EN

基本情報

研究

社会活動

その他の活動

李 鍾國

Ri Shoukoku

医学系研究科,特任教授(常勤)

keyword イオンチャネル,心臓不整脈,バイオペースメーカ

学歴

  • 1993年 ~ 1998年,名古屋大学,大学院医学系研究科,循環器学
  • 1981年 ~ 1987年,名古屋大学,医学部医学科

経歴

  • 2019年 ~ 継続中,大阪大学大学院医学系研究科,心血管再生医学共同研究講座,特任教授(常勤)
  • 2016年 ~ 2019年,大阪大学大学院医学系研究科,先進心血管再生医学共同研究講座,特任准教授(常勤)
  • 2010年 ~ 2016年,大阪大学大学院医学系研究科,心血管再生医学寄附講座,寄附講座准教授
  • 2007年 ~ 2010年,名古屋大学,環境医学研究所,准教授
  • 2004年 ~ 2007年,名古屋大学 環境医学研究所 助教授
  • 1998年 ~ 2004年,名古屋大学 環境医学研究所 助手
  • 1995年 ~ 1998年,カリフォルニア大学ロサンゼルス校医学部,循環器内科学,博士研究員

研究内容・専門分野

  • ライフサイエンス,医療薬学
  • ライフサイエンス,生理学
  • ライフサイエンス,循環器内科学
  • ライフサイエンス,生体材料学
  • ライフサイエンス,生体医工学

所属学会

  • 日本心血管インターベンション学会
  • 日本臨床薬理学会
  • 日本薬理学会
  • 日本内科学会
  • 日本心電学会
  • 日本循環器学会
  • Japanese Society of Interventional Cardiology
  • The Japanese Society of Clinical Pharmacology and Therapeutics
  • The Japanese Pharmacological Society

