A case of SAPHO syndrome with the lesions limited to the skull.

Eri Oguro, Yasuhiro Kato, Hyota Takamatsu, Masashi Narazaki, Atsushi Kumanogoh

Rheumatology advances in practice　Vol. 4　No. 2　2020年　研究論文（学術雑誌）

Apoptosis-derived membrane vesicles drive the cGAS-STING pathway and enhance type I IFN production in systemic lupus erythematosus.

Yasuhiro Kato, JeongHoon Park, Hyota Takamatsu, Hachirou Konaka, Wataru Aoki, Syunsuke Aburaya, Mitsuyoshi Ueda, Masayuki Nishide, Shohei Koyama, Yoshitomo Hayama, Yuhei Kinehara, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

Annals of the rheumatic diseases　Vol. 77　No. 10　p. 1507-1515　2018年10月　研究論文（学術雑誌）

Peripheral Neuropathy in Systemic Sclerosis with Proximal Nerve Involvement: Diagnostic Challenges and Response to Corticosteroid Therapy

Takehiro Suzuki, Takahiro Kawasaki, Goichi Beck, Noyuri Takenaka, Kotaro Ogawa, Eri Itotagawa, Kazuki Matsukawa, Michiko Ohashi, Takeshi Kaneko, Eri Oguro-Igashira, Yumiko Mizuno, Mayuko Izumi, Kohei Tsujimoto, Yasutaka Okita, Takayoshi Morita, Akane Watanabe, Yasuhiro Kato, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

Modern Rheumatology Case Reports　2025年1月30日　研究論文（学術雑誌）

Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients

Shuhei Sakakibara, Yu-Chen Liu, Masakazu Ishikawa, Ryuya Edahiro, Yuya Shirai, Soichiro Haruna, Marwa Ali El Hussien, Zichang Xu, Songling Li, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Fuminori Sugihara, Yoko Naito, Daisuke Motooka, Chao-Yuan Tsai, Chikako Ono, Yoshiharu Matsuura, James B Wing, Hisatake Matsumoto, Hiroshi Ogura, Masato Okada, Atsushi Kumanogoh, Yukinari Okada, Daron M Standley, Hitoshi Kikutani, Daisuke Okuzaki

Life Science Alliance　Vol. 7　No. 12　p. e202402774-e202402774　2024年9月17日　研究論文（学術雑誌）

Hypoglossal nerve palsy in IgG4-related disease

T Kaneko, Y Okita, Y Kato, M Narazaki, A Kumanogoh

QJM: An International Journal of Medicine　2024年3月27日　研究論文（学術雑誌）

BNT162b2 mRNAワクチン連続接種による短期的な自然免疫記憶の形成

熊ノ郷 淳, 山口 勇太, 加藤 保宏

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 68回　p. 1001-1001　2024年3月

全身性強皮症におけるレイノー現象対策の薬剤費の調査結果

嶋 良仁, 渡邉 あかね, 水野 裕美子, 泉 真祐子, 辻本 考平, 糸田川 英里, 西出 真之, 加藤 保宏, 楢崎 雅司, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 68回　p. 750-750　2024年3月

Sema6D forward signaling impairs T cell activation and proliferation in head and neck cancer.

Takashi Hirai, Yujiro Naito, Shohei Koyama, Yoshimitsu Nakanishi, Kentaro Masuhiro, Mayuko Izumi, Tomoki Kuge, Maiko Naito, Yumiko Mizuno, Yuta Yamaguchi, Sujin Kang, Moto Yaga, Yu Futami, Satoshi Nojima, Masayuki Nishide, Takayoshi Morita, Yasuhiro Kato, Takeshi Tsuda, Norihiko Takemoto, Yumi Kinugasa-Katayama, Taiki Aoshi, Jordan Kelly Villa, Kazuo Yamashita, Tomohiro Enokida, Yuta Hoshi, Kazuto Matsuura, Makoto Tahara, Hyota Takamatsu, Yoshito Takeda, Hidenori Inohara, Atsushi Kumanogoh

JCI insight　Vol. 9　No. 3　2024年2月8日　研究論文（学術雑誌）

Paradoxical improvement of dyspnoea in relapsing polychondritis by glucocorticoid tapering

Kenji Funakoshi, Yasuhiro Kato, Masashi Narazaki, Atsushi Kumanogoh

BMJ Case Reports　Vol. 17　No. 1　p. e257861-e257861　2024年1月24日　研究論文（学術雑誌）

Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases

Yoshiaki Yasumizu, Daiki Takeuchi, Reo Morimoto, Yusuke Takeshima, Tatsusada Okuno, Makoto Kinoshita, Takayoshi Morita, Yasuhiro Kato, Min Wang, Daisuke Motooka, Daisuke Okuzaki, Yamami Nakamura, Norihisa Mikami, Masaya Arai, Xuan Zhang, Atsushi Kumanogoh, Hideki Mochizuki, Naganari Ohkura, Shimon Sakaguchi

Cell Genomics　p. 100473-100473　2024年1月　研究論文（学術雑誌）

【免疫記憶の形成と疾患制御】自然免疫記憶

山口 勇太, 加藤 保宏, 熊ノ郷 淳

臨床免疫・アレルギー科　Vol. 80　No. 6　p. 625-630　2023年12月

Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis.

