Preparation and Characterization of Acrylic and Methacrylic Phospholipid-Mimetic Polymer Hydrogels and Their Applications in Optical Tissue Clearing

Nanako Dei, Kazuhiko Ishihara, Akikazu Matsumoto, Chie Kojima

Polymers　Vol. 16　No. 2　2024/01/15　Research paper (scientific journal)

Biomimetic-Engineered Silicone Hydrogel Contact Lens Materials

Kazuhiko Ishihara, Xinfeng Shi, Kyoko Fukazawa, Tetsuji Yamaoka, George Yao, James Yuliang Wu

ACS Applied Bio Materials　Vol. 6　No. 9　p. 3600-3616　2023/08/24　Research paper (scientific journal)

Preparation of Water-Soluble Polyion Complex (PIC) Micelles with Random Copolymers Containing Pendant Quaternary Ammonium and Sulfonate Groups

Shukanta Bhowmik, Thu Thao Pham, Rintaro Takahashi, Dongwook Kim, Hideki Matsuoka, Kazuhiko Ishihara, Shin-ichi Yusa

Langmuir　Vol. 39　No. 23　p. 8120-8129　2023/05/26　Research paper (scientific journal)

Bioinspired antifouling and antibacterial polymer coating with intrinsic self-healing property

Anika Benozir Asha, Artjima Ounkaew, Yi-Yang Peng, Mohammad Reza Gholipour, Kazuhiko Ishihara, Yang Liu, Ravin Narain

Biomaterials Science　Vol. 11　No. 1　p. 128-139　2023/01　Research paper (scientific journal)

Biomimetic materials based on zwitterionic polymers toward human-friendly medical devices

Kazuhiko Ishihara

Science and Technology of Advanced Materials　Vol. 23　No. 1　p. 498-524　2022/12/31　Research paper (scientific journal)

Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions

Haruna Suzuki, Anna Adler, Tianwei Huang, Akiko Kuramochi, Yoshiro Ohba, Yuya Sato, Naoko Nakamura, Vivek Anand Manivel, Kristina Nilsson-Ekdahl, Bo Nilsson, Kazuhiko Ishihara, Yuji Teramura

Science and Technology of Advanced Materials　Vol. 23　No. 1　p. 845-857　2022/11/15　Research paper (scientific journal)

Improvement of Oral Absorption of Poorly Water-Soluble Drugs by Solid Dispersions with Amphiphilic Phospholipid Polymer

Kensuke Yoshie, Kazuhiko Ishihara

Journal of Pharmaceutical Sciences　Vol. 111　No. 11　p. 3141-3148　2022/11　Research paper (scientific journal)

Mechanical detection of interactions between proteins related to intermediate filament and transcriptional regulation in living cells

Ayana Yamagishi, Mei Mizusawa, Koki Uchida, Masumi Iijima, Shun’ichi Kuroda, Kyoko Fukazawa, Kazuhiko Ishihara, Chikashi Nakamura

Biosensors and Bioelectronics　Vol. 216　p. 114603-114603　2022/08　Research paper (scientific journal)

Preparation of Biocompatible Poly(2-(methacryloyloxy)ethyl phosphorylcholine) Hollow Particles Using Silica Particles as a Template

Sayaka Fujii, Shohei Kozuka, Kaito Yokota, Kazuhiko Ishihara, Shin-ichi Yusa

Langmuir　Vol. 38　No. 18　p. 5812-5819　2022/05/10　Research paper (scientific journal)

Formation of Water-Soluble Complexes from Fullerene with Biocompatible Block Copolymers Bearing Pendant Glucose and Phosphorylcholine

Kohei Kitano, Kazuhiko Ishihara, Shin-ichi Yusa

Langmuir　Vol. 38　No. 18　p. 5744-5751　2022/05/10　Research paper (scientific journal)

pH-Responsive Association Behavior of Biocompatible Random Copolymers Containing Pendent Phosphorylcholine and Fatty Acid

Shin-ichi Yusa, Daishiro Oka, Yasuhiko Iwasaki, Kazuhiko Ishihara

Langmuir　Vol. 38　No. 17　p. 5119-5127　2022/05/03　Research paper (scientific journal)

Cell-membrane-inspired polymers for constructing biointerfaces with efficient molecular recognition

Kazuhiko Ishihara, Kyoko Fukazawa

Journal of Materials Chemistry B　Vol. 10　No. 18　p. 3349-3419　2022/05　Research paper (scientific journal)

Dopamine Assisted Self-Cleaning, Antifouling, and Antibacterial Coating via Dynamic Covalent Interactions

Anika Benozir Asha, Yi-Yang Peng, Qiuli Cheng, Kazuhiko Ishihara, Yang Liu, Ravin Narain

ACS Applied Materials & Interfaces　2022/02/11　Research paper (scientific journal)

Separated Micelles Formation of pH-Responsive Random and Block Copolymers Containing Phosphorylcholine Groups

Thi Lien Nguyen, Kazuhiko Ishihara, Shin Ichi Yusa

Polymers　Vol. 14　No. 3　2022/02/01　Research paper (scientific journal)

Transepithelial delivery of insulin conjugated with phospholipid-mimicking polymers via biomembrane fusion-mediated transcellular pathways

Hiroaki Hatano, Fanlu Meng, Momoko Sakata, Akira Matsumoto, Kazuhiko Ishihara, Yuji Miyahara, Tatsuro Goda

Acta Biomaterialia　Vol. 140　p. 674-685　2022/02　Research paper (scientific journal)

pH-Induced formation of separated micelles in a mixture of random and block copolymers having phosphorylcholine groups in aqueous solution

Lien Nguyen, Kazuhiko Ishihara, Shin-Ichi Yusa

Polymers　Vol. 14　2022/02　Research paper (scientific journal)

Photoinduced immobilization of 2-methacryloyloxyethyl phosphorylcholine polymers with different molecular architectures on a poly(ether ether ketone) surface

Kyoko Fukazawa, Mingwei Mu, Sheng-Han Chen, Kazuhiko Ishihara

Journal of Materials Chemistry B　Vol. 10　No. 14　p. 2699-2707　2022　Research paper (scientific journal)

Induction of mesenchymal stem cell differentiation by co-culturing with mature cells in double-layered 2-methacryloyloxyethyl phosphorylcholine polymer hydrogel matrices

Kazuhiko Ishihara, Miu Kaneyasu, Kyoko Fukazawa, Ren Zhang, Yuji Teramura

Journal of Materials Chemistry B　Vol. 10　No. 14　p. 2561-2569　2022　Research paper (scientific journal)

Preparation of a thermo-responsive drug carrier consisting of a biocompatible triblock copolymer and fullerene

Kohei Kitano, Kazuhiko Ishihara, Shin-ichi Yusa

Journal of Materials Chemistry B　Vol. 10　No. 14　p. 2551-2560　2022　Research paper (scientific journal)

Efficacy of hydrated phospholipid polymer interfaces between all‐polymer bearings for total hip arthroplasty

Masayuki Kyomoto, Toru Moro, Shihori Yamane, Kenichi Watanabe, Masami Hashimoto, Sakae Tanaka, Kazuhiko Ishihara

Journal of Biomedical Materials Research Part B: Applied Biomaterials　Vol. 110　No. 1　p. 89-102　2022/01　Research paper (scientific journal)

Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins

Anna Adler, Yuuki Inoue, Kristina N. Ekdahl, Teruhiko Baba, Kazuhiko Ishihara, Bo Nilsson, Yuji Teramura

Journal of Materials Chemistry B　Vol. 10　No. 14　p. 2512-2522　2022　Research paper (scientific journal)

Intravenous Administration of Dehydroxymethylepoxyquinomicin With Polymer Enhances the Inhibition of Pancreatic Carcinoma Growth in Mice

Hiroto Fujisaki, Yutaka Nakano, Sachiko Matsuda, Keiichi Suzuki, Osamu Itano, Masayuki Tanaka, Tomohiro Konno, Kazuhiko Ishihara, Keiko Ohno, Satoshi Kishino, Kazuo Umezawa, Yuko Kitagawa

Anticancer Research　Vol. 41　No. 12　p. 6003-6012　2021/12　Research paper (scientific journal)

Stabilization of Lipid Lamellar Bilayer Structure of Stratum Corneum Modulated by Poly (2-methacryloyloxyethyl phosphorylcholine) in Relation to Skin Hydration and Skin Protection

Ae-Ri Cho Lee, Heekyung Moon, Kazuhiko Ishihara

Tissue Engineering and Regenerative Medicine　Vol. 18　No. 6　p. 953-962　2021/12　Research paper (scientific journal)

Nanoscaled Morphology and Mechanical Properties of a Biomimetic Polymer Surface on a Silicone Hydrogel Contact Lens

Xinfeng Shi, Vinay Sharma, David Cantu-Crouch, George Yao, Kyoko Fukazawa, Kazuhiko Ishihara, James Yuliang Wu

Langmuir　Vol. 37　No. 47　p. 13961-13967　2021/11/30　Research paper (scientific journal)

Preparation of Magnetic Hydrogel Microparticles with Cationic Surfaces and Their Cell-Assembling Performance

Kazuhiko Ishihara, Yusuke Narita, Yuji Teramura, Kyoko Fukazawa

ACS Biomaterials Science & Engineering　Vol. 7　No. 11　p. 5107-5117　2021/11/08　Research paper (scientific journal)

Impact of REDV peptide density and its linker structure on the capture, movement, and adhesion of flowing endothelial progenitor cells in microfluidic devices

Atsushi Mahara, Kazuki Kitagawa, Akihisa Otaka, Takahiko Nakaoki, Kazuhiko Ishihara, Tetsuji Yamaoka

Materials Science and Engineering: C　Vol. 129　p. 112381-112381　2021/10　Research paper (scientific journal)

Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipids and their characterization and surface properties of modified liposomes for protein interactions

Anna Adler, Yuuki Inoue, Yuya Sato, Kazuhiko Ishihara, Kristina N. Ekdahl, Bo Nilsson, Yuji Teramura

Biomaterials Science　Vol. 9　No. 17　p. 5854-5867　2021/09　Research paper (scientific journal)

Facile preparation of water-soluble multiwalled carbon nanotubes bearing phosphorylcholine groups for heat generation under near-infrared irradiation

Thi Lien Nguyen, Madoka Takai, Kazuhiko Ishihara, Keigo Oyama, Syuji Fujii, Shin-ichi Yusa

Polymer Journal　Vol. 53　No. 9　p. 1001-1009　2021/09/01　Research paper (scientific journal)

Induction of Spontaneous Liposome Adsorption by Exogenous Surface Modification with Cell-Penetrating Peptide-Conjugated Lipids

Yuya Sato, Kenta Asawa, Tianwei Huang, Makoto Noiri, Naoko Nakamura, Kristina N. Ekdahl, Bo Nilsson, Kazuhiko Ishihara, Yuji Teramura

Langmuir　Vol. 37　No. 32　p. 9711-9723　2021/08/17　Research paper (scientific journal)

Chemical Structural Effects of Amphipathic and Water-soluble Phospholipid Polymers on Formulation of Solid Dispersions

Kensuke Yoshie, Shuichi Yada, Shuichi Ando, Kazuhiko Ishihara

Journal of Pharmaceutical Sciences　Vol. 110　No. 8　p. 2966-2973　2021/08　Research paper (scientific journal)

Water-soluble polymer micelles formed from amphiphilic diblock copolymers bearing pendant phosphorylcholine and methoxyethyl groups

Alisa Tsuji, Thi Lien Nguyen, Yoko Mizoue, Kazuhiko Ishihara, Shin-ichi Yusa

Polymer Journal　Vol. 53　No. 7　p. 805-814　2021/07　Research paper (scientific journal)

Anticancer Activity of Cell-Penetrating Redox Phospholipid Polymers

Masahiro Kaneko, Masahito Ishikawa, Shuji Nakanishi, Kazuhiko Ishihara

ACS Macro Letters　Vol. 10　No. 7　p. 926-932　2021/06/28　Research paper (scientific journal)

Exogenous Cell Surface Modification with Cell Penetrating Peptide-Conjugated Lipids Causes Spontaneous Cell Adhesion

Makoto Noiri, Yuya Goto, Yuya Sato, Naoko Nakamura, Kazuhiko Ishihara, Yuji Teramura

ACS Applied Bio Materials　Vol. 4　No. 5　p. 4598-4606　2021/05/17　Research paper (scientific journal)

Effects of Initially Adsorbed Proteins on Substrate Surfaces during Multilayer Heterogeneous Protein Adsorption

Atsunori Sonoi, Ippei Furikado, Kazuhiko Ishihara

Langmuir　Vol. 37　No. 13　p. 3897-3902　2021/04/06　Research paper (scientific journal)

Adhesion of Flk1-expressing cells under shear flow in phospholipid polymer-coated immunoaffinity channels

Akihisa Otaka, Atsushi Mahara, Kazuhiko Ishihara, Tetsuji Yamaoka

Journal of Micromechanics and Microengineering　Vol. 31　No. 4　p. 045012-045012　2021/04/01　Research paper (scientific journal)

Control of Cell‐Substrate Binding Related to Cell Proliferation Cycle Status Using a Cytocompatible Phospholipid Polymer Bearing Phenylboronic Acid Groups

Kazuhiko Ishihara, Masashi Abe, Kyoko Fukazawa, Tomohiro Konno

Macromolecular Bioscience　Vol. 21　No. 4　p. 2000341-2000341　2021/04　Research paper (scientific journal)

Antifouling Silicone Hydrogel Contact Lenses with a Bioinspired 2-Methacryloyloxyethyl Phosphorylcholine Polymer Surface

Kazuhiko Ishihara, Kyoko Fukazawa, Vinay Sharma, Shuang Liang, Amanda Shows, Daniel Chuck Dunbar, Yang Zheng, Junhao Ge, Steve Zhang, Ye Hong, Xinfeng Shi, James Yuliang Wu

ACS Omega　Vol. 6　No. 10　p. 7058-7067　2021/03/16　Research paper (scientific journal)

Effects of molecular architecture of photoreactive phospholipid polymer on adsorption and reaction on substrate surface under aqueous condition

Kazuhiko Ishihara, Kohei Suzuki, Yuuki Inoue, Kyoko Fukazawa

Journal of Biomaterials Science, Polymer Edition　Vol. 32　No. 4　p. 419-437　2021/03/04　Research paper (scientific journal)

Cell Surface Functionalization with Heparin‐Conjugated Lipid to Suppress Blood Activation

Kenta Asawa, Kazuhiko Ishihara, Kristina N. Ekdahl, Bo Nilsson, Yuji Teramura

Advanced Functional Materials　Vol. 31　No. 11　p. 2008167-2008167　2021/03　Research paper (scientific journal)

Direct photoreactive immobilization of water-soluble phospholipid polymers on substrates in an aqueous environment

Kyoko Fukazawa, Kazushi Tsuji, Yuuki Inoue, Kazuhiko Ishihara

Colloids and Surfaces B: Biointerfaces　Vol. 199　p. 111507-111507　2021/03　Research paper (scientific journal)

Surface characterization of a silicone hydrogel contact lens having bioinspired 2-methacryloyloxyethyl phosphorylcholine polymer layer in hydrated state

Xinfeng Shi, David Cantu-Crouch, Vinay Sharma, John Pruitt, George Yao, Kyoko Fukazawa, James Yuliang Wu, Kazuhiko Ishihara

Colloids and Surfaces B: Biointerfaces　Vol. 199　p. 111539-111539　2021/03　Research paper (scientific journal)

Biomimetic phospholipid polymers for suppressing adsorption of saliva proteins on dental hydroxyapatite substrate

Kazuhiko Ishihara, Yoichiro Kozaki, Yuuki Inoue, Kyoko Fukazawa

Journal of Applied Polymer Science　Vol. 138　No. 6　p. 49812-49812　2021/02/10　Research paper (scientific journal)

Zwitterionized Nanofibrous Poly(vinylidene fluoride) Membranes for Improving the Healing of Diabetic Wounds

Irish Valerie Maggay, Antoine Venault, Chi-Yao Fang, Cheng-Chen Yang, Chen-Hua Hsu, Chih-Yu Chou, Kazuhiko Ishihara, Yung Chang

ACS Biomaterials Science & Engineering　Vol. 7　No. 2　p. 562-576　2021/02/08　Research paper (scientific journal)

Functional coatings for lab-on-a-chip systems based on phospholipid polymers

Yan Xu, Madoka Takai, Kazuhiko Ishihara

Handbook of Modern Coating Technologies　p. 555-595　2021　Part of collection (book)

Thermo-Responsive Behavior of Mixed Aqueous Solution of Hydrophilic Polymer with Pendant Phosphorylcholine Group and Poly(Acrylic Acid).

Hirokazu Fukumoto, Kazuhiko Ishihara, Shin-Ichi Yusa

Polymers　Vol. 13　No. 1　2021/01/01　Research paper (scientific journal)

Effects of inner polarity and viscosity of amphiphilic phospholipid polymer aggregates on the solubility enhancement of poorly water-soluble drugs

Kensuke Yoshie, Shuichi Yada, Shuichi Ando, Kazuhiko Ishihara

Colloids and Surfaces B: Biointerfaces　Vol. 195　p. 111215-111215　2020/11　Research paper (scientific journal)

Antibacterial effect of nanometer‐size grafted layer of quaternary ammonium polymer on poly(ether ether ketone) substrate

Keiko Oai, Yuuki Inoue, Aiko Nakao, Kyoko Fukazawa, Kazuhiko Ishihara

Journal of Applied Polymer Science　Vol. 137　No. 37　p. 49088-49088　2020/10/05　Research paper (scientific journal)

Potential of Cell Surface Engineering with Biocompatible Polymers for Biomedical Applications

Yuji Teramura, Kristina Nilsson Ekdahl, Karin Fromell, Bo Nilsson, Kazuhiko Ishihara

LANGMUIR　Vol. 36　No. 41　p. 12088-12106　2020/10　Research paper (scientific journal)

2-Methacryloyloxyethyl Phosphorylcholine Polymer Coating Inhibits Bacterial Adhesion and Biofilm Formation on a Suture: An In Vitro and In Vivo Study

Taizo Kaneko, Taku Saito, Takeo Shobuike, Hiroshi Miyamoto, Junpei Matsuda, Kyoko Fukazawa, Kazuhiko Ishihara, Sakae Tanaka, Toru Moro

BioMed Research International　Vol. 2020　p. 1-8　2020/10/01　Research paper (scientific journal)

Effects of molecular interactions at various polymer brush surfaces on fibronectin adsorption induced cell adhesion

Kazuhiko Ishihara, Katsuya Mitera, Yuuki Inoue, Kyoko Fukazawa

Colloids and Surfaces B: Biointerfaces　Vol. 194　p. 111205-111205　2020/10　Research paper (scientific journal)

Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids

Akifumi Yoshihara, Sayumi Watanabe, Isha Goel, Kazuhiko Ishihara, Kristina N. Ekdahl, Bo Nilsson, Yuji Teramura

Biomaterials　Vol. 253　p. 120113-120113　2020/09　Research paper (scientific journal)

Synthesis of Amphiphilic Statistical Copolymers Bearing Methoxyethyl and Phosphorylcholine Groups and Their Self-Association Behavior in Water

Thi Lien Nguyen, Yuuki Kawata, Kazuhiko Ishihara, Shin-ichi Yusa

Polymers　Vol. 12　No. 8　p. 1808-1808　2020/08/12　Research paper (scientific journal)

Water-Soluble and Cytocompatible Phospholipid Polymers for Molecular Complexation to Enhance Biomolecule Transportation to Cells In Vitro

Kazuhiko Ishihara, Shohei Hachiya, Yuuki Inoue, Kyoko Fukazawa, Tomohiro Konno

Polymers　Vol. 12　No. 8　p. 1762-1762　2020/08/06　Research paper (scientific journal)

Combination of two antithrombogenic methodologies for preventing thrombus formation on a poly(ether ether ketone) substrate

Kazuhiko Ishihara, Satoshi Yanokuchi, Yuji Teramura, Kyoko Fukazawa

Colloids and Surfaces B: Biointerfaces　Vol. 192　2020/08　Research paper (scientific journal)

Redox‐Active Polymers Connecting Living Microbial Cells to an Extracellular Electrical Circuit

Masahiro Kaneko, Kazuhiko Ishihara, Shuji Nakanishi

Small　p. 2001849-2001849　2020/07/30　Research paper (scientific journal)

Interface of Phospholipid Polymer Grafting Layers to Analyze Functions of Immobilized Oligopeptides Involved in Cell Adhesion

Kazuhiko Ishihara, Misaki Ito, Kyoko Fukazawa, Yuuki Inoue

ACS Biomaterials Science & Engineering　Vol. 6　No. 7　p. 3984-3993　2020/07/13　Research paper (scientific journal)

Photoinduced self-initiated graft polymerization of methacrylate monomers on poly(ether ether ketone) substrates and surface parameters for controlling cell adhesion

Kazuhiko Ishihara, Satoshi Yanokuchi, Kyoko Fukazawa, Yuuki Inoue

Polymer Journal　Vol. 52　No. 7　p. 731-741　2020/07　Research paper (scientific journal)

Polymeric Nanocarriers with Controlled Chain Flexibility Boost mRNA Delivery In Vivo through Enhanced Structural Fastening.

Takuya Miyazaki, Satoshi Uchida, Satoru Nagatoishi, Kyoko Koji, Taehun Hong, Shigeto Fukushima, Kouhei Tsumoto, Kazuhiko Ishihara, Kazunori Kataoka, Horacio Cabral

Advanced Healthcare Materials　Vol. 9　No. 16　2020/06/25　Research paper (scientific journal)

Phospholipid Polymer Hydrogel Matrices with Dually Immobilized Cytokines for Accelerating Secretion of the Extracellular Matrix by Encapsulated Cells

Ren Zhang, Yuji Teramura, Kyoko Fukazawa, Kazuhiko Ishihara

Macromolecular Bioscience　p. 2000114-2000114　2020/06/22　Research paper (scientific journal)

Identification of Metal-Binding Peptides and Their Conjugation onto Nanoparticles of Superparamagnetic Iron Oxides and Liposomes

Tomonobu Kodama, Akifumi Yoshihara, Isha Goel, Masaki Sekino, Akihiro Kuwahata, Atsushi Yoshimori, Yuichi Murayama, Kazuhiko Ishihara, Kristina N. Ekdahl, Bo Nilsson, Yuji Teramura

ACS Applied Materials & Interfaces　Vol. 12　No. 22　p. 24623-24634　2020/06/03　Research paper (scientific journal)

Spontaneously and reversibly forming phospholipid polymer hydrogels as a matrix for cell engineering

Kazuhiko Ishihara, Haruka Oda, Tomohiro Konno

Biomaterials　Vol. 230　p. 119628-119628　2020/02　Research paper (scientific journal)

Singlet oxygen generation by sonication using a water-soluble fullerene (C<inf>60</inf>) complex: a potential application for sonodynamic therapy

Thi Lien Nguyen, Risa Katayama, Chie Kojima, Akikazu Matsumoto, Kazuhiko Ishihara, Shin ichi Yusa

Polymer Journal　Vol. 52　No. 12　p. 1387-1394　2020　Research paper (scientific journal)

Phospholipid-mimicking cell-penetrating polymers: principles and applications

Tatsuro Goda, Yuji Miyahara, Kazuhiko Ishihara

Journal of Materials Chemistry B　Vol. 8　No. 34　p. 7633-7641　2020　Research paper (scientific journal)

Formation of stable polydopamine layer on polytetrafluoroethylene substrate by hybrid process involved plasma treatment and spontaneous chemical reactions

Bohan Cheng, Yuuki Inoue, Kazuhiko Ishihara

Mater Today Commun　Vol. 22　No. 3　2020　Research paper (scientific journal)

Cell-Membrane Permeable Redox Phospholipid Polymers Induce Apoptosis in MDA-MB-231 Human Breast Cancer Cells

Kaneko, Masahiro, Ishikawa, Masahito, Ishihara, Kazuhiko, Nakanishi, Shuji

BIOMACROMOLECULES　Vol. 20　No. 12　p. 4447-4456　2019/12　Research paper (scientific journal)

Polyelectrolyte and Antipolyelectrolyte Effects for Dual Salt-Responsive Interpenetrating Network Hydrogels

Huang, Kang-Ting, Ishihara, Kazuhiko, Huang, Chun-Jen

BIOMACROMOLECULES　Vol. 20　No. 9　p. 3524-3534　2019/09　Research paper (scientific journal)

Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium

Noiri, Makoto, Asawa, Kenta, Okada, Naoya, Kodama, Tomonobu, Murayama, Yuichi, Inoue, Yuuki, Ishihara, Kazuhiko,, Kristina N, Nilsson, Bo, Teramura, Yuji

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A　Vol. 107　No. 8　p. 1779-1792　2019/08　Research paper (scientific journal)

Interpolymer association of amphiphilic diblock copolymers bearing pendant siloxane and phosphorylcholine groups

Kozuka, Shohei, Kuroda, Keita, Ishihara, Kazuhiko,, Shin-ichi

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY　Vol. 57　No. 14　p. 1500-1507　2019/07

Hybridization of a phospholipid polymer hydrogel with a natural extracellular matrix using active cell immobilization

Zhang, Ren, Inoue, Yuuki, Konno, Tomohiro, Ishihara, Kazuhiko

BIOMATERIALS SCIENCE　Vol. 7　No. 7　p. 2793-2802　2019/07　Research paper (scientific journal)

Translocation Mechanisms of Cell-Penetrating Polymers Identified by Induced Proton Dynamics

Tatsuro Goda, Yuki Imaizumi, Hiroaki Hatano, Akira Matsumoto, Kazuhiko Ishihara, Yuji Miyahara

Langmuir　Vol. 35　No. 24　p. 8167-8173　2019/05/16　Research paper (scientific journal)

Short-term evaluation of thromboresistance of a poly(ether ether ketone) (PEEK) mechanical heart valve with poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-grafted surface in a porcine aortic valve replacement model

Kambe, Yusuke, Mahara, Atsushi, Tanaka, Hiroshi, Kakinoki, Sachiro, Fukazawa, Kyoko, Liu, Yihua, Kyomoto, Masayuki, Minatoya, Kenji, Ishihara, Kazuhiko, Yamaoka, Tetsuji

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A　Vol. 107　No. 5　p. 1052-1063　2019/05　Research paper (scientific journal)

Toward Antibiofouling PVDF Membranes

Hsu, Chen-Hua, Venault, Antoine, Huang, Yu-Tzu, Wu, Bo-Wei, Chou, Chung-Jung, Ishihara, Kazuhiko, Chang, Yung

LANGMUIR　Vol. 35　No. 20　p. 6782-6792　2019/05

Validation of an MPC Polymer Coating to Attenuate Surface-Induced Crosstalk between the Complement and Coagulation Systems in Whole Blood in In Vitro and In Vivo Models

Asif, Sana, Asawa, Kenta, Inoue, Yuuki, Ishihara, Kazuhiko, Lindell, Bjorn, Holmgren, Robin, Nilsson, Bo, Ryden, Anneli, Jensen-Waern, Marianne, Teramura, Yuji, Ekdahl, Kristina N

MACROMOLECULAR BIOSCIENCE　Vol. 19　No. 5　2019/05　Research paper (scientific journal)

Synthesis and Properties of Upper Critical Solution Temperature Responsive Nanogels

Maho Ohshio, Kazuhiko Ishihara, Atsushi Maruyama, Naohiko Shimada, Shin-ichi Yusa

Langmuir　Vol. 35　No. 22　p. 7261-7267　2019/04/29　Research paper (scientific journal)

Phospholipid polymer multilayered hydrogels containing cells for cancer drug screening

Ishihara, K, Gao, B, Konno, T

Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium　Vol. 40　2019/04　Research paper (international conference proceedings)

Effects of a roughened femoral head and the locus of grafting on the wear resistance of the phospholipid polymer-grafted acetabular liner

Moro, Toru, Ishihara, Kazuhiko, Takatori, Yoshio, Tanaka, Sakae, Kyomoto, Masayuki, Hashimoto, Masami, Ishikura, Hisatoshi, Hidaka, Ryo, Tanaka, Takeyuki, Kawaguchi, Hiroshi, Nakamura, Kozo

ACTA BIOMATERIALIA　Vol. 86　p. 338-349　2019/03

Self-Association Behavior of Cell Membrane-Inspired Amphiphilic Random Copolymers in Water

Maho Ohshio, Kazuhiko Ishihara, Shin-ichi Yusa

Polymers　Vol. 11　No. 2　p. 327-327　2019/02/13　Research paper (scientific journal)

Zwitterionic Interfaces: Concepts and Emerging Applications Special Issue Preface

Jiang, Shaoyi, Ishihara, Kazuhiko, Iwasaki, Yasuhiko, Vancso, Julius

LANGMUIR　Vol. 35　No. 5　p. 1055-1055　2019/02　Research paper (scientific journal)

Rapid Mussel-Inspired Surface Zwitteration for Enhanced Antifouling and Antibacterial Properties

Asha, Anika Benozir, Chen, Yangjun, Zhang, Huixin, Ghaemi, Sina, Ishihara, Ishihara, Kazuhiko, Yang, Narain, Ravin

LANGMUIR　Vol. 35　No. 5　p. 1621-1630　2019/02

Hydrated Phospholipid Polymer Gel-Like Layer for Increased Durability of Orthopedic Bearing Surfaces

Kyomoto, Masayuki, Moro, Toru, Yamane, Shihori, Watanabe, Kenichi, Hashimoto, Masami, Tanaka, Sakae, Ishihara, Kazuhiko

LANGMUIR　Vol. 35　No. 5　p. 1954-1963　2019/02

Photoinduced Surface Zwitterionization for Antifouling of Porous Polymer Substrates

Chen, Sheng-Han, Fukazawa, Kyoko, Inoue, Yuuki, Ishihara, Kazuhiko

LANGMUIR　Vol. 35　No. 5　p. 1312-1319　2019/02　Research paper (scientific journal)

Determination of association constants between water-soluble phospholipid polymer bearing phenylboronic acid group and polyol compounds for reversible formation of three-dimensional networks

Oda, Haruka, Ishihara, Kazuhiko

REACTIVE & FUNCTIONAL POLYMERS　Vol. 135　p. 113-120　2019/02

Multi-layered PLLA-nanosheets loaded with FGF-2 induce robust bone regeneration with controlled release in critical-sized mouse femoral defects

Murahashi, Yasutaka, Yano, Fumiko, Nakamoto, Hideki, Maenohara, Yuji, Iba, Kousuke, Yamashita, Toshihiko, Tanaka, Sakae, Ishihara, Kazuhiko, Okamura, Yosuke, Moro, Toru, Saito, Taku

ACTA BIOMATERIALIA　Vol. 85　p. 172-179　2019/02　Research paper (scientific journal)

第61回 日本コンタクトレンズ学会 シンポジウム コンタクトレンズ素材としてのバイオマテリアルの創出

石原 一彦

日本コンタクトレンズ学会誌 = Journal of Japan Contact Lens Society　Vol. 61　No. 1　p. 2-8　2019

Surface functionalization of polytetrafluoroethylene substrate with hybrid processes comprising plasma treatment and chemical reactions

Cheng, Bohan, Inoue, Yuuki, Ishihara, Kazuhiko

COLLOIDS AND SURFACES B-BIOINTERFACES　Vol. 173　p. 77-84　2019/01　Research paper (scientific journal)

近赤外光照射による生体親和性ポリマーミセル中のシアニン色素の発熱挙動

白木 啓太, 石原 一彦, 遊佐 真一

高分子論文集　Vol. 76　No. 1　p. 52-60　2019

In situ surface modification on dental composite resin using 2-methacryloyloxyethyl phosphorylcholine polymer for controlling plaque formation