論文

  • Scaffold-Mediated Developmental Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Are Preserved After External Support Removal.,Jun Li,Jong-Kook Lee,Keiko Miwa,Yuki Kuramoto,Kiyoshi Masuyama,Hideki Yasutake,Satoki Tomoyama,Hiroyuki Nakanishi,Yasushi Sakata,Frontiers in cell and developmental biology,Vol. 9,p. 591754-591754,2021年,研究論文(学術雑誌)
  • Activation of DNA Damage Response and Cellular Senescence in Cardiac Fibroblasts Limit Cardiac Fibrosis After Myocardial Infarction.,Shibamoto M,Higo T,Naito AT,Nakagawa A,Sumida T,Okada K,Sakai T,Kuramoto Y,Yamaguchi T,Ito M,Masumura Y,Higo S,Lee JK,Hikoso S,Komuro I,Sakata Y,International heart journal,Vol. 60,No. 4,p. 944-957,2019年07月
  • Geometrical Patterning and Constituent Cell Heterogeneity Facilitate Electrical Conduction Disturbances in a Human Induced Pluripotent Stem Cell-based Platform: an in vitro Disease Model of Atrial Arrhythmias,Nakanishi H,Lee JK,Miwa K,Masuyama K,Yasutake H,Li J,Tomoyama S,Honda Y,Deguchi J,Tsujimoto S,Hidaka K,Miyagawa S,Sawa Y,Komuro I,Sakata Y,Frontiers in Physiology,Vol. 10,2019年06月,研究論文(学術雑誌)
  • ヒトiPS細胞由来心房筋様細胞単層シートにおける電気伝導性は、幾何学形状及び構成細胞の不均一性によって不安定化する ~肺静脈-左心房境界部を模倣した<i>in vitro</i>での構造的及び電気生理学的モデルでの検証,李 鍾國,中西 浩之,小室 一成,坂田 泰史,日本薬理学会年会要旨集,公益社団法人 日本薬理学会,Vol. 92,No. 0,p. 1-P-075,2019年
  • Author Correction: Activation of endothelial β-catenin signaling induces heart failure.,Akito Nakagawa,Atsuhiko T Naito,Tomokazu Sumida,Seitaro Nomura,Masato Shibamoto,Tomoaki Higo,Katsuki Okada,Taku Sakai,Akihito Hashimoto,Yuki Kuramoto,Toru Oka,Jong-Kook Lee,Mutsuo Harada,Kazutaka Ueda,Ichiro Shiojima,Florian P Limbourg,Ralf H Adams,Tetsuo Noda,Yasushi Sakata,Hiroshi Akazawa,Issei Komuro,Scientific reports,Vol. 8,No. 1,p. 15858-15858,2018年10月29日
  • In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects.,Yoshida A,Lee JK,Tomoyama S,Miwa K,Shirakawa K,Hamanaka S,Yamaguchi T,Nakauchi H,Miyagawa S,Sawa Y,Komuro I,Sakata Y,Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,Vol. 20,No. 9,p. 1553-1560,2018年09月
  • Phenotypic Screening Using Patient-Derived Induced Pluripotent Stem Cells Identified Pyr3 as a Candidate Compound for the Treatment of Infantile Hypertrophic Cardiomyopathy,Taku Sakai,Atsuhiko T. Naito,Yuki Kuramoto,Masamichi Ito,Katsuki Okada,Tomoaki Higo,Akito Nakagawa,Masato Shibamoto,Toshihiro Yamaguchi,Tomokazu Sumida,Seitaro Nomura,Akihiro Umezawa,Shigeru Miyagawa,Yoshiki Sawa,Hiroyuki Morita,Jong-Kook Lee,Ichiro Shiojima,Yasushi Sakata,Issei Komuro,INTERNATIONAL HEART JOURNAL,INT HEART JOURNAL ASSOC,Vol. 59,No. 5,p. 1096-1105,2018年09月,研究論文(学術雑誌)
  • Generation of Fabry cardiomyopathy model for drug screening using induced pluripotent stem cell-derived cardiomyocytes from a female Fabry patient.,Yuki Kuramoto,Atsuhiko T Naito,Hiromasa Tojo,Taku Sakai,Masamichi Ito,Masato Shibamoto,Akito Nakagawa,Tomoaki Higo,Katsuki Okada,Toshihiro Yamaguchi,Jong-Kook Lee,Shigeru Miyagawa,Yoshiki Sawa,Yasushi Sakata,Issei Komuro,Journal of molecular and cellular cardiology,Vol. 121,p. 256-265,2018年08月,研究論文(学術雑誌)
  • In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects.,Yoshida A,Lee JK,Tomoyama S,Miwa K,Shirakawa K,Hamanaka S,Yamaguchi T,Nakauchi H,Miyagawa S,Sawa Y,Komuro I,Sakata Y,Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,Vol. 20,No. 9,p. 1553-1560,2018年03月
  • Quantification of sympathetic hyperinnervation and denervation after myocardial infarction by three-dimensional assessment of the cardiac sympathetic network in cleared transparent murine hearts,Teruki Yokoyama,Jong-Kook Lee,Keiko Miwa,Tobias Opthof,Satoki Tomoyama,Hiroyuki Nakanishi,Akira Yoshida,Haruyo Yasui,Tadatsune Iida,Shigeru Miyagawa,Shigeo Okabe,Yoshiki Sawa,Yasushi Sakata,Issei Komuro,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 12,No. 7,2017年07月,研究論文(学術雑誌)
  • Quantification of sympathetic hyperinnervation and denervation after myocardial infarction by three-dimensional assessment of the cardiac sympathetic network in cleared transparent murine hearts,Teruki Yokoyama,Jong-Kook Lee,Keiko Miwa,Tobias Opthof,Satoki Tomoyama,Hiroyuki Nakanishi,Akira Yoshida,Haruyo Yasui,Tadatsune Iida,Shigeru Miyagawa,Shigeo Okabe,Yoshiki Sawa,Yasushi Sakata,Issei Komuro,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 12,No. 7,2017年07月,研究論文(学術雑誌)
  • Pivotal role of non-cardiomyocytes in electromechanical and therapeutic potential of induced pluripotent stem cell-derived engineered cardiac tissue.,Iseoka H,Tissue Eng Prt A,2017年05月,研究論文(学術雑誌)
  • DNA single-strand break-induced DNA damage response causes heart failure,Tomoaki Higo,Atsuhiko T. Naito,Tomokazu Sumida,Masato Shibamoto,Katsuki Okada,Seitaro Nomura,Akito Nakagawa,Toshihiro Yamaguchi,Taku Sakai,Akihito Hashimoto,Yuki Kuramoto,Masamichi Ito,Shungo Hikoso,Hiroshi Akazawa,Jong-Kook Lee,Ichiro Shiojima,Peter J. McKinnon,Yasushi Sakata,Issei Komuro,NATURE COMMUNICATIONS,NATURE PUBLISHING GROUP,Vol. 8,2017年04月,研究論文(学術雑誌)
  • An EP4 receptor agonist inhibits cardiac fibrosis through activation of PKA signaling in hypertrophied heart,Qi Wang,Toru Oka,Kiyoshi Yamagami,Jong-Kook Lee,Hiroshi Akazawa,Atsuhiko T. Naito,Taku Yasui,Takamaru Ishizu,Yoshikazu Nakaoka,Yasushi Sakata,Issei Komuro,International Heart Journal,International Heart Journal Association,Vol. 58,No. 1,p. 107-114,2017年,研究論文(学術雑誌)
  • Tissue Clearance Technique Enables to Investigate Three-Dimensional Distribution of Cardiac Sympathetic Nervous System,Teruki Yokoyama,Jong-Kook Lee,Keiko Miwa,Satoki Tomoyama,Hiroyuki Nakanishi,Akira Yoshida,Shigeru Miyagawa,Yoshiki Sawa,Yasushi Sakata,Issei Komuro,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月
  • A New In Vitro Co-Culture Model Using Magnetic Force-Based Nanotechnology.,Takanari H,Miwa K,Fu X,Nakai J,Ito A,Ino K,Honda H,Tonomura W,Konishi S,Opthof T,van der Heyden MA,Kodama I,Lee JK,Journal of cellular physiology,Vol. 231,No. 10,p. 2249-2256,2016年10月,研究論文(学術雑誌)
  • Activation of endothelial β-catenin signaling induces heart failure.,Nakagawa A,Naito AT,Sumida T,Nomura S,Shibamoto M,Higo T,Okada K,Sakai T,Hashimoto A,Kuramoto Y,Oka T,Lee JK,Harada M,Ueda K,Shiojima I,Limbourg FP,Adams RH,Noda T,Sakata Y,Akazawa H,Komuro I,Scientific reports,Vol. 6,2016年05月
  • Generation of Induced Pluripotent Stem Cells From Patients With Duchenne Muscular Dystrophy and Their Induction to Cardiomyocytes.,Hashimoto A,Naito AT,Lee JK,Kitazume-Taneike R,Ito M,Yamaguchi T,Nakata R,Sumida T,Okada K,Nakagawa A,Higo T,Kuramoto Y,Sakai T,Tominaga K,Okinaga T,Kogaki S,Ozono K,Miyagawa S,Sawa Y,Sakata Y,Morita H,Umezawa A,Komuro I,International heart journal,Vol. 57,No. 1,p. 112-117,2016年
  • DNA Single-strand Break-induced DNA Damage Response Causes Heart Failure,Higo Tomoaki,Naito Atsuhiko,Shibamoto Masato,Lee Jong-Kook,Hikoso Shungo,Sakata Yasushi,Komuro Issei,CIRCULATION,Vol. 132,2015年11月10日
  • Monocyte-derived extracellular Nampt-dependent biosynthesis of NAD(+) protects the heart against pressure overload.,Yano M,Akazawa H,Oka T,Yabumoto C,Kudo-Sakamoto Y,Kamo T,Shimizu Y,Yagi H,Naito AT,Lee JK,Suzuki J,Sakata Y,Komuro I,Scientific reports,Vol. 5,2015年11月
