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Takeshi Onuma

小沼 健

Graduate School of Science Department of Biological Sciences, Assistant Professor

keyword house,3D morphogenesis,Left-right asymmetry,DNAi,tadpole body,Developmental Biology,chordate,appendicularian,gene screening,live imaging

Research Areas

  • Life sciences, Cell biology
  • Life sciences, Developmental biology

Papers

  • Mouth opening is mediated by separation of dorsal and ventral daughter cells of the lip precursor cells in the larvacean, Oikopleura dioica., Ryo Morita,Takeshi A Onuma,Lucia Manni,Nobuhiko Ohno,Hiroki Nishida, Development genes and evolution, 2020/08/15
  • A genome database for a Japanese population of the larvacean Oikopleura dioica., Kai Wang,Ryo Tomura,Wei Chen,Miho Kiyooka,Hinako Ishizaki,Tomoyuki Aizu,Yohei Minakuchi,Masahide Seki,Yutaka Suzuki,Tatsuya Omotezako,Ritsuko Suyama,Aki Masunaga,Charles Plessy,Nicholas M Luscombe,Christelle Dantec,Patrick Lemaire,Takehiko Itoh,Atsushi Toyoda,Hiroki Nishida,Takeshi A Onuma, Development, growth & differentiation, Vol. 62, No. 6, p. 450-461, 2020/08
  • Protein phosphatase 2A is essential to maintain meiotic arrest, and to prevent Ca2+ burst at spawning and eventual parthenogenesis in the larvacean Oikopleura dioica., Masaki Matsuo,Takeshi A Onuma,Tatsuya Omotezako,Hiroki Nishida, Developmental biology, Vol. 460, No. 2, p. 155-163, 2020/04/15
  • A chordate species lacking Nodal utilizes calcium oscillation and Bmp for left-right patterning., Takeshi A Onuma,Momoko Hayashi,Fuki Gyoja,Kanae Kishi,Kai Wang,Hiroki Nishida, Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 8, p. 4188-4198, 2020/02/25
  • ANISEED 2019: 4D exploration of genetic data for an extended range of tunicates., Justine Dardaillon,Delphine Dauga,Paul Simion,Emmanuel Faure,Takeshi A Onuma,Melissa B DeBiasse,Alexandra Louis,Kazuhiro R Nitta,Magali Naville,Lydia Besnardeau,Wendy Reeves,Kai Wang,Marie Fagotto,Marion Guéroult-Bellone,Shigeki Fujiwara,Rémi Dumollard,Michael Veeman,Jean-Nicolas Volff,Hugues Roest Crollius,Emmanuel Douzery,Joseph F Ryan,Bradley Davidson,Hiroki Nishida,Christelle Dantec,Patrick Lemaire, Nucleic acids research, Vol. 48, No. D1, 2020/01/08
  • Mother-to-embryo vitellogenin transport in a viviparous teleost Xenotoca eiseni., Atsuo Iida,Hiroyuki N Arai,Yumiko Someya,Mayu Inokuchi,Takeshi A Onuma,Hayato Yokoi,Tohru Suzuki,Eiichi Hondo,Kaori Sano, Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 44, p. 22359-22365, 2019/10/29
  • Wavy movements of epidermis monocilia drive the neurula rotation that determines left-right asymmetry in ascidian embryos., Shiori Yamada,Yuka Tanaka,Kaoru S Imai,Motohiko Saigou,Takeshi A Onuma,Hiroki Nishida, Developmental biology, Vol. 448, No. 2, p. 173-182, 2019/04/15
  • Modified whole-mount in situ hybridisation and immunohistochemistry protocols without removal of the vitelline membrane in the appendicularian Oikopleura dioica., Takeshi A Onuma,Masaki Matsuo,Hiroki Nishida, Development genes and evolution, SPRINGER, Vol. 227, No. 5, p. 367-374, 2017/09
  • Patterning and morphogenesis of the intricate but stereotyped oikoplastic epidermis of the appendicularian, Oikopleura dioica., Kanae Kishi,Momoko Hayashi,Takeshi A Onuma,Hiroki Nishida, Developmental biology, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 428, No. 1, p. 245-257, 2017/08/01
  • Genome-wide survey of miRNAs and their evolutionary history in the ascidian, Halocynthia roretzi., Kai Wang,Christelle Dantec,Patrick Lemaire,Takeshi A Onuma,Hiroki Nishida, BMC genomics, BIOMED CENTRAL LTD, Vol. 18, No. 1, p. 314-314, 2017/04/20