Masayuki Nishide, Kei Nishimura, Hiroaki Matsushita, Ryuya Edahiro, Sachi Inukai, Hiroshi Shimagami, Shoji Kawada, Yasuhiro Kato, Takahiro Kawasaki, Kohei Tsujimoto, Hokuto Kamon, Ryusuke Omiya, Yukinori Okada, Kunihiro Hattori, Masashi Narazaki, Atsushi Kumanogoh

Nature communications　Vol. 14　No. 1　p. 5789-5789　2023年10月11日　研究論文（学術雑誌）

Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome.

Hachiro Konaka, Yasuhiro Kato, Toru Hirano, Kohei Tsujimoto, JeongHoon Park, Taro Koba, Wataru Aoki, Yusei Matsuzaki, Masayasu Taki, Shohei Koyama, Eri Itotagawa, Tatsunori Jo, Takehiro Hirayama, Taro Kawai, Ken J Ishii, Mitsuyoshi Ueda, Shigehiro Yamaguchi, Shizuo Akira, Takayoshi Morita, Yuichi Maeda, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Hyota Takamatsu, Atsushi Kumanogoh

The EMBO journal　Vol. 42　No. 20　2023年9月4日　研究論文（学術雑誌）

SARS-CoV-2 mRNAワクチンと自然免疫応答

山口 勇太, 加藤 保宏, 熊ノ郷 淳

臨床免疫・アレルギー科　Vol. 80　No. 1　p. 108-113　2023年7月

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity.

Ryuya Edahiro, Yuya Shirai, Yusuke Takeshima, Shuhei Sakakibara, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Yu-Chen Liu, Daisuke Motooka, Yoko Naito, Ayako Takuwa, Fuminori Sugihara, Kentaro Tanaka, James B Wing, Kyuto Sonehara, Yoshihiko Tomofuji, Ho Namkoong, Hiromu Tanaka, Ho Lee, Koichi Fukunaga, Haruhiko Hirata, Yoshito Takeda, Daisuke Okuzaki, Atsushi Kumanogoh, Yukinori Okada

Nature genetics　Vol. 55　No. 5　p. 753-767　2023年4月24日　研究論文（学術雑誌）

SLE 基礎研究 Vorinostatによるループスモデルマウスにおける治療効果

平山 健寛, 小中 八郎, 加藤 保宏, 高松 漂太, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 67回　p. 711-711　2023年3月

血清BAFF・IFN-I活性によるSLEの層別化とループス腎炎における糸球体産生BAFFの意義

糸田川 英里, 加藤 保宏, 高松 漂太, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 67回　p. 886-886　2023年3月

【COVID-19重症化・後遺症のメカニズム 免疫応答の個人差がみえてきた】I型IFN経路を中心とした自然免疫とCOVID-19

網屋 沙織, 加藤 保宏, 熊ノ郷 淳

実験医学　Vol. 41　No. 4　p. 527-532　2023年3月

A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients.

Jonas Nørskov Søndergaard, Janyerkye Tulyeu, Ryuya Edahiro, Yuya Shirai, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Daisuke Okuzaki, Shimon Sakaguchi, Atsushi Kumanogoh, Yukinori Okada, James Badger Wing

Proceedings of the National Academy of Sciences of the United States of America　Vol. 120　No. 4　2023年1月24日　研究論文（学術雑誌）

Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19.

Takahiro Kawasaki, Yoshito Takeda, Ryuya Edahiro, Yuya Shirai, Mari Nogami-Itoh, Takanori Matsuki, Hiroshi Kida, Takatoshi Enomoto, Reina Hara, Yoshimi Noda, Yuichi Adachi, Takayuki Niitsu, Saori Amiya, Yuta Yamaguchi, Teruaki Murakami, Yasuhiro Kato, Takayoshi Morita, Hanako Yoshimura, Makoto Yamamoto, Daisuke Nakatsubo, Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Jun Adachi, Yukinori Okada, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 42　No. 1　p. 53-53　2022年11月30日　研究論文（学術雑誌）

SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis.

