EN

基本情報

研究

社会活動

その他の活動

岡田 随象

Okada Yukinori

医学系研究科 医学専攻,教授

keyword 遺伝統計学,機械学習,バイオインフォマティクス,ゲノム免疫学,オミクス解析

学歴

  • 2007年04月 ~ 2011年03月,東京大学,大学院医学系研究科,内科学専攻 博士課程
  • 2001年04月 ~ 2005年03月,東京大学,医学部,医学科
  • 1999年04月 ~ 2001年03月,東京大学,教養学部,理科Ⅲ類

経歴

  • 2017年04月 ~ 継続中,大阪大学 免疫学フロンティア研究センター(IFReC),免役統計学,教授(兼任)
  • 2016年04月 ~ 継続中,大阪大学,大学院医学系研究科,教授
  • 2013年11月 ~ 2016年03月,東京医科歯科大学,テニュアトラック講師
  • 2012年04月 ~ 2013年11月,日本学術振興会,海外特別研究員
  • 2012年01月 ~ 2013年11月,Broad Institute,Postdoctoral Fellow
  • 2012年01月 ~ 2013年11月,Harvard Medical School,Brigham & Women's Hospital,Research Fellow
  • 2010年04月 ~ 2012年03月,日本学術振興会,特別研究員(DC2・PD)
  • 2005年04月 ~ 2007年03月,東京大学医学部附属病院,初期研修プログラム,初期研修医

研究内容・専門分野

  • ライフサイエンス,システムゲノム科学,バイオインフォマティクス
  • ライフサイエンス,医化学,集団遺伝学
  • ライフサイエンス,ゲノム生物学,遺伝統計学