Jun Koyama, Kyoko Fukazawa, Kazuhiko Ishihara, Yoshiyuki Mori

Mater Sci Engineer C　Vol. 104　2019　Research paper (scientific journal)

Reaction of dopamine on plasma-treated polytetrafluoroethylene substrate to form a stable polydopamine layer

Bohan Cheng, Yuuki Inoue, Kazuhiko Ishihara

Colloid Surf B: Biointerfaces　2019　Research paper (scientific journal)

2-Methacryloyloxyethyl phosphorylcholine polymer can facilitate reduction of only bacterial quantity while maintaining bacterial homeostasis in denture plaque

Akihiro Tsukahara, Kenji Ikeya, Hirobumi Morisaki, Fuminori Iwasa, Yuuki Inoue, Miya Fukunishi, Nana Takahashi, Hirotaka Kuwata, Kazuhiko Ishihara, Kazuyoshi Baba

J Prosthetic Dent　2019　Research paper (scientific journal)

Bio-inspired immobilization of low-fouling phospholipid polymers via a simple dipping process: a comparative study of phenol, catechol and gallol as tethering groups

Bohan Cheng, Kazuhiko Ishihara, Hirotaka Ejima

Polym Chem　2019　Research paper (scientific journal)

Reducing fretting-initiated crevice corrosion in hip simulator tests using a zirconia-toughened alumina femoral head

Kyomoto, Masayuki, Shoyama, Yuichi, Saiga, Kenichi, Moro, Toru, Ishihara, Kazuhiko

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS　Vol. 106　No. 8　p. 2815-2826　2018/11

Reliable surface modification of dental plastic substrates to reduce biofouling with a photoreactive phospholipid polymer

Ishihara, Kazuhiko, Fukazawa, Kyoko, Inoue, Yuuki, Koyama, Jun, Mori, Yoshiyuki, Kinoshita, Toru, Hiranuma, Katsumi, Yasuda, Noboru

JOURNAL OF APPLIED POLYMER SCIENCE　Vol. 135　No. 30　2018/08　Research paper (scientific journal)

Bioinspired Self-Healing Hydrogel Based on Benzoxaborole-Catechol Dynamic Covalent Chemistry for 3D Cell Encapsulation

Chen, Yangjun, Diaz-Dussan, Diana, Wu, Di, Wang, Wenda, Peng, Yi-Yang, Asha, Anika Benozir, Hall, Dennis G, Ishihara, Kazuhiko, Narain, Ravin

ACS MACRO LETTERS　Vol. 7　No. 8　p. 904-908　2018/08

A surface graft polymerization process on chemically stable medical ePTFE for suppressing platelet adhesion and activation

Liu, Yihua, Munisso, Maria Chiara, Mahara, Atsushi, Kambe, Yusuke, Fukazawa, Kyoko, Ishihara, Kazuhiko, Yamaoka, Tetsuji

BIOMATERIALS SCIENCE　Vol. 6　No. 7　p. 1908-1915　2018/07　Research paper (scientific journal)

pH-Responsive Polyion Complex Vesicle with Polyphosphobetaine Shells

Yuki Ohara, Keita Nakai, Sana Ahmed, Kazuaki Matsumura, Kazuhiko Ishihara, Shin-ichi Yusa

Langmuir　Vol. 35　No. 5　p. 1249-1256　2018/06/25　Research paper (scientific journal)

Initial Cell Adhesion onto a Phospholipid Polymer Brush Surface Modified with a Terminal Cell Adhesion Peptide

Inoue, Yuuki, Onodera, Yuya, Ishihara, Kazuhiko

ACS APPLIED MATERIALS & INTERFACES　Vol. 10　No. 17　p. 15250-15257　2018/05　Research paper (scientific journal)

Polymer coating glass to improve the protein antifouling effect

Honda, Tomoko, Nakao, Aiko, Ishihara, Kazuhiko, Higaki, Yuji, Higaki, Keiko, Takahara, Atsushi, Iwasaki, Yasuhiko, Yusa, Shin-ichi

POLYMER JOURNAL　Vol. 50　No. 5　p. 381-388　2018/05　Research paper (scientific journal)

Call for Papers for Zwitterionic Interfaces: Concepts and Emerging Applications

Jiang, Shaoyi, Ishihara, Kazuhiko, Iwasaki, Yasuhiko, Vancso, Julius, MacLaughlin, Christina

LANGMUIR　Vol. 34　No. 11　p. 3375-3375　2018/03　Research paper (scientific journal)

Zwitterionic bi-continuous membranes from a phosphobetaine copolymer/poly(vinylidene fluoride) blend via VIPS for biofouling mitigation

Venault, Antoine, Hsu, Chen-Hua, Ishihara, Kazuhiko, Chang, Yung

JOURNAL OF MEMBRANE SCIENCE　Vol. 550　p. 377-388　2018/03　Research paper (scientific journal)

A phospholipid polymer graft layer affords high resistance for wear and oxidation under load bearing conditions

Kyomoto, Masayuki, Moro, Toru, Yamane, Shihori, Watanabe, Kenichi, Hashimoto, Masami, Tanaka, Sakae, Ishihara, Kazuhiko

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS　Vol. 79　p. 203-212　2018/03　Research paper (scientific journal)

Inhibition of denture plaque deposition on complete dentures by 2-methacryloyloxyethyl phosphorylcholine polymer coating: A clinical study

Ikeya, Kenji, Iwasa, Fuminori, Inoue, Yuuki, Fukunishi, Miya, Takahashi, Nana, Ishihara, Kazuhiko, Baba, Kazuyoshi

JOURNAL OF PROSTHETIC DENTISTRY　Vol. 119　No. 1　p. 67-74　2018/01　Research paper (scientific journal)

Wear resistance of poly(2-methacryloyloxyethyl phosphorylcholine)-grafted carbon fiber reinforced poly(ether ether ketone) liners against metal and ceramic femoral heads

Shihori Yamane, Masayuki Kyomoto, Toru Moro, Masami Hashimoto, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara

J Biomed Mater Res B　Vol. 106B　No. 3　p. 1028-1037　2018　Research paper (scientific journal)

Spontaneous hydrogel formation through hydrophobic interactions in an ABA-type block copolymer composed of poly(2-methacryloyloxyethyl phosphorylcholine) and poly(n-butyl methacrylate) segments

Mingwei Mu, Tomohiro Konno, Kazuhiko Ishihara

MRS Advances　Vol. 3　No. 30　p. 1691-1696　2018　Research paper (scientific journal)

Synthesis of highly biocompatible and temperature responsive physical gels for cryopreservation and 3D cell culture

Masanori Nagao, Jayeeta Sengupta, Dlana Diaz, Adam Madeleine, Meng Wu, Jason Acker, Robert Ben, Kazuhiko Ishihara, Hongbo Zeng, Yoshiko Miura, Ravin Narain

ACS Applied Bio Materials　Vol. 1　No. 2　p. 356-366　2018　Research paper (scientific journal)

Heteromorphic polymer nanoparticles in response to rotational magnetic fields for stirring inside living cells

Kazuhiko Ishihara, Kensuke Yoshie, Yuuki Inoue

IOP Conf Series: Mater Sci Eng　Vol. 381　2018　Research paper (international conference proceedings)

Micropatterning of phospholipid hydrogel layer on the substrate for controlled cell immobilization

Ren Zhang, Yuuki Inoue, Tomohiro Konno, Kazuhiko Ishihara

IOP Conf Series: Mater Sci Eng　Vol. 381　2018　Research paper (international conference proceedings)

Preparation of polyelectrolyte brush layer modified magnetic particles for separation of proteins

Jianli Gong, Yuuki Inoue, Kazuhiko Ishihara

IOP Conf Series: Mater Sci Eng　Vol. 381　2018　Research paper (international conference proceedings)

Conversion of functional group on PTFE surface by argon plasma pre-treatment and polydopamine coating

Bohan Cheng, Yuuki Inoue, Kazuhiko Ishihara

IOP Conf Series: Mater Sci Eng　Vol. 381　2018　Research paper (international conference proceedings)

Molecular integration on phospholipid polymer-coated magnetic beads for gene expression analysis in cells

Ishihara, Kazuhiko, Fukuda, Yoshito, Konno, Tomohiro, Inoue, Yuuki

REACTIVE & FUNCTIONAL POLYMERS　Vol. 119　p. 125-133　2017/10　Research paper (scientific journal)

Solubilization of poorly water-soluble compounds using amphiphilic phospholipid polymers with different molecular architectures

Mu, Mingwei, Konno, Tomohiro, Inoue, Yuuki, Ishihara, Kazuhiko

COLLOIDS AND SURFACES B-BIOINTERFACES　Vol. 158　p. 249-256　2017/10　Research paper (scientific journal)

Water-soluble complex formation of fullerene and thermo-responsive diblock copolymer

Yano Junki, Ishihara Kazuhiko, Yusa Shin Ichi

Journal of Polymer Science, Part A: Polymer Chemistry　Vol. 55　No. 15　p. 2432-2439　2017/08/01　Research paper (scientific journal)

Introduction of functional groups to reactive ABA block-copolymers composed of poly(2-methacryloyloxyethyl phosphorylcholine) and poly(glycidyl methacrylate) for spontaneous hydrogel formation

Chantasirichot, Surasak, Inoue, Yuuki, Ishihara, Kazuhiko

POLYMER　Vol. 123　p. 100-106　2017/08　Research paper (scientific journal)

Effects of Material Thickness and Surface Modification of Cross-linked Polyethylene with Poly(2-Methacryloyloxyethyl Phosphorylcholine) on Its Deformation Behavior, Wear Resistance, and Durability Under Repetitive Impact-to-sliding Motion

Saiga Kenichi, Kyomoto Masayuki, Watanabe Kenichi, Taketomi Shuji, Kadono Yuho, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko, Moro Toru

Biotribology　Vol. 10　p. 35-41　2017/06/01　Research paper (scientific journal)

Complexes Covered with Phosphorylcholine Groups Prepared by Mixing Anionic Diblock Copolymers and Cationic Surfactants

Nakai Keita, Ishihara Kazuhiko, Yusa Shin Ichi

Langmuir　Vol. 33　No. 21　p. 5236-5244　2017/05/30　Research paper (scientific journal)

Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat

Yudasaka Masako, Yomogida Yohei, Zhang Minfang, Tanaka Takeshi, Nakahara Masako, Kobayashi Norihiko, Okamatsu-Ogura Yuko, Machida Ken, Ishihara Kazuhiko, Saeki Kumiko, Kataura Hiromichi

Scientific Reports　Vol. 7　2017/03/20　Research paper (scientific journal)

Label-Free Separation of Induced Pluripotent Stem Cells with Anti-SSEA-1 Antibody Immobilized Microfluidic Channel

Otaka Akihisa, Kitagawa Kazuki, Nakaoki Takahiko, Hirata Mitsuhi, Fukazawa Kyoko, Ishihara Kazuhiko, Mahara Atsushi, Yamaoka Tetsuji

Langmuir　Vol. 33　No. 6　p. 1576-1582　2017/02/14　Research paper (scientific journal)

A hydrated phospholipid polymer-grafted layer prevents lipid-related oxidative degradation of cross-linked polyethylene

Kyomoto Masayuki, Moro Toru, Yamane Shihori, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko

Biomaterials　Vol. 112　p. 122-132　2017/01/01　Research paper (scientific journal)

A Polymethyl Methacrylate-Based Acrylic Dental Resin Surface Bound with a Photoreactive Polymer Inhibits Accumulation of Bacterial Plaque

Fukunishi, Miya, Inoue, Yuuki, Morisaki, Hirobumi, Kuwata, Hirotaka, Ishihara, Kazuhiko, Baba, Kazuyoshi

INTERNATIONAL JOURNAL OF PROSTHODONTICS　Vol. 30　No. 6　p. 533-540　2017/01　Research paper (scientific journal)

Reduced Blood Cell Adhesion on Polypropylene Substrates through a Simple Surface Zwitterionization

Chen, Sheng-Han, Chang, Yung, Ishihara, Kazuhiko

LANGMUIR　Vol. 33　No. 2　p. 611-621　2017/01　Research paper (scientific journal)

The effects of presence of a backside screw hole on biotribological behavior of phospholipid polymer-grafted crosslinked polyethylene

Watanabe Kenichi, Moro Toru, Kyomoto Masayuki, Saiga Kenichi, Taketomi Shuji, Kadono Yuho, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part B Applied Biomaterials　Vol. 106　No. 2　p. 610-618　2017　Research paper (scientific journal)

Polyion Complex Vesicles with Solvated Phosphobetaine Shells Formed from Oppositely Charged Diblock Copolymers

Nakai Keita, Ishihara Kazuhiko, Kappl Michael, Fujii Syuji, Nakamura Yoshinobu, Yusa Shin ichi

Polymers　Vol. 9　No. 2　2017　Research paper (scientific journal)

Wear resistance of poly(2-methacryloyloxyethyl phosphorylcholine)-grafted carbon fiber reinforced poly(ether ether ketone) liners against metal and ceramic femoral heads

Yamane Shihori, Kyomoto Masayuki, Moro Toru, Hashimoto Masami, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part B Applied Biomaterials　Vol. 106　No. 3　p. 1028-1037　2017　Research paper (scientific journal)

Preparation of giant polyion complex vesicles (G-PICsomes) with polyphosphobetaine shells composed of oppositely charged diblock copolymers

Nakai Keita, Ishihara Kazuhiko, Yusa Shin Ichi

Chemistry Letters　Vol. 46　No. 6　p. 824-827　2017　Research paper (scientific journal)

Inhibition of denture plaque deposition on complete dentures by 2-methacryloyloxyethyl phosphorylcholine polymer coating

Ikeya Kenji, Iwasa Fuminori, Inoue Yuuki, Fukunishi Miya, Takahashi Nana, Ishihara Kazuhiko, Baba Kazuyoshi

Journal of Prosthetic Dentistry　Vol. 119　No. 1　p. 67-74　2017　Research paper (scientific journal)

The noninvasive treatment for sentinel lymph node metastasis by photodynamic therapy using phospholipid polymer as a nanotransporter of verteporfin

Shimada Kyosuke, Matsuda Sachiko, Jinno Hiromitsu, Kameyama Noriaki, Konno Tomohiro, Arai Tsunenori, Ishihara Kazuhiko, Kitagawa Yuko

BioMed Research International　Vol. 2017　2017　Research paper (scientific journal)

Simultaneous patterning of proteins and cells through bioconjugation with photoreactable phospholipid polymers

Seo, Ji-Hun, Ishihara, Kazuhiko

RSC ADVANCES　Vol. 7　No. 64　p. 40669-40672　2017　Research paper (scientific journal)

Clinical safety and wear resistance of the phospholipid polymer-grafted highly cross-linked polyethylene liner

Toru Moro, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara, Hiromi Oda, Yoon Taek Kim, Takashige Umeyama, Eisei Fukatani, Hideya Ito, Masayuki Kyomoto, Hirofumi Oshima, Takeyuki Tanaka, Hiroshi Kawaguchi, Kozo Nakamura

J Orthop Res　Vol. 35　No. 9　p. 2007-2016　2017　Research paper (scientific journal)

Effects of surface modification of cross-linked polyethylene with poly(2-methacryloyloxyethyl phosphorylcholine) on its wear resistance and durability under repetitive impact-to-sliding motion

Kenichi Saiga, Masayuki Kyomoto, Kenichi Watanabe, Shuji Taketomi, Yuho Kadono, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara, Toru Moro

Biotribology　Vol. 10　p. 35-41　2017　Research paper (scientific journal)

Sandwich-type PLLA-nanosheets loaded with BMP-2 induce bone regeneration in critical-sized mouse calvarial defects

Taku Saito, Kuo-Chin Huang, Fumiko?Yano, Yasutaka Murahashi, Shuta Takano, Yoshiaki Kitaura, Song Ho Chang, Kazuhito Soma, Steve Ueng, Sakae Tanaka, Kazuhiko Ishihara, Yosuke Okamura, Toru Moro

Acta Biomater　Vol. 59　p. 2017/12/20-20　2017　Research paper (scientific journal)

Preventive effects of a phospholipid polymer coating on PMMA on biofilm formation by oral streptococci

Shibata Yukie, Yamashita Yoshihisa, Tsuru Kanji, Ishihara Kazuhiko, Fukazawa Kyoko, Ishikawa Kunio

Applied Surface Science　Vol. 390　p. 602-607　2016/12/30　Research paper (scientific journal)

2-methacryloyloxyethyl phosphorylcholine polymer treatment of complete dentures to inhibit denture plaque deposition

Ikeya Kenji, Fukunishi Miya, Iwasa Fuminori, Inoue Yuuki, Ishihara Kazuhiko, Baba Kazuyoshi

Journal of Visualized Experiments　Vol. 2016　No. 118　2016/12/26　Research paper (scientific journal)

Movement of a Quantum Dot Covered with Cytocompatible and pH-Responsible Phospholipid Polymer Chains under a Cellular Environment

Liu Yihua, Oda Haruka, Inoue Yuuki, Ishihara Kazuhiko

Biomacromolecules　Vol. 17　No. 12　p. 3986-3994　2016/12/12　Research paper (scientific journal)

Focus on nanomedicine molecular science

Kazuhiko Ishihara, Nobuhiko Yui

Science and Technology of Advanced Materials　Vol. 17　No. 1　p. 244-244　2016/12/01　Research paper (scientific journal)

High efficiency penetration of antibody-immobilized nanoneedle thorough plasma membrane for in situ detection of cytoskeletal proteins in living cells

Kawamura R, Shimizu K, Matsumoto Y, Yamagishi A, Silberberg Y. R, Iijima M, Kuroda S, Fukazawa K, Ishihara K, Nakamura C

Journal of Nanobiotechnology　Vol. 14　No. 1　2016/11/03　Research paper (scientific journal)

Precise control of surface electrostatic forces on polymer brush layers with opposite charges for resistance to protein adsorption

Sakata Sho, Inoue Yuuki, Ishihara Kazuhiko

Biomaterials　Vol. 105　p. 102-108　2016/10/01　Research paper (scientific journal)

Water-soluble complex formation of fullerenes with a biocompatible polymer

Ohata Tetsuya, Ishihara Kazuhiko, Iwasaki Yasuhiko, Sangsuwan Arunee, Fujii Shota, Sakurai Kazuo, Ohara Yuki, Yusa Shin Ichi

Polymer Journal　Vol. 48　No. 10　p. 999-1005　2016/10/01　Research paper (scientific journal)

Photoreactive Initiator for Surface-Initiated ATRP on Versatile Polymeric Substrates

Fukazawa Kyoko, Nakao Aiko, Maeda Mizuo, Ishihara Kazuhiko

ACS Applied Materials and Interfaces　Vol. 8　No. 38　p. 24994-24998　2016/09/28　Research paper (scientific journal)

Evaluation of wear suppression for phospholipid polymer-grafted ultra-high molecular weight polyethylene at concentrated contact

Uehara Shuichiro, Yarimitsu Seido, Moro Toru, Kyomoto Masayuki, Watanabe Kenichi, Tanaka Sakae, Ishihara Kazuhiko, Murakami Teruo

Tribology International　Vol. 101　p. 264-272　2016/09/01　Research paper (scientific journal)

Diffusion-Induced Hydrophilic Conversion of Polydimethylsiloxane/Block-Type Phospholipid Polymer Hybrid Substrate for Temporal Cell-Adhesive Surface

Seo Ji Hun, Ishihara Kazuhiko

ACS Applied Materials and Interfaces　Vol. 8　No. 33　p. 21839-21846　2016/08/24　Research paper (scientific journal)

High-efficiency preparation of poly(2-methacryloyloxyethyl phosphorylcholine) grafting layer on poly(ether ether ketone) by photoinduced and self-initiated graft polymerization in an aqueous solution in the presence of inorganic salt additives

Taro Shiojima, Yuuki Inoue, Masayuki Kyomoto, Kazuhiko Ishihara

Acta Biomaterialia　Vol. 40　p. 38-45　2016/08　Research paper (scientific journal)

Special issue on Zwitterionic Materials

Jiang Shaoyi, Ishihara Kazuhiko, Ji Jian

Acta Biomaterialia　Vol. 40　p. iv-IV　2016/08/01

Photoinduced detachment of cells adhered on 2-methacryloyloxyethyl phosphorylcholine polymer with cell binding molecule through photocleavable linkage

Byambaa Batzaya, Konno Tomohiro, Ishihara Kazuhiko

Reactive and Functional Polymers　Vol. 104　p. 30-37　2016/07/01　Research paper (scientific journal)

In situ patterning of organic molecules in aqueous solutions using an inverted electron-beam lithography system

Miyazako Hiroki, Ishihara Kazuhiko, Mabuchi Kunihiko, Hoshino Takayuki

Japanese Journal of Applied Physics　Vol. 55　No. 6　2016/06/01　Research paper (scientific journal)

Formation of Polyion Complex (PIC) Micelles and Vesicles with Anionic pH-Responsive Unimer Micelles and Cationic Diblock Copolymers in Water

Ohno Sayaka, Ishihara Kazuhiko, Yusa Shin Ichi

Langmuir　Vol. 32　No. 16　p. 3945-3953　2016/05/03　Research paper (scientific journal)

Preparation of a thick polymer brush layer composed of poly(2-methacryloyloxyethyl phosphorylcholine) by surface-initiated atom transfer radical polymerization and analysis of protein adsorption resistance

Inoue Yuuki, Onodera Yuya, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 141　p. 507-512　2016/05/01　Research paper (scientific journal)

ATP-mediated release of a DNA-binding protein from a silicon nanoneedle array

Matsumoto Daisuke, Nishio Maui, Kato Yoshio, Yoshida Wataru, Abe Koichi, Fukazawa Kyoko, Ishihara Kazuhiko, Iwata Futoshi, Ikebukuro Kazunori, Nakamura Chikashi

Electrochemistry　Vol. 84　No. 5　p. 305-307　2016/05/01　Research paper (scientific journal)

Temperature-responsive diblock copolymers bearing biocompatible pendant phosphorylcholine groups

Fukuda Kenichi, Ishihara Kazuhiko, Morishima Yotaro, Yusa Shin Ichi

Kobunshi Ronbunshu　Vol. 73　No. 2　p. 192-197　2016/03/01

Cytocompatible Magnetic Nanoparticles with Cell-internalizing Properties for Quantification of the Intracellular Environment

Kensuke Yoshie, Yuuki Inoue, Kazuhiko Ishihara

Transactions of the Materials Research Society of Japan　Vol. 41　No. 1　p. 113-116　2016　Research paper (scientific journal)

1H23 Isolation of undifferentiated iPS cells using microfluidic channel immobilized with anti-SSEA-1 antibody

OTAKA Akihisa, KITAGAWA Kazuki, HIRATA Mitsuhi, FUKAZAWA Kyoko, NAKAOKI Takahiko, ISHIHARA Kazuhiko, MAHARA Atsushi, YAMAOKA Tetsuji

The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME　Vol. 2016　No. 0　p. _1H23-1_-_1H23-4_　2016

Effects of extra irradiation on surface and bulk properties of PMPC-grafted cross-linked polyethylene

Yamane Shihori, Kyomoto Masayuki, Moro Toru, Watanabe Kenichi, Hashimoto Masami, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 104　No. 1　p. 37-47　2016/01/01　Research paper (scientific journal)

Advantages of anchoring growth factors to materials for neural stem/progenitor cell proliferation

Nakaji-Hirabayashi T, Fujimoto K, Kato Y, Kitano H, Inoue Y, Ishihara K

Journal of Materials Chemistry B　Vol. 4　No. 37　p. 6213-6220　2016　Research paper (scientific journal)

Clinical safety and wear resistance of the phospholipid polymer-grafted highly cross-linked polyethylene liner

Moro Toru, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko, Oda Hiromi, Kim Yoon Taek, Umeyama Takashige, Fukatani Eisei, Ito Hideya, Kyomoto Masayuki, Oshima Hirofumi, Tanaka Takeyuki, Kawaguchi Hiroshi, Nakamura Kozo

Journal of Orthopaedic Research　Vol. 35　No. 9　p. 2007-2016　2016　Research paper (scientific journal)

Direct interaction force and adsorption behavior of fibrinogen on well-characterized polymer brush surfaces

Sho Sakata, Yuuki Inoue, Kazuhiko Ishihara

Trans Mat Res Soc Japan　Vol. 41　No. 1　p. 51-54　2016　Research paper (scientific journal)

Cytocompatible magnetic nanoparticles with cell-internalizing properties for quantification of intracellular environment

Kensuke Yoshie, Yuuki Inoue, Kazuhiko Ishihara

Biomater Biomechanics Bioengineer　Vol. 3　No. 1　p. 37-46　2016　Research paper (scientific journal)

Enhanced stability of NADH/dehydrogenase mixture system by water-soluble phospholipid polymers

Kyoko Fukazawa, Kazuhiko Ishihara

Biomater Biomechanics Bioengineer　Vol. 3　No. 1　p. 37-46　2016　Research paper (scientific journal)

Photoinduced inhibition of DNA unwinding with water-soluble polymer containing both phosphorylcholine and photoreactive Groups

Xiaojie Lin, Kyoko Fukazawa, Kazuhiko Ishihara

Acta Biomater　Vol. 40　p. 226-234　2016　Research paper (scientific journal)

Fabrication of a live cell-containing multilayered polymer hydrogel membrane with micrometer-scale thickness to evaluate pharmaceutical activity

Gao Botao, Konno Tomohiro, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 26　No. 18　p. 1372-1385　2015/12/12　Research paper (scientific journal)

Surface functionalization of quantum dots with fine-structured pH-sensitive phospholipid polymer chains

Liu Yihua, Inoue Yuuki, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 135　p. 490-496　2015/11/01　Research paper (scientific journal)

Preparation of photoreactive phospholipid polymer nanoparticles to immobilize and release protein by photoirradiation

Chen Weixin, Inoue Yuuki, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 135　p. 365-370　2015/11/01　Research paper (scientific journal)

Spontaneous Packaging and Hypothermic Storage of Mammalian Cells with a Cell-Membrane-Mimetic Polymer Hydrogel in a Microchip

Xu Yan, Mawatari Kazuma, Konno Tomohiro, Kitamori Takehiko, Ishihara Kazuhiko

ACS Applied Materials and Interfaces　Vol. 7　No. 41　p. 23089-23097　2015/10/21　Research paper (scientific journal)

Phospholipid Polymer Grafted Highly Cross-Linked UHMWPE

Kyomoto Masayuki, Moro Toru, Ishihara Kazuhiko

UHMWPE Biomaterials Handbook: Ultra High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices: Third Edition　p. 352-368　2015/09/24　Part of collection (book)

Prevention of bacterial adhesion and biofilm formation on a vitamin E-blended, cross-linked polyethylene surface with a poly(2-methacryloyloxyethyl phosphorylcholine) layer

Kyomoto Masayuki, Shobuike Takeo, Moro Toru, Yamane Shihori, Takatori Yoshio, Tanaka Sakae, Miyamoto Hiroshi, Ishihara Kazuhiko

Acta Biomaterialia　Vol. 24　p. 24-34　2015/09/15　Research paper (scientific journal)

Highly lubricated polymer interfaces for advanced artificial hip joints through biomimetic design

Ishihara Kazuhiko

Polymer Journal　Vol. 47　No. 9　p. 585-597　2015/09/08

Photoreactive Polymers Bearing a Zwitterionic Phosphorylcholine Group for Surface Modification of Biomaterials

Lin Xiaojie, Fukazawa Kyoko, Ishihara Kazuhiko

ACS Applied Materials and Interfaces　Vol. 7　No. 31　p. 17489-17498　2015/08/12　Research paper (scientific journal)

Animal Experiments of the Helical Flow Total Artificial Heart

Abe Yusuke, Isoyama Takashi, Saito Itsuro, Inoue Yusuke, Ishii Kohei, Sato Masami, Hara Shintaro, Yurimoto Terumi, Li Xinyang, Murakami Haruka, Ariyoshi Koki, Kawase Yukino, Ono Toshiya, Fukazawa Kyoko, Ishihara Kazuhiko

Artificial Organs　Vol. 39　No. 8　p. 670-680　2015/08/01　Research paper (scientific journal)

Reactive ABA-type triblock phospholipid copolymer by ATRP and its chemical functionalizations

Chantasirichot Surasak, Inoue Yuuki, Ishihara Kazuhiko

Macromolecular Symposia　Vol. 354　No. 1　p. 104-110　2015/08/01　Research paper (international conference proceedings)

Surface modification on poly(ether ether ketone) with phospholipid polymer via photoinduced self-initiated grafting

Ishihara Kazuhiko, Inoue Yuuki, Kyomoto Masayuki

Macromolecular Symposia　Vol. 354　No. 1　p. 230-236　2015/08/01　Research paper (international conference proceedings)

Preparation of upper critical solution temperature (UCST) responsive diblock copolymers bearing pendant ureido groups and their micelle formation behavior in water

Fujihara Ami, Shimada Naohiko, Maruyama Atsushi, Ishihara Kazuhiko, Nakai Keita, Yusa Shin Ichi

Soft Matter　Vol. 11　No. 26　p. 5204-5213　2015/07/14　Research paper (scientific journal)

Influences of dehydration and rehydration on the lubrication properties of phospholipid polymer-grafted cross-linked polyethylene

Yarimitsu Seido, Moro Toru, Kyomoto Masayuki, Watanabe Kenichi, Tanaka Sakae, Ishihara Kazuhiko, Murakami Teruo

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine　Vol. 229　No. 7　p. 506-514　2015/07/03　Research paper (scientific journal)

Efficient differentiation of stem cells encapsulated in a cytocompatible phospholipid polymer hydrogel with tunable physical properties

Oda Haruka, Konno Tomohiro, Ishihara Kazuhiko

Biomaterials　Vol. 56　p. 86-91　2015/07/01　Research paper (scientific journal)

Wear resistance of the biocompatible phospholipid polymer-grafted highly cross-linked polyethylene liner against larger femoral head

Moro Toru, Takatori Yoshio, Kyomoto Masayuki, Ishihara Kazuhiko, Kawaguchi Hiroshi, Hashimoto Masami, Tanaka Takeyuki, Oshima Hirofumi, Tanaka Sakae

Journal of Orthopaedic Research　Vol. 33　No. 7　p. 1103-1110　2015/07/01　Research paper (scientific journal)

Bioinspired phospholipid polymer hydrogel system for cellular engineering

Ishihara Kazuhiko, Oda Haruka, Aikawa Tatsuo, Konno Tomohiro

Macromolecular Symposia　Vol. 351　No. 1　p. 69-77　2015/05/01　Research paper (international conference proceedings)

Preparation of biocompatible poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) via organotellulium-medicated radical polymerization (TERP)

Nakagawa Hinari, Yamago Shigeru, Ishihara Kazuhiko, Yusa Shin Ichi

Kobunshi Ronbunshu　Vol. 72　No. 5　p. 335-340　2015/05/01　Research paper (scientific journal)

Therapeutic effect of intravesical administration of paclitaxel solubilized with poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate) in an orthotopic bladder cancer model

Tamura Koetsu, Kikuchi Eiji, Konno Tomohiro, Ishihara Kazuhiko, Matsumoto Kazuhiro, Miyajima Akira, Oya Mototsugu

BMC Cancer　Vol. 15　No. 1　2015/04/26　Research paper (scientific journal)

Synthesis of grafted phosphorylcholine polymer layers as specific recognition ligands for C-reactive protein focused on grafting density and thickness to achieve highly sensitive detection