  • Angiotensin II receptor blockade promotes repair of skeletal muscle through down-regulation of aging-promoting C1q expression.,Yabumoto C,Akazawa H,Yamamoto R,Yano M,Kudo-Sakamoto Y,Sumida T,Kamo T,Yagi H,Shimizu Y,Saga-Kamo A,Naito AT,Oka T,Lee JK,Suzuki J,Sakata Y,Uejima E,Komuro I,Scientific reports,Vol. 5,2015年09月
  • Pirfenidone exhibits cardioprotective effects by regulating myocardial fibrosis and vascular permeability in pressure-overloaded hearts.,Yamagami K,Oka T,Wang Q,Ishizu T,Lee JK,Miwa K,Akazawa H,Naito AT,Sakata Y,Komuro I,American journal of physiology. Heart and circulatory physiology,Vol. 309,No. 3,p. H512-22,2015年08月
  • Wnt/beta-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box O,Katsuki Okada,Atsuhiko T. Naito,Tomoaki Higo,Akito Nakagawa,Masato Shibamoto,Taku Sakai,Akihito Hashimoto,Yuki Kuramoto,Tomokazu Sumida,Seitaro Nomura,Masamichi Ito,Toshihiro Yamaguchi,Toru Oka,Hiroshi Akazawa,Jong-Kook Lee,Sachio Morimoto,Yasushi Sakata,Ichiro Shiojima,Issei Komuro,CIRCULATION-HEART FAILURE,LIPPINCOTT WILLIAMS & WILKINS,Vol. 8,No. 4,p. 799-U211,2015年07月,研究論文(学術雑誌)
  • Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling.,Sumida T,Naito AT,Nomura S,Nakagawa A,Higo T,Hashimoto A,Okada K,Sakai T,Ito M,Yamaguchi T,Oka T,Akazawa H,Lee JK,Minamino T,Offermanns S,Noda T,Botto M,Kobayashi Y,Morita H,Manabe I,Nagai T,Shiojima I,Komuro I,Nature communications,Vol. 6,2015年02月
  • Regeneration of the Cardiac Conduction System by Adipose Tissue-Derived Stem Cells.,Takahashi T,Nagai T,Kanda M,Liu ML,Kondo N,Naito AT,Ogura T,Nakaya H,Lee JK,Komuro I,Kobayashi Y,Circulation journal : official journal of the Japanese Circulation Society,Vol. 79,No. 12,p. 2703-2712,2015年
  • Excitation propagation in three-dimensional engineered hearts using decellularized extracellular matrix.,Yasui H,Lee JK,Yoshida A,Yokoyama T,Nakanishi H,Miwa K,Naito AT,Oka T,Akazawa H,Nakai J,Miyagawa S,Sawa Y,Sakata Y,Komuro I,Biomaterials,Vol. 35,No. 27,p. 7839-7850,2014年09月,研究論文(学術雑誌)
  • Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling.,Kudo-Sakamoto Y,Akazawa H,Ito K,Takano J,Yano M,Yabumoto C,Naito AT,Oka T,Lee JK,Sakata Y,Suzuki J,Saido TC,Komuro I,The Journal of biological chemistry,Vol. 289,No. 28,p. 19408-19419,2014年07月,研究論文(学術雑誌)
  • Rapid electrical stimulation causes alterations in cardiac intercellular junction proteins of cardiomyocytes,Tadamitsu Nakashima,Tomoko Ohkusa,Yoko Okamoto,Masaaki Yoshida,Jong-Kook Lee,Yoichi Mizukami,Masafumi Yano,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 306,No. 9,p. H1324-H1333,2014年05月,研究論文(学術雑誌)
  • Electrical Propagation of Three-Dimensional Engineered Hearts using Decellularized Extracellular Matrix,Haruyo Yasui,Jong-Kook Lee,Akira Yoshida,Teruki Yokoyama,Junichi Nakai,Issei Komuro,BIOPHYSICAL JOURNAL,CELL PRESS,Vol. 106,No. 2,p. 630A-630A,2014年01月
  • N-glycans: phenotypic homology and structural differences between myocardial cells and induced pluripotent stem cell-derived cardiomyocytes.,Kawamura T,Miyagawa S,Fukushima S,Yoshida A,Kashiyama N,Kawamura A,Ito E,Saito A,Maeda A,Eguchi H,Toda K,Lee JK,Miyagawa S,Sawa Y,PloS one,Vol. 9,No. 10,2014年,研究論文(学術雑誌)
  • Cardiac beta -catenin Alterations Play an Important Role in Gap Junction Remodeling of Cardiomyocytes Exposed to Rapid Electrical Stimulation,Nakashima Tadamitsu,Ohkusa Tomoko,Yoshida Masaaki,Lee Jong-Kook,Mizukami Yoichi,Yano Masafumi,JOURNAL OF CARDIAC FAILURE,Vol. 19,No. 10,2013年10月
  • Notch activation mediates angiotensin II-induced vascular remodeling by promoting the proliferation and migration of vascular smooth muscle cells.,Ozasa Y,Akazawa H,Qin Y,Tateno K,Ito K,Kudo-Sakamoto Y,Yano M,Yabumoto C,Naito AT,Oka T,Lee JK,Minamino T,Nagai T,Kobayashi Y,Komuro I,Hypertension research : official journal of the Japanese Society of Hypertension,Vol. 36,No. 10,p. 859-865,2013年10月,研究論文(学術雑誌)
  • Sympathetic innervation induced in engrafted engineered cardiomyocyte sheets by glial cell line derived neurotrophic factor in vivo.,Fu XM,Lee JK,Miwa K,Shimizu T,Takagishi Y,Hirabayashi M,Watabe K,Usui A,Kodama I,Ueda Y,BioMed Research International,Vol. 2013,2013年08月,研究論文(学術雑誌)
  • Axon guidance of sympathetic neurons to cardiomyocytes by glial cell line-derived neurotrophic factor (GDNF).,Miwa K,Lee JK,Takagishi Y,Opthof T,Fu X,Hirabayashi M,Watabe K,Jimbo Y,Kodama I,Komuro I,PloS One,Vol. 8,No. 7,2013年07月,研究論文(学術雑誌)
  • Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes (vol 149, pg 1298, 2012),Atsuhiko T. Naito,Tomokazu Sumida,Seitaro Nomura,Mei-Lan Liu,Tomoaki Higo,Akito Nakagawa,Katsuki Okada,Taku Sakai,Akihito Hashimoto,Yurina Hara,Ippei Shimizu,Weidong Zhu,Haruhiro Toko,Akemi Katada,Hiroshi Akazawa,Toru Oka,Jong-Kook Lee,Tohru Minamino,Toshio Nagai,Kenneth Walsh,Akira Kikuchi,Misako Matsumoto,Marina Botto,Ichiro Shiojima,Issei Komuro,CELL,CELL PRESS,Vol. 150,No. 3,p. 659-660,2012年08月
  • Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes,Atsuhiko T. Naito,Tomokazu Sumida,Seitaro Nomura,Mei-Lan Liu,Tomoaki Higo,Akito Nakagawa,Katsuki Okada,Taku Sakai,Akihito Hashimoto,Yurina Hara,Ippei Shimizu,Weidong Zhu,Haruhiro Toko,Akemi Katada,Hiroshi Akazawa,Toru Oka,Jong-Kook Lee,Tohru Minamino,Toshio Nagai,Kenneth Walsh,Akira Kikuchi,Misako Matsumoto,Marina Botto,Ichiro Shiojima,Issei Komuro,CELL,CELL PRESS,Vol. 149,No. 6,p. 1298-1313,2012年06月,研究論文(学術雑誌)
  • Rate-dependent shortening of action potential duration increases ventricular vulnerability in failing rabbit heart.,Harada M,Tsuji Y,Ishiguro YS,Takanari H,Okuno Y,Inden Y,Honjo H,Lee JK,Murohara T,Sakuma I,Kamiya K,Kodama I,American journal of physiology. Heart and circulatory physiology,Vol. 300,No. 2,p. H565-73,2011年02月,研究論文(学術雑誌)
  • Glial cell line-derived neurotrophic factor (GDNF) enhances sympathetic neurite growth in rat hearts at early developmental stages,Keiko Miwa,Jong-Kook Lee,Yoshiko Takagishi,Tobias Opthof,Xianming Fu,Itsuo Kodama,BIOMEDICAL RESEARCH-TOKYO,BIOMEDICAL RESEARCH PRESS LTD,Vol. 31,No. 6,p. 353-361,2010年12月,研究論文(学術雑誌)
  • 心臓に対する骨格筋芽細胞パターニング移植は細胞のランダム注入に比べて催不整脈作用を軽減する 培養細胞を用いた検討,高成 広起,李 鍾国,三輪 佳子,児玉 逸雄,心電図,(一社)日本不整脈心電学会,Vol. 28,No. 5,p. 466-466,2008年10月
  • 骨格筋芽細胞移植による心臓再生治療 in-vitroモデルを用いた催不整脈性の検討,高成 広起,李 鍾国,三輪 佳子,伊野 浩介,本多 裕之,児玉 逸雄,Circulation Journal,(一社)日本循環器学会,Vol. 72,No. Suppl.III,p. 1087-1087,2008年10月
  • Changes of HCN gene expression and I(f) currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation.,Yano S,Miake J,Mizuta E,Manabe K,Bahrudin U,Morikawa K,Arakawa K,Sasaki N,Igawa O,Shigemasa C,Yamamoto Y,Morisaki T,Hidaka K,Kurata Y,Yoshida A,Shiota G,Higaki K,Ninomiya H,Lee JK,Shirayoshi Y,Hisatome I,Biomedical research (Tokyo, Japan),Vol. 29,No. 4,p. 195-203,2008年08月,研究論文(学術雑誌)
  • 心房拡大に伴う心房細動発生基質の成立とベプリジルの抗細動効果について,植田 典浩,山本 充,本荘 晴朗,高成 広起,石黒 有子,原田 将英,李 鍾国,神谷 香一郎,児玉 逸雄,Circulation Journal,(一社)日本循環器学会,Vol. 71,No. Suppl.II,p. 842-842,2007年04月
  • Combined effects of nifekalant and lidocaine on the spiral-type re-entry in a perfused 2-dimensional layer of rabbit ventricular myocardium.,Amino M,Yamazaki M,Nakagawa H,Honjo H,Okuno Y,Yoshioka K,Tanabe T,Yasui K,Lee JK,Horiba M,Kamiya K,Kodama I,Circulation journal : official journal of the Japanese Circulation Society,Vol. 69,No. 5,2005年05月,研究論文(学術雑誌)