論文

  • Genome-wide association studies,Uffelmann E,Huang QQ,Munung NS,de Vries J,Okada Y,Martin AR,Martin HC,Lappalainen T,PosthumaD,Nature Reviews Methods Primers,Springer Science and Business Media LLC,Vol. 1,No. 1,2021年12月,研究論文(学術雑誌)
  • Statistical genetics and polygenic risk score for precision medicine,Konuma T,Okada Y,Inflammation and Regeneration,Springer Science and Business Media LLC,Vol. 41,No. 1,2021年12月,研究論文(学術雑誌)
  • Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes,Hosoe J,Suzuki K,Miya F,Kato T,Tsunoda T,Okada Y,Horikoshi M,Shojima N,Yamauchi T,Kadowaki T,Human Genome Variation,Springer Science and Business Media LLC,Vol. 8,No. 1,2021年12月,研究論文(学術雑誌)
  • Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs,Wang QS,Kelley DR,Ulirsch J,Kanai M,Sadhuka S,Cui R,Albors C,Cheng N,Okada Y,Biobank Japan,Project,Aguet F,Ardlie KG,MacArthur DG,Finucane HK,Nature Communications,Springer Science and Business Media LLC,Vol. 12,No. 1,2021年12月,研究論文(学術雑誌)
  • Population-specific causal disease effect sizes in functionally important regions impacted by selection,Shi H†,Gazal S,Kanai M,Koch EM,Schoech AP,Siewert KM,Kim SS,Luo Y,Amariuta T,Huang H,Okada Y,Raychaudhuri S,Sunyaev SR,Price AL,Nature Communications,Springer Science and Business Media LLC,Vol. 12,No. 1,2021年12月,研究論文(学術雑誌)
  • Genomics-driven drug discovery based on disease-susceptibility genes,Sonehara K,Okada Y,Inflammation and Regeneration,Springer Science and Business Media LLC,Vol. 41,No. 1,p. ---,2021年12月,研究論文(学術雑誌)
  • A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.,Yang Luo,Masahiro Kanai,Wanson Choi,Xinyi Li,Saori Sakaue,Kenichi Yamamoto,Kotaro Ogawa,Maria Gutierrez-Arcelus,Peter K Gregersen,Philip E Stuart,James T Elder,Lukas Forer,Sebastian Schönherr,Christian Fuchsberger,Albert V Smith,Jacques Fellay,Mary Carrington,David W Haas,Xiuqing Guo,Nicholette D Palmer,Yii-Der Ida Chen,Jerome I Rotter,Kent D Taylor,Stephen S Rich,Adolfo Correa,James G Wilson,Sekar Kathiresan,Michael H Cho,Andres Metspalu,Tonu Esko,Yukinori Okada,Buhm Han,Paul J McLaren,Soumya Raychaudhuri,Nature genetics,Vol. 53,No. 10,p. 1504-1516,2021年10月,研究論文(学術雑誌)
  • A cross-population atlas of genetic associations for 220 human phenotypes,Saori Sakaue,Masahiro Kanai,Yosuke Tanigawa,Juha Karjalainen,Mitja Kurki,Seizo Koshiba,Akira Narita,Takahiro Konuma,Kenichi Yamamoto,Masato Akiyama,Kazuyoshi Ishigaki,Akari Suzuki,Ken Suzuki,Wataru Obara,Ken Yamaji,Kazuhisa Takahashi,Satoshi Asai,Yasuo Takahashi,Takao Suzuki,Nobuaki Shinozaki,Hiroki Yamaguchi,Shiro Minami,Shigeo Murayama,Kozo Yoshimori,Satoshi Nagayama,Daisuke Obata,Masahiko Higashiyama,Akihide Masumoto,Yukihiro Koretsune,Kaoru Ito,Chikashi Terao,Toshimasa Yamauchi,Issei Komuro,Takashi Kadowaki,Gen Tamiya,Masayuki Yamamoto,Yusuke Nakamura,Michiaki Kubo,Yoshinori Murakami,Kazuhiko Yamamoto,Yoichiro Kamatani,Aarno Palotie,Manuel A. Rivas,Mark J. Daly,Koichi Matsuda,Yukinori Okada,Nature Genetics,Springer Science and Business Media LLC,Vol. 53,No. 10,p. 1415-1424,2021年10月,研究論文(学術雑誌)
  • A recurrent homozygous ACTN2 variant associated with core myopathy,Inoue M,Noguchi S,Sonehara K,Nakamura-Shindo K,Taniguchi A,Kajikawa H,Nakamura H,Ishikawa K,Ogawa M,Hayashi S,Okada Y,Kuru S,Iida A,Nishino I,Acta Neuropathologica,Springer Science and Business Media LLC,Vol. 142,No. 4,p. 785-788,2021年10月,研究論文(学術雑誌)
  • Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese,Tomofuji Y,Maeda Y,Oguro-Igashira E,Kishikawa T,Yamamoto K,Sonehara K,Motooka D,Matsumoto Y,Matsuoka H,Yoshimura M,Yagita M,Nii T,Ohshima S,Nakamura S,Inohara H,Takeda K,Kumanogoh A,Okada Y,Annals of the Rheumatic Diseases,BMJ,p. annrheumdis-220687,2021年08月23日,研究論文(学術雑誌)
  • Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants,Hosoe J,Kawashima Sonoyama Y,Miya F,Kadowaki H,Suzuki K,Kato T,Matsuzawa F,Aikawa SI,Okada Y,Tsunoda T,Hanaki K,Kanzaki S,Shojima N,Yamauchi T,Kadowaki T,Diabetes,American Diabetes Association,Vol. 70,No. 8,p. 1874-1884,2021年08月,研究論文(学術雑誌)
  • Trans‐Ethnic Fine‐Mapping of the Major Histocompatibility Complex Region Linked to Parkinson's Disease,Naito T,Satake W,Ogawa K,Suzuki K,Hirata J,Foo JN,Tan EK,Toda T,Okada Y,Movement Disorders,Wiley,Vol. 36,No. 8,p. 1805-1814,2021年08月,研究論文(学術雑誌)
  • Mapping the human genetic architecture of COVID-19,Nature,Springer Science and Business Media LLC,2021年07月08日,研究論文(学術雑誌)
  • Anti‐dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles,Tsuji H,Ohmura K,Jin H,Naito R,Arase N,Kohyama M,Suenaga T,Sakakibara S,Kochi Y,Okada Y,Yamamoto K,Kikutani H,Morinobu A,Mimori T,Arase H,Arthritis & Rheumatology,Wiley,2021年06月23日,研究論文(学術雑誌)
  • Japan COVID-19 Task Force: a nation-wide consortium to elucidate host genetics of COVID-19 pandemic in Japan,Ho Namkoong,Ryuya Edahiro,Koichi Fukunaga,Yuya Shirai,Kyuto Sonehara,Hiromu Tanaka,Ho Lee,Takanori Hasegawa,Masahiro Kanai,Tatsuhiko Naito,Kenichi Yamamoto,Ryunosuke Saiki,Takayoshi Hyugaji,Eigo Shimizu,Kotoe Katayama,Kazuhisa Takahashi,Norihiro Harada,Toshio Naito,Makoto Hiki,Yasushi Matsushita,Haruhi Takagi,Ryousuke Aoki,Ai Nakamura,Sonoko Harada,Hitoshi Sasano,Hiroki Kabata,Katsunori Masaki,Hirofumi Kamata,Shinnosuke Ikemura,Shotaro Chubachi,Satoshi Okamori,Hideki Terai,Atsuho Morita,Takanori Asakura,Junichi Sasaki,Hiroshi Morisaki,Yoshifumi Uwamino,Kosaku Nanki,Yohei Mikami,Sho Uchida,Shunsuke Uno,Rino Ishihara,Yuta Matsubara,Tomoyasu Nishimura,Takanori Ogawa,Takashi Ishiguro,Taisuke Isono,Shun Shibata,Yuma Matsui,Chiaki Hosoda,Kenji Takano,Takashi Nishida,Yoichi Kobayashi,Yotaro Takaku,Noboru Takayanagi,Soichiro Ueda,Ai Tada,Masayoshi Miyawaki,Masaomi Yamamoto,Eriko Yoshida,Reina Hayashi,Tomoki Nagasaka,Sawako Arai,Yutaro Kaneko,Kana Sasaki,Etsuko Tagaya,Masatoshi Kawana,Ken Arimura,Kunihiko Takahashi,Tatsuhiko Anzai,Satoshi Ito,Akifumi Endo,Yuji Uchimura,Yasunari Miyazaki,Takayuki Honda,Tomoya Tateishi,Shuji Tohda,Naoya Ichimura,Kazunari Sonobe,Chihiro Sassa,Jun Nakajima,Yasushi Nakano,Yukiko Nakajima,Ryusuke Anan,Ryosuke Arai,Yuko Kurihara,Yuko Harada,Kazumi Nishio,Tetsuya Ueda,Masanori Azuma,Ryuichi Saito,Toshikatsu Sado,Yoshimune Miyazaki,Ryuichi Sato,Yuki Haruta,Tadao Nagasaki,Yoshinori Yasui,Yoshinori Hasegawa,Yoshikazu Mutoh,Tomonori Sato,Reoto Takei,Satoshi Hagimoto,Yoichiro Noguchi,Yasuhiko Yamano,Hajime Sasano,Sho Ota,Yasushi Nakamori,Kazuhisa Yoshiya,Fukuki Saito,Tomoyuki Yoshihara,Daiki Wada,Hiromu Iwamura,Syuji Kanayama,Shuhei Maruyama,Takashi Yoshiyama,Ken Ohta,Hiroyuki Kokuto,Hideo Ogata,Yoshiaki Tanaka,Kenichi Arakawa,Masafumi Shimoda,Takeshi Osawa,Hiroki Tateno,Isano Hase,Shuichi Yoshida,Shoji Suzuki,Miki Kawada,Hirohisa Horinouchi,Fumitake Saito,Keiko Mitamura,Masao Hagihara,Junichi Ochi,Tomoyuki Uchida,Rie Baba,Daisuke Arai,Takayuki Ogura,Hidenori Takahashi,Shigehiro Hagiwara,Genta Nagao,Shunichiro Konishi,Ichiro Nakachi,Koji Murakami,Mitsuhiro Yamada,Hisatoshi Sugiura,Hirohito Sano,Shuichiro Matsumoto,Nozomu Kimura,Yoshinao Ono,Hiroaki Baba,Yusuke Suzuki,Sohei Nakayama,Keita Masuzawa,Shinichi Namba,Ken Suzuki,Nobuyuki Hizawa,Takayuki Shiroyama,Satoru Miyawaki,Yusuke Kawamura,Akiyoshi Nakayama,Hirotaka Matsuo,Yuichi Maeda,Takuro Nii,Yoshimi Noda,Takayuki Niitsu,Yuichi Adachi,Takatoshi Enomoto,Saori Amiya,Reina Hara,Toshihiro Kishikawa,Shuhei Yamada,Shuhei Kawabata,Noriyuki Kijima,Masatoshi Takagaki,Noa Sasa,Yuya Ueno,Motoyuki Suzuki,Norihiko Takemoto,Hirotaka Eguchi,Takahito Fukusumi,Takao Imai,Munehisa Fukushima,Haruhiko Kishima,Hidenori Inohara,Kazunori Tomono,Kazuto Kato,Meiko Takahashi,Fumihiko Matsuda,Haruhiko Hirata,Yoshito Takeda,Hidefumi Koh,Tadashi Manabe,Yohei Funatsu,Fumimaro Ito,Takahiro Fukui,Keisuke Shinozuka,Sumiko Kohashi,Masatoshi Miyazaki,Tomohisa Shoko,Mitsuaki Kojima,Tomohiro Adachi,Motonao Ishikawa,Kenichiro Takahashi,Takashi Inoue,Toshiyuki Hirano,Keigo Kobayashi,Hatsuyo Takaoka,Kazuyoshi Watanabe,Naoki Miyazawa,Yasuhiro Kimura,Reiko Sado,Hideyasu Sugimoto,Akane Kamiya,Naota Kuwahara,Akiko Fujiwara,Tomohiro Matsunaga,Yoko Sato,Takenori Okada,Yoshihiro Hirai,Hidetoshi Kawashima,Atsuya Narita,Kazuki Niwa,Yoshiyuki Sekikawa,Koichi Nishi,Masaru Nishitsuji,Mayuko Tani,Junya Suzuki,Hiroki Nakatsumi,Takashi Ogura,Hideya Kitamura,Eri Hagiwara,Kota Murohashi,Hiroko Okabayashi,Takao Mochimaru,Shigenari Nukaga,Ryosuke Satomi,Yoshitaka Oyamada,Nobuaki Mori,Tomoya Baba,Yasutaka Fukui,Mitsuru Odate,Shuko Mashimo,Yasushi Makino,Kazuma Yagi,Mizuha Hashiguchi,Junko Kagyo,Tetsuya Shiomi,Satoshi Fuke,Hiroshi Saito,Tomoya Tsuchida,Shigeki Fujitani,Mumon Takita,Daiki Morikawa,Toru Yoshida,Takehiro Izumo,Minoru Inomata,Naoyuki Kuse,Nobuyasu Awano,Mari Tone,Akihiro Ito,Yoshihiko Nakamura,Kota Hoshino,Junichi Maruyama,Hiroyasu Ishikura,Tohru Takata,Toshio Odani,Masaru Amishima,Takeshi Hattori,Yasuo Shichinohe,Takashi Kagaya,Toshiyuki Kita,Kazuhide Ohta,Satoru Sakagami,Kiyoshi Koshida,Kentaro Hayashi,Tetsuo Shimizu,Yutaka Kozu,Hisato Hiranuma,Yasuhiro Gon,Namiki Izumi,Kaoru Nagata,Ken Ueda,Reiko Taki,Satoko Hanada,Kodai Kawamura,Kazuya Ichikado,Kenta Nishiyama,Hiroyuki Muranaka,Kazunori Nakamura,Naozumi Hashimoto,Keiko Wakahara,Sakamoto Koji,Norihito Omote,Akira Ando,Nobuhiro Kodama,Yasunari Kaneyama,Shunsuke Maeda,Takashige Kuraki,Takemasa Matsumoto,Koutaro Yokote,Taka-Aki Nakada,Ryuzo Abe,Taku Oshima,Tadanaga Shimada,Masahiro Harada,Takeshi Takahashi,Hiroshi Ono,Toshihiro Sakurai,Takayuki Shibusawa,Yoshifumi Kimizuka,Akihiko Kawana,Tomoya Sano,Chie Watanabe,Ryohei Suematsu,Hisako Sageshima,Ayumi Yoshifuji,Kazuto Ito,Saeko Takahashi,Kota Ishioka,Morio Nakamura,Makoto Masuda,Aya Wakabayashi,Hiroki Watanabe,Suguru Ueda,Masanori Nishikawa,Yusuke Chihara,Mayumi Takeuchi,Keisuke Onoi,Jun Shinozuka,Atsushi Sueyoshi,Yoji Nagasaki,Masaki Okamoto,Sayoko Ishihara,Masatoshi Shimo,Yoshihisa Tokunaga,Yu Kusaka,Takehiko Ohba,Susumu Isogai,Aki Ogawa,Takuya Inoue,Satoru Fukuyama,Yoshihiro Eriguchi,Akiko Yonekawa,Keiko Kan-o,Koichiro Matsumoto,Kensuke Kanaoka,Shoichi Ihara,Kiyoshi Komuta,Yoshiaki Inoue,Shigeru Chiba,Kunihiro Yamagata,Yuji Hiramatsu,Hirayasu Kai,Koichiro Asano,Tsuyoshi Oguma,Yoko Ito,Satoru Hashimoto,Masaki Yamasaki,Yu Kasamatsu,Yuko Komase,Naoya Hida,Takahiro Tsuburai,Baku Oyama,Minoru Takada,Hidenori Kanda,Yuichiro Kitagawa,Tetsuya Fukuta,Takahito Miyake,Shozo Yoshida,Shinji Ogura,Shinji Abe,Yuta Kono,Yuki Togashi,Hiroyuki Takoi,Ryota Kikuchi,Shinichi Ogawa,Tomouki Ogata,Shoichiro Ishihara,Arihiko Kanehiro,Shinji Ozaki,Yasuko Fuchimo,Sae Wada,Nobukazu Fujimoto,Kei Nishiyama,Mariko Terashima,Satoru Beppu,Kosuke Yoshida,Osamu Narumoto,Hideaki Nagai,Nobuharu Ooshima,Mitsuru Motegi,Akira Umeda,Kazuya Miyagawa,Hisato Shimada,Mayu Endo,Yoshiyuki Ohira,Masafumi Watanabe,Sumito Inoue,Akira Igarashi,Masamichi Sato,Hironori Sagara,Akihiko Tanaka,Shin Ohta,Tomoyuki Kimura,Yoko Shibata,Yoshinori Tanino,Takefumi Nikaido,Hiroyuki Minemura,Yuki Sato,Yuichiro Yamada,Takuya Hashino,Masato Shinoki,Hajime Iwagoe,Hiroshi Takahashi,Kazuhiko Fujii,Hiroto Kishi,Masayuki Kanai,Tomonori Imamura,Tatsuya Yamashita,Masakiyo Yatomi,Toshitaka Maeno,Shinichi Hayashi,Mai Takahashi,Mizuki Kuramochi,Isamu Kamimaki,Yoshiteru Tominaga,Tomoo Ishii,Mitsuyoshi Utsugi,Akihiro Ono,Toru Tanaka,Takeru Kashiwada,Kazue Fujita,Yoshinobu Saito,Masahiro Seike,Yosuke Omae,Yasuhito Nannya,Takafumi Ueno,Tomomi Takano,Kazuhiko Katayama,Masumi Ai,Atsushi Kumanogoh,Toshiro Sato,Naoki Hasegawa,Katsushi Tokunaga,Makoto Ishii,Ryuji Koike,Yuko Kitagawa,Akinori Kimura,Seiya Imoto,Satoru Miyano,Seishi Ogawa,Takanori Kanai,Yukinori Okada,Cold Spring Harbor Laboratory,2021年05月18日
  • Lupus susceptibility region containing CDKN1B rs34330 mechanistically influences expression and function of multiple target genes, also linked to proliferation and apoptosis,Singh B,Maiti GP,Zhou X,Fazel-Najafabadi M,Bae SC,Sun C,Terao C,Okada Y,Chua KH,Kochi Y,Guthridge JM,Zhang H,Weirauch M,James JA,Harley JB,Varshney GK,Looger LL,Nath SK,Arthritis & Rheumatology,Wiley,2021年05月13日,研究論文(学術雑誌)
  • An X chromosome-wide meta-analysis based on Japanese cohorts revealed that non-autosomal variations are associated with serum urate,Nakatochi M,Toyoda Y,Kanai M,Nakayama A,Kawamura Y,Hishida A,Mikami H,Matsuo K,Takezaki T,Momozawa Y,Biobank Japan Project,Kamatani Y,Ichihara S,Shinomiya N,Yokota M,Wakai K,Okada Y,Matsuo H,Japan Uric Acid,Genomics Consortium,Japan Urate,Rheumatology,Oxford University Press (OUP),Vol. 60,No. 9,p. 4430-4432,2021年05月04日,研究論文(学術雑誌)
  • タンパク質立体構造解析を用いたインスリン/IGF-1受容体における遺伝子型-表現型相関の確立,細江 隼,鞁嶋 有紀,宮 冬樹,門脇 弘子,鈴木 顕,加藤 貴史,岡田 随象,角田 達彦,花木 啓一,神崎 晋,庄嶋 伸浩,山内 敏正,門脇 孝,糖尿病,(一社)日本糖尿病学会,Vol. 64,No. Suppl.1,p. III-1,2021年05月
  • Genetic analyses identify widespread sex-differential participation bias,Pirastu N,Cordioli M,Nandakumar P,Mignogna G,Abdellaoui A,Hollis B,Kanai M,Rajagopal VM,Parolo PDB,Baya N,Carey CE,Karjalainen J,Als TD,Van der Zee MD,Day FR,Ong KK,FinnGen Study,andMe Research Team,iPSYCH Consortium,Morisaki T,de Geus E,Bellocco R,Okada Y,Børglum AD,Joshi P,Auton A,Hinds D,Neale BM,Walters RK,Nivard MG,Perry JRB,Ganna A,Nature Genetics,Springer Science and Business Media LLC,Vol. 53,No. 5,p. 663-671,2021年05月,研究論文(学術雑誌)
  • Integration of genetically regulated gene expression and pharmacological library provides therapeutic drug candidates,Konuma T,Ogawa K,Okada Y,Human Molecular Genetics,Oxford University Press (OUP),Vol. 30,No. 3-4,p. 294-304,2021年04月26日,研究論文(学術雑誌)
  • Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases,Ota M,Nagafuchi Y,Hatano H,Ishigaki K,Terao C,Takeshima Y,Yanaoka H,Kobayashi S,Okubo M,Shirai H,Sugimori Y,Maeda J,Nakano M,Yamada S,Yoshida R,Tsuchiya H,Tsuchida Y,Akizuki S,Yoshifuji H,Ohmura K,Mimori T,Yoshida K,Kurosaka D,Okada M,Setoguchi K,Kaneko H,Ban N,Yabuki N,Matsuki K,Mutoh H,Oyama S,Okazaki M,Tsunoda H,Iwasaki Y,Sumitomo S,Shoda H,Kochi Y,Okada Y,Yamamoto K,Okamura T,Fujio K,Cell,Elsevier BV,Vol. 184,p. 3006-3021,2021年04月,研究論文(学術雑誌)
  • Large-scale plasma-metabolome analysis identifies potential biomarkers of psoriasis and its clinical subtypes,Kishikawa T,Arase N,Tsuji S,Maeda Y,Nii T,Hirata J,Suzuki K,Yamamoto K,Masuda T,Ogawa K,Ohshima S,Inohara H,Kumanogoh A,Fujimoto M,Okada Y,Journal of Dermatological Science,Elsevier BV,Vol. 102,p. 78-84,2021年03月,研究論文(学術雑誌)
  • Transcriptome network analyses in human coronavirus infections suggest a rational use of immunomodulatory drugs for COVID-19 therapy,Wong HS,Guo CL,Lin GH,Lee KY,Okada Y,Chang WC,Genomics,Elsevier BV,Vol. 113,No. 2,p. 564-575,2021年03月,研究論文(学術雑誌)
  • A deep learning method for HLA imputation and trans-ethnic MHC fine-mapping of type 1 diabetes,Naito T,Suzuki K,Hirata J,Kamatani Y,Matsuda K,Toda T,Okada Y,Nature Communications,Springer Science and Business Media LLC,Vol. 12,No. 1,2021年03月,研究論文(学術雑誌)
  • Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power,Atkinson EG,Maihofer AX,Kanai M,Martin AR,Karczewski KJ,Santoro ML,Ulirsch JC,Kamatani Y,Okada Y,Finucane HK,Koenen KC,Nievergelt CM,Daly MJ,Neale BM,Nature Genetics,Springer Science and Business Media LLC,Vol. 53,No. 2,p. 195-204,2021年02月,研究論文(学術雑誌)
  • Elucidation of disease etiology by trans-layer omics analysis,Shirai Y,Okada,Inflammation and Regeneration,Springer Science and Business Media LLC,Vol. 41,No. 1,2021年02月,研究論文(学術雑誌)
  • Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis,Sakaue S,Yamaguchi E,Inoue Y,Takahashi M,Hirata J,Suzuki K,Ito S,Arai T,Hirose M,Tanino Y,Nikaido T,Ichiwata T,Ohkouchi S,Hirano T,Takada T,Miyawaki S,Dofuku S,Maeda Y,Nii T,Kishikawa T,Ogawa K,Masuda T,Yamamoto K,Sonehara K,Tazawa R,Morimoto K,Takaki M,Konno S,Suzuki M,Tomii K,Nakagawa A,Handa T,Tanizawa K,Ishii H,Ishida M,Kato T,Takeda N,Yokomura K,Matsui T,Watanabe M,Inoue H,Imaizumi K,Goto Y,Kida H,Fujisawa T,Suda T,Yamada T,Satake Y,Ibata H,Hizawa N,Mochizuki H,Kumanogoh A,Matsuda F,Nakata K,Hirota T,Tamari M,Okada Y,Nature Communications,Springer Science and Business Media LLC,Vol. 12,No. 1,p. 1032-1032,2021年02月,研究論文(学術雑誌)
  • Increased levels of plasma nucleotides in patients with rheumatoid arthritis,Kishikawa T,Maeda Y,Nii T,Arase N,Hirata J,Suzuki K,Yamamoto K,Masuda T,Ogawa K,Tsuji S,Matsushita M,Matsuoka H,Yoshimura M,Tsunoda S,Ohshima S,Narazaki M,Ogata A,Saeki Y,Inohara H,Kumanogoh A,Takeda K,Okada Y,International Immunology,Oxford University Press (OUP),Vol. 33,No. 2,p. 119-124,2021年01月28日,研究論文(学術雑誌)
  • ゲノムワイド関連解析による病型特異的な痛風関連遺伝子の同定と日本人の適応進化,中山 昌喜,中杤 昌弘,河村 優輔,清水 聖子,東野 俊英,清水 徹,大山 恵子,大山 博司,長瀬 満夫,日高 雄二,川口 真,高田 雄三,高田 龍平,細谷 龍男,市田 公美,四ノ宮 成祥,松尾 洋孝,山本 健,中岡 博史,菱田 朝陽,中村 好宏,中島 宏,豊田 優,鎌谷 洋一郎,久保 充明,若井 建志,岡田 随象,日本痛風・尿酸核酸学会総会プログラム・抄録集,(一社)日本痛風・尿酸核酸学会,Vol. 54回,p. 88-88,2021年01月
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  • Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan.,Sakaue S,Kanai M,Karjalainen J,Akiyama M,Kurki M,Matoba N,Takahashi A,Hirata M,Kubo M,Matsuda K,Murakami Y,FinnGen,Daly MJ,Kamatani Y,Okada Y,Nature Medicine,Springer Science and Business Media LLC,Vol. 26,No. 4,p. 542-548,2020年04月,研究論文(学術雑誌)
  • Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction.,Sakaue S,Hirata J,Kanai M,Suzuki K,Akiyama M,Lai Too C,Arayssi T,Hammoudeh M,Al Emadi S,Masri BK,Halabi H,Badsha H,Uthman IW,Saxena R,Padyukov L,Hirata M,Matsuda K,Murakami Y,Kamatani Y,Okada Y,Nature Communications,Vol. 11,No. 1,p. 1569-1569,2020年03月26日,研究論文(学術雑誌)
  • Response to: ‘Can sexual dimorphism in rheumatoid arthritis be attributed to the different abundance of Gardnerella?’ by Liu et al,Kishikawa T,Maeda Y,Nii T,Okada Y,Annals of the Rheumatic Diseases,BMJ,p. annrheumdis-2020,2020年03月25日,研究論文(学術雑誌)
  • Author Correction: Characterizing rare and low-frequency height-associated variants in the Japanese population.,Akiyama M,Ishigaki K,Sakaue S,Momozawa Y,Horikoshi M,Hirata M,Matsuda K,Ikegawa S,Takahashi A,Kanai M,Suzuki S,Matsui D,Naito M,Yamaji T,Iwasaki M,Sawada N,Tanno K,Sasaki M,Hozawa A,Minegishi N,Wakai K,Tsugane S,Shimizu A,Yamamoto M,Okada Y,Murakami Y,Kubo M,Kamatani Y,Nat Commun,Vol. 11,No. 1,p. 1350-1350,2020年03月09日
  • Genetic and phenotypic landscape of the mitochondrial genome in the Japanese population.,Yamamoto K,Sakaue S,Matsuda K,Murakami Y,Kamatani Y,Ozono K,Momozawa Y,Okada Y,Communications Biology,Vol. 3,No. 1,p. 104-104,2020年03月05日,研究論文(学術雑誌)
  • Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis.,Amariuta T,Luo Y,Knevel R,Okada Y,Raychaudhuri S,Immunol Rev,Vol. 294,No. 1,p. 188-204,2020年03月,研究論文(学術雑誌)
  • GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits.,Matoba N,Akiyama M,Ishigaki K,Kanai M,Takahashi A,Momozawa Y,Ikegawa S,Ikeda M,Iwata N,Hirata M,Matsuda K,Murakami Y,Kubo M,Kamatani Y,Okada Y,Nature Human Behaviour,Vol. 4,No. 3,p. 308-316,2020年03月,研究論文(学術雑誌)
  • Parental somatogonadal COL2A1 mosaicism contributes to intrafamilial recurrence in a family with type 2 collagenopathy.,Yamamoto K,Kubota T,Takeyari S,Kitaoka T,Miyata K,Nakano Y,Nakayama H,Ohata Y,Yanagi K,Kaname T,Okada Y,Ozono K,American Journal of Medical Genetics Part A,Vol. 182,No. 3,p. 454-460,2020年03月,研究論文(学術雑誌)
  • Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population.,Sakaue S,Akiyama M,Hirata M,Matsuda K,Murakami Y,Kubo M,Kamatani Y,Okada Y,European Journal of Human Genetics,Vol. 28,No. 3,p. 378-382,2020年03月,研究論文(学術雑誌)
  • Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population.,Kishikawa T,Maeda Y,Nii T,Motooka D,Matsumoto Y,Matsushita M,Matsuoka H,Yoshimura M,Kawada S,Teshigawara S,Oguro E,Okita Y,Kawamoto K,Higa S,Hirano T,Narazaki M,Ogata A,Saeki Y,Nakamura S,Inohara H,Kumanogoh A,Takeda K,Okada Y,Annals of the Rheumatic Diseases,BMJ,Vol. 79,No. 1,p. 103-111,2020年01月,研究論文(学術雑誌)
  • GWAS of five gynecologic diseases and cross-trait analysis in Japanese.,Masuda T,Low SK,Akiyama M,Hirata M,Ueda Y,Matsuda K,Kimura T,Murakami Y,Kubo M,Kamatani Y,Okada Y,European Journal of Human Genetics,Vol. 28,No. 1,p. 95-107,2020年01月,研究論文(学術雑誌)
  • Biological characterization of expression quantitative trait loci (eQTLs) showing tissue-specific opposite directional effects.,Mizuno A,Okada Y,European Journal of Human Genetics,Vol. 27,No. 11,p. 1745-1756,2019年11月,研究論文(学術雑誌)
  • Comparison of diagnostic precision for bone metastasis of primary breast cancer between BONENAVI version 1 and BONENAVI version 2.,Okada Y,Matsushita S,Nakajima Y,Yamaguchi K,Okuda I,Kojima Y,Tsugawa K,Nuclear medicine communications,Vol. 40,No. 11,p. 1148-1153,2019年11月,研究論文(学術雑誌)
  • Polygenic burden in focal and generalized epilepsies.,Leu C,Stevelink R,Smith AW,Goleva SB,Kanai M,Ferguson L,Campbell C,Kamatani Y,Okada Y,Sisodiya SM,Cavalleri GL,Koeleman BPC,Lerche H,Jehi L,Davis LK,Najm IM,Palotie A,Daly MJ,Busch RM,Epi,Consortium, Lal D,Brain : a journal of neurology,Vol. 142,No. 11,p. 3473-3481,2019年11月01日,研究論文(学術雑誌)
  • Shared genetic factors and their causality in autoimmune diseases,Yamamoto K,Okada Y,Annals of the Rheumatic Diseases,BMJ,Vol. 78,No. 11,p. 1449-1451,2019年11月,研究論文(学術雑誌)
  • HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy.,Noguchi E,Akiyama M,Yagami A,Hirota T,Okada Y,Kato Z,Kishikawa R,Fukutomi Y,Hide M,Morita E,Aihara M,Hiragun M,Chinuki Y,Okabe T,Ito A,Adachi A,Fukunaga A,Kubota Y,Aoki T,Aoki Y,Nishioka K,Adachi T,Kanazawa N,Miyazawa H,Sakai H,Kozuka T,Kitamura H,Hashizume H,Kanegane C,Masuda K,Sugiyama K,Tokuda R,Furuta J,Higashimoto I,Kato A,Seishima M,Tajiri A,Tomura A,Taniguchi H,Kojima H,Tanaka H,Sakai A,Morii W,Nakamura M,Kamatani Y,Takahashi A,Kubo M,Tamari M,Saito H,Matsunaga K,The Journal of allergy and clinical immunology,Vol. 144,No. 5,p. 1354-1363,2019年11月,研究論文(学術雑誌)
  • Associations of autozygosity with a broad range of human phenotypes.,Clark DW,Okada Y,Moore KHS,Mason D,Pirastu N,Gandin I,Mattsson H,Barnes CLK,Lin K,Zhao JH,Deelen P,Rohde R,Schurmann C,Guo X,Giulianini F,Zhang W,Medina-Gomez C,Karlsson R,Bao Y,Bartz TM,Baumbach C,Biino G,Bixley MJ,Brumat M,Chai JF,Corre T,Cousminer DL,Dekker AM,Eccles DA,van Eijk KR,Fuchsberger C,Gao H,Germain M,Gordon SD,de Haan HG,Harris SE,Hofer E,Huerta-Chagoya A,Igartua C,Jansen IE,Jia Y,Kacprowski T,Karlsson T,Kleber ME,Li SA,Li-Gao R,Mahajan A,Matsuda K,Meidtner K,Meng W,Montasser ME,van der Most PJ,Munz M,Nutile T,Palviainen T,Prasad G,Prasad RB,Priyanka TDS,Rizzi F,Salvi E,Sapkota BR,Shriner D,Skotte L,Smart MC,Smith AV,van der Spek A,Spracklen CN,Strawbridge RJ,Tajuddin SM,Trompet S,Turman C,Verweij N,Viberti C,Wang L,Warren HR,Wootton RE,Yanek LR,Yao J,Yousri NA,Zhao W,Adeyemo AA,Afaq S,Aguilar-Salinas CA,Akiyama M,Albert ML,Allison MA,Alver M,Aung T,Azizi F,Bentley AR,Boeing H,Boerwinkle E,Borja JB,de Borst GJ,Bottinger EP,Broer L,Campbell H,Chanock S,Chee ML,Chen G,Chen YI,Chen Z,Chiu YF,Cocca M,Collins FS,Concas MP,Corley J,Cugliari G,van Dam RM,Damulina A,Daneshpour MS,Day FR,Delgado GE,Dhana K,Doney ASF,Dörr M,Doumatey AP,Dzimiri N,Ebenesersdóttir SS,Elliott J,Elliott P,Ewert R,Felix JF,Fischer K,Freedman BI,Girotto G,Goel A,Gögele M,Goodarzi MO,Graff M,Granot-Hershkovitz E,Grodstein F,Guarrera S,Gudbjartsson DF,Guity K,Gunnarsson B,Guo Y,Hagenaars SP,Haiman CA,Halevy A,Harris TB,Hedayati M,van Heel DA,Hirata M,Höfer I,Hsiung CA,Huang J,Hung YJ,Ikram MA,Jagadeesan A,Jousilahti P,Kamatani Y,Kanai M,Kerrison ND,Kessler T,Khaw KT,Khor CC,de Kleijn DPV,Koh WP,Kolcic I,Kraft P,Krämer BK,Kutalik Z,Kuusisto J,Langenberg C,Launer LJ,Lawlor DA,Lee IT,Lee WJ,Lerch MM,Li L,Liu J,Loh M,London SJ,Loomis S,Lu Y,Luan J,Mägi R,Manichaikul AW,Manunta P,Másson G,Matoba N,Mei XW,Meisinger C,Meitinger T,Mezzavilla M,Milani L,Millwood IY,Momozawa Y,Moore A,Morange PE,Moreno-Macías H,Mori TA,Morrison AC,Muka T,Murakami Y,Murray AD,de Mutsert R,Mychaleckyj JC,Nalls MA,Nauck M,Neville MJ,Nolte IM,Ong KK,Orozco L,Padmanabhan S,Pálsson G,Pankow JS,Pattaro C,Pattie A,Polasek O,Poulter N,Pramstaller PP,Quintana-Murci L,Räikkönen K,Ralhan S,Rao DC,van Rheenen W,Rich SS,Ridker PM,Rietveld CA,Robino A,van Rooij FJA,Ruggiero D,Saba Y,Sabanayagam C,Sabater-Lleal M,Sala CF,Salomaa V,Sandow K,Schmidt H,Scott LJ,Scott WR,Sedaghati-Khayat B,Sennblad B,van Setten J,Sever PJ,Sheu WH,Shi Y,Shrestha S,Shukla SR,Sigurdsson JK,Sikka TT,Singh JR,Smith BH,Stančáková A,Stanton A,Starr JM,Stefansdottir L,Straker L,Sulem P,Sveinbjornsson G,Swertz MA,Taylor AM,Taylor KD,Terzikhan N,Tham YC,Thorleifsson G,Thorsteinsdottir U,Tillander A,Tracy RP,Tusié-Luna T,Tzoulaki I,Vaccargiu S,Vangipurapu J,Veldink JH,Vitart V,Völker U,Vuoksimaa E,Wakil SM,Waldenberger M,Wander GS,Wang YX,Wareham NJ,Wild S,Yajnik CS,Yuan JM,Zeng L,Zhang L,Zhou J,Amin N,Asselbergs FW,Bakker SJL,Becker DM,Lehne B,Bennett DA,van den Berg LH,Berndt SI,Bharadwaj D,Bielak LF,Bochud M,Boehnke M,Bouchard C,Bradfield JP,Brody JA,Campbell A,Carmi S,Caulfield MJ,Cesarini D,Chambers JC,Chandak GR,Cheng CY,Ciullo M,Cornelis M,Cusi D,Smith GD,Deary IJ,Dorajoo R,van Duijn CM,Ellinghaus D,Erdmann J,Eriksson JG,Evangelou E,Evans MK,Faul JD,Feenstra B,Feitosa M,Foisy S,Franke A,Friedlander Y,Gasparini P,Gieger C,Gonzalez C,Goyette P,Grant SFA,Griffiths LR,Groop L,Gudnason V,Gyllensten U,Hakonarson H,Hamsten A,van der Harst P,Heng CK,Hicks AA,Hochner H,Huikuri H,Hunt SC,Jaddoe VWV,De Jager PL,Johannesson M,Johansson Å,Jonas JB,Jukema JW,Junttila J,Kaprio J,Kardia SLR,Karpe F,Kumari M,Laakso M,van der Laan SW,Lahti J,Laudes M,Lea RA,Lieb W,Lumley T,Martin NG,März W,Matullo G,McCarthy MI,Medland SE,Merriman TR,Metspalu A,Meyer BF,Mohlke KL,Montgomery GW,Mook-Kanamori D,Munroe PB,North KE,Nyholt DR,O'connell JR,Ober C,Oldehinkel AJ,Palmas W,Palmer C,Pasterkamp GG,Patin E,Pennell CE,Perusse L,Peyser PA,Pirastu M,Polderman TJC,Porteous DJ,Posthuma D,Psaty BM,Rioux JD,Rivadeneira F,Rotimi C,Rotter JI,Rudan I,Den Ruijter HM,Sanghera DK,Sattar N,Schmidt R,Schulze MB,Schunkert H,Scott RA,Shuldiner AR,Sim X,Small N,Smith JA,Sotoodehnia N,Tai ES,Teumer A,Timpson NJ,Toniolo D,Tregouet DA,Tuomi T,Vollenweider P,Wang CA,Weir DR,Whitfield JB,Wijmenga C,Wong TY,Wright J,Yang J,Yu L,Zemel BS,Zonderman AB,Perola M,Magnusson PKE,Uitterlinden AG,Kooner JS,Chasman DI,Loos RJF,Franceschini N,Franke L,Haley CS,Hayward C,Walters RG,Perry JRB,Esko T,Helgason A,Stefansson K,Joshi PK,Kubo M,Wilson JF,Nature communications,Springer Science and Business Media LLC,Vol. 10,No. 1,p. 4957-4957,2019年10月31日,研究論文(学術雑誌)
  • Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.,Tin A,Marten J,Halperin Kuhns VL,Li Y,Wuttke M,Kirsten H,Sieber KB,Qiu C,Gorski M,Yu Z,Giri A,Sveinbjornsson G,Li M,Chu AY,Hoppmann A,O'Connor LJ,Prins B,Nutile T,Noce D,Akiyama M,Cocca M,Ghasemi S,van der Most PJ,Horn K,Xu Y,Fuchsberger C,Sedaghat S,Afaq S,Amin N,Ärnlöv J,Bakker SJL,Bansal N,Baptista D,Bergmann S,Biggs ML,Biino G,Boerwinkle E,Bottinger EP,Boutin TS,Brumat M,Burkhardt R,Campana E,Campbell A,Campbell H,Carroll RJ,Catamo E,Chambers JC,Ciullo M,Concas MP,Coresh J,Corre T,Cusi D,Felicita SC,de Borst MH,De Grandi A,de Mutsert R,de Vries APJ,Delgado G,Demirkan A,Devuyst O,Dittrich K,Eckardt KU,Ehret G,Endlich K,Evans MK,Gansevoort RT,Gasparini P,Giedraitis V,Gieger C,Girotto G,Gögele M,Gordon SD,Gudbjartsson DF,Gudnason V,German Chronic Kidney,Disease Study,Haller T,Hamet P,Harris TB,Hayward C,Hicks AA,Hofer E,Holm H,Huang W,Hutri-Kähönen N,Hwang SJ,Ikram MA,Lewis RM,Ingelsson E,Jakobsdottir J,Jonsdottir I,Jonsson H,Joshi PK,Josyula NS,Jung B,Kähönen M,Kamatani Y,Kanai M,Kerr SM,Kiess W,Kleber ME,Koenig W,Kooner JS,Körner A,Kovacs P,Krämer BK,Kronenberg F,Kubo M,Kühnel B,La Bianca M,Lange LA,Lehne B,Lehtimäki T,Lifelines Cohort Study,Liu J,Loeffler M,Loos RJF,Lyytikäinen LP,Magi R,Mahajan A,Martin NG,März W,Mascalzoni D,Matsuda K,Meisinger C,Meitinger T,Metspalu A,Milaneschi Y,V. A. Million Veteran Program,O'Donnell CJ,Wilson OD,Gaziano JM,Mishra PP,Mohlke KL,Mononen N,Montgomery GW,Mook-Kanamori DO,Müller-Nurasyid M,Nadkarni GN,Nalls MA,Nauck M,Nikus K,Ning B,Nolte IM,Noordam R,O'Connell JR,Olafsson I,Padmanabhan S,Penninx BWJH,Perls T,Peters A,Pirastu M,Pirastu N,Pistis G,Polasek O,Ponte B,Porteous DJ,Poulain T,Preuss MH,Rabelink TJ,Raffield LM,Raitakari OT,Rettig R,Rheinberger M,Rice KM,Rizzi F,Robino A,Rudan I,Krajcoviechova A,Cifkova R,Rueedi R,Ruggiero D,Ryan KA,Saba Y,Salvi E,Schmidt H,Schmidt R,Shaffer CM,Smith AV,Smith BH,Spracklen CN,Strauch K,Stumvoll M,Sulem P,Tajuddin SM,Teren A,Thiery J,Thio CHL,Thorsteinsdottir U,Toniolo D,Tönjes A,Tremblay J,Uitterlinden AG,Vaccargiu S,van der Harst P,van Duijn CM,Verweij N,Völker U,Vollenweider P,Waeber G,Waldenberger M,Whitfield JB,Wild SH,Wilson JF,Yang Q,Zhang W,Zonderman AB,Bochud M,Wilson JG,Pendergrass SA,Ho K,Parsa A,Pramstaller PP,Psaty BM,Böger CA,Snieder H,Butterworth AS,Okada Y,Edwards TL,Stefansson K,Susztak K,Scholz M,Heid IM,Hung AM,Teumer A,Pattaro C,Woodward OM,Vitart V,Köttgen A,Nature genetics,Vol. 51,No. 10,p. 1459-1474,2019年10月,研究論文(学術雑誌)
  • GREP: genome for REPositioning drugs.,Sakaue S,Okada Y,Bioinformatics,Vol. 35,No. 19,p. 3821-3823,2019年10月01日,研究論文(学術雑誌)
  • Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.,Kawamura Y,Nakaoka H,Nakayama A,Okada Y,Yamamoto K,Higashino T,Sakiyama M,Shimizu T,Ooyama H,Ooyama K,Nagase M,Hidaka Y,Shirahama Y,Hosomichi K,Nishida Y,Shimoshikiryo I,Hishida A,Katsuura-Kamano S,Shimizu S,Kawaguchi M,Uemura H,Ibusuki R,Hara M,Naito M,Takao M,Nakajima M,Iwasawa S,Nakashima H,Ohnaka K,Nakamura T,Stiburkova B,Merriman TR,Nakatochi M,Ichihara S,Yokota M,Takada T,Saitoh T,Kamatani Y,Takahashi A,Arisawa K,Takezaki T,Tanaka K,Wakai K,Kubo M,Hosoya T,Ichida K,Inoue I,Shinomiya N,Matsuo H,Annals of the Rheumatic Diseases,BMJ,Vol. 78,No. 10,p. 1430-1437,2019年10月,研究論文(学術雑誌)
  • Characterizing rare and low-frequency height-associated variants in the Japanese population.,Akiyama M,Ishigaki K,Sakaue S,Momozawa Y,Horikoshi M,Hirata M,Matsuda K,Ikegawa S,Takahashi A,Kanai M,Suzuki S,Matsui D,Naito M,Yamaji T,Iwasaki M,Sawada N,Tanno K,Sasaki M,Hozawa A,Minegishi N,Wakai K,Tsugane S,Shimizu A,Yamamoto M,Okada Y,Murakami Y,Kubo M,Kamatani Y,Nature Communications,Springer Science and Business Media LLC,Vol. 10,No. 1,p. 4393-4393,2019年09月27日,研究論文(学術雑誌)
  • Next-generation sequencing identifies contribution of both class I and II HLA genes on susceptibility of multiple sclerosis in Japanese.,Ogawa K,Okuno T,Hosomichi K,Hosokawa A,Hirata J,Suzuki K,Sakaue S,Kinoshita M,Asano Y,Miyamoto K,Inoue I,Kusunoki S,Okada Y,Mochizuki H,Journal of neuroinflammation,Vol. 16,No. 1,p. 162-162,2019年08月05日,研究論文(学術雑誌)
  • GNEミオパチーp.D207V変異は軽症型変異であり、ホモ接合体では極めて稀にしか発症しない,吉岡 和香子,飯田 有俊,岡田 随象,大矢 寧,大久保 真理子,小川 恵,松田 文彦,日笠 幸一郎,森 まどか,中村 治雅,林 晋一郎,野口 悟,西野 一三,日本筋学会学術集会プログラム・抄録集,日本筋学会,Vol. 5回,p. 111-111,2019年08月
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  • Amino acid position 37 of HLA-DRβ1 affects susceptibility to Crohn's disease in Asians.,Han B,Akiyama M,Kim KK,Oh H,Choi H,Lee CH,Jung S,Lee HS,Kim EE,Cook S,Haritunians T,Yamazaki K,Park SH,Ye BD,McGovern DPB,Esaki M,Kawaguchi T,Khor SS,Taylor KD,Rotter JI,Suzuki Y,Matsui T,Motoya S,Bang SY,Kim TH,Momozawa Y,Kamatani Y,Tokunaga K,Kubo M,Okada Y,Yang SK,Song K,Human molecular genetics,Vol. 27,No. 22,p. 3901-3910,2018年11月15日,研究論文(学術雑誌)
  • In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.,Uenaka T,Satake W,Cha PC,Hayakawa H,Baba K,Jiang S,Kobayashi K,Kanagawa M,Okada Y,Mochizuki H,Toda T,Human molecular genetics,Oxford University Press (OUP),Vol. 27,No. 22,p. 3974-3985,2018年11月15日,研究論文(学術雑誌)
  • Usefulness of the combination of iodine-123-metaiodobenzylguanidine scintigraphy and iodine-123-ioflupane scintigraphy in new-onset Parkinson's disease.,Yukinori Okada,Makoto Shiraishi,Hisao Nakamura,Futaba Maki,Naoshi Sasaki,Yasuhiro Hasegawa,Oga Sasaki,Yasuo Nakashima,Nuclear medicine communications,Vol. 39,No. 11,p. 983-988,2018年11月,研究論文(学術雑誌)
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  • Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis.,Li G†,Martínez-Bonet M,Wu D,Yang Y,Cui J,Nguyen HN,Cunin P,Levescot A,Bai M,Westra HJ,Okada Y,Brenner MB,Raychaudhuri S,Hendrickson EA,Maas RL,Nigrovic PA,Annals of the rheumatic diseases,Vol. 77,No. 10,p. 1454-1462,2018年10月,研究論文(学術雑誌)
  • High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction.,Gang Li,Marta Martínez-Bonet,Di Wu,Yu Yang,Jing Cui,Hung N Nguyen,Pierre Cunin,Anaïs Levescot,Ming Bai,Harm-Jan Westra,Yukinori Okada,Michael B Brenner,Soumya Raychaudhuri,Eric A Hendrickson,Richard L Maas,Peter A Nigrovic,Nature genetics,Vol. 50,No. 8,p. 1180-1188,2018年08月,研究論文(学術雑誌)
  • Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese.,Okada Y,Momozawa Y,Sakaue S,Kanai M,Ishigaki K,Akiyama M,Kishikawa T,Arai Y,Sasaki T,Kosaki K,Suematsu M,Matsuda K,Yamamoto K,Kubo M,Hirose N,Kamatani Y,Nature communications,Springer Science and Business Media LLC,Vol. 9,No. 1,p. 1631-1631,2018年04月24日,研究論文(学術雑誌)
  • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.,Malik R,Chauhan C,Traylor M,Sargurupremraj M,Okada Y,Mishra A,Rutten-Jacobs L,Giese AK,van der Laan SW,Gretarsdottir S,Anderson CD,Chong M,Adams HHH,Ago T,Almgren P,Amouyel P,Ay H,Bartz TM,Benavente OR,Bevan A,Boncoraglio GB,Brown,Jr. RD,Butterworth AS,Carrera C,Carty CL,Chasman DI,Chen W,Cole JW,Correa A,Cotlarciuc I,Cruchaga C,Danesh J,de Bakker PIW,DeStefano AL,den Hoed M,Duan Q,Engelter ST,Falcone GJ,Gottesman RF,Grewal RP,Gudnason V,Gustafsson S,Haessler J,Harris TB,Hassan A,Havulinna AS,Heckbert SR,Holliday EG,Howard G,Hsu F,Hyacinth HI,Ikram MA,Ingelsson E,Irvin MR,Jian X,Jiménez-Conde J,Johnson JA,Jukema JW,Kanai M,Keene KL,Kissela BM,Kleindorfer DO,Kooperberg C,Kubo M,Lange L,Langefeld CD,Langenberg C,Launer LJ,Lee J,Lemmens ,R Leys D,Lewis CM,Lin W,Lindgren AG,Lorentzen E,Magnusson PK,Maguire J,Manichaikul A,McArdle PF,Meschia JF,Mitchell BD,Mosley TH,Nalls MA,Ninomiya T,O'Donnell MJ,Psaty BM,Pulit AL,Rannikmäe K,Reiner AP,Rexrode KM,Rice K,Rich SS,Ridker PM,Rost NS,Rothwell PM,Rotter JI,Rundek T,Sacco RL,Sakaue S,Sale MM,Salomaa V,Sapkota BR,Schmidt R,Schmidt CO,Schminke U,Sharma P,Slowik A,Sudlow CLM,Tanislav C,Tatlisumak T,Taylor KD,Thijs VNS,Thorleifsson G,Thorsteinsdottir U,Tiedt S,Trompet S,Tzourio C,van Duijn CM,Walters M,Wareham NJ,Wassertheil-Smoller S,Wilson JG,Wiggins KL,Yang Q,Yusuf S,AFGen consortium,CHARGE Consortium,iGEN-BP Consortium,INVENT consortium,STARNET,Bis JC,Pastinen T,Ruusalepp A,Schadt E,Koplev S,Björkegren JLM,Codoni V,Civelek M,Smith N,Trégouët DA,Christophersen IE,Roselli C,Lubitz SA,Ellinor PT,Tai ES,Kooner JS,Kato N,He J,van der Harst P,Elliott P,Chambers JC,Takeuchi F,Johnson AD,BioBank Japan,COMPASS consortium,EPIC-CVD consortium,EPIC-InterAct consortium,ISGC,METASTROKE Consortium,Neurology Working,Group of,CHARGE Consortium,NINDS SiGN,UK Young Lacunar,DNA Study,Sanghera DK,Melander O,Jern C,Strbian D,Fernandez-Cadenas I, Longstreth,Jr WT,Rolfs A,Hata J,Woo D,Rosand J,Pare G,Hopewell JC,Saleheen D,Stefansson K,Worrall BB†,Kittner SJ,Seshadri S,Fornage M,Markus HS†,Howson JMM,Kamatani Y,Debette S,Dichgans M,Nature genetics,Springer Science and Business Media LLC,Vol. 50,No. 4,p. 524-537,2018年04月,研究論文(学術雑誌)
  • Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese.,Hirata J,Hirota T,Ozeki T,Kanai M,Sudo T,Tanaka T,Hizawa N,Nakagawa H,Sato S,Mushiroda T,Saeki H,Tamari M,Okada Y,The Journal of investigative dermatology,Elsevier BV,Vol. 138,No. 3,p. 542-548,2018年03月,研究論文(学術雑誌)
  • Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.,Kanai M,Akiyama M,Takahashi A,Matoba N,Momozawa Y,Ikeda M,Iwata N,Ikegawa S,Hirata M,Matsuda K,Kubo M,Okada Y,Kamatani Y,Nature genetics,Springer Science and Business Media LLC,Vol. 50,No. 3,p. 390-400,2018年03月,研究論文(学術雑誌)
  • Statistical genetics and its application to neuroimmunology,Ogawa K,Okada Y,Clinical and Experimental Neuroimmunology,Wiley,Vol. 9,No. 1,p. 7-12,2018年02月,研究論文(学術雑誌)
  • eLD: entropy-based linkage disequilibrium index between multiallelic sites.,Okada Y,Human genome variation,Vol. 5,p. 29-29,2018年,研究論文(学術雑誌)
  • A common variant of MAF/c-MAF, transcriptional factor gene in the kidney, is associated with gout susceptibility.,Higashino T,Matsuo H,Okada Y,Nakashima H,Shimizu S,Sakiyama M,Tadokoro S,Nakayama A,Kawaguchi M,Komatsu M,Hishida A,Nakatochi M,Ooyama H,Imaki J,Shinomiya N,Human cell,Springer Science and Business Media LLC,Vol. 31,No. 1,p. 10-13,2018年01月,研究論文(学術雑誌)
  • Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population.,Terao C,Okada Y,Ikari K,Kochi Y,Suzuki A,Ohmura K,Matsuo K,Taniguchi A,Kubo M,Raychaudhuri S,Yamamoto K,Yamanaka H,Kamatani Y,Mimori T,Matsuda F,Journal of medical genetics,BMJ,Vol. 54,No. 12,p. 853-858,2017年12月,研究論文(学術雑誌)
  • Human genetics contributes to the understanding of disease pathophysiology and drug discovery.,Sakaue S,Okada Y,Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association,Elsevier BV,Vol. 22,No. 6,p. 977-981,2017年11月,研究論文(学術雑誌)
  • Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.,Akiyama M,Okada Y,Kanai M,Takahashi A,Momozawa Y,Ikeda M,Iwata N,Ikegawa S,Hirata M,Matsuda K,Iwasaki M,Yamaji T,Sawada N,Hachiya T,Tanno K,Shimizu A,Hozawa A,Minegishi N,Tsugane S,Yamamoto M,Kubo M,Kamatani Y,Nature genetics,Springer Science and Business Media LLC,Vol. 49,No. 10,p. 1458-1467,2017年10月,研究論文(学術雑誌)
  • rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis.,Chen WC,Wang WC,Okada Y,Chang WP,Chou YH,Chang HH,Huang JD,Chen DY†,Chang WC,Oncotarget,Impact Journals, LLC,Vol. 8,No. 38,p. 64180-64190,2017年09月08日,研究論文(学術雑誌)
  • Association of NOD2 Mutations with Aggressive Periodontitis,T. Sudo,Y. Okada,K. Ozaki,K. Urayama,M. Kanai,H. Kobayashi,M. Gokyu,Y. Izumi,T. Tanaka,Journal of Dental Research,SAGE Publications,Vol. 96,No. 10,p. 1100-1105,2017年09月,研究論文(学術雑誌)
  • Future Directions of Genomics Research in Rheumatic Diseases.,Okada Y,Kishikawa T,Sakaue S,Hirata J,Rheumatic diseases clinics of North America,Elsevier BV,Vol. 43,No. 3,p. 481-487,2017年08月,研究論文(学術雑誌)
  • Data Sparsity in Study on Human Leukocyte Antigen Class I Genes Associated With Stevens-Johnson Syndrome and Severe Ocular Complications-Reply.,Yukinori Okada,Mayumi Ueta,JAMA ophthalmology,American Medical Association (AMA),Vol. 135,No. 8,p. 894-895,2017年08月01日,研究論文(学術雑誌)
  • Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis.,Ishigaki K,Kochi Y,Suzuki A,Tsuchida Y,Tsuchiya H,Sumitomo S,Yamaguchi K,Nagafuchi Y,Nakachi S,Kato R,Sakurai K,Shoda H,Ikari K,Taniguchi A,Yamanaka H,Miya F,Tsunoda T,Okada Y,Momozawa Y,Kamatani Y,Yamada R,Kubo M,Fujio K,Yamamoto K,Nature genetics,Springer Science and Business Media LLC,Vol. 49,No. 7,p. 1120-1125,2017年07月,研究論文(学術雑誌)
  • GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.,Nakayama A,Nakaoka H,Yamamoto K,Sakiyama M,Shaukat A,Toyoda Y,Okada Y,Kamatani Y,Nakamura T,Takada T,Inoue K,Yasujima T,Yuasa H,Shirahama Y,Nakashima H,Shimizu S,Higashino T,Kawamura Y,Ogata H,Kawaguchi M,Ohkawa Y,Danjoh I,Tokumasu A,Ooyama K,Ito T,Kondo T,Wakai K,Stiburkova B,Pavelka K,Stamp LK,Dalbeth N,Eurogout Consortium,Sakurai Y,Suzuki H,Hosoyamada M,Fujimori S,Yokoo T,Hosoya T,Inoue I,Takahashi A,Kubo M,Ooyama H,Shimizu T,Ichida K,Shinomiya N,Merriman TR,Matsuo H,Annals of the rheumatic diseases,BMJ,Vol. 76,No. 5,p. 869-877,2017年05月,研究論文(学術雑誌)
  • A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.,Saxena R,Plenge RM,Bjonnes AC,Dashti HS,Okada Y,Gad El Haq W,Hammoudeh M,Al Emadi S,Masri BK,Halabi H,Badsha H,Uthman IW,Margolin L,Gupta N,Mahfoud ZR,Kapiri M,Dargham SR,Aranki G,Kazkaz LA,Arayssi T,Arthritis & rheumatology (Hoboken, N.J.),Wiley,Vol. 69,No. 5,p. 976-985,2017年05月,研究論文(学術雑誌)
  • Brief Report: The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis.,Cui J,Diogo D,Stahl EA,Canhao H,Mariette X,Greenberg JD,Okada Y,Pappas DA,Fulton RS,Tak PP,Nurmohamed MT,Lee A,Larson DE,Kurreeman F,Deluca TL,O'Laughlin M,Fronick CC,Fulton LL,Mardis ER,van der Horst-Bruinsma IE,Wolbink GJ,Gregersen PK,Kremer JM,Crusius JB,de Vries N,Huizinga TW,Fonseca JE,Miceli-Richard C,Karlson EW,Coenen MJ,Barton A,Plenge RM,Raychaudhuri S,Arthritis & rheumatology (Hoboken, N.J.),Wiley,Vol. 69,No. 4,p. 735-741,2017年04月,研究論文(学術雑誌)
