顔写真

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TAKEKAWA Norihiro
竹川 宜宏
TAKEKAWA Norihiro
竹川 宜宏
Graduate School of Science Department of Macromolecular Science,Assistant Professor

Research History 4

  1. 2019/04 - Present
    Osaka University Graduate School of Science

  2. 2020/02 - 2022/01
    RIKEN

  3. 2016/04 - 2019/03
    Osaka University Graduate School of Science

  4. 2013/04 - 2016/03
    Nagoya University Graduate School of Science

Education 2

  1. 名古屋大学 大学院 理学研究科 生命理学専攻

    2011/04 - 2015/08

  2. Nagoya University School of Science

    2007/04 - 2011/03

Professional Memberships 3

  1. 日本蛋白質科学会

  2. THE JAPANESE BIOCHEMICAL SOCIETY

  3. THE BIOPHYSICAL SOCIETY OF JAPAN

Research Areas 4

  1. Life sciences / Biophysics /

  2. Life sciences / Functional biochemistry /

  3. Life sciences / Structural biochemistry /

  4. Life sciences / Molecular biology /

Awards 5

  1. 第91回日本生化学会大会 若手優秀発表賞

    竹川 宜宏 2018/09

  2. 第6回 日本学術振興会 育志賞

    竹川 宜宏 2016/03

  3. 名古屋大学学術奨励賞

    竹川 宜宏 2015/06

  4. 日本生化学会 JB論文賞

    竹川 宜宏 2014/09

  5. 名古屋大学大学院理学研究科顕彰

    竹川 宜宏 2013/03

Papers 33

  1. Cryo-EM Structure of the Flagellar Motor Complex from Paenibacillus sp. TCA20

    Sakura Onoe, Tatsuro Nishikino, Miki Kinoshita, Norihiro Takekawa, Tohru Minamino, Katsumi Imada, Keiichi Namba, Jun-ichi Kishikawa, Takayuki Kato

    Biomolecules Vol. 15 No. 3 2025/03/18 Research paper (scientific journal)

    Publisher: MDPI AG
  2. Sodium-Dependent Conformational Change in Flagellar Stator Protein MotS from Bacillus subtilis

    Norihiro Takekawa, Ayaka Yamaguchi, Koki Nishiuchi, Maria Uehori, Miki Kinoshita, Tohru Minamino, Katsumi Imada

    Biomolecules Vol. 15 No. 2 2025/02/18 Research paper (scientific journal)

    Publisher: MDPI AG
  3. V 型線毛蛋白質の結晶化と予備的結晶学研究

    小島 嶺, 庄子 幹郎, 柴田 敏史, 竹川 宜宏, 今田 勝巳

    SPring-8/SACLA利用研究成果集 Vol. 13 No. 1 p. 29-31 2025/01 Research paper (scientific journal)

  4. Structural insight into sodium ion pathway in the bacterial flagellar stator from marine Vibrio

    Tatsuro Nishikino, Norihiro Takekawa, Jun-ichi Kishikawa, Mika Hirose, Seiji Kojima, Michio Homma, Takayuki Kato, Katsumi Imada

    Proceedings of the National Academy of Sciences Vol. 122 No. 1 2024/12/30 Research paper (scientific journal)

    Publisher: Proceedings of the National Academy of Sciences
  5. Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motor.

    Norihiro Takekawa, Tatsuro Nishikino, Jun-Ichi Kishikawa, Mika Hirose, Miki Kinoshita, Seiji Kojima, Tohru Minamino, Takayuki Uchihashi, Takayuki Kato, Katsumi Imada, Michio Homma

    mBio 2024/09/06 Research paper (scientific journal)

  6. Red fluorescent proteins engineered from green fluorescent proteins.

    Hiromi Imamura, Shiho Otsubo, Mizuho Nishida, Norihiro Takekawa, Katsumi Imada

    Proceedings of the National Academy of Sciences of the United States of America Vol. 120 No. 45 2023/11/07 Research paper (scientific journal)