MISC

  • In Vitro Model of Allogenic Cell Transplantation for Conduction Defects - Electrical Coupling Between Rat iPS Cell-Derived Cardiac Cells and Rat Native Cardiac Cells,Akira Yoshida,Jong-Kook Lee,Shigeru Miyagawa,Yoshiki Sawa,Yasushi Sakata,Issei Komuro,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月,研究発表ペーパー・要旨(国際会議)
  • LIF徐放性ハイドロゲルを用いた心筋・神経共培養系における神経伸長効果の検討,三輪 佳子,横山 光樹,宮川 繁,田畑 泰彦,澤 芳樹,李 鍾國,日本バイオマテリアル学会大会予稿集,日本バイオマテリアル学会,Vol. 37回,p. 334-334,2015年11月
  • Wnt/β-catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction with FoxO,Okada Katsuki,Naitoh Atsuhiko,Lee Jong-Kook,Sakata Yasushi,Shiojima Ichiro,Komuro Issei,Circulation Journal,Vol. 79,No. Suppl.I,p. 680-680,2015年03月
  • Development of Functional Tissue engineered Artificial Cardiac Construct using Human Induced Pluripotent Stem Cells; Optimizing the Cell Components to Mimic Cardiac Tissue,Hiroko Iseoka,Shigeru Miyagawa,Satsuki Fukushima,Shigeo Masuda,Noriko Mochizuki-Oda,Atsuhiro Saito,Emiko Ito,Tsuyoshi Ishikawa,Jong-Kook Lee,Yoshiki Sawa,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 130,2014年11月,研究発表ペーパー・要旨(国際会議)
  • Gap Junction Remodeling and Arrhythmogenesis during Development of Heart Disease,Tomoko Ohkusa,Haruo Honjo,Jong-Kook Lee,Itsuo Kodama,JOURNAL OF PHYSIOLOGICAL SCIENCES,SPRINGER JAPAN KK,Vol. 63,p. S77-S77,2013年,研究発表ペーパー・要旨(国際会議)
  • ラット心臓におけるマウスES細胞由来ペースメーカー細胞により生じる異所性ペーシング(Ectopic pacing generated by the pacemaker cells derived from mouse ES cells in rat heart),池内 悠,清水 夏海,伊藤 真一,藤井 裕史,森川 久未,白吉 安昭,久留 一郎,李 鍾國,日本生化学会大会・日本分子生物学会年会合同大会講演要旨集,(公社)日本生化学会,Vol. 83回・33回,p. 4P-0904,2010年12月
  • Induction of Sympathetic Innervation to Stem Cell-Derived Cardiomyocytes,Jong-Kook Lee,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 16,No. 9,p. S139-S139,2010年09月,研究発表ペーパー・要旨(国際会議)
  • The cellular prion protein identifies bipotential cardiomyogenic progenitors,Kyoko Hidaka,Manabu Shirai,Jong-Kook Lee,Takanari Wakayama,Itsuo Kodama,Michael D. Schneider,Takayuki Morisaki,Circulation Research,Vol. 106,No. 1,p. 111-119,2010年
  • Axon Guidance of Sympathetic Neurons to Native and Induced Pluripotent Stem (iPS) Cell-Derived Cardiomyocytes Using Glial Cell Line-Derived Neurotrophic Factor (GDNF),Keiko Miwa,Jong-Kook Lee,Yoshiko Takagishi,Yasuhiko Jimbo,Tobias Opthof,Itsuo Kodama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 120,No. 18,p. S809-S809,2009年11月,研究発表ペーパー・要旨(国際会議)
  • Brown Adipose Tissue Derived-cells Differentiate Into Cardiac Conduction and Pace-maker Cells in vitro and Improve Complete AV Block in vivo,Toshinao Takahashi,Toshio Nagai,Atsuhiko T. Naito,Masato Kanda,Masakuni Tokunaga,Meiran Liu,Takehiko Ogura,Jong-Kook Lee,Itsuo Kodama,Haruaki Nakaya,Issei Komuro,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 120,No. 18,p. S721-S721,2009年11月,研究発表ペーパー・要旨(国際会議)
  • Regeneration of Cardiac Conduction System by Adipose Tissue Derived-stem Cells,Toshio Nagai,Toshinao Takahashi,Atsuhiko T. Naito,Takehiko Ogura,Haruaki Nakaya,Huijie Dong,Itsuo Kodama,Jong-Kook Lee,Issei Komuro,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 15,No. 7,p. S149-S149,2009年09月,研究発表ペーパー・要旨(国際会議)
  • Brown Adipose Tissue-Derived Cells Differentiate into Cardiac Conduction and Pacemaker Cells in Vitro and Improve Complete AV Block in Vivo,Toshinao Takahashi,Toshio Nagai,Masato Kanda,Masakuni Tokunaga,Meiran Liu,Atsuhiko T. Naito,Takehiko Ogura,Jong-Kook Lee,Itsuo Kodama,Issei Komuro,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 105,No. 7,p. E40-E40,2009年09月,研究発表ペーパー・要旨(国際会議)
  • Effects of Aldosterone on Cx43 Gap Junction Expression in Neonatal Rat Cultured Cardiomyocytes,Shinsuke Suzuki,Tomoko Ohkusa,Takashi Sato,Masaaki Yoshida,Kenji Yasui,Keiko Miwa,Jong-Kook Lee,Masafumi Yano,Itsuo Kodama,Masunori Matsuzaki,CIRCULATION JOURNAL,JAPANESE CIRCULATION SOC,Vol. 73,No. 8,p. 1504-1512,2009年08月
  • Effects of Aldosterone on Cx43 Gap Junction Expression in Neonatal Rat Cultured Cardiomyocytes,Shinsuke Suzuki,Tomoko Ohkusa,Takashi Sato,Masaaki Yoshida,Kenji Yasui,Keiko Miwa,Jong-Kook Lee,Masafumi Yano,Itsuo Kodama,Masunori Matsuzaki,CIRCULATION JOURNAL,JAPANESE CIRCULATION SOC,Vol. 73,No. 8,p. 1504-1512,2009年08月
  • The Cellular Prion Protein Identifies Bipotential Cardiomyogenic Progenitors.,Circulation Research,2009年
  • Paracrine factors of vascular endothelial cells facilitate cardiomyocyte differentiation of mouse embryonic stem cells,Miwako Kado,Jong-Kook Lee,Yoko Hidaka,Keiko Miwa,Toyoaki Murohara,Kenji Kasai,Shinsuke Saga,Takayuki Morisaki,Yuichi Ueda,Itsuo Kodama,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 377,No. 2,p. 413-418,2008年12月
  • Paracrine factors of vascular endothelial cells facilitate cardiomyocyte differentiation of mouse embryonic stem cells,Miwako Kado,Jong-Kook Lee,Yoko Hidaka,Keiko Miwa,Toyoaki Murohara,Kenji Kasai,Shinsuke Saga,Takayuki Morisaki,Yuichi Ueda,Itsuo Kodama,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 377,No. 2,p. 413-418,2008年12月
  • A Novel Technology to Prevent Proarrhythmia of Myoblast Transplantation: "Patterning" of Cell Alignment Using Magnetic Nanoparticles,Hiroki Takanari,Jong-Kook Lee,Miwa Keiko,Akira Ito,Hiroyuki Honda,Itsuo Kodama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 118,No. 18,p. S528-S528,2008年10月,研究発表ペーパー・要旨(国際会議)
  • T-type Ca2+ channel blockers prevent cardiac cell hypertrophy through an inhibition of calcineurin-NFAT3 activation as well as L-type Ca2+ channel blockers.,HORIBA Mitsuru,HORIBA Mitsuru,MUTO Takao,UEDA Norihiro,UEDA Norihiro,OPTHOF Tobias,MIWA Keiko,HOJO Mayumi,LEE Jong-kook,KAMIYA Kaichiro,KODAMA Itsuo,YASUI Kenji,Life Sciences,Vol. 82,No. 11-12,p. 554-560,2008年
  • Long-term amiodarone treatment causes cardioselective hypothyroid-like alteration in gene expression profile,Rong-qian Shi,Jong-Kook Lee,Yoshitaka Hayashi,Yoko Takeuchi,Fukushi Kambe,Sugiko Futaki,Hisao Seo,Yoshiharu Murata,Itsuo Kodama,EUROPEAN JOURNAL OF PHARMACOLOGY,ELSEVIER SCIENCE BV,Vol. 578,No. 2-3,p. 270-278,2008年01月
  • Long-term amiodarone treatment causes cardioselective hypothyroid-like alteration in gene expression profile,Rong-qian Shi,Jong-Kook Lee,Yoshitaka Hayashi,Yoko Takeuchi,Fukushi Kambe,Sugiko Futaki,Hisao Seo,Yoshiharu Murata,Itsuo Kodama,EUROPEAN JOURNAL OF PHARMACOLOGY,ELSEVIER SCIENCE BV,Vol. 578,No. 2-3,p. 270-278,2008年01月
  • Engineering of functional cardiac pacemaker sheets by patterning of cell arrangement using magnetic nanoparticles,Jong-Kook Lee,Hirotoshi Yasui,Hiroaki Hiraiwa,Kazunori Shimizu,Akira Ito,Hiroyuki Honda,Itsuo Kodama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 116,No. 16,p. 118-118,2007年10月,研究発表ペーパー・要旨(国際会議)