Kamon Yuri, Kitayama Yukiya, Itakura Akiko N, Fukazawa Kyoko, Ishihara Kazuhiko, Takeuchi Toshifumi

Physical Chemistry Chemical Physics　Vol. 17　No. 15　p. 9951-9958　2015/04/21　Research paper (scientific journal)

Critical update on 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer science

Tatsuro Goda, Kazuhiko Ishihara, Yuji Miyahara

Journal of Applied Polymer Science　Vol. 132　No. 16　p. 41766-n/a　2015/04/20　Research paper (scientific journal)

Safety, reliability, and operability of cochlear implant electrode arrays coated with biocompatible polymer

Kinoshita Makoto, Kikkawa, Yayoi S, Sakamoto Takashi, Kondo Kenji, Ishihara Kazuhiko, Konno Tomohiro, Pawsey Nick, Yamasoba Tatsuya

Acta Oto-Laryngologica　Vol. 135　No. 4　p. 320-327　2015/04/01　Research paper (scientific journal)

Cytocompatible and spontaneously forming phospholipid polymer hydrogels

Gao Botao, Konno Tomohiro, Ishihara Kazuhiko

European Polymer Journal　Vol. 72　p. 577-589　2015/03/30　Research paper (scientific journal)

Photoinduced atom transfer radical polymerization in a polar solvent to synthesize a water-soluble poly(2-methacryloyloxyethyl phosphorylcholine) and its block-type copolymers

Chantasirichot Surasak, Inoue Yuuki, Ishihara Kazuhiko

Polymer (United Kingdom)　Vol. 61　p. 55-60　2015/03/20　Research paper (scientific journal)

Molecular Interaction Forces Generated during Protein Adsorption to Well-Defined Polymer Brush Surfaces

Sakata Sho, Inoue Yuuki, Ishihara Kazuhiko

Langmuir　Vol. 31　No. 10　p. 3108-3114　2015/03/17　Research paper (scientific journal)

Hollow fiber membrane modification with functional zwitterionic macromolecules for improved thromboresistance in artificial lungs

Ye Sang Ho, Arazawa David T, Zhu Yang, Shankarraman Venkat, Malkin Alexander D, Kimmel Jeremy D, Gamble Lara J, Ishihara Kazuhiko, Federspiel William J, Wagner William R

Langmuir　Vol. 31　No. 8　p. 2463-2471　2015/03/03　Research paper (scientific journal)

Concentration-dependent effects of fibronectin adsorbed on hydroxyapatite surfaces on osteoblast adhesion

Matsui Natsuno, Nozaki Kosuke, Ishihara Kazuhiko, Yamashita Kimihiro, Nagai Akiko

Materials Science and Engineering C　Vol. 48　p. 378-383　2015/03/01　Research paper (scientific journal)

Initial Cell Adhesion on Well-Defined Surface by Polymer Brush Layers with Varying Chemical Structures

Ishihara Kazuhiko, Kitagawa Tomomi, Inoue Yuuki

ACS Biomaterial Science and Engineering　Vol. 1　No. 2　p. 103-109　2015/02/09　Research paper (scientific journal)

Aggregation behavior in water of amphiphilic diblock copolymers bearing biocompatible phosphorylcholine and cholesteryl groups

Ohno Sayaka, Hasegawa Shoto, Liu Huihua, Ishihara Kazuhiko, Yusa Shin Ichi

Polymer Journal　Vol. 47　No. 1　p. 71-76　2015/01/01　Research paper (scientific journal)

Mobility of the Arg-Gly-Asp ligand on the outermost surface of biomaterials suppresses integrin-mediated mechanotransduction and subsequent cell functions

Kakinoki Sachiro, Seo Ji Hun, Inoue Yuuki, Ishihara Kazuhiko, Yui Nobuhiko, Yamaoka Tetsuji

Acta Biomaterialia　Vol. 13　p. 42-51　2015/01/01　Research paper (scientific journal)

Clinical and radiographic outcomes of total hip replacement with poly(2-methacryloyloxyethyl phosphorylcholine)-grafted highly cross-linked polyethylene liners

Takatori Yoshio, Moro Toru, Ishihara Kazuhiko, Kamogawa Morihide, Oda Hiromi, Umeyama Takashige, Kim Yoon Taek, Ito Hideya, Kyomoto Masayuki, Tanaka Takeyuki, Kawaguchi Hiroshi, Tanaka Sakae

Modern Rheumatology　Vol. 25　No. 2　p. 286-291　2015　Research paper (scientific journal)

Building cell-containing multilayered phospholipid polymer hydrogels for controlling the diffusion of a bioactive reagent

Gao Botao, Konno Tomohiro, Ishihara Kazuhiko

RSC Advances　Vol. 5　No. 55　p. 44408-44415　2015　Research paper (scientific journal)

Poly(dimethylsiloxane) (PDMS) surface patterning by biocompatible photo-crosslinking block copolymers

Kuroda Keita, Miyoshi Hiromi, Fujii Shota, Hirai Tomoyasu, Takahara Atsushi, Nakao Aiko, Iwasaki Yasuhiko, Morigaki Kenichi, Ishihara Kazuhiko, Yusa Shin Ichi

RSC Advances　Vol. 5　No. 58　p. 46686-46693　2015　Research paper (scientific journal)

Effects of surface modification and bulk geometry on the biotribological behavior of cross-linked polyethylene

Watanabe Kenichi, Kyomoto Masayuki, Saiga Kenichi, Taketomi Shuji, Inui Hiroshi, Kadono Yuho, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko, Moro Toru

BioMed Research International　Vol. 2015　2015　Research paper (scientific journal)

Static friction force between catalyst layer and micro porous layer and its effect on deformations of membrane electrode assemblies under swelling

Uchiyama Tomoaki, Kumei Hideyuki, Yoshida Toshihiko, Ishihara Kazuhiko

Journal of Power Sources　Vol. 272　p. 522-530　2014/12/25　Research paper (scientific journal)

Novel Bioinspired Phospholipid Polymer Biomaterials for Nanobioengineering

Ishihara Kazuhiko

Bio- and Bioinspired Nanomaterials　p. 369-390　2014/12/03　Part of collection (book)

Biomimetic Interfaces Reveal Activation Dynamics of C-Reactive Protein in Local Microenvironments

Goda Tatsuro, Kjall Peter, Ishihara Kazuhiko, Richter-Dahlfors Agneta, Miyahara Yuji

Advanced healthcare materials　Vol. 3　No. 11　p. 1733-1738　2014/11/01　Research paper (scientific journal)

Multidirectional Wear and Impact-to-wear Tests of Phospholipid-polymer-grafted and Vitamin E-blended Crosslinked Polyethylene

Kyomoto Masayuki, Moro Toru, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko

Clinical Orthopaedics and Related Research　Vol. 473　No. 3　p. 942-951　2014/10/24　Research paper (scientific journal)

Investigation of the right blood pump for the helical flow total artificial heart

Yurimoto Terumi, Saito Itsuro, Isoyama Takashi, Inoue Yusuke, Sato Masami, Hara Shintaro, Li Xin Yang, Murakami Haruka, Kawase Yukino, Ono Toshiya, Fukazawa Kyoko, Ishihara Kazuhiko, Ono Minoru, Abe Yusuke

Transactions of Japanese Society for Medical and Biological Engineering　Vol. 52　p. O-532-O-533　2014/08/17　Research paper (scientific journal)

Design concept and elemental technologies of the helical flow total artificial heart

Abe Yusuke, Isoyama Takashi, Saito Itsuro, Yurimoto Terumi, Hara Shintaro, Li Xin Yang, Murakami Haruka, Kawase Yukino, Sato Masami, Inoue Yusuke, Ono Toshiya, Fukazawa Kyoko, Ishihara Kazuhiko, Takai Madoka, Ono Minoru

Transactions of Japanese Society for Medical and Biological Engineering　Vol. 52　p. OS-1-OS-2　2014/08/17　Research paper (scientific journal)

Amphiphilic triblock phospholipid copolymers bearing phenylboronic acid groups for spontaneous formation of hydrogels with tunable mechanical properties

Chantasirichot Surasak, Inoue Yuuki, Ishihara Kazuhiko

Macromolecules　Vol. 47　No. 9　p. 3128-3135　2014/05/13　Research paper (scientific journal)

Effects of molecular architecture of phospholipid polymers on surface modification of segmented polyurethanes

Liu Yihua, Inoue Yuuki, Sakata Sho, Kakinoki Sachiro, Yamaoka Tetsuji, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 5　p. 474-486　2014/03/24　Research paper (scientific journal)

Calcium mediated formation of phosphorylcholine-based polyplexes for efficient knockdown of epidermal growth factor receptors (EGFR) in HeLa cells

Ahmed Marya, Ishihara Kazuhiko, Narain Ravin

Chemical Communications　Vol. 50　No. 22　p. 2943-2946　2014/03/18　Research paper (scientific journal)

Long-term hip simulator testing of the artificial hip joint bearing surface grafted with biocompatible phospholipid polymer

Moro Toru, Takatori Yoshio, Kyomoto Masayuki, Ishihara Kazuhiko, Hashimoto Masami, Ito Hideya, Tanaka Takeyuki, Oshima Hirofumi, Tanaka Shigeyuki, Kawaguchi Hiroshi

Journal of Orthopaedic Research　Vol. 32　No. 3　p. 369-376　2014/03/01　Research paper (scientific journal)

Grafting of poly(2-methacryloyloxyethyl phosphorylcholine) on polyethylene liner in artificial hip joints reduces production of wear particles

Moro Toru, Kyomoto Masayuki, Ishihara Kazuhiko, Saiga Kenichi, Hashimoto Masami, Tanaka Sakae, Ito Hideya, Tanaka Takeyuki, Oshima Hirofumi, Kawaguchi Hiroshi, Takatori Yoshio

Journal of the Mechanical Behavior of Biomedical Materials　Vol. 31　p. 100-106　2014/03/01　Research paper (scientific journal)

Regulation of the cyanobacterial circadian clock by electrochemically controlled extracellular electron transfer

Lu Yue, Nishio Koichi, Matsuda Shoichi, Toshima Yuki, Ito Hiroshi, Konno Tomohiro, Ishihara Kazuhiko, Kato Souichiro, Hashimoto Kazuhito, Nakanishi Shuji

Angewandte Chemie - International Edition　Vol. 53　No. 8　p. 2208-2211　2014/02/17

Quantitating distance-dependent, indirect cell-cell interactions with a multilayered phospholipid polymer hydrogel

Gao Botao, Konno Tomohiro, Ishihara Kazuhiko

Biomaterials　Vol. 35　No. 7　p. 2181-2187　2014/02/01　Research paper (scientific journal)

Comprehensive genetic analysis of early host body reactions to the bioactive and bio-inert porous scaffolds

Ehashi Tomo, Takemura Taro, Hanagata Nobutaka, Minowa Takashi, Kobayashi Hisatoshi, Ishihara Kazuhiko, Yamaoka Tetsuji

PLoS One　Vol. 9　No. 1　2014/01/14　Research paper (scientific journal)

Cell-membrane-permeable and cytocompatible phospholipid polymer nanoprobes conjugated with molecular beacons

Lin Xiaojie, Konno Tomohiro, Ishihara Kazuhiko

Biomacromolecules　Vol. 15　No. 1　p. 150-157　2014/01/13　Research paper (scientific journal)

Investigation of right blood pump for helical flow total artificial heart

Yurimoto Terumi, Saito Itsuro, Isoyama Takashi, Inoue Yusuke, Sato Masami, Hara Shintaro, Li Xinyang, Murakami Haruka, Wu Sheng Yuan, Kawase Yukino, Ishihara Kazuhiko, Abe Yusuke

BME　Vol. 52　p. O-532-O-533　2014

分子インプリント法によるバイオ分子認識表面の創製

深澤 今日子, 石原 一彦

人工臓器　Vol. 43　No. 3　p. 202-205　2014

Quantitative evaluation of interaction force between functional groups in protein and polymer brush surfaces

Sakata Sho, Inoue Yuuki, Ishihara Kazuhiko

Langmuir　Vol. 30　No. 10　p. 2745-2751　2014/01/01　Research paper (scientific journal)

Neutron reflectivity study of the swollen structure of polyzwitterion and polyeletrolyte brushes in aqueous solution

Kobayashi Motoyasu, Ishihara Kazuhiko, Takahara Atsushi

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 14-15　p. 1673-1686　2014/01/01　Research paper (scientific journal)

Foreword

Jiang Shaoyi, Ishihara Kazuhiko, Cooper Stuart

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 14-15　p. 1459-1460　2014/01/01

Effect of UV-irradiation intensity on graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on orthopedic bearing substrate

Kyomoto Masayuki, Moro Toru, Yamane Shihori, Hashimoto Masami, Takatori Yoshio, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 102　No. 9　p. 3012-3023　2014/01/01　Research paper (scientific journal)

Poly(2-methacryloyloxyethyl phosphorylcholine) grafting and vitamin E blending for high wear resistance and oxidative stability of orthopedic bearings

Kyomoto Masayuki, Moro Toru, Yamane Shihori, Watanabe Kenichi, Hashimoto Masami, Takatori Yoshio, Tanaka Sakae, Ishihara Kazuhiko

Biomaterials　Vol. 35　No. 25　p. 6677-6686　2014/01/01　Research paper (scientific journal)

Reduced platelets and bacteria adhesion on poly(ether ether ketone) by photoinduced and self-initiated graft polymerization of 2-methacryloyloxyethyl phosphorylcholine

Tateishi Takaharu, Kyomoto Masayuki, Kakinoki Sachiro, Yamaoka Tetsuji, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 102　No. 5　p. 1342-1349　2014/01/01　Research paper (scientific journal)

Quantitative evaluation of interaction force of fibrinogen at well-defined surfaces with various structures

Chen Weixin, Inoue Yuuki, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 14-15　p. 1629-1640　2014/01/01　Research paper (scientific journal)

Detection of microtubules in vivo using antibody-immobilized nanoneedles

Silberberg Yaron R, Kawamura Ryuzo, Ryu Seunghwan, Fukazawa Kyoko, Ishihara Kazuhiko, Nakamura Chikashi

Journal of Bioscience and Bioengineering　Vol. 117　No. 1　p. 107-112　2014/01/01　Research paper (scientific journal)

Water-soluble polymers bearing phosphorylcholine group and other zwitterionic groups for carrying DNA derivatives

Lin Xiaojie, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 14-15　p. 1461-1478　2014/01/01

Evaluation of the durability and antiadhesive action of 2-methacryloyloxyethyl phosphorylcholine grafting on an acrylic resin denture base material

Takahashi Nana, Iwasa Fuminori, Inoue Yuuki, Morisaki Hirobumi, Ishihara Kazuhiko, Baba Kazuyoshi

Journal of Prosthetic Dentistry　Vol. 112　No. 2　p. 194-203　2014/01/01　Research paper (scientific journal)

Surface patterned graft copolymerization of hydrophilic monomers onto hydrophobic polymer film upon UV irradiation

Enomoto Ryusuke, Sato Masanao, Fujii Shota, Hirai Tomoyasu, Takahara Atsushi, Ishihara Kazuhiko, Yusa Shin Ichi

Journal of Polymer Science, Part A: Polymer Chemistry　Vol. 52　No. 19　p. 2822-2829　2014/01/01　Research paper (scientific journal)

Thermo-responsive and biocompatible diblock copolymers prepared via reversible addition-fragmentation chain transfer (RAFT) radical polymerization

Fukuda Kenichi, Enomoto Ryusuke, Ishihara Kazuhiko, Morishima Yotaro, Yusa Shin Ichi

Polymers　Vol. 6　No. 3　p. 846-859　2014/01/01　Research paper (scientific journal)

Gene chip/PCR-array analysis of tissue response to 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer surfaces in a mouse subcutaneous transplantation system

Kakinoki Sachiro, Sakai Yusuke, Takemura Taro, Hanagata Nobutaka, Fujisato Toshia, Ishihara Kazuhiko, Yamaoka Tetsuji

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 14-15　p. 1658-1672　2014/01/01　Research paper (scientific journal)

Durable modification of segmented polyurethane for elastic blood-contacting devices by graft-type 2-methacryloyloxyethyl phosphorylcholine copolymer

Liu Yihua, Inoue Yuuki, Mahara Atsushi, Kakinoki Sachiro, Yamaoka Tetsuji, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 14-15　p. 1514-1529　2014/01/01　Research paper (scientific journal)

Phospholipid polymer-based antibody immobilization for cell rolling surfaces in stem cell purification system

Mahara Atsushi, Chen Hao, Ishihara Kazuhiko, Yamaoka Tetsuji

Journal of Biomaterials Science, Polymer Edition　Vol. 25　No. 14-15　p. 1590-1601　2014/01/01　Research paper (scientific journal)

2-methacryloyloxyethyl phosphorylcholine polymers

Ishihara Kazuhiko, Fukazawa Kyoko

RSC Polymer Chemistry Series　Vol. 2014-January　No. 11　p. 68-96　2014　Research paper (scientific journal)

Zwitterion biomaterials. Foreword

Jiang Shaoyi, Ishihara Kazuhiko, Cooper Stuart

Journal of biomaterials science. Polymer edition　Vol. 25　No. 14-15　p. 1459-1460　2014

Release of potassium ion and calcium ion from phosphorylcholine group bearing hydrogels

Aucoin Hanna R, Wilson A. Nolan, Wilson Ann M, Ishihara Kazuhiko, Guiseppi-Elie Anthony

Polymers　Vol. 5　No. 4　p. 1241-1257　2013/12/18　Research paper (scientific journal)

Extracellular Electron Transfer Enhances Polyhydroxybutyrate Productivity in Ralstonia eutropha

Nishio Koichi, Kimoto Yuki, Song Jieun, Konno Tomohiro, Ishihara Kazuhiko, Kato Souichiro, Hashimoto Kazuhito, Nakanishi Shuji

Environmental Science and Technology Letters　Vol. 1　No. 1　p. 40-43　2013/11/11　Research paper (scientific journal)

The helical flow total artificial heart

Abe Yusuke, Ishii Kohei, Isoyama Takashi, Saito Itsuro, Inoue Yusuke, Sato Masami, Hara Shintaro, Hosoda Kyohei, Ariyoshi Koki, Nakagawa Hidemoto, Ono Toshiya, Fukazawa Kyoko, Ishihara Kazuhiko, Imachi Kou

2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)　p. 2720-2723　2013/10/31　Research paper (international conference proceedings)

Preparation of amphiphilic diblock copolymers with pendant hydrophilic phosphorylcholine and hydrophobic dendron groups and their self-association behavior in water

Osawa Kazuki, Imae Toyoko, Ujihara Masaki, Harada Atsushi, Ochi Kanako, Ishihara Kazuhiko, Yusa Shin Ichi

Journal of Polymer Science, Part A: Polymer Chemistry　Vol. 51　No. 22　p. 4923-4931　2013/10/11　Research paper (scientific journal)

Poly(ether-ether-ketone) orthopedic bearing surface modified byself-initiated surface grafting of poly(2-methacryloyloxyethyl phosphorylcholine)

Kyomoto Masayuki, Moro Toru, Yamane Shihori, Hashimoto Masami, Takatori Yoshio, Ishihara Kazuhiko

Biomaterials　Vol. 34　No. 32　p. 7829-7839　2013/10/01　Research paper (scientific journal)

Elastic repulsion from polymer brush layers exhibiting high protein repellency

Inoue Yuuki, Nakanishi Tomoaki, Ishihara Kazuhiko

Langmuir　Vol. 29　No. 34　p. 10752-10758　2013/08/27　Research paper (scientific journal)

Synthesis of photoreactive phospholipid polymers for use in versatile surface modification of various materials to obtain extreme wettability

Fukazawa Kyoko, Ishihara Kazuhiko

ACS Applied Materials and Interfaces　Vol. 5　No. 15　p. 6832-6836　2013/08/14　Research paper (scientific journal)

Preparation and characterization of polyion complex micelles with phosphobetaine shells

Nakai Keita, Nishiuchi Midori, Inoue Masamichi, Ishihara Kazuhiko, Sanada Yusuke, Sakurai Kazuo, Yusa Shin Ichi

Langmuir　Vol. 29　No. 31　p. 9651-9661　2013/08/06　Research paper (scientific journal)

A large mobility of hydrophilic molecules at the outmost layer controls the protein adsorption and adhering behavior with the actin fiber orientation of human umbilical vein endothelial cells (HUVEC)

Kakinoki Sachiro, Seo Ji Hun, Inoue Yuuki, Ishihara Kazuhiko, Yui Nobuhiko, Yamaoka Tetsuji

Journal of Biomaterials Science, Polymer Edition　Vol. 24　No. 11　p. 1320-1332　2013/08/01　Research paper (scientific journal)

Hybridization of poly(2-methacryloyloxyethyl phosphorylcholine-block-2-ethylhexyl methacrylate) with segmented polyurethane for reducing thrombogenicity

Asanuma Yoshiharu, Inoue Yuuki, Yusa Shin Ichi, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 108　p. 239-245　2013/08/01　Research paper (scientific journal)

A simple procedure for the preparation of precise spatial multicellular phospholipid polymer hydrogels

Gao Botao, Konno Tomohiro, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 108　p. 345-351　2013/08/01　Research paper (scientific journal)

The use of the mechanical microenvironment of phospholipid polymer hydrogels to control cell behavior

Oda Haruka, Konno Tomohiro, Ishihara Kazuhiko

Biomaterials　Vol. 34　No. 24　p. 5891-5896　2013/08/01　Research paper (scientific journal)

Extracellular electron transfer across bacterial cell membranes via a cytocompatible redox-active polymer

Nishio Koichi, Nakamura Ryuhei, Lin Xiaojie, Konno Tomohiro, Ishihara Kazuhiko, Nakanishi Shuji, Hashimoto Kazuhito

ChemPhysChem　Vol. 14　No. 10　p. 2159-2163　2013/07/22　Research paper (scientific journal)

Surface modification of a biodegradable magnesium alloy with phosphorylcholine (PC) and sulfobetaine (SB) functional macromolecules for reduced thrombogenicity and acute corrosion resistance

Ye Sang Ho, Jang Yong Seok, Yun Yeo Heung, Shankarraman Venkat, Woolley Joshua R, Hong Yi, Gamble Lara J, Ishihara Kazuhiko, Wagner William R

Langmuir　Vol. 29　No. 26　p. 8320-8327　2013/07/02　Research paper (scientific journal)

Phospholipid polymer hydrogel microsphere modulates the cell cycle profile of encapsulated cells

Aikawa Tatsuo, Konno Tomohiro, Ishihara Kazuhiko

Soft Matter　Vol. 9　No. 18　p. 4628-4634　2013/05/14　Research paper (scientific journal)

Linear and hyperbranched phosphorylcholine based homopolymers for blood biocompatibility

Jawanda Manraj, Lai Benjamin F L, Kizhakkedathu Jayachandran N, Ishihara Kazuhiko, Narain Ravin

Polymer Chemistry　Vol. 4　No. 10　p. 3140-3146　2013/05/06　Research paper (scientific journal)

Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces

Seo Ji Hun, Kakinoki Sachiro, Inoue Yuuki, Yamaoka Tetsuji, Ishihara Kazuhiko, Yui Nobuhiko

Journal of the American Chemical Society　Vol. 135　No. 15　p. 5513-5516　2013/04/17　Research paper (scientific journal)

The significance of hydrated surface molecular mobility in the control of the morphology of adhering fibroblasts

Seo Ji Hun, Kakinoki Sachiro, Inoue Yuuki, Nam Kwangwoo, Yamaoka Tetsuji, Ishihara Kazuhiko, Kishida Akio, Yui Nobuhiko

Biomaterials　Vol. 34　No. 13　p. 3206-3214　2013/04/01　Research paper (scientific journal)

Direct electron transfer with enzymes on nanofiliform titanium oxide films with electron-transport ability

Lee So Yoon, Matsuno Ryosuke, Ishihara Kazuhiko, Takai Madoka

Biosensors and Bioelectronics　Vol. 41　No. 1　p. 289-293　2013/03/15　Research paper (scientific journal)

Detachment of cells adhered on the photoreactive phospholipid polymer surface by photoirradiation and their functionality

Byambaa Batzaya, Konno Tomohiro, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 103　p. 489-495　2013/03/01　Research paper (scientific journal)

Relaxation modes in chemically cross-linked poly(2-methacryloyloxyethyl phosphorylcholine) hydrogels

Goda Tatsuro, Furukawa Hidemitsu, Gong Jian Ping, Ishihara Kazuhiko

Soft Matter　Vol. 9　No. 7　p. 2166-2171　2013/02/21　Research paper (scientific journal)

Evaluation of the actin cytoskeleton state using an antibody-functionalized nanoneedle and an AFM

Silberberg Yaron R, Mieda Shingo, Amemiya Yosuke, Sato Toshiya, Kihara Takanori, Nakamura Noriyuki, Fukazawa Kyoko, Ishihara Kazuhiko, Miyake Jun, Nakamura Chikashi

Biosensors and Bioelectronics　Vol. 40　No. 1　p. 3-9　2013/02/15　Research paper (scientific journal)

Direct observation of selective protein capturing on molecular imprinting substrates

Fukazawa Kyoko, Li Qiang, Seeger Stefan, Ishihara Kazuhiko

Biosensors and Bioelectronics　Vol. 40　No. 1　p. 96-101　2013/02/15　Research paper (scientific journal)

Redox phospholipid polymer microparticles as doubly functional polymer support for immobilization of enzyme oxidase

Lin Xiaojie, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 102　p. 857-863　2013/02/01　Research paper (scientific journal)

Relaxation modes in chemically cross-linked poly(2-methacryloyloxyethyl phosphorylcholine) hydrogels.

Tatsuro Goda, Hidemitsu Furukawa, Jian Ping Gong, Kazuhiko Ishihara

Soft Matter　Vol. 9　No. 7　p. 2166-2171　2013/01　Research paper (scientific journal)

Enhanced and specific internalization of polymeric nanoparticles to cells

Ishihara Kazuhiko, Tsukamoto Yuriko, Goto Yusuke, Inoue Yuuki

IFMBE Proceedings　Vol. 40　p. 262-265　2013/01/01　Research paper (international conference proceedings)

The helical flow total artificial heart

Abe Yusuke, Ishii Kohei, Isoyama Takashi, Saito Itsuro, Inoue Yusuke, Sato Masami, Hara Shintaro, Hosoda Kyohei, Ariyoshi Koki, Nakagawa Hidemoto, Ono Toshiya, Fukazawa Kyoko, Ishihara Kazuhiko, Imachi Kou

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference　Vol. 2013　p. 2720-2723　2013　Research paper (international conference proceedings)

Clarification of protein adsorption at polymer brush surfaces based on water structure surrounding the surface

Inoue Yuuki, Ishihara Kazuhiko

PROTEINS AT INTERFACES III: STATE OF THE ART　Vol. 1120　p. 605-620　2012/12/12　Research paper (international conference proceedings)

Cell membrane-inspired phospholipid polymers for developing medical devices with excellent biointerfaces

Iwasaki Yasuhiko, Ishihara Kazuhiko

Science and Technology of Advanced Materials　Vol. 13　No. 6　2012/12/01　Research paper (scientific journal)

The helical flow pump with a hydrodynamic levitation impeller

Abe Yusuke, Ishii Kohei, Isoyama Takashi, Saito Itsuro, Inoue Yusuke, Ono Toshiya, Nakagawa Hidemoto, Nakano Emiko, Fukazawa Kyoko, Ishihara Kazuhiko, Fukunaga Kazuyoshi, Ono Minoru, Imachi Kou

Journal of Artificial Organs　Vol. 15　No. 4　p. 331-340　2012/12/01　Research paper (scientific journal)

Modification of glass substrates and microfluidic devices by silanization of bioinspired 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers for preparing biocompatible interfaces

Xu Yan, Takai Madoka, Ishihara Kazuhiko

p. 1-47　2012/11/01

The effect of the encapsulation of bacteria in redox phospholipid polymer hydrogels on electron transfer efficiency in living cell-based devices

Lin Xiaojie, Nishio Koichi, Konno Tomohiro, Ishihara Kazuhiko

Biomaterials　Vol. 33　No. 33　p. 8221-8227　2012/11/01　Research paper (scientific journal)

Impact of the nature, size and chain topologies of carbohydrate-phosphorylcholine polymeric gene delivery systems

Ahmed Marya, Jawanda Manraj, Ishihara Kazuhiko, Narain Ravin

Biomaterials　Vol. 33　No. 31　p. 7858-7870　2012/11/01　Research paper (scientific journal)

Cell adhesion control on photoreactive phospholipid polymer surfaces

Byambaa Batzaya, Konno Tomohiro, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 99　p. 1-6　2012/11/01　Research paper (scientific journal)

Electrospun phospholipid polymer substrate for enhanced performance in immunoassay system

Chantasirichot Surasak, Ishihara Kazuhiko

Biosensors and Bioelectronics　Vol. 38　No. 1　p. 209-214　2012/10/01　Research paper (scientific journal)

Simple surface treatment using amphiphilic phospholipid polymers to obtain wetting and lubricity on polydimethylsiloxane-based substrates

Fukazawa Kyoko, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 97　p. 70-76　2012/09/01　Research paper (scientific journal)

QCM-D analysis of material-cell interactions targeting a single cell during initial cell attachment

Watarai Etsuko, Matsuno Ryosuke, Konno Tomohiro, Ishihara Kazuhiko, Takai Madoka

Sensors and Actuators, B: Chemical　Vol. 171-172　p. 1297-1302　2012/08/01　Research paper (scientific journal)

Biomimetic hydration lubrication with various polyelectrolyte layers on cross-linked polyethylene orthopedic bearing materials

Kyomoto Masayuki, Moro Toru, Saiga Kenichi, Hashimoto Masami, Ito Hideya, Kawaguchi Hiroshi, Takatori Yoshio, Ishihara Kazuhiko

Biomaterials　Vol. 33　No. 18　p. 4451-4459　2012/06/01　Research paper (scientific journal)

Biomimetic hydrogels gate transport of calcium ions across cell culture inserts

Kotanen Christian N, Wilson A. Nolan, Wilson Ann M, Ishihara Kazuhiko, Guiseppi-Elie Anthony

Biomedical Microdevices　Vol. 14　No. 3　p. 549-558　2012/06/01　Research paper (scientific journal)

Designing dynamic surfaces for regulation of biological responses

Seo Ji Hun, Kakinoki Sachiro, Inoue Yuuki, Yamaoka Tetsuji, Ishihara Kazuhiko, Yui Nobuhiko

Soft Matter　Vol. 8　No. 20　p. 5477-5485　2012/05/28　Research paper (scientific journal)

Wettability and antifouling behavior on the surfaces of superhydrophilic polymer brushes

Kobayashi Motoyasu, Terayama Yuki, Yamaguchi Hiroki, Terada Masami, Murakami Daiki, Ishihara Kazuhiko, Takahara Atsushi

Langmuir　Vol. 28　No. 18　p. 7212-7222　2012/05/08　Research paper (scientific journal)

Platelet adhesion-resistance of titanium substrate with mussel-inspired adhesive polymer bearing phosphorylcholine group

Yao Ye, Fukazawa Kyoko, Ma Wenyong, Ishihara Kazuhiko, Huang Nan

Applied Surface Science　Vol. 258　No. 14　p. 5418-5423　2012/05/01　Research paper (scientific journal)

Photodynamic therapy using PMB polymer as a new nanotransporter of verteporfin for the treatment of lymph node metastasis in breast cancer

Matsuda Sachiko, Jinno Hiromitsu, Shimada Kyosuke, Itano Osamu, Kameyamal Noriaki, Ito Arisa, Arai Tsunenori, Konno Tomohiro, Ishihara Kazuhiko, Kitagawa Yuko

CANCER RESEARCH　Vol. 72　2012/04/15

Fabrication of polymeric electron-transfer mediator/enzyme hydrogel multilayer on an Au electrode in a layer-by-layer process

Li Ziyin, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Biosensors and Bioelectronics　Vol. 34　No. 1　p. 191-196　2012/04/15　Research paper (scientific journal)

Cytocompatible and spontaneously forming phospholipid polymer hydrogels for encapsulation and function control of cells

Aikawa Tatsuo, Konno Tomohiro, Inoue Yuuki, Ishihara Kazuhiko

Abstracts of Papers of the American Chemical Society　Vol. 243　2012/03/25

Cytocompatible hydrogel composed of phospholipid polymers for regulation of cell functions

Ishihara Kazuhiko, Xu Yan, Konno Tomohiro

POLYMERS IN NANOMEDICINE　Vol. 247　p. 141-165　2012/03/16　Part of collection (book)

Suppression of inflammatory reactions on MPC polymer surfaces

Iwasaki Yasuhiko, Ishihara Kazuhiko

Handbook of Intelligent Scaffolds For Tissue Engineering and Regenerative Medicine　p. 365-383　2012/01/31　Research paper (scientific journal)

Spherical phospholipid polymer hydrogels for cell encapsulation prepared with a flow-focusing microfluidic channel device

Aikawa Tatsuo, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Langmuir　Vol. 28　No. 4　p. 2145-2150　2012/01/31　Research paper (scientific journal)

Degradable thermoresponsive nanogels for protein encapsulation and controlled release

Bhuchar Neha, Sunasee Rajesh, Ishihara Kazuhiko, Thundat Thomas, Narain Ravin

Bioconjugate Chemistry　Vol. 23　No. 1　p. 75-83　2012/01/18　Research paper (scientific journal)

Mechanical force-based probing of intracellular proteins from living cells using antibody-immobilized nanoneedles

Mieda Shingo, Amemiya Yosuke, Kihara Takanori, Okada Tomoko, Sato Toshiya, Fukazawa Kyoko, Ishihara Kazuhiko, Nakamura Noriyuki, Miyake Jun, Nakamura Chikashi

Biosensors and Bioelectronics　Vol. 31　No. 1　p. 323-329　2012/01/15　Research paper (scientific journal)

Preparation and surface properties of polyrotaxane-containing tri-block copolymers as a design for dynamic biomaterials surfaces.

