, 2021
Development of DNA vaccine for SARS-CoV-2., 中神啓徳,森下竜一, 循環器内科, Vol. 89, No. 2, 2021
Peptide Binding Prediction and Visualization of Predicted Residue Pairs Using BERT Based on a Large Scale Protein Database, 玉木竜二,農見俊明,坂口誠,佐藤尭彰,天満昭子,井上誠一,中神啓徳,貞光九月, 人工知能学会全国大会(Web), Vol. 35th, 2021
COVID-19と老年医学 7.COVID-19のワクチン療法, 中神啓徳,森下竜一, Geriatric Medicine, Vol. 59, No. 5, 2021
新規治療としてのワクチン開発, 中神啓徳, 日本高血圧学会臨床高血圧フォーラムプログラム・抄録集(CD-ROM), Vol. 9th, 2021
レビー小体型認知症におけるαシヌクレインオリゴマーの血管内皮に対する作用の病態生理的意義について, 鷹見洋一,王誠,山本浩一,中嶋恒男,竹屋泰,武田朱公,中神啓徳,樂木宏美, 日本老年医学会雑誌, Vol. 58, 2021
Development of anti-thrombotic and hypertensive vaccine for prevention of ischemic stroke, 島村宗尚,中神啓徳, 日本血栓止血学会誌, Vol. 32, No. 3, 2021
老化細胞除去治療の実用化に向けて, 中神啓徳,森下竜一,樂木宏実, 日本老年医学会雑誌, Vol. 58, 2021
ウェルナー症候群の診療ガイドライン 2020, 竹本稔,塚本和久,森聖二郎,窪田吉孝,中神啓徳,茂木精一郎,葛谷雅文,谷口晃,谷口俊文,横手幸太郎, 日本老年医学会雑誌, Vol. 58, 2021
老化T細胞を標的とした細胞除去ワクチンの開発, 中神啓徳, 日本老年医学会雑誌, Vol. 58, 2021
新型コロナウイルスに対するワクチン開発, 中神啓徳,林宏樹,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, Vol. 21st, 2021
マウス内臓脂肪組織中の老化T細胞を標的とした抗老化ワクチンの開発, 吉田翔太,吉田翔太,中神啓徳, 日本抗加齢医学会総会プログラム・抄録集, Vol. 21st, 2021
部分再開通における脳梗塞の病態解析, 島村宗尚,中神啓徳,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, Vol. 21st, 2021
プロダクティブ・エイジングの実現-NMN(ニコチンアミドモノヌクレオチド)への期待-, 中神啓徳, 日本抗加齢医学会総会プログラム・抄録集, Vol. 21st, 2021
新型コロナウイルスに対するワクチン開発, 中神啓徳, 日本抗加齢医学会総会プログラム・抄録集, Vol. 21st, 2021
フレイル関連疾患に対するNMN(ニコチンアミドモノヌクレオチド)への期待, 中神啓徳,赤坂憲,楽木宏実, 日本サルコペニア・フレイル学会誌, Vol. 5, No. Supplement, 2021
Prometheus Bio社イムノクロマト法を用いたCOVID-19診断精度の検討, 藤川龍弥,眞田文博,中神啓徳,森下竜一, Pharma Medica, Vol. 39, No. 7, 2021
プラスミドDNAを用いた遺伝子治療, 中神啓徳, 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), Vol. 53rd, 2021
ポストコロナ時代の次世代バイオロジクスとしてのワクチン開発, 中神啓徳, 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), Vol. 53rd, 2021
加齢性血管内皮障害におけるαシヌクレイン(SNCA)の病態生理機能, 鷹見洋一,王誠,中神啓徳,山本浩一,武田朱公,竹屋泰,金田安史,樂木宏実, 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), Vol. 53rd, 2021
老化細胞制御による探索的治療への挑戦, 中神啓徳, 日本抗加齢医学会総会プログラム・抄録集, Vol. 21st, 2021
Science of plasmid DNA vector technology, 中神啓徳, 医学のあゆみ, Vol. 279, No. 10, 2021
新型コロナウイルス感染症理解と対策の現状ワクチン開発, 中神啓徳,森下竜一, 診断と治療, Vol. 109, No. 11, 2021
今,活性化している高血圧の診療と研究, 苅尾七臣,苅尾七臣,大屋祐輔,大屋祐輔,崎間敦,崎間敦,中神啓徳,中神啓徳,下澤達雄,下澤達雄,楽木宏実,楽木宏実, Therapeutic Research, Vol. 42, No. 12, 2021
新型コロナウイルスをターゲットとしたDNAワクチンの開発, 林宏樹,孫嬌,柳田結花,大寺量子,塩田達夫,小野慎子,松浦善治,蝶野英人,峰野純一,島村宗尚,森下竜一,楽木宏美,中神啓徳, 日本ワクチン学会学術集会プログラム・抄録集, Vol. 25th, 2021
Vaccine development, 中神啓徳,森下竜一, アンチ・エイジング医学, Vol. 16, No. 3, 2020
Development of therapeutic vaccine for high blood pressure, 中神啓徳, 日本臨床, Vol. 78, No. 2, 2020
Toxic effects of α-synuclein oligomers on endothelium involved in DLB pathology, 王誠,鷹見洋一,山本浩一,中嶋恒男,武田朱公,竹屋泰,中神啓徳,樂木宏実, Dementia Japan, Vol. 34, No. 4, 2020
Angiotensin II vaccineによるラットを用いた腹部大動脈瘤増大抑制効果の検討, 倉敷朋弘,三宅隆,中村嘉伸,岸本祐一郎,大野原岳史,掘江弘夢,中神啓徳,森下竜一,西村元延, 日本外科学会定期学術集会(Web), Vol. 120th, 2020
Prediction of peptide binding using BERT based on a large scale protein database, 玉木竜二,農見俊明,佐藤尭彰,井上誠一,貞光九月,坂口誠,天満昭子,中神啓徳, 情報処理学会研究報告(Web), Vol. 2020, No. BIO-64, 2020
住宅環境による血圧変動に関する探索研究, 中神啓徳,勝谷友宏, 日本未病学会学術総会抄録集, Vol. 27th, 2020
早老症の医療水準やQOL向上を目指す集学的研究 Werner症候群の患者・家族支援のためのリーフレット作成, 葛谷雅文,竹本稔,窪田吉孝,茂木精一郎,谷口俊文,忍足俊幸,中神啓徳,谷口晃, 早老症の医療水準やQOL向上を目指す集学的研究令和元年度総括・分担研究報告書(Web), 2020
高断熱・高気密モデルハウスでの血圧変動の観察研究, 中神啓徳,山田秀和,岩前篤,大塚弘樹,秋山均, 日本抗加齢医学会総会プログラム・抄録集, Vol. 20th, 2020
RANKL部分ペプチドMHP1による乾癬に対する治療効果についての検討, 島村宗尚,島村宗尚,鞠楠,林宏樹,中神啓徳,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, Vol. 20th, 2020
Development of therapeutic vaccine for chronic diseases, utilizing of novel gene delivery device, 中神啓徳, 日本薬学会年会要旨集(CD-ROM), Vol. 140th, 2020
炎症制御をターゲットにした脳梗塞急性期治療薬開発の現状と展望, 島村宗尚,中神啓徳,佐々木勉,森下竜一,望月秀樹, 臨床神経学, Vol. 60, p. 253-259, 2020
高血圧に対するワクチン療法, 中神啓徳,森下竜一, 循環器内科, Vol. 85, No. 6, 2019
S100A9を標的とした抗血小板機能ワクチンの開発, 中神啓徳,林宏樹,河野友裕,河野友裕,島村宗尚,島村宗尚, 日本NO学会学術集会プログラム抄録集, Vol. 19th, 2019
注意機構付きLSTMを用いた抗原タンパク質のエピトープ領域予測, 農見俊明,農見俊明,藤田春佳,貞光九月,坂口誠,天満昭子,中神啓徳, 情報処理学会研究報告(Web), Vol. 2019, No. BIO-60, 2019
脂肪分化及び肥満形成におけるMyoferlinの新規機能解明, 野里陽一,鷹見洋一,山本浩一,中神啓徳,華山力成,楽木宏実, 日本高血圧学会総会プログラム・抄録集(CD-ROM), Vol. 42nd, 2019
アンギオテンシンIIワクチンによる血管性認知症の治療効果検討, 島村宗尚,島村宗尚,若山幸示,中神啓徳,森下竜一, Anti-Aging Science, Vol. 11, No. 1, 2019
肥満病態におけるMyoferlinの機能解明, 野里陽一,鷹見洋一,山本浩一,野里聡子,中神啓徳,華山力成,楽木宏実, 日本心血管内分泌代謝学会学術総会プログラム及び抄録集, Vol. 23rd, 2019
生活習慣病を標的とした抗体誘導型ワクチンのトランスレーショナルリサーチ, 中神啓徳, 日本循環制御医学会総会・学術集会プログラム・抄録集, Vol. 40th, 2019
Vaccination Therapy against Semaphorin 3E Ameliorates Glucose Intolerance in Diet-induced Obese Mice(和訳中), 氏家葵,清水逸平,吉田陽子,中神啓徳,南野徹, 日本循環器学会学術集会抄録集, (一社)日本循環器学会, Vol. 82回, p. PJ070-5, 2018/03
Therapeutic Vaccines for Hypertension: a New Option for Clinical Practice, Hironori Nakagami,Ryuichi Morishita, Current Hypertension Reports, Current Medicine Group LLC 1, Vol. 20, No. 3, p. 22-22, 2018/03/01
脂質異常症マウスに対するPCSK9ワクチンの効果, 中神啓徳,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, Vol. 18th, 2018
新薬が変える子ども医療主に内科分野だが小児科医も知っておくべき薬高血圧:抗アンジオテンシンIIワクチン, 中神啓徳, 小児内科, Vol. 50, No. 10, 2018
老年医学領域の高度医療・未来医療老年医学領域でのワクチンの開発, 中神啓徳, 日本臨床, Vol. 76, 2018
抗セマフォリン3Eワクチンによる新規糖尿病治療法の開発, 吉田陽子,吉田陽子,清水逸平,清水逸平,中神啓徳,南野徹, 肥満研究, Vol. 24, No. Supplement, 2018
Myoferlinは脂肪分化を介して肥満を形成する, 野里陽一,鷹見洋一,中神啓徳,山本浩一,華山力成,楽木宏実, 高血圧関連疾患モデル学会学術総会抄録集, Vol. 54th, 2018
加齢性動脈硬化における脱ユビキチン化酵素CYLD(cylindromatosis)の関与, 鷹見洋一,今泉友希,山本浩一,中神啓徳,樂木宏実, 日本心血管内分泌代謝学会学術総会プログラム及び抄録集, Vol. 22nd, 2018
S100A9タンパク質を標的とした新規抗血栓ワクチンによる脳梗塞予防法の開発, 河野友裕,河野友裕,島村宗尚,島村宗尚,中神啓徳,佐々木勉,森下竜一,望月秀樹, 日本心血管内分泌代謝学会学術総会プログラム及び抄録集, (株)メディカルレビュー社, Vol. 21st, No. 2, p. 110-104, 2017/12
肥満に伴う脂肪炎症におけるマクロファージのリソソーム開口放出制御因子Myoferlinの機能解明, 野里陽一,鷹見洋一,中神啓徳,山本浩一,華山力成,楽木宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 4, p. 1379-1379, 2017/12
HVJ-Eベクターを用いた遺伝子機能スクリーニング法による血管内皮由来の新規酸化ストレス調節因子の探索, 永澤元規,鷹見洋一,中神啓徳,山本浩一,金田安史,楽木宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 4, p. 1388-1388, 2017/12
難治性皮膚潰瘍治療薬開発を目指した新規機能性ペプチドの実用化, 中神啓徳,楽木宏実, 日本老年医学会雑誌, (一社)日本老年医学会, Vol. 54, No. 4, p. 621-622, 2017/10
肥満に伴う脂肪炎症におけるマクロファージのリソソーム開口放出制御因子Myoferlinの機能解明, 野里陽一,鷹見洋一,中神啓徳,山本浩一,華山力成,楽木宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 40回, p. 342-342, 2017/10
PCSK9ワクチンの開発, 野里陽一,中神啓徳,鷹見洋一,山本浩一,森下竜一,楽木宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 40回, p. 356-356, 2017/10
HVJ-Eベクターを用いた遺伝子機能スクリーニング法による血管内皮由来の新規酸化ストレス調節因子の探索, 永澤元規,鷹見洋一,中神啓徳,山本浩一,金田安史,楽木宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 40回, p. 428-428, 2017/10
【高血圧の個別化医療】高齢者高血圧の個別化医療フレイルからワクチンまで, 勝谷友宏,中神啓徳,楽木宏実,森下竜一, 血圧, (株)先端医学社, Vol. 24, No. 9, p. 627-632, 2017/09
【循環器疾患のprecision medicine】血圧コントロールのprecision medicine, 中神啓徳,楽木宏実, 循環器内科, (有)科学評論社, Vol. 82, No. 1, p. 49-54, 2017/07
Evidence of dietary supplement on cardiovascular disease, Heart view, Vol. 21, No. 6, p. 630-635, 2017/06
新規の降圧治療法開発への期待臨床試験に向けたアンジオテンシンIIワクチンの開発, 中神啓徳,郡山弘,楽木宏実,森下竜一, 日本高血圧学会臨床高血圧フォーラムプログラム・抄録集, (NPO)日本高血圧学会, Vol. 6回, p. 105-105, 2017/05
S100A9タンパク質を標的とした新規抗血栓ワクチンによる脳梗塞予防法の開発, 河野友裕,島村宗尚,島村宗尚,中神啓徳,郡山弘,佐々木勉,坂口学,楽木宏実,望月秀樹, 日本心血管脳卒中学会学術集会プログラム・抄録集, Vol. 4th, 2017/04/24
ゲノム情報と遺伝子治療 III.遺伝子治療の現状と課題遺伝子治療の主な対象疾患循環器疾患, 中神啓徳,森下竜一, 日本臨床, Vol. 75, No. 5, 2017
α-synuclein(SNCA)の老化に伴う血管内皮機能障害における新規病態生理機能, 鷹見洋一,中神啓徳,竹屋泰,武田朱公,山本浩一,森下竜一,金田安史,樂木宏実, Dementia Japan, Vol. 31, No. 4, 2017
IL17Aを標的としたワクチンは自己免疫性糸球体腎炎モデルマウスおいて治療効果を示す, 池田裕香,郡山弘,中神啓徳,森下竜一, 日本心血管内分泌代謝学会学術総会プログラム及び抄録集, Vol. 21st, 2017
糖尿病モデルマウスにおけるプロレニンワクチンの糖尿病性合併症に対する改善効果, 林宏樹,横田陽匡,中神啓徳, 日本心血管内分泌代謝学会学術総会プログラム及び抄録集, Vol. 21st, 2017
Drug Development for Skin Ulcer by Topical Application of Functional Peptide, Vol. 15, No. 2, p. 55-60, 2017
S100A9タンパク質を標的とした新規抗血栓ワクチンによる脳梗塞予防法の開発, 河野友裕,島村宗尚,中神啓徳,郡山弘,佐々木勉,森下竜一,望月秀樹, Anti-Aging Science, Vol. 9, No. 2, 2017
パーキンソン病原因分子αシヌクレインの加齢性血管内皮機能障害における新規病態生理機能, 鷹見洋一,中神啓徳,山本浩一,森下竜一,金田安史,楽木宏実, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 92, No. 3, p. 893-893, 2017/01