  • Sema3a maintains normal heart rhythm through sympathetic innervation patterning,Masaki Ieda,Hideaki Kanazawa,Kensuke Kimura,Fumiyuki Hattori,Yasuyo Ieda,Masahiko Taniguchi,Jong-Kook Lee,Keisuke Matsumura,Yuichi Tomita,Shunichiro Miyoshi,Kouji Shimoda,Shinji Makino,Motoaki Sano,Itsuo Kodama,Satoshi Ogawa,Keiichi Fukuda,NATURE MEDICINE,NATURE PUBLISHING GROUP,Vol. 13,No. 5,p. 604-612,2007年05月
  • Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain,Liyan Zhang,Yoko Sato,Tara Hessa,Gunnar von Heijne,Jong-Kook Lee,Itsuo Kodama,Masao Sakaguchi,Nobuyuki Uozumi,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 104,No. 20,p. 8263-8268,2007年05月
  • Sema3a maintains normal heart rhythm through sympathetic innervation patterning,Masaki Ieda,Hideaki Kanazawa,Kensuke Kimura,Fumiyuki Hattori,Yasuyo Ieda,Masahiko Taniguchi,Jong-Kook Lee,Keisuke Matsumura,Yuichi Tomita,Shunichiro Miyoshi,Kouji Shimoda,Shinji Makino,Motoaki Sano,Itsuo Kodama,Satoshi Ogawa,Keiichi Fukuda,NATURE MEDICINE,NATURE PUBLISHING GROUP,Vol. 13,No. 5,p. 604-612,2007年05月
  • Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain,Liyan Zhang,Yoko Sato,Tara Hessa,Gunnar von Heijne,Jong-Kook Lee,Itsuo Kodama,Masao Sakaguchi,Nobuyuki Uozumi,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 104,No. 20,p. 8263-8268,2007年05月
  • Construction of multi-layered cardiomyocyte sheets using magnetite nanoparticles and magnetic force,Kazunori Shimizu,Akira Ito,Jong-Kook Lee,Tatsuro Yoshida,Keiko Miwa,Hisaaki Ishiguro,Yasushi Numaguchi,Toyoaki Murohara,Itsuo Kodama,Hiroyuki Honda,BIOTECHNOLOGY AND BIOENGINEERING,JOHN WILEY & SONS INC,Vol. 96,No. 4,p. 803-809,2007年03月
  • Construction of multi-layered cardiomyocyte sheets using magnetite nanoparticles and magnetic force,Kazunori Shimizu,Akira Ito,Jong-Kook Lee,Tatsuro Yoshida,Keiko Miwa,Hisaaki Ishiguro,Yasushi Numaguchi,Toyoaki Murohara,Itsuo Kodama,Hiroyuki Honda,BIOTECHNOLOGY AND BIOENGINEERING,JOHN WILEY & SONS INC,Vol. 96,No. 4,p. 803-809,2007年03月
  • 「Aldosterone Modulates If Current Through Gene Expression in Cultured Neonatal Rat Ventricular Myocytes」,Takao Muto,Norihiro Ueda,Tobias Opthof,Tomoko Ohkusa,Kohzo Nagata,Shinsuke Suzuki,Yukiomi Tsuji,Mitsuru Horiba,Jong-Kook Lee,Haruo Honjo,Kaichiro Kamiya,Itsuo Kodama,Kenji Yasui,American Journal of Physiology Heart and Circulatory Physiology,Vol. 293,No. 5,p. 2710-2718,2007年
  • Stem cell therapy -房室結節の修飾、病的心房筋への細胞治療の展望- (特集「心房細動のbest strategy」 小川聡編),Heart View,Vol. 11,No. 7,p. 128-133,2007年
  • 再生心筋を用いた徐脈性不整脈治療(特集「心筋再生にむけた研究基盤」 福田恵一編),分子心血管病,Vol. 8,No. 3,p. 42-47,2007年
  • Midkine possesses a potent angiogenetic action through activation of Akt and ERK,Mitsuru Horiba,Asuka Takahashi,Hiroharu Takenaka,Arihiro Sumida,Hisaaki Ishiguro,Jong-Kook Lee,Itsuo Kodama,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 41,No. 6,p. 1058-1058,2006年12月,研究発表ペーパー・要旨(国際会議)
  • Effects of aldosterone on the gap junction channel protein connexin43 in neonatal rat ventricular myocytes,Shinsuke Suzuki,Tomoko Ohkusa,Takashi Sato,Kenji Yasui,Jong-Kook Lee,Itsuo Komada,Masunori Matsuzaki,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 41,No. 6,p. 1062-1063,2006年12月,研究発表ペーパー・要旨(国際会議)
  • 培養心筋細胞のCa動態と電気活動の同時計測,尾崎友彦,高山祐三,倉島利明,森本晃司,LEE Jong‐Kook,児玉逸雄,小林英津子,佐久間一郎,神保泰彦,電気学会医用・生体工学研究会資料,Vol. MBE-06,No. 51-74,p. 1-4-4,2006年11月17日
  • 培養心筋細胞のCa動態と電気活動の同時計測,尾崎友彦,高山祐三,倉島利明,森本晃司,LEE Jong‐Kook,児玉逸雄,小林英津子,佐久間一郎,神保泰彦,生体・生理工学シンポジウム論文集,Vol. 21st,No. 51,p. 115-118-4,2006年11月17日
  • Midkine possesses a potent angiogenetic action through activation of akt and ERK,Asuka Takahashi,Mitsuru Horiba,Jong-Kook Lee,Hiroharu Takenaka,Kenji Kadomatsu,Itsuo Kodama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 18,p. 298-298,2006年10月,研究発表ペーパー・要旨(国際会議)
  • Effects of aldosterone on the gap junction channel protein connexin43 in neonatal rat ventricular myocytes,Shinsuke Suzuki,Tomoko Ohkusa,Takashi Sato,Kenji Yasui,Jong-Kook Lee,Itsuo Kodama,Masunori Matsuzaki,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 12,No. 8,p. S165-S165,2006年10月,研究発表ペーパー・要旨(国際会議)
  • Aldosterone modulates gap junction remodeling in cultured rat ventricular myocytes,Shinsuke Suzuki,Tomoko Ohkusa,Takashi Sato,Jong-Kook Lee,Kenji Yasui,Itsuo Kodama,Masunori Matsuzaki,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 18,p. 90-90,2006年10月,研究発表ペーパー・要旨(国際会議)
  • Midkine plays a protective role against cardiac ischemia/reperfusion injury through a reduction of apoptotic reaction,Mitsuru Horiba,Kenji Kadomatsu,Kenji Yasui,Jong-Kook Lee,Hiroharu Takenaka,Arihiro Sumida,Kaichiro Kamiya,Sen Chen,Sadatoshi Sakuma,Takashi Muramatsu,Itsuo Kodama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 16,p. 1713-1720,2006年10月
  • Midkine plays a protective role against cardiac ischemia/reperfusion injury through a reduction of apoptotic reaction,Mitsuru Horiba,Kenji Kadomatsu,Kenji Yasui,Jong-Kook Lee,Hiroharu Takenaka,Arihiro Sumida,Kaichiro Kamiya,Sen Chen,Sadatoshi Sakuma,Takashi Muramatsu,Itsuo Kodama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 16,p. 1713-1720,2006年10月
  • Midkine improves the long-term survival of mice after myocardial infarction by reducing the ventricular remodeling,M Horiba,H Takenaka,JK Lee,K Kadomatsu,Kodama, I,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 11,No. 9,p. S280-S280,2005年12月,研究発表ペーパー・要旨(国際会議)
  • Gap junction remodeling and new upstream approach for the treatment of arrhythmias by modulating renin-angiotensin-aldosteron system,T Ohkusa,T Sato,S Suzuki,N Inoue,JK Lee,H Honjo,K Yasui,Kodama, I,M Matsuzaki,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 11,No. 9,p. S247-S247,2005年12月,研究発表ペーパー・要旨(国際会議)
  • Biological repair of chronic complete atrio-ventricular block by transplantation of embryonic stem cell-derived cardiac myocytes,JK Lee,K Hidaka,D Yuasa,M Kado,K Miwa,M Horiba,T Morisaki,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 112,No. 17,p. U277-U277,2005年10月,研究発表ペーパー・要旨(国際会議)
  • Midkine improves the long-term survival of mice after myocardial infarction by reducing the ventricular remodeling,H Takenaka,M Horiba,JK Lee,K Kadomatu,Y Ueda,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 112,No. 17,p. U337-U337,2005年10月,研究発表ペーパー・要旨(国際会議)
  • Decreased vagal control over heart rate in rats with right-sided congestive heart failure - Downregulation of neuronal nitric oxide synthase,M Nihei,JK Lee,H Honjo,K Yasui,M Uzzaman,K Kamiya,T Opthof,Kodama, I,CIRCULATION JOURNAL,JAPANESE CIRCULATION SOCIETY,Vol. 69,No. 4,p. 493-499,2005年04月
  • Decreased vagal control over heart rate in rats with right-sided congestive heart failure - Downregulation of neuronal nitric oxide synthase,M Nihei,JK Lee,H Honjo,K Yasui,M Uzzaman,K Kamiya,T Opthof,Kodama, I,CIRCULATION JOURNAL,JAPANESE CIRCULATION SOCIETY,Vol. 69,No. 4,p. 493-499,2005年04月