Yuuki Inoue, Lin Ye, Kazuhiko Ishihara, Nobuhiko Yui

Colloids Surf B Biointerfaces　Vol. 89　No. 1　p. 223-227　2012/01　Research paper (scientific journal)

Unification of cell cycle with cytocompatible and reversible-forming polymer hydrogels

Ishihara K, Oda H, Aikawa T, Konno T

Journal of Tissue Engineering and Regenerative Medicine　Vol. 6　p. 386-386　2012

Temperature-flexible cell microcontainers fabricated with a phosphorylcholine polymer hydrogel on chip

Xu Yan, Mawatari Kazuma, Konno Tomohiro, Ishihara Kazuhiko, Kitamori Takehiko

p. 1048-1050　2012/01/01

Regulation of cell proliferation by multi-layered phospholipid polymer hydrogel coatings through controlled release of paclitaxel

Choi Jiyeon, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Biomaterials　Vol. 33　No. 3　p. 954-961　2012/01/01　Research paper (scientific journal)

Preparation and surface properties of polyrotaxane-containing tri-block copolymers as a design for dynamic biomaterials surfaces

Inoue Yuuki, Ye Lin, Ishihara Kazuhiko, Yui Nobuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 89　No. 1　p. 223-227　2012/01/01　Research paper (scientific journal)

Chain dimension of polyampholytes in solution and immobilized brush states

Kikuchi Moriya, Terayama Yuki, Ishikawa Tatsuya, Hoshino Taiki, Kobayashi Motoyasu, Ogawa Hiroki, Masunaga Hiroyasu, Koike Jun Ichiro, Horigome Misao, Ishihara Kazuhiko, Takahara Atsushi

Polymer Journal　Vol. 44　No. 1　p. 121-130　2012/01/01　Research paper (scientific journal)

Proposal of a new method for evaluating the frictional properties of tissue engineered cartilage

Tamura N, Arai M, Iwasaki Y, Ishihara K, Tamada Y, Tomita N

WIT Transactions on Engineering Sciences　Vol. 76　p. 89-97　2012　Research paper (international conference proceedings)

Biomimetic polymer nanoparticles embedding quantum dots

Ishihara Kazuhiko, Goto Yusuke, Matsuno Ryosuke

Materials Research Society Symposium Proceedings　Vol. 1357　p. 12-17　2011/12/01　Research paper (international conference proceedings)

Direct force measurement of protein adsorption on well-defined polymer nanointerfaces

Ishihara Kazuhiko, Nakanishi Tomoaki, Inoue Yuuki

2011/12/01

Erratum

Bhuchar Neha, Deng Zhicheng, Ishihara Kazuhiko, Narain Ravin

Polymer Chemistry　Vol. 2　No. 12　2011/12/01

Photodynamic therapy using an anti-EGF receptor antibody complexed with verteporfin nanoparticles

Kameyama Noriaki, Matsuda Sachiko, Itano Osamu, Ito Arisa, Konno Tomohiro, Arai Tsunenori, Ishihara Kazuhiko, Ueda Masakazu, Kitagawa Yuko

Cancer Biotherapy and Radiopharmaceuticals　Vol. 26　No. 6　p. 697-704　2011/12/01　Research paper (scientific journal)

Synthesis of polyurethanes by polyaddition using diol compounds with methacrylate-derived functional groups

Takami Kimiaki, Matsuno Ryosuke, Ishihara Kazuhiko

Polymer　Vol. 52　No. 24　p. 5445-5451　2011/11/10　Research paper (scientific journal)

Effects of 3,4-dihydrophenyl groups in water-soluble phospholipid polymer on stable surface modification of titanium alloy

Yao Ye, Fukazawa Kyoko, Huang Nan, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 88　No. 1　p. 215-220　2011/11/01　Research paper (scientific journal)

A bioconjugated phospholipid polymer biointerface with nanometer-scaled structure for highly sensitive immunoassays.

Nishizawa Kazuki, Takai Madoka, Ishihara Kazuhiko

Methods in molecular biology (Clifton, N.J.)　Vol. 751　p. 491-502　2011/10/04　Part of collection (book)

Cell adhesion behavior on the phase separated biointerface adsorbed/nonadsorbed protein regulated by nanoscale

Takai Madoka, Shibayama Takashi, Seo Ji Hun, Ishihara Kazuhiko

Kobunshi　Vol. 60　No. 10　p. 736-738　2011/10/01

Methacrylate polymer layers bearing poly(ethylene oxide) and phosphorylcholine side chains as non-fouling surfaces

Feng Wei, Gao Xiang, McClung Glenn, Zhu Shiping, Ishihara Kazuhiko, Brash John L

Acta Biomaterialia　Vol. 7　No. 10　p. 3692-3699　2011/10/01　Research paper (scientific journal)

Surface functionarization of polydimethylsiloxaneby photo-induced polymerization of 2-methacryloyloxyethyl phosphorylcholine for bio devices

Takai Madoka, Shirai Takanori, Ishihara Kazuhiko

Journal of Photopolymer Science and Technology　Vol. 24　No. 5　p. 597-602　2011/09/28　Research paper (scientific journal)

Cartilage-mimicking, Super Lubricious Bearing Surface Extends Longevity of Artificial Joint Replacements

KYOMOTO Masayuki, MORO Toru, ISHIHARA Kazuhiko

J. Surf. Sci. Soc. Jpn.　Vol. 32　No. 9　p. 557-562　2011/09/10

24-hour wound-healing in vitro model using a Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer

Atomi Yoriko, Ohto-Fujita Eri, Konno Tomohiro, Shimizu Miho, Ishihara Kazuhiko, Sugitate Toshihiro, Miyake Jun, Yoshimura Kotaro, Taniwaki Kaori, Sakurai Takashi, Hasebe Yukio

Journal of Investigative Dermatology　Vol. 131　p. S32-S32　2011/09

Physicochemical delivery of amphiphilic copolymers to specific organelles

Kojima Ryo, Kasuya Maria, Carmelita Z, Ishihara Kazuhiko, Hatanaka Kenichi

Polymer Journal　Vol. 43　No. 8　p. 718-722　2011/08/01　Research paper (scientific journal)

Cartilage-mimicking, high-density brush structure improves wear resistance of crosslinked polyethylene

Kyomoto Masayuki, Moro Toru, Takatori Yoshio, Kawaguchi Hiroshi, Ishihara Kazuhiko

Clinical Orthopaedics and Related Research　Vol. 469　No. 8　p. 2327-2336　2011/08/01　Research paper (scientific journal)

Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts

Ohto-Fujita Eri, Konno Tomohiro, Shimizu Miho, Ishihara Kazuhiko, Sugitate Toshihiro, Miyake Jun, Yoshimura Kotaro, Taniwaki Kaori, Sakurai Takashi, Hasebe Yukio, Atomi Yoriko

Cell and Tissue Research　Vol. 345　No. 1　p. 177-190　2011/07/01　Research paper (scientific journal)

Well-controlled cationic water-soluble phospholipid polymerDNA nanocomplexes for gene delivery

Ahmed Marya, Bhuchar Neha, Ishihara Kazuhiko, Narain Ravin

Bioconjugate Chemistry　Vol. 22　No. 6　p. 1228-1238　2011/06/15　Research paper (scientific journal)

Thermo-responsive behavior of hybrid core cross-linked polymer micelles with biocompatible shells

Goto Fumi, Ishihara Kazuhiko, Iwasaki Yasuhiko, Katayama Koichi, Enomoto Ryusuke, Yusa Shin Ichi

Polymer　Vol. 52　No. 13　p. 2810-2818　2011/06/08　Research paper (scientific journal)

In vivo evaluation of the "TinyPump" as a pediatric left ventricular assist device

Kitao Takashi, Ando Yusuke, Yoshikawa Masaharu, Kobayashi Mariko, Kimura Taro, Ohsawa Hideyuki, Machida Shinya, Yokoyama Naoyuki, Sakota Daisuke, Konno Tomohiro, Ishihara Kazuhiko, Takatani Setsuo

Artificial Organs　Vol. 35　No. 5　p. 543-553　2011/05/01　Research paper (scientific journal)

Active enhancement of anti-tumor effect by NF-kappa B inhibitor DHMEQ using PMBN conjugated with anti-EGFR antibody in human pancreatic adenocarcinoma cells in vivo and in vitro

Fujisaki Hiroto, Suzuki Keiichi, Matsuda Sachiko, Aiura Koichi, Itano Osamu, Ueda Masakazu, Umezawa Kazuo, Konno Tomohiro, Ishihara Kazuhiko, Kitagawa Yuko

CANCER RESEARCH　Vol. 71　2011/04/15

Effect of hydrophilic polymer conjugation on heat-induced conformational changes in a protein

Seo Ji Hun, Matsuno Ryosuke, Lee Yan, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Acta Biomaterialia　Vol. 7　No. 4　p. 1477-1484　2011/04/01　Research paper (scientific journal)

Quick and simple modification of a poly(dimethylsiloxane) surface by optimized molecular design of the anti-biofouling phospholipid copolymer

Seo Ji Hun, Shibayama Takashi, Takai Madoka, Ishihara Kazuhiko

Soft Matter　Vol. 7　No. 6　p. 2968-2976　2011/03/21　Research paper (scientific journal)

Significance of antibody orientation unraveled

Tajima Nobuyuki, Takai Madoka, Ishihara Kazuhiko

Analytical Chemistry　Vol. 83　No. 6　p. 1969-1976　2011/03/15　Research paper (scientific journal)

Detailed study of the reversible addition-fragmentation chain transfer polymerization and co-polymerization of 2-methacryloyloxyethyl phosphorylcholine

Bhuchar Neha, Deng Zhicheng, Ishihara Kazuhiko, Narain Ravin

Polymer Chemistry　Vol. 2　No. 3　p. 632-639　2011/03/01　Research paper (scientific journal)

Adhesion force of proteins against hydrophilic polymer brush surfaces

Inoue Yuuki, Nakanishi Tomoaki, Ishihara Kazuhiko

Reactive and Functional Polymers　Vol. 71　No. 3　p. 350-355　2011/03/01　Research paper (scientific journal)

Tissue response to poly(l-lactic acid)-based blend with phospholipid polymer for biodegradable cardiovascular stents

Kim Hyung Il, Ishihara Kazuhiko, Lee Seungbok, Seo Ji Hun, Kim Hye Young, Suh Dongwhan, Kim Min Uk, Konno Tomohiro, Takai Madoka, Seo Jeong Sun

Biomaterials　Vol. 32　No. 9　p. 2241-2247　2011/03/01　Research paper (scientific journal)

Novel polymer biomaterials and interfaces inspired from cell membrane functions

Ishihara Kazuhiko, Goto Yusuke, Takai Madoka, Matsuno Ryosuke, Inoue Yuuki, Konno Tomohiro

Biochimica et Biophysica Acta - General Subjects　Vol. 1810　No. 3　p. 268-275　2011/03/01

Integrated functional nanocolloids covered with artificial cell membranes for biomedical applications

Matsuno Ryosuke, Ishihara Kazuhiko

Nano Today　Vol. 6　No. 1　p. 61-74　2011/02/01

Electrical transport ability of nanostructured potassium-doped titanium oxide film

Lee So Yoon, Matsuno Ryosuke, Ishihara Kazuhiko, Takai Madoka

Applied Physics Express　Vol. 4　No. 2　2011/02/01　Research paper (scientific journal)

Reduction of peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair

Ishiyama Noriyuki, Moro Toru, Ohe Takashi, Miura Toshiki, Ishihara Kazuhiko, Konno Tomohiro, Ohyama Tadashi, Kimura Mizuna, Kyomoto Masayuki, Saito Taku, Nakamura Kozo, Kawaguchi Hiroshi

Journal of Bone and Joint Surgery - Series A　Vol. 93　No. 2　p. 142-149　2011/01/19　Research paper (scientific journal)

Bioinspired phospholipid polymer for improvement of biofouling on titanium alloy substrate

Ye Yao, Kyoko Fukazawa, Nan Huang, Kazuhiko Ishihara

Transactions of the Materials Research Society of Japan　Vol. 36　No. 4　p. 573-576　2011　Research paper (scientific journal)

Spontaneous Formation of a Hydrogel Composed of Water-Soluble Phospholipid Polymers Grafted with Enantiomeric Oligo(lactic acid) Chains

Kimiaki Takami, Junji Watanabe, Madoka Takai, Kazuhiko Ishihara

Journal of Biomaterials Science, Polymer Edition　Vol. 22　No. 1　p. 77-89　2011/01/01　Research paper (scientific journal)

Quantum dots covered with pH responsive and biocompatible phospholipid polymer for trafficking in endocytosis process

Kouichi Masuda, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jan　Vol. 36　No. 2　p. 265-268　2011

Spatial distribution of intraperitoneally administrated paclitaxel nanoparticles solubilized with poly (2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) in peritoneal metastatic nodules

Kamei Takao, Kitayama Joji, Yamaguchi Hironori, Soma Daisuke, Emoto Shigenobu, Konno Tomohiro, Ishihara Kazuhiko, Ishigami Hironori, Kaisaki Shoichi, Nagawa Hirokazu

Cancer Science　Vol. 102　No. 1　p. 200-205　2011/01/01　Research paper (scientific journal)

Spontaneous formation of a hydrogel composed of water-soluble phospholipid polymers grafted with enantiomeric oligo(lactic acid) chains

Takami Kimiaki, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 22　No. 1-3　p. 77-89　2011/01/01　Research paper (scientific journal)

Cell-based toxin screening integrated with a cell-sustainable hydrogel on chip for onsite and portable applications

Xu Y, Jang K, Mawatari K, Konno T, Ishihara K, Kitamori T

p. 1499-1501　2010/12/01

The biological performance of cell-containing phospholipid polymer hydrogels in bulk and microscale form

Xu Yan, Jang Kihoon, Konno Tomohiro, Ishihara Kazuhiko, Mawatari Kazuma, Kitamori Takehiko

Biomaterials　Vol. 31　No. 34　p. 8839-8846　2010/12/01　Research paper (scientific journal)

Simple and functional modification of PDMS surface for microchannel electropheresis

Shirai Takanori, Takai Madoka, Ishihara Kazuhiko

p. 1946-1948　2010/12/01

リン脂質ポリマーの非エンドサイトーシス細胞膜透過とオルガネラ局在

合田 達郎, 石原 一彦, 宮原 裕二

日本バイオマテリアル学会大会予稿集　Vol. 32回　p. 125-125　2010/11

Direct cell-membrane penetration using amphipathic polyphosphobetaines

Goda T, Ishihara K, Miyahara Y

European Cells and Materials　Vol. 20　No. SUPPL.3　2010/11/01

Surface modification of SiO₂ microchannels with biocompatible polymer using supercritical carbon dioxide

Saito Tatsuro, Momose Takeshi, Hoshi Toru, Takai Madoka, Ishihara Kazuhiko, Shimogaki Yukihiro

Japanese Journal of Applied Physics　Vol. 49　No. 11　2010/11/01　Research paper (scientific journal)

Nanoforce measurement during protein adsorption to well-controlled polymer brush surfaces

Ishihara Kazuhiko, Nakanishi Tomoaki, Takai Madoka, Inoue Yuuki

European Cells and Materials　Vol. 20　No. SUPPL.3　2010/11/01

Reduction of protein adsorption on well-characterized polymer brush layers with varying chemical structures

Inoue Yuuki, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 81　No. 1　p. 350-357　2010/11/01　Research paper (scientific journal)

Single cell analysis based on functional phospholipid polymers

Konno T, Taniguchi K, Nishida H, Kambara H, Ishihara K

European Cells and Materials　Vol. 20　No. SUPPL.3　2010/11/01

Molecular-NANOintegrated surface for selective protein recognition by molecular imprinting concept

Fukazawa Kyoko, Li Qiang, Seeger Stefan, Ishihara Kazuhiko

European Cells and Materials　Vol. 20　No. SUPPL.3　2010/11/01　Research paper (scientific journal)

Monitoring of initial cell adhesion process on nanometer-scaled and organized surfaces

Kitagawa Tomomi, Inoue Yuuki, Takai Madoka, Ishihara Kazuhiko

European Cells and Materials　Vol. 20　No. SUPPL.3　2010/11/01

Single-cell attachment and culture method using a photochemical reaction in a closed microfluidic system

Jang Kihoon, Xu Yan, Tanaka Yo, Sato Kae, Mawatari Kazuma, Konno Tomohiro, Ishihara Kazuhiko, Kitamori Takehiko

Biomicrofluidics　Vol. 4　No. 3　2010/10/19　Research paper (scientific journal)

Photo-induced functionalization on biomaterials surfaces

Ishihara Kazuhiko, Kyomoto Masayuki

Journal of Photopolymer Science and Technology　Vol. 23　No. 2　p. 161-166　2010/09/30　Research paper (scientific journal)

Simple surface modification of a titanium alloy with silanated zwitterionic phosphorylcholine or sulfobetaine modifiers to reduce thrombogenicity

Ye Sang Ho, Johnson Carl A, Woolley Joshua R, Murata Hironobu, Gamble Lara J, Ishihara Kazuhiko, Wagner William R

Colloids and Surfaces B: Biointerfaces　Vol. 79　No. 2　p. 357-364　2010/09/01　Research paper (scientific journal)

Surface grafting of biocompatible phospholipid polymer MPC provides wear resistance of tibial polyethylene insert in artificial knee joints

Moro T, Takatori Y, Kyomoto M, Ishihara K, Saiga K, Nakamura K, Kawaguchi H

Osteoarthritis and Cartilage　Vol. 18　No. 9　p. 1174-1182　2010/09/01　Research paper (scientific journal)

Simple synthesis of a library of zwitterionic surfactants via michael-type addition of methacrylate and alkane thiol compounds

Matsuno Ryosuke, Takami Kimiaki, Ishihara Kazuhiko

Langmuir　Vol. 26　No. 16　p. 13028-13032　2010/08/17　Research paper (scientific journal)

An efficient surface modification using 2-methacryloyloxyethyl phosphorylcholine to control cell attachment via photochemical reaction in a microchannel

Jang Kihoon, Sato Kae, Tanaka Yo, Xu Yan, Sato Moritoshi, Nakajima Takahiro, Mawatari Kazuma, Konno Tomohiro, Ishihara Kazuhiko, Kitamori Takehiko

Lab on a Chip - Miniaturisation for Chemistry and Biology　Vol. 10　No. 15　p. 1937-1945　2010/08/07　Research paper (scientific journal)

2-Methacryloyloxyethyl phosphorylcholine polymer (MPC)-coating improves the transfection activity of GALA-modified lipid nanoparticles by assisting the cellular uptake and intracellular dissociation of plasmid DNA in primary hepatocytes

Ukawa Masami, Akita Hidetaka, Masuda Tomoya, Hayashi Yasuhiro, Konno Tomohiro, Ishihara Kazuhiko, Harashima Hideyoshi

Biomaterials　Vol. 31　No. 24　p. 6355-6362　2010/08/01　Research paper (scientific journal)

A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions

Xu Yan, Sato Kae, Mawatari Kazuma, Konno Tomohiro, Jang Kihoon, Ishihara Kazuhiko, Kitamori Takehiko

Advanced Materials　Vol. 22　No. 28　p. 3017-3021　2010/07/27　Research paper (scientific journal)

Control of surface modification uniformity inside small-diameter polyethylene/poly(vinyl acetate) composite tubing prepared with supercritical carbon dioxide

Hoshi Toru, Sawaguchi Takashi, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Journal of Materials Chemistry　Vol. 20　No. 23　p. 4897-4904　2010/06/07　Research paper (scientific journal)

Phospholipid polymer biointerfaces for lab-on-a-chip devices

Xu Yan, Takai Madoka, Ishihara Kazuhiko

Annals of Biomedical Engineering　Vol. 38　No. 6　p. 1938-1953　2010/06/01　Research paper (scientific journal)

Cell-driven three-dimensional manipulation of microparts for a microassembly

Hoshino Takayuki, Higashi Ayako, Konno Tomohiro, Ishihara Kazuhiko, Morishima Keisuke

Japanese Journal of Applied Physics　Vol. 49　No. 6 PART 2　2010/06/01　Research paper (scientific journal)

The prevention of peritendinous adhesions by a phospholipid polymer hydrogel formed in situ by spontaneous intermolecular interactions

Ishiyama Noriyuki, Moro Toru, Ishihara Kazuhiko, Ohe Takashi, Miura Toshiki, Konno Tomohiro, Ohyama Tadashi, Kimura Mizuna, Kyomoto Masayuki, Nakamura Kozo, Kawaguchi Hiroshi

Biomaterials　Vol. 31　No. 14　p. 4009-4016　2010/05/01　Research paper (scientific journal)

Super-hydrophilic silicone hydrogels with interpenetrating poly(2-methacryloyloxyethyl phosphorylcholine) networks

Shimizu Takanori, Goda Tatsuro, Minoura Norihiko, Takai Madoka, Ishihara Kazuhiko

Biomaterials　Vol. 31　No. 12　p. 3274-3280　2010/04/01　Research paper (scientific journal)

Selection of highly osteogenic and chondrogenic cells from bone marrow stromal cells in biocompatible polymer-coated plates

Liu G, Iwata K, Ogasawara T, Watanabe J, Fukazawa K, Ishihara K, Asawa Y, Fujihara Y, Chung U. L, Moro T, Takatori Y, Takato T, Nakamura K, Kawaguchi H, Hoshi K

Journal of Biomedical Materials Research - Part A　Vol. 92　No. 4　p. 1273-1282　2010/03/15　Research paper (scientific journal)

Stabilization of phospholipid polymer surface with three-dimensional nanometer-scaled structure for highly sensitive immunoassay

Nishizawa Kazuki, Takai Madoka, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 77　No. 2　p. 263-269　2010/03/02　Research paper (scientific journal)

Biocompatible polymer assembly on metal surfaces

Ishihara K, Choi J

Metals for Biomedical Devices　p. 283-302　2010/03/01　Part of collection (book)

Feasibility study of introducing redox property by modification of pmbn polymer for biofuel cell applications

Yu Eileen Hao, Himuro Yoko, Takai Madoka, Ishihara Kazuhiko

Applied Biochemistry and Biotechnology　Vol. 160　No. 4　p. 1094-1101　2010/02/01　Research paper (scientific journal)

Self-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine) on poly(ether-ether-ketone)

Kyomoto Masayuki, Moro Toru, Takatori Yoshio, Kawaguchi Hiroshi, Nakamura Kozo, Ishihara Kazuhiko

Biomaterials　Vol. 31　No. 6　p. 1017-1024　2010/02/01　Research paper (scientific journal)

Development of cell/transistor interface for real-time and noninvasive monitoring of potassium ion release based on apoptosis using biologically-coupled field effect transistor

Taiichiro Murakami, Toshiya Sakata, Akira Matsumoto, Madoka Takai, Kazuhiko Ishihara, Yuji Miyahara

Transactions of the Materials Research Society of Japan　Vol. 35　p. 255-258　2010

Preparation of Poly(2-methaycryloyloxyethylphosphorylcholine)/hydroxyapatite Hybrid Matrix

Yasuo Toyomoto, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 35　No. 1　p. 123-126　2010

Effect of Well-Defined Polymer Brush Surface on Protein Adsorption Behavior

Tomoaki Nakanishi, Yuuki Inoue, Ryosuke Matsuno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 35　No. 1　p. 135-138　2010

Novel Cytocompatible Intracellular pH-imaging Fluorescence Probe Composed of Quantum Dot and Phospholipid Polymer

Kouichi Masuda, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 35　No. 1　p. 147-150　2010

Control of cell function on a phospholipid polymer having phenylboronic acid moiety

Saito Aya, Konno Tomohiro, Ikake Hiroki, Kurita Kimio, Ishihara Kazuhiko

Biomedical Materials　Vol. 5　No. 5　2010/01/01　Research paper (scientific journal)

Lubricity and stability of poly(2-methacryloyloxyethyl phosphorylcholine) polymer layer on Co-Cr-Mo surface for hemi-arthroplasty to prevent degeneration of articular cartilage

Kyomoto Masayuki, Moro Toru, Saiga Ken Ichi, Miyaji Fumiaki, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Biomaterials　Vol. 31　No. 4　p. 658-668　2010/01/01　Research paper (scientific journal)

Muscle-powered nano mechanical system assembled by optical tweezers

Hoshino Takayuki, Kuroda Hiroshi, Konno Tomohiro, Ishihara Kazuhiko, Kometani Reo, Morishima Keisuke

2009 9TH IEEE CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO)　p. 636-639　2009/12/01　Research paper (international conference proceedings)

Superlubricious surface mimicking articular cartilage by grafting poly(2-methacryloyloxyethyl phosphorylcholine) on orthopaedic metal bearings

Kyomoto Masayuki, Moro Toru, Iwasaki Yasuhiko, Miyaji Fumiaki, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 91　No. 3　p. 730-741　2009/12/01　Research paper (scientific journal)

Graft linker immobilization for spatial control of protein immobilization inside fused microchips

Shirai Kentaro, Renberg Björn, Sato Kae, Mawatari Kazuma, Konno Tomohiro, Ishihara Kazuhiko, Kitamori Takehiko

Electrophoresis　Vol. 30　No. 24　p. 4251-4255　2009/12/01　Research paper (scientific journal)

Live-cell-driven insertion of a nanoneedle

Hoshino Takayuki, Konno Tomohiro, Ishihara Kazuhiko, Morishima Keisuke

Japanese Journal of Applied Physics　Vol. 48　No. 10 Part 1　p. 1070021-1070026　2009/12/01　Research paper (scientific journal)

Bioinspired biomaterials for soft contact lenses

Goda T, Shimizu T, Ishihara K

Biomaterials and Regenerative Medicine in Ophthalmology　p. 263-279　2009/12/01　Part of collection (book)

Biodegradable polymer films for releasing nanovehicles containing sirolimus Biodegradable polymer containing nanovehicles with sirolimus Hyung Il Kim et al.