  • Human Leukocyte Antigen Class I Genes Associated With Stevens-Johnson Syndrome and Severe Ocular Complications Following Use of Cold Medicine in a Brazilian Population.,Wakamatsu TH,Ueta M,Tokunaga K,Okada Y,Loureiro RR,Costa KA,Sallum JM,Milhomens JA,Inoue C,Sotozono C,Gomes JÁ,Kinoshita S,JAMA ophthalmology,American Medical Association (AMA),Vol. 135,No. 4,p. 355-360,2017年04月01日,研究論文(学術雑誌)
  • Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci.,Julio E Molineros,Wanling Yang,Xu-Jie Zhou,Celi Sun,Yukinori Okada,Huoru Zhang,Kek Heng Chua,Yu-Lung Lau,Yuta Kochi,Akari Suzuki,Kazuhiko Yamamoto,Jianyang Ma,So-Young Bang,Hye-Soon Lee,Kwangwoo Kim,Sang-Cheol Bae,Hong Zhang,Nan Shen,Loren L Looger,Swapan K Nath,Human molecular genetics,Oxford University Press (OUP),Vol. 26,No. 6,p. 1205-1216,2017年03月15日,研究論文(学術雑誌)
  • 痛風のゲノムワイド関連解析 新規遺伝座を含めた10個の痛風関連遺伝子座の同定,中山 昌喜,松尾 洋孝,崎山 真幸,高田 龍平,細山田 真,藤森 新,横尾 隆,細谷 龍男,大山 博司,清水 徹,市田 公美,四ノ宮 成祥,中岡 博史,山本 健,久保 充明,鎌谷 洋一郎,中村 好宏,Merriman Tony R.,豊田 優,鈴木 洋史,岡田 随象,若井 建志,日本痛風・核酸代謝学会総会プログラム抄録集,(一社)日本痛風・尿酸核酸学会,Vol. 50回,p. 127-127,2017年02月
  • Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.,van Rooij FJ,Qayyum R,Smith AV,Zhou Y,Trompet S,Tanaka T,Keller MF,Chang LC,Schmidt H,Yang ML,Chen MH,Hayes J,Johnson AD,Yanek LR,Mueller C,Lange L,Floyd JS,Ghanbari M,Zonderman AB,Jukema JW,Hofman A,van Duijn CM,Desch KC,Saba Y,Ozel AB,Snively BM,Wu JY,Schmidt R,Fornage M,Klein RJ,Fox CS,Matsuda K,Kamatani N,Wild PS,Stott DJ,Ford I,Slagboom PE,Yang J,Chu AY,Lambert AJ,Uitterlinden AG,Franco OH,Hofer E,Ginsburg D,Hu B,Keating B,Schick UM,Brody JA,Li JZ,Chen Z,Zeller T,Guralnik JM,Chasman DI,Peters LL,Kubo M,Becker DM,Li J,Eiriksdottir G,Rotter JI,Levy D,Grossmann V,Patel KV,Chen CH,BioBank Japan Project,Ridker PM,Tang H,Launer LJ,Rice KM,Li-Gao R,Ferrucci L,Evans MK,Choudhuri A,Trompouki E,Abraham BJ,Yang S,Takahashi A,Kamatani Y,Kooperberg C,Harris TB,Jee SH,Coresh J,Tsai FJ,Longo DL,Chen YT,Felix JF,Yang Q,Psaty BM,Boerwinkle E,Becker LC,Mook-Kanamori DO,Wilson JG,Gudnason V,O'Donnell CJ,Dehghan A,Cupples LA,Nalls MA,Morris AP,Okada Y,Reiner AP,Zon LI,Ganesh SK,American journal of human genetics,Elsevier BV,Vol. 100,No. 1,p. 51-63,2017年01月05日,研究論文(学術雑誌)
  • Dosage Contribution of a Non-Classical HLA Gene, HLA-Doa, to the Risk of Rheumatoid Arthritis,Okada Yukinori,Suzuki Akari,Ikari Katsunori,Terao Chikashi,Kochi Yuta,Ohmura Koichiro,Higasa Koichiro,Akiyama Masato,Ashikawa Kyoto,Kanai Masahiro,Hirata Jun,Suita Naomasa,Teo Yik-Ying,Xu Huji,Bae Sang-Cheol,Momozawa Yukihide,Matsuda Koichi,Momohara Shigeki,Taniguchi Atsuo,Yamada Ryo,Mimori Tsuneyo,Kubo Michiaki,Brown Matthew A,Raychaudhuri Soumya,Matsuda Fumihiko,Yamanaka Hisashi,Kamatani Yoichiro,Yamamoto Kazuhiko,ARTHRITIS & RHEUMATOLOGY,Vol. 68,2016年10月,研究論文(学術雑誌)
  • Combination of mouse models and genomewide association studies highlights novel genes associated with human kidney function.,Jing J,Pattaro C,Hoppmann A,Okada Y,CKDGen Consortium,Fox CS,Köttgen A,Kidney international,Elsevier BV,Vol. 90,No. 4,p. 764-73,2016年10月,研究論文(学術雑誌)
  • Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set.,Kanai M,Tanaka T,Okada Y,Journal of human genetics,Springer Science and Business Media LLC,Vol. 61,No. 10,p. 861-866,2016年10月,研究論文(学術雑誌)
  • Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study.,Li Z,Xia Y,Feng LN,Chen JR,Li HM,Cui J,Cai QQ,Sim KS,Nairismägi ML,Laurensia Y,Meah WY,Liu WS,Guo YM,Chen LZ,Feng QS,Pang CP,Chen LJ,Chew SH,Ebstein RP,Foo JN,Liu J,Ha J,Khoo LP,Chin ST,Zeng YX,Aung T,Chowbay B,Diong CP,Zhang F,Liu YH,Tang T,Tao M,Quek R,Mohamad F,Tan SY,Teh BT,Ng SB,Chng WJ,Ong CK,Okada Y,Raychaudhuri S,Lim ST,Tan W,Peng RJ,Khor CC,Bei JX,The Lancet. Oncology,Elsevier BV,Vol. 17,No. 9,p. 1240-7,2016年09月,研究論文(学術雑誌)
  • Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.,Mahajan A,Rodan AR,Le TH,Gaulton KJ,Haessler J,Stilp AM,Kamatani Y,Zhu G,Sofer T,Puri S,Schellinger JN,Chu PL,Cechova S,van Zuydam N,SUMMIT Consortium,BioBank Japan Project,Arnlov J,Flessner MF,Giedraitis V,Heath AC,Kubo M,Larsson A,Lindgren CM,Madden PA,Montgomery GW,Papanicolaou GJ,Reiner AP,Sundström J,Thornton TA,Lind L,Ingelsson E,Cai J,Martin NG,Kooperberg C,Matsuda K,Whitfield JB,Okada Y,Laurie CC,Morris AP,Franceschini N,American journal of human genetics,Elsevier BV,Vol. 99,No. 3,p. 636-646,2016年09月01日,研究論文(学術雑誌)
  • The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1.,Li G†,Cunin P,Wu D,Diogo D,Yang Y,Okada Y,Plenge RM,Nigrovic PA,PLoS genetics,Public Library of Science (PLoS),Vol. 12,No. 9,p. e1006292-e1006292,2016年09月,研究論文(学術雑誌)
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  • Systematic Comparison of Machine Learning Methods for Identification of miRNA Species as Disease Biomarkers,Chihiro Higuchi,Toshihiro Tanaka,Yukinori Okada,BIOINFORMATICS AND BIOMEDICAL ENGINEERING (IWBBIO 2015), PT II,SPRINGER INTERNATIONAL PUBLISHING AG,Vol. 9044,p. 386-394,2015年,研究論文(国際会議プロシーディングス)
  • TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.,Diogo D,Bastarache L,Liao KP,Graham RR,Fulton RS,Greenberg JD,Eyre S,Bowes J,Cui J,Lee A,Pappas DA,Kremer JM,Barton A,Coenen MJ,Franke B,Kiemeney LA,Mariette X,Richard-Miceli C,Canhão H,Fonseca JE,de Vries N,Tak PP,Crusius JB,Nurmohamed MT,Kurreeman F,Mikuls TR,Okada Y,Stahl EA,Larson DE,Deluca TL,O'Laughlin M,Fronick CC,Fulton LL,Kosoy R,Ransom M,Bhangale TR,Ortmann W,Cagan A,Gainer V,Karlson EW,Kohane I,Murphy SN,Martin J,Zhernakova A,Klareskog L,Padyukov L,Worthington J,Mardis ER,Seldin MF,Gregersen PK,Behrens T,Raychaudhuri S,Denny JC,Plenge RM,PloS one,PUBLIC LIBRARY SCIENCE,Vol. 10,No. 4,2015年,研究論文(学術雑誌)
  • Genetic studies of rheumatoid arthritis.,Kazuhiko Yamamoto,Yukinori Okada,Akari Suzuki,Yuta Kochi,Proceedings of the Japan Academy. Series B, Physical and biological sciences,JAPAN ACAD,Vol. 91,No. 8,p. 410-22,2015年,研究論文(学術雑誌)
  • The HLA-DRβ1 amino acid positions 11-13-26 explain the majority of SLE-MHC associations.,Kim K,Bang SY,Lee HS,Okada Y,Han B,Saw WY,Teo YY,Bae SC,Nature communications,Vol. 5,p. 5902-5902,2014年12月23日,研究論文(学術雑誌)
  • Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations.,Okada Y,Kim K,Han B,Pillai NE,Ong RT,Saw WY,Luo M,Jiang L,Yin J,Bang SY,Lee HS,Brown MA,Bae SC,Xu H,Teo YY,de Bakker PI,Raychaudhuri S,Human molecular genetics,Oxford University Press (OUP),Vol. 23,No. 25,p. 6916-26,2014年12月20日,研究論文(学術雑誌)
  • Trans-ethnic meta-analysis of white blood cell phenotypes.,Keller MF,Reiner AP,Okada Y,van Rooij FJ,Johnson AD,Chen MH,Smith AV,Morris AP,Tanaka T,Ferrucci L,Zonderman AB,Lettre G,Harris T,Garcia M,Bandinelli S,Qayyum R,Yanek LR,Becker DM,Becker LC,Kooperberg C,Keating B,Reis J,Tang H,Boerwinkle E,Kamatani Y,Matsuda K,Kamatani N,Nakamura Y,Kubo M,Liu S,Dehghan A,Felix JF,Hofman A,Uitterlinden AG,van Duijn CM,Franco OH,Longo DL,Singleton AB,Psaty BM,Evans MK,Cupples LA,Rotter JI,O'Donnell CJ,Takahashi A,Wilson JG,Ganesh SK,Nalls MA†,for the CHARGE Hematology,COGENT,BioBank Japan,Project (RIKEN,Working Groups,Human molecular genetics,OXFORD UNIV PRESS,Vol. 23,No. 25,p. 6944-60,2014年12月20日,研究論文(学術雑誌)
  • Variation at HLA-DRB1 is associated with resistance to enteric fever.,Dunstan SJ,Hue NT,Han B,Li Z,Tram TT,Sim KS,Parry CM,Chinh NT,Vinh H,Lan NP,Thieu NT,Vinh PV,Koirala S,Dongol S,Arjyal A,Karkey A,Shilpakar O,Dolecek C,Foo JN,Phuong le T,Lanh MN,Do T,Aung T,Hon do N,Teo YY,Hibberd ML,Anders KL,Okada Y,Raychaudhuri S,Simmons CP,Baker S,de Bakker PI,Basnyat B,Hien TT,Farrar JJ,Khor CC,Nature genetics,NATURE PUBLISHING GROUP,Vol. 46,No. 12,p. 1333-6,2014年12月,研究論文(学術雑誌)
  • A role for noncoding variation in schizophrenia.,Roussos P,Mitchell AC,Voloudakis G,Fullard JF,Pothula VM,Tsang J,Stahl EA,Georgakopoulos A,Ruderfer DM,Charney A,Okada Y,Siminovitch KA,Worthington J,Padyukov L,Klareskog L,Gregersen PK,Plenge RM,Raychaudhuri S,Fromer M,Purcell SM,Brennand KJ,Robakis NK,Schadt EE,Akbarian S,Sklar P,Cell reports,CELL PRESS,Vol. 9,No. 4,p. 1417-29,2014年11月20日,研究論文(学術雑誌)
  • From the era of genome analysis to the era of genomic drug discovery: a pioneering example of rheumatoid arthritis,Okada Y,Clinical Genetics,Wiley,Vol. 86,No. 5,p. 432-440,2014年11月,研究論文(学術雑誌)
  • Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.,Wen W,Zheng W,Okada Y,Takeuchi F,Tabara Y,Hwang JY,Dorajoo R,Li H,Tsai FJ,Yang X,He J,Wu Y,He M,Zhang Y,Liang J,Guo X,Sheu WH,Delahanty R,Guo X,Kubo M,Yamamoto K,Ohkubo T,Go MJ,Liu JJ,Gan W,Chen CC,Gao Y,Li S,Lee NR,Wu C,Zhou X,Song H,Yao J,Lee IT,Long J,Tsunoda T,Akiyama K,Takashima N,Cho YS,Ong RT,Lu L,Chen CH,Tan A,Rice TK,Adair LS,Gui L,Allison M,Lee WJ,Cai Q,Isomura M,Umemura S,Kim YJ,Seielstad M,Hixson J,Xiang YB,Isono M,Kim BJ,Sim X,Lu W,Nabika T,Lee J,Lim WY,Gao YT,Takayanagi R,Kang DH,Wong TY,Hsiung CA,Wu IC,Juang JM,Shi J,Choi BY,Aung T,Hu F,Kim MK,Lim WY,Wang TD,Shin MH,Lee J,Ji BT,Lee YH,Young TL,Shin DH,Chun BY,Cho MC,Han BG,Hwu CM,Assimes TL,Absher D,Yan X,Kim E,Kuo JZ,Kwon S,Taylor KD,Chen YD,Rotter JI,Qi L,Zhu D,Wu T,Mohlke KL,Gu D,Mo Z,Wu JY,Lin X,Miki T,Tai ES,Lee JY,Kato N,Shu XO†,Tanaka T,Human molecular genetics,OXFORD UNIV PRESS,Vol. 23,No. 20,p. 5492-504,2014年10月15日,研究論文(学術雑誌)
  • Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon.,Fukuda M,Mizutani T,Mochizuki W,Matsumoto T,Nozaki K,Sakamaki Y,Ichinose S,Okada Y,Tanaka T,Watanabe M,Nakamura T,Genes & development,Cold Spring Harbor Laboratory,Vol. 28,No. 16,p. 1752-7,2014年08月15日,研究論文(学術雑誌)
  • Predicting HLA alleles from high-resolution SNP data in three Southeast Asian populations.,Pillai NE,Okada Y,Saw WY,Ong RT,Wang X,Tantoso E,Xu W,Peterson TA,Bielawny T,Ali M,Tay KY,Poh WT,Tan LW,Koo SH,Lim WY,Soong R,Wenk M,Raychaudhuri S,Little P,Plummer FA,Lee EJ,Chia KS,Luo M,De Bakker PI,Teo YY,Human molecular genetics,OXFORD UNIV PRESS,Vol. 23,No. 16,p. 4443-51,2014年08月15日,研究論文(学術雑誌)
  • Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.,Okada Y,Han B,Tsoi LC,Stuart PE,Ellinghaus E,Tejasvi T,Chandran V,Pellett F,Pollock R,Bowcock AM,Krueger GG,Weichenthal M,Voorhees JJ,Rahman P,Gregersen PK,Franke A,Nair RP,Abecasis GR,Gladman DD,Elder JT,de Bakker PI,Raychaudhuri S,American journal of human genetics,Elsevier BV,Vol. 95,No. 2,p. 162-72,2014年08月07日,研究論文(学術雑誌)
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  • Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls,Liao KP,Diogo D,Cui J,Cai T,Okada Y,Gainer VS,Murphy SN,Gupta N,Mirel D,Ananthakrishnan AN,Szolovits P,Shaw SY,Raychaudhuri S,Churchill S,Kohane I,Karlson EW,Plenge RM,Annals of the Rheumatic Diseases,BMJ,Vol. 73,No. 6,p. 1170-1175,2014年06月,研究論文(学術雑誌)
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  • Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.,Han B,Diogo D,Eyre S,Kallberg H,Zhernakova A,Bowes J,Padyukov L,Okada Y,González-Gay MA,Rantapää-Dahlqvist S,Martin J,Huizinga TW,Plenge RM,Worthington J,Gregersen PK,Klareskog L,de Bakker PI,Raychaudhuri S,American journal of human genetics,CELL PRESS,Vol. 94,No. 4,p. 522-32,2014年04月03日,研究論文(学術雑誌)
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  • Genome-wide association studies to advance our understanding of critical cell types and pathways in rheumatoid arthritis: recent findings and challenges.,Diogo D,Okada Y,Plenge RM,Current opinion in rheumatology,LIPPINCOTT WILLIAMS & WILKINS,Vol. 26,No. 1,p. 85-92,2014年01月,研究論文(学術雑誌)
  • Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.,Okada Y,Diogo D,Greenberg JD,Mouassess F,Achkar WAL,Fulton RS,Denny JC,Gupta N,Mirel D,Gabriel S,Li G,Kremer JM,Pappas DA,Carroll RJ,Eyler AE,Trynka G,Stahl EA,Cui J,Saxena R,Coenen MJH,Guchelaar H,Huizinga TWJ,Dieudé P,Mariette X,Barton A,Canhão H,Fonseca JE,de Vries N,Tak PP,Moreland LW,Bridges Jr. SL,Miceli-Richard C,Choi HK,Kamatani Y,Galan P,Lathrop M,Raj T,De Jager PL,Raychaudhuri S,Worthington J,Padyukov L,Klareskog L,Siminovitch KA,Gregersen PK,Mardis ER,Arayssi T,Kazkaz LA,Plenge RM,PloS one,Public Library of Science (PLoS),Vol. 9,No. 2,p. e87645-e87645,2014年,研究論文(学術雑誌)
  • Editorial: entering the age of whole-exome sequencing in rheumatic diseases: novel insights into disease pathogenicity.,Okada Y,Plenge RM,Arthritis and rheumatism,Wiley,Vol. 65,No. 8,p. 1975-9,2013年08月,研究論文(学術雑誌)
  • An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.,Shimane K,Kochi Y,Suzuki A,Okada Y,Ishii T,Horita T,Saito K,Okamoto A,Nishimoto N,Myouzen K,Kubo M,Hirakata M,Sumida T,Takasaki Y,Yamada R,Nakamura Y,Kamatani N,Yamamoto K,Rheumatology (Oxford, England),OXFORD UNIV PRESS,Vol. 52,No. 7,p. 1172-82,2013年07月,研究論文(学術雑誌)
  • Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.,Chen Z,Tang H,Qayyum R,Schick UM,Nalls MA,Handsaker R,Li J,Lu Y,Yanek LR,Keating B,Meng Y,van Rooij FJ,Okada Y,Kubo M,Rasmussen-Torvik L,Keller MF,Lange L,Evans M,Bottinger EP,Linderman MD,Ruderfer DM,Hakonarson H,Papanicolaou G,Zonderman AB,Gottesman O,BioBank Japan Project,CHARGE Consortium,Thomson C,Ziv E,Singleton AB,Loos RJ,Sleiman PM,Ganesh S,McCarroll S,Becker DM,Wilson JG,Lettre G,Reiner AP,Human molecular genetics,OXFORD UNIV PRESS,Vol. 22,No. 12,p. 2529-38,2013年06月15日,研究論文(学術雑誌)