  • Involvement of Ca2+ regulatory proteins in lethal arrhythmias,T Ohkusa,N Inoue,T Sato,JK Lee,Kodama, I,M Matsuzaki,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 97,p. 26P-26P,2005年,研究発表ペーパー・要旨(国際会議)
  • A novel mouse model of sudden cardiac death with acquired long QT and Torsade de Pointes secondary to complete AV block,JK Lee,D Yuasa,M Iwase,M Hayashi,M Horiba,Kodama, I,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 88,No. 1,p. 472A-472A,2005年01月,研究発表ペーパー・要旨(国際会議)
  • Subtype switching of L-type Ca2+ channel from Cav1.3 to Cav1.2 in embryonic murine ventricle.,TAKEMURA Haruki,YASUI Kenji,OPTHOF Tobias,OPTHOF Tobias,NIWA Noriko,HORIBA Mitsuru,SHIMIZU Atsuya,LEE Jong-kook,HONJO Haruo,KAMIYA Kaichiro,UEDA Yuichi,KODAMA Itsuo,Circulation Journal,Vol. 69,No. 11,p. 1405-1411,2005年
  • Pathophysiological significance of T-type Ca2+ channels: expression of T-type Ca2+ channels in fetal and diseased heart.,Kenji Yasui,Noriko Niwa,Haruki Takemura,Tobias Opthof,Takao Muto,Mitsuru Horiba,Atsuya Shimizu,Jong-Kook Lee,Haruo Honjo,Kaichiro Kamiya,Itsuo Kodama,J Pharmacol Sci,Vol. 99,No. 3,p. 205-210,2005年
  • 不整脈の遺伝子・細胞治療.(不整脈研究の新たな展開-混乱からの再出発- 児玉逸雄編),Current Therapy,Vol. 23,No. 3,p. 21-26,2005年
  • 「バイオペースメーカ」の創生,ICUとCCU,Vol. 29,No. 7,p. 547-552,2005年
  • 不整脈病態におけるゲノミクス.,最新医学,Vol. 60,No. 10,p. 2286-2293,2005年
  • 31) ES細胞から心筋細胞への分化 : 血管内皮細胞由来paracrine因子による効果(第123回日本循環器学会東海地方会),李 鍾国,三輪 佳子,児玉 逸雄,日高 京子,森崎 隆幸,石黒 久晶,室原 豊明,角 三和子,上田 祐一,Circulation journal : official journal of the Japanese Circulation Society,社団法人日本循環器学会,Vol. 68,No. 0,2004年10月20日
  • Gene profiling in a novel mouse model of sudden cardiac death with acquired QT prolongation and Torsades de Pointes secondary to complete AV block,JK Lee,D Yuasa,M Iwase,M Hayashi,H Ishiguro,M Horiba,K Yasui,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 110,No. 17,p. 98-98,2004年10月,研究発表ペーパー・要旨(国際会議)
  • Midkine plays a protective role against cardiac ischemia/reperfusion injury through a reduction of apoptotic reaction,M Horiba,K Yasui,JK Lee,K Kadomatsu,T Muramatsu,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 110,No. 17,p. 106-106,2004年10月,研究発表ペーパー・要旨(国際会議)
  • Remodeling of T3-responsive gene transcription in rat hearts by chronic amiodarone,RQ Shi,JK Lee,Y Takeuchi,M Horiba,F Kambe,H Seo,Y Murata,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 110,No. 17,p. 99-99,2004年10月,研究発表ペーパー・要旨(国際会議)
  • Rapid electrical stimulation of contraction modulates gap junction protein in neonatal rat cultured cardiomyocytes - Involvement of mitogen-activated protein kinases and effects of angiotensin II-receptor antagonist,N Inoue,T Ohkusa,T Nao,JK Lee,T Matsumoto,Y Hisamatsu,T Satoh,M Yano,K Yasui,Kodama, I,M Matsuzaki,JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,ELSEVIER SCIENCE INC,Vol. 44,No. 4,p. 914-922,2004年08月
  • Rapid electrical stimulation of contraction modulates gap junction protein in neonatal rat cultured cardiomyocytes - Involvement of mitogen-activated protein kinases and effects of angiotensin II-receptor antagonist,N Inoue,T Ohkusa,T Nao,JK Lee,T Matsumoto,Y Hisamatsu,T Satoh,M Yano,K Yasui,Kodama, I,M Matsuzaki,JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,ELSEVIER SCIENCE INC,Vol. 44,No. 4,p. 914-922,2004年08月
  • Ionic and molecular mechanisms of acquired QT prolongation in association with complete atrioventricular block,Kodama, I,Y Tsuji,T Opthof,K Yasui,JK Lee,S Nattel,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 37,No. 1,p. 311-312,2004年07月,研究発表ペーパー・要旨(国際会議)
  • Developmental changes of Ni2+ sensitivity and automaticity in Nkx2.5-positive cardiac precursor cells from murine embryonic stem cell,K Manabe,J Miake,N Sasaki,H Furuichi,S Yano,E Mizuta,Y Yamamoto,Y Hoshikawa,H Yamazaki,F Tajima,G Shiota,E Nanba,S Ohgi,K Hidaka,T Morisaki,Y Kurata,JK Lee,O Igawa,C Shigemasa,Hisatome, I,CIRCULATION JOURNAL,BLACKWELL PUBLISHING ASIA,Vol. 68,No. 7,p. 724-726,2004年07月
  • Developmental changes of Ni2+ sensitivity and automaticity in Nkx2.5-positive cardiac precursor cells from murine embryonic stem cell,K Manabe,J Miake,N Sasaki,H Furuichi,S Yano,E Mizuta,Y Yamamoto,Y Hoshikawa,H Yamazaki,F Tajima,G Shiota,E Nanba,S Ohgi,K Hidaka,T Morisaki,Y Kurata,JK Lee,O Igawa,C Shigemasa,Hisatome, I,CIRCULATION JOURNAL,BLACKWELL PUBLISHING ASIA,Vol. 68,No. 7,p. 724-726,2004年07月
  • Ca(v)3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period,N Niwa,K Yasui,T Opthof,H Takemura,A Shimizu,M Horiba,JK Lee,H Honjo,K Kamiya,Kodama, I,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 286,No. 6,p. H2257-H2263,2004年06月
  • Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression,K Takeshita,T Fujimori,Y Kurotaki,H Honjo,H Tsujikawa,K Yasui,JK Lee,K Kamiya,K Kitaichi,K Yamamoto,M Ito,T Kondo,S Iino,Y Inden,M Hirai,T Murohara,Kodama, I,Y Nabeshima,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 109,No. 14,p. 1776-1782,2004年04月
  • Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression,K Takeshita,T Fujimori,Y Kurotaki,H Honjo,H Tsujikawa,K Yasui,JK Lee,K Kamiya,K Kitaichi,K Yamamoto,M Ito,T Kondo,S Iino,Y Inden,M Hirai,T Murohara,Kodama, I,Y Nabeshima,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 109,No. 14,p. 1776-1782,2004年04月
  • Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction,LY Zhang,JK Lee,SA John,N Uozumi,Kodama, I,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 279,No. 8,p. 7037-7047,2004年02月
  • Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction,LY Zhang,JK Lee,SA John,N Uozumi,Kodama, I,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 279,No. 8,p. 7037-7047,2004年02月
  • 研究会 第38回理論心電図研究会 完全房室ブロックに伴うリモデリングと心室性不整脈,辻 幸臣,児玉 逸雄,Nattel Stanley,安井 健二,因田 恭也,竹村 春起,丹羽 統子,盧 智波,李 鍾国,本荘 晴朗,神谷 香一郎,心臓,心臓,Vol. 36,No. 5,p. 407-412,2004年
  • 再生心筋の電気生理.(特集:動き出す心筋創生),分子心血管病,Vol. 5,No. 3,p. 58-63,2004年
  • 電気的リモデリングとは?(慢性心不全のNew Frontier –from bench to bedside- 松崎益徳編),Heart View,Vol. 9,No. 2,p. 101-107,2004年
  • Rapid electrical stimulation upregulates gap-junction protein and modulates conduction properties of cultured cardiomyocytes,N Inoue,T Ohkusa,T Nao,JK Lee,T Matsumoto,Y Hisamatsu,T Sato,M Yano,K Yasui,Kodama, I,M Matsuzaki,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 108,No. 17,p. 291-291,2003年10月,研究発表ペーパー・要旨(国際会議)
  • Endogenous expression of TIMP-1 regulates development of experimental abdominal aortic aneurysms independent of interactions with gelatinase B,JK Lee,C Buckley,M Borhani,TL Ennis,RW Thompson,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 108,No. 17,p. 166-166,2003年10月,研究発表ペーパー・要旨(国際会議)