  7. Structure of MotA, a flagellar stator protein, from hyperthermophile.

    Tatsuro Nishikino, Norihiro Takekawa, Duy Phuoc Tran, Jun-Ichi Kishikawa, Mika Hirose, Sakura Onoe, Seiji Kojima, Michio Homma, Akio Kitao, Takayuki Kato, Katsumi Imada

    Biochemical and biophysical research communications Vol. 631 p. 78-85 2022/11/26 Research paper (scientific journal)

  8. Formation of multiple flagella caused by a mutation of the flagellar rotor protein FliM in Vibrio alginolyticus.

    Michio Homma, Norihiro Takekawa, Kazushi Fujiwara, Yuxi Hao, Yasuhiro Onoue, Seiji Kojima

    Genes to cells : devoted to molecular & cellular mechanisms Vol. 27 No. 9 p. 568-578 2022/09 Research paper (scientific journal)

  9. Structural basis of ubiquitin recognition by a bacterial OTU deubiquitinase LotA

    Norihiro Takekawa, Tomoko Kubori, Tomoya Iwai, Hiroki Nagai, Katsumi Imada

    Journal of Bacteriology Vol. 204 No. 1 2022/01/18 Research paper (scientific journal)

    Publisher: American Society for Microbiology
  10. A slight bending of an α-helix in FliM creates a counterclockwise-locked structure of the flagellar motor in Vibrio.

    Norihiro Takekawa, Tatsuro Nishikino, Toshiki Yamashita, Kiyoshiro Hori, Yasuhiro Onoue, Kunio Ihara, Seiji Kojima, Michio Homma, Katsumi Imada

    Journal of biochemistry Vol. 170 No. 4 p. 531-538 2021/12/04 Research paper (scientific journal)

  11. ZomB is essential for chemotaxis of Vibrio alginolyticus by the rotational direction control of the polar flagellar motor.

    Norihiro Takekawa, Tatsuro Nishikino, Kiyoshiro Hori, Seiji Kojima, Katsumi Imada, Michio Homma

    Genes to cells Vol. 26 No. 11 p. 927-937 2021/11 Research paper (scientific journal)

  12. The FlhA linker mediates flagellar protein export switching during flagellar assembly

    Yumi Inoue, Miki Kinoshita, Mamoru Kida, Norihiro Takekawa, Keiichi Namba, Katsumi Imada, Tohru Minamino

    Communications Biology Vol. 4 No. 1 2021/05/31 Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC
  13. Two Distinct Conformations in 34 FliF Subunits Generate Three Different Symmetries within the Flagellar MS-Ring

    Norihiro Takekawa, Akihiro Kawamoto, Mayuko Sakuma, Takayuki Kato, Seiji Kojima, Miki Kinoshita, Tohru Minamino, Keiichi Namba, Michio Homma, Katsumi Imada

    mBio Vol. 12 No. 2 2021/03/02 Research paper (scientific journal)

    Publisher: American Society for Microbiology
  14. In situ structure of the Vibrio polar flagellum reveals distinct outer membrane complex and its specific interaction with the stator.

    Shiwei Zhu, Tatsuro Nishikino, Norihiro Takekawa, Hiroyuki Terashima, Seiji Kojima, Katsumi Imada, Michio Homma, Jun Liu

    Journal of Bacteriology Vol. 202 No. 4 2019/11 Research paper (scientific journal)

  15. Structure of Vibrio FliL, a New Stomatin-like Protein That Assists the Bacterial Flagellar Motor Function.

    Takekawa N, Isumi M, Terashima H, Zhu S, Nishino Y, Sakuma M, Kojima S, Homma M, Imada K

    mBio Vol. 10 No. 2 2019/03 Research paper (scientific journal)

  16. The role of conserved charged residues in the bidirectional rotation of the bacterial flagellar motor.

    Yasuhiro Onoue, Norihiro Takekawa, Tatsuro Nishikino, Seiji Kojima, Michio Homma

    MicrobiologyOpen Vol. 7 No. 4 2018/03

  17. Localization and domain characterization of the SflA regulator of flagellar formation in Vibrio alginolyticus

    Satoshi Inaba, Takehiko Nishigaki, Norihiro Takekawa, Seiji Kojima, Michio Homma

    GENES TO CELLS Vol. 22 No. 7 p. 619-627 2017/07 Research paper (scientific journal)