Recent progression of academia-derived clinical trial in cardiovascular field, Vol. 80, No. 4, p. 247-249, 2016/10
高血圧の先進治療アンジオテンシンIIを標的とした高血圧・心不全ワクチンの開発, 中神啓徳,郡山宏,楽木宏実,森下竜一, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 39回, p. 265-265, 2016/09
高血圧症に対するアンジオテンシンIIワクチンによる新規治療法の開発, 郡山弘,中神啓徳,勝谷友宏,森下竜一,楽木宏実, 日本抗加齢医学会総会プログラム・抄録集, (一社)日本抗加齢医学会, Vol. 16回, p. 80-80, 2016/06
Therapeutic Application of an Angiotensin II Peptide Vaccine in a Middle Cerebral Artery Occlusion Model in Rats, Kouji Wakayama,Munehisa Shimamura,Jun-ichi Suzuki,Mitsuaki Isobe,Hironori Nakagami,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 47, 2016/02
Development of a Novel Anti-inflammatory and Anti-osteoplastic Peptide Based on De-loop and Ef-loop in Rankl for Treatment of Ischemic Stroke, Hitomi Kurinami,Munehisa Shimamura,Hironori Nakagami,Hideo Shimizu,Hiroshi Koriyama,Tomohiro Kawano,Hideki Mochizuki,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 47, 2016/02
パーキンソン病原因遺伝子αシヌクレインの血管老化及び血管内皮機能障害における新規病態生理機能の検討, 鷹見洋一,中神啓徳,山本浩一,森下竜一,金田安史,樂木宏実, 日本高血圧学会総会プログラム・抄録集, Vol. 39th, 2016
インクレチン関連薬の降圧効果と血管保護効果 (特集腎高血圧とインクレチン関連薬), 中神啓徳,森下竜一, 腎・高血圧の最新治療 = Current topics of kidney and hypertension : 腎・高血圧治療の今を伝える専門誌, フジメディカル出版, Vol. 5, No. 3, p. 108-113, 2016
A model of stroke and vascular injury in the brain, Munehisa Shimamura,Hironori Nakagami,Masataka Sata,Hitomi Kurinami,Kouji Wakayama,Hideki Mochizuki,Ryuichi Morishita, Mouse Models of Vascular Diseases, Springer Japan, p. 263-274, 2016/01/01
血管病としての認知症~予防はどこまで可能か?~脳血管のアンチエイジングと認知症予防, 島村宗尚,島村宗尚,中神啓徳,里直行,望月秀樹,森下竜一, 分子脳血管病, Vol. 15, No. 1, 2016/01/01
エイジングサイエンス海外文献紹介(第42回), 中神啓徳,森下竜一, Anti-aging medicine, メディカルレビュー社, Vol. 11, No. 6, p. 880-882, 2015/12
老化を科学する糖尿病・脂質異常症と認知症, 島村宗尚,島村宗尚,里直行,里直行,中神啓徳,望月秀樹,森下竜一, 最新精神医学, Vol. 20, No. 6, 2015/11/25
Translational Research of Novel Angiogenic Peptide for Wound Healing Drug; From Discovery to Clinical Trial, Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 132, 2015/11
アンジオテンシンIIワクチンによる高血圧症の新規治療法の開発, 郡山弘,中神啓徳,勝谷友宏,楽木宏実,森下竜一, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 38回, p. 362-362, 2015/10
加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(Cylindromatosis)の病態生理学的役割の検討, 今泉友希,鷹見洋一,中神啓徳,山本浩一,楽木宏実, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 38回, p. 364-364, 2015/10
Impact of surface coated magnetite used in magnetic drug delivery system on immune response, Yoshihiro Oaku,Junya Tamada,Fumihito Mishima,Yoko Akiyama,Mariana Kiomy Osako,Hiroshi Koriyama,Hironori Nakagami,Shigehiro Nishijima, Journal of Applied Physics, AMER INST PHYSICS, Vol. 117, No. 17, 2015/05/07
Development of a Novel Multifunctional Peptide with Wound Healing and Antimicrobial Activities, Vol. 32, No. 3, p. 49-56, 2015/03
Hypertension and Osteoporosis, Vol. 7, No. 1, p. 29-32, 2015/03
加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(cylindromatosis)の病態生理学的役割の検討, 今泉友希,鷹見洋一,中神啓徳,山本浩一,樂木宏実, 基礎老化研究, Vol. 39, No. 2, 2015
加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(Cylindromatosis)の病態生理学的役割の検討, 今泉友希,鷹見洋一,中神啓徳,山本浩一,楽木宏実, 高血圧関連疾患モデル学会学術総会抄録集, Vol. 51st, 2015
血清抗glial fibrillary acidic protein(GFAP)抗体を用いた1型糖尿病の早期診断の有用性についての検討, 樋口勝能,中神啓徳,PANG Zhengda,樂木宏実, 日本内分泌学会雑誌, Vol. 91, No. 2, 2015
生活習慣病・血管石灰化・骨代謝分子機構を標的とした新規治療を考察する, 中神啓徳, 日本老年医学会雑誌, Vol. 52, 2015
自己抗体に着目した新規腹部大動脈瘤発症機転の検討, 中神太志,中神啓徳, 血管, Vol. 38, No. 1, 2015
血清抗glial fibrillary acidic protein(GFAP)抗体を用いた1型糖尿病の早期診断の有用性についての検討, 樋口勝能,中神啓徳,PANG Zhengda,楽木宏実, 高血圧関連疾患モデル学会学術総会抄録集, Vol. 51st, 2015
脳血管傷害後のリモデリング過程の解析-頭蓋外血管との比較-, 島村宗尚,島村宗尚,中神啓徳,郡山弘,佐田政隆,森下竜一, 日本高血圧学会総会プログラム・抄録集, Vol. 38th, 2015
磁場回転型薬剤送達システムに関する研究, 竹内一将,三島史人,秋山庸子,西嶋茂宏,本田貴子,天満昭子,中神啓徳, 低温工学・超電導学会講演概要集, Vol. 92nd, 2015
各国の治療ガイドラインからみたRAS抑制薬の位置づけ高齢者(認知症を含む)におけるRAS抑制薬の位置づけ, 島村宗尚,里直行,中神啓徳,森下竜一, Angiotensin Research, Vol. 12, No. 1, p. 43-49, 2015/01/01
Hypertension and therapeutic vaccine, Vol. 76, No. 4, p. 380-384, 2014/10
Development of Therapeutic Vaccine for Angiotensin II, Hironori Nakagami,Hiroshi Koriyama,Ryuichi Morishita, JOURNAL OF CARDIAC FAILURE, CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, Vol. 20, No. 10, p. S151-S151, 2014/10
Anti-aging therapy for cardiovascular diseases through renin-angiotensin system, Vol. 76, No. 3, p. 264-269, 2014/09
Statin, Vol. 6, No. 2, p. 92-95, 2014/07
DEVELOPMENT OF DNA VACCINE FOR HIGH BLOOD PRESSURE - IMMUNOTHERPY FOR ANGIOTENSIN II., Hironori Nakagami,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, WILEY-BLACKWELL, Vol. 16, No. 7-8, p. 255-255, 2014/07
【骨・血管連関〜最近の進歩〜】アンチエイジングと骨・血管連関, 志水秀郎,中神啓徳,森下竜一, Clinical Calcium, (株)医薬ジャーナル社, Vol. 24, No. 7, p. 1021-1030, 2014/06
Research for Localized High-Efficient Gene Transfer by the Magnetic Force Control Using High Temperature Superconducting Bulk Magnet, Junya Tamada,Yoshihiro Oaku,Fumihito Mishima,Yoko Akiyama,Mariana KiomyOsako,Munehisa Shimamura,Hironori Nakagami,Shigehiro Nishijima, IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, Vol. 24, No. 3, 2014/06
【アンチエイジングと血圧】ARBによる骨折予防の可能性, 志水秀郎,中神啓徳,森下竜一, 血圧, (株)先端医学社, Vol. 21, No. 3, p. 228-234, 2014/03
実地医家のための抗加齢医学の臨床進歩したアンチエイジングの基礎とその実地診療への活用の実際動脈硬化とアンチエイジング, 中神啓徳,森下竜一, Medical Practice, Vol. 31, No. 7, 2014
Abetaの沈着は脳梗塞慢性期の微小循環に影響を及ぼす, 栗波仁美,島村宗尚,中神啓徳,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, Vol. 14th, 2014
なぜ加齢とともに骨は脆くなり,血管は硬くなるか?, 中神啓徳, 歯科薬物療法, Vol. 33, No. 2, 2014
治療戦略を目指した研究基礎研究脳梗塞治療標的分子細胞外基質ペリオスチン, 島村宗尚,谷山義明,中神啓徳,森下竜一, 日本臨床, Vol. 72, 2014
血管石灰化の新たな分子機構, 中神啓徳, 血管, Vol. 37, No. 1, 2014
超高齢社会におけるアンチエイジングとRAS 骨粗鬆症とRAS, 中神啓徳,森下竜一, Angiotensin Research, Vol. 11, No. 4, 2014
プロヒビチン遺伝子導入により虚血後の海馬機能障害が改善する, 栗波仁美,島村宗尚,中神啓徳,森下竜一, Anti-Aging Science, Vol. 6, No. 3, 2014
骨の老化におけるARBの新展開 (特集アンチエイジング薬としてのARBの新展開), 中神啓徳,森下竜一, Anti-aging science : 脳心血管抗加齢研究会機関誌, メディカルレビュー社, Vol. 5, No. 3, p. 262-267, 2013/12
Aging and cardiovascular diseases, NAKAGAMI Hironori, Vol. 50, No. 3, p. 184-187, 2013/09/15
Osteogenesis and atherosclerosis, Vol. 74, No. 2, p. 181-185, 2013/08
脳血管性認知症 2.脳のアンチエイジング, 島村宗尚,中神啓徳,里直行,森下竜一, Anti Aging Sci, Vol. 5, No. 2, p. 82-88, 2013/06/25
Rosuvastatin ameliorates obesity and proteinuria in zucker diabetic fatty rats, Hironori Nakagami,Takashi Shimosato,Munehisa Shimamura,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 13, p. 144-149, 2013/06/11
Study on magnetic gene transfer using HTS bulk magnet, Kota Nakagawa,Yoshihiro Ohaku,Junya Tamada,Fumihito Mishima,Yoko Akiyama,Mariana Kiomy Osako,Hironori Nakagami,Shigehiro Nishijima, Physica C: Superconductivity and its Applications, ELSEVIER SCIENCE BV, Vol. 494, p. 262-264, 2013/05/20
Chronic deposition of Aβ influences microcirculation in the chronic stage of cerebral Ischemia, Munehisa Shimamura,Naoyuki Sato,Hironori Nakagami,Mariana Kiomy Osako,Mariko Kyutoku,Kouji Wakayama,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 13, p. 77-80, 2013/04/30
Foreword: Gene therapy: Technologies and applications, Hironori Nakagami,Ryuichi Morishita, Gene Therapy: Technologies and Applications, Future Medicine Ltd., p. 3-4, 2013/03/01
Gene therapy: Technologies and applications, Ryuichi Morishita,Hironori Nakagami, Gene Therapy: Technologies and Applications, Future Medicine Ltd., p. 1-107, 2013/03/01
Plasmid DNA-based gene therapy in neurological disorders, Munehisa Shimamura,Hironori Nakagami,Hitomi Kurinami,Naoyuki Sato,Ryuichi Morishita, Gene Therapy: Technologies and Applications, p. 47-56, 2013/03/01
心血管の老化とアンチエイジング 10 アンチエイジングを目指した免疫遺伝子治療, 中神啓徳,森下竜一, Heart View, Vol. 17, No. 4, 2013
頭蓋外血管と比較した頭蓋内動脈傷害におけるリモデリング過程の解析, 島村宗尚,中神啓徳,佐田政隆,若山幸示,栗波仁美,森下竜一, 日本神経学会学術大会プログラム・抄録集, Vol. 54th, 2013