  • Overexpression of calpastatin by gene transfer prevents troponin I degradation and ameliorates contractile dysfunction in rat hearts subjected to ischemia/reperfusion,A Maekawa,JK Lee,T Nagaya,K Kamiya,K Yasui,M Horiba,K Miwa,M Uzzaman,M Maki,Y Ueda,Kodama, I,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 35,No. 10,p. 1277-1284,2003年10月
  • Overexpression of calpastatin by gene transfer prevents troponin I degradation and ameliorates contractile dysfunction in rat hearts subjected to ischemia/reperfusion,A Maekawa,JK Lee,T Nagaya,K Kamiya,K Yasui,M Horiba,K Miwa,M Uzzaman,M Maki,Y Ueda,Kodama, I,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 35,No. 10,p. 1277-1284,2003年10月
  • Mechanosensitivity of G protein-activated inwardly rectifying K+ (GIRK) channels depends on channel-PIP2 interactions through the activation of PKC,LY Zhang,JK Lee,SA John,N Uozumi,Kodama, I,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 84,No. 2,p. 225A-225A,2003年02月,研究発表ペーパー・要旨(国際会議)
  • Subtype switching of T-type Ca2+ channel gene in mouse heart from early embryo to adulthood,N Niwa,JK Lee,K Yasui,Kodama, I,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 84,No. 2,p. 330A-330A,2003年02月,研究発表ペーパー・要旨(国際会議)
  • Electrophysiological differentiation of cardiac myocytes derived from Nkx2.5-GFP knock-in murine embryonic stem cell,JK Lee,K Hidaka,K Miwa,RQ Shi,T Morisaki,Kodama, I,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 84,No. 2,p. 425A-425A,2003年02月,研究発表ペーパー・要旨(国際会議)
  • Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells,K Hidaka,JK Lee,HS Kim,CH Ihm,A Iio,M Ogawa,SI Nishikawa,Kodama, I,T Morisaki,FASEB JOURNAL,FEDERATION AMER SOC EXP BIOL,Vol. 17,No. 2,p. 740-+,2003年02月
  • Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells,K Hidaka,JK Lee,HS Kim,CH Ihm,A Iio,M Ogawa,SI Nishikawa,Kodama, I,T Morisaki,FASEB JOURNAL,FEDERATION AMER SOC EXP BIOL,Vol. 17,No. 2,p. 740-+,2003年02月
  • ポストゲノム時代の不整脈治療:(1) 遺伝子導入による不整脈治療は可能か?(不整脈:新しい内科と外科の接点 磯部光章編),Cardiovascular Med-Surg,Vol. 5,No. 2,p. 91-98,2003年
  • Cardiac myocytes derived from Nkx2.5-GFP knock-in murine embryonic stem cell: Electrophysiological differentiation and feasibility of transplantation,JK Lee,K Hidaka,K Miwa,RQ Shi,LY Zhang,T Morisaki,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 68-68,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Unexpectedly early death of klotho mice, a human aging model, is associated with a failure of autonomic response of heart rate,K Takeshita,T Kondo,K Yasui,JK Lee,S Iino,M Hirai,H Honjo,K Kamiya,Kodama, I,T Fujimori,Y Nabeshima,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 152-152,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Vagal control on heart rate is augmented at sinoatrial node despite the attenuation at pre- and post-ganglionic level in rat with right ventricular heart failure,M Nihei,JK Lee,H Honjo,K Kamiya,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 111-111,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block,Y Tsuji,T Opthof,K Yasui,Y Inden,H Takemura,N Niwa,ZB Lu,JK Lee,H Honjo,K Kamiya,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 15,p. 2012-2018,2002年10月
  • Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block,Y Tsuji,T Opthof,K Yasui,Y Inden,H Takemura,N Niwa,ZB Lu,JK Lee,H Honjo,K Kamiya,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 15,p. 2012-2018,2002年10月
  • Modulation of spontaneous activity in mouse ventricular myocytes by adenovirus-mediated gene transfer of Kir2.2 channels,T Hibino,J Lee,K Miwa,L Zhang,Kodama, I,EUROPEAN HEART JOURNAL,W B SAUNDERS CO LTD,Vol. 23,p. 42-42,2002年08月,研究発表ペーパー・要旨(国際会議)
  • Developmental changes of Ca2+ handling in mouse ventricular cells from early embryo to adulthood,WR Liu,K Yasui,T Opthof,R Ishiki,JK Lee,K Kamiya,M Yokota,Kodama, I,LIFE SCIENCES,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 71,No. 11,p. 1279-1292,2002年08月
  • Developmental changes of Ca2+ handling in mouse ventricular cells from early embryo to adulthood,WR Liu,K Yasui,T Opthof,R Ishiki,JK Lee,K Kamiya,M Yokota,Kodama, I,LIFE SCIENCES,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 71,No. 11,p. 1279-1292,2002年08月
  • 遺伝子導入による心筋電気特性の制御-不整脈の遺伝子治療は可能か?(不整脈研究の新しい潮流 -不整脈の臨床と治療法に関する新しい展開 平岡昌康編),医学のあゆみ.,Vol. 200,No. 9,p. 769-774,2002年
  • Ionic mechanisms of acquired QT prolongation and Torsades de Pointes in rabbits with chronic complete atrioventricular block,Y Tsuji,T Opthof,Y Inden,K Yasui,ZB Lu,JK Lee,K Kamiya,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 104,No. 17,p. 24-25,2001年10月,研究発表ペーパー・要旨(国際会議)
  • Genomic induction of cardiac hypothyroidism: A novel approach to prevent life-threatening arrhythmias,JK Lee,Y Hayashi,K Miwa,L Zhang,H Seo,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 104,No. 17,p. 46-46,2001年10月,研究発表ペーパー・要旨(国際会議)
  • I-f current and spontaneous activity in mouse embryonic ventricular myocytes,K Yasui,WR Liu,T Opthof,K Kada,JK Lee,K Kamiya,Kodama, I,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 88,No. 5,p. 536-542,2001年03月
  • I-f current and spontaneous activity in mouse embryonic ventricular myocytes,K Yasui,WR Liu,T Opthof,K Kada,JK Lee,K Kamiya,Kodama, I,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 88,No. 5,p. 536-542,2001年03月
  • Stretch-induced inhibition of G protein-activated K+ channels is mediated through the activation of protein kinase C,LY Zhang,JK Lee,SA John,Kodama, I,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 80,No. 1,p. 622A-622A,2001年01月,研究発表ペーパー・要旨(国際会議)
  • Inward rectification in Kir2.1: Voltage-dependent interaction between polyamine block and intrinsic gating,LH Xie,SA John,JK Lee,L Yang,JN Weiss,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 80,No. 1,p. 628A-628A,2001年01月,研究発表ペーパー・要旨(国際会議)
  • Residues and mechanisms for slow activation and Ba2+ block of the cardiac muscarinic K+ channel, Kir3.1/Kir3.4,MK Lancaster,KM Dibb,CC Quinn,R Leach,JK Lee,JBC Findlay,MR Boyett,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 275,No. 46,p. 35831-35839,2000年11月
  • Residues and mechanisms for slow activation and Ba2+ block of the cardiac muscarinic K+ channel, Kir3.1/Kir3.4,MK Lancaster,KM Dibb,CC Quinn,R Leach,JK Lee,JBC Findlay,MR Boyett,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 275,No. 46,p. 35831-35839,2000年11月
  • Developmental change of hyperpolarization-activated inward current (I-f) in mouse embryonic ventricular cells and the identification of the HCN gene subtype,K Yasui,W Liu,T Opthof,K Kada,JK Lee,K Kamiya,Kodama, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 102,No. 18,p. 262-262,2000年10月,研究発表ペーパー・要旨(国際会議)