Eri Itotagawa, Yoshihiko Tomofuji, Yasuhiro Kato, Hachiro Konaka, Kohei Tsujimoto, JeongHoon Park, Daiki Nagira, Takehiro Hirayama, Tatsunori Jo, Toru Hirano, Takayoshi Morita, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Yukinori Okada, Hyota Takamatsu, Atsushi Kumanogoh

Rheumatology (Oxford, England)　Vol. 62　No. 5　p. 1988-1997　2022年9月12日　研究論文（学術雑誌）

The proliferative activity levels of each immune cell population evaluated by mass cytometry are linked to the clinical phenotypes of systemic lupus erythematosus.

Kajihara Akiko, Takayoshi Morita, Yasuhiro Kato, Hachiro Konaka, Teruaki Murakami, Yuta Yamaguchi, Shohei Koyama, Hyota Takamatsu, Masayuki Nishide, Yuichi Maeda, Akane Watanabe, Sumiyuki Nishida, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

International immunology　Vol. 35　No. 1　p. 27-41　2022年8月23日　研究論文（学術雑誌）

The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force.

Qingbo S Wang, Ryuya Edahiro, Ho Namkoong, Takanori Hasegawa, Yuya Shirai, Kyuto Sonehara, Hiromu Tanaka, Ho Lee, Ryunosuke Saiki, Takayoshi Hyugaji, Eigo Shimizu, Kotoe Katayama, Masahiro Kanai, Tatsuhiko Naito, Noah Sasa, Kenichi Yamamoto, Yasuhiro Kato, Takayoshi Morita, Kazuhisa Takahashi, Norihiro Harada, Toshio Naito, Makoto Hiki, Yasushi Matsushita, Haruhi Takagi, Masako Ichikawa, Ai Nakamura, Sonoko Harada, Yuuki Sandhu, Hiroki Kabata, Katsunori Masaki, Hirofumi Kamata, Shinnosuke Ikemura, Shotaro Chubachi, Satoshi Okamori, Hideki Terai, Atsuho Morita, Takanori Asakura, Junichi Sasaki, Hiroshi Morisaki, Yoshifumi Uwamino, Kosaku Nanki, Sho Uchida, Shunsuke Uno, Tomoyasu Nishimura, Takashri Ishiguro, Taisuke Isono, Shun Shibata, Yuma Matsui, Chiaki Hosoda, Kenji Takano, Takashi Nishida, Yoichi Kobayashi, Yotaro Takaku, Noboru Takayanagi, Soichiro Ueda, Ai Tada, Masayoshi Miyawaki, Masaomi Yamamoto, Eriko Yoshida, Reina Hayashi, Tomoki Nagasaka, Sawako Arai, Yutaro Kaneko, Kana Sasaki, Etsuko Tagaya, Masatoshi Kawana, Ken Arimura, Kunihiko Takahashi, Tatsuhiko Anzai, Satoshi Ito, Akifumi Endo, Yuji Uchimura, Yasunari Miyazaki, Takayuki Honda, Tomoya Tateishi, Shuji Tohda, Naoya Ichimura, Kazunari Sonobe, Chihiro Tani Sassa, Jun Nakajima, Yasushi Nakano, Yukiko Nakajima, Ryusuke Anan, Ryosuke Arai, Yuko Kurihara, Yuko Harada, Kazumi Nishio, Tetsuya Ueda, Masanori Azuma, Ryuichi Saito, Toshikatsu Sado, Yoshimune Miyazaki, Ryuichi Sato, Yuki Haruta, Tadao Nagasaki, Yoshinori Yasui, Yoshinori Hasegawa, Yoshikazu Mutoh, Tomoki Kimura, Tomonori Sato, Reoto Takei, Satoshi Hagimoto, Yoichiro Noguchi, Yasuhiko Yamano, Hajime Sasano, Sho Ota, Yasushi Nakamori, Kazuhisa Yoshiya, Fukuki Saito, Tomoyuki Yoshihara, Daiki Wada, Hiromu Iwamura, Syuji Kanayama, Shuhei Maruyama, Takashi Yoshiyama, Ken Ohta, Hiroyuki Kokuto, Hideo Ogata, Yoshiaki Tanaka, Kenichi Arakawa, Masafumi Shimoda, Takeshi Osawa, Hiroki Tateno, Isano Hase, Shuichi Yoshida, Shoji Suzuki, Miki Kawada, Hirohisa Horinouchi, Fumitake Saito, Keiko Mitamura, Masao Hagihara, Junichi Ochi, Tomoyuki Uchida, Rie Baba, Daisuke Arai, Takayuki Ogura, Hidenori Takahashi, Shigehiro Hagiwara, Genta Nagao, Shunichiro Konishi, Ichiro Nakachi, Koji Murakami, Mitsuhiro Yamada, Hisatoshi Sugiura, Hirohito Sano, Shuichiro Matsumoto, Nozomu Kimura, Yoshinao Ono, Hiroaki Baba, Yusuke Suzuki, Sohei Nakayama, Keita Masuzawa, Shinichi Namba, Takayuki Shiroyama, Yoshimi Noda, Takayuki Niitsu, Yuichi Adachi, Takatoshi Enomoto, Saori Amiya, Reina Hara, Yuta Yamaguchi, Teruaki Murakami, Tomoki Kuge, Kinnosuke Matsumoto, Yuji Yamamoto, Makoto Yamamoto, Midori Yoneda, Kazunori Tomono, Kazuto Kato, Haruhiko Hirata, Yoshito Takeda, Hidefumi Koh, Tadashi Manabe, Yohei Funatsu, Fumimaro Ito, Takahiro Fukui, Keisuke Shinozuka, Sumiko Kohashi, Masatoshi Miyazaki, Tomohisa Shoko, Mitsuaki Kojima, Tomohiro Adachi, Motonao Ishikawa, Kenichiro Takahashi, Takashi Inoue, Toshiyuki Hirano, Keigo Kobayashi, Hatsuyo Takaoka, Kazuyoshi Watanabe, Naoki Miyazawa, Yasuhiro