  18. Mutational analysis and overproduction effects of MotX, an essential component for motor function of Na+-driven polar flagella of Vibrio

    Norihiro Takekawa, Seiji Kojima, Michio Homma

    JOURNAL OF BIOCHEMISTRY Vol. 161 No. 2 p. 159-166 2017/02 Research paper (scientific journal)

  19. HubP, a Polar Landmark Protein, Regulates Flagellar Number by Assisting in the Proper Polar Localization of FlhG in Vibrio alginolyticus

    Norihiro Takekawa, Soojin Kwon, Noriko Nishioka, Seiji Kojima, Michio Homma

    JOURNAL OF BACTERIOLOGY Vol. 198 No. 22 p. 3091-3098 2016/11 Research paper (scientific journal)

  20. The tetrameric MotA complex as the core of the flagellar motor stator from hyperthermophilic bacterium

    Norihiro Takekawa, Naoya Terahara, Takayuki Kato, Mizuki Gohara, Kouta Mayanagi, Atsushi Hijikata, Yasuhiro Onoue, Seiji Kojima, Tsuyoshi Shirai, Keiichi Namba, Michio Homma

    SCIENTIFIC REPORTS Vol. 6 2016/08 Research paper (scientific journal)

  21. Serine suppresses the motor function of a periplasmic PomB mutation in the Vibrio flagella stator

    Tatsuro Nishikino, Shiwei Zhu, Norihiro Takekawa, Seiji Kojima, Yasuhiro Onoue, Michio Homma

    GENES TO CELLS Vol. 21 No. 5 p. 505-516 2016/05 Research paper (scientific journal)

  22. Sodium-driven energy conversion for flagellar rotation of the earliest divergent hyperthermophilic bacterium

    Norihiro Takekawa, Masayoshi Nishiyama, Tsuyoshi Kaneseki, Tamotsu Kanai, Haruyuki Atomi, Seiji Kojima, Michio Homma

    SCIENTIFIC REPORTS Vol. 5 2015/08 Research paper (scientific journal)

  23. Contribution of Many Charged Residues at the Stator-Rotor Interface of the Na+ -Driven Flagellar Motor to Torque Generation in Vibrio alginolyticus

    Norihiro Takekawa, Seiji Kojima, Michio Homma

    JOURNAL OF BACTERIOLOGY Vol. 196 No. 7 p. 1377-1385 2014/04 Research paper (scientific journal)

  24. 1P196 Effect of mutations in FliG and PomB on rotational direction of flagellar motor in Vibrio alginolyticus(12. Cell biology,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

    Nishikino Tatsuro, Onoue Yasuhiro, Takekawa Norihiro, Zhu Shiwei, Kojima Seiji, Homma Michio

    Seibutsu Butsuri Vol. 54 No. 1 2014

    Publisher: The Biophysical Society of Japan General Incorporated Association
  25. 2P178 The bidirectional role of conserved charged residues in rotor-stator interaction in a rotary motor of bacterial flagella(12. Cell biology,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

    Onoue Yasuhiro, Takekawa Norihiro, Nishikino Tatsuro, Kojima Seiji, Homma Michio

    Seibutsu Butsuri Vol. 54 No. 1 2014

    Publisher: The Biophysical Society of Japan General Incorporated Association
  26. 1P174 Attempt to reconstruct the stator complex of the bacterial Na^+-driven flagellar motor into Nanodisc(12. Cell biology,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

    Gohara Mizuki, Takekawa Norihiro, Miyanoiri Yohei, Kainosho Masatune, Kojima Seiji, Homma Michio

    Seibutsu Butsuri Vol. 54 No. 1 2014

    Publisher: The Biophysical Society of Japan General Incorporated Association
  27. Fluorescence imaging of GFP-fused periplasmic components of Na+-driven flagellar motor using Tat pathway in Vibrio alginolyticus

    Norihiro Takekawa, Seiji Kojima, Michio Homma

    JOURNAL OF BIOCHEMISTRY Vol. 153 No. 6 p. 547-553 2013/06 Research paper (scientific journal)