  • Cell-to-cell interaction prevents cell death in cultured neonatal rat ventricular myocytes,K Yasui,K Kada,M Hojo,JK Lee,K Kamiya,J Toyama,T Opthof,Kodama, I,CARDIOVASCULAR RESEARCH,ELSEVIER SCIENCE BV,Vol. 48,No. 1,p. 68-76,2000年10月
  • Cell-to-cell interaction prevents cell death in cultured neonatal rat ventricular myocytes,K Yasui,K Kada,M Hojo,JK Lee,K Kamiya,J Toyama,T Opthof,Kodama, I,CARDIOVASCULAR RESEARCH,ELSEVIER SCIENCE BV,Vol. 48,No. 1,p. 68-76,2000年10月
  • Slow activation of the cardiac muscarinic K+ channel Kir3.1-Kir3.4 is due to polyamines unbinding from charged sites within the channel pore,MK Lancaster,KM Dibb,R Leach,JK Lee,JBC Findlay,MR Boyett,JOURNAL OF PHYSIOLOGY-LONDON,CAMBRIDGE UNIV PRESS,Vol. 527,p. 117P-117P,2000年09月,研究発表ペーパー・要旨(国際会議)
  • Hyperpolarization-activated inward current (If) in early-stage embryonic mouse ventricular myocytes: Does early pacemaker activity originate in the ventricle?,K Yasui,W Liu,T Opthof,K Kada,JK Lee,K Kamiya,Kodama, I,EUROPEAN HEART JOURNAL,W B SAUNDERS CO LTD,Vol. 21,p. 64-64,2000年08月,研究発表ペーパー・要旨(国際会議)
  • A novel approach to regulate cardiac cell excitability by gene transfer of thyroid hormone receptors.,JK Lee,Y Hayashi,L Zhang,H Seo,Kodama, I,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 78,No. 1,p. 223A-223A,2000年01月,研究発表ペーパー・要旨(国際会議)
  • 抗不整脈薬の電気生理-心筋細胞イオンチャネルとそのモジュレーター,目で見る循環器病シリーズ1- 不整脈. 笠貫 宏 編.,p. 31-47,2000年
  • 循環器内科医のための薬理学(4):Kチャネル抑制クラスⅢ薬、アミオダロン.,心臓,Vol. 32,No. 4,p. 291-297,2000年
  • チャネルサブタイプ‐薬剤選択にどのように活かすか」(特集:Sicilian Gambitの臨床応用),Mebio,Vol. 17,p. 61-69,2000年
  • Downregulation of voltage-gated K+ channels in rat heart with right ventricular hypertrophy,JK Lee,A Nishiyama,F Kambe,H Seo,S Takeuchi,K Kamiya,Kodama, I,J Toyama,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 277,No. 5,p. H1725-H1731,1999年11月
  • Downregulation of voltage-gated K+ channels in rat heart with right ventricular hypertrophy,JK Lee,A Nishiyama,F Kambe,H Seo,S Takeuchi,K Kamiya,Kodama, I,J Toyama,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 277,No. 5,p. H1725-H1731,1999年11月
  • Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1,JK Lee,SA John,JN Weiss,JOURNAL OF GENERAL PHYSIOLOGY,ROCKEFELLER UNIV PRESS,Vol. 113,No. 4,p. 555-563,1999年04月
  • Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1,JK Lee,SA John,JN Weiss,JOURNAL OF GENERAL PHYSIOLOGY,ROCKEFELLER UNIV PRESS,Vol. 113,No. 4,p. 555-563,1999年04月
  • Interaction of polyamines and polyamine toxins reveals a novel gating mechanism in Kir2.1 channels,JK Lee,SA John,JN Weiss,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 76,No. 1,p. A415-A415,1999年01月,研究発表ペーパー・要旨(国際会議)
  • 病態におけるチャネルのリモデリング,医学の歩み,Vol. 189,No. 5,p. 271-276,1999年
  • Specific membrane cysteine residues modulate the pH sensitivity of intrinsic gating in Kir2.1 channels,JK Lee,SA John,JN Weiss,BIOPHYSICAL JOURNAL,BIOPHYSICAL SOCIETY,Vol. 74,No. 2,p. A116-A116,1998年02月,研究発表ペーパー・要旨(国際会議)
  • Vesnarinone prolongs action potential duration without reverse frequency dependence in rabbit ventricular muscle by blocking the delayed rectifier K+ current,J Toyama,K Kamiya,JH Cheng,JK Lee,R Suzuki,Kodama, I,CIRCULATION,AMER HEART ASSOC,Vol. 96,No. 10,p. 3696-3703,1997年11月
  • Vesnarinone prolongs action potential duration without reverse frequency dependence in rabbit ventricular muscle by blocking the delayed rectifier K+ current,J Toyama,K Kamiya,JH Cheng,JK Lee,R Suzuki,Kodama, I,CIRCULATION,AMER HEART ASSOC,Vol. 96,No. 10,p. 3696-3703,1997年11月
  • Polyamines cause inward rectification in Kir2.1 (IRK1) channels by forming a tethered blocking particle with an intrinsic gate,JK Lee,SA John,YJ Lu,JN Weiss,CIRCULATION,AMER HEART ASSOC,Vol. 96,No. 8,p. 2382-2382,1997年10月,研究発表ペーパー・要旨(国際会議)
  • Stage-dependent changes in membrane currents in rats with monocrotaline-induced right ventricular hypertrophy,JK Lee,Kodama, I,H Honjo,T Anno,K Kamiya,J Toyama,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 272,No. 6,p. H2833-H2842,1997年06月
  • Stage-dependent changes in membrane currents in rats with monocrotaline-induced right ventricular hypertrophy,JK Lee,Kodama, I,H Honjo,T Anno,K Kamiya,J Toyama,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 272,No. 6,p. H2833-H2842,1997年06月
  • The intrinsic gating mechanism is fundamental to inward rectification in the IRK1 channel.,JK Lee,SA John,Y Lu,RC Shieh,JN Weiss,BIOPHYSICAL JOURNAL,CELL PRESS,Vol. 72,No. 2,p. WPO21-WPO21,1997年02月,研究発表ペーパー・要旨(国際会議)
  • Inward rectification of the IRK1 channel expressed in Xenopus oocytes: Effects of intracellular pH reveal an intrinsic gating mechanism,RC Shieh,SA John,JK Lee,JN Weiss,JOURNAL OF PHYSIOLOGY-LONDON,CAMBRIDGE UNIV PRESS,Vol. 494,No. 2,p. 363-376,1996年07月
  • Inward rectification of the IRK1 channel expressed in Xenopus oocytes: Effects of intracellular pH reveal an intrinsic gating mechanism,RC Shieh,SA John,JK Lee,JN Weiss,JOURNAL OF PHYSIOLOGY-LONDON,CAMBRIDGE UNIV PRESS,Vol. 494,No. 2,p. 363-376,1996年07月
  • Evidence for an intrinsic pH-sensitive mechanism of inward rectification of the inward rectifier K channel IRK1.,RC Shieh,SA John,JK Lee,JN Weiss,BIOPHYSICAL JOURNAL,CELL PRESS,Vol. 70,No. 2,p. TUP71-TUP71,1996年02月,研究発表ペーパー・要旨(国際会議)
  • LOW-DOSES OF VESNARINONE DECREASE BOTH POTASSIUM AND CALCIUM CURRENTS IN VENTRICULAR CELLS,JK LEE,KODAMA, I,R SUZUKI,K KAMIYA,J TOYAMA,CIRCULATION,AMER HEART ASSOC,Vol. 92,No. 8,p. 2888-2888,1995年10月,研究発表ペーパー・要旨(国際会議)
  • STAGE-DEPENDENT CHANGES OF MEMBRANE CURRENTS IN RAT VENTRICULAR MYOCYTES ASSOCIATED WITH MYOCARDIAL HYPERTROPHY,JK LEE,KODAMA, I,H HONJO,K KAMIYA,J TOYAMA,CIRCULATION,AMER HEART ASSOC,Vol. 92,No. 8,p. 2747-2747,1995年10月,研究発表ペーパー・要旨(国際会議)
  • COMPLEX FREQUENCY-DEPENDENT INTERACTION OF CLASS-I ANTIARRHYTHMIC DRUGS AS THEY AFFECT INTRAVENTRICULAR-CONDUCTION,JK LEE,C TAKANAKA,M NONOKAWA,H KATO,S YABE,KODAMA, I,J TOYAMA,EUROPEAN HEART JOURNAL,W B SAUNDERS CO LTD,Vol. 16,No. 6,p. 832-841,1995年06月
  • COMPLEX FREQUENCY-DEPENDENT INTERACTION OF CLASS-I ANTIARRHYTHMIC DRUGS AS THEY AFFECT INTRAVENTRICULAR-CONDUCTION,JK LEE,C TAKANAKA,M NONOKAWA,H KATO,S YABE,KODAMA, I,J TOYAMA,EUROPEAN HEART JOURNAL,W B SAUNDERS CO LTD,Vol. 16,No. 6,p. 832-841,1995年06月
  • FREQUENCY-DEPENDENT EFFECTS OF CLASS-I ANTIARRHYTHMIC AGENTS STUDIED IN PATIENTS WITH IMPLANTED PACEMAKERS,C TAKANAKA,JK LEE,M NONOKAWA,T SUGIYAMA,S YAME,PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY,FUTURA PUBL CO,Vol. 17,No. 11,p. 2100-2105,1994年11月
  • FREQUENCY-DEPENDENT EFFECTS OF CLASS-I ANTIARRHYTHMIC AGENTS STUDIED IN PATIENTS WITH IMPLANTED PACEMAKERS,C TAKANAKA,JK LEE,M NONOKAWA,T SUGIYAMA,S YAME,PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY,FUTURA PUBL CO,Vol. 17,No. 11,p. 2100-2105,1994年11月

著書

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