心血管イベント危険因子であるLipoprotein(a)[Lp(a)]に対する新規治療戦略~DNAワクチンの試み~, 久徳真梨子,久徳真梨子,中神啓徳,森下竜一, 血管, Vol. 36, No. 1, 2013
マウスモデルを用いた頭蓋内血管傷害におけるリモデリング過程の解析, 島村宗尚,中神啓徳,里直行,佐田政隆,栗波仁美,森下竜一, 日本老年医学会雑誌, Vol. 50, 2013
パーキンソン病関連分子αシヌクレインの新規機能-加齢性疾患としてのメタボリック症候群及びその心血管合併症の病態での役割-, 鷹見洋一,中神啓徳,神出計,山本浩一,森下竜一,金田安史,樂木宏実, 日本血管生物医学会学術集会プログラム・抄録集, Vol. 21st, 2013
Parkinson病関連分子αシヌクレインの心血管疾患への関与, 鷹見洋一,中神啓徳,山本浩一,神出計,大石充,樂木宏実, 日本老年医学会雑誌, Vol. 50, 2013
パーキンソン病原因分子αシヌクレインの加齢によるメタボリック症候群における病態生理的役割, 鷹見洋一,中神啓徳,神出計,山本浩一,森下竜一,金田安史,楽木宏実, 日本高血圧学会総会プログラム・抄録集, Vol. 36th, 2013
高血圧のワクチン治療 (特集降圧療法の新展開), 中神啓徳,森下竜一, 腎・高血圧の最新治療 = Current topics of kidney and hypertension : 腎・高血圧治療の今を伝える専門誌, フジメディカル出版, Vol. 2, No. 1, p. 36-41, 2013
【骨粗鬆症の実地診療up to date みんなで診よう生活習慣病としての骨粗鬆症】セミナー/骨粗鬆症の実地診療の進めかた生活習慣病と骨粗鬆症その診療の実際高血圧, 志水秀郎,中神啓徳,森下竜一, Medical Practice, (株)文光堂, Vol. 29, No. 11, p. 1901-1905, 2012/11
Renin angiotensin system, Vol. 35, No. 5, p. 410-416, 2012/11
Prevention of Abdominal Aortic Aneurysms by Inhibition of Renin Activity in a Rabbit Model, Takashi Miyake,Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 126, No. 21, 2012/11
Potential Contribution of RANKL System in Adipose Tissue Inflammation and Insulin Resistance, Mariana K. Osako,Futoshi Nakagami,Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 126, No. 21, 2012/11
Ultrasound microbubbles and needleless jet injector for gene transfer of naked plasmid dna, Munehisa Shimamura,Hironori Nakagami,Naoyuki Sato,Yoshiaki Taniyama,Yasuo Kunigiza,Ryuichi Morishita, Plasmids: Genetics, Applications and Health, p. 137-147, 2012/08/01
Vaccine for hypertension, Vol. 241, No. 13, p. 1098-1102, 2012/06/30
脳虚血における細胞外マトリックスペリオスチンの機能解明, 島村宗尚,谷山義明,中神啓徳,里直行,森下竜一, 日本老年医学会雑誌, Vol. 49, 2012
動脈硬化危険因子Lp(a)に対するapo(a)DNAワクチン治療効果の検討, 久徳真梨子,久徳真梨子,中神啓徳,郡山弘,郡山弘,大窄マリアナ今日美,島村宗尚,栗波仁美,栗波仁美,ほう正達,冨岡英樹,冨岡英樹,森下竜一, Anti-Aging Science, Vol. 4, No. 3, 2012
「老化とバイオマーカー」第4回骨老化とバイオマーカー, 中神啓徳, Anti-Aging Science, Vol. 4, No. 1, 2012
再狭窄予防を目的とした核酸医薬コーティング血管拡張用カテーテルの開発, 三宅隆,中神啓徳,森下竜一, 日本老年医学会雑誌, Vol. 49, 2012
Vascular Aging and Supplemental Food, 中神啓徳,森下竜一, アンチ・エイジング医学, Vol. 8, No. 2, 2012
From Bench To Bedside 第25回ペリオスチンの機能と脳梗塞治療への応用, 島村宗尚,谷山義明,中神啓徳,若山幸示,森下竜一, Vascular Medicine, Vol. 8, No. 2, 2012
Development of functional peptides with anti-aging effects and antimicrobial activity., 天満昭子,冨岡英樹,中神啓徳,森下竜一, Fragrance Journal, Vol. 40, No. 6, 2012
カルシウム拮抗薬ベニジピンの骨形成促進と骨吸収抑制による骨代謝改善作用について, 志水秀郎,中神啓徳,島村宗尚,楠博,尾崎和成,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, Vol. 12th, 2012
マウスを用いた脳梗塞におけるペリオスチンの機能解析, 島村宗尚,谷山義明,中神啓徳,三宅隆,大迫マリアナ,郡山弘,鯉渕信孝,若山幸示,森下竜一, 日本高血圧学会総会プログラム・抄録集, Vol. 35th, 2012
生活習慣病におけるRANKLの新しい知見, 中神啓徳, 松本歯学, Vol. 38, No. 2, 2012
転写因子Tbx18とWt1はSlugの発現調節を介して心外膜間葉転換を制御する, 武市真希子,二村圭祐,森雅樹,中神啓徳,金田安史, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 35th, 2012
Pitavastatin improves endothelial function and glucose metabolism in ovariectomized mice, Hironori Nakagami,Mariana Kiomy Osako,Natsuki Yasumasa,Munehisa Shimamura,Mariko Kyutoku,Futoshi Nakagami,Hiroshi Koriyama,Hideki Tomioka,Tomohiro Katsuya,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 12, p. 29-33, 2012/01/01
Lipoprotein(a) is a therapeutic target for cardiovascular disease, Mariko Kyutoku,Hironori Nakagami,Futoshi Nakagami,Hiroshi Koriyama,Mariana Kiomy Osako,Munehisa Shimamura,Takashi Miyake,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 12, p. 118-121, 2012/01/01
Screening of antihypertensive drugs for osteoclastic acid secretion and bone resorption by acridine orange, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Osako Kiomy Mariana,Mariko Kyutoku,Hiroshi Koriyama,Futoshi Nakagami,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 12, p. 161-167, 2012/01/01
Recent Progress of Therapeutic Angiogenesis and Gene Therapy, NAKAGAMI Hironori, Vol. 51, No. 4, p. 457-460, 2011/11/25
Therapeutic Lymphangiogenesis for Lymphedema by Gene Therapy of Hepatocyte Growth Factor Plasmid DNA, SAITO Yukihiro,NAKAGAMI Hironori,AZUMA Nobuyoshi,MORISHITA Ryuichi,KANEDA Yasufumi,SASAJIMA Tadahiro, Vol. 51, No. 4, p. 447-452, 2011/11/25
To prevent osteoporosis, Vol. 3, No. 3, p. 208-212, 2011/11
Impact of Angiotensin II DNA Vaccine Treatment on Blood Pressure Reduction and Its Maintenance in Spontaneously Hypertensive Rats, Hiroshi Koriyama,Hironori Nakagami,Futoshi Nakagami,Tomohiro Katsuya,Ryuichi Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 58, No. 5, p. E160-E160, 2011/11
Cross-Talk of RANKL Signaling with Renin-Angiotensin II System in Vascular Calcification and Remodeling, Mariana K. Osako,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 124, No. 21, 2011/11
Prevention of Neointimal Hyperplasia After Angioplasty Using NF-kappaB Decoy Oligodeoxynucleotides-Coated Balloon Catheter in Rabbit Restenosis Model, Takashi Miyake,Munehisa Shimamura,Hironori Nakagami,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 124, No. 21, 2011/11
【アンチエイジングからスタチンを考える】骨年齢に対するアンチエイジングスタチンと骨代謝, 志水秀郎,中神啓徳,森下竜一, Anti-aging Science, (株)メディカルレビュー社, Vol. 3, No. 2, p. 108-113, 2011/06
Metabolic syndrome and vascular dysfunction, Vol. 66, p. 1315-1323, 2011/06
Anti-aging science of statins on bone metabolism, Anti-aging science, Vol. 3, No. 2, p. 24-29, 2011/06
Anti-aging of vasculature, Vol. 39, No. 4, p. 353-356, 2011/04
Regenerative therapy, Vol. 60, No. 3, p. 383-386, 2011/03
Key Role Of Periostin In Cerebral Ischemia, Munehisa Shimamura,Yoshiaki Taniyama,Hironori Nakagami,Naoyuki Sato,Nobutaka Koibuchi,Mohammad Allahtavakoli,Kouji Wakayama,Takashi Miyake,Hideo Shimizu,Ryuichi Morishita, STROKE, LIPPINCOTT WILLIAMS & WILKINS, Vol. 42, No. 3, p. E67-E67, 2011/03
【骨粗鬆症診療アップデート2011 骨折を予防し寝たきりを回避するために】見過ごせない病態骨粗鬆症と心血管疾患との相互関係, 志水秀郎,中神啓徳,森下竜一, カレントテラピー, (株)ライフメディコム, Vol. 29, No. 2, p. 129-133, 2011/02
【患者背景を考慮した配合剤の使い分けと位置づけ】患者背景を考慮した配合剤の選択と使い分けのポイント ARB/利尿薬配合剤, 志水秀郎,中神啓徳,森下竜一, Progress in Medicine, (株)ライフ・サイエンス, Vol. 31, No. 1, p. 55-59, 2011/01
NFκBデコイコーティング血管拡張用カテーテルによる血管形成術後の再狭窄予防, 三宅隆,中神啓徳,森下竜一, 日本高血圧学会総会プログラム・抄録集, Vol. 34th, 2011
RA系とRANKLシステムの血管病態でのクロストーク, 大窄マリアナ,中神啓徳,森下竜一,楽木宏美, 日本内分泌学会雑誌, Vol. 87, No. 2, 2011
高血圧に対するワクチンの基礎的研究, 森下竜一,中神啓徳, 日本高血圧学会総会プログラム・抄録集, Vol. 34th, 2011
NFκBデコイ封入ナノ粒子をコーティングしたバルーンカテーテルによる血管形成術後の再狭窄予防, 三宅隆,中神啓徳,森下竜一, Anti-Aging Science, Vol. 3, 2011
糖尿病とアルツハイマー病の相互的病態修飾機序の解明, 武田朱公,里直行,内尾(山田)こずえ,湯久浩,守口篤,楽木宏実,中神啓徳,森下竜一, 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, Vol. 21st-41st, p. 99-99, 2011
ENDOTHELIAL FHL-2 SUPPRESSES VEGF-INDUCED PI3K/AKT PATHWAY THROUGH INTERACTION WITH SPHINGOSINE KINASE-1, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Hiroshi Koriyama,Masaki Mori,Katsuto Tamai,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1026-1026, 2010/12
ZYXIN MEDIATES ACTIN FIBER REORGANIZATION IN EPITHELIAL-MESENCHYMAL TRANSITION AND CONTRIBUTES TO ENDOCARDIAL MORPHOGENESIS, Masaki Mori,Hironori Nakagami,Nobutaka Koibuchi,Koichi Miura,Yoichi Takami,Hiroshi Koriyama,Hiroki Hayashi,Hisataka Sabe,Naoki Mochizuki,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1050-1050, 2010/12
MODIFICATION OF NOVEL ANGIOGENIC PEPTIDE, AG-30, TOWARD CLINICAL APPLICATION, Hironori Nakagami,Tomoyuki Nishikawa,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1022-1022, 2010/12
ANALYSIS ON SIGNAL PATHWAY OF AN ANTIMICROBIAL AND ANIGOGENIC PEPTIDE, AG-30, STIMULATED ENDOTHELIAL CELLS, Tomoyuki Nishikawa,Hironori Nakagami,Ryuichi Morishita,Akito Maeda,Katsuto Tamai,Yasu-fumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1027-1027, 2010/12