Kimura, Reiko Sado, Hideyasu Sugimoto, Akane Kamiya, Naota Kuwahara, Akiko Fujiwara, Tomohiro Matsunaga, Yoko Sato, Takenori Okada, Yoshihiro Hirai, Hidetoshi Kawashima, Atsuya Narita, Kazuki Niwa, Yoshiyuki Sekikawa, Koichi Nishi, Masaru Nishitsuji, Mayuko Tani, Junya Suzuki, Hiroki Nakatsumi, Takashi Ogura, Hideya Kitamura, Eri Hagiwara, Kota Murohashi, Hiroko Okabayashi, Takao Mochimaru, Shigenari Nukaga, Ryosuke Satomi, Yoshitaka Oyamada, Nobuaki Mori, Tomoya Baba, Yasutaka Fukui, Mitsuru Odate, Shuko Mashimo, Yasushi Makino, Kazuma Yagi, Mizuha Hashiguchi, Junko Kagyo, Tetsuya Shiomi, Satoshi Fuke, Hiroshi Saito, Tomoya Tsuchida, Shigeki Fujitani, Mumon Takita, Daiki Morikawa, Toru Yoshida, Takehiro Izumo, Minoru Inomata, Naoyuki Kuse, Nobuyasu Awano, Mari Tone, Akihiro Ito, Yoshihiko Nakamura, Kota Hoshino, Junichi Maruyama, Hiroyasu Ishikura, Tohru Takata, Toshio Odani, Masaru Amishima, Takeshi Hattori, Yasuo Shichinohe, Takashi Kagaya, Toshiyuki Kita, Kazuhide Ohta, Satoru Sakagami, Kiyoshi Koshida, Kentaro Hayashi, Tetsuo Shimizu, Yutaka Kozu, Hisato Hiranuma, Yasuhiro Gon, Namiki Izumi, Kaoru Nagata, Ken Ueda, Reiko Taki, Satoko Hanada, Kodai Kawamura, Kazuya Ichikado, Kenta Nishiyama, Hiroyuki Muranaka, Kazunori Nakamura, Naozumi Hashimoto, Keiko Wakahara, Sakamoto Koji, Norihito Omote, Akira Ando, Nobuhiro Kodama, Yasunari Kaneyama, Shunsuke Maeda, Takashige Kuraki, Takemasa Matsumoto, Koutaro Yokote, Taka-Aki Nakada, Ryuzo Abe, Taku Oshima, Tadanaga Shimada, Masahiro Harada, Takeshi Takahashi, Hiroshi Ono, Toshihiro Sakurai, Takayuki Shibusawa, Yoshifumi Kimizuka, Akihiko Kawana, Tomoya Sano, Chie Watanabe, Ryohei Suematsu, Hisako Sageshima, Ayumi Yoshifuji, Kazuto Ito, Saeko Takahashi, Kota Ishioka, Morio Nakamura, Makoto Masuda, Aya Wakabayashi, Hiroki Watanabe, Suguru Ueda, Masanori Nishikawa, Yusuke Chihara, Mayumi Takeuchi, Keisuke Onoi, Jun Shinozuka, Atsushi Sueyoshi, Yoji Nagasaki, Masaki Okamoto, Sayoko Ishihara, Masatoshi Shimo, Yoshihisa Tokunaga, Yu Kusaka, Takehiko Ohba, Susumu Isogai, Aki Ogawa, Takuya Inoue, Satoru Fukuyama, Yoshihiro Eriguchi, Akiko Yonekawa, Keiko Kan-O, Koichiro Matsumoto, Kensuke Kanaoka, Shoichi Ihara, Kiyoshi Komuta, Yoshiaki Inoue, Shigeru Chiba, Kunihiro Yamagata, Yuji Hiramatsu, Hirayasu Kai, Koichiro Asano, Tsuyoshi Oguma, Yoko Ito, Satoru Hashimoto, Masaki Yamasaki, Yu Kasamatsu, Yuko Komase, Naoya Hida, Takahiro Tsuburai, Baku Oyama, Minoru Takada, Hidenori Kanda, Yuichiro Kitagawa, Tetsuya Fukuta, Takahito Miyake, Shozo Yoshida, Shinji Ogura, Shinji Abe, Yuta Kono, Yuki Togashi, Hiroyuki Takoi, Ryota Kikuchi, Shinichi Ogawa, Tomouki Ogata, Shoichiro Ishihara, Arihiko Kanehiro, Shinji Ozaki, Yasuko Fuchimoto, Sae Wada, Nobukazu Fujimoto, Kei Nishiyama, Mariko Terashima, Satoru Beppu, Kosuke Yoshida, Osamu Narumoto, Hideaki Nagai, Nobuharu Ooshima, Mitsuru Motegi, Akira Umeda, Kazuya Miyagawa, Hisato Shimada, Mayu Endo, Yoshiyuki Ohira, Masafumi Watanabe, Sumito Inoue, Akira Igarashi, Masamichi Sato, Hironori Sagara, Akihiko Tanaka, Shin Ohta, Tomoyuki Kimura, Yoko Shibata, Yoshinori Tanino, Takefumi Nikaido, Hiroyuki Minemura, Yuki Sato, Yuichiro Yamada, Takuya Hashino, Masato Shinoki, Hajime Iwagoe, Hiroshi Takahashi, Kazuhiko Fujii, Hiroto Kishi, Masayuki Kanai, Tomonori Imamura, Tatsuya Yamashita, Masakiyo Yatomi, Toshitaka Maeno, Shinichi Hayashi, Mai Takahashi, Mizuki Kuramochi, Isamu Kamimaki, Yoshiteru Tominaga, Tomoo Ishii, Mitsuyoshi Utsugi, Akihiro Ono, Toru Tanaka, Takeru Kashiwada, Kazue Fujita, Yoshinobu Saito, Masahiro Seike, Hiroko Watanabe, Hiroto Matsuse, Norio Kodaka, Chihiro Nakano, Takeshi Oshio, Takatomo Hirouchi, Shohei Makino, Moritoki Egi, Yosuke Omae, Yasuhito Nannya, Takafumi Ueno, Tomomi Takano, Kazuhiko Katayama, Masumi Ai, Atsushi Kumanogoh, Toshiro Sato, Naoki Hasegawa, Katsushi Tokunaga, Makoto Ishii, Ryuji Koike, Yuko Kitagawa, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada

Nature communications　Vol. 13　No. 1　p. 4830-4830　2022年8月22日　研究論文（学術雑誌）

発作性夜間ヘモグロビン尿症に対する新型コロナウィルスワクチンの有効性と安全性の検討

植田 康敬, 高森 弘之, 加藤 保宏, 森田 貴義, 堤 一仁, 一井 倫子, 西村 純一, 熊ノ郷 淳, 保仙 直毅

補体　Vol. 59　No. 1　p. 57-58　2022年8月

発作性夜間ヘモグロビン尿症に対する新型コロナウィルスワクチンの有効性と安全性の検討

植田康敬, 高森弘之, 加藤保宏, 森田貴義, 堤一仁, 一井倫子, 西村純一, 熊ノ郷淳, 保仙直毅

補体　Vol. 59　No. 1　p. 57-58　2022年8月　研究論文（学術雑誌）

多発性骨髄腫およびMGUS患者に対するCovid-19ワクチンの有用性に関する単施設前向き研究(A single center prospective study about efficacy of the Covid-19 vaccines in patients of multiple myeloma and MGUS)

堤 一仁, 一井 倫子, 加藤 保宏, 森田 貴義, 山口 勇太, 村上 輝明, 熊ノ郷 淳, 保仙 直毅

International Journal of Myeloma　Vol. 12　No. 3　p. 142-142　2022年5月

多発性筋炎・皮膚筋炎の肺病変 血栓性微小血管症を併発し致死的転帰となった筋無症候性皮膚筋炎の一例

川田 翔司, 前田 悠一, 岡本 雅志, 島上 洋, 多田 友美, 中坪 大亮, 沖田 康孝, 川崎 貴裕, 森田 貴義, 藤本 潤, 加藤 保宏, 渡邉 あかね, 高松 漂太, 嶋 良仁, 楢崎 雅司, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 66回　p. 409-409　2022年3月

その他の(多彩な)膠原病-薬剤関連膠原病様症状 胸膜炎と血清IFN-βの関連が示唆されるmRNAワクチン接種後発症の多関節炎2症例の比較

島上 洋, 岡本 雅志, 多田 友美, 川田 翔司, 中坪 大亮, 沖田 康孝, 川崎 貴裕, 森田 貴義, 藤本 潤, 加藤 保宏, 西出 真之, 前田 悠一, 渡邉 あかね, 高松 漂太, 嶋 良仁, 楢崎 雅司, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 66回　p. 387-387　2022年3月