  • Seven new loci associated with age-related macular degeneration.,Fritsche LG,Chen W,Schu M,Yaspan BL,Yu Y,Thorleifsson G,Zack DJ,Arakawa S,Cipriani V,Ripke S,Igo RP Jr,Buitendijk GH,Sim X,Weeks DE,Guymer RH,Merriam JE,Francis PJ,Hannum G,Agarwal A,Armbrecht AM,Audo I,Aung T,Barile GR,Benchaboune M,Bird AC,Bishop PN,Branham KE,Brooks M,Brucker AJ,Cade WH,Cain MS,Campochiaro PA,Chan CC,Cheng CY,Chew EY,Chin KA,Chowers I,Clayton DG,Cojocaru R,Conley YP,Cornes BK,Daly MJ,Dhillon B,Edwards AO,Evangelou E,Fagerness J,Ferreyra HA,Friedman JS,Geirsdottir A,George RJ,Gieger C,Gupta N,Hagstrom SA,Harding SP,Haritoglou C,Heckenlively JR,Holz FG,Hughes G,Ioannidis JP,Ishibashi T,Joseph P,Jun G,Kamatani Y,Katsanis N,N Keilhauer C,Khan JC,Kim IK,Kiyohara Y,Klein BE,Klein R,Kovach JL,Kozak I,Lee CJ,Lee KE,Lichtner P,Lotery AJ,Meitinger T,Mitchell P, Moha,d-Saïd S,Moore AT,Morgan DJ,Morrison MA,Myers CE,Naj AC,Nakamura Y,Okada Y,Orlin A,Ortube MC,Othman MI,Pappas C,Park KH,Pauer GJ,Peachey NS,Poch O,Priya RR,Reynolds R,Richardson AJ,Ripp R,Rudolph G,Ryu E,Sahel JA,Schaumberg DA,Scholl HP,Schwartz SG,Scott WK,Shahid H,Sigurdsson H,Silvestri G,Sivakumaran TA,Smith RT,Sobrin L,Souied EH,Stambolian DE,Stefansson H,Sturgill-Short GM,Takahashi A,Tosakulwong N,Truitt BJ,Tsironi EE,Uitterlinden AG,van Duijn CM,Vijaya L,Vingerling JR,Vithana EN,Webster AR,Wichmann HE,Winkler TW,Wong TY,Wright AF,Zelenika D,Zhang M,Zhao L,Zhang K,Klein ML,Hageman GS,Lathrop GM,Stefansson K,Allikmets R,Baird PN,Gorin MB,Wang JJ,Klaver CC,Seddon JM,Pericak-Vance MA,Iyengar SK,Yates JR,Swaroop A,Weber BH,Kubo M,Deangelis MM,Léveillard T,Thorsteinsdottir U,Haines JL,Farrer LA†,Heid IM,Abecasis GR,AMD Gene Consortium,Nature genetics,NATURE PUBLISHING GROUP,Vol. 45,No. 4,p. 433-9,2013年04月,研究論文(学術雑誌)
  • Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis,Cui J,Stahl EA,Saevarsdottir S,Miceli C,Diogo D,Trynka G,Raj T,Mirkov MU,Canhao H,Ikari K,Terao C,Okada Y,Wedrén S,Askling J,Yamanaka H,Momohara S,Taniguchi A,Ohmura K,Matsuda F,Mimori T,Gupta N,Kuchroo M,Morgan AW,Isaacs JD,Wilson AG,Hyrich KL,Herenius M,Doorenspleet ME,Tak PP,Crusius JB,van der Horst-Bruinsma IE,Wolbink GJ,van Riel PL,van de Laar M,Guchelaar HJ,Shadick NA,Allaart CF,Huizinga TW,Toes RE,Kimberly RP,Bridges SL Jr,Criswell LA,Moreland LW,Fonseca JE,de Vries N,Stranger BE,De Jager PL,Raychaudhuri S,Weinblatt ME,Gregersen PK,Mariette X,Barton A,Padyukov L,Coenen MJ,Karlson EW,Plenge RM,PLoS Genetics,Public Library of Science (PLoS),Vol. 9,No. 3,p. e1003394-e1003394,2013年03月28日,研究論文(学術雑誌)
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  • Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.,Dunlop MG,Dobbins SE,Farrington SM,Jones AM,Palles C,Whiffin N,Tenesa A,Spain S,Broderick P,Ooi LY,Domingo E,Smillie C,Henrion M,Frampton M,Martin L,Grimes G,Gorman M,Semple C,Ma YP,Barclay E,Prendergast J,Cazier JB,Olver B,Penegar S,Lubbe S,Chander I,Carvajal-Carmona LG,Ballereau S,Lloyd A,Vijayakrishnan J,Zgaga L,Rudan I,Theodoratou E,Colorectal Tumour,Gene Identification,CORGI) Consortium,Starr JM,Deary I,Kirac I,Kovacević D,Aaltonen LA,Renkonen-Sinisalo L,Mecklin JP,Matsuda K,Nakamura Y,Okada Y,Gallinger S,Duggan DJ,Conti D,Newcomb P,Hopper J,Jenkins MA,Schumacher F,Casey G,Easton D,Shah M,Pharoah P,Lindblom A,Liu T,Swedish Low-Risk Colorectal Cancer,Study Group,Smith CG,West H,Cheadle JP,COIN Collaborative Group,Midgley R,Kerr DJ,Campbell H,Tomlinson IP,Houlston RS,Nature genetics,NATURE PUBLISHING GROUP,Vol. 44,No. 7,p. 770-6,2012年05月27日,研究論文(学術雑誌)
  • Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.,Okada Y,Terao C,Ikari K,Kochi Y,Ohmura K,Suzuki A,Kawaguchi T,Stahl EA,Kurreeman FA,Nishida N,Ohmiya H,Myouzen K,Takahashi M,Sawada T,Nishioka Y,Yukioka M,Matsubara T,Wakitani S,Teshima R,Tohma S,Takasugi K,Shimada K,Murasawa A,Honjo S,Matsuo K,Tanaka H,Tajima K,Suzuki T,Iwamoto T,Kawamura Y,Tanii H,Okazaki Y,Sasaki T,Gregersen PK,Padyukov L,Worthington J,Siminovitch KA,Lathrop M,Taniguchi A,Takahashi A,Tokunaga K,Kubo M,Nakamura Y,Kamatani N,Mimori T,Plenge RM,Yamanaka H,Momohara S,Yamada R,Matsuda F,Yamamoto K,Nature genetics,Springer Science and Business Media LLC,Vol. 44,No. 5,p. 511-6,2012年03月25日,研究論文(学術雑誌)
  • Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12.,Kurreeman FA,Stahl EA,Okada Y,Liao K,Diogo D,Raychaudhuri S,Freudenberg J,Kochi Y,Patsopoulos NA,Gupta N,CLEAR investigators,Sandor C,Bang SY,Lee HS,Padyukov L,Suzuki A,Siminovitch K,Worthington J,Gregersen PK,Hughes LB,Reynolds RJ,Bridges SL Jr,Bae SC,Yamamoto K,Plenge RM,American journal of human genetics,CELL PRESS,Vol. 90,No. 3,p. 524-32,2012年03月09日,研究論文(学術雑誌)
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  • Common genetic factors for hematological traits in humans.,Okada Y,Kamatani Y,Journal of human genetics,NATURE PUBLISHING GROUP,Vol. 57,No. 3,p. 161-9,2012年03月,研究論文(学術雑誌)
  • Meta-analysis identifies common variants associated with body mass index in east Asians,Wen W,Cho YS,Zheng W,Dorajoo R,Kato N,Qi L,Chen CH,Delahanty RJ,Okada Y,Tabara Y,Gu D,Zhu D,Haiman CA,Mo Z,Gao YT,Saw SM,Go MJ,Takeuchi F,Chang LC,Kokubo Y,Liang J,Hao M,Le Marchand L,Zhang Y,Hu Y,Wong TY,Long J,Han BG,Kubo M,Yamamoto K,Su MH,Miki T,Henderson BE,Song H,Tan A,He J,Ng DP,Cai Q,Tsunoda T,Tsai FJ,Iwai N,Chen GK,Shi J,Xu J,Sim X,Xiang YB,Maeda S,Ong RT,Li C,Nakamura Y,Aung T,Kamatani N,Liu JJ,Lu W,Yokota M,Seielstad M,Fann CS,Genetic Investigation of,ANthropometric Traits,GIANT) Consortium,Wu JY,Lee JY,Hu FB,Tanaka T,Tai ES,Shu XO,Nature Genetics,Springer Science and Business Media LLC,Vol. 44,No. 3,p. 307-311,2012年03月,研究論文(学術雑誌)
  • Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.,Okada Y,Kubo M,Ohmiya H,Takahashi A,Kumasaka N,Hosono N,Maeda S,Wen W,Dorajoo R,Go MJ,Zheng W,Kato N,Wu JY,Lu Q,GIANT consortium,Tsunoda T,Yamamoto K,Nakamura Y,Kamatani N,Tanaka T,Nature genetics,Springer Science and Business Media LLC,Vol. 44,No. 3,p. 302-6,2012年02月19日,研究論文(学術雑誌)
  • A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese,Okada Y,Shimane K,Kochi Y,Tahira T,Suzuki A,Higasa K,Takahashi A,Horita T,Atsumi T,Ishii T,Okamoto A,Fujio K,Hirakata M,Amano H,Kondo Y,Ito S,Takada K,Mimori A,Saito K,Kamachi M,Kawaguchi Y,Ikari K,Mohammed OW,Matsuda K,Terao C,Ohmura K,Myouzen K,Hosono N,Tsunoda T,Nishimoto N,Mimori T,Matsuda F,Tanaka Y,Sumida T,Yamanaka H,Takasaki Y,Koike T,Horiuchi T,Hayashi K,Kubo M,Kamatani N,Yamada R,Nakamura Y,Yamamoto K,PLoS Genetics,Public Library of Science (PLoS),Vol. 8,No. 1,p. e1002455-e1002455,2012年01月26日,研究論文(学術雑誌)
  • A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.,Urabe Y,Tanikawa C,Takahashi A,Okada Y,Morizono T,Tsunoda T,Kamatani N,Kohri K,Chayama K,Kubo M,Nakamura Y,Matsuda K,PLoS genetics,Vol. 8,No. 3,2012年,研究論文(学術雑誌)
  • Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.,Osman W,Okada Y,Kamatani Y,Kubo M,Matsuda K,Nakamura Y,PloS one,PUBLIC LIBRARY SCIENCE,Vol. 7,No. 4,2012年,研究論文(学術雑誌)
  • Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.,Kumasaka N,Aoki M,Okada Y,Takahashi A,Ozaki K,Mushiroda T,Hirota T,Tamari M,Tanaka T,Nakamura Y,Kamatani N,Kubo M,PloS one,PUBLIC LIBRARY SCIENCE,Vol. 7,No. 9,2012年,研究論文(学術雑誌)
  • Insight from genome-wide association studies in rheumatoid arthritis and multiple sclerosis,Suzuki A,Kochi Y,Okada Y,Yamamoto K,FEBS Letters,Wiley,Vol. 585,No. 23,p. 3627-3632,2011年12月01日,研究論文(学術雑誌)
  • PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.,Kumasaka N,Fujisawa H,Hosono N,Okada Y,Takahashi A,Nakamura Y,Kubo M,Kamatani N,Genetic epidemiology,WILEY-BLACKWELL,Vol. 35,No. 8,p. 831-44,2011年12月,研究論文(学術雑誌)
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  • HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis but Reduces Risk for Crohn's Disease,Okada Y,Yamazaki K,Umeno J,Takahashi A,Kumasaka N,Ashikawa K,Aoi T,Takazoe M,Matsui T,Hirano A,Matsumoto T,Kamatani N,Nakamura Y,Yamamoto K,Kubo M,Gastroenterology,Elsevier BV,Vol. 141,No. 3,p. 864-871.e5,2011年09月,研究論文(学術雑誌)
  • The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population,Terao C,Yamada R,Ohmura K,Takahashi M,Kawaguchi T,Kochi Y,Human Disease,Genomics Working Group,RA Clinical,Genetic Study Consortium,Okada Y,Nakamura Y,Yamamoto K,Melchers I,Lathrop M,Mimori T,Matsuda F,Human Molecular Genetics,Oxford University Press (OUP),Vol. 20,No. 13,p. 2680-2685,2011年07月01日,研究論文(学術雑誌)
  • Identification of Nine Novel Loci Associated with White Blood Cell Subtypes in a Japanese Population,Okada Y,Hirota T,Kamatani Y,Takahashi A,Ohmiya H,Kumasaka N,Higasa K,Yamaguchi-Kabata Y,Hosono N,Nalls MA,Chen MH,van Rooij FJ,Smith AV,Tanaka T,Couper DJ,Zakai NA,Ferrucci L,Longo DL,Hernandez DG,Witteman JC,Harris TB,O'Donnell CJ,Ganesh SK,Matsuda K,Tsunoda T,Tanaka T,Kubo M,Nakamura Y,Tamari M,Yamamoto K,Kamatani N,PLoS Genetics,Public Library of Science (PLoS),Vol. 7,No. 6,p. e1002067-e1002067,2011年06月30日,研究論文(学術雑誌)
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  • Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population,R. Cui,Y. Okada,S. G. Jang,J. L. Ku,J. G. Park,Y. Kamatani,N. Hosono,T. Tsunoda,V. Kumar,C. Tanikawa,N. Kamatani,R. Yamada,M. Kubo,Y. Nakamura,K. Matsuda,Gut,BMJ,Vol. 60,No. 6,p. 799-805,2011年06月01日,研究論文(学術雑誌)
  • Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus,Okada Y,Takahashi A,Ohmiya H,Kumasaka N,Kamatani Y,Hosono N,Tsunoda T,Matsuda K,Tanaka T,Kubo M,Nakamura Y,Yamamoto K,Kamatani N,Human Molecular Genetics,Oxford University Press (OUP),Vol. 20,No. 6,p. 1224-1231,2011年03月15日,研究論文(学術雑誌)
  • PADI4 polymorphism predisposes male smokers to rheumatoid arthritis,Kochi Y,Thabet MM,Suzuki A,Okada Y,Daha NA,Toes RE,Huizinga TW,Myouzen K,Kubo M,Yamada R,Nakamura Y,Yamamoto K,Annals of the Rheumatic Diseases,BMJ,Vol. 70,No. 3,p. 512-515,2011年03月,研究論文(学術雑誌)
  • Tacrolimus and steroid treatment for acute exacerbation of idiopathic pulmonary fibrosis.,Nobuyuki Horita,Makiko Akahane,Yukinori Okada,Yosuke Kobayashi,Takahiko Arai,Izuki Amano,Tomoko Takezawa,Masako To,Yasuo To,Internal medicine (Tokyo, Japan),JAPAN SOC INTERNAL MEDICINE,Vol. 50,No. 3,p. 189-95,2011年,研究論文(学術雑誌)
  • Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.,Ayaka Koike,Hiroyuki Nishikawa,Wenwen Wu,Yukinori Okada,Ashok R Venkitaraman,Tomohiko Ohta,Cancer research,AMER ASSOC CANCER RESEARCH,Vol. 70,No. 17,p. 6746-56,2010年09月01日,研究論文(学術雑誌)
  • HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis,Y. Okada,A. Suzuki,R. Yamada,Y. Kochi,K. Shimane,K. Myouzen,M. Kubo,Y. Nakamura,K. Yamamoto,Annals of the Rheumatic Diseases,BMJ,Vol. 69,No. 8,p. 1569-1570,2010年08月01日,研究論文(学術雑誌)
  • A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci,Okada Y,Kamatani Y,Takahashi A,Matsuda K,Hosono N,Ohmiya H,Daigo Y,Yamamoto K,Kubo M,Nakamura Y,Kamatani N,Human Molecular Genetics,Oxford University Press (OUP),Vol. 19,No. 11,p. 2303-2312,2010年06月01日,研究論文(学術雑誌)
  • Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus,Myouzen K,Kochi Y,Shimane K,Fujio K,Okamura T,Okada Y,Suzuki A,Atsumi T,Ito S,Takada K,Mimori A,Ikegawa S,Yamada R,Nakamura Y,Yamamoto K,Human Molecular Genetics,Oxford University Press (OUP),Vol. 19,No. 11,p. 2313-2320,2010年06月01日,研究論文(学術雑誌)
  • A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility,Kochi Y,Okada Y,Suzuki A,Ikari K,Terao C,Takahashi A,Yamazaki K,Hosono N,Myouzen K,Tsunoda T,Kamatani N,Furuichi T,Ikegawa S,Ohmura K,Mimori T,Matsuda F,Iwamoto T,Momohara S,Yamanaka H,Yamada R,Kubo M,Nakamura Y,Yamamoto K,Nature Genetics,Springer Science and Business Media LLC,Vol. 42,No. 6,p. 515-519,2010年06月,研究論文(学術雑誌)
  • Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.,Okada Y,Kamatani Y,Takahashi A,Matsuda K,Hosono N,Ohmiya H,Daigo Y,Yamamoto K,Kubo M,Nakamura Y,Kamatani N,Human molecular genetics,OXFORD UNIV PRESS,Vol. 19,No. 10,p. 2079-85,2010年05月15日,研究論文(学術雑誌)
  • Genome-wide association study of hematological and biochemical traits in a Japanese population,Kamatani Y,Matsuda K,Okada Y,Kubo M,Hosono N,Daigo Y,Nakamura Y,Kamatani N,Nature Genetics,Springer Science and Business Media LLC,Vol. 42,No. 3,p. 210-215,2010年03月,研究論文(学術雑誌)
  • Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1,Okada Y,Yamada R,Suzuki A,Kochi Y,Shimane K,Myouzen K,Kubo M,Nakamura Y,Yamamoto K,Arthritis & Rheumatism,Wiley,Vol. 60,No. 12,p. 3582-3590,2009年12月,研究論文(学術雑誌)
  • A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population,K Shimane,Y Kochi,R Yamada,Y Okada,A Suzuki,A Miyatake,M Kubo,Y Nakamura,K Yamamoto,Annals of the Rheumatic Diseases,BMJ,Vol. 68,No. 3,p. 377-383,2009年03月,研究論文(学術雑誌)
  • An optimal dose-effect mode trend test for SNP genotype tables,Yamada R,Okada Y,Genetic Epidemiology,Wiley,Vol. 33,No. 2,p. 114-127,2009年02月,研究論文(学術雑誌)
  • Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.,Suzuki A,Yamada R,Kochi Y,Sawada T,Okada Y,Matsuda K,Kamatani Y,Mori M,Shimane K,Hirabayashi Y,Takahashi A,Tsunoda T,Miyatake A,Kubo M,Kamatani N,Nakamura Y,Yamamoto K,Nature genetics,NATURE PUBLISHING GROUP,Vol. 40,No. 10,p. 1224-1229,2008年10月,研究論文(学術雑誌)
  • SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis,Okada Y,Mori M,Yamada R,Suzuki A,Kobayashi K,Kubo M,Nakamura Y,Yamamoto K,The Journal of Rheumatology,Vol. 35,p. 1723-1728,2008年09月,研究論文(学術雑誌)
  • Unified model of association-induced lower critical solution temperature phase separation and its application to solutions of telechelic poly(ethylene oxide) and of telechelic poly(N-isopropylacrylamide) in water,Okada Y,Tanaka F,Piotr Kujawa,Françoise M. Winnik,The Journal of Chemical Physics,AIP Publishing,Vol. 125,No. 24,p. 244902-244902,2006年12月28日,研究論文(学術雑誌)
  • The longitudinal effects of the "Green Revolution" on the infant mortality rate in rural Thailand,Okada Y,Wakai S,Japan Medical Association Journal,Vol. 49,p. 236-242,2006年