  28. Na+ conductivity of the Na+-driven flagellar motor complex composed of unplugged wild-type or mutant PomB with PomA

    Norihiro Takekawa, Takashi Terauchi, Yusuke V. Morimoto, Tohru Minamino, Chien-Jung Lo, Seiji Kojima, Michio Homma

    JOURNAL OF BIOCHEMISTRY Vol. 153 No. 5 p. 441-451 2013/05 Research paper (scientific journal)

  29. 3P196 Flagellar stator protein of Vibrio PomA alone could form multimeric complex(12. Cell biology,Poster)

    Gohara Mizuki, Takekawa Norihiro, Miyanoiri Yohei, Kainosho Masatune, Kojima Seiji, Homma Michio

    Seibutsu Butsuri Vol. 53 No. 1 2013

    Publisher: The Biophysical Society of Japan General Incorporated Association
  30. 3P200 Characterization of the stator proteins of flagellar motor from extreme thermophile Aquifex aeolicus(12. Cell biology,Poster)

    Takekawa Norihiro, Gohara Mizuki, Kojima Seiji, Homma Michio

    Seibutsu Butsuri Vol. 53 No. 1 2013

    Publisher: The Biophysical Society of Japan General Incorporated Association
  31. Characterization of PomA Mutants Defective in the Functional Assembly of the Na+-Driven Flagellar Motor in Vibrio alginolyticus

    Norihiro Takekawa, Na Li, Seiji Kojima, Michio Homma

    JOURNAL OF BACTERIOLOGY Vol. 194 No. 8 p. 1934-1939 2012/04 Research paper (scientific journal)

  32. 2I1534 Synergetic effects of the mutations of charged residues between the rotor and the stator in the Na^+-driven flagellar motor(Cell Biology II: Prokaryotes,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)

    Takekawa Norihiro, Kojima Seiji, Homma Michio

    Seibutsu Butsuri Vol. 52 2012

    Publisher: The Biophysical Society of Japan General Incorporated Association
  33. Mutations Targeting the C-Terminal Domain of FliG Can Disrupt Motor Assembly in the Na+-Driven Flagella of Vibrio alginolyticus

    Seiji Kojima, Natsumi Nonoyama, Norihiro Takekawa, Hajime Fukuoka, Michio Homma

    JOURNAL OF MOLECULAR BIOLOGY Vol. 414 No. 1 p. 62-74 2011/11 Research paper (scientific journal)

Misc. 3

  1. Structure and Energy-Conversion Mechanism of the Bacterial Na+-Driven Flagellar Motor

    Norihiro Takekawa, Katsumi Imada, Michio Homma

    Trends in Microbiology Vol. 28 No. 9 p. 719-731 2020/09 Article, review, commentary, editorial, etc. (scientific journal)

    Publisher: Elsevier BV
  2. イオン駆動力で動く生物モーターの構造とエネルギー変換機構

    竹川宜宏, 本間道夫

    生化学 Vol. 91 No. 4 p. 461-471 2019/08 Article, review, commentary, editorial, etc. (scientific journal)

  3. 細菌の祖先がもつ運動マシナリーを現代に蘇らせる

    西山雅祥, 金井保, 竹川宜宏

    生物工学会誌 Vol. 96 No. 4 p. 191-194 2018/07 Article, review, commentary, editorial, etc. (scientific journal)

Institutional Repository 2

Content Published in the University of Osaka Institutional Repository (OUKA)
  1. Sodium-Dependent Conformational Change in Flagellar Stator Protein MotS from Bacillus subtilis

    Takekawa Norihiro, Yamaguchi Ayaka, Nishiuchi Koki, Uehori Maria, Kinoshita Miki, Minamino Tohru, Imada Katsumi

    Biomolecules Vol. 15 No. 2 2025/02/18

  2. Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motor

    Takekawa Norihiro, Nishikino Tatsuro, Kishikawa Junichi, Hirose Mika, Kinoshita Miki, Kojima Seiji, Minamino Tohru, Uchihashi Takayuki, Kato Takayuki, Imada Katsumi, Homma Michio

    mBio Vol. 15 No. 10 2024/09/06