Kim Hyung Il, Takai Madoka, Konno Tomohiro, Matsuno Ryosuke, Ishihara Kazuhiko

Drug Delivery　Vol. 16　No. 4　p. 183-188　2009/11/09　Research paper (scientific journal)

Surface modification of a titanium alloy with a phospholipid polymer prepared by a plasma-induced grafting technique to improve surface thromboresistance

Ye Sang Ho, Johnson Carl A, Woolley Joshua R, Oh Heung Il, Gamble Lara J, Ishihara Kazuhiko, Wagner William R

Colloids and Surfaces B: Biointerfaces　Vol. 74　No. 1　p. 96-102　2009/11/01　Research paper (scientific journal)

Progress of research in osteoarthritis. Invention of longer lasting artificial joints

Moro Toru, Takatori Yoshio, Ishihara Kazuhiko, Kyomoto Masayuki, Nakamura Kozo, Kawaguchi Hiroshi

Clinical calcium　Vol. 19　No. 11　p. 1629-1637　2009/11/01

Cell adhesion on phase-separated surface of block copolymer composed of poly(2-methacryloyloxyethyl phosphorylcholine) and poly(dimethylsiloxane)

Seo Ji Hun, Matsuno Ryosuke, Takai Madoka, Ishihara Kazuhiko

Biomaterials　Vol. 30　No. 29　p. 5330-5340　2009/10/01　Research paper (scientific journal)

Intraperitoneal administration of paclitaxel solubilized with poly(2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) for peritoneal dissemination of gastric cancer

Soma Daisuke, Kitayama Joji, Konno Tomohiro, Ishihara Kazuhiko, Yamada Jun, Kamei Takao, Ishigami Hironori, Kaisaki Shoichi, Nagawa Hirokazu

Cancer Science　Vol. 100　No. 10　p. 1979-1985　2009/10/01　Research paper (scientific journal)

Development of a method to evaluate caspase-3 activity in a single cell using a nanoneedle and a fluorescent probe

Kihara Takanori, Nakamura Chikashi, Suzuki Miho, Han Sung Woong, Fukazawa Kyoko, Ishihara Kazuhiko, Miyake Jun

Biosensors and Bioelectronics　Vol. 25　No. 1　p. 22-27　2009/09/15　Research paper (scientific journal)

Characterization of swollen structure of high-density polyelectrolyte brushes in salt solution by neutron reflectivity

Kobayashi Motoyasu, Terayama Yuki, Hino Masahiro, Ishihara Kazuhiko, Takahara Atsushi

Journal of Physics: Conference Series　Vol. 184　2009/09/08　Research paper (international conference proceedings)

Synthesis of amphiphilic copolymers by soap-free interface-mediated polymerization

Kojima Ryo, Kasuya Maria, Carmelita Z, Ishihara Kazuhiko, Hatanaka Kenichi

Polymer Journal　Vol. 41　No. 5　p. 370-373　2009/08/10　Research paper (scientific journal)

Effects of mobility/immobility of surface modification by 2-methacryloyloxyethyl phosphorylcholine polymer on the durability of polyethylene for artificial joints

Kyomoto Masayuki, Moro Toru, Miyaji Fumiaki, Hashimoto Masami, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 90　No. 2　p. 362-371　2009/08/01　Research paper (scientific journal)

Preparation of electrospun poly(l-lactide-co-caprolactone-co-glycolide)/phospholipid polymer/rapamycin blended fibers for vascular application

Kim Hyung Il, Matsuno Ryosuke, Seo Ji Hun, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Current Applied Physics　Vol. 9　No. 4 SUPPL.　p. E249-E251　2009/07/01　Research paper (scientific journal)

Solubilization of quantum dot with new double functional reversible addition-fragmentation chain transfer reagents

Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Current Applied Physics　Vol. 9　No. 4 SUPPL.　p. E284-E286　2009/07/01　Research paper (scientific journal)

Smart controlled preparation of multilayered hydrogel for releasing bioactive molecules

Choi Jiyeon, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Current Applied Physics　Vol. 9　No. 4 SUPPL.　p. E259-E262　2009/07/01　Research paper (scientific journal)

Preparation of nano-structured titanium oxide film for biosensor substrate by wet corrosion process

Lee So Yoon, Takai Madoka, Kim Hyun Min, Ishihara Kazuhiko

Current Applied Physics　Vol. 9　No. 4 SUPPL.　p. E266-E269　2009/07/01　Research paper (scientific journal)

Precise design of surface nano-texture and surface chemistry of polymeric solids

Honda Koji, Yamaguchi Hiroki, Kimura Taichi, Terayama Yuki, Kobayashi Motoyasu, Morita Masamichi, Sasaki Sono, Sakata Osami, Torikai Naoya, Ishihara Kazuhiko, Takahara Atsushi

Composite Interfaces　Vol. 16　No. 4　p. 519-533　2009/07/01　Research paper (scientific journal)

Bioinspired interface for nanobiodevices based on phospholipid polymer chemistry

Ishihara Kazuhiko, Takai Madoka

Journal of the Royal Society Interface　Vol. 6　No. SUPPL. 3　p. S279-S291　2009/06/06

Bioabsorbable material-containing phosphorylcholine group-rich surfaces for temporary scaffolding of the vessel wall

Kim Hyung Il, Takai Madoka, Ishihara Kazuhiko

Tissue Engineering - Part C: Methods　Vol. 15　No. 2　p. 125-133　2009/06/01　Research paper (scientific journal)

Selective targeting by preS1 domain of hepatitis B surface antigen conjugated with phosphorylcholine-based amphiphilic block copolymer micelles as a biocompatible, drug delivery carrier for treatment of human hepatocellular carcinoma with paclitaxel

Miyata Ryohei, Ueda Masakazu, Jinno Hiromitsu, Konno Tomohiro, Ishihara Kazuhiko, Ando Nobutoshi, Kitagawa Yuko

International Journal of Cancer　Vol. 124　No. 10　p. 2460-2467　2009/05/15　Research paper (scientific journal)

Structure and surface properties of high-density polyelectrolyte brushes at the interface of aqueous solution

Kobayashi Motoyasu, Yamaguchi Hiroki, Terayama Yuki, Wang Zhe, Ishihara Kazuhiko, Hino Masahiro, Takahara Atsushi

Macromolecular Symposia　Vol. 279　No. 1　p. 79-87　2009/05/01　Research paper (international conference proceedings)

RAFT synthesis and stimulus-induced self-assembly in water of copolymers based on the biocompatible monomer 2-(Methacryloyloxy)ethyl phosphorylcholine

Yu Bing, Lowe Andrew B, Ishihara Kazuhiko

Biomacromolecules　Vol. 10　No. 4　p. 950-958　2009/04/13　Research paper (scientific journal)

Protein adsorption resistance and oxygen permeability of chemically crosslinked phospholipid polymer hydrogel for ophthalmologic biomaterials.

Tatsuro Goda, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Journal of Biomedical Materials Research Part B: Applied Biomaterials　Vol. 89　No. 1　p. 184-190　2009/04　Research paper (scientific journal)

Development of targeted therapy with paclitaxel incorporated into EGF-conjugated nanoparticles

Shimada Toshiyuki, Ueda Masakazu, Jinno Hiromitsu, Chiba Naokazu, Wada Masahiro, Watanabe Junji, Ishihara Kazuhiko, Kitagawa Yuko

Anticancer Research　Vol. 29　No. 4　p. 1009-1014　2009/04/01　Research paper (scientific journal)

Protein adsorption resistance and oxygen permeability of chemically crosslinked phospholipid polymer hydrogel for ophtnalmologie biomaterials

Goda Tatsuro, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part B Applied Biomaterials　Vol. 89　No. 1　p. 184-190　2009/04/01

Selection of highly osteogenic and chondrogenic cells from bone marrow stromal cells in biocompatible polymer-coated plates

Guangyao Liu, Kumiko Iwata, Toru Ogasawara, Junji Watanabe, Kyoko Fukazawa, Kazuhiko Ishihara, Yukiyo Asawa, Yuko Fujihara, Ung-il. Chung, Toru Moro, Yoshio Takatori, Tsuyoshi Takato, Kozo Nakamura, Hiroshi Kawaguchi, Kazuto Hoshi

Journal of Biomedical Materials Research Part A　Vol. 92A　No. 4　p. 1273-1282　2009/03/27　Research paper (scientific journal)

Self-initiated surface graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on poly(ether ether ketone) by photoirradiation

Kyomoto Masayuki, Ishihara Kazuhiko

ACS Applied Materials and Interfaces　Vol. 1　No. 3　p. 537-542　2009/03/25　Research paper (scientific journal)

Suppression of protein adsorption on a charged phospholipid polymer interface

Xu Yan, Takai Madoka, Ishihara Kazuhiko

Biomacromolecules　Vol. 10　No. 2　p. 267-274　2009/02/09　Research paper (scientific journal)

Poly(vinylferrocene-co-2-hydroxyethyl methacrylate) mediator as immobilized enzyme membrane for the fabrication of amperometric glucose sensor

Himuro Yoko, Takai Madoka, Ishihara Kazuhiko

Sensors and Actuators, B: Chemical　Vol. 136　No. 1　p. 122-127　2009/02/02　Research paper (scientific journal)

High-Sensitive Analysis of Oligopeptide-Induced Cell Penetration Using Phospholipid Polymer Nanoparticles Containing Quantum Dots

Yusuke Goto, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 34　No. 2　p. 189-192　2009

A Novel Interface for High-Sensitive Immunoassay Using Orientation Controlled Protein A and Non-biofouling Phospholipid Polymer Surface

Nobuyuki Tajima, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 34　No. 2　p. 205-208　2009

Antithrombogenic Surface Constructed by Block-type Phospholipid Polymer and Segmented Polyurethane

Yoshiharu Asanuma, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 34　No. 2　p. 197-200　2009

Single ceell driven nano tweezers

Hoshino Takayuki, Kuroda Hiroshi, Kometan Reo, Konno Tomohiro, Ishihara Kazuhiko, Morishima Keisuke

p. 1530-1532　2009/01/01

Guiding principle of biocompatible polymer surface modification for PDMS microfluidic chips

Takai Madoka, Nishizawa Kazuki, Hirozane Yumiko, Ishihara Kazuhiko

p. 1560-1562　2009/01/01

Microchip immunoassay with 3D nanostructured phospholipid polymer biointerface

Nishizawa Kazuki, Tkai Madoka, Ishihara Kazuhiko

p. 1584-1586　2009/01/01

An on-chip living cell bank

Xu Yan, Sato Kae, Konno Tomohiro, Ishihara Kazuhiko, Kitamori Takehiko

p. 1952-1954　2009/01/01

Phospholipid polymer-modified field effect transistor for sensitive detection of biomolecular recognition

Futamura Koji, Matsumoto Akira, Sakata Toshiya, Ishihara Kazuhiko, Miyahara Yuji

p. 1557-1559　2009/01/01

Controllable nanostructured surface modification on quantum dot for biomedical application in aqueous medium

Matsuno Ryosuke, Goto Yusuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Journal of Nanoscience and Nanotechnology　Vol. 9　No. 1　p. 358-365　2009/01/01　Research paper (scientific journal)

Non fluidic cell culture medium for maintaining Ce 11 functions; cell-container base d on reversible phospholipid polymer hydrogel with highly cytocompatibility

Konno Tomohiro, Ishihara Kazuhiko

2008/12/01

Hemocompatible/cell adhesive hetero surface polymer membranes

Kawai Hirotaka, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Surface immobilization of biocompatible phospholipid polymer multilayered hydrogel on titanium alloy

Choi Jiyeon, Konno Tomohiro, Matsuno Ryosuke, Takai Madoka, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 67　No. 2　p. 216-223　2008/12/01　Research paper (scientific journal)

Multilayered phospholipid polymer hydrogels for regulating cell functions by self-tuning bioactive agent concentration

Choi Jiyeon, Konno Tomohiro, Matsuno Ryosuke, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Well defined phospholipid polymer grafting over quantum dot using RAFT polymerization

Matsuno Ryosuke, Goto Yusuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Protein resistance on polymer-grafted PDMS using photoinitiation performance of ketones

Goda Tatsuro, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

A nano-needle interface self-assembled by using cell migration for recording intracellular activity

Hoshino Takayuki, Konno Tomohiro, Ishihara Kazuhiko, Morishima Keisuke

2008 2ND IEEE RAS & EMBS INTERNATIONAL CONFERENCE ON BIOMEDICAL ROBOTICS AND BIOMECHATRONICS (BIOROB 2008), VOLS 1 AND 2　p. 506-510　2008/12/01　Research paper (international conference proceedings)

New nanocomposite biomaterials controlling surface and bulk properties using supercritical carbon dioxide

Hoshi Tora, Sawagushi Takashi, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

p. 58-64　2008/12/01

The end group modification of phospholipid polymer brush grafted on ferric oxide nanoparticles for diagnostics

Matsuno Ryosuke, Ishihara Kazuhiko

p. 1-5　2008/12/01

Nanometer-scale high lubricious surface modification extends the durability of artificial joint

Kyomoto Masayuki, Moro Toru, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

2008/12/01

Quick providing of hydrophilic and protein adsorption resistant surface by phospholipid polymers

Futamura Koji, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Simple modified biomimetic silicone surface by selective interaction with amphiphilic block copolymer

Seo Ji Hun, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Improved protein adsorption on soft contact lenses treated with phospholipid polymers

Shimizu Takanori, Goda Tatsuro, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Suppressing bioadsorption on electrokinetic microdevice by a charged phospholipid polymer biointerface

Xu Yan, Takai Madoka, Konno Tomohiro, Ishihara Kazuhiko

2008/12/01

Micropatterned biorecognition surfaces on nonbiofouling polymer by living radical photopolymerization for high sensitivity biosensing

Takai Madoka, Sibarani James, Ishihara Kazuhiko

p. 6-12　2008/12/01

Phospholipid polymer nanoparticles bearing quantum dots for affinity bioimaging of cell-protein interaction

Goto Yusuke, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Grafting of biocompatible polymer on the liner surface for extending longevity of artificial hip joints

Moro Toru, Takatori Yoshio, Ishihara Kazuhiko, Konno Tomohiro, Kyomoto Masayuki, Yamamoto Motoi, Karita Tatsuro, Ito Hideya, Nakamura Kozo, Kawaguchi Hiroshi

2008/12/01

Multi-biofunctional phospholipid block polymer alloys with segmented polyurethane

Asanuma Yoshiharu, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2008/12/01

Synthesis and properties of segmented poly(urethane-urea)s containing phosphorylcholine moiety in the side-chain

Nagase Yu, Nakajima Satoru, Oku Masataka, Iwasaki Yasuhiko, Ishihara Kazuhiko

Polymer Journal　Vol. 40　No. 12　p. 1149-1156　2008/12/01　Research paper (scientific journal)

Bioinspired polymer surfaces for nanodevices and nanomedicine

Ishihara Kazuhiko, Nishizawa Kazuki, Goto Yusuke, Takai Madoka

BIOMEDICAL APPLICATIONS OF SMART MATERIALS, NANOTECHNOLOGY AND MICRO/NANO ENGINEERING　Vol. 57　p. 5-14　2008/12/01　Research paper (international conference proceedings)

Cytocompatible phospholipid polymer hydrogel scaffold with tunable cell capturing ligand density

Ishihara Kazuhiko, Maeta Eri, Konno Tomohiro, Takai Madoka

2008/12/01

Protein adsorption resistant surface on polymer composite based on 2D- and 3D-controlled grafting of phospholipid moieties

Hoshi Toru, Matsuno Ryosuke, Sawaguchi Takashi, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Applied Surface Science　Vol. 255　No. 2　p. 379-383　2008/11/15　Research paper (scientific journal)

Lubrication properties of surfaces with superhydrophilic polymer brushes

Kobayashi Motoyasu, Kaido Masataka, Suzuki Atsushi, Ishihara Kazuhiko, Takahara Atsushi

Japanese Journal of Tribology　Vol. 53　No. 3　p. 259-266　2008/11/05

Artificial cell membrane-covered nanoparticles embedding quantum dots as stable and highly sensitive fluorescence bioimaging probes

Goto Yusuke, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Biomacromolecules　Vol. 9　No. 11　p. 3252-3257　2008/11/01　Research paper (scientific journal)

Hydration of phosphorylcholine groups attached to highly swollen polymer hydrogels studied by thermal analysis

Morisaku Toshinori, Watanabe Junji, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Polymer　Vol. 49　No. 21　p. 4652-4657　2008/10/06　Research paper (scientific journal)

Rapid development of hydrophilicity and protein adsorption resistance by polymer surfaces bearing phosphorylcholine and naphthalene groups

Futamura Koji, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Langmuir　Vol. 24　No. 18　p. 10340-10344　2008/09/16　Research paper (scientific journal)

Establishing ultimate biointerfaces covered with phosphorylcholine groups

Watanabe Junji, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 65　No. 2　p. 155-165　2008/09/01　Research paper (scientific journal)

Dimensions of a free linear polymer and polymer immobilized on silica nanoparticles of a zwitterionic polymer in aqueous solutions with various ionic strengths

Matsuda Yasuhiro, Kobayashi Motoya, Annaka Masahiko, Ishihara Kazuhiko, Takahara Atsushi

Langmuir　Vol. 24　No. 16　p. 8772-8778　2008/08/19　Research paper (scientific journal)

POLY 508-Polymeric nanoparticles with artificial cell membrane surface for high-affinity separation of proteins

Ishihara Kazuhiko, Goto Yusuke, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY　Vol. 236　2008/08/17

Lubrication properties of surfaces with super-hydrophilic polymer brushes

Kobayashi Motoyasu, Kaido Masataka, Suzuki Atsushi, Ishihara Kazuhiko, Takahara Atsushi

Toraibarojisuto/Journal of Japanese Society of Tribologists　Vol. 53　No. 6　p. 357-362　2008/08/12　Research paper (scientific journal)

Effect of 2-methacryloyloxyethyl phosphorylcholine concentration on photo-induced graft polymerization of polyethylene in reducing the wear of orthopaedic bearing surface

Kyomoto Masayuki, Moro Toru, Miyaji Fumiaki, Hashimoto Masami, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 86　No. 2　p. 439-447　2008/08/01　Research paper (scientific journal)

UCST-type cononsolvency behavior of poly(2-methacryloxyethyl phosphorylcholine) in the mixture of water and ethanol

Matsuda Yasuhiro, Kobayashi Motoyasu, Annaka Masahiko, Ishihara Kazuhiko, Takahara Atsushi

Polymer Journal　Vol. 40　No. 5　p. 479-483　2008/07/17　Research paper (scientific journal)

Antithrombogenic properties of a monopivot magnetic suspension centrifugal pump for circulatory assist

Yamane Takashi, Maruyama Osamu, Nishida Masahiro, Kosaka Ryo, Chida Takahiro, Kawamura Hiroshi, Kuwana Katsuyuki, Ishihara Kazuhiko, Sankai Yoshiyuki, Matsuzaki Mio, Shigeta Osamu, Enomoto Yoshiharu, Tsutsui Tatsuo

Artificial Organs　Vol. 32　No. 6　p. 484-489　2008/06/01　Research paper (scientific journal)

Graft copolymerization of 2-methacryloyloxyethyl phosphorylcholine to cellulose in homogeneous media using atom transfer radical polymerization for providing new hemocompatible coating materials

Yan Lifeng, Ishihara Kazuhiko

Journal of Polymer Science, Part A: Polymer Chemistry　Vol. 46　No. 10　p. 3306-3313　2008/05/15　Research paper (scientific journal)

Photografting of 2-methacryloyloxyethyl phosphorylcholine from polydimethylsiloxane

Goda Tatsuro, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 63　No. 1　p. 64-72　2008/05/01　Research paper (scientific journal)

Enhanced wear resistance of orthopaedic bearing due to the cross-linking of poly(MPC) graft chains induced by gamma-ray irradiation (Journal of Biomedical Materials Research - Part B Applied Biomaterials (2008) 82B, (320-327) DOI

Kyomoto Masayuki, Moro Toru, Miyaji Fumiaki, Konno Tomohiro, Hashimoto Masami, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part B Applied Biomaterials　Vol. 85　No. 1　2008/04/01　Research paper (scientific journal)

Surface tethering of phosphorylcholine groups onto poly(dimethylsiloxane) through swelling-deswelling methods with phospholipids moiety containing ABA-type block copolymers

Seo Ji Hun, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Biomaterials　Vol. 29　No. 10　p. 1367-1376　2008/04/01　Research paper (scientific journal)

Polymer composite biomaterials from polyethylene/poly(vinyl acetate) prepared in supercritical carbon dioxide and their bulk and surface characterization

Hoshi Toru, Sawaguchi Takashi, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Journal of Supercritical Fluids　Vol. 44　No. 3　p. 391-399　2008/04/01　Research paper (scientific journal)

Cell-container prepared with cytocompatible phospholipid polymers for cell and tissue engineering

Konno Tomohiro, Ishihara Kazuhiko

POLYMERS FOR BIOMEDICAL APPLICATIONS　Vol. 977　p. 336-345　2008/03/28　Research paper (international conference proceedings)

Polymer nanoparticles covered with phosphorylcholine groups and immobilized with antibody for high-affinity separation of proteins

Goto Yusuke, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Biomacromolecules　Vol. 9　No. 3　p. 828-833　2008/03/01　Research paper (scientific journal)

Functional biointerface for microfluidic devices using phospholipid polymers

Takai Madoka, Xu Yan, Sibarani James, Ishihara Kazuhiko

Kobunshi Ronbunshu　Vol. 65　No. 3　p. 228-234　2008/03/01　Research paper (scientific journal)

Enhanced wear resistance of orthopaedic bearing due to the cross-linking of poly(MPC) graft chains induced by gamma-ray irradiation

Masayuki Kyomoto, Toru Moro, Fumiaki Miyaji, Tomohiro Konno, Masami Hashimoto, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, Kazuhiko Ishihara

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS　Vol. 84B　No. 2　p. 320-327　2008/02　Research paper (scientific journal)

Prevention of biofilm formation with a coating of 2-methacryloyloxyethyl phosphorylcholine polymer

Fujii Kiyohisa, Matsumoto Hiroko N, Koyama Yoshihisa, Iwasaki Yasuhiko, Ishihara Kazuhiko, Takakuda Kazuo

Journal of Veterinary Medical Science　Vol. 70　No. 2　p. 167-173　2008/02/01　Research paper (scientific journal)

Enhanced wear resistance of orthopaedic bearing due to the cross-linking of poly(MPC) graft chains induced by gamma-ray irradiation

Kyomoto Masayuki, Moro Toru, Miyaji Fumiaki, Konno Tomohiro, Hashimoto Masami, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part B Applied Biomaterials　Vol. 84　No. 2　p. 320-327　2008/02/01

Single step diagnosis system using the FRET phenomenon induced by antibody-immobilized phosphorylcholine group-covered polymer nanoparticles

Watanabe Junji, Ishihara Kazuhiko

Sensors and Actuators, B: Chemical　Vol. 129　No. 1　p. 87-93　2008/01/29　Research paper (scientific journal)

ホスホリルコリン基含有芳香族ジアミンモノマーを用いたセグメント化ポリウレタン-ウレアの合成と性質

那川大輔, 堀口健二, 長瀬裕, 岩崎泰彦, 石原一彦

日本バイオマテリアルシンポジウム2008講演予稿集　Vol. P1-24　2008

新規ホスホリルコリン基含有ジアミンモノマーを用いた芳香族ポリアミドの合成と生体適合性、分岐鎖末端にホスホリルコリン基を含有するハイパーブランチ型芳香族ポリアミドの合成と性質

堀口健二, 下山田直矢, 長瀬 裕, 岩崎泰彦, 石原一彦

東海大学紀要工学部　Vol. 48　No. 1　p. 11-17　2008

Syntheses of a Novel Diamine Monomer and Aromatic Polyamides Containing Phosphorylcholine group

Kenji Horiguchi, Naoya Shimoyamada, Daisuke Nagawa, Yu Nagase, Yasuhiko Iwasaki, Kazuhiko Ishihara

Transactions of the Material Research Society of Japan　Vol. 33　No. 4　p. 1261-1264　2008

Enhanced wear resistance of orthopaedic bearing due to the cross-linking of poly(MPC) graft chains induced by gamma-ray irradiation (vol 84, pg 320, 2008)

Kyomoto Masayuki, Moro Toru, Miyaji Fumiaki, Konno Tomohiro, Hashimoto Masami, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Journal of Biomedical Materials Research Part B-Applied Biomaterials　Vol. 85B　No. 1　p. 301-301　2008

Differentiation Function of Embryonic Stem Cell Inducible Bio-interface Patterned by Photo-reactive Phospholipid Polymer

Taisuke Horie, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 33　No. 3　p. 811-814　2008　Research paper (international conference proceedings)

Nanoscale Structured Phospholipid Polymer Brush for Biointerface

Kitano Kazuhiko, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

TRANSACTIONS OF THE MATERIALS RESEARCH SOCIETY OF JAPAN, VOL 33, NO 3　Vol. 33　No. 3　p. 771-774　2008　Research paper (international conference proceedings)

Selective control of cell attachment in microchannel using photochemical reaction

Jang Kihoon, Sato Kae, Konno Tomohiro, Ishihara Kazuhiko, Kitamori Takehiko

p. 901-903　2008/01/01

Bioconjugated phospholipid polymer biointerface for enzyme-linked immunosorbent assay

Nishizawa Kazuki, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Biomacromolecules　Vol. 9　No. 1　p. 403-407　2008/01/01　Research paper (scientific journal)

Microchip analysis of cellular respiratory activity on PDMS membrane having gas permselective property

Shirai T, Sakata T, Takai M, Miyahara Y, Ishihara K

p. 546-548　2008/01/01

Cell driven nano locomotion

Hoshino Takayuki, Hori Yuichi, Konno Tomohiro, Ishihara Kazuhiko, Morishima Keisuke

p. 230-232　2008/01/01

Dual function surface prepared on polymeric substrate for highly sensitve immunoassay-based microarray biosensors

Sibarani James, Takai Madoka, Ishihara Kazuhiko

p. 248-250　2008/01/01

Long-term storage of living cells on chip for cell-based assays

Xu Yan, Konno Tomohiro, Sato Kae, Ishihara Kazuhiko, Kitamori Takehiko

p. 1852-1854　2008/01/01

Efficient immobilization methods of antibody on quartz crystal microbalance immunosensors

Kurosawa Shigeru, Aizawa Hidenobu, Park Jong Won, Ishihara Kazuhiko

Proceedings of the IEEE International Frequency Control Symposium and Exposition　p. 535-537　2007/12/01　Research paper (international conference proceedings)

Instantaneous determination via bimolecular recognition

Watanabe Junji, Ishihara Kazuhiko

Bioconjugate Chemistry　Vol. 18　No. 6　p. 1811-1817　2007/11/01　Research paper (scientific journal)

Photochemical oxidation of poly(dimethylsiloxane) surface and subsequent coating with biomimetic phosphorylcholine polymer

Hamada Yoshiteru, Ono Takao, Akagi Takanori, Ishihara Kazuhiko, Ichiki Takanori

Journal of Photopolymer Science and Technology　Vol. 20　No. 2　p. 245-249　2007/09/19　Research paper (scientific journal)

Preparations of aromatic diamine monomers and copolyamides containing phosphorylcholine moiety and the biocompatibility of copolyamides

Nagase Yu, Oku Masataka, Iwasaki Yasuhiko, Ishihara Kazuhiko

Polymer Journal　Vol. 39　No. 7　p. 712-721　2007/09/06　Research paper (scientific journal)

Effects of photo-induced graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on physical properties of cross-linked polyethylene in artificial hip joints

Kyomoto Masayuki, Moro Toru, Konno Tomohiro, Takadama Hiroaki, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Yamawaki Noboru, Ishihara Kazuhiko

Journal of Materials Science: Materials in Medicine　Vol. 18　No. 9　p. 1809-1815　2007/09/01　Research paper (scientific journal)

POLY 586-Cytocompatible phospholipid polymer hydrogel scaffold with bioconjugation of cell adhesive peptide sequence

Ishihara Kazuhiko, Maeta Eri, Takai Madoka, Konno Tomohiro

Abstracts of Papers of the American Chemical Society　Vol. 234　2007/08/19

POLY 584-Cell encapsulation hydrogel matrix "cell-container" prepared by spontaneous reversible gelation between water-soluble phospholipid polymer bearing phenylboronic acid moiety and polyols

Konno Tomohiro, Ishihara Kazuhiko

Abstracts of Papers of the American Chemical Society　Vol. 234　2007/08/19

Enhanced wear resistance of modified cross-linked polyethylene by grafting with poly(2-methacryloyloxyethyl phosphorylcholine)

Kyomoto Masayuki, Moro Toru, Konno Tomohiro, Takadama Hiroaki, Yamawaki Noboru, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 82　No. 1　p. 10-17　2007/07/01　Research paper (scientific journal)

High lubricious surface of cobalt-chromium-molybdenum alloy prepared by grafting poly(2-methacryloyloxyethyl phosphorylcholine)

Kyomoto Masayuki, Iwasaki Yasuhiko, Moro Toru, Konno Tomohiro, Miyaji Fumiaki, Kawaguchi Hiroshi, Takatori Yoshio, Nakamura Kozo, Ishihara Kazuhiko

Biomaterials　Vol. 28　No. 20　p. 3121-3130　2007/07/01　Research paper (scientific journal)

Friction behavior of high-density poly(2-methacryloyloxyethyl phosphorylcholine) brush in aqueous media

Kobayashi Motoyasu, Terayama Yuki, Hosaka Nao, Kaido Masataka, Suzuki Atsushi, Yamada Norifumi, Torikai Naoya, Ishihara Kazuhiko, Takahara Atsushi

Soft Matter　Vol. 3　No. 6　p. 740-746　2007/05/28　Research paper (scientific journal)

Efficacy of an MPC-BMA co-polymer as a nanotransporter for paclitaxel.

Masahiro Wada, Hiromitsu Jinno, Masakazu Ueda, Tadashi Ikeda, Masaki Kitajima, Tomohiro Konno, Junji Watanabe, Kazuhiko Ishihara

Anticancer research　Vol. 27　No. 3B　p. 1431-1436　2007/05/01　Research paper (scientific journal)

Multiple protein-immobilized phospholipid polymer nanoparticles

Watanabe Junji, Ishihara Kazuhiko

Nanobiotechnology　Vol. 3　No. 2　p. 76-82　2007/05/01　Research paper (scientific journal)

Tissue-compatible and adhesive polyion complex hydrogels composed of amphiphilic phospholipid polymers

Kimura Mizuna, Takai Madoka, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 18　No. 5　p. 623-640　2007/05/01　Research paper (scientific journal)

Efficacy of an MPC-BMA co-polymer as a nanotransporter for paclitaxel

Wada Masahiro, Jinno Hiromitsu, Ueda Masakazu, Ikeda Tadashi, Kitajima Masaki, Konno Tomohiro, Watanabe Junji, Ishihara Kazuhiko

Anticancer Research　Vol. 27　No. 3 B　p. 1431-1435　2007/05/01　Research paper (scientific journal)

Phosphorylcholine group-immobilized surface prepared on polydimethylsiloxane membrane by in situ reaction for its reduced biofouling

Ishihara Kazuhiko, Ando Bunya, Takai Madoka

Nanobiotechnology　Vol. 3　No. 2　p. 83-88　2007/05/01　Research paper (scientific journal)

Feasibility of a tiny centrifugal blood pump (TinyPump) for pediatric extracorporeal circulatory support

Ohuchi Katsuhiro, Hoshi Hideo, Iwasaki Yasuhiko, Ishihara Kazuhiko, Yoshikawa Masaharu, Ugaki Shinya, Ishino Kozo, Osaki Satoru, Kotani Yasuhiro, Sano Shunji, Takatani Setsuo

Artificial Organs　Vol. 31　No. 5　p. 408-412　2007/05/01　Research paper (scientific journal)

Nanoneedle surface modification with 2-methacryloyloxyethyl phosphorylcholine polymer to reduce nonspecific protein adsorption in a living cell

Kihara Takanori, Yoshida Narutoshi, Mieda Shingo, Fukazawa Kyoko, Nakamura Chikashi, Ishihara Kazuhiko, Miyake Jun

Nanobiotechnology　Vol. 3　No. 2　p. 127-134　2007/05/01　Research paper (scientific journal)

Surface modification by grafting with biocompatible 2-methacryloyloxyethyl phosphorylcholine for microfluidic devices

Sibarani James, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Key Engineering Materials　Vol. 342-343　p. 789-792　2007/04/16　Research paper (international conference proceedings)

Well defined surface preparation with phospholipid polymers for highly sensitive immunoassays

Poilane Nadia, Takai Madoka, Ishihara Kazuhiko

Key Engineering Materials　Vol. 342-343　p. 889-892　2007/04/16　Research paper (international conference proceedings)

Adhesion to cells of enzyme conjugated phospholipid polymer nanoparticles

Ito Tomomi, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Key Engineering Materials　Vol. 342-343　p. 785-788　2007/04/16　Research paper (international conference proceedings)

Prevention of tissue adhesion by a spontaneously formed phospholipid polymer hydrogel

Kimura Mizuna, Konno Tomohiro, Takai Madoka, Ishiyama Noriyuki, Moro Toru, Ishihara Kazuhiko

Key Engineering Materials　Vol. 342-343　p. 777-780　2007/04/16　Research paper (international conference proceedings)

Coating of anionic phospholipid polymer onto silica-based microchannel to minimize nonspecific protein adsorption

Xu Yan, Takai Madoka, Konno Tomohiro, Ishihara Kazuhiko

Key Engineering Materials　Vol. 342-343　p. 797-800　2007/04/16　Research paper (international conference proceedings)

Phospholipid polymer hydrogel formed by the photodimerization of cinnamoyl groups in the polymer side chain

Jun Yamaguchi, Junji Watanabe, Madoka Takai, Kazuhiko Ishihara

Journal of Applied Polymer Science　Vol. 104　No. 1　p. 44-50　2007/04/05　Research paper (scientific journal)

Phospholipid polymer hydrogel formed by the photodimerization of cinnamoyl groups in the polymer side chain

Yamaguchi Jun, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

Journal of Applied Polymer Science　Vol. 104　No. 1　p. 44-50　2007/04/05　Research paper (scientific journal)

Antibody immobilization to phospholipid polymer layer on gold substrate of quartz crystal microbalance immunosensor

Park Jongwon, Kurosawa Shigeru, Takai Madoka, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 55　No. 2　p. 164-172　2007/04/01　Research paper (scientific journal)

Temporal and spatially controllable cell encapsulation using a water-soluble phospholipid polymer with phenylboronic acid moiety