MISC

  • 免疫疾患の遺伝素因,山本 賢一,岡田 随象,医学のあゆみ 難治性免疫疾患,Vol. 277,No. 9,p. 648-653,2021年05月,記事・総説・解説・論説等(学術雑誌)
  • 呼吸器疾患におけるゲノムワイド関連解析(GWAS),白井 雄也,岡田 随象,BioClinica,Vol. 36,No. 5,p. 403-407,2021年05月,記事・総説・解説・論説等(学術雑誌)
  • 大規模疾患ゲノム解析の今後,岡田 随象,BIO Clinica,Vol. 36,p. 396-397,2021年05月,記事・総説・解説・論説等(学術雑誌)
  • 大規模データからのGWAS、その他の解析の最新事情,内藤 龍彦,岡田 随象,実験医学増刊,Vol. 39,No. 7,2021年05月,記事・総説・解説・論説等(学術雑誌)
  • Polygenic risk scoreを活用したゲノム個別化医療,岡田 随象,日本内科学会雑誌,Vol. 110,No. 3,p. 400-406,2021年03月,記事・総説・解説・論説等(学術雑誌)
  • 機械学習と次世代シークエンス技術の活用による白血球の血液型の解明,平田 潤,岡田 随象,感染・炎症・免疫,Vol. 144,p. 20-25,2021年,記事・総説・解説・論説等(学術雑誌)
  • 感染症領域におけるゲノムワイド関連解析(GWAS),枝廣龍哉,岡田随象,実験医学増刊,Vol. 39,No. 2,p. 286-292,2021年01月,記事・総説・解説・論説等(学術雑誌)
  • 関節リウマチと腸内微生物叢,岸川 敏弘,岡田 随象,診断と治療社,p. 39-44,2021年01月,記事・総説・解説・論説等(学術雑誌)
  • GWASから膠原病を見える化する,友藤 嘉彦,岡田 随象,medicina,Vol. 57,No. 12,p. 2177-2181,2020年11月
  • ゲノム情報を活用したバイオマーカーの同定とゲノム創薬,難波 真一,岡田 随象,アレルギー,Vol. 69,No. 10,p. 952-957,2020年10月
  • 遺伝統計学とゲノム創薬,小沼 貴裕,岡田 随象,臨床免疫・アレルギー科,Vol. 74,No. 4,p. 381-384,2020年10月,記事・総説・解説・論説等(学術雑誌)
  • 【自己免疫疾患】横断的オミクス解析による自己免疫疾患の病態解明とゲノム創薬,田中 宏明,岡田 随象,別冊Bio Clinica: 慢性炎症と疾患,(株)北隆館,Vol. 9,No. 1,p. 44-49,2020年08月,記事・総説・解説・論説等(学術雑誌)
  • 腸内微生物の全ゲノム解析からみた関節リウマチの病因,岸川 敏博,岡田 随象,リウマチ科,(有)科学評論社,Vol. 64,No. 2,p. 208-215,2020年08月,記事・総説・解説・論説等(学術雑誌)
  • 一卵性双生児を対象とした日本人GWASによる臨床検査値予測モデルの検証,谷口 純平,渡邉 幹夫,増田 達郎,岩谷 良則,岡田 随象,大阪ツインリサーチグループ,臨床化学,(一社)日本臨床化学会,Vol. 49,No. 3,p. 217-219,2020年07月
  • 遺伝統計学で迫る疾患病態解明とゲノム創薬,増田 達郎,岡田 随象,日本エンドメトリオーシス学会会誌,日本エンドメトリオーシス学会,Vol. 41,p. 50-55,2020年07月,記事・総説・解説・論説等(学術雑誌)
  • 脳神経外科と数理学 脳神経外科領域におけるゲノムワイド関連解析(GWAS),白井 雄也,岡田 随象,Neurological Surgery,(株)医学書院,Vol. 48,No. 6,p. 561-570,2020年06月
  • 遺伝統計学で迫る皮膚科疾患の病態解明とゲノム創薬,岡田 随象,西日本皮膚科,日本皮膚科学会-西部支部,Vol. 82,No. 3,p. 201-201,2020年06月
  • 脳神経外科と数理学 脳神経外科領域におけるゲノムワイド関連解析(GWAS),白井 雄也,岡田 随象,Neurological Surgery,(株)医学書院,Vol. 48,No. 6,p. 561-570,2020年06月,記事・総説・解説・論説等(学術雑誌)
  • 遺伝統計学による関節リウマチのゲノム個別化医療,岸川 敏博,岡田 随象,関節リウマチ,Vol. 32,No. 4,p. 310-317,2020年04月,記事・総説・解説・論説等(学術雑誌)
  • 【GWASで複雑形質を解くぞ!多因子疾患・形質のバイオロジーに挑む次世代のゲノム医科学】GWASからマイクロRNAの複雑形質への関与の解明に挑む,坂上 沙央里,岡田 随象,実験医学,(株)羊土社,Vol. 38,No. 4,p. 544-549,2020年03月,記事・総説・解説・論説等(学術雑誌)
  • 神経疾患と慢性炎症 10 脳神経疾患における遺伝統計解析,小河浩太郎,岡田随象,Bio Clinica,2020年
  • ゲノムワイド関連解析の解析手法,増田 達郎,岡田 随象,遺伝子医学,(株)メディカルドゥ,Vol. 10,No. 1,p. 117-123,2020年01月
  • 遺伝統計学の活用による核酸ゲノム創薬,坂上 沙央里,岡田 随象,日本内科学会雑誌,(一社)日本内科学会,Vol. 109,No. 1,p. 107-112,2020年01月
  • 無症候性高尿酸血症から痛風発作を引き起こす新規遺伝子座を同定した,青木 優佳,河村 優輔,中岡 博史,中山 昌喜,岡田 随象,山本 健,東野 俊英,崎山 真幸,清水 聖子,川口 真,高尾 幹也,前原 一輝,中蔦 真由子,四ノ宮 成祥,松尾 洋孝,防衛衛生,(一社)日本防衛衛生学会,Vol. 67,No. 別冊,p. 63-63,2019年12月
  • 大規模ヒトゲノム解析による日本人集団の適応進化の解明,安水 良明,岡田 随象,腎臓内科・泌尿器科,(有)科学評論社,Vol. 10,No. 6,p. 566-571,2019年12月
  • 免疫アレルギー疾患とNon-coding RNA,岡田 随象,アレルギー,(一社)日本アレルギー学会,Vol. 68,No. 10,p. 1196-1199,2019年12月
  • 機械学習と次世代シークエンス技術の活用による白血球の血液型の解明,平田 潤,岡田 随象,内分泌・糖尿病・代謝内科,(有)科学評論社,Vol. 49,No. 5,p. 385-389,2019年11月
  • 【糖尿病・肥満症に対するPrecision Medicine実現に向けて】パスウェイ解析を用いた2型糖尿病遺伝素因の日欧の比較,細江 隼,鈴木 顕,加藤 貴史,岡田 随象,庄嶋 伸浩,山内 敏正,門脇 孝,内分泌・糖尿病・代謝内科,(有)科学評論社,Vol. 49,No. 5,p. 337-342,2019年11月
  • ゲノム医療 PRSが変える日本の精神医療,岩田 仲生,鎌谷 洋一郎,岡田 随象,池田 匡志,精神科臨床Legato,(株)メディカルレビュー社,Vol. 5,No. 3,p. 120-127,2019年11月
  • 大規模ゲノム解析による28の新規2型糖尿病感受性領域の同定,鈴木 顕,秋山 雅人,石垣 和慶,金井 仁弘,細江 隼,庄嶋 伸浩,池川 志郎,寳澤 篤,山本 雅之,門田 文,栗木 清典,内藤 真理子,若井 建志,丹野 高三,石垣 泰,佐々木 真理,平田 真,松田 浩一,村上 善則,岩田 仲生,池田 匡志,澤田 典絵,山地 太樹,岩崎 基,津金 昌一郎,前田 士郎,岡田 随象,久保 充明,鎌谷 洋一郎,堀越 桃子,山内 敏正,門脇 孝,肥満研究,(一社)日本肥満学会,Vol. 25,No. Suppl.,p. 246-246,2019年10月
  • 【HLAと疾患感受性 自己免疫・アレルギー疾患やがんにおける"自己"の役割】遺伝統計解析によるHLA遺伝子の疾患発症メカニズムの解明,平田 潤,岡田 随象,実験医学,(株)羊土社,Vol. 37,No. 14,p. 2265-2269,2019年09月
  • NGSを用いたHLA分析から明らかになった日本のMSおよびNMOSDに関する免疫学的背景(NGS-based HLA analysis identified the immunological background of MS and NMOSD in Japanese),小河 浩太郎,奥野 龍禎,細道 一善,木下 允,細川 明子,宮本 勝一,井ノ上 逸朗,楠 進,岡田 随象,望月 秀樹,神経免疫学,日本神経免疫学会,Vol. 24,No. 1,p. 95-95,2019年09月
  • 【システム臨床免疫学】疾患感受性遺伝子の探索と疾患発症メカニズムの解明,平田 潤,岡田 随象,炎症と免疫,(株)先端医学社,Vol. 27,No. 5,p. 393-397,2019年08月
  • 全ゲノムシークエンスが明らかにした日本人集団の適応進化とアルコール代謝の関わり,岡田 随象,日本アルコール・薬物医学会雑誌,(一社)日本アルコール・アディクション医学会,Vol. 54,No. 4,p. 95-95,2019年08月
  • 一卵性双生児を対象とした日本人GWASによる臨床検査値予測モデルの検証,谷口 純平,渡邉 幹夫,増田 達郎,岩谷 良則,岡田 随象,大阪ツインリサーチグループ,臨床化学,(一社)日本臨床化学会,Vol. 48,No. Suppl.1,p. 191-191,2019年08月
  • 無症候性高尿酸血症群と痛風症例群のゲノムワイド関連解析により痛風発症に関連する新規遺伝子座を同定した,河村 優輔,松尾 洋孝,中山 昌喜,東野 俊英,清水 徹,大山 博司,大山 恵子,長瀬 満夫,清水 聖子,川口 真,高尾 幹也,高田 龍平,細谷 龍男,市田 公美,四ノ宮 成祥,中岡 博史,岡田 随象,山本 健,崎山 真幸,中村 好宏,鎌谷 洋一郎,久保 充明,井ノ上 逸朗,痛風と尿酸・核酸,(一社)日本痛風・尿酸核酸学会,Vol. 43,No. 1,p. 29-30,2019年07月
  • 日本人121,745人を対象としたゲノムワイドメタ解析により血清尿酸値と関連する8つの新規遺伝子座を同定した,中杤 昌弘,松尾 洋孝,中山 昌喜,河村 優輔,清水 聖子,川口 真,高尾 幹也,四ノ宮 成祥,金井 仁弘,菱田 朝陽,中村 好宏,久保 充明,鎌谷 洋一郎,横田 充弘,若井 建志,岡田 随象,痛風と尿酸・核酸,(一社)日本痛風・尿酸核酸学会,Vol. 43,No. 1,p. 31-31,2019年07月
  • リウマチ性疾患におけるオミクス解析とゲノム創薬,田中 宏明,岡田 随象,リウマチ科,(有)科学評論社,Vol. 62,No. 1,p. 108-114,2019年07月,記事・総説・解説・論説等(学術雑誌)
  • 遺伝統計学で迫る日本人集団の適応進化,岡田 随象,学士会会報,学士会,Vol. 2019,No. 3,p. 67-76,2019年05月
  • 横断的オミクス解析による疾患病態解明とゲノム創薬,岡田 随象,肺癌,(NPO)日本肺癌学会,Vol. 59,No. 2,p. 212-213,2019年04月
  • 遺伝統計学で迫る皮膚疾患,岡田 随象,日本皮膚科学会雑誌,(公社)日本皮膚科学会,Vol. 129,No. 4,p. 574-575,2019年04月
  • バイオインフォマティクスによるゲノム創薬,岡田 随象,日本医学会総会会誌,日本医学会,Vol. 30回,p. 柱1-3,2019年04月
  • 横断的オミクス解析で迫る疾患病態解明とゲノム創薬,岡田 随象,日本内分泌学会雑誌,(一社)日本内分泌学会,Vol. 95,No. 1,p. 320-320,2019年04月
  • 大規模ゲノム解析による28の新規2型糖尿病感受性領域および日本人と欧米人に特徴的な2型糖尿病の生物学的パスウェイの同定,鈴木 顕,秋山 雅人,石垣 和慶,金井 仁弘,細江 隼,庄嶋 伸浩,久保 充明,岡田 随象,鎌谷 洋一郎,堀越 桃子,山内 敏正,門脇 孝,日本臨床分子医学会学術総会プログラム・抄録集,日本臨床分子医学会,Vol. 56回,p. 46-46,2019年04月
  • メガゲノム時代の糖尿病学 横断的オミクス解析で迫る疾患病態解明とゲノム創薬,岡田 随象,糖尿病,(一社)日本糖尿病学会,Vol. 62,No. Suppl.1,p. S-62,2019年04月
  • 大規模ゲノム解析による28の新規2型糖尿病感受性領域および日本人と欧米人に特徴的な2型糖尿病の生物学的パスウェイの同定,鈴木 顕,秋山 雅人,石垣 和慶,金井 仁弘,細江 隼,庄嶋 伸浩,岩田 仲生,池田 匡志,池川 志郎,前田 士郎,村上 善則,若井 建志,津金 昌一郎,佐々木 真理,山本 雅之,岡田 随象,久保 充明,鎌谷 洋一郎,堀越 桃子,山内 敏正,門脇 孝,糖尿病,(一社)日本糖尿病学会,Vol. 62,No. Suppl.1,p. S-108,2019年04月
  • 微生物ゲノムと宿主ゲノムの相互連関 遺伝統計学で紐解くヒトゲノムとメタゲノムの関わり,岡田 随象,日本細菌学雑誌,日本細菌学会,Vol. 74,No. 1,p. 13-13,2019年03月
  • 特集 : バイオインフォマティクスの進展・臨床応用 序論,岡田随象,最新医学,Vol. 74,No. 2,p. 169-170,2019年02月
  • 【バイオインフォマティクスの進展・臨床応用】バイオインフォマティクスを使い倒すために必要なこと,細道 一善,秋山 雅人,岡田 随象,最新医学,(株)最新医学社,Vol. 74,No. 2,p. 171-184,2019年02月
  • 日本人の臨床検査値に影響する遺伝的背景の解明 58の量的形質における大規模ゲノムワイド関連解析,金井 仁弘,岡田 随象,鎌谷 洋一郎,臨床免疫・アレルギー科,(有)科学評論社,Vol. 71,No. 1,p. 78-85,2019年01月
  • 侵襲性歯周炎における遺伝子変異の同定,須藤 毅顕,岡田 随象,尾崎 浩一,浦山 ケビン,金井 仁弘,小林 宏明,御給 美沙,和泉 雄一,田中 敏博,歯界展望,医歯薬出版(株),Vol. 132,No. 6,p. 1101-1104,2018年12月
  • 日本人における尿酸値のGWASメタ解析による8個の新規遺伝子座の同定,中嶌 真由子,中杤 昌弘,金井 仁弘,中山 昌喜,菱田 朝陽,河村 優輔,青柳 有香,久保 充明,鎌谷 洋一郎,横田 充弘,若井 建志,岡田 随象,四ノ宮 成祥,松尾 洋孝,防衛衛生,(一社)日本防衛衛生学会,Vol. 66,No. 別冊,p. 44-44,2018年12月
  • 神経疾患の克服を目指して 横断的オミクス解析による遺伝情報と形質情報の統合,岡田 随象,臨床神経学,(一社)日本神経学会,Vol. 58,No. Suppl.,p. S35-S35,2018年12月
  • 【遺伝子解析研究の新時代】ゲノム解析法の進歩 遺伝統計学とヒトゲノム研究,岡田 随象,医学のあゆみ,医歯薬出版(株),Vol. 266,No. 5,p. 347-354,2018年08月
  • 【最新遺伝医学研究と遺伝カウンセリング(シリーズ3) 最新 多因子遺伝性疾患研究と遺伝カウンセリング】(第1章)総論 ゲノムワイドデータの遺伝統計解析手法,小河 浩太郎,岡田 随象,遺伝子医学MOOK,(株)メディカルドゥ,Vol. 別冊,No. 最新多因子遺伝性疾患研究と遺伝カウンセリング,p. 38-42,2018年06月
  • アレルギー疾患とNon-coding RNA,岡田 随象,アレルギー,(一社)日本アレルギー学会,Vol. 67,No. 4-5,p. 361-361,2018年05月
  • マイクロバイオームは何をもたらすか 横断的オミクス解析による疾患病態解明とゲノム創薬,岡田 随象,アレルギー,(一社)日本アレルギー学会,Vol. 67,No. 4-5,p. 390-390,2018年05月
  • 【遺伝統計学と疾患ゲノムデータ解析 病態解明から個別化医療、ゲノム創薬まで】(第2章)大規模ゲノムデータ解析の最先端 メンデル遺伝病の原因診断における全エクソーム解析,山本 賢一,岡田 随象,遺伝子医学MOOK,(株)メディカルドゥ,No. 33,p. 77-84,2018年04月
  • 【遺伝統計学と疾患ゲノムデータ解析 病態解明から個別化医療、ゲノム創薬まで】(第2章)大規模ゲノムデータ解析の最先端 全ゲノムシークエンス解析,岸川 敏博,岡田 随象,遺伝子医学MOOK,(株)メディカルドゥ,No. 33,p. 85-90,2018年04月
  • 【遺伝統計学と疾患ゲノムデータ解析 病態解明から個別化医療、ゲノム創薬まで】(第4章)開発者によるゲノムデータ解析手法紹介 ゲノム・エピゲノム解析 MIGWAS 疾患ゲノム情報を活用したmiRNAスクリーニング,坂上 沙央里,岡田 随象,遺伝子医学MOOK,(株)メディカルドゥ,No. 33,p. 196-200,2018年04月
  • 【関節リウマチの診断・治療法の進歩:ベストプラクティスを目指して】遺伝統計学からみた関節リウマチ,岡田 随象,Clinical Calcium,(株)医薬ジャーナル社,Vol. 28,No. 5,p. 611-618,2018年04月
  • Precision Medicine in Nephrology 腎臓病学の精密医療 横断的オミクス解析が拓く腎臓病病態解明と精密医療,岡田 随象,日本腎臓学会誌,(一社)日本腎臓学会,Vol. 60,No. 3,p. 282-282,2018年04月
  • オミックス解析からの呼吸器領域へのレッスン ゲノム解析とバイオインフォマティクス,岡田 随象,日本呼吸器学会誌,(一社)日本呼吸器学会,Vol. 7,No. 増刊,p. 13-13,2018年03月
  • 【がん不均一性を理解し、治療抵抗性に挑む がんはなぜ進化するのか?再発するのか?】(第2章)がんの不均一性に伴うがんゲノムの進化 遺伝統計学における選択圧解析とがんゲノム進化解析,岡田 随象,実験医学,(株)羊土社,Vol. 36,No. 2,p. 236-240,2018年02月
  • 【腎泌尿器領域における個別化医療・精密医療】横断的オミクス解析による腎臓病病態解明,岡田 随象,腎臓内科・泌尿器科,(有)科学評論社,Vol. 7,No. 2,p. 154-159,2018年02月
  • 【腎疾患領域のゲノム医療と新規治療ターゲット】ゲノムワイド関連解析による慢性腎臓病リスク遺伝子座の同定とゲノム創薬,金井 仁弘,岡田 随象,腎と骨代謝,(株)日本メディカルセンター,Vol. 31,No. 1,p. 19-26,2018年01月
  • 医療と技術 遺伝統計学による疾患病態解明,岡田 随象,生産と技術 = Manufacturing & technology,生産技術振興協会,Vol. 70,No. 4,p. 77-80,2018年
  • 侵襲性歯周炎の責任遺伝子NOD2の同定,須藤 毅顕,岡田 随象,尾崎 浩一,浦山 ケビン,金井 仁弘,小林 宏明,御給 美沙,田中 敏博,和泉 雄一,日本歯周病学会会誌,(NPO)日本歯周病学会,Vol. 59,No. 秋季特別,p. 183-183,2017年11月
  • 医学統計の基礎-免疫疾患における活用,岡田 随象,免疫学コア講義,p. 276-280,2017年11月,記事・総説・解説・論説等(学術雑誌)
  • 【リウマチ性疾患の遺伝要因】関節リウマチの遺伝要因,岡田 随象,リウマチ科,(有)科学評論社,Vol. 58,No. 4,p. 359-364,2017年10月,記事・総説・解説・論説等(学術雑誌)
  • 遺伝統計学とヒトゲノム解析で迫る急性期疾患,岡田 随象,日本救急医学会雑誌,(一社)日本救急医学会,Vol. 28,No. 9,p. 386-386,2017年09月
  • 【医療ビッグデータの可能性と現状の取り組み】遺伝統計学によるゲノムデータ解析,岡田 随象,生体医工学,(公社)日本生体医工学会,Vol. 55,No. 4,p. 165-172,2017年08月
  • 痛風のゲノムワイド関連解析 新規遺伝子座を含めた10個の痛風関連遺伝子座の同定,中山 昌喜,松尾 洋孝,崎山 真幸,高田 龍平,清水 聖子,東野 俊英,河村 優輔,川口 真,徳増 淳美,大山 恵子,細山田 真,藤森 新,横尾 隆,細谷 龍男,大山 博司,清水 徹,市田 公美,四ノ宮 成祥,中岡 博史,山本 健,久保 充明,鎌谷 洋一郎,中村 好宏,Merriman Tony R.,豊田 優,鈴木 洋史,岡田 随象,若井 建志,痛風と核酸代謝,(一社)日本痛風・尿酸核酸学会,Vol. 41,No. 1,p. 40-41,2017年07月
  • 【骨免疫学の進歩が変える骨関節疾患アプローチ】骨免疫学と新たな治療への展望 骨関節疾患の遺伝子ハンティング,坂上 沙央里,岡田 随象,THE BONE,(株)メディカルレビュー社,Vol. 31,No. 2,p. 205-210,2017年07月,記事・総説・解説・論説等(学術雑誌)
  • 【糖尿病の「体質」:発症する人としない人の違いはなにか?】「体質」の解明の展望とその発展 遺伝因子から創薬へ,水野 彰,岡田 随象,月刊糖尿病,(株)医学出版,Vol. 9,No. 7,p. 72-80,2017年07月
  • 【ゲノムデータベースとこれからの疾患研究】遺伝統計学によるこれからの疾患ゲノム研究,岡田 随象,BIO Clinica,(株)北隆館,Vol. 32,No. 6,p. 565-570,2017年06月,記事・総説・解説・論説等(学術雑誌)
  • ゲノム医療が腎臓病学に果たす役割と展望 遺伝統計解析で迫る腎疾患の病態解明とゲノム創薬,岡田 随象,日本腎臓学会誌,(一社)日本腎臓学会,Vol. 59,No. 3,p. 193-193,2017年04月
  • ヒトゲノムのホモ接合度が認知機能や身長に与える影響,岡田 随象,感染・炎症・免疫,鳥居薬品(株),Vol. 47,No. 1,p. 65-66,2017年04月,記事・総説・解説・論説等(学術雑誌)
  • 【関節リウマチのプレクリニカルステージ】関節リウマチの発症に関連する遺伝的変異,岡田 随象,Keynote R・A,(株)先端医学社,Vol. 5,No. 2,p. 52-56,2017年04月
  • ゲノムワイド関連解析による関節リウマチの病態解明状況は? 解析結果から新薬候補CDK4/6阻害薬を同定,岡田 随象,日本医事新報,(株)日本医事新報社,No. 4846,p. 64-65,2017年03月
  • ゲノムデータから関節リウマチの薬を創る,岡田 随象,VIVA! ORTHO,2017年01月,記事・総説・解説・論説等(学術雑誌)
  • 遺伝統計学による創薬,坂上 沙央里,山本 一彦,岡田 随象,腎臓内科・泌尿器科,(有)科学評論社,Vol. 5,No. 1,p. 82-86,2017年01月
  • ゲノム医療時代の遺伝子関連検査の現状と展望(Vol.3) ゲノム医療時代のバイオインフォマティクス,岸川 敏博,岡田 随象,医学のあゆみ,医歯薬出版(株),Vol. 260,No. 4,p. 332-334,2017年01月
  • アレルギー用語解説シリーズ ゲノム創薬,岡田 随象,アレルギー,(一社)日本アレルギー学会,Vol. 65,No. 9,p. 1231-1231,2016年11月
  • 【関節リウマチ 新規治療薬による寛解への挑戦】トピックス ゲノムワイド関連解析がもたらした関節リウマチの病態の解明と創薬への展開,岡田 随象,Medical Practice,(株)文光堂,Vol. 33,No. 10,p. 1591-1596,2016年10月,記事・総説・解説・論説等(学術雑誌)
  • 【ゲノムデータをどう扱えば、医学と医療は変わるのか 遺伝統計学の力と創薬・個別化医療】「ゲノム情報」+「遺伝統計学」=「ゲノム医療」!?,岡田 随象,実験医学,(株)羊土社,Vol. 34,No. 16,p. 2630-2635,2016年10月,記事・総説・解説・論説等(学術雑誌)
  • これからのゲノム創薬のかたち,平田 潤,吹田直政,実験医学,Vol. 34,No. 16,p. 2675-2676,2016年09月,記事・総説・解説・論説等(学術雑誌)
  • 遺伝統計学が拓く疾患病態解明と創薬,岡田 随象,日本整形外科学会雑誌,(公社)日本整形外科学会,Vol. 90,No. 8,p. S1429-S1429,2016年08月
  • 【関節リウマチ早期診断・治療のための必須知識】RAの疾患感受性遺伝子の同定と創薬研究への応用,吹田 直政,岡田 随象,Orthopaedics,(株)全日本病院出版会,Vol. 29,No. 7,p. 1-9,2016年07月,記事・総説・解説・論説等(学術雑誌)
  • 自己免疫疾患における大規模ヒトゲノム解析の現状,岡田 随象,アレルギー,(一社)日本アレルギー学会,Vol. 65,No. 7,p. 921-5,2016年07月
  • HLA imputation法 日本人集団における実装,金井 仁弘,岡田 随象,医学のあゆみ,医歯薬出版(株),Vol. 257,No. 9,p. 939-940,2016年05月,記事・総説・解説・論説等(学術雑誌)
  • ROHgenコンソーシアムが解いたMissing Heritability,岡田 随象,実験医学,(株)羊土社,Vol. 34,No. 6,p. 966-970,2016年04月,記事・総説・解説・論説等(学術雑誌)
  • ゲノム情報に基づく関節リウマチの病態解析と創薬,平田 潤,田中 敏博,岡田 随象,リウマチ科,(有)科学評論社,Vol. 55,No. 3,p. 309-314,2016年03月,記事・総説・解説・論説等(学術雑誌)
  • 病原微生物と免疫異常 大規模ヒト疾患ゲノム解析による疾患病態解明・新規創薬への展望,岡田 随象,日本臨床免疫学会会誌,日本臨床免疫学会,Vol. 38,No. 4,p. 249-249,2015年09月
  • 遺伝統計学におけるゲノムワイド関連解析の現状,岡田 随象,日本臨床免疫学会会誌,日本臨床免疫学会,Vol. 38,No. 4,p. 283-283,2015年09月
  • 【リウマチ性疾患のゲノム&エピゲノム解析-GWASから次世代シークエンサーの時代へ-】GWASの情報をどう活用するか?,岡田 随象,分子リウマチ治療,(株)先端医学社,Vol. 8,No. 3,p. 115-120,2015年07月
  • 大規模ヒトゲノム解析で迫る関節リウマチの疾患病態と新規創薬,岡田 随象,感染・炎症・免疫,鳥居薬品(株),Vol. 45,No. 1,p. 20-30,2015年04月
  • アレルギーと遺伝子多型 自己免疫疾患における大規模ヒトゲノム解析の現状,岡田 随象,アレルギー,(一社)日本アレルギー学会,Vol. 64,No. 3-4,p. 298-298,2015年04月
  • 関節リウマチ遺伝子同定による診断法と治療法,岡田 随象,内分泌・糖尿病・代謝内科,(有)科学評論社,Vol. 40,No. 4,p. 312-320,2015年04月
  • 【遺伝因子同定から発症機序解明と治療法開発に向けて】肥満遺伝子領域の同定と発症機序解明に向けて,岡田 随象,田中 敏博,内分泌・糖尿病・代謝内科,(有)科学評論社,Vol. 40,No. 4,p. 260-267,2015年04月
  • HLA imputation法の日本人集団への実装とバセドウ病バイオマーカーの同定,岡田 随象,実験医学,Vol. 33,No. 16,p. 2617-2621,2015年,記事・総説・解説・論説等(学術雑誌)
  • HLA遺伝子の網羅的解析による自己免疫疾患の発症および病態進展に関わるバイオマーカーの同定 (平成26年度研究奨励金受領報告) -- (自己免疫疾患治療の新展開),岡田 随象,東京生化学研究会助成研究報告集,東京生化学研究会,Vol. 30,p. 154-156,2015年
  • 【ヒト免疫学の新機軸】ゲノム解析 Common diseaseである自己免疫疾患のゲノム解析,岡田 随象,医学のあゆみ,医歯薬出版(株),Vol. 252,No. 1,p. 17-24,2015年01月
  • ゲノム科学からゲノム医療へ ゲノム解析の時代からゲノム創薬の時代へ,岡田 随象,血管医学,(株)メディカルレビュー社,Vol. 15,No. 4,p. 415-421,2014年12月
  • 【関節リウマチの早期診断と治療】関節リウマチの疾患感受性遺伝子,岡田 随象,Keynote R・A,(株)先端医学社,Vol. 2,No. 4,p. 180-184,2014年10月
  • 【血小板研究の最近の進歩】血小板数と血小板体積を決定する遺伝因子 大規模ヒトゲノム解析の成果,岡田 随象,医学のあゆみ,医歯薬出版(株),Vol. 251,No. 2,p. 173-178,2014年10月
  • ゲノムと環境 自己免疫疾患におけるゲノムワイド関連解析,岡田 随象,日本臨床免疫学会会誌,日本臨床免疫学会,Vol. 37,No. 4,p. 266-266,2014年08月
  • 【骨免疫学の最新の話題】遺伝子解析からみた骨免疫学,岡田 随象,炎症と免疫,(株)先端医学社,Vol. 22,No. 5,p. 350-354,2014年08月
  • 痛風と高尿酸血症に関連する遺伝子の最新知識,岡田 随象,鎌谷 直之,痛風と核酸代謝,(一社)日本痛風・尿酸核酸学会,Vol. 38,No. 1,p. 1-12,2014年07月
  • ビッグデータ解析による新しいゲノム創薬手法の開発 関節リウマチを例に,岡田 随象,実験医学,Vol. 32,No. 11,p. 1759-1762,2014年,記事・総説・解説・論説等(学術雑誌)
  • 自己免疫疾患の遺伝子解析 ゲノム情報から機能解析へ,山本 一彦,高地 雄太,鈴木 亜香里,岡田 随象,山田 亮,最新医学,(株)最新医学社,Vol. 68,No. 3,p. 430-451,2013年03月
  • 企業内診療所における禁煙外来の有用性について,吉野 友祐,田中 理恵子,岡田 随象,北沢 貴利,太田 康男,根本 博,日本禁煙学会雑誌,(一社)日本禁煙学会,Vol. 7,No. 2,p. 54-56,2012年04月
  • INTERFACE 臨床 血小板、凝固、線溶のゲノムワイド関連解析,岡田 随象,International Review of Thrombosis,(株)メディカルレビュー社,Vol. 6,No. 4,p. 330-335,2011年12月
  • 遺伝・ゲノム学 ゲノムワイド関連解析による日本人集団における血液学的・生化学的形質関連遺伝子の同定,鎌谷 洋一郎,岡田 随象,医学のあゆみ,医歯薬出版(株),Vol. 234,No. 12,p. 1125-1127,2010年09月
  • 血球貪食症候群様の病態を来し、リンパ節生検で当初Angioimmunoblastic T-cell Lymphomaと病理診断されたMethotrexate関連リンパ増殖性疾患の一例,萩野 昇,奥西 勝秀,朝田 一生,岡田 随象,松本 拓,篠原 聡,田中 良一,沢田 哲治,土肥 真,三崎 義堅,山本 一彦,関東リウマチ,関東リウマチ研究会,No. 41,p. 233-242,2008年02月
  • 海外事情 キューバ・モデルの現状と展望--Vedado Educational Polyclinicでの医学実習を通じて,岡田 随象,公衆衛生,Vol. 69,No. 4,p. 305-307,2005年,記事・総説・解説・論説等(学術雑誌)