ANCA関連血管炎:コホート研究・ケースシリーズ ANCA関連血管炎(AAV)に伴う肥厚性硬膜炎患者(HPM)の臨床的特徴の検討

藤本 潤, 川崎 貴裕, 沖田 康孝, 森田 貴義, 西出 真之, 前田 悠一, 加藤 保宏, 渡邉 あかね, 高松 漂太, 嶋 良仁, 楢崎 雅司, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 66回　p. 414-414　2022年3月

喉頭截開術を回避し、甲状軟骨生検にて診断しえた再発性多発軟骨炎の一例

中坪 大亮, 前田 悠一, 岡本 雅志, 島上 洋, 多田 友美, 川田 翔司, 沖田 康孝, 川崎 貴裕, 森田 貴義, 藤本 潤, 加藤 保宏, 西出 真之, 渡邉 あかね, 高松 漂太, 嶋 良仁, 楢崎 雅司, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 66回　p. 713-713　2022年3月

Good症候群による多関節炎・心膜炎に対してミノサイクリンが著効した一例

岡本 雅志, 島上 洋, 多田 友美, 中坪 大亮, 川田 翔司, 沖田 康孝, 森田 貴義, 川崎 貴裕, 藤本 潤, 前田 悠一, 西出 真之, 加藤 保宏, 渡邉 あかね, 高松 漂太, 嶋 良仁, 楢崎 雅司, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 66回　p. 716-716　2022年3月

Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.

Xiuyuan Lu, Yuki Hosono, Masamichi Nagae, Shigenari Ishizuka, Eri Ishikawa, Daisuke Motooka, Yuki Ozaki, Nicolas Sax, Yuichi Maeda, Yasuhiro Kato, Takayoshi Morita, Ryo Shinnakasu, Takeshi Inoue, Taishi Onodera, Takayuki Matsumura, Masaharu Shinkai, Takashi Sato, Shota Nakamura, Shunsuke Mori, Teru Kanda, Emi E Nakayama, Tatsuo Shioda, Tomohiro Kurosaki, Kiyoshi Takeda, Atsushi Kumanogoh, Hisashi Arase, Hironori Nakagami, Kazuo Yamashita, Yoshimasa Takahashi, Sho Yamasaki

The Journal of experimental medicine　Vol. 218　No. 12　2021年12月6日　研究論文（学術雑誌）

Rapid attenuation of anti-SARS-CoV-2 antibodies in patients with musculoskeletal diseases in whom intensive immunosuppressive therapies were reinitiated after COVID-19: comment on the article by Curtis et al.

Masashi Okamoto, Shoji Kawada, Hiroshi Shimagami, Naoko Fujii, Kazuki Matsukawa, Nachi Ishikawa, Keisuke Kawamoto, Shinji Higa, Yutaka Ishida, Atsushi Ogata, Yuta Yamaguchi, Takayoshi Morita, Yasuhiro Kato, Atsushi Kumanogoh

Arthritis & rheumatology (Hoboken, N.J.)　Vol. 74　No. 4　p. 726-728　2021年10月25日

The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II.

Takeshi Nakatani, Kohei Tsujimoto, JeongHoon Park, Tatsunori Jo, Tetsuya Kimura, Yoshitomo Hayama, Hachiro Konaka, Takayoshi Morita, Yasuhiro Kato, Masayuki Nishide, Shyohei Koyama, Shigeyuki Nada, Masato Okada, Hyota Takamatsu, Atsushi Kumanogoh

Nature communications　Vol. 12　No. 1　p. 3333-3333　2021年6月7日　研究論文（学術雑誌）

Radioligand Assay-Based Detection of Antibodies against SARS-CoV-2 in Hospital Workers Treating Patients with Severe COVID-19 in Japan.

Hidenori Matsunaga, Akiko Makino, Yasuhiro Kato, Teruaki Murakami, Yuta Yamaguchi, Atsushi Kumanogoh, Yuichiro Oba, Satoshi Fujimi, Tomoyuki Honda, Keizo Tomonaga

Viruses　Vol. 13　No. 2　2021年2月23日　研究論文（学術雑誌）

Predicting recurrence of respiratory failure in critically ill patients with COVID-19: A preliminary study.

Yuichi Adachi, Takayuki Shiroyama, Yuta Yamaguchi, Teruaki Murakami, Haruhiko Hirata, Saori Amiya, Takayuki Niitsu, Yoshimi Noda, Reina Hara, Takatoshi Enomoto, Takayoshi Morita, Yasuhiro Kato, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

The Journal of infection　Vol. 82　No. 5　2021年1月24日　研究論文（学術雑誌）

Withdrawal of Glucocorticoid Therapy is Difficult in Women with Polymyalgia Rheumatica: An Observational Study.