Konno Tomohiro, Ishihara Kazuhiko

Biomaterials　Vol. 28　No. 10　p. 1770-1777　2007/04/01　Research paper (scientific journal)

Erratum

Xu Yan, Takai Madoka, Konno Tomohiro, Ishihara Kazuhiko

Lab on a Chip - Miniaturisation for Chemistry and Biology　Vol. 7　No. 3　2007/03/08

Preparation of molecular dispersed polymer blend composed of polyethylene and poly(vinyl acetate) by in situ polymerization of vinyl acetate using supercritical carbon dioxide

Hoshi Toru, Sawaguchi Takashi, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Polymer　Vol. 48　No. 6　p. 1573-1580　2007/03/08　Research paper (scientific journal)

Nanometer-scale patterned surfaces for control of cell adhesion

Goto Makiko, Tsukahara Takehiko, Sato Kae, Konno Tomohiro, Ishihara Kazuhiko, Sato Kiichi, Kitamori Takehiko

Analytical Sciences　Vol. 23　No. 3　p. 245-247　2007/03/01　Research paper (scientific journal)

Novel immunosuppressant agents targeting activated lymphocytes by biocompatible MPC polymer conjugated with interleukin-2

Chiba N, Ueda M, Shimada T, Jinno H, Watanabe J, Ishihara K, Kitajima M

European Surgical Research　Vol. 39　No. 2　p. 103-110　2007/03/01　Research paper (scientific journal)

Cytocompatible biointerface on poly(lactic acid) by enrichment with phosphorylcholine groups for cell engineering

Watanabe Junji, Nederberg Fredrik, Atthoff Björn, Bowden Tim, Hilborn Jöns, Ishihara Kazuhiko

Materials Science and Engineering C　Vol. 27　No. 2　p. 227-231　2007/03/01　Research paper (scientific journal)

Development of gene vectors for pinpoint targeting to human hepatocytes by cationically modified polymer complexes

Chiba Naokazu, Ueda Masakazu, Shimada Toshiyuki, Jinno Hiromitsu, Watanabe Junji, Ishihara Kazuhiko, Kitajima Masaki

European Surgical Research　Vol. 39　No. 1　p. 23-34　2007/03/01　Research paper (scientific journal)

Microfluidic flow control on charged phospholipid polymer interface

Xu Yan, Takai Madoka, Konno Tomohiro, Ishihara Kazuhiko

Lab on a Chip - Miniaturisation for Chemistry and Biology　Vol. 7　No. 2　p. 199-206　2007/02/16　Research paper (scientific journal)

Photoinduced phospholipid polymer grafting on Parylene film

Goda Tatsuro, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 54　No. 1　p. 67-73　2007/01/15

Surface modification on microfluidic devices with 2-methacryloyloxyethyl phosphorylcholine polymers for reducing unfavorable protein adsorption

Sibarani James, Takai Madoka, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 54　No. 1　p. 88-93　2007/01/15　Research paper (scientific journal)

1P321 Surface modification of nanoneedle with MPC polymers for improving the biocompatibility with cell interior(Bioengineering,Poster Presentations)

Kihara Takanori, Yoshida Narutoshi, Nakamura Chikashi, Fukazawa Kyoko, Ishihara Kazuhiko, Miyake Jun

Seibutsu Butsuri　Vol. 47　No. 0　2007

Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels

Mizuna Kimura, Madoka Takai, Kazuhiko Ishihara

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A　Vol. 80A　No. 1　p. 45-54　2007/01　Research paper (scientific journal)

ホスホリルコリン基含有芳香族ポリアミドの合成と生体適合性

下山田直矢, 奥 正敬, 長瀬 裕, 岩崎泰彦, 石原一彦

東海大学紀要工学部　Vol. 46　No. 2　p. 5-10　2007

Preparation of Biointerface on Nanoparticle Surface by Atom Transfer Radical Polymerization

Ryosuke Matsuno, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 32　No. 2　p. 555-558　2007

Surface Nanopatterning of Phosphorylcholine Unit by Well-defined Block Copolymer Containing 2-Methacryloyloxyethyl Phosphorylcholine

Ji Hun Seo, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn　Vol. 32　No. 2　p. 567-570　2007

Nanoscale Surface Grafting with Phospholipid Polymer to Lubricate Polypropylene Surface

Kazuhiko Kitano, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Trans. Mater. Res. Soc. Jpn,　Vol. 32　No. 2　p. 579-582　2007

Preparation of biointerfaces using molecularly dispersed polymer alloys

Hoshi Toru, Sawaguchi Takashi, Matsuno Ryosuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

TRANSACTIONS OF THE MATERIALS RESEARCH SOCIETY OF JAPAN, VOL 32, NO 4　Vol. 32　No. 4　p. 1235-1238　2007　Research paper (international conference proceedings)

Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels

Kimura Mizuna, Takai Madoka, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 80　No. 1　p. 45-54　2007/01/01　Research paper (scientific journal)

Stress response of adherent cells on a polymer blend surface composed of a segmented polyurethane and MPC copolymers

Shin-Ichi Sawada, Yasuhiko Iwasaki, Nobuo Nakabayashi, Kazuhiko Ishihara

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A　Vol. 79A　No. 3　p. 476-484　2006/12　Research paper (scientific journal)

Precise control of phospholipids polymer on DNA separation chip with nanochannel

Takai Madoka, Shimizu Kyousuke, Ishihara Kazuhiko

p. 5000-5001　2006/12/01

Efficient production of MHC and TCR using water soluble polymer

Oshima Takashi, Suzuki Youzou, Tanaka Naoki, Kunugi Shigeru, Sakaki Shujiro, Ishihara Kazuhiko

2006/12/01

Preparation of biofunctional surface using nano hybrid of polyethylene / poly(vinyl acetate)

Hoshi Toru, Sawaguchi Takashi, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

p. 5118-5119　2006/12/01

Stress response of adherent cells on a polymer blend surface composed of a segmented polyurethane and MPC copolymers

Sawada Shin Ichi, Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 79　No. 3　p. 476-484　2006/12/01　Research paper (scientific journal)

Synthesis and functionality of poly(urethane-urea) containing phosphorylcholine moiety

Nagase Yu, Nakajima Satoru, Shimoyamada Naoya, Iwasaki Yasuhiko, Ishihara Kazuhiko

p. 3355-3356　2006/12/01

Well defined surface preparation with phospholipid polymers for highly sensitive immunoassays

Poilane Nadia, Takai Madoka, Ishihara Kazuhiko

p. 5065-5066　2006/12/01

Recoverable phospholipid polymer hydrogels based on covalently complex as cell-container

Konno Tomohiro, Ishihara Kazuhiko

p. 5266-5267　2006/12/01

2006 Frank Stinchfield award

Moro Toru, Takatori Yoshio, Ishihara Kazuhiko, Nakamura Kozo, Kawaguchi Hiroshi

Clinical Orthopaedics and Related Research　No. 453　p. 58-63　2006/12/01　Research paper (scientific journal)

Development of high density immobilized biomolecule surface for high sensitivity clinical diagnosis device

Nishizawa Kazuki, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

p. 5519-5520　2006/12/01

Enzymatic photochemical sensing using luciferase-immobilized polymer nanoparticles covered with artificial cell membrane

Konno Tomohiro, Ito Tomomi, Takai Madoka, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 17　No. 12　p. 1347-1357　2006/12/01　Research paper (scientific journal)

Synthesis and biocompatibility of polyamides containing phosphorylcholine moiety

Shimoyamada Naoya, Yogo Azusa, Horiguchi Kenji, Nagase Yu, Akiyama Eiichi, Iwasaki Yasuhiko, Ishihara Kazuhiko

2006/12/01

Antiwearable and biocompatible surface of artificial HIP joints by nano-scaled grafting with phsopholipid polymers

Ishihara Kazuhiko, Moro Toru, Takatori Yoshio, Kawaguchi Hiroshi, Nakamura Kozo, Konno Tomohiro

2006/12/01

Preparation of MPC-introduced polyrotaxanes and their solution properties

Akita Kunihiko, Katoono Ryo, Yui Nobuhiko, Ooya Tooru, Konno Tomohiro, Ishihara Kazuhiko

p. 5340-5341　2006/12/01

Investigation into mechanism of protein resistance based on hydration states in polymer chains

Morisaku Toshinori, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

p. 5416-5417　2006/12/01

Anti-tissue-adhesive hydrogel prepared from water-soluble phospholipid polymers

Kimura Mizuna, Ishiyama Noriyuki, Moro Toru, Takai Madoka, Ishihara Kazuhiko

p. 5499-5500　2006/12/01

Interaction between phospholipids and biocompatible polymers containing a phosphorylcholine moiety<sup/>

Kojima Masayoshi, Ishihara Kazuhiko, Watanabe Akihiko, Nakabayashi Nobuo

The Biomaterials: Silver Jubilee Compendium　p. 69-72　2006/12/01　Part of collection (book)

Frictional properties of hydrophilic polymer brushes under wet condition

Kobayashi Motoyasu, Matsuda Yasuhiro, Wang Zhe, Takahara Atsushi, Torikai Naoya, Kaido Masataka, Suzuki Atsushi, Ishihara Kazuhiko

p. 4336-4337　2006/12/01

Advanced nanobiomedical application of the phosphorylcholine-polymer surface technology (PCST)

Ishihara Kazuhiko, Takai Madoka, Watanabe Junji

2006/12/01

Aldosterone synthesis and cytokine production in human peripheral blood mononuclear cells

Miura Ryuzea, Nakamura Kazufumi, Miura Daiji, Miura Aya, Hisamatsu Kenichi, Kajiya Masahito, Hashimoto Katsushi, Nagase Satoshi, Morita Hiroshi, Kusano Kengo Fukushima, Emori Tetsuro, Ishihara Kazuhiko, Ohe Tohru

Journal of Pharmacological Sciences　Vol. 102　No. 3　p. 288-295　2006/11/27　Research paper (scientific journal)

Dimension of poly(2-methacryloyloxyethyl phosphorylcholine) in aqueous solutions with various ionic strength

Matsuda Yasuhiro, Kobayashi Motoyasu, Annaka Masahiko, Ishihara Kazuhiko, Takahara Atsushi

Chemistry Letters　Vol. 35　No. 11　p. 1310-1311　2006/11/05　Research paper (scientific journal)

High sensitivity ELISA chip using phospholipid polymer interface

Nishizawa Kazuki, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Analysis of cellular behavior of attachment and spreading by QCM combined with micro channel

Watarai Etsuko, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

MPC polymerization on surface of metal and evaluation of gradual drug releasing

Horie Taisuke, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Surface characterization of antibiofouling silicone elastomer by hydrophilication

Goda Tatsuro, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Novel procedure to modify hydrogels with phosphrilcholine compounds, "A biocompatible contact lens to prevent non-specific protein adsorption"

Suda Yukimitsu, Maeno Katsuyuki, Miyazawa Kazuyuki, Ishihara Kazuhiko

2006/10/19

Phospholipid polymerhydrogel using the photocrosslinking to fabricate the enzyme immobilizing membrane

Yamaguchi Jim, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Efficient production of T-cell receptor protein using chaperone-like polymer

Oshima Takashi, Ishihara Kazuhiko, Kunugi Shigeru, Tanaka Naoki

2006/10/19

Preparation of cyto-compatible phospholipid polymer matrix formed by self-closslinkage

Konno Tomohiro, Ishihara Kazuhiko

2006/10/19

Controlling bio-reaction on the interface of the nanoparticles by pH response polymer chain

Ito Tomomi, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Biomembrane mimetic anti-bioadsorption interface constructed for microfluidic devices

Xu Yan, Takai Madoka, Konno Tomohiro, Ishihara Kazuhiko

2006/10/19

Preparation of hybrid-type vascular prosthesis using phospholipid polymer surfaces with cell substitution function

Makita Kayahiko, Miura Ryuzea, Ye Sang Mo, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Preparation of biomolecules recognizable artificial cell membrane surface by a novel molecular imprinting method

Fukazawa Kyoko, Ishihara Kazuhiko

Polymer Preprints, Japan　Vol. 55　No. 1　2006/10/19　Research paper (international conference proceedings)

Producing the poly (MPC) gel containing phosphate group

Ohno Yohei, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Effect of surface grafted hydrophilic polymer chains to reduce the friction character

Kitano Kazuhiko, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Preparation of polyolefin materials with biocompatible surface using supercritical carbon dioxide fluid

Hoshi Toru, Sawaguchi Takashi, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2006/10/19

Effect of grafting density of poly(2-methacryloyloxyethyl phosphorylcholine) brush on the tribological properties

Kobayashi Motoyasu, Zhe Wang, Ishihara Kazuhiko, Takahara Atsushi

2006/10/18

Quartz crystal microbalance immunosensors for environmental monitoring

Kurosawa Shigeru, Park Jong Won, Aizawa Hidenobu, Wakida Shin Ichi, Tao Hiroaki, Ishihara Kazuhiko

Biosensors and Bioelectronics　Vol. 22　No. 4 SPEC. ISS.　p. 473-481　2006/10/15　Research paper (scientific journal)

Biomimetic phosphorylcholine polymer grafting from polydimethylsiloxane surface using photo-induced polymerization

Goda Tatsuro, Konno Tomohiro, Takai Madoka, Moro Toru, Ishihara Kazuhiko

Biomaterials　Vol. 27　No. 30　p. 5151-5160　2006/10/01　Research paper (scientific journal)

POLY 429-Recoverable polymer hydrogels based on covalently complex by new cytocompatible phospholipid polymers

Konno Tomohiro, Ishihara Kazuhiko

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY　Vol. 232　2006/09/10

PMSE 78-Poly(p-phenylene sulfonic acid) graft copolymers: Washing, temperature and relative humidity, effect on conductivity

Konno Tomohiro, Ishihara Kazuhiko

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY　Vol. 232　p. 227-227　2006/09/10

Anti-inflammatory effect of spironolactone on human peripheral blood mononuclear cells

Miura Ryuzea, Nakamura Kazufumi, Miura Daiji, Miura Aya, Hisamatsu Kenichi, Kajiya Masahito, Nagase Satoshi, Morita Hiroshi, Kengo Fukushima Kusano, Ohe Tohru, Ishihara Kazuhiko

Journal of Pharmacological Sciences　Vol. 101　No. 3　p. 256-259　2006/07/31　Research paper (scientific journal)

Biocompatible and biodegradable phosphorylcholine ionomers with reduced protein adsorption and cell adhesion

Nederberg Fredrik, Watanabe Junji, Ishihara Kazuhiko, Hilborn Jöns, Bowden Tim

Journal of Biomaterials Science, Polymer Edition　Vol. 17　No. 6　p. 605-614　2006/06/01　Research paper (scientific journal)

Dual mode bioreactions on polymer nanoparticles covered with phosphorylcholine group

Ito Tomomi, Watanabe Junji, Takai Madoka, Konno Tomohiro, Iwasaki Yasuhiko, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 50　No. 1　p. 55-60　2006/06/01　Research paper (scientific journal)

Asymmetrically functional surface properties on biocompatible phospholipid polymer membrane for bioartificial kidney

Hideto Ueda, Junji Watanabe, Tomohiro Konno, Madoka Takai, Akira Saito, Kazuhiko Ishihara

Journal of Biomedical Materials Research Part A　Vol. 77A　No. 1　p. 19-27　2006/04/01　Research paper (scientific journal)

Asymmetrically functional surface properties on biocompatible phospholipid polymer membrane for bioartificial kidney.

Ueda H, Watanabe J, Konno T, Takai M, Saito A, Ishihara K

Journal of biomedical materials research. Part A　Vol. 77　No. 1　p. 19-27　2006/04　Research paper (scientific journal)

Asymmetrically functional surface properties on biocompatible phospholipid polymer membrane for bioartificial kidney

Ueda Hideto, Watanabe Junji, Konno Tomohiro, Takai Madoka, Saito Akira, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 77　No. 1　p. 19-27　2006/04/01　Research paper (scientific journal)

High functional hollow fiber membrane modified with phospholipid polymers for a liver assist bioreactor

Ye Sang Ho, Watanabe Junji, Takai Madoka, Iwasaki Yasuhiko, Ishihara Kazuhiko

Biomaterials　Vol. 27　No. 9　p. 1955-1962　2006/03/01　Research paper (scientific journal)

Soft contact lens biomaterials from bioinspired phospholipid polymers

Goda Tatsuro, Ishihara Kazuhiko

Expert Review of Medical Devices　Vol. 3　No. 2　p. 167-174　2006/03/01

Water structure and improved mechanical properties of phospholipid polymer hydrogel with phosphorylcholine centered intermolecular cross-linker

Goda Tatsuro, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

Polymer　Vol. 47　No. 4　p. 1390-1396　2006/02/08　Research paper (scientific journal)

Biofouling Control by Phospholipid Polymer on Microchannnel DNA Separation

Kyousuke Shimizu, Yu Nagase, Madoka Takai, Kazuhiko Ishihara

Transactions of the Material Research Society of Japan,　Vol. 31　No. 4　p. 1069-1072　2006

Constructing biomembrane-mimic interface for cell separation in microfluidic chip

Yan Xu, Madoka Takai, Kazuhiko Ishihara

Transactions of Materials Research Society of Japan　Vol. 31　No. 3　p. 645-648　2006　Research paper (scientific journal)

Electrosprayed phospholipid polymer surface for enhanced sensitive ELISA chip

Nishizawa Kazuki, Takai Madoka, Ishihara Kazuhiko

p. 335-337　2006/01/01

Sequential enzymatic reactions and stability of biomolecules immobilized onto phospholipid polymer nanoparticles

Watanabe Junji, Ishihara Kazuhiko

Biomacromolecules　Vol. 7　No. 1　p. 171-175　2006/01/01　Research paper (scientific journal)

DNA separation on nanochannel with phospholipid polymers

Takai Madoka, Shimizu Kyousuke, Nagase Yu, Ishihara Kazuhiko

p. 885-887　2006/01/01

Protein antiadsorption modification by negatively charged phospholipid polymer for microsystem needing electroosmotic flow

Xu Yan, Takai Madoka, Konno Tomohiro, Ishihara Kazuhiko

p. 215-217　2006/01/01

Micro/nano-patterned surfaces for control of cell adhesion and cell functions

Goto Makiko, Sato Kae, Tsukahara Takehiko, Konno Tomohiro, Ishihara Kazuhiko, Kitamori Takehiko

p. 993-995　2006/01/01

Piezoelectric immunosensor for bisphenol A based on signal enhancing step with 2-methacrolyloxyethyl phosphorylcholine polymeric nanoparticle

Park Jong Won, Kurosawa Shigeru, Aizawa Hidenobu, Goda Yasuhiro, Takai Madoka, Ishihara Kazuhiko

Analyst　Vol. 131　No. 1　p. 155-162　2006/01/01　Research paper (scientific journal)

Non-biofouling surface for microchannel device by grafting with biocompatible 2-methacryloyloxyethyl phosphorylcholine for obtaining high S/N ratio

Sibarani James, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

p. 212-214　2006/01/01

Synthesis of sequence-controlled copolymers from extremely polar and apolar monomers by living radical polymerization and their phase-separated structures

Yuuki Inoue, Junji Watanabe, Madoka Takai, Shin-ichi Yusa, Kazuhiko Ishihara

Journal of Polymer Science Part A: Polymer Chemistry　Vol. 43　No. 23　p. 6073-6083　2005/12/01　Research paper (scientific journal)

Thermo-responsive and biocompatible block copolymers

Fukuda Kenichi, Yusa Shin Ichi, Yamamoto Tohei, Ishihara Kazuhiko, Morishima Yotaro

2005/12/01

Synthesis and property of aromatic polyamides containing phosphorylcholine moiety

Shimoyamada Naoya, Oku Masataka, Nakajima Satoru, Nagase Yu, Iwasaki Yasuhiko, Ishihara Kazuhiko

2005/12/01

Non-adsorption surface construction in DNA separation chip

Shimizu Kyousuke, Nagase Yu, Takai Madoka, Ishihara Kazuhiko

p. 5141-5142　2005/12/01

Fabrication of tissue compatible phospholipid polymer matrix for 3D cell culture

Maeta Eri, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

p. 5233-5234　2005/12/01

Surface grafting of biocompatible 2-methacryloyloxyethyl phosphorylcholine (MPC) onto conventional biomaterials for protein prevention in microchip

Sibarani James, Takai Madoka, Ishihara Kazuhiko

p. 5229-5230　2005/12/01

Synthesis of aromatic carboxylic acid compound containing phosphorylcholine moiety and the application to polymer reaction

Tadokoro Yoshinori, Oku Masataka, Nagase Yu, Iwasaki Yasuhiko, Ishihara Kazuhiko

Vol. 31　No. 4　2005/12/01

Design of a double functional interface polymer with artificial biomembrane for control of anti-and pro-tissue adhesion

Kimura Mizuna, Konno Tomohiro, Moro Toru, Takai Madoka, Ishihara Kazuhiko

p. 5231-5232　2005/12/01

Synthesis and characterization on polydimethylsiloxane grafted with poly(2-methacryloyloxyethyl phosphorylcholine) by photo-induced radical polymerization

Goda Tatsuro, Konno Tomohiro, Takai Madoka, Ishihara Kazuhiko

2005/12/01

Fabrication of Histocompatible Phospholipid polymer matrix for 3D cell culture

Maeta Eri, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

2005/12/01

Synthesis and property of poly(urethane-urea) containing phosphorylcholine moiety

Nakajima Satoru, Oku Masataka, Nagase Yu, Iwasaki Yasuhiko, Ishihara Kazuhiko

2005/12/01

Synthesis and biocompatibility of poly (urethane-urea) containing phosphorylcholine moiety

Nakajima Satoru, Shimoyamada Naoya, Katumata Kenichi, Nagase Yu, Iwasaki Yasuhiko, Ishihara Kazuhiko

p. 4951-4952　2005/12/01

Photocrosslinkable and biocompatible phospholipid polymer for making hydrogel in microfluidic devices

Yamaguchi Jun, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

Transactions of the Materials Research Society of Japan, Vol 30, No 4　Vol. 30　No. 4　p. 1081-1084　2005/12/01　Research paper (international conference proceedings)

High sensitivity ELISA using phospholipid polymer interface

Nishizawa Kazuki, Takai Madoka, Ishihara Kazuhiko

p. 5139-5140　2005/12/01

Spontaneously forming hydrogel from water-soluble random- and block-type phospholipid polymers

Kimura Mizuna, Fukumoto Kikuko, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

Biomaterials　Vol. 26　No. 34　p. 6853-6862　2005/12/01　Research paper (scientific journal)

Producing laminated-type glucose sensor with polymer mediator for blood analysis

Himuro Yoko, Takai Madoka, Ishihara Kazuhiko

2005/12/01

Design of bioconjugate phospholipid polymers with sustainable biological activities

Watanabe Junji, Ishihara Kazuhiko

2005/12/01

TiO₂ nanoparticles with artifictial bio-membarane for bio-separation

Matsui Kenji, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

2005/12/01

Behavior of MPC/HEMA copolymers in solutions

Miyashita Naoki, Shindo Yoichi, Fukumoto Kikuko, Ishihara Kazuhiko

2005/12/01

Tribological properties of hydrophilic polymer brushes

Kobayashi Motoyasu, Takahara Atsushi, Ishihara Kazuhiko

p. 3814-3815　2005/12/01

Hybrid artificial blood vessel with J-curve properties by segmented polyurethane unsymmetrical hollow fiber

Makita Kayahiko, Hoye Sang, Watanabe Junji, Tarai Madoka, Ishihara Kazuhiko

2005/12/01

Functional conversion of enzyme by MPC/BMA/IPMS copolymers

Takenaka Yosuke, Hukumoto Kikuko, Shindo Yoichi, Ishihara Kazuhiko

2005/12/01

Synthesis of sequence-controlled copolymers from extremely polar and apolar monomers by living radical polymerization and their phase-separated structures

Inoue Yuuki, Watanabe Junji, Takai Madoka, Yusa Shin Ichi, Ishihara Kazuhiko

Journal of Polymer Science, Part A: Polymer Chemistry　Vol. 43　No. 23　p. 6073-6083　2005/12/01

Importance of water structure on molecular design of biocompatible hydrogel

Morisaku Toshinori, Ikehara Takayuki, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

2005/12/01

Interface construction of high sensitivity biochip modified with phospholipids polymers

Takai Madoka, Ishihara Kazuhiko

p. 5131-5132　2005/12/01

High sensitive bio-marker detection by fluorescence resonance energy transfer onto phospholipid polymer nanoparticles

Watanabe Junji, Ishihara Kazuhiko

p. 3036-3037　2005/12/01

Bioadhesive polyion complex composed of water-soluble phospholipid polymers

Kimura Mizuna, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

2005/12/01

Phospholipid polymer grafted of isotactic oligo lactic acid for tissue engineering material

Takami Kimiaki, Watanabe Jyunji, Takai Madoka, Ishihara Kazuhiko

2005/12/01

Behavior of MPC/HEMA copolymers in aqueous solutions

Miyashita Naoki, Fukumotq Kikuko, Shindo Yoichi, Ishihara Kazuhiko

2005/12/01

Facilitated disassembly of polyplexes composed of self-assembling amphiphilic polycations enhances the gene transfer efficacy

Kitagawa Tatsuya, Iwase Reiko, Ishihara Kazuhiko, Yamaoka Tetsuji, Murakami Akira

Chemistry Letters　Vol. 34　No. 11　p. 1478-1479　2005/11/05　Research paper (scientific journal)

Organo hydrogel hybrids. Formation of reservoirs for protein delivery

Nederberg Fredrik, Watanabe Junji, Ishihara Kazuhiko, Hilborn Jöns, Bowden Tim

Biomacromolecules　Vol. 6　No. 6　p. 3088-3094　2005/11/01　Research paper (scientific journal)

Molecularly engineered p(HEMA)-based hydrogels for implant biochip biocompatibility

Abraham Sheena, Brahim Sean, Ishihara Kazuhiko, Guiseppi-Elie Anthony

Biomaterials　Vol. 26　No. 23　p. 4767-4778　2005/08/01　Research paper (scientific journal)

Design of functional hollow fiber membranes modified with phospholipid polymers for application in total hemopurification system

Ye Sang Ho, Watanabe Junji, Takai Madoka, Iwasaki Yasuhiko, Ishihara Kazuhiko

Biomaterials　Vol. 26　No. 24　p. 5032-5041　2005/08/01　Research paper (scientific journal)

Adsorption of fibrinogen and lysozyme on silicon grafted with poly(2-methacryloyloxyethyl phosphorylcholine) via surface-initiated atom transfer radical polymerization

Feng Wei, Zhu Shiping, Ishihara Kazuhiko, Brash John L

Langmuir　Vol. 21　No. 13　p. 5980-5987　2005/06/21　Research paper (scientific journal)

Network structure of spontaneously forming physically cross-link hydrogel composed of two-water soluble phospholipid polymers

Nam Kwangwoo, Watanabe Junji, Ishihara Kazuhiko

Polymer　Vol. 46　No. 13　p. 4704-4713　2005/06/17　Research paper (scientific journal)

Phospholipid polymer surfaces reduce bacteria and leukocyte adhesion under dynamic flow conditions

Patel Jasmine D, Iwasaki Yasuhiko, Ishihara Kazuhiko, Anderson James M

Journal of Biomedical Materials Research - Part A　Vol. 73　No. 3　p. 359-366　2005/06/01　Research paper (scientific journal)

Cell engineering biointerface focusing on cytocompatibility using phospholipid polymer with an isomeric oligo(lactic acid) segment

Watanabe Junji, Ishihara Kazuhiko

Biomacromolecules　Vol. 6　No. 3　p. 1797-1802　2005/05/01　Research paper (scientific journal)

Photo-immobilization of a phospholipid polymer for surface modification

Konno Tomohiro, Hasuda Hirokazu, Ishihara Kazuhiko, Ito Yoshihiro

Biomaterials　Vol. 26　No. 12　p. 1381-1388　2005/04/01　Research paper (scientific journal)

Cell separation in microcanal coated with electrically charged phospholipid polymers

Ito Tomomi, Iwasaki Yasuhiko, Narita Tadashi, Akiyoshi Kazunari, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 41　No. 2-3　p. 175-180　2005/03/15　Research paper (scientific journal)

Synthesis of well-defined amphiphilic block copolymers having phospholipid polymer sequences as a novel biocompatible polymer micelle reagent

Yusa Shin Ichi, Fukuda Kenichi, Yamamoto Tohei, Ishihara Kazuhiko, Morishima Yotaro

Biomacromolecules　Vol. 6　No. 2　p. 663-670　2005/03/01　Research paper (scientific journal)

In situ modification on cellulose acetate hollow fiber membrane modified with phospholipid polymer for biomedical application

Ye Sang Ho, Watanabe Junji, Iwasaki Yasuhiko, Ishihara Kazuhiko

Journal of Membrane Science　Vol. 249　No. 1-2　p. 133-141　2005/03/01　Research paper (scientific journal)

Molecular design of reactive amphiphilic phospholipid polymer for bioconjugation with an enzyme

Miyamoto Daisuke, Watanabe Junji, Ishihara Kazuhiko

Journal of Applied Polymer Science　Vol. 95　No. 3　p. 615-622　2005/02/05　Research paper (scientific journal)

Phosphorylcholine-containing polymers for biomedical applications

Iwasaki Yasuhiko, Ishihara Kazuhiko

Analytical and Bioanalytical Chemistry　Vol. 381　No. 3　p. 534-546　2005/02/01　Research paper (scientific journal)

Tissue compatible segmented polyurethane hollow fiber as a scaffold for hybrid blood vessel

Kayahiko Makita, Sang Ho Ye, Junji Watanabe, Madoka Takai, Kazuhiko Ishihara

Transactions of the Materials Research Society of Japan, Vol 30, No 4　Vol. 30　No. 4　p. 1077-1080　2005　Research paper (international conference proceedings)

Design of micro-biosensors in healthcare chip for convenient blood diagnostics

Madoka Takai, Hiroki Ogawa, Masao Nagai, Kazuhiko Ishihara, Yasuhiro Horiike

Transactions of the Materials Research Society of Japan, Vol 30, No 4　Vol. 30　No. 4　p. 1247-1250　2005　Research paper (international conference proceedings)

Preparation and biocompatibitity of aromatic polyamides containing phosphorylcholine moiety

Oku, M, Nakajima, S, Tadokoro, Y, Shimoyamada, N, Nagase, Y, Iwasaki, Y, Ishihara, K, Somiya, S, Doyama, M

Trans Mater Res Soc Jpn　Vol. 30　No. 4　2005

ホスホリルコリン基含有ポリ(ウレタン-ウレア)の合成と生体適合性

中島 智, 奥 正敬, 長瀬 裕, 岩崎 泰彦, 石原 一彦

東海大学紀要工学部　Vol. 44　No. 2　p. 1-8　2005

Protein adsorption resistance by biocompatible phospolipid polymers as a surface modification on PDMS

Ishihara Kazuhiko, Sibarani James, Takai Madoka

p. 253-255　2005/01/01

BioConjugate enzyme with phospholipid polymers for improvement of its stability

Miyamoto D, Watanabe J, Ishihara K

2004/12/01

Design of electrochemical biosensor in healthcare chip for multi-item blood analysis

Takai M, Shinbashi S, Himuro Y, Ogawa H, Horiike Y, Ishihara K

2004/12/01

Preparation of biointerface by finely designed phosphorylcholine polymers

Inoue Y, Watanabe J, Takai M, Ishihara K

2004/12/01

Fabrication of micropatterned surfaces within subcellular dimensions for spatial localization of cell adhesive proteins