  • DNA interference-mediated screening of maternal factors in the chordate Oikopleura dioica., Tatsuya Omotezako,Masaki Matsuo,Takeshi A Onuma,Hiroki Nishida, Scientific reports, NATURE PUBLISHING GROUP, Vol. 7, p. 44226-44226, 2017/03/10
  • Internal and external morphology of adults of the appendicularian, Oikopleura dioica: an SEM study., Takeshi A Onuma,Miho Isobe,Hiroki Nishida, Cell and tissue research, SPRINGER, Vol. 367, No. 2, p. 213-227, 2017/02
  • Redundant mechanisms are involved in suppression of default cell fates during embryonic mesenchyme and notochord induction in ascidians., Hitoshi Kodama,Yoshimasa Miyata,Mami Kuwajima,Ryoichi Izuchi,Ayumi Kobayashi,Fuki Gyoja,Takeshi A Onuma,Gaku Kumano,Hiroki Nishida, Developmental biology, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 416, No. 1, p. 162-172, 2016/08/01
  • Maternal and zygotic transcriptomes in the appendicularian, Oikopleura dioica: novel protein-encoding genes, intra-species sequence variations, and trans-spliced RNA leader., Kai Wang,Tatsuya Omotezako,Kanae Kishi,Hiroki Nishida,Takeshi A Onuma, Development genes and evolution, Vol. 225, No. 3, p. 149-59, 2015/06
  • DNA interference: DNA-induced gene silencing in the appendicularian Oikopleura dioica., Tatsuya Omotezako,Takeshi A Onuma,Hiroki Nishida, Proceedings. Biological sciences, Vol. 282, No. 1807, p. 20150435-20150435, 2015/05/22
  • Long-distance cell migration during larval development in the appendicularian, Oikopleura dioica., Kanae Kishi,Takeshi A Onuma,Hiroki Nishida, Developmental biology, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 395, No. 2, p. 299-306, 2014/11/15
  • RNA interference in the appendicularian Oikopleura dioica reveals the function of the Brachyury gene., Tatsuya Omotezako,Atsuo Nishino,Takeshi A Onuma,Hiroki Nishida, Development genes and evolution, Vol. 223, No. 4, p. 261-7, 2013/07
  • Duplicated Kiss1 receptor genes in zebrafish: distinct gene expression patterns, different ligand selectivity, and a novel nuclear isoform with transactivating activity., Takeshi A Onuma,Cunming Duan, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, FEDERATION AMER SOC EXP BIOL, Vol. 26, No. 7, p. 2941-50, 2012/07
  • Regulation of temporal and spatial organization of newborn GnRH neurons by IGF signaling in zebrafish., Takeshi A Onuma,Yonghe Ding,Eytan Abraham,Yonathern Zohar,Hironori Ando,Cunming Duan, The Journal of neuroscience : the official journal of the Society for Neuroscience, SOC NEUROSCIENCE, Vol. 31, No. 33, p. 11814-24, 2011/08/17
  • Expression of GnRH genes is elevated in discrete brain loci of chum salmon before initiation of homing behavior and during spawning migration., Takeshi A Onuma,Keita Makino,Hironori Ando,Masatoshi Ban,Masa-Aki Fukuwaka,Tomonori Azumaya,Akihisa Urano, General and comparative endocrinology, Vol. 168, No. 3, p. 356-68, 2010/09/15
  • Changes in gene expression for GH/PRL/SL family hormones in the pituitaries of homing chum salmon during ocean migration through upstream migration., Takeshi A Onuma,Masatoshi Ban,Keita Makino,Hiroshi Katsumata,WeiWei Hu,Hironori Ando,Masa-aki Fukuwaka,Tomonori Azumaya,Akihisa Urano, General and comparative endocrinology, Vol. 166, No. 3, p. 537-48, 2010/05/01
  • Changes in the plasma levels of insulin-like growth factor-I from the onset of spawning migration through upstream migration in chum salmon., Takeshi A Onuma,Keita Makino,Hiroshi Katsumata,Brian R Beckman,Masatoshi Ban,Hironori Ando,Masa-aki Fukuwaka,Tomonori Azumaya,Penny Swanson,Akihisa Urano, General and comparative endocrinology, Vol. 165, No. 2, p. 237-43, 2010/01/15