Dai Aoki, Nobuyuki Kajiwara, Keiko Irishio, Yasuhiro Kato, Shinya Suezaki, Misaki Kageyama, Masahiro Misago, Daisuke Tamai, Shinichiro Nakao, Takato Ueoka, Mototoshi Ito, Shinichiro Murakami

International journal of general medicine　Vol. 14　p. 6417-6422　2021年　研究論文（学術雑誌）

Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis.

Takeshi Tsuda, Masayuki Nishide, Yohei Maeda, Yoshitomo Hayama, Shohei Koyama, Satoshi Nojima, Hyota Takamatsu, Daisuke Okuzaki, Takayoshi Morita, Takeshi Nakatani, Yasuhiro Kato, Yoshimitsu Nakanishi, Yu Futami, Yasuhiko Suga, Yujiro Naito, Hachiro Konaka, Shingo Satoh, Maiko Naito, Mayuko Izumi, Sho Obata, Ayaka Nakatani, Takashi Shikina, Kazuya Takeda, Masaki Hayama, Hidenori Inohara, Atsushi Kumanogoh

The Journal of allergy and clinical immunology　Vol. 145　No. 3　p. 843-854　2020年3月　研究論文（学術雑誌）

Subcutaneous tocilizumab: recent advances for the treatment of rheumatoid arthritis.

Atsushi Ogata, Yasuhiro Kato, Shinji Higa, Keiji Maeda

Expert opinion on drug delivery　Vol. 16　No. 6　p. 639-648　2019年6月　研究論文（学術雑誌）

SEMA4A promotes eosinophil survival and contributes to eosinophil-mediated allergic diseases.

Yohei Maeda, Takeshi Tsuda, Yoshito Takeda, Shohei Koyama, Yoshitomo Hayama, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Hyota Takamatsu, Sujin Kang, Masayuki Nishide, Keiko Morimoto, Takashi Hosokawa, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Kazuya Takeda, Masaki Hayama, Sho Obata, Hitoshi Akazawa, Takashi Shikina, Hidenori Inohara, Atsushi Kumanogoh

Allergology international : official journal of the Japanese Society of Allergology　Vol. 68　No. 2　p. 274-276　2019年4月

IL-6 inhibitor for the treatment of rheumatoid arthritis: A comprehensive review.

Atsushi Ogata, Yasuhiro Kato, Shinji Higa, Kazuyuki Yoshizaki

Modern rheumatology　Vol. 29　No. 2　p. 258-267　2019年3月　研究論文（学術雑誌）

Eosinophil-derived neurotoxin enhances airway remodeling in eosinophilic chronic rhinosinusitis and correlates with disease severity.

Takeshi Tsuda, Yohei Maeda, Masayuki Nishide, Shohei Koyama, Yoshitomo Hayama, Satoshi Nojima, Hyota Takamatsu, Daisuke Okuzaki, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Sho Obata, Hitoshi Akazawa, Takashi Shikina, Kazuya Takeda, Masaki Hayama, Hidenori Inohara, Atsushi Kumanogoh

International immunology　Vol. 31　No. 1　p. 33-40　2019年2月6日　研究論文（学術雑誌）

Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells.

Yuhei Kinehara, Izumi Nagatomo, Shohei Koyama, Daisuke Ito, Satoshi Nojima, Ryota Kurebayashi, Yoshimitsu Nakanishi, Yasuhiko Suga, Yu Nishijima-Futami, Akio Osa, Takeshi Nakatani, Yasuhiro Kato, Masayuki Nishide, Yoshitomo Hayama, Masayoshi Higashiguchi, Osamu Morimura, Kotaro Miyake, Sujin Kang, Toshiyuki Minami, Haruhiko Hirata, Kota Iwahori, Takayuki Takimoto, Hyota Takamatsu, Yoshito Takeda, Naoki Hosen, Shigenori Hoshino, Yasushi Shintani, Meinoshin Okumura, Toru Kumagai, Kazumi Nishino, Fumio Imamura, Shin-Ichi Nakatsuka, Takashi Kijima, Hiroshi Kida, Atsushi Kumanogoh

JCI insight　Vol. 3　No. 24　2018年12月20日　研究論文（学術雑誌）

Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.