Ando B, Watanabe J, Takai M, Ishihara K

2004/12/01

Novel block-type phospholipid polymers with spontaneous gelation properties for making in situ setting drug reservoir

Kimura M, Fukumoto K, Watanabe J, Takai M, Ishihara K

2004/12/01

Antithrombogenic polymer alloy containing phospholipid polymer

Ishihara K, Ogawa R, Hasegawa T, Nishiuchi D, Watanabe J, Iwasaki Y

2004/12/01

Cellulose acetate hollow fiber membranes modified by phospholipid polymers for hemopurification

Ye S. H, Watanabe J, Ishihara K

2004/12/01

A water-soluble phospholipid polymer as a new biocompatible synthetic DNA carrier

Sakaki Shujiro, Tsuchida Mamoru, Iwasaki Yasuhiko, Ishihara Kazuhiko

Bulletin of the Chemical Society of Japan　Vol. 77　No. 12　p. 2283-2288　2004/12/01　Research paper (scientific journal)

Bioartificial kidney with renal tubule epithelial cells on biocompatible porous membrane modified by phospholipid polymer

Ueda H, Watanabe J, Takai M, Ishihara K

2004/12/01

Cytocompatible scaffold using phospholipid polymer grafted with poly(D,L-lactic acid) segments

Watanabe J, Ishihara K

2004/12/01

Improved mechanical properties of phospholipid polymer hydrogels cross-linked with novel bifunctional monomer bearing phosphorylcholine unit

Goda T, Kiritoshi Y, Watanabe J, Takai M, Ishihara K

2004/12/01

Improved longevity of the artificial joints by grafting of biocompatible phospholipid polymer on the polyethylene liner

Moro T, Takatori Y, Ishihara K, Konno T, Takigawa Y, Nakamura K, Kawaguchi H

2004/12/01

Implantable polymeric artificial pancreas

Uchiyama Tomoaki, Watanabe Junji, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 15　No. 10　p. 1237-1262　2004/11/08

The characteristics of spontaneously forming physically cross-linked hydrogels composed of two water-soluble phospholipid polymers for oral drug delivery carrier I

Nam Kwangwoo, Watanabe Junji, Ishihara Kazuhiko

European Journal of Pharmaceutical Sciences　Vol. 23　No. 3　p. 261-270　2004/11/01　Research paper (scientific journal)

Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis

Moro Toru, Takatori Yoshio, Ishihara Kazuhiko, Konno Tomohiro, Takigawa Yorinobu, Matsushita Tomiharu, Chung Ung I L, Nakamura Kozo, Kawaguchi Hiroshi

Nature Materials　Vol. 3　No. 11　p. 829-836　2004/11/01　Research paper (scientific journal)

Surface characteristics of block-type copolymer composed of semi-fluorinated and phospholipid segments synthesized by living radical polymerization

Inoue Yuuki, Watanabe Junji, Takai Madoka, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 15　No. 9　p. 1153-1166　2004/10/15　Research paper (scientific journal)

Synthesis of hydrophilic cross-linker having phosphorylcholine-like linkage for improvement of hydrogel properties

Kiritoshi Yoshihiro, Ishihara Kazuhiko

Polymer　Vol. 45　No. 22　p. 7499-7504　2004/10/13　Research paper (scientific journal)

Highly Efficient Sequential Enzymatic Reaction on Bio-Conjugate Phospholipid Polymer Nanoparticles

KOBUNSHI RONBUNSHU　Vol. 61　No. 10　p. 547-554　2004/10/01　Research paper (scientific journal)

Highly efficient sequential enzymatic reaction on bio-conjugate phospholipid polymer nanoparticles

Watanabe Junji, Ishihara Kazuhiko

Kobunshi Ronbunshu　Vol. 61　No. 10　p. 547-554　2004/10/01　Research paper (scientific journal)

Nano-scale surface modification of a segmented polyurethane with a phospholipid polymer

Morimoto Nobuyuki, Watanabe Akihiko, Iwasaki Yasuhiko, Akiyoshi Kazunari, Ishihara Kazuhiko

Biomaterials　Vol. 25　No. 23　p. 5353-5361　2004/10/01　Research paper (scientific journal)

Development of a microglucose sensor for healthcare chip that allows multi-item measurements

Takai Madoka, Shinbashi Satomi, Ogawa Hiroki, Nagai Masao, Ishihara Kazuhiko, Horiike Yasuhiro

Kobunshi Ronbunshu　Vol. 61　No. 10　p. 555-560　2004/10/01　Research paper (scientific journal)

Cellulose acetate hollow fiber membranes blended with phospholipid polymer and their performance for hemopurification

Ye Sang Ho, Watanabe Junji, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 15　No. 8　p. 981-1001　2004/09/24　Research paper (scientific journal)

Surface characteristics of block-type copolymer composed of semi-fluorinated and phospholipid segments synthesized by living radical polymerization

Yuuki Inoue, Junji Watanabe, Madoka Takai, Kazuhiko Ishihara

Journal of Biomaterials Science, Polymer Edition　Vol. 15　No. 9　p. 1153-1166　2004/09/01　Research paper (scientific journal)

Properties of blend polymers composed of phospholipid polymer and photocrosslinkable PVA

Shindo Yoichi, Kozaki Masaya, Fukumoto Kikuko, Ishihara Kazuhiko

Journal of Photopolymer Science and Technology　Vol. 17　No. 1　p. 75-76　2004/07/22　Research paper (scientific journal)

Hydrogen-bonding-driven spontaneous gelation of water-soluble phospholipid polymers in aqueous medium

Kimura Mizuna, Fukumoto Kikuko, Watanabe Junji, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 15　No. 5　p. 631-644　2004/07/09　Research paper (scientific journal)

Dynamic motion of phosphorylcholine groups at the surface of poly(2-methacryloyloxyethyl phosphorylcholine-random-2,2,2-trifluoroethyl methacrylate)

Inoue Yuuki, Watanabe Junji, Ishihara Kazuhiko

Journal of Colloid and Interface Science　Vol. 274　No. 2　p. 465-471　2004/06/15　Research paper (scientific journal)

Modeling of swelling and drug release behavior of spontaneously forming hydrogels composed of phospholipid polymers

Nam Kwangwoo, Watanabe Junji, Ishihara Kazuhiko

International Journal of Pharmaceutics　Vol. 275　No. 1-2　p. 259-269　2004/05/04　Research paper (scientific journal)

Evaluation of 2-Methacryloyloxyethyl Phosphorylcholine Polymeric Nanoparticle for Immunoassay of C-Reactive Protein Detection

Park Jongwon, Kurosawa Shigeru, Watanabe Junji, Ishihara Kazuhiko

Analytical Chemistry　Vol. 76　No. 9　p. 2649-2655　2004/05/01　Research paper (scientific journal)

Regulation of enzyme-substrate complexation by a substrate conjugated with a phospholipid polymer

Takei Keigo, Konno Tomohiro, Watanabe Junji, Ishihara Kazuhiko

Biomacromolecules　Vol. 5　No. 3　p. 858-862　2004/05/01　Research paper (scientific journal)

Novel biodegradable polyphosphate cross-linker for making biocompatible hydrogel

Iwasaki Yasuhiko, Nakagawa Chigusa, Ohtomi Michiko, Ishihara Kazuhiko, Akiyoshi Kazunari

Biomacromolecules　Vol. 5　No. 3　p. 1110-1115　2004/05/01　Research paper (scientific journal)

Polyethylene/phospholipid polymer alloy as an alternative to poly(vinylchloride)-based materials

Ishihara Kazuhiko, Nishiuchi Daisuke, Watanabe Junji, Iwasaki Yasuhiko

Biomaterials　Vol. 25　No. 6　p. 1115-1122　2004/03/01　Research paper (scientific journal)

Conjugation of enzymes on polymer nanoparticles covered with phosphorylcholine groups

Konno T, Watanabe J, Ishihara K

Biomacromolecules　Vol. 5　No. 2　p. 342-347　2004/03/01　Research paper (scientific journal)

An enzyme-immobilization method for integration of biofunctions on a microchip using a water-soluble amphiphilic phospholipid polymer having a reacting group

Sakai-Kato Kumiko, Kato Masaru, Ishihara Kazuhiko, Toyo'oka Toshimasa

Lab on a Chip - Miniaturisation for Chemistry and Biology　Vol. 4　No. 1　p. 4-6　2004/02/01　Research paper (scientific journal)

Highly Stabilized Papain Conjugated with Water-Soluble Phospholipid Polymer Chain Having a Reacting Terminal Group

Miyamoto Daisuke, Watanabe Junji, Ishihara Kazuhiko

Journal of Applied Polymer Science　Vol. 91　No. 2　p. 827-832　2004/01/15　Research paper (scientific journal)

Polymer alloy composed polyethylene and phospholipids polymer as green biomaterials

Ishihara K, Nishiuchi D, Watanabe J, Iwasaki Y

Biomaterials　Vol. 25:1115-1122　2004

Effect of water-soluble phospholipid polymers conjugated with papain on the enzymatic stability

Miyamoto Daisuke, Watanabe Junji, Ishihara Kazuhiko

Biomaterials　Vol. 25　No. 1　p. 71-76　2004/01/01　Research paper (scientific journal)

Pico liter dispenser with 128 independent nozzles for high throughput biochip fabrication

Takagi F, Kurosawa R, Sawaki D, Kamisuki S, Takai M, Ishihara K, Atobe M

MEMS 2004: 17TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, TECHNICAL DIGEST　p. 276-279　2004　Research paper (international conference proceedings)

In vitro and ex vivo blood compatibility study of 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymer-coated hemodialysis hollow fibers

Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Artificial Organs　Vol. 6　No. 4　p. 260-266　2003/12/01　Research paper (scientific journal)

Degradation of phospholipid polymer hydrogel by hydrogen peroxide aiming at insulin release device

Uchiyama Tomoaki, Kiritoshi Yoshihiro, Watanabe Junji, Ishihara Kazuhiko

Biomaterials　Vol. 24　No. 28　p. 5183-5190　2003/12/01　Research paper (scientific journal)

Structure of Water in the Vicinity of Phospholipid Analogue Copolymers as Studied by Vibrational Spectroscopy

Kitano Hiromi, Imai Makoto, Mori Takayuki, Gemmei-Ide Makoto, Yokoyama Yoshiyuki, Ishihara Kazuhiko

Langmuir　Vol. 19　No. 24　p. 10260-10266　2003/11/25　Research paper (scientific journal)

Science and Technology of Advanced Materials

Ishihara K

Science and Technology of Advanced Materials　Vol. 4　No. 6　2003/11/01　Research paper (scientific journal)

Change in cell adhesion property on cytocompatible interface using phospholipid polymer grafted with poly(D,L-lactic acid) segment for tissue engineering

Watanabe Junji, Ishihara Kazuhiko

Science and Technology of Advanced Materials　Vol. 4　No. 6　p. 539-544　2003/11/01　Research paper (scientific journal)

Domain-controlled polymer alloy composed of segmented polyurethane and phospholipid polymer for biomedical applications

Ogawa Ryo, Watanabe Junji, Ishihara Kazuhiko

Science and Technology of Advanced Materials　Vol. 4　No. 6　p. 523-530　2003/11/01　Research paper (scientific journal)

Antifouling blood purification membrane composed of cellulose acetate and phospholipid polymer

Ye Sang Ho, Watanabe Junji, Iwasaki Yasuhiko, Ishihara Kazuhiko

Biomaterials　Vol. 24　No. 23　p. 4143-4152　2003/10/01　Research paper (scientific journal)

Stabilizing effect of artificial stabilizers for binding activity of QCM immunosensors

Park Jong Won, Kurosawa Shigeru, Aizawa Hidenobu, Wakida Shin Ichi, Yamada Satoshi, Ishihara Kazuhiko

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control　Vol. 50　No. 10　p. 1234-1235　2003/10/01

Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high surface mobility

Iwasaki Yasuhiko, Yamasaki Akira, Ishihara Kazuhiko

Biomaterials　Vol. 24　No. 20　p. 3599-3604　2003/09/01　Research paper (scientific journal)

Properties of blend films composed of phospholipid polymer and photocrosslinkable PVA

Shindo Yoichi, Setoguchi Taichi, Fukumoto Kikuko, Ishihara Kazuhiko, Adachi Daisaku, Inoue Kazuo

Journal of Photopolymer Science and Technology　Vol. 16　No. 2　p. 217-218　2003/07/25　Research paper (scientific journal)

Bioinspired polymer surfaces for prevention of bioresponse

Ishihara Kazuhiko, Watanabe Junji, Iwasaki Yasuhiko

Materials Science Forum　Vol. 426-432　No. 4　p. 3171-3176　2003/07/18

Comparison of stabilizing effect of stabilizers for immobilized antibodies on QCM immunosensors

Park Jong Won, Kurosawa Shigeru, Aizawa Hidenobu, Wakida Shin Ichi, Yamada Satoshi, Ishihara Kazuhiko

Sensors and Actuators, B: Chemical　Vol. 91　No. 1-3　p. 158-162　2003/06/01　Research paper (scientific journal)

Biodegradable phosphorylcholine polymer hydrogels cross-linked with vinyl-functionalized polyphosphate

Iwasaki Yasuhiko, Komatsu Shinpei, Narita Tadashi, Akiyoshi Kazunari, Ishihara Kazuhiko

Macromolecular Bioscience　Vol. 3　No. 5　p. 238-242　2003/05/15　Research paper (scientific journal)

Enhanced solubility of paclitaxel using water-soluble and biocompatible 2-methacryloyloxyethyl phosphorylcholine polymers

Tomohiro Konno, Junji Watanabe, Kazuhiko Ishihara

Journal of Biomedical Materials Research Part A　Vol. 65A　No. 2　p. 209-214　2003/05/01　Research paper (scientific journal)

Enhanced solubility of paclitaxel using water-soluble and biocompatible 2-methacryloyloxyethyl phosphorylcholine polymers

Konno Tomohiro, Watanabe Junji, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 65　No. 2　p. 209-214　2003/05/01

Surface mobility of polymers having phosphorylcholine groups connected with various bridging units and their protein adsorption-resistance properties

Yamasaki Akira, Imamura Yousuke, Kurita Kimio, Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 28　No. 1　p. 53-62　2003/04/01　Research paper (scientific journal)

Suppression of the inflammatory response from adherent cells on phospholipid polymers

Sawada Shin Ichi, Sakaki Shujiro, Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Biomedical Materials Research - Part A　Vol. 64　No. 3　p. 411-416　2003/03/01　Research paper (scientific journal)

Phosphorylcholine and poly(D,L-lactic acid) containing copolymers as substrates for cell adhesion

Watanabe Junji, Ishihara Kazuhiko

Artificial Organs　Vol. 27　No. 3　p. 242-248　2003/03/01　Research paper (scientific journal)

Higher water intrusion property on novel porous matrix composed of bioinspired polymer stereocomplex for tissue engineering

Watanabe Junji, Ishihara Kazuhiko

Chemistry Letters　Vol. 32　No. 2　p. 192-193　2003/02/05　Research paper (scientific journal)

Synthesis of vinyl-functionalized polyphosphate and preparation of the biodegradable hydrogel with 2-methacryloyloxyethyl phosphorylcholine.

Iwasaki, Y, Nakagawa, C, Komatsu, S, Akiyoshi, K, Ishihara, K

Abstracts of Papers of the American Chemical Society　Vol. 226　2003　Research paper (scientific journal)

Biocompatible polymer alloy with phospholipid polymer as green biomaterials.

Ishihara, K, Nishiuchi, D, Watanabe, J, Iwasaki, Y

Abstracts of Papers of the American Chemical Society　Vol. 226　2003　Research paper (scientific journal)

Nonthrombogenic hemodialyzer with MPC copolymer

Iwasaki Y, Nakabayashi N, Ishihara K

Advances in Science and Technology　Vol. 41(Materials in Clinical Appli　2003

Improvement of platelet compatibility of blood filtration devices with a phospholipid polymer having high surface mobility

Iwasaki Y, Yamasaki A, Ishihara K

Biomaterials　Vol. 24, 3599-3604　2003

Biodegradable phosphorylcholine-hydrogel consist of polyphosphate cross-linking reagents

Iwasaki Y, Komatsu S, Narita T, Ishihara K, Akiyoshi K

Macromol Biosci　Vol. 3, 238-242　2003

Molecular recognition of alcohol by volume phase transition of cross-linked poly(2-methacryloyloxyethyl phosphorylcholine) gel

Kiritoshi Yoshihiro, Ishihara Kazuhiko

Science and Technology of Advanced Materials　Vol. 4　No. 2　p. 93-98　2003/01/01　Research paper (scientific journal)

Controlled adhesion of human lymphocytes on electrically charged polymer surface having phosphorylcholine moiety

Ito Tomomi, Iwasaki Yasuhiko, Narita Tadashi, Akiyoshi Kazunari, Ishihara Kazuhiko

Science and Technology of Advanced Materials　Vol. 4　No. 2　p. 99-104　2003/01/01　Research paper (scientific journal)

Evaluation of stabilizing effect for several monoclonal antibody immobilized quartz crystal microbalance by stabilizer reagents

Park Jong Won, Kurosawa Shigeru, Aizawa Hidenobu, Naganawa Ryuichi, Yamada Satoshi, Ishihara Kazuhiko

PROCEEDINGS OF THE 2003 IEEE INTERNATIONAL FREQUENCY CONTROL SYMPOSIUM & PDA EXHIBITION JOINTLY WITH 17TH EUROPEAN FREQUENCY AND TIME FORUM　p. 978-980　2003　Research paper (international conference proceedings)

Novel cellulose acetate membrane blended with phospholipid polymer for hemocompatible filtration system

Ye Sang Ho, Watanabe Junji, Iwasaki Yasuhiko, Ishihara Kazuhiko

Journal of Membrane Science　Vol. 210　No. 2　p. 411-421　2002/12/15　Research paper (scientific journal)

Pressure-induced change in permeation of insulin through a polymer alloy membrane for an implantable insulin pump

Uchiyama Tomoaki, Watanabe Junji, Ishihara Kazuhiko

Journal of Membrane Science　Vol. 210　No. 2　p. 423-431　2002/12/15　Research paper (scientific journal)

Protein Adsorption-Resistant Hollow Fibers for Blood Purification

Kazuhiko Ishihara, Takashi Hasegawa, Junji Watanabe, Yasuhiko Iwasaki

Artificial Organs　Vol. 26　No. 12　p. 1014-1019　2002/12/01　Research paper (scientific journal)

Protein adsorption-resistant hollow fibers for blood purification

Ishihara Kazuhiko, Hasegawa Takashi, Watanabe Junji, Iwasaki Yasuhiko

Artificial Organs　Vol. 26　No. 12　p. 1014-1019　2002/12/01　Research paper (scientific journal)

Physical properties and blood compatibility of surface-modified segmented polyurethane by semi-interpenetrating polymer networks with a phospholipid polymer

Morimoto Nobuyuki, Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Biomaterials　Vol. 23　No. 24　p. 4881-4887　2002/12/01　Research paper (scientific journal)

Spiral vortex ventricular assist device

Iwasaki Kiyotaka, Umezu Mitsuo, Chun-Xiu Ye, Nugent Allen, Nakamura Takao, Arita Makoto, Yi Qian, Tanaka Takashi, Imachi Kou, Ishihara Kazuhiko, Chang Victor

SYSTEM SIMULATION AND SCIENTIFIC COMPUTING (SHANGHAI), VOLS I AND II　p. 1035-1039　2002/12/01　Research paper (international conference proceedings)

A challenge to develop an inexpensive "spiral vortex pump"

Tsujimoto Tomohiro, Iwasaki Kiyotaka, Saeki Wataru, Yoshida Kei, Arita Makoto, Umezu Mitsuo, Qian Yi, Ye Chun Xiu, Imachi Kou, Ishihara Kazuhiko, Tanaka Takashi

SYSTEM SIMULATION AND SCIENTIFIC COMPUTING (SHANGHAI), VOLS I AND II　p. 1040-1044　2002/12/01　Research paper (international conference proceedings)

pH-modulated release of insulin entrapped in a spontaneously formed hydrogel system composed of two water-soluble phospholipid polymers

Nam Kwang Woo, Watanabe Junji, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 13　No. 11　p. 1259-1269　2002/12/01　Research paper (scientific journal)

Thermal property and processability of elastomeric polymer alloy composed of segmented polyurethane and phospholipid polymer

Ogawa Ryo, Iwasaki Yasuhiko, Ishihara Kazuhiko

Journal of Biomedical Materials Research　Vol. 62　No. 2　p. 214-221　2002/11/01　Research paper (scientific journal)

Cell adhesion of morphology in porous scaffold based on enantiomeric poly(lactic acid) graft-type phospholipid polymers

Watanabe Junji, Eriguchi Takahisa, Ishihara Kazuhiko

Biomacromolecules　Vol. 3　No. 6　p. 1375-1383　2002/11/01　Research paper (scientific journal)

Biocompatible polymer alloy membrane for implantable artificial pancreas

Uchiyama Tomoaki, Watanabe Junji, Ishihara Kazuhiko

Journal of Membrane Science　Vol. 208　No. 1-2　p. 39-48　2002/10/01　Research paper (scientific journal)

Stereocomplex formation by enantiomeric poly(lactic acid) graft-type phospholipid polymers for tissue engineering

Watanabe Junji, Eriguchi Takahisa, Ishihara Kazuhiko

Biomacromolecules　Vol. 3　No. 5　p. 1109-1114　2002/09/01　Research paper (scientific journal)

Reduction of surface-induced inflammatory reaction on PLGA/MPC polymer blend

Iwasaki Yasuhiko, Sawada Shin Ichi, Ishihara Kazuhiko, Khang Gilson, Lee Hai Bang

Biomaterials　Vol. 23　No. 18　p. 3897-3903　2002/08/10　Research paper (scientific journal)

Stabilized liposomes with phospholipid polymers and their interactions with blood cells

Ishihara Kazuhiko, Tsujino Rieko, Hamada Mika, Toyoda Noriko, Iwasaki Yasuhiko

Colloids and Surfaces B: Biointerfaces　Vol. 25　No. 4　p. 325-333　2002/08/01　Research paper (scientific journal)

Importance of a biofouling-resistant phospholipid polymer to create a heparinized blood-compatible surface

Iwasaki Yasuhiko, Shibata Naoya, Ninomiya Madoka, Kurita Kimio, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 13　No. 3　p. 323-335　2002/07/08　Research paper (scientific journal)

リン脂質ポリマーを修飾したステンレス鋼表面の安定性と血液適合性.

森本 展行, 佐藤 育恵, 渡辺 昭彦, 中林 宣男, 岩崎 泰彦, 石原 一彦

高分子論文集　Vol. 59　No. 7　p. 432-437　2002/07　Research paper (scientific journal)

Beneficial effects of synthetic phospholipid polymer, poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate), on stratum corneum function

Kanekura T, Nagata Y, Miyoshi H, Ishihara K, Nakabayashi N, Kanzaki T

Clinical and Experimental Dermatology　Vol. 27　No. 3　p. 230-234　2002/06/26　Research paper (scientific journal)

Preparation of blood-compatible hollow fibers from a polymer alloy composed of polysulfone and 2-methacryloyloxyethyl phosphorylcholine polymer

Hasegawa Takashi, Iwasaki Yasuhiko, Ishihara Kazuhiko

Journal of Biomedical Materials Research　Vol. 63　No. 3　p. 333-341　2002/05/27　Research paper (scientific journal)

Preparation of cross-linked biocompatible poly(2-methacryloyloxyethyl phosphorylcholine) gel and its strange swelling behavior in water/ethanol mixture

Kiritoshi Yoshihiro, Ishihara Kazuhiko

Journal of Biomaterials Science, Polymer Edition　Vol. 13　No. 2　p. 213-224　2002/05/15　Research paper (scientific journal)

The vascular prosthesis without pseudointima prepared by antithrombogenic phospholipid polymer

Yoneyama Toshikazu, Sugihara Ken Ichi, Ishihara Kazuhiko, Iwasaki Yasuhiko, Nakabayashi Nobuo

Biomaterials　Vol. 23　No. 6　p. 1455-1459　2002/03/15　Research paper (scientific journal)

Characterization of the spontaneously forming hydrogels composed of water-soluble phospholipid polymers

Nam Kwang Woo, Watanabe Junji, Ishihara Kazuhiko

Biomacromolecules　Vol. 3　No. 1　p. 100-105　2002/02/13　Research paper (scientific journal)

Coating stability and blood compatibility of stainless steel surface modified with phospholipid polymer

Morimoto Nobuyuki, Sato Ikue, Watanabe Akihiko, Nakabayashi Nobuo, Iwasaki Yasuhiko, Ishihara Kazuhiko

Kobunshi Ronbunshu　Vol. 59　No. 7　p. 432-437　2002/01/01　Research paper (scientific journal)

Biocompatibility of Poly(MPC-co-EHMA)/Poly(L-lactide-co-glycolide) Blends

Khang Gilson, Choi Myoung Kyu, Rhee John M, Lee Sang Jin, Lee Hai Bang, Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Korea Polymer Journal　Vol. 9　No. 2　p. 107-115　2001/12/01　Research paper (scientific journal)

Preservation of platelet function on 2-methacryloyloxyethyl phosphorylcholine-graft polymer as compared to various water-soluble graft polymers

Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Biomedical Materials Research　Vol. 57　No. 1　p. 72-78　2001/07/30　Research paper (scientific journal)

Preparation of nanoparticles composed with bioinspired 2-methacryloyloxyethyl phosphorylcholine polymer

Konno Tomohiro, Kurita Kimio, Iwasaki Yasuhiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Biomaterials　Vol. 22　No. 13　p. 1883-1889　2001/07/04　Research paper (scientific journal)

Electroosmosis injection of blood serum into biocompatible microcapillary chip fabricated on quartz plate

Oki Akio, Adachi Sakuichiro, Takamura Yuzuru, Ishihara Kazuhiko, Ogawa Hiroki, Ito Yoshitaka, Ichiki Takanori, Horiike Yasuhiro

Electrophoresis　Vol. 22　No. 2　p. 341-347　2001/02/19　Research paper (international conference proceedings)

Preparation and performance of protein-adsorption-resistant asymmetric porous membrane composed of polysulfone/phospholipid polymer blend

Hasegawa Takashi, Iwasaki Yasuhiko, Ishihara Kazuhiko

Biomaterials　Vol. 22　No. 3　p. 243-251　2001/02/01　Research paper (scientific journal)

Molecular design and preparation of bioinspired phospholipid polymer as novel biomaterials.

Ishihara, K, Iwasaki, Y

Abstracts of Papers of the American Chemical Society　Vol. 222　2001　Research paper (scientific journal)

Effect of semi-IPN modification of phospholipid polymer on physical properties and biocompatibility of segmented polyurethane.

Iwasaki, Y, Morimoto, N, Ishihara, K

Abstracts of Papers of the American Chemical Society　Vol. 222　2001　Research paper (scientific journal)

Preparation of performance of protein adsorption resistance asymmetric porous membrane by polysulfone/phospholipid polymer blend

Hasegawa T, Iwasaki Y, Ishihara K

Biomaterials　Vol. 22(3):243-251　2001

Phospholipid polymer biomaterials for making ventricular assist devices

Ishihara K, Iwasaki Y, Nojiri C

Journal of Congestive Heart Failure and Circulatory Support　Vol. 1　No. 4　p. 265-270　2000/12/01

Preparation of blood-compatible nanoparticles bearing phosphorylcholine group

Ishihara Kazuhiko, Konno Tomohiro, Kurita Kimio, Iwasaki Yasuhiko, Nakabayashi Nobuo

ACS Symposium Series　Vol. 752　p. 417-427　2000/12/01

Polymeric lipid nanosphere composed of hemocompatible phospholipid polymers as drug carrier

Ishihara Kazuhiko

ACS Symposium Series　Vol. 752　p. 324-334　2000/12/01

Raman spectroscopic study on the structure of water in aqueous polyelectrolyte solutions

Kitano Hiromi, Sudo Kurao, Ichikawa Ken, Ide Makoto, Ishihara Kazuhiko

Journal of Physical Chemistry B　Vol. 104　No. 47　p. 11425-11429　2000/11/30

Bioinspired phospholipid polymer biomaterials for making high performance artificial organs

Ishihara K

Science and Technology of Advanced Materials　Vol. 1　No. 3　p. 131-138　2000/09/01　Research paper (scientific journal)

Graft copolymers having hydrophobic backbone and hydrophilic branches. XXX. Preparation of polystyrene-core nanospheres having a poly(2-methacryloyloxyethyl phosphorylcholine) corona

Uchida Toshiro, Furuzono Tsutomu, Ishihara Kazuhiko, Nakabavashi Nobuo, Akashi Mitsuru

Journal of Polymer Science, Part A: Polymer Chemistry　Vol. 38　No. 17　p. 3052-3058　2000/09/01　Research paper (scientific journal)

Prevention of fibrous layer formation between bone and adhesive bone cement

Sakai Tomoko, Morita Sadao, Shinomiya Kennichi, Watanabe Akihiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Biomedical Materials Research　Vol. 52　No. 1　p. 24-29　2000/08/01　Research paper (scientific journal)

In vivo evaluation of the bond strength of adhesive 4-META/MMA-TBB bone cement under weight-bearing conditions

Sakai Tomoko, Morita Sadao, Shinomiya Ken Ichi, Watanabe Akihiko, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Biomedical Materials Research　Vol. 52　No. 1　p. 128-134　2000/08/01　Research paper (scientific journal)

Phospholipid polymer - DNA conjugate for gene delivery

Ishihara Kazuhiko, Sakaki Shujiro

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY　Vol. 219　p. 1014-1015　2000/03

Glucose measurement in blood serum injected by electroosmosis into phospholipid polymer coated microcapillary

A Oki, S Adachi, Y Takamura, K Ishihara, K Kataoka, T Ichiki, Y Horiike

MICRO TOTAL ANALYSIS SYSTEMS 2000, PROCEEDINGS　p. 403-406　2000　Research paper (international conference proceedings)

Biocompatibility of MPC

Nowak Tanja, Nishida Kenro, Shimoda Seiya, Konno Yumi, Ichinose Kenshi, Sakakida Michiharu, Shichiri Motoaki, Nakabayashi Nobuo, Ishihara Kazuhiko

Journal of Artificial Organs　Vol. 3　No. 1　p. 39-46　2000/01/01　Research paper (scientific journal)

Development of elemental technologies for fabricating the health care chip

Oki A, Adachi S, Takamura Y, Ishihara K, Ogawa H, Ichiki T, Horiike Y

MICROPROCESSES AND NANOTECHNOLOGY 2000, DIGEST OF PAPERS　p. 70-71　2000　Research paper (international conference proceedings)

Preparation of blood compatible nanoparticles bearing phospholipid polar group as a novel drug carrier

Konno T, Kurita K, Iwasaki Y, Nakabayashi N, Ishihara K

Proceedings of the Controlled Release Society　No. 26　p. 1040-1041　1999/12/07

Multifunctional Biocompatible Membrane and Its Application to Fabricate a Miniaturized Glucose Sensor with Potential for Use in Vivo

Chen Chien Yuan, Ishihara Kazuhiko, Nakabayashi Nobuo, Tamiya Eiichi, Karube Isao

Biomedical Microdevices　Vol. 1　No. 2　p. 155-166　1999/12/01　Research paper (scientific journal)

Hemocompatible drug carrier composed of water-soluble phospholipid polymers

Ishihara Kazuhiko

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY　Vol. 217　p. 281-282　1999/03

Preparation of blood compatible nanoparticles bearing phosphorylcholine group

Ishihara Kazuhiko, Konno Tomohiro, Kurita Kimio, Iwasaki Yasuhiko, Nakabayashi Nobuo

Abstracts of Papers of the American Chemical Society　Vol. 217　p. 283-284　1999/03　Research paper (scientific journal)

Drug release from segmented polyurethane containing blood compatible phospholipid polymer as a polymeric additive

Ishihara K, Iwasaki Y

Proceedings of the Controlled Release Society　No. 26　p. 114-115　1999/01/01

Biocompatibility of MPC

Shimoda S, Sakakida M, Ichinose K, Nishida K, Konno Y, Shichiri M, Ishihara K, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 28　No. 1　p. 156-160　1999/01/01

Biocompatible Microdialysis Hollow-Fiber Probes for Long-Term in Vivo Glucose Monitoring

Ishihara Kazuhiko, Nakabayashi Nobuo, Sakakida Michiharu, Nishida Kenro, Shichiri Motoaki

ACS Symposium Series　Vol. 690　p. 24-33　1998/12/01　Research paper (scientific journal)

Short-term in vivo evaluation of small-diameter vascular prosthesis composed of segmented poly(etherurethane)/2-methacryloyloxyethyl phosphorylcholine polymer blend

Yoneyama Toshikazu, Ishihara Kazuhiko, Nakabayashi Nobuo, Ito Masashi, Mishima Yoshio

Journal of Biomedical Materials Research　Vol. 43　No. 1　p. 15-20　1998/03/01　Research paper (scientific journal)

Relationship between blood compatibility and nonthrombogenic polymer surfaces

Uchida Katsumi, Waki Masahiro, Sakai Kiyotaka, Nojiri Chisato, Kido Takayuki, Sugiyama Tomoko, Ishihara Kazuhiko, Nakabayashi Nobuo

Kagaku Kogaku Ronbunshu　Vol. 24　No. 2　p. 220-221　1998/03/01　Research paper (scientific journal)

Water-soluble phospholipid polymers as novel synthetic blocking agent.