GENOME-WIDE ASSOCIATION STUDY IN JAPANESE POPULATION IDENTIFIES SUSCEPTIBLE LOCI FOR PERIPHERAL ARTERIAL DISEASE., Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Ken Sugimoto,Hiroshi Akasaka,Shigeyuki Saitoh,Shiro Maeda,Yusuke Nakamura,Yasufumi Kaneda,Hiromi Rakugi,Ryuichi Morishita,Kazuaki Shimamoto,Toshio Ogihara, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1046-1046, 2010/12
A NOVEL STRATEGY OF THE GENE THERAPY FOR PAD USING SMALL RNA INTERFERENCE OF COLD SHOCK DOMAIN PROTEIN A, Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Nobuyoshi Azuma,Tadahiro Sasajima,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 12, No. 12, p. 1036-1036, 2010/12
"Estrogen Prevents Aortic Calcification by inducing MGP Expression and Inhibiting BMP Expression in an Estrogen Receptor alpha Dependent Way, Mariana K. Osako,Hironori Nakagami,Hiromi Rakugi,Ryuichi Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 122, No. 21, 2010/11
高血圧 (特集骨粗鬆症診療の新しい展開) -- (各種疾患と骨粗鬆症), 中神啓徳,志水秀郎,森下竜一, 臨牀と研究, 大道学館出版部, Vol. 87, No. 7, p. 895-898, 2010/07
血管 (特集循環器疾患up to date 2010), 中神啓徳,森下竜一, Cardiovascular frontier, メディカルレビュー社, Vol. 1, No. 1, p. 47-52, 2010/05
細胞運動・ECM・細胞接着 Zyxinは上皮間葉転換においてアクチン線維再編成に関与し心内膜床の形態形成に寄与する(Cell motility, ECM and cell adhesion Zyxin Mediates Actin Fiber Reorganization in Epithelial-Mesenchymal Transition and Contributes to Endocardial Morphogenesis), 森雅樹,中神啓徳,鯉渕信孝,三浦浩一,佐邊壽孝,望月直樹,金田安史, 日本細胞生物学会大会講演要旨集, (一社)日本細胞生物学会, Vol. 62回, p. 120-120, 2010/05
脱水 (初診外来における初期診療), 郡山弘,中神啓徳, 診断と治療, 診断と治療社, Vol. 98, p. 283-287, 2010/03
RANKL System contributes the process of vascular calcification as well as osteoporosis, Mariana Osako,Hironori Nakagami,Ryuichi Morishita, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOC, Vol. 57, p. S339-S339, 2010/03
RANKL System Contributes Insulin Resistance, 中神啓徳,勝谷友宏,楽木宏実,森下竜一, 日本高血圧学会総会プログラム・抄録集, Vol. 33rd, 2010
アンチエイジング薬としてのARB ARBによる骨年齢改善, 志水秀郎,中神啓徳,森下竜一, Anti-Aging Science, Vol. 2, No. 2, 2010
テルミサルタンのPPARgamma活性化を介した内皮機能障害改善作用と脂肪肝改善作用, 中神啓徳,森下竜一, 糖尿病, Vol. 53, No. Supplement 1, 2010
Cholesterol absorption obstruction and fatty liver, 中神啓徳,森下竜一, 消化と吸収, Vol. 32, No. 2, 2010
脂肪組織においてRANKLシステムはインスリン抵抗性を惹起する-骨粗鬆症とインスリン抵抗性の共通分子基盤の解析-, 中神太志,中神啓徳,森下竜一, 糖尿病, Vol. 53, No. Supplement 1, 2010
動脈瘤の進展における慢性腎障害の影響, 三宅隆,浜田日月,島村宗尚,中神啓徳,森下竜一, 日本血管生物医学会学術集会プログラム・抄録集, Vol. 18th, 2010
Ca拮抗薬シルニジピンのN型Caチャネル阻害作用による骨吸収抑制効果について, 志水秀郎,安政奈都記,中神啓徳,楽木宏実,森下竜一, 日本血管生物医学会学術集会プログラム・抄録集, Vol. 18th, 2010
核酸医薬の全身投与による転写因子NF-kappaBとEtsの抑制が腹部大動脈瘤に及ぼす影響, 三宅隆,島村宗尚,中神啓徳,森下竜一, 日本血管生物医学会学術集会プログラム・抄録集, Vol. 18th, 2010
Combination of thiazide diuretics and angiotensin receptor blockers attenuates osteoporosis in hypertensive rats, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Mariana Kiomy Osako,Munehisa Shimamura,Takeshi Miyake,Futoshi Nakagami,Hiroshi Koriyama,Hiromi Rakugi,Ryuichi Morishita, Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, Vol. 10, p. 115-122, 2010/01/01
MICRORNA TRANSFERRED TO HUMAN ADIPOSE TISSUE-DERIVED STEM CELLS BY LENTIVIRUS VECTOR ENHANCED ADIPOGENESIS THROUGH DOWNREGULATION OF HOMEOBOX C8, Masaki Mori,Hironori Nakagami,Hiroki Hayashi,Hiroshi Koriyama,Yoichi Takami,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1167-1167, 2009/12
IDENTIFICATION OF ENDOGENOUS ANGIOGENIC REPRESSOR, FHL-2, VIA DIRECT INTERACTION WITH SPHINGOSINE KINASE-1 IN ENDOTHELIAL CELLS, Hiroki Hayashi,Hironori Nakagami,Yoichi Takami,Hiroshi Koriyama,Masaki Mori,Katsuto Tamai,Ryuichi Morishita,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1152-1153, 2009/12
COLD SHOCK DOMAIN PROTEIN A, NOVEL REPRESSOR OF TUMOR-ANGIOGENESIS AND - LYMPHANGIOGENESIS FOR CANCER GENE THERAPY, Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Nobuyoshi Azuma,Tadahiro Sasajima,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1152-1152, 2009/12
ANALYSIS OF DE NOVO ENGINEERED VARIANTS OF AG-30 FOR THE TREATMENT OF ISCHEMIC DISEASES AND INFECTIOUS DISEASES, Tomoyuki Nishikawa,Hironori Nakagami,Ryuichi Morishita,Akito Maeda,Katsuto Tamai,Kazunori Tomono,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 11, No. 12, p. 1166-1167, 2009/12
Endothelial cell growth inhibitory gene, Japanese journal of clinical medicine, Vol. 67, p. 432-435, 2009/10
Osteoporasis and vascular aging, Anti-aging science, Vol. 1, No. 1, p. 14-16, 2009/10
Osteoporosis and vascular aging, Anti-aging medicine, Vol. 5, No. 4, p. 501-504, 2009/08
エゼチミブの抗動脈硬化作用--高脂肪食ApoE欠損マウスでの解析, 中神啓徳,森下竜一, カーディオ・リピドロジー, メディカルレビュー社, Vol. 3, No. 2, p. 75-79, 2009/07
PE-062 Zyxin Progresses Epithelial-Mesenchymal Transition under the Control of Twist1 and Contributes to Endocardial Morphogenesis(PE011,Congenital Heart Disease (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Mori Masaki,Nakagami Hironori,Koibuchi Nobutaka,Miura Koichi,Takami Yoichi,Koriyama Hiroshi,Hayashi Hiroki,Sabe Hisataka,Mochizuki Naoki,Morishita Ryuichi,Kaneda Yasufumi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 73, p. 414-414, 2009/03/01
PE-275 A Novel Strategy of the Gene Therapy for PAD Using Small RNA Interference of Cold Shock Domain Protein A(PE046,Atherosclerosis (Basic, Clinical/Diagnosis) (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Saito Yukihiro,Nakagami Hironori,Azuma Nobuyoshi,Morishita Ryuichi,Kaneda Yasufumi,Sasajima Tadahiro, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 73, p. 468-468, 2009/03/01
2 Estrogen Decreases the Activation of RANK-RANKL System in Vascular Calcification(Young Investigator's Award for International Students Finalists Lecture (YIA International),The 73rd Annual Scientific Meeting of The Japanese Circulation Society), Osako Mariana K.,Nakagami Hironori,Rakugi Hiromi,Morishita Ryuichi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 73, p. 73-73, 2009/03/01
Osteoporosis and RAS, Vol. 228, No. 5, p. 529-532, 2009/01/31
Regulation of local RAS, Vol. 228, No. 5, p. 345-349, 2009/01/31
血管の石灰化と骨粗鬆症の基盤メカニズム, 中神啓徳,志水秀郎,志水秀郎,勝谷友宏,森下竜一, 日本抗加齢医学会総会プログラム・抄録集, Vol. 9th, 2009
Lp(a)による血管リモデリングに対するエストロゲンの作用, 中神太志,中神啓徳,大窄今日美,森下竜一, 日本内分泌学会雑誌, Vol. 85, No. 2, 2009
アンチエイジングにおけるRASの重要性を知る骨・筋年齢へのRASの関与を探る, 中神啓徳, Angiotensin Research, Vol. 6, No. 1, 2009
動脈硬化における脱ユビキチン化酵素の役割, 中神啓徳,鷹見洋一,勝谷友宏,樂木宏実,森下竜一, 日本老年医学会雑誌, Vol. 46, 2009
血管新生遺伝子治療の新たな治療戦略-閉塞性動脈疾患における内因性血管新生制御機構へのアプローチ, 齊藤幸裕,中神啓徳,東信良,金田安史,笹嶋唯博, 日本外科学会雑誌, Vol. 110, 2009
血管新生因子,AG-30,によるシグナル伝達経路の解析, 西川智之,中神啓徳,金田安史, 日本分子生物学会年会講演要旨集, Vol. 32nd, No. Late-Breaking Abstracts, 2009
Identification of Novel Therapeutic Targets for Metabolic Syndrome by Functional Gene Screening, H. Nakagami,T. Katsuya,Y. Takami,H. Rakugi,R. Morishita,Y. Kaneda, CLINICAL AND EXPERIMENTAL HYPERTENSION, TAYLOR & FRANCIS INC, Vol. 31, No. 6, p. 486-486, 2009
Modulation of Atherosclerotic Plaque Characteristics by Minocycline: An Evaluation by Molecular Imaging of Matrix Metalloprotainase (MMP) Expression, Satoru Ohshima,Shinichiro Fujimoto,Hironori Nakagami,Nezarn Haider,Jun Zhou,Mariana K. Osako,Ai Fujimoto,Jie Zhu,Navneet Narula,Toyoaki Murohara,Artiom Petrov,Ryuichiro Morishita,Jagat Narula, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 118, No. 18, p. S645-S645, 2008/10
OSBPL10 is Identified as a Novel Susceptible Gene for Peripheral Arterial Disease by Genome-Wide Association Study in Japan, Hiroshi Koriyama,Hironori Nakagami,Tomohiro Katsuya,Ken Sugimoto,Hidetoshi Yamashita,Yoichi Takami,Hiroshi Akasaka,Shigeyuki Saitoh,Shiro Maeda,Yusuke Nakamura,Yasufumi Kaneda,Hiromi Rakugi,Kazuaki Shimamoto,Ryuichi Morishita,Toshio Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 118, No. 18, p. S1144-S1144, 2008/10
Inhibition of cancer cell proliferation by angiotensin receptor blockers: All molecules are not the same, K. Yamamoto,C. Ho,S. Benson,H. Rakugi,T. Kuriz, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 26, p. S367-S367, 2008/06
Genom-wide association study identifies susceptible loci for atherosclesosis obliterance, H. Koriyama,H. Nakagami,T. Katsuya,K. Sugimoto,H. Yamashita,Y. Takami,M. Mori,H. Hayashi,H. Rakugi,R. Morishita,S. Maeda,Y. Nakamura,Y. Kaneda,T. Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 26, p. S139-S139, 2008/06
Pivotal roles of CYLD (cylindromatosis) as a deubiquitinating enzyme in vascular remodeling, Y. Takami,H. Nakagami,R. Morishita,T. Katsuya,H. Rakugi,Y. Kaneda,T. Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 26, p. S310-S310, 2008/06
Translational research of regenerative medicine, Vol. 35, No. 5, p. 124-126, 2008/05
OE-040 FHL-2 Expresses in Endothelial Cell and Suppresses VEGF-induced Angiogenesis Via Sphingosine Kinase-1(Arrhythmia, diagnosis/Pathophysiology/EPS(01)(A),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Hayashi Hiroki,Nakagami Hironori,Takami Yoichi,Koriyama Hiroshi,Mori Masaki,Morishita Ryuichi,Kaneda Yasufumi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 72, p. 190-190, 2008/03/01
OE-071 A Genom-Wide Association Study of SNPs in the risk of Atherosclerosis Obliterans(Heart failure, clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Koriyama Hiroshi,Nakagami Hironori,Katsuya Tomohiro,Sugimoto Ken,Yamashita Hidetoshi,Takami Yoichi,Mori Masaki,Hayashi Hiroki,Rakugi Hiromi,Morishita Ryuichi,Maeda Shiro,Nakamura Yusuke,Kaneda Yasufumi,Ogihara Toshio, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 72, p. 198-198, 2008/03/01
PJ-250 Cold shock domain protein A, novel regulator of angiogenesis in heart.(Coronary circulation, basic/clinical(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Saitou Yukihiro,Nakagami Hironori,Azuma Nobuyoshi,Morishita Ryuichi,Kaneda Yasufumi,Sasajima Tadahiro, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 72, p. 574-574, 2008/03/01
PJ-042 Pivotal Roles of CYLD (cylindromatosis) as a Deubiquitinating Enzyme in Vasculature(Atherosclerosis, basic(05)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Takami Yoichi,Nakagami Hironori,Morishita Ryuichi,Katsuya Tomohiro,Rakugi Hiromi,Kaneda Yasufumi,Ogihara Toshio, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 72, p. 520-520, 2008/03/01
OE-185 Topical application of novel angiogenic peptide, AG-30, in wound healing model(Growth factor/Cytokine(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society), Nakagami Hironori,Nishikawa Tomoyuki,Kaneda Yasufumi,Morishita Ryuichi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 72, p. 226-227, 2008/03/01
Therapeutic potential of ribbon type oligodeoxynucleotide decoy NF-kappa B in cardiovascular diseases, Mariana K. Osako,Naruya Tomita,Hironori Nakagami,Ryuichi Morishita, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 44, No. 2, p. 443-443, 2008/02
テルミサルタンの抗動脈硬化作用の検討, 中神啓徳,鷹見洋一,郡山弘,郡山弘,勝谷友宏,樂木宏実,森下竜一, 日本高血圧学会総会プログラム・抄録集, Vol. 31st, 2008
ゲノムワイド関連解析による閉塞性動脈硬化症感受性遺伝子座の同定, 郡山弘,中神啓徳,勝谷友宏,杉本研,山下英俊,鷹見洋一,赤坂憲,斎藤重幸,前田士朗,中村裕輔,金田安史,樂木宏実,森下竜一,島本和明,荻原俊男,荻原俊男, 日本高血圧学会総会プログラム・抄録集, Vol. 31st, 2008
循環器のアンチエイジング老化と心疾患,その予防, 中神啓徳,森下竜一, 循環plus, Vol. 8, No. 8, 2008
心筋虚血時のCold shock domain protein Aによる血管新生調節機構, 齊藤幸裕,中神啓徳,東信良,金田安史,笹嶋唯博, 日本外科学会雑誌, Vol. 109, 2008
NPC1L1(Niemann-Pick C1 Like 1)[外因性コレステロール吸収調節に重要な分子として注目されるNPC1LI], 中神啓徳,森下竜一, Cardio-Lipidology, Vol. 2, No. 1, 2008
Small muscle protein,X-linked(SMPX)の心臓における機能の解析, 鷹見洋一,中神啓徳,森下竜一,勝谷友宏,樂木宏実,金田安史,荻原俊男, 日本高血圧学会総会プログラム・抄録集, Vol. 31st, 2008
血管の再生と炎症の関連を探る (特集血管病の発症と炎症を探る--新たな視点から), 中神啓徳,森下竜一, Vascular medicine, 先端医学社, Vol. 3, No. 4, p. 339-344, 2007/10
Anti-inflammatory and anti-proliferative action of cylindromatosis (CYLD) in atherosclerosis as a deubiquitinating enzyme, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 116, No. 16, p. 108-108, 2007/10
Potential contribution of action of renin angiotensin system to bone metabolism, Hironori Nakagami,Mariana Kiomy Osaka,Hideo Shimizu,Rie Hanayama,Ryuichi Morishita, Current Hypertension Reviews, BENTHAM SCIENCE PUBL LTD, Vol. 3, No. 2, p. 129-132, 2007/05
OE-206 Development of Ribbon Type NF-κ B Decoy Oligodeoxynucleotides(Genetics/Genetically engineered models/Gene therapy-1(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society), Osako Mariana,Tomita Naruya,Nakagami Hironori,Ogihara Toshio,Morishita Ryuichi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 71, p. 202-203, 2007/03/01
OJ-195 Pivotal Roles of Deubiquitinating Enzymes UCHL1, HAUSP, and CYLD in Vasculature as an Anti-proliferative and Anti-inflammatory Effect(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society), Takami Yoichi,Nakagami Hironori,Katsuya Tomohiro,Rakugi Hiromi,Morishita Ryuichi,Kaneda Yasufumi,Ogihara Toshio, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 71, p. 302-302, 2007/03/01
3 Functional Analysis of Novel Antimicrobial Peptide, AG (Angiogenic Peptide)-30, with Angiongenic Property, toward Clinical Application(The 71st Annual Scientific Meeting of the Japanese Circulation Society), Nakagami Hironori,Nishikawa Tomoyuki,Morishita Ryuichi,Tabata Yasuhiko,Tatsu Yoshihiro,Tomono Kazunori,Ogihara Toshio,Kaneda Yasufumi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 71, p. 52-52, 2007/03/01
Favorable effects of statins beyond lipid lowering, Hironori Nakagami,Yasufumi Kaneda,Tosbio Ogihara,Ryuichi Morishita, FUTURE LIPIDOLOGY, FUTURE MEDICINE LTD, Vol. 1, No. 1, p. 75-80, 2007/02
脱ユビキチン化酵素CYLD(cylindromatosis)の血管における機能, 鷹見洋一,中神啓徳,森下竜一,勝谷友宏,楽木宏実,金田安史,荻原俊男, 日本高血圧学会総会プログラム・抄録集, Vol. 30th, 2007
新規血管・リンパ管新生抑制分子Cold shock domain protein A-新規分子を用いた癌増殖,転移抑制への次世代の治療戦略-, 齊藤幸裕,中神啓徳,黒岡正之,東信良,金田安史,笹嶋唯博, 日本外科学会雑誌, Vol. 108, 2007
Pivotal role of deubiquitinating enzymes, UCHL1 (Ubiquitin Carboxyl-terminal Hydrolase L1) and CYLD (Cylindromatosis) in vascular remodeling, 鷹見洋一,中神啓徳,森下竜一,勝谷友宏,楽木宏実,金田安史,荻原俊男, 日本内分泌学会雑誌, Vol. 83, No. 2, 2007
Development of high throughput functional screening of cardiovascular therapeutic genes using the HVJ-E vector: Analysis of a novel angiogenic peptide, AG-30, Tomoyuki Nishikawa,Hironori Nakagami,Katsuto Tamai,Yasufumi Kaneda, JOURNAL OF GENE MEDICINE, JOHN WILEY & SONS LTD, Vol. 8, No. 12, p. 1443-1444, 2006/12
Novel high through-put functinal screening by HVJ-E - targetting of antivascular remodeling factors in hypertension, Yoichi Takami,Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 237-237, 2006/12
HMG-CoA reductase inhibitor (fluvastatin) ameliorates the activation of osteoclast as an antioxidant, Rie Hanayama,Hironori Nakagami,Hideo Shimuzu,Natsuki Yasumasa,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 398-398, 2006/12
Angiotensin converting enzyme inhibitors (imidapril) ameliorates the osteoporosis in rat ovariectomized model, Natsuki Yasumasa,Hironori Nakagami,Hideo Shimizu,Rie Hanayama,Toshio Ogihara,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 257-257, 2006/12
Association of a gene polymorphism of novel Z-disc protein, myospryn, and left ventricular diastolic dysfunction, Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Yoichi Takami,Hiroshi Akasaka,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 381-381, 2006/12
Hepatocyte growth factor ameliorates secondary lymphedema via promotion of lymphangiogenesis., Yukihiro Saito,Hironori Nakagami,Ryuichi Morishita,Yoichi Takami,Katsuto Tamai,Yasuhumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 408-408, 2006/12
Angiotensin II receptor blockade (RNH-6270) ameliorates osteoporosis, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Rie Hanayama,Ryuichi Morishita, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 100-100, 2006/12
Ubiquitincarboxyl-terminalesterase L1, causative gene of Parkinson's disease, has anti-inflammatory action in vascular cells, Yoichi Takami,Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 24, p. 54-55, 2006/12
Development of functional gene screening for therapeutic angiogenesis in next generation, NAKAGAMI Hironori,KANEDA Yasufumi,MORISHITA Ryuichi, Vol. 29, No. 3, p. 81-84, 2006/10/13
gamma-secretase is new therapeutic target for anti-angiogenic therapy, Hiroki Hayashi,Hironori Nakagami,Yukihiro Saito,Yoichi Talkami,Tomoyuki Nishikawa,Naoyuki Sato,Ryuichi Morishita,Yasufumi Kaneda, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 4, p. E94-E94, 2006/10
Ubiquitin carboxyl-terminal esterase L1, causative gene of Parkinson's disease, modulates anti-inflammatory-mediated vascular remodeling, Yoichi Takami,Hironori Nakagami,Ryuichi Morishita,Tomohiro Katsuya,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 114, No. 18, p. 257-257, 2006/10
Gene polymorphism of novel Z-disc protein, myospryn, is associated with left ventricular hypertrophy and diastolic dysfunction, Hironori Nakagami,Tomohiro Katsuya,Ryuichi Morishita,Yasushi Kikuchi,Hiroshi Akasaka,Hiromi Rakugi,Yasufumi Kaneda,Toshio Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 48, No. 4, p. E78-E78, 2006/10
Development of High Throughput Functional Screening of Cardiovascular Therapeutic Genes Using the HVJ-E Vector, Tomoyuki Nishikawa,Hironori Nakagami,Atsuhi Matsuki,Yukihiro Saito,Ryuichi Morishita,Katsuto Tamai,Yasufumi Kaneda, MOLECULAR THERAPY, NATURE PUBLISHING GROUP, Vol. 13, p. S336-S336, 2006/05
NFkB Decoy Oligodeoxynucleotides Inhibit Osteoclast Differentiation and Activation In Vitro and Improve Osteoporosis of Ovariectomized and Vitamin C Difficient Rat Models, Hideo Shimizu,Hironori Nakagami,Natsuki Yasumasa,Rie Hanayama,Toshio Ogihara,Ryuichi Morishita, MOLECULAR THERAPY, NATURE PUBLISHING GROUP, Vol. 13, p. S275-S275, 2006/05
Hepatocyte growth factor (HGF)によるリンパ管新生作用およびリンパ浮腫に対する遺伝子治療, 齊藤幸裕,中神啓徳,森下竜一,金田安史,東信良,笹嶋唯博, 日本外科学会雑誌, 一般社団法人日本外科学会, Vol. 107, No. 2, p. 244-244, 2006/03/05
PE-383 HGF Gene Therapy Ameliorates Secondary Lymphedema through Lymphangiogenesis(Genetics/Genetically engineered models/Gene therapy-2 (M) PE64,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Saito Yukihiro,Nakagami Hironori,Takami Yoichi,Morishita Ryuichi,Ogihara Toshio,kaneda Yasufumi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 70, p. 429-429, 2006/03/01
PJ-752 A Novel Model of Vasculogenesis From ES Cells for Vascular Research and Regenerative Medicine(Development and differentiation-4 (M) PJ129,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Nakagami Hironori,Takeya Yasushi,Ogihara Toshio,Morishita Ryuichi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 70, p. 675-675, 2006/03/01
PJ-098 Ubiquitin C-terminal Hydroxylase L1 (UCHL1), the Causative Genes of Inherited Parkinson's Disease, Has an Anti-inflammatory Action in Endothelial Cells(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society), Takami Yoichi,Nakagami Hironori,Katsuya Tomohiro,Rakugi Hiromi,Morishita Ryuichi,Kaneda Yasufumi,Ogihara Toshio, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 70, p. 513-514, 2006/03/01
フルバスタチンの破骨細胞活性抑制機構-抗酸化作用の検討-, 華山りえ,志水秀郎,安政奈都記,中神啓徳,森下竜一, 日本内分泌学会雑誌, Vol. 82, No. 1, 2006
骨代謝におけるレニン・アンジオテンシン系の関与, 志水秀郎,中神啓徳,安政奈都記,華山りえ,荻原俊男,森下竜一, 日本内分泌学会雑誌, Vol. 82, No. 1, 2006
Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells, H Nakagami,K Maeda,Y Kaneda,T Ogihara,R Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 46, No. 4, p. 867-867, 2005/10
Identification of novel angiogenic peptide, Ag-30, H Nakagami,T Nishikawa,R Morishita,Y Kaneda, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 112, No. 17, p. U256-U256, 2005/10
【高血圧発症の分子機構の新展開】老化症としての高血圧骨粗鬆症との関連, 中神啓徳,志水秀郎,森下竜一, 分子心血管病, (株)先端医学社, Vol. 6, No. 4, p. 387-391, 2005/08
Development of Novel High Throughput Functional Screening System Based on HVJ-E Vector : Screening of Anti-vascular Remodeling Factor in Hypertension(Hypertension, Basic 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society), Takami Yoichi,Nakagami Hironori,Katsuya Tomohiro,Rakugi Hiromi,Morishita Ryuichi,Kaneda Yasufumi,Ogihara Toshio, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 69, p. 538-538, 2005/03/01
A Novel Autologous Cell Therapy into Ischemic Limb Diseases by Adipose Tissue-derived Stromal Cells through Growth Factor Secretion(Vasoactive Compound/Growth Factor/Cytokine 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society), Nakagami Hironori,Maeda Kazuhisa,Morishita Ryuichi,Kaneda Yasufumi,Ogihara Toshio, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 69, p. 171-171, 2005/03/01
Hepatocyte growth factor(HGF)によるリンパ管新生作用, 斉藤幸裕,斉藤幸裕,中神啓徳,鷹見洋一,森下竜一,金田安史,東信良,笹嶋唯博, 日本高血圧学会総会プログラム・抄録集, Vol. 28th, 2005
HVJ-Eベクターを用いたHigh Throughput Screeningによる新規遺伝子機能スクリーニング-血管リモデリング抑制遺伝子の検索-, 鷹見洋一,中神啓徳,勝谷友宏,楽木宏実,森下竜一,金田安史,荻原俊男, 日本高血圧学会総会プログラム・抄録集, Vol. 28th, 2005
脂肪由来未分化細胞を用いた血管新生細胞治療, 中神啓徳,前田和久,森下竜一,荻原俊男,金田安史, 再生医療, Vol. 4, 2005
骨粗しょう症におけるレニン・アンジオテンシン系の解析, 中神啓徳,志水秀郎,華山りえ,安政奈都記,荻原俊男,森下竜一, 日本内分泌学会雑誌, Vol. 81, No. 2, 2005
強磁性粒子を用いた新規遺伝子導入法の開発と評価, 寺園文吾,武田真一,泉佳伸,江間喜美子,西嶋茂宏,金田安史,中神啓徳, 日本ME学会大会論文集, Vol. 44th, 2005
【サイトカインの臨床薬理】転写調節因子Interferon Regulatory Factor-1(IRF-1)による血管リモデリング機構の解明, 堀内正嗣,鈴木純,日和田邦男,岩井將,中神啓徳, 臨床薬理の進歩, (公財)臨床薬理研究振興財団, No. 25, p. 66-70, 2004/07
Development of HVJ-E high throughput gene function screening system: Screening of endothelial cell growth factors, T Nishikawa,H Nakagami,CY Yo,Y Kaneda, MOLECULAR THERAPY, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 9, p. S113-S114, 2004/05
OE-211 Differentiation of ES cells into sprouting vessels on Matrigel without growth factors(Angiogenesis 1 (M) : OE26)(Oral Presentation (English)), Nakagawa Namika,Nakagami Hironori,Hayashi Shinnichiro,Ogihara Toshio,Morishita Ryuichi, Circulation journal : official journal of the Japanese Circulation Society, Japanese Circulation Society, Vol. 68, p. 192-192, 2004/03/01
Statins attenuate cardiac hypertrophy through inhibition of NOX2-containing NADPH oxidase, H Nakagami,R Morishita,Y Kaneda,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 22, p. S115-S115, 2004/02
Pharmacogenomics and Translational Research, 中神啓徳,浦聖恵,森下竜一, 臨床薬理, Vol. 35, No. 3, 2004
磁性高分子を用いた新規遺伝子導入法の開発, 寺園文吾,武田真一,泉佳伸,江間喜美子,西嶋茂宏,金田安史,中神啓徳, 日本ME学会秋季大会論文集, Vol. 18th, 2004
細胞への遺伝子導入効率向上に最適な表面修飾法の検討, 三島史人,武田真一,泉佳伸,西嶋茂宏,中神啓徳,金田安史, 日本ME学会秋季大会論文集, Vol. 18th, 2004
磁性高分子を用いた次世代Drug Delivery System(DDS)の開発, 中神啓徳,金田安史,三島史人,武田真一,西嶋茂弘, 日本ME学会秋季大会論文集, Vol. 18th, 2004
Statins attenuate angiotensin II-Induced cardiac hypertrophy through inhibition of gp91PHOX-Containing NADPH oxidase, H Nakagami,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 108, No. 17, p. 45-45, 2003/10
Inhibition of angiotensin II-induced cardiac hypertrophy by antioxidants, M Takemoto,H Nakagami,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 107, No. 19, p. E183-E183, 2003/05
スタチンはNADPH oxidaseを介した酸化ストレスの抑制により心肥大を抑制する, 中神啓徳,森下竜一,萩原俊男,金田安史,LIAO J K, 日本内分泌学会雑誌, Vol. 79, No. 2, 2003
Ventricular septal defects, cardiomyopathy, and vascular smooth muscle dysfunction in mice lacking the transcription factor CHF1/Hey2, MT Chin,Y Sakata,Y Kiriyama,CN Kamei,H Nakagami,ZP Chen,DI Simon,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 19, p. I-I, 2002/11
Ventricular septal defects, cardiomyopathy and vascular smooth muscle dysfunction in mice lacking the transcription factor CHF1/Hey2, MT Chen,Y Sakata,Y Kiriyama,CN Kamei,H Nakagami,ZP Chen,JK Liao, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 19, p. 229-229, 2002/11
Role of the expression of distinct AT(1) receptor and AT(2) receptor in pregnancy-induced hypertension, Y Takeda-Matsubara,H Nakagami,M Iwai,TX Cui,T Shiuchi,L Wu,LJ Ming,M Ito,M Horiuchi, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 20, p. S36-S36, 2002/06
血圧及び水分調節における中枢性アンジオテンシンII受容体サブタイプの役割:アンジオテンシンII受容体遺伝子欠損マウスを用いた研究, 岩井將,Li Zhen,中神啓徳,Wu Lan,Cui Tai-Xing,Chen Rui,鈴木純,Liu Hong-Wei,志内哲也,松原裕子, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 24回, p. 32-32, 2001/10
血管傷害モデルにおけるアンジオテンシンII受容体サブタイプのアポトーシス制御作用 AT1受容体遺伝子欠損マウス,AT2受容体遺伝子欠損マウスを用いた検討, 鈴木純,岩井將,中神啓徳,Wu Lan,Chen Rui,濱田希臣,日和田邦男,堀内正嗣, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 24回, p. 56-56, 2001/10
炎症性血管傷害に及ぼすACE阻害薬Imidaprilの作用におけるNOの関与 TA1a受容体遺伝子欠損マウスを用いた検討, 陳睿,岩井將,中神啓徳,呉蘭,浜井盟子,鈴木純,劉宏偉,志内哲也,松原裕子,菅谷健, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 24回, p. 113-113, 2001/10
炎症性血管リモデリングに及ぼすHMG-CoA reductase inhibitor CerivastatinとAT1受容体拮抗薬Candesartanの相乗作用, 岩井將,Li Zhen,中神啓徳,Wu Lan,Cui Tai-Xing,Chen Rui,鈴木純,Liu Hong-Wei,浜井盟子,志内哲也, 日本高血圧学会総会プログラム・抄録集, (NPO)日本高血圧学会, Vol. 24回, p. 44-44, 2001/10
Possible roles of interaction of AT1 and AT2 receptors in preeclampsia: Study using AT1 receptor null mice and AT2 receptor null mice, Y Takeda-Matsubara,H Nakagami,M Iwai,TX Cui,T Shiuchi,L Wu,LJ Ming,M Ito,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 17, p. 277-277, 2001/10
Effects of ACE inhibitor, imidapril, on vascular remodeling after cuff placement in AT1A receptor null mouse: Involvement of nitric oxide in the action of ACE inhibitor, R Chen,M Iwai,L Wu,H Nakagami,Z Li,M Hamai,J Suzuki,Y Takeda-Matsubara,T Shiuchi,T Sugaya,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 17, p. 90-91, 2001/10
Role of angiotensin II receptor subtypes in the regulation of apoptosis in vascular remodeling in vivo., J Suzuki,M Iwai,W Lan,H Nakagami,T Sugaya,T Seiyaku,M Hamada,K Hiwada,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 104, No. 17, p. 296-296, 2001/10
血管新生の基礎と臨床 HGFのシグナル伝達, 中神啓徳, 最新医学, Vol. 56, No. 8, 2001
血管病への遺伝子治療の展望, 中神啓徳,堀内正嗣, 愛媛医学, Vol. 20, No. 1, 2001
フォーラム高血圧と臓器障害エストロゲン受容体によるホスファターゼの活性化とAT<sub>1</sub>受容体とのクロストーク, 松原裕子,中神啓徳,岩井将,さい泰興,志内哲也,伊藤昌春,堀内正嗣, 血圧, Vol. 8, No. 7, 2001
At1 receptor blocker improves pressure-overload induced cardiac remodeling via AT1 receptor inhibition and AT2 receptor stimulation: Study using AT2 receptor null mice, L Wu,M Iwai,M Akishita,H Nakagami,M De Gasparo,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 72-72, 2000/10
Improvement of inflammatory vascular injury by AT(1) receptor blocker depends on AT(1) receptor blockade and AT(2) receptor stimulation: Evaluation of the role of AT(2) receptor using AT(2) receptor null mice, L Wu,M Iwai,H Nakagami,R Chen,M Akishita,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 275-275, 2000/10
Estrogen activates tyrosine and serine/threonine phosphatases and antagonizes the growth promoting effect of angiotensin II AT1 receptor in vascular smooth muscle cells, Y Takeda,H Nakagami,M Iwai,M Akishita,TX Cui,M Ito,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 180-180, 2000/10
Novel therapeutic strategy for restenosis using ribozyme oligonucleotides against transforming growth factor-beta, K Yamamoto,R Morishita,N Tomita,H Nakagami,M Aoki,J Higaki,Y Kaneda,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 36, No. 4, p. 728-729, 2000/10
Signaling of AT2 receptor-mediated cell death in fetal vascular smooth muscle cells pivotal role of SHP-1 via inhibition of ERK and AKT, TX Cui,H Nakagami,M Iwai,C Nahmias,T Shiuchi,K Toku,Y Kondo,Y Takeda,L Daviet,M Horiuchi, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 52-52, 2000/10
Hgf/NK4 as potential antagonist for diabetic retinopathy: Inhibition of VEGF-induced angiogenesis by HGF/NK4., M Nakabayashi,H Nakagami,K Yamamoto,M Aoki,Y Kaneda,R Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 249-249, 2000/10
Hypoxia induced renal epithelial cell death through caspase-dependent pathway: Role of bcl-2, bcl-xL and bax in tubular injury, K Yamamoto,R Morishita,N Tomita,Y Taniyama,M Aoki,H Nakagami, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 102, No. 18, p. 517-517, 2000/10
Mitogenic and anti-apoptotic actions of hepatocyte growth factor through ERK, STAT3 and AKT in human aortic endothelial cells, H Nakagami,R Morishita,K Yamamoto,Y Taniyama,M Aoki,Y Kaneda,M Horiuchi,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 36, No. 4, p. 708-708, 2000/10
0699 肝細胞増殖因子(HGF)による血管内皮細胞死抑制作用のメカニズム解明, 中神啓徳,森下竜一,山本圭,谷山義明,青木元邦,山崎慶太,荻原俊男,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 64, p. 361-361, 2000/03/01
0698 転写因子ets-1を介した肝細胞増殖因子(HGF)の抗線維化および血管新生作用, 谷山義明,青木元邦,中神啓徳,山本圭,山崎慶太,荻原俊男,森下竜一,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 64, p. 361-361, 2000/03/01
0432 TGF-βリボザイムを用いた血管再狭窄に対する遺伝子治療の可能性, 山本圭,冨田奈留也,守口篤,檜垣実男,荻原俊男,森下竜一,谷山義明,中神啓徳,松下英嗣,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 64, p. 293-293, 2000/03/01
0433 転写因子E2Fに対するおとり遺伝子 (デコイ)によるミニブタ冠動脈バルーン傷害後再狭窄モデルにおける再狭窄抑制機構の検討, 中村俊紀,松下英嗣,青木元郎,中神啓徳,谷山義明,守口篤,檜垣實男,荻原俊男,森下竜一, Japanese circulation journal, 社団法人日本循環器学会, Vol. 64, p. 293-293, 2000/03/01
P034 高血糖刺激による血管内皮細胞死のメカニズムについて, 中神啓徳,森下竜一,山本圭,青木元邦,谷山義明,山崎慶太,荻原俊男,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 64, p. 467-467, 2000/03/01
P872 低酸素状態におけるヒト低酸素状態における尿細管上皮細胞死の分子機構の検討, 山本圭,谷山義明,中神啓徳,冨田奈留也,萩原俊男,森下竜一,金田安史,吉村紳一, Japanese circulation journal, 社団法人日本循環器学会, Vol. 64, p. 678-678, 2000/03/01
P079 ラット及びウサギ閉塞性動脈硬化症(ASO)モデルへの肝細胞増殖因子(HGF)遺伝子の導入による血管新生作用 : HGF蛋白動脈内投与との比較, 谷山義明,青木元邦,中神啓徳,山本圭,山崎慶太,荻原俊男,森下竜一,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 64, p. 478-478, 2000/03/01
低酸素状態におけるHGF(Hepatocyto Growth Factor)などの細胞増殖因子の血管内皮細胞傷害抑制についての分子機構の検討, 山本圭,林真一郎,松下英嗣,中神啓徳,谷山義明,檜垣実男,荻原俊男,森下竜一,金田安史, Japanese Circulation Journal, (一社)日本循環器学会, Vol. 64, No. Suppl.I, p. 435-435, 2000/03
ACE阻害薬による組織特異的な糖取り込み促進作用機構の解明ブラジキニンおよびNOの役割, 志内哲也,中神啓徳,岩井将,さい泰興,武田裕子,近藤容子,箕越靖彦,堀内正嗣, 日本内分泌学会雑誌, Vol. 76, No. 2, 2000
ラット頚動脈バルーン傷害モデルにおけるNFkBデコイによる再狭窄予防, 林克彦,吉村紳一,坂井昇,森下竜一,金田安史,中神啓徳,松本圭子,山本圭,荻原俊男, Japanese Circulation Journal, Vol. 64, No. Supplement 1, 2000
Molecular mechanism of cell death pathway induced by high D-glucose in human endothelial cell, H Nakagami,R Morishita,K Yamamoto,M Horiuchi,Y Kaneda,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S199-S199, 2000
Pre-clinical studies of therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hind limb ischemia models, Y Taniyama,R Morishita,M Aoki,H Nakagami,K Yamamoto,K Yamasaki,Y Kaneda,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S182-S182, 2000
Induction of transcription factor ETS-1 in endothelial cells by hepatocyte growth factor (HGF), N Tomita,R Morishita,H Nakagami,Y Taniyama,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S181-S181, 2000
Hypoxia induced renal epithelial cell death through caspase-dependent pathway: Role of bcl-2, Bcl-x/L and Bax in tubular injury, K Yamamoto,R Morishita,N Tomita,H Nakagami,Y Taniyama,M Aoki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 18, p. S99-S99, 2000
Phosphrylation of p38 MAP kinase in the gown-stream of Bax-caspase 3 pathway leads to apoptosis induced by high D-glucose in human endothelial cells: Cross-talk between p38MAPK and caspase proteases, H Nakagami,K Yamamoto,S Yoshimura,R Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 64-64, 1999/11
Hypoxia induced apoptosis through oxidative stress-NF kappa B-mediated Bax translocation in human aortic endothelial cells, T Nata,H Matsushita,H Nakagami,M Aoki, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 267-267, 1999/11
Endothelial apoptosis induced by high D-glucose was prevented by hepatocyte growth factor through up-regulation of Bcl-2 and inhibition of translocation of Bax, H Nakagami,K Yamamoto,S Yoshimura, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 267-267, 1999/11
Reduced risk for thromboembolism in atrial fibrillation and mitral regurgitation - Reply, K Yamamoto,H Nakagami,U Ikeda,K Shimada, AMERICAN HEART JOURNAL, MOSBY-YEAR BOOK INC, Vol. 138, No. 5, p. 998-999, 1999/11
Cardio-protective effects of hepatocyte growth factor (HGF) gene transfer into the myocardium of cardiomyopathic hamster (Bio 14.6): novel gene therapy strategy for cardiomyopathy, Y Taniyama,M Aoki,T Nata,H Nakagami,R Morishita, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 100, No. 18, p. 47-48, 1999/11
HGFによる血管内皮再生療法の試み (10月第5特集 Vascular biology--分子生物学と病態・治療) -- (血管と生理活性物質のトピックス), 中神啓徳,森下竜一, 医学のあゆみ, 医歯薬出版, Vol. 191, No. 5, p. 453-457, 1999/10/30
Accumulation of cyclic AMP inhibited growth of human aortic vascular smooth muscle cells, accompanied by induction of anti-oncogenes, p53 and p21, and an endothelium-specific growth factor, hepatocyte growth factor, S Hayashi,H Nakagami,R Morishita, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 34, No. 2, p. 343-343, 1999/08
サイクリックAMP(cAMP)による血管平滑筋細胞増殖抑制癌抑制遺伝子p53及びp21増加を介した細胞周期停止とアポトーシス誘導, 青木元邦,中村俊紀,森下竜一,林真一郎,松下英嗣,中神啓徳,谷山義明,守口篤,檜垣実男,荻原俊男, 動脈硬化, (一社)日本動脈硬化学会, Vol. 26, No. 8, p. 146-146, 1999/05
0598 血管平滑筋細胞と単球の共培養における肝細胞増殖因子(HGF)の発現と誘導, 岡田基,北條行弘,池田宇一,島田和幸,中神啓徳,森下竜一,中村敏一, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 299-299, 1999/03/01
P620 アンジオテンシン阻害による心筋症ハムスターの心筋障害抑制効果 : 抗線維化因子としての肝細胞増殖因子(HGF)の関与, 谷山義明,松下英嗣,青木元邦,中神啓徳,冨田奈留也,中村俊紀,檜垣實男,萩原俊男,森下竜一, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 605-605, 1999/03/01
P576 転写因子E2Fに対するおとり遺伝子(デコイ)によるミニブタ冠動脈バルーン傷害後再狭窄モデルに対する遺伝子治療の可能性, 中村俊紀,森下竜一,松下英嗣,青木元邦,中神啓徳,谷山義明,守口篤,檜垣實男,萩原俊男,左近上博司, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 594-594, 1999/03/01
P129 低酸素により誘導された内皮細胞死における転写調節因子NFkBの役割 : 心筋梗塞発症における内皮のバリアーとしての役割, 松下英嗣,谷山義明,青木元邦,中神啓徳,中村俊紀,守口篤,檜垣實男,荻原俊男,森下竜一,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 481-481, 1999/03/01
0775 高血糖刺激による血管内皮細胞の細胞死にはp38MAPKの活性化が関与する, 中神啓徳,森下竜一,松下英嗣,山本圭,谷山義明,中村好男,駒井則夫,中村俊紀,守口篤,檜垣實男,荻原俊男, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 343-343, 1999/03/01
P319 糖尿病性内皮機能障害の原因としての局所肝細胞増殖因子(HGF)低下とプロスタグランジンI_2の組織HGF発現増加を介する血管拡張能改善, 松本圭子,森下竜一,守口篤,中村好男,駒井則夫,中神啓徳,檜垣實男,荻原俊男,左近上博司, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 529-529, 1999/03/01
1058 TGF-βリボザイムを用いた血管再狭窄に対する遺伝子治療の可能性, 山本圭,冨田奈留也,松下英嗣,谷山義明,中神啓徳,守口篤,檜垣實男,荻原俊男,森下竜一,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 415-415, 1999/03/01
0143 がん抑制遺伝子p53喪失は新生内膜肥厚を誘導する : ラット頚動脈及びヒト血管平滑筋細胞での検討, 松下英嗣,青木元邦,谷山義明,中神啓徳,守口篤,檜垣寅男,萩原俊男,森下竜一,金田安史,下里貴, Japanese circulation journal, 社団法人日本循環器学会, Vol. 63, No. 1, p. 183-183, 1999/03/01
サイクリックAMP(cAMP)による血管平滑筋細胞増殖抑制癌抑制遺伝子p53及びp21増加を介した細胞周期停止とアポトーシス誘導, 中村俊紀,森下竜一,林真一郎,松下英嗣,青木元邦,中神啓徳,谷山義明,守口篤,檜垣實男,荻原俊男, Japanese Circulation Journal, (一社)日本循環器学会, Vol. 63, No. Suppl.I, p. 205-205, 1999/03
血管内皮細胞における肝細胞増殖因子(HGF)の情報伝達系の解明 HGFはbcl-2を増加させ,ERKとAktをリン酸化する, 中神啓徳,森下竜一,林真一郎,松下英嗣,山本圭,中村好男,冨田奈留也,守口篤,檜垣實男,荻原俊男, Japanese Circulation Journal, (一社)日本循環器学会, Vol. 63, No. Suppl.I, p. 174-174, 1999/03
Importance of transcriptional factor NFkB, in hypoxia-induced death and apoptosis in human aortic endothelial cells., H Matsushita,R Morishita,H Nakagami,Y Taniyama,J Higaki, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 98, No. 17, p. 38-38, 1998/10
Anti-fibrotic action of hepatocyte growth factor by up-regulation of matrix metalloprotease-1 and urokinase-type plasminogen activator (uPA) in human fibroblasts and vascular smooth muscle cells (VSMC)., Y Taniyama,K Matsumoto,H Nakagami, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 98, No. 17, p. 810-810, 1998/10
Beneficial angiogenesis induced by over-expresssion of human hepatocyte growth factor (HGF) in non-infarcted and infarcted myocardium: Potential gene therapy for myocardial infarction, M Aoki,R Morishita,H Matsushita,S Hayashi,Y Taniyama,H Nakagami,T Nakamura,T Ogihara, CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 98, No. 17, p. 321-321, 1998/10
Molecular mechanisms of high D-glucose induced apoptosis in human endothelial-cells (EC): Contribution of mitogen-activated protein kinase (MAPK) cascade and apoptosis related genes, bax and bcl-2, H Nakagami,R Morishita,H Matsushita,S Hayashi,N Tomita,Y Taniyama,K Yamamoto,A Moriguchi,J Higaki,T Ogihara, HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 32, No. 3, p. 620-620, 1998/09
Role of hepatocyte growth factor (HGF) on endothelial cell damage in diabetes mellitus (DM) through its anti-apoptotic action, H Nakagami,R Morishita,H Matsushita,S Hayashi,K Moriguchi,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 16, p. S58-S58, 1998/06
Prevention of hypoxia-induced endothelial cell death by hepatocyte growth factor (HGF) through anti-apoptotic action, S Hayashi,R Morishita,H Matsushita,H Nakagami,A Moriguchi,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 16, p. S66-S66, 1998/06
Importance of transcriptional factor NF kappa B in hypoxia-induced death and apoptosis of human aortic endothelial cells, H Matsushita,R Morishita,S Hayashi,Y Taniyama,N Tomita,H Nakagami,K Yamamoto,A Moriguchi,Y Kaneda,J Higaki,T Ogihara, JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Vol. 16, p. S64-S64, 1998/06
0663 糖尿病内皮障害における肝細胞特異的因子(HGF)の役割 : 血管内皮細胞のアポトーシス抑制とそのメカニズム解明, 中神啓徳,森下竜一,林真一郎,松下英嗣,冨田奈留也,谷山義明,山本圭,守口篤,檜垣實男,荻原俊男, Japanese circulation journal, 社団法人日本循環器学会, Vol. 62, p. 271-271, 1998/02/28
1064 Senescent Cell-Dervid Inhibitor(sdi-1)遺伝子による血管平滑筋細胞増殖抑制及びアポトーシス誘導機構の解明, 松下英嗣,森下竜一,谷山義明,木田岩男,富田奈留也,中村成史,中神啓徳,林真一郎,山本圭,守口篤,檜垣實男,荻原俊男, Japanese circulation journal, 社団法人日本循環器学会, Vol. 62, p. 371-371, 1998/02/28
P824 がん抑制遺伝子p53喪失によるヒト血管平滑筋細胞の増殖促進とVEGF(Vascular Endothelial Growth Factor)産生増加 : p53のacure coronary syndromeへの関与の可能性, 松下英嗣,森下竜一,青木元邦,林真一郎,冨田奈留也,中神啓徳,谷山義明,守口篤,檜垣實男,荻原俊男, Japanese circulation journal, 社団法人日本循環器学会, Vol. 62, p. 592-592, 1998/02/28
0988 心肥大への局所アンジオテンシン変換酵素(ACE)の関与の直接証明 : ラット心臓へのヒトACE遺伝子の導入による心肥大モデル作成, 青木元邦,森下竜一,松下英嗣,谷山義明,中神啓徳,林真一郎,冨田奈留也,守口篤,檜垣實男,荻原俊男,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 62, p. 352-352, 1998/02/28
1011 NFKBデコイ遺伝子導入による心筋梗塞治療の可能性 : 低酸素状態における内皮細胞死に対する抑制作用およびその機序の検討, 松下英嗣,森下竜一,林真一郎,谷山義明,冨田奈留也,中村成史,中神啓徳,山本圭,守口篤,檜垣實男,萩原俊男,金田安史, Japanese circulation journal, 社団法人日本循環器学会, Vol. 62, p. 358-358, 1998/02/28

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疾患の要因となる生体内タンパク質を標的とするコンジュゲートワクチン, 中神啓徳,森下竜一,天満昭子, 特許第6941321号, WO2017-164409, JP2017012187, 出願日:2017/03/24, 登録日:2021/09/08
炎症性皮膚疾患の予防又は治療剤, 島村宗尚,中神啓徳,池田裕香,森下竜一,郡山弘, 特許第6710416号, WO2018-084311, JP2017040115, 出願日:2017/11/07, 登録日:2020/05/29
アポリポプロテイン(a)の特異的エピトープを含むDNAワクチン, 久徳真梨子,中神啓徳,郡山弘,中神太志,森下竜一, 特許第6001974号, 特願2012-208796, 出願日:2012/09/21, 登録日:2016/09/09
薬剤溶出型カテーテル及びその製造方法, 森下竜一,中神啓徳,三宅隆,三田村真,中島弘明,松田浩明,水津尚央,河野義史,▲高▼木邦彦,辻本広行,塚田雄亮,原香織,板東容平, 特許第5591103号, WO2009-113605, 特願2010-502866, 出願日:2009/03/12, 登録日:2014/08/08
ワクチン組成物, 佐藤靖史,中神啓徳,冨岡英樹, WO2019-045025, JP2018032276, 出願日:2018/08/30
S100A9を標的とする免疫原性組成物, 島村宗尚,河野友裕,中神啓徳,森下竜一,望月秀樹,天満昭子,江原貴子, WO2018-155457, JP2018006082, 出願日:2018/02/20
ペプチドワクチン及び当該ペプチドに対する特異抗体を有効成分とする医薬, 横田陽匡,中神啓徳,吉田晃敏, 特願2017-051014, 出願日:2017/03/16

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Nakagami Hironori

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