著書

  • ゼロから実践する遺伝統計学セミナー : 疾患とゲノムを結びつける,岡田, 随象,羊土社,ISBN:9784758120920,2020年
  • 遺伝統計学と疾患ゲノムデータ解析 : 病態解明から個別化医療, ゲノム創薬まで,岡田, 随象,メディカルドゥ,ISBN:9784944157631,2018年
  • 「特集」ゲノムデータをどう扱えば、医学と医療は変わるのか : 遺伝統計学の力と創薬・個別化医療,岡田, 随象,羊土社,ISBN:9784758101561,2016年10月

特許・実用新案・意匠

  • 関節リウマチを検査する方法,岡田 随象,特願2018171296,出願日:2018年09月13日
  • 第6染色体短腕22領域または第9染色体長腕21領域の一塩基多型に基づく肥満の検査方法,岡田 随象,特許JP5954724B2,特願2011162177,出願日:2011年07月25日

受賞

  • 大阪大学栄誉教授(称号付与),大阪大学,2020年
  • 理事長賞,日本医療研究開発機構(AMED),2020年
  • 日本学術振興会賞,日本学術振興会,2020年
  • 井上リサーチアウォード,岡田 随象,2017年02月
  • 医学研究奨励賞,岡田 随象,日本医師会,2016年10月
  • ゴールド・メダル賞,岡田 随象,読売テクノフォーラム,2016年04月
  • 若手科学者賞,岡田 随象,文部科学大臣表彰,2015年05月
  • 三浦記念リウマチ学術研究賞,岡田 随象,財団法人日本リウマチ財団,2015年04月
  • 田辺三菱賞,岡田 随象,公益財団法人痛風財団,2014年12月
  • 奨励賞,岡田 随象,日本リウマチ学会,2014年04月
  • ASHG/Charles J. Epstein Trainee Award for Excellence in Human Genetics Research - Finalist,岡田 随象,2013年10月
  • 第49回 ベルツ賞(2等),岡田 随象,2012年11月
  • 奨励賞,岡田 随象,日本人類遺伝学会,2012年10月
  • 総長賞,岡田 随象,東京大学,2012年03月