Ishihara, K, Iwasaki, Y, Sakaki, S, Nakabayashi, N

Abstracts of Papers of the American Chemical Society　Vol. 216　1998　Research paper (scientific journal)

Evaluation of the frictional properties of an elastomer with enhanced lipid-adsorbing ability

Williams Hi P. F, Iwasaki Y, Ishihara K

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine　Vol. 211　No. 5　p. 359-368　1997/12/01　Research paper (scientific journal)

Reduction of surface-induced platelet activation on phospholipid polymer

Iwasaki Yasuhiko, Mikami Asako, Kurita Kimio, Yui Nobuhiko, Ishihara Kazuhiko, Nakabayashi Nobuo

Journal of Biomedical Materials Research　Vol. 36　No. 4　p. 508-515　1997/09/15　Research paper (scientific journal)

Polymeric lipid nanosphere as a novel drug carrier through blood stream

Ishihara K, Nakabayashi N

Proceedings of the Controlled Release Society　No. 24　p. 465-466　1997/08/22

Stabilization of liposomes attached to polymer surfaces having phosphorylcholine groups

Iwasaki Yasuhiko, Tanaka Shinobu, Hara Masahiko, Ishihara Kazuhiko, Nakabayashi Nobuo

Journal of Colloid and Interface Science　Vol. 192　No. 2　p. 432-439　1997/08/15　Research paper (scientific journal)

Synthetic endothelial surface with phospholipid polymer

Iwasaki Y, Ishihara K, Nakabayashi N

1996/12/01

Boundary lubricating elastomer for physiological bearing applications. II. Friction tests

Williams P. F, Gilbert J. A, Powell G. L, Ishihara K, Nakabayashi N, LaBerge M

1996/12/01

Development of a miniaturized glucose monitoring system combined a needle-type glucose sensor and a microdialysis hollow-fiber probe covered with a newly designed biocompatible membrane

Sakakida M, Nishida K, Ichinose K, Konno Y, Simoda S, Uemura T, Uehara M, Shichiri M, Ishihara K, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 25　No. 1　p. 139-143　1996/12/01

Improved blood compatibility of segmented polyurethane by phospholipid polymeric additive

Nakabayashi N, Tanaka S, Iwasaki Y, Ishihara K

Journal of Biomedical Materials Research　Vol. 32　No. 3　1996/12/01　Research paper (scientific journal)

Controlled release system for bone morphogenetic protein

Isobe M, Yamazaki Y, Ishihara K, Nakabayashi N, Amagasa T

1996/12/01

Extraordinary water structure in biocompatible phospholipid polymers

Ishihara K, Ueda T, Nomura H, Kurita K, Nakabayashi N

1996/12/01

In vitro evaluation of the ability of a phospholipid polymer to reduce fibroblast attachment

Newton B, Watanabe A, Iwasaki Y, Williams P. F, Gilbert J. A, LaBerge M, Ishihara K, Nakabayashi N

1996/12/01

Novel surface modifier for blood compatible cellulose hemodialysis membrane

Miyano T, Kurita K, Ishihara K, Nakabayashi N

1996/12/01

Selective adhesion and spontaneous fusion of platelets on polyion complex composed of phospholipid polymers

K Ishihara, H Inoue, K Kurita, N Nakabayashi

ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS　p. 227-228　1996　Research paper (international conference proceedings)

Hemocompatible cellulose dialysis membrane modified with phospholipid polymer

K Ishihara, N Nakabayashi

ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS　p. 213-214　1996　Research paper (international conference proceedings)

MPC膜被覆ホローファイバーを用いたマイクロダイアリシス・サンプリング法による血糖モニターシステムの開発．

榊田典治, 西田健朗, 一ノ瀬賢司, 今野由美, 下田誠也, 上村毅郎, 上原昌哉, 七里元亮, 石原一彦, 中林宣男

人工臓器　Vol. 25　p. 139-143　1996/01

MPC膜被覆フェロセン付加微小針型ブドウ糖センサを組み込んだ携帯型人工膵島による長期臨床応用．

西田健朗, 榊田典治, 一ノ瀬賢司, 下田誠也, 今野由美, 上村毅郎, 上原昌哉, 七里元亮, 石原一彦, 中林宣男

人工臓器　Vol. 25　p. 144-148　1996/01

Development of a haemocompatible intravascular pO2 sensor using newly sythesised phospholipid polymers

Tanaka S, Ishihara K, Nakabayashi N, Yamakoshi K. I, Rolfe P

Japanese Journal of Artificial Organs　Vol. 25　No. 1　p. 234-238　1996/01/01

Nonthrombogenic hemodialysis membrane

Ishihara K

Japanese Journal of Artificial Organs　Vol. 25　No. 4　p. 778-784　1996/01/01

Nonthrombogenic polymers - Designs and evaluation

Nakabayashi Nobuo, Ishihara Kazuhiko

Macromolecular Symposia　Vol. 101　p. 405-412　1996/01/01　Research paper (scientific journal)

Preparation of phospholipid polymers and their properties as polymer hydrogel membranes

Ishihara K, Nakabayashi N

Proceedings of the Controlled Release Society　No. 23　p. 787-788　1996/01/01　Research paper (international conference proceedings)

Clinical application of wearable artificial endocrine pancreas with ferrocene-mediated needle-type glucose sensor covered with newly designed biocompatible membrane

Nishida K, Sakakida M, Ichinose K, Shimoda S, Konno Y, Uemura T, Uehara M, Shichiri M, Ishihara K, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 25　No. 1　p. 144-148　1996/01/01

MPC膜被覆フェロセン付加微小針型ブドウ糖センサを組み込んだ携帯型人工膵島による長期臨床応用．

西田健朗, 榊田典治, 一ノ瀬賢司, 下田誠也, 上村毅郎, 梶原研一郎, 宮田高雄, 七里元亮, 石原一彦, 中林宣男

人工臓器　Vol. 24　p. 754-759　1995/04

MPC膜被覆ホローファイバーを用いたマイクロダイアリシス・サンプリング法による血糖モニターシステムの開発．

榊田典治, 一ノ瀬賢司, 西田健朗, 下田誠也, 上村毅郎, 梶原研一郎, 宮田高雄, 七里元亮, 石原一彦, 中林宣男

人工臓器　Vol. 24　p. 748-753　1995/03

Reduced protein adsorption on polymer surface covered with a self-assembled biomimetic membrane

K Ishihara, N Nakabayashi

PROTEINS AT INTERFACES II　Vol. 602　p. 385-394　1995　Research paper (scientific journal)

Ex vivo blood compatibility of polymers having phospholipid polar group

Iwasaki Y, Kurita K, Tanaka S, Ishihara K, Nakabayashi N

J Jpn Soc Biomater　Vol. 13, 62-70　1995　Research paper (scientific journal)

Stabilization of liposome with blood compatible water-soluble phospholipid polymer

Ishihara K, Tsujino R, Hamada M, Nakabayashi N

Proceedings of the Controlled Release Society　No. 22　p. 188-189　1995/01/01

Clinical application of wearable artificial endocrine pancreas with ferrocene-mediated needle-type glucose sensor covered with newly designed biocompatible membrane

Nishida K, Sakakida M, Ichinose K, Uehara M, Uemura T, Kajiwara K, Miyata T, Shichiri M, Ishihara K, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 24　No. 3　p. 754-759　1995/01/01

Effect of methylene chain length in phospholipid moiety on blood compatibility of phospholipid polymers

Iwasaki Y, Kurita K, Ishihara K, Nakabayashi N

Journal of Biomaterials Science, Polymer Edition　Vol. 6　No. 5　p. 447-461　1995　Research paper (scientific journal)

Effect of methylene chain length in phospholipid moiety on blood compatibility of phospholipid polymers.

Iwasaki Y, Kurita K, Ishihara K, Nakabayashi N

Journal of biomaterials science. Polymer edition　Vol. 6　No. 5　p. 447-461　1994/12/01　Research paper (scientific journal)

Selective adhesion of platelets on a polyion complex composed of phospholipid polymers containing sulfonate groups and quarternary ammonium groups

Ishihara K, Inoue H, Kurita K, Nakabayashi N

Journal of Biomedical Materials Research　Vol. 28　No. 11　p. 1347-1355　1994/11/01　Research paper (scientific journal)

NEW BIOCOMPATIBLE POLYMER - APPLICATION FOR IMPLANTABLE GLUCOSE SENSOR

K ISHIHARA, N NAKABAYASHI, K NISHIDA, M SAKAKIDA, M SHICHIRI

DIAGNOSTIC BIOSENSOR POLYMERS　Vol. 556　p. 194-210　1994　Research paper (scientific journal)

Development of ferrocene-mediated needle-type glucose sensor covered with MPC membrane. Examination of biocompatibility of MPC membrane

Nishida K, Sakakida M, Ichinose K, Hashiguchi Y, Uehara M, Uemura T, Kajiwara K, Shichiri M, Ishihara K, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 23　No. 2　p. 485-489　1994/01/01

Blood compatible cellulose hollow fibers modified with MPC polymer

Ishihara K, Watanabe A, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 23　No. 3　p. 654-659　1994/01/01

Improvement of hemocompatibility on a cellulose dialysis membrane with a novel biomedical polymer having a phospholipid polar group

Ishihara K, Fukumoto K, Miyazaki H, Nakabayashi N

Artificial Organs　Vol. 18　No. 8　p. 559-564　1994/01/01　Research paper (scientific journal)

Improvement of haemocompatibility of activated charcoal for direct haemoperfusion using a newly prepared coating polymer having phospholipid polar group

Tanaka S, Ishihara K, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 23　No. 3　p. 721-725　1994/01/01

Assessment of adsorption of liposomes on a phospholipid polymer surface using a quartz crystal microbalance

Tanaka Shinobu, Iwasaki Yasuhiko, Ishihara Kazuhiko, Nakabayashi Nobuo

Macromolecular Rapid Communications　Vol. 15　No. 4　p. 319-326　1994　Research paper (scientific journal)

DESIGNING BIOCOMPATIBLE MATERIALS

K ISHIHARA, N NAKABAYASHI, K NISHIDA, M SAKAKIDA, M SHICHIRI

CHEMTECH　Vol. 23　No. 10　p. 19-25　1993/10　Research paper (scientific journal)

Effects of phospholipid adsorption on nonthrombogenicity of polymer with phospholipid polar group

Ishihara K, Oshida H, Endo Y, Watanabe A, Ueda T, Nakabayashi N

Journal of Biomedical Materials Research　Vol. 27　No. 10　p. 1309-1314　1993/10/01　Research paper (scientific journal)

Synthesis of Protein Adsorption Resistant Polymers and Their Application for Biomedical Membranes.

Ishihara Kazuhiko

MEMBRANE　Vol. 18　No. 2　p. 107-116　1993

Long-term clinical applications of a wearable artificial endocrine pancreas with a newly designed needle-type glucose sensor

Nishida K, Sakakida M, Hashiguchi Y, Uehara M, Uemura T, Kajiwara K, Shichiri M, Ishihara K, Nakabayashi N

Japanese Journal of Artificial Organs　Vol. 22　No. 3　p. 1090-1095　1993/01/01

Preparation of 2-methacryloyloxyethyl phosphorylcholine copolymers with alkyl methacrylates and their blood compatibility

Ueda Tomoko, Oshida Hiroko, Kurita Kimio, Ishihara Kazuhiko, Nakabayashi Nobuo

Polymer Journal　Vol. 24　No. 11　p. 1259-1269　1992/12/01　Research paper (scientific journal)

Hemocompatibility of human whole blood on polymers with a phospholipid polar group and its mechanism

Ishihara K, Oshida H, Endo Y, Ueda T, Watanabe A, Nakabayashi N

Journal of Biomedical Materials Research　Vol. 26　No. 12　p. 1543-1552　1992/12/01　Research paper (scientific journal)

A biocompatible needle-type glucose sensor based on platinum-electroplated carbon electrode

Chen Chien Yuan, Tamiya Eiichi, Ishihara Kazuhiko, Kosugi Yukio, Su Yuan Chi, Nakabayashi Nobuo, Karube Isao

Applied Biochemistry and Biotechnology　Vol. 36　No. 3　p. 211-226　1992/09/01　Research paper (scientific journal)

Temperature effect on drug release from poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butylmethacrylate) membrane.

Ueda Tomoko, Ishihara Kazuhiko, Nakabayashi Nobuo

MEMBRANE　Vol. 17　No. 6　p. 403-408　1992

Improvement of blood compatibility on cellulose dialysis membrane I. Grafting of 2-methacryloyloxyethyl phosphorylcholine on to a cellulose membrane surface

Ishihara Kazuhiko, Nakabayashi Nobuo, Fukumoto Kikuko, Aoki Junji

Biomaterials　Vol. 13　No. 3　p. 145-149　1992/01/01　Research paper (scientific journal)

Synthesis and adhesion of graft copolymer with reactive group to tooth substrates

Yamamoto Takashi, Kajima Junko, Kurita Kimio, Ishihara Kazuhiko, Nakahayashi Nobuo

Kobunshi Ronbunshu　Vol. 49　No. 2　p. 119-123　1992/01/01　Research paper (scientific journal)

Improvement of blood compatibility on cellulose dialysis membrane. 2. Blood compatibility of phospholipid polymer grafted cellulose membrane

Ishihara Kazuhiko, Takayama Ryuichi, Nakabayashi Nobuo, Fukumoto Kikuko, Aoki Junji

Biomaterials　Vol. 13　No. 4　p. 235-239　1992/01/01　Research paper (scientific journal)

Haemocompatibility of polymer having phospholipid polar groups evaluated by monoclonal antibody method

Xi Tingfei, Tian Wenhua, Lei Xuehui, Zhao Lejun, Ishihara Kazuhiko

Biomaterials　Vol. 13　No. 6　p. 357-360　1992/01/01　Research paper (scientific journal)

Preparation and visible light polymerization of triethyleneglycol acrylate methacrylate

Saimi Yasukazu, Ishihara Kazuhiko, Nakabayashi Nobuo

Polymer Journal　Vol. 24　No. 4　p. 357-363　1992/01/01　Research paper (scientific journal)

Interaction between phospholipids and biocompatible polymers containing a phosphorylcholine moiety

Kojima Masayoshi, Ishihara Kazuhiko, Watanabe Akihiko, Nakabayashi Nobuo

Biomaterials　Vol. 12　No. 2　p. 121-124　1991/01/01　Research paper (scientific journal)

Adsorption of bilirubin by direct hemoperfusion using macroporous polymer beads

Ishihara Kazuhiko, Hayashi Eri, Watanabe Akihiko, Nakabayashi Nobuo, Akisawa Tadao, Koshikawa Syozo, Kimura Syuji, Yamamoto Yuichi

Kobunshi Ronbunshu　Vol. 48　No. 5　p. 283-288　1991/01/01　Research paper (scientific journal)

Platelet adhesion on polymers having phospholipid polar group

Ueda Tomoko, Ishihara Kazuhiko, Nakabayashi Nobuo

Kobunshi Ronbunshu　Vol. 48　No. 5　p. 289-294　1991/01/01

Mechanism of nonthrombogenicity on 2-methacryloyloxyethyl phosphorylcholine copolymers

Nakabayashi Nobuo, Ueda Tomoko, Ishihara Kazuhiko

1991/01/01

Nonthrombogenic Polymer Materials

Ueda Tomoko, Ishihara Kazuhiko, Nakabayashi Nobuo

Sen'i Gakkaishi　Vol. 47　No. 3　p. 126-132　1991　Research paper (scientific journal)

Adhesion of dental resin to tooth substrates using polymers with sulfonic acid

Yamamoto Takashi, Ishihara Kazuhiko, Nakabayashi Nobuo

Kobunshi Ronbunshu　Vol. 47　No. 8　p. 655-658　1990/12/01　Research paper (scientific journal)

Durability of bonding between 4-META/MMA-TBB resin to dentin pretreated with 10-3. The effect of 10-3 pretreating period and subsequent glutaraldehyde treatment

Takarada K, Kojima M, Ishihara K, Nakabayashi N

Shika zairyo, kikai = Journal of the Japanese Society for Dental Materials and Devices　Vol. 9　No. 6　p. 831-840　1990/11/01

NOVEL ORGANOSILICON-CONTAINING POLYMERS FOR AN OXYGEN PERMSELECTIVE MEMBRANE

Y NAGASAKI, K KUROSAWA, M SUDA, S TAKAHASHI, T TSURUTA, K ISHIHARA, Y NAGASE

MAKROMOLEKULARE CHEMIE-MACROMOLECULAR CHEMISTRY AND PHYSICS　Vol. 191　No. 9　p. 2103-2110　1990/09　Research paper (scientific journal)

THERMALLY RESPONSIVE RELEASE OF 5-FLUOROURACIL FROM A BIOCOMPATIBLE HYDROGEL MEMBRANE WITH PHOSPHOLIPID STRUCTURE

T UEDA, K ISHIHARA, N NAKABAYASHI

MAKROMOLEKULARE CHEMIE-RAPID COMMUNICATIONS　Vol. 11　No. 8　p. 345-348　1990/08　Research paper (scientific journal)

Preparation of Phospholipid Polylners and Their Properties as Polymer Hydrogel Membranes

Kazuhiko Ishihara, Tomoko Ueda, Nobuo Nakabayashi

Polymer Journal　Vol. 22　No. 5　p. 355-360　1990/05　Research paper (scientific journal)

Chemical modification of poly(substituted-acetylene). II. Pervaporation of ethanol / water mixture through poly(1-trimethylsilyl-1-propyne) / poly(dimethylsiloxane) graft copolymer membrane

Nagase Yu, Ishihara Kazuhiko, Matsui Kiyohide

Journal of Polymer Science, Part B: Polymer Physics　Vol. 28　No. 3　p. 377-386　1990/02/01　Research paper (scientific journal)

Adhesive bone cement both to bone and metals

Ishihara K, Nakabayashi N

Journal of Biomedical Materials Research　Vol. 23　No. 12　p. 1475-1482　1989/12/01　Research paper (scientific journal)

Drug release from hydrogel membrane having phospholipid structure

Ishihara Kazuhiko, Ueda Tomoko, Nakabayashi Nobuo

Kobunshi Ronbunshu　Vol. 46　No. 10　p. 591-595　1989/10/01　Research paper (scientific journal)

POLY[4-BIS(TRIMETHYLSILYL)METHYLSTYRENE] FOR AN OXYGEN-PERMEABLE MEMBRANE

Y NAGASAKI, M SUDA, T TSURUTA, K ISHIHARA, Y NAGASE

MAKROMOLEKULARE CHEMIE-RAPID COMMUNICATIONS　Vol. 10　No. 6　p. 255-258　1989/06　Research paper (scientific journal)

Polymerization ability of perfluoroalkyloxy group substituted styrene derivatives and their surface characteristics

Ishihara Kazuhiko, Kogure Rieko, Matsui Kiyohide

Kobunshi Ronbunshu　Vol. 45　No. 8　p. 653-659　1988/12/01　Research paper (scientific journal)

PERVAPORATION OF ETHANOL-WATER MIXTURE THROUGH COMPOSITE MEMBRANES COMPOSED OF STYRENE-FLUOROALKYL ACRYLATE GRAFT COPOLYMERS AND CROSS-LINKED POLYDIMETHYLSILOXANE MEMBRANE.

Ishihara Kazuhiko, Matsui Kiyohide

Journal of Applied Polymer Science　Vol. 34　No. 1　p. 437-440　1987/07/01

SEPARATION OF ETHANOL THROUGH STYRENE-DIMETHYLSILOXANE GRAFT COPOLYMER MEMBRANES BY PERVAPORATION.

Ishihara Kazuhiko, Kogure Rieko, Matsui Kiyohide

Kobunshi Ronbunshu　Vol. 43　No. 11　p. 779-785　1986/11/01　Research paper (scientific journal)

GLUCOSE-RESPONSIVE INSULIN RELEASE FROM POLYMER CAPSULE.

Ishihara Kazuhiko, Matsui Kiyohide

JOURNAL OF POLYMER SCIENCE PART C-POLYMER LETTERS　Vol. 24　No. 8　p. 413-417　1986/08/01　Research paper (scientific journal)

PERVAPORATION OF ALCOHOL WATER MIXTURES THROUGH POLY[1-(TRIMETHYLSILYL)-1-PROPYNE] MEMBRANE

K ISHIHARA, Y NAGASE, K MATSUI

MAKROMOLEKULARE CHEMIE-RAPID COMMUNICATIONS　Vol. 7　No. 2　p. 43-46　1986/02　Research paper (scientific journal)

pH-INDUCED REVERSIBLE PERMEABILITY CONTROL OF THE 4-CARBOXY ACRYLANILIDE-METHYL METHACRYLATE COPOLYMER MEMBRANE.

Ishihara Kazuhiko, Muramoto Naohiro, Fujii Hideyuki, Shinohara Isao

Journal of polymer science. Part A-1, Polymer chemistry　Vol. 23　No. 11　p. 2841-2850　1985/11/01

PREPARATION AND PERMEABILITY OF UREA-RESPONSIVE POLYMER MEMBRANE CONSISTING OF IMMOBILIZED UREASE AND POLY(AROMATIC CARBOXYLIC ACID).

Ishihara Kazuhiko, Muramoto Naohiro, Fujii Hideyuki, Shinohara Isao

Journal of polymer science. Polymer letters edition　Vol. 23　No. 10　p. 531-535　1985/10/01

DESIGN OF POLYMER MEMBRANE WITH PERMSELECTIVITY FOR WATER-ETHANOL MIXTURE. II. PREPARATION OF CROSSLINKED POLY(METHYL ACRYLATE) MEMBRANE WITH DIETHYLENE TRIAMINE AND ITS PERMSELECTIVITY.

Itoh Toshiaki, Toya Hideki, Ishihara Kazuhiko, Shinohara Isao

Journal of Applied Polymer Science　Vol. 30　No. 1　p. 179-188　1985/01/01　Research paper (scientific journal)

PHOTOINDUCED REVERSIBLE pH CHANGE IN AQUEOUS SOLUTION OF AZOAROMATIC POLY(CARBOXYLIC ACID).

Ishihara Kazuhiko, Matsuo Tohru, Tsunemitsu Katsuaki, Shinohara Isao, Negishi Naoki

Journal of polymer science. Part A-1, Polymer chemistry　Vol. 22　No. 12　p. 3687-3695　1984/12/01

Hybrid型人工すい臓 細胞保護膜への抗血せん性材料コーティングによるインスリン透過性への影響

町山 悦子, 石原 一彦, 大河 原久子, 壁井 信之, 岡野 光夫, 片岡 一則, 山田 明夫, 桜井 清久, 平田 幸正

人工臓器　Vol. 13　No. 2　p. 880-883　1984　Research paper (scientific journal)

PHOTOINDUCED SWELLING CONTROL OF AMPHIPHILIC AZOAROMATIC POLYMER MEMBRANE.

Ishihara Kazuhiko, Hamada Naoshi, Kato Shinji, Shinohara Isao

Journal of polymer science. Part A-1, Polymer chemistry　Vol. 22　No. 1　p. 121-128　1984/01/01

INSULIN PERMEATION THROUGH AMPHIPHILIC POLYMER MEMBRANES HAVING 2-HYDROXYETHYL METHACRYLATE MOIETY.

Ishihara Kazuhiko, Kobayashi Mineko, Shinohara Isao

Polymer Journal　Vol. 16　No. 8　p. 647-651　1984/01/01

GLUCOSE INDUCED PERMEATION CONTROL OF INSULIN THROUGH A COMPLEX MEMBRANE CONSISTING OF IMMOBILIZED GLUCOSE OXIDASE AND A POLY(AMINE).

Ishihara Kazuhiko, Kobayashi Mineko, Ishimaru Naoshi, Shinohara Isao

Polymer Journal　Vol. 16　No. 8　p. 625-631　1984/01/01　Research paper (scientific journal)

CONTROLLED RELEASE OF ORGANIC SUBSTANCES USING POLYMER MEMBRANE WITH RESPONSIVE FUNCTION FOR AMINO COMPOUNDS.

Ishihara Kazuhiko, Muramoto Naohiro, Shinohara Isao

Journal of Applied Polymer Science　Vol. 29　No. 1　p. 211-217　1984/01/01　Research paper (scientific journal)

Effect of antithrombogenic coating on semipermeable membrane to insulin permeability for a hybrid artificial pancreas

Machiyama E, Ishihara K, Ohgawara H

Japanese Journal of Artificial Organs　Vol. 13　No. 2　p. 880-883　1984

PERMSELECTIVITY OF LIQUID-POLYMER HYBRID MEMBRANE COMPOSED OF CARBON TETRACHLORIDE AND 2-HYDROXYETHYL ACRYLATE-ACRYLONITRILE GRAFT COPOLYMER FOR ETHANOL-WATER MIXTURE.

Itoh Toshiaki, Ohkawa Yuji, Ishihara Kazuhiko, Shinohara Isao

Polymer Journal　Vol. 15　No. 11　p. 827-834　1983/12/01　Research paper (scientific journal)

PHOTO-INDUCED CHANGE IN SURFACE FREE ENERGY OF AZOAROMATIC POLYMERS.

Ishihara Kazuhiko, Hamada Naoshi, Kato Shinji, Shinohara Isao

Journal of polymer science. Part A-1, Polymer chemistry　Vol. 21　No. 5　p. 1551-1555　1983/05/01

PREPARATION OF PHOTORESPONSIVE POLYMERIC ADSORBENT CONTAINING AMPHIPHILIC POLYMER WITH AZOBENZENE MOIETY AND ITS APPLICATION FOR CELL ADHESION CHROMATOGRAPHY.

Ishihara Kazuhiko, Kim Munsok, Shinohara Isao, Okano Teruo, Kataoka Kazunori, Sakurai Yasuhisa

Journal of Applied Polymer Science　Vol. 28　No. 4　p. 1321-1329　1983/04/01　Research paper (scientific journal)

Separation of amino acids by charge-transfer interaction chromatography in aqueous systems

Ishihara Kazuhiko, Iida Tsukasa, Muramoto Naohiro, Shinohara Isao

Journal of Chromatography A　Vol. 250　No. C　p. 119-123　1982/11/26

SEPARATION OF PROTEINS BY POLYMERIC ADSORBENTS CONTAINING AZOBENZENE MOEITY AS A LIGAND.

ISHIHARA KAZUHIKO, KATO SHINJI, SHINOHARA ISAO

J APPL POLYM SCI　Vol. V 27　No. N 11　p. 4273-4282　1982/11/01　Research paper (scientific journal)

COMPLEX FORMATION OF AMPHIPHILIC POLYMERS WITH AZO DYES AND THEIR PHOTOVISCOSITY BEHAVIOR.

Negishi Naoki, Ishihara Kazuhiko, Shinohara Isao

Journal of polymer science. Part A-1, Polymer chemistry　Vol. 20　No. 7　p. 1907-1916　1982/07/01

Preparation of polymer membranes with responsive function for amino compounds

Ishihara Kazuhiko, Muramoto Naohiro, Lida Tsukasa, Shinohara Isao

Polymer Bulletin　Vol. 7　No. 9-10　p. 457-463　1982/07/01　Research paper (scientific journal)

PHOTOCONTROLLED ADSORPTION CHROMATOGRAPHY FOR LYSOZYME USING AZOAROMATIC POLYMER.

Ishihara Kazuhiko, Negishi Naoki, Shinohara Isao

Journal of Applied Polymer Science　Vol. 27　No. 6　p. 1897-1902　1982/06/01　Research paper (scientific journal)

PHOTO-INDUCED CHANGE IN WETTABILITY AND BINDING ABILITY OF AZOAROMATIC POLYMERS.

Ishihara Kazuhiko, Okazaki Akihiko, Negishi Naoki, Kataoka Kazunori, Sakurai Yasuhisa, Okano Teruo

Journal of Applied Polymer Science　Vol. 27　No. 1　p. 239-245　1982/01/01　Research paper (scientific journal)

Cell Adhesion Chromatography by Using Photoresponsive Polymeric Adsorbents

Ishihara Kazuhiko, Kato Shinji, Shinohara Isao

KOBUNSHI RONBUNSHU　Vol. 39　No. 4　p. 271-276　1982　Research paper (scientific journal)

PHOTOREGULATED BINDING ABILITY OF AZOAROMATIC POLYMER FOR SURFACTANT.

Ishihara Kazuhiko, Negishi Naoki, Shinohara Isao

Journal of polymer science. Part A-1, Polymer chemistry　Vol. 19　No. 12　p. 3039-3046　1981/12/01

PHOTOREGULATED BINDING OF AMPHIPATHIC PROTEINS TO AZOAROMATIC POLYMER

N NEGISHI, K ISHIHARA, SHINOHARA, I, T OKANO, K KATAOKA, Y SAKURAI, T AKAIKE

CHEMISTRY LETTERS　No. 5　p. 681-684　1981　Research paper (scientific journal)

REGULATION OF BINDING AND RELEASING OF CEPHALOSPORINS BY PHOTORESPONSIVE POLYMERIC ADSORBENT

N NEGISHI, K ISHIHARA, SHINOHARA, I, T OKANO, K KATAOKA, Y SAKURAI

MAKROMOLEKULARE CHEMIE-RAPID COMMUNICATIONS　Vol. 2　No. 1　p. 95-98　1981　Research paper (scientific journal)

Photo_-. Induced reversible change on wettability on photochromic polymer surface

Negishi Naoki, Tsunemitsu Katsuaki, Ishihara Kazuhiko, Shinohara Isao, Okano Teruo, Kataoka Kazunori, Akaike Toshihiro, Sakurai Yasuhisa

KOBUNSHI RONBUNSHU　Vol. 37　No. 4　p. 287-291　1980　Research paper (scientific journal)