  • Elevation of the plasma level of insulin-like growth factor-I with reproductive maturation prior to initiation of spawning migration of chum salmon., Takeshi A Onuma,Keita Makino,Masatoshi Ban,Hironori Ando,Masa-aki Fukuwaka,Tomonori Azumaya,Penny Swanson,Akihisa Urano, Annals of the New York Academy of Sciences, Vol. 1163, p. 497-500, 2009/04
  • Activity of the pituitary-gonadal axis is increased prior to the onset of spawning migration of chum salmon., Takeshi A Onuma,Shunpei Sato,Hiroshi Katsumata,Keita Makino,Weiwei Hu,Aya Jodo,Nancy D Davis,Jon T Dickey,Masatoshi Ban,Hironori Ando,Masa-Aki Fukuwaka,Tomonori Azumaya,Penny Swanson,Akihisa Urano, The Journal of experimental biology, Vol. 212, No. Pt 1, p. 56-70, 2009/01
  • Change of morphology and cytoskeletal protein gene expression during dibutyryl cAMP-induced differentiation in C6 glioma cells., Weiwei Hu,Takeshi Onuma,Naoko Birukawa,Masashi Abe,Etsuro Ito,Zhong Chen,Akihisa Urano, Cellular and molecular neurobiology, Vol. 28, No. 4, p. 519-28, 2008/06
  • Stimulatory effects of insulin-like growth factor 1 on expression of gonadotropin subunit genes and release of follicle-stimulating hormone and luteinizing hormone in masu salmon pituitary cells early in gametogenesis., Shunji Furukuma,Takeshi Onuma,Penny Swanson,Qiong Luo,Nobuhisa Koide,Houji Okada,Akihisa Urano,Hironori Ando, Zoological science, Vol. 25, No. 1, p. 88-98, 2008/01
  • Expression of hormone genes and osmoregulation in homing chum salmon: A minireview, Keita Makino,Takeshi A. Onuma,Takashi Kitahashi,Hironori Ando,Masatoshi Ban,Akihisa Urano, GENERAL AND COMPARATIVE ENDOCRINOLOGY, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 152, No. 2-3, p. 304-309, 2007/06
  • Reproductive stage-related effects of salmon GnRH and sex steroid hormones on expression of genes encoding fushi tarazu factor 1 homolog and estrogen receptor alpha in masu salmon pituitary cells in vitro., Takeshi A Onuma,Hironori Ando,Nobuhisa Koide,Houji Okada,Akihisa Urano, General and comparative endocrinology, Vol. 152, No. 1, p. 64-72, 2007/05/15
  • Effects of salmon GnRH and sex steroid hormones on expression of genes encoding growth hormone/prolactin/somatolactin family hormones and a pituitary-specific transcription factor in masu salmon pituitary cells in vitro., Takeshi Onuma,Hironori Ando,Nobuhisa Koide,Houji Okada,Akihisa Urano, General and comparative endocrinology, Vol. 143, No. 2, p. 129-41, 2005/09/01
  • Elevation of gene expression for salmon gonadotropin-releasing hormone in discrete brain loci of prespawning chum salmon during upstream migration., Takeshi Onuma,Mikihiko Higa,Hironori Ando,Masatoshi Ban,Akihisa Urano, Journal of neurobiology, Vol. 63, No. 2, p. 126-45, 2005/05
  • Year-to-year differences in plasma levels of steroid hormones in pre-spawning chum salmon., Takeshi Onuma,Yoshitatsu Higashi,Hironori Ando,Masatoshi Ban,Hiroshi Ueda,Akihisa Urano, General and comparative endocrinology, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 133, No. 2, p. 199-215, 2003/09
  • Changes in expression of genes encoding gonadotropin subunits and growth hormone/prolactin/somatolactin family hormones during final maturation and freshwater adaptation in prespawning chum salmon, Takeshi Onuma,Takashi Kitahashi,Shinya Taniyama,Daisuke Saito,Hironori Ando,Akihisa Urano, Endocrine, Vol. 20, No. 1-2, p. 23-33, 2003/02

Awards

  • The Jimmie Dodd Memorial Prize, Onuma TA, 2005/05
  • 第31回日本比較内分泌学会 最優秀発表賞 (共著者), 2006/11
  • Zoological Science Award 2009, 2009/06
  • The Endocrine Society Outstanding Abstract Award, Onuma TA, Endo 2010: The 92th Annual Society and Expo, 2010/06
  • The 3rd Annual Meeting of Whole-Organism Science Society Joint meeting with The 12th Annual Meeting of Structural-Biological Whole Cell Project 優秀発表賞, Onuma TA,Kishi K,Omotezako T,Nishida H, 2013/09
  • 2020 日本動物学会奨励賞, 2020/09