Yoshitomo Hayama, Tetsuya Kimura, Yoshito Takeda, Shigeyuki Nada, Shohei Koyama, Hyota Takamatsu, Sujin Kang, Daisuke Ito, Yohei Maeda, Masayuki Nishide, Satoshi Nojima, Hana Sarashina-Kida, Takashi Hosokawa, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Yoshimitsu Nakanishi, Takeshi Tsuda, Taro Koba, Masato Okada, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 200　No. 11　p. 3790-3800　2018年6月1日　研究論文（学術雑誌）

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

Sujin Kang, Yoshimitsu Nakanishi, Yoshiyuki Kioi, Daisuke Okuzaki, Tetsuya Kimura, Hyota Takamatsu, Shohei Koyama, Satoshi Nojima, Masayuki Nishide, Yoshitomo Hayama, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Tomomi Shimogori, Junichi Takagi, Toshihiko Toyofuku, Atsushi Kumanogoh

Nature immunology　Vol. 19　No. 6　p. 561-570　2018年6月　研究論文（学術雑誌）

Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.

Takashi Hosokawa, Tetsuya Kimura, Shigeyuki Nada, Tatsusada Okuno, Daisuke Ito, Sujin Kang, Satoshi Nojima, Kazuya Yamashita, Takeshi Nakatani, Yoshitomo Hayama, Yasuhiro Kato, Yuhei Kinehara, Masayuki Nishide, Norihisa Mikami, Syohei Koyama, Hyota Takamatsu, Daisuke Okuzaki, Naganari Ohkura, Shimon Sakaguchi, Masato Okada, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 199　No. 6　p. 2008-2019　2017年9月15日　研究論文（学術雑誌）

Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.

Masayuki Nishide, Satoshi Nojima, Daisuke Ito, Hyota Takamatsu, Shohei Koyama, Sujin Kang, Tetsuya Kimura, Keiko Morimoto, Takashi Hosokawa, Yoshitomo Hayama, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Yoshimitsu Nakanishi, Takeshi Tsuda, Jeong Hoon Park, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Eiichi Morii, Atsushi Kumanogoh

Annals of the rheumatic diseases　Vol. 76　No. 8　p. 1440-1448　2017年8月　研究論文（学術雑誌）

Classification of idiopathic interstitial pneumonias using anti-myxovirus resistance-protein 1 autoantibody.

Yoshimasa Hamano, Hiroshi Kida, Shoichi Ihara, Akihiro Murakami, Masahiro Yanagawa, Ken Ueda, Osamu Honda, Lokesh P Tripathi, Toru Arai, Masaki Hirose, Toshimitsu Hamasaki, Yukihiro Yano, Tetsuya Kimura, Yasuhiro Kato, Hyota Takamatsu, Tomoyuki Otsuka, Toshiyuki Minami, Haruhiko Hirata, Koji Inoue, Izumi Nagatomo, Yoshito Takeda, Masahide Mori, Hiroyoshi Nishikawa, Kenji Mizuguchi, Takashi Kijima, Masanori Kitaichi, Noriyuki Tomiyama, Yoshikazu Inoue, Atsushi Kumanogoh

Scientific reports　Vol. 7　p. 43201-43201　2017年2月23日　研究論文（学術雑誌）

LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.

Keiko Morimoto, Yoshihiro Baba, Hisaaki Shinohara, Sujin Kang, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Yuji Yoshida, Yohei Maeda, Hana Sarashina-Kida, Masayuki Nishide, Takashi Hosokawa, Yasuhiro Kato, Yoshitomo Hayama, Yuhei Kinehara, Tatsusada Okuno, Hyota Takamatsu, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Tomohiro Kurosaki, Toshihiko Toyofuku, Atsushi Kumanogoh

Scientific reports　Vol. 6　p. 25738-25738　2016年5月11日　研究論文（学術雑誌）

Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2

Ohno, S., Ikeda, J.-I., Naito, Y., Okuzaki, D., Sasakura, T., Fukushima, K., Nishikawa, Y., Ota, K., Kato, Y., Wang, M., Torigata, K., Kasama, T., Uchihashi, T., Miura, D., Yabuta, N., Morii, E., Nojima, H.

Scientific reports　Vol. 6　No. 1　p. 39091-39091　2016年　研究論文（学術雑誌）

Optimization of Treatment Intervals of Tocilizumab and Golimumab By Measuring Serum Trough Levels in Rheumatoid Arthritis Patients

Yoshinobu Matsuura, Masashi Narazaki, Masayuki Nishide, Yasuhiro Kato, Hideki Yorifuji, Toru Hirano, Yoshihito Shima, Toshio Tanaka, Atsushi Ogata, Atsushi Kumanogoh

ARTHRITIS & RHEUMATOLOGY　Vol. 67　p. 815-816　2015年10月　研究論文（その他学術会議資料等）

局在診断に苦慮した原発性副甲状腺機能亢進症の1例

石橋 千咲, 平井 孝一, 奥野 陽亮, 北村 哲宏, 坂本 扶美枝, 加藤 保宏, 下田 雅史, 安田 哲行, 大月 道夫, 金藤 秀明, 今川 彰久, 船橋 徹, 野口 眞三郎, 下村 伊一郎

日本内分泌学会雑誌　Vol. 89　No. 3　p. 978-978　2013年12月