Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model

Tomonori Shibata, Konami Nagano, Morio Ueyama, Kensuke Ninomiya, Tetsuro Hirose, Yoshitaka Nagai, Kinya Ishikawa, Gota Kawai, Kazuhiko Nakatani

Nature Communications　Vol. 12　No. 1　p. 236-236　2020/12　Research paper (scientific journal)

Lnc RNA ‐dependent nuclear stress bodies promote intron retention through SR protein phosphorylation

Kensuke Ninomiya, Shungo Adachi, Tohru Natsume, Junichi Iwakiri, Goro Terai, Kiyoshi Asai, Tetsuro Hirose

The EMBO Journal　Vol. 39　No. 3　2020/02/03　Research paper (scientific journal)

Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor

Kensuke Ninomiya, Naoyuki Kataoka, Masatoshi Hagiwara

JOURNAL OF CELL BIOLOGY　Vol. 195　No. 1　p. 27-40　2011/10　Research paper (scientific journal)

Architectural RNAs: blueprints for functional membraneless organelle assembly

Tetsuro Hirose, Naoko Fujiwara, Kensuke Ninomiya, Tetsuya Yamamoto, Shinichi Nakagawa, Tomohiro Yamazaki

Trends in Genetics　2025/06　Research paper (scientific journal)

Biophysical aspect of assembly and regulation of nuclear bodies scaffolded by architectural RNA

Tetsuya Yamamoto, Tomohiro Yamazaki, Kensuke Ninomiya, Shinichi Nakagawa, Tetsuro Hirose

Journal of Molecular Biology　p. 169016-169016　2025/02　Research paper (scientific journal)

Nascent ribosomal RNA act as surfactant that suppresses growth of fibrillar centers in nucleolus

Tetsuya Yamamoto, Tomohiro Yamazaki, Kensuke Ninomiya, Tetsuro Hirose

Communications Biology　Vol. 6　No. 1　2023/11/07　Research paper (scientific journal)

Short Tandem Repeat-Enriched Architectural RNAs in Nuclear Bodies: Functions and Associated Diseases.

Kensuke Ninomiya, Tetsuro Hirose

Non-coding RNA　Vol. 6　No. 1　2020/02/20

Two distinct nuclear stress bodies containing different sets of RNA-binding proteins are formed with HSATIII architectural noncoding RNAs upon thermal stress exposure.

Mahmoud Khamis Aly, Kensuke Ninomiya, Shungo Adachi, Tohru Natsume, Tetsuro Hirose

Biochemical and biophysical research communications　Vol. 516　No. 2　p. 419-423　2019/08/20　Research paper (scientific journal)

Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain.

Akihide Takeuchi, Kei Iida, Toshiaki Tsubota, Motoyasu Hosokawa, Masatsugu Denawa, J B Brown, Kensuke Ninomiya, Mikako Ito, Hiroshi Kimura, Takaya Abe, Hiroshi Kiyonari, Kinji Ohno, Masatoshi Hagiwara

Cell reports　Vol. 23　No. 5　p. 1326-1341　2018/05/01　Research paper (scientific journal)

RBM24 promotes U1 snRNP recognition of the mutated 5 ' splice site in the IKBKAP gene of familial dysautonomia

Kenji Ohe, Mayumi Yoshida, Akiko Nakano-Kobayashi, Motoyasu Hosokawa, Yukiya Sako, Maki Sakuma, Yukiko Okuno, Tomomi Usui, Kensuke Ninomiya, Takayuki Nojima, Naoyuki Kataoka, Masatoshi Hagiwara

RNA　Vol. 23　No. 9　p. 1393-1403　2017/09　Research paper (scientific journal)

Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy

Yukiya Sako, Kensuke Ninomiya, Yukiko Okuno, Masayasu Toyomoto, Atsushi Nishida, Yuka Koike, Kenji Ohe, Isao Kii, Suguru Yoshida, Naohiro Hashimoto, Takamitsu Hosoya, Masafumi Matsuo, Masatoshi Hagiwara

SCIENTIFIC REPORTS　Vol. 7　2017/05　Research paper (scientific journal)

Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain

Tetsuya Ishimoto, Kensuke Ninomiya, Ran Inoue, Masato Koike, Yasuo Uchiyama, Hisashi Mori

GLIA　Vol. 65　No. 5　p. 727-739　2017/05　Research paper (scientific journal)

Transport Granules Bound with Nuclear Cap Binding Protein and Exon Junction Complex Are Associated with Microtubules and Spatially Separated from eIF4E Granules and P Bodies in Human Neuronal Processes.

Dan O Wang, Kensuke Ninomiya, Chihiro Mori, Ayako Koyama, Martine Haan, Makoto Kitabatake, Masatoshi Hagiwara, Kazuhiro Chida, Shin-Ichiro Takahashi, Mutsuhito Ohno, Naoyuki Kataoka

Frontiers in molecular biosciences　Vol. 4　p. 93-93　2017　Research paper (scientific journal)

Dendritic transport element of human arc mRNA confers RNA degradation activity in a translation-dependent manner

Kensuke Ninomiya, Mutsuhito Ohno, Naoyuki Kataoka

GENES TO CELLS　Vol. 21　No. 11　p. 1263-1269　2016/11　Research paper (scientific journal)

Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice

Satoshi Morooka, Mitsuteru Hoshina, Isao Kii, Takayoshi Okabe, Hirotatsu Kojima, Naoko Inoue, Yukiko Okuno, Masatsugu Denawa, Suguru Yoshida, Junichi Fukuhara, Kensuke Ninomiya, Teikichi Ikura, Toshio Furuya, Tetsuo Nagano, Kousuke Noda, Susumu Ishida, Takamitsu Hosoya, Nobutoshi Ito, Nagahisa Yoshimura, Masatoshi Hagiwara

MOLECULAR PHARMACOLOGY　Vol. 88　No. 2　p. 316-325　2015/08　Research paper (scientific journal)

Subcellular localization of PMES-2 proteins regulated by their two cytoskeleton-associated domains

K Ninomiya, T Ishimoto, T Taguchi

CELLULAR AND MOLECULAR NEUROBIOLOGY　Vol. 25　No. 5　p. 899-911　2005/08　Research paper (scientific journal)

Cloning and characterization of a novel synaptosome-enriched mRNA that encodes 31 kDa protein

T Ishimoto, K Ninomiya, K Miyaji, A Uyeda, M Kasai, T Taguchi

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION　Vol. 1579　No. 2-3　p. 189-195　2002/12　Research paper